-
1
-
-
84925854840
-
Reactive oxygen species in pathogenesis of atherosclerosis
-
Nikolay VG, Pavel VA, Alexander DN, Irina LZ, Richard OJ. Reactive oxygen species in pathogenesis of atherosclerosis. Curr Pharm Des. 2015;21:1134-1146.
-
(2015)
Curr Pharm Des
, vol.21
, pp. 1134-1146
-
-
Nikolay, V.G.1
Pavel, V.A.2
Alexander, D.N.3
Irina, L.Z.4
Richard, O.J.5
-
2
-
-
77952480033
-
Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis
-
Kaneto H, Katakami N, Matsuhisa M, Matsuoka TA. Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis. Mediators Inflamm. 2010;2010:453892. doi: 10.1155/2010/453892.
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 453892
-
-
Kaneto, H.1
Katakami, N.2
Matsuhisa, M.3
Matsuoka, T.A.4
-
3
-
-
77449152992
-
Oxidative stress and its role in the pathogenesis of ischaemic stroke
-
Allen CL, Bayraktutan U. Oxidative stress and its role in the pathogenesis of ischaemic stroke. Int J Stroke. 2009;4:461-470. doi: 10.1111/j.1747-4949.2009.00387.x.
-
(2009)
Int J Stroke
, vol.4
, pp. 461-470
-
-
Allen, C.L.1
Bayraktutan, U.2
-
4
-
-
33846794822
-
The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
-
Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev. 2007;87:245-313. doi: 10.1152/physrev.00044.2005.
-
(2007)
Physiol Rev
, vol.87
, pp. 245-313
-
-
Bedard, K.1
Krause, K.H.2
-
5
-
-
84920520188
-
NADPH oxidases: An overview from structure to innate immunity-associated pathologies
-
Panday A, Sahoo MK, Osorio D, Batra S. NADPH oxidases: an overview from structure to innate immunity-associated pathologies. Cell Mol Immunol. 2015;12:5-23. doi: 10.1038/cmi.2014.89.
-
(2015)
Cell Mol Immunol
, vol.12
, pp. 5-23
-
-
Panday, A.1
Sahoo, M.K.2
Osorio, D.3
Batra, S.4
-
6
-
-
33745883797
-
NADPH oxidases in cardiovascular health and disease
-
Cave AC, Brewer AC, Narayanapanicker A, Ray R, Grieve DJ, Walker S, Shah AM. NADPH oxidases in cardiovascular health and disease. Antioxid Redox Signal. 2006;8:691-728. doi: 10.1089/ars.2006.8.691.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 691-728
-
-
Cave, A.C.1
Brewer, A.C.2
Narayanapanicker, A.3
Ray, R.4
Grieve, D.J.5
Walker, S.6
Shah, A.M.7
-
7
-
-
84994643802
-
Reactive oxygen species-driven HIF1α triggers accelerated glycolysis in endothelial cells exposed to low oxygen tension
-
Paik JY, Jung KH, Lee JH, Park JW, Lee KH. Reactive oxygen species-driven HIF1α triggers accelerated glycolysis in endothelial cells exposed to low oxygen tension. Nucl Med Biol. 2017;45:8-14. doi: 10.1016/j. nucmedbio.2016.10.006.
-
(2017)
Nucl Med Biol
, vol.45
, pp. 8-14
-
-
Paik, J.Y.1
Jung, K.H.2
Lee, J.H.3
Park, J.W.4
Lee, K.H.5
-
8
-
-
85011265828
-
Unexpected function of the phagocyte nadph oxidase in supporting hyperglycolysis in stimulated neutrophils: Key role of 6-phos-phofructo-2-kinase
-
Baillet A, Hograindleur M-A, El Benna J, Grichine A, Berthier S, Morel F, Paclet M-H. Unexpected function of the phagocyte nadph oxidase in supporting hyperglycolysis in stimulated neutrophils: key role of 6-phos-phofructo-2-kinase. FASEB J. 2016;31:663-673.
-
(2016)
FASEB J
, vol.31
, pp. 663-673
-
-
Baillet, A.1
Hograindleur, M.-A.2
El Benna, J.3
Grichine, A.4
Berthier, S.5
Morel, F.6
Paclet, M.-H.7
-
9
-
-
0032482975
-
Superoxide generation by endothelial nitric oxide synthase: The influence of cofactors
-
Vásquez-Vivar J, Kalyanaraman B, Martásek P, Hogg N, Masters BS, Karoui H, Tordo P, Pritchard KA Jr. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci USA. 1998;95:9220-9225.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9220-9225
-
-
Vásquez-Vivar, J.1
Kalyanaraman, B.2
Martásek, P.3
Hogg, N.4
Masters, B.S.5
Karoui, H.6
Tordo, P.7
Jr, P.K.A.8
-
10
-
-
68149137621
-
ENOS, metabolic syndrome and cardiovascular disease
-
Huang PL. eNOS, metabolic syndrome and cardiovascular disease. Trends Endocrinol Metab. 2009;20:295-302. doi: 10.1016/j.tem.2009.03.005.
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 295-302
-
-
Huang, P.L.1
-
11
-
-
0032575598
-
Inducible nitric-oxide synthase generates superoxide from the reductase domain
-
Xia Y, Roman LJ, Masters BS, Zweier JL. Inducible nitric-oxide synthase generates superoxide from the reductase domain. J Biol Chem. 1998;273:22635-22639.
-
(1998)
J Biol Chem
, vol.273
, pp. 22635-22639
-
-
Xia, Y.1
Roman, L.J.2
Masters, B.S.3
Zweier, J.L.4
-
12
-
-
0033515650
-
Mechanism of superoxide generation by neuronal nitric-oxide synthase
-
Pou S, Keaton L, Surichamorn W, Rosen GM. Mechanism of superoxide generation by neuronal nitric-oxide synthase. J Biol Chem. 1999;274:9573-9580.
-
(1999)
J Biol Chem
, vol.274
, pp. 9573-9580
-
-
Pou, S.1
Keaton, L.2
Surichamorn, W.3
Rosen, G.M.4
-
13
-
-
0037428488
-
Peroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection
-
García-Nogales P, Almeida A, Bolaños JP. Peroxynitrite protects neurons against nitric oxide-mediated apoptosis. A key role for glucose-6-phosphate dehydrogenase activity in neuroprotection. J Biol Chem. 2003;278:864-874. doi: 10.1074/jbc.M206835200.
-
(2003)
J Biol Chem
, vol.278
, pp. 864-874
-
-
García-Nogales, P.1
Almeida, A.2
Bolaños, J.P.3
-
14
-
-
0032838733
-
The detoxification of cumene hy-droperoxide by the glutathione system of cultured astroglial cells hinges on hexose availability for the regeneration of NADPH
-
Kussmaul L, Hamprecht B, Dringen R. The detoxification of cumene hy-droperoxide by the glutathione system of cultured astroglial cells hinges on hexose availability for the regeneration of NADPH. J Neurochem. 1999;73:1246-1253.
-
(1999)
J Neurochem
, vol.73
, pp. 1246-1253
-
-
Kussmaul, L.1
Hamprecht, B.2
Dringen, R.3
-
15
-
-
84878983557
-
Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress
-
Ham M, Lee JW, Choi AH, Jang H, Choi G, Park J, Kozuka C, Sears DD, Masuzaki H, Kim JB. Macrophage glucose-6-phosphate dehydrogenase stimulates proinflammatory responses with oxidative stress. Mol Cell Biol. 2013;33:2425-2435. doi: 10.1128/MCB.01260-12.
-
(2013)
Mol Cell Biol
, vol.33
, pp. 2425-2435
-
-
Ham, M.1
Lee, J.W.2
Choi, A.H.3
Jang, H.4
Choi, G.5
Park, J.6
Kozuka, C.7
Sears, D.D.8
Masuzaki, H.9
Kim, J.B.10
-
16
-
-
22144461029
-
Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II
-
Matsui R, Xu S, Maitland KA, Hayes A, Leopold JA, Handy DE, Loscalzo J, Cohen RA. Glucose-6 phosphate dehydrogenase deficiency decreases the vascular response to angiotensin II. Circulation. 2005;112:257-263. doi: 10.1161/CIRCULATIONAHA.104.499095.
-
(2005)
Circulation
, vol.112
, pp. 257-263
-
-
Matsui, R.1
Xu, S.2
Maitland, K.A.3
Hayes, A.4
Leopold, J.A.5
Handy, D.E.6
Loscalzo, J.7
Cohen, R.A.8
-
17
-
-
84869767236
-
Increasing glucose 6-phosphate dehydrogenase activity restores redox balance in vascular endothelial cells exposed to high glucose
-
Zhang Z, Yang Z, Zhu B, Hu J, Liew CW, Zhang Y, Leopold JA, Handy DE, Loscalzo J, Stanton RC. Increasing glucose 6-phosphate dehydrogenase activity restores redox balance in vascular endothelial cells exposed to high glucose. PLoS One. 2012;7:e49128. doi: 10.1371/journal.pone.0049128.
-
(2012)
PLoS One
, vol.7
, pp. e49128
-
-
Zhang, Z.1
Yang, Z.2
Zhu, B.3
Hu, J.4
Liew, C.W.5
Zhang, Y.6
Leopold, J.A.7
Handy, D.E.8
Loscalzo, J.9
Stanton, R.C.10
-
18
-
-
84860296724
-
AMP-activated protein kinase, stress responses and cardiovascular diseases
-
Lond
-
Wang S, Song P, Zou MH. AMP-activated protein kinase, stress responses and cardiovascular diseases. Clin Sci (Lond). 2012;122:555-573. doi: 10.1042/CS20110625.
-
(2012)
Clin Sci (
, vol.122
, pp. 555-573
-
-
Wang, S.1
Song, P.2
Zou, M.H.3
-
19
-
-
80052511813
-
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
-
Mihaylova MM, Shaw RJ. The AMPK signalling pathway coordinates cell growth, autophagy and metabolism. Nat Cell Biol. 2011;13:1016-1023. doi: 10.1038/ncb2329.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1016-1023
-
-
Mihaylova, M.M.1
Shaw, R.J.2
-
20
-
-
80052317552
-
Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels
-
Mungai PT, Waypa GB, Jairaman A, Prakriya M, Dokic D, Ball MK, Schumacker PT. Hypoxia triggers AMPK activation through reactive oxygen species-mediated activation of calcium release-activated calcium channels. Mol Cell Biol. 2011;31:3531-3545. doi: 10.1128/MCB.05124-11.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3531-3545
-
-
Mungai, P.T.1
Waypa, G.B.2
Jairaman, A.3
Prakriya, M.4
Dokic, D.5
Ball, M.K.6
Schumacker, P.T.7
-
21
-
-
77958501463
-
Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase
-
Zmijewski JW, Banerjee S, Bae H, Friggeri A, Lazarowski ER, Abraham E. Exposure to hydrogen peroxide induces oxidation and activation of AMP-activated protein kinase. J Biol Chem. 2010;285:33154-33164. doi: 10.1074/jbc.M110.143685.
-
(2010)
J Biol Chem
, vol.285
, pp. 33154-33164
-
-
Zmijewski, J.W.1
Banerjee, S.2
Bae, H.3
Friggeri, A.4
Lazarowski, E.R.5
Abraham, E.6
-
22
-
-
84862849835
-
Redox implications of AMPK-mediated signal transduction beyond energetic clues
-
Cardaci S, Filomeni G, Ciriolo MR. Redox implications of AMPK-mediated signal transduction beyond energetic clues. J Cell Sci. 2012;125:2115-2125. doi: 10.1242/jcs.095216.
-
(2012)
J Cell Sci
, vol.125
, pp. 2115-2125
-
-
Cardaci, S.1
Filomeni, G.2
Ciriolo, M.R.3
-
23
-
-
0141706665
-
Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite
-
Zou MH, Hou XY, Shi CM, Kirkpatick S, Liu F, Goldman MH, Cohen RA. Activation of 5'-AMP-activated kinase is mediated through c-Src and phosphoinositide 3-kinase activity during hypoxia-reoxygenation of bovine aortic endothelial cells. Role of peroxynitrite. J Biol Chem. 2003;278:34003-34010. doi: 10.1074/jbc.M300215200.
-
(2003)
J Biol Chem
, vol.278
, pp. 34003-34010
-
-
Zou, M.H.1
Hou, X.Y.2
Shi, C.M.3
Kirkpatick, S.4
Liu, F.5
Goldman, M.H.6
Cohen, R.A.7
-
24
-
-
82755166890
-
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
-
Anastasiou D, Poulogiannis G, Asara JM, Boxer MB, Jiang JK, Shen M, Bellinger G, Sasaki AT, Locasale JW, Auld DS, Thomas CJ, Vander Heiden MG, Cantley LC. Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. Science. 2011;334:1278-1283. doi: 10.1126/science.1211485.
-
(2011)
Science
, vol.334
, pp. 1278-1283
-
-
Anastasiou, D.1
Poulogiannis, G.2
Asara, J.M.3
Boxer, M.B.4
Jiang, J.K.5
Shen, M.6
Bellinger, G.7
Sasaki, A.T.8
Locasale, J.W.9
Auld, D.S.10
Thomas, C.J.11
Vander Heiden, M.G.12
Cantley, L.C.13
-
25
-
-
79952184583
-
Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS)
-
Bulua AC, Simon A, Maddipati R, Pelletier M, Park H, Kim KY, Sack MN, Kastner DL, Siegel RM. Mitochondrial reactive oxygen species promote production of proinflammatory cytokines and are elevated in TNFR1-associated periodic syndrome (TRAPS). J Exp Med. 2011;208:519-533. doi: 10.1084/jem.20102049.
-
(2011)
J Exp Med
, vol.208
, pp. 519-533
-
-
Bulua, A.C.1
Simon, A.2
Maddipati, R.3
Pelletier, M.4
Park, H.5
Kim, K.Y.6
Sack, M.N.7
Kastner, D.L.8
Siegel, R.M.9
-
26
-
-
33846407051
-
Impact of mitochondrial ROS production in the pathogenesis of diabetes mellitus and its complications
-
Nishikawa T, Araki E. Impact of mitochondrial ROS production in the pathogenesis of diabetes mellitus and its complications. Antioxid Redox Signal. 2007;9:343-353. doi: 10.1089/ars.2007.9.ft-19.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 343-353
-
-
Nishikawa, T.1
Araki, E.2
-
27
-
-
33646716659
-
The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria
-
Kussmaul L, Hirst J. The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci USA. 2006;103:7607-7612.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 7607-7612
-
-
Kussmaul, L.1
Hirst, J.2
-
28
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy Michael P. How mitochondria produce reactive oxygen species. Biochem J. 2009;417:1-13.
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy Michael, P.1
-
29
-
-
84884669583
-
Superoxide generation by complex III: From mechanistic rationales to functional consequences
-
Bleier L, Dröse S. Superoxide generation by complex III: from mechanistic rationales to functional consequences. Biochim Biophys Acta. 2013;1827:1320-1331. doi: 10.1016/j.bbabio.2012.12.002.
-
(2013)
Biochim Biophys Acta
, vol.1827
, pp. 1320-1331
-
-
Bleier, L.1
Dröse, S.2
-
30
-
-
84864540083
-
Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions
-
Quinlan CL, Orr AL, Perevoshchikova IV, Treberg JR, Ackrell BA, Brand MD. Mitochondrial complex II can generate reactive oxygen species at high rates in both the forward and reverse reactions. J Biol Chem. 2012;287:27255-27264. doi: 10.1074/jbc.M112.374629.
-
(2012)
J Biol Chem
, vol.287
, pp. 27255-27264
-
-
Quinlan, C.L.1
Orr, A.L.2
Perevoshchikova, I.V.3
Treberg, J.R.4
Ackrell, B.A.5
Brand, M.D.6
-
31
-
-
85002949454
-
Mitochondrial reactive oxygen species and inflammation: Molecular mechanisms, diseases and promising therapies
-
Rimessi A, Previati M, Nigro F, Wieckowski MR, Pinton P. Mitochondrial reactive oxygen species and inflammation: molecular mechanisms, diseases and promising therapies. Int J Biochem Cell Biol. 2016;81:281-293. doi: 10.1016/j.biocel.2016.06.015.
-
(2016)
Int J Biochem Cell Biol
, vol.81
, pp. 281-293
-
-
Rimessi, A.1
Previati, M.2
Nigro, F.3
Wieckowski, M.R.4
Pinton, P.5
-
32
-
-
79960286223
-
Signal transduction by reactive oxygen species
-
Finkel T. Signal transduction by reactive oxygen species. J Cell Biol. 2011;194:7-15. doi: 10.1083/jcb.201102095.
-
(2011)
J Cell Biol
, vol.194
, pp. 7-15
-
-
Finkel, T.1
-
33
-
-
4544359913
-
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species
-
Starkov AA, Fiskum G, Chinopoulos C, Lorenzo BJ, Browne SE, Patel MS, Beal MF. Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. J Neurosci. 2004;24:7779-7788. doi: 10.1523/JNEUROSCI.1899-04.2004.
-
(2004)
J Neurosci
, vol.24
, pp. 7779-7788
-
-
Starkov, A.A.1
Fiskum, G.2
Chinopoulos, C.3
Lorenzo, B.J.4
Browne, S.E.5
Patel, M.S.6
Beal, M.F.7
-
34
-
-
84978886200
-
2-Oxoglutarate dehydrogenase is a more significant source of O2(·-)/H2O2 than pyruvate dehydrogenase in cardiac and liver tissue
-
Mailloux RJ, Gardiner D, O'Brien M. 2-Oxoglutarate dehydrogenase is a more significant source of O2(·-)/H2O2 than pyruvate dehydrogenase in cardiac and liver tissue. Free Radic Biol Med. 2016;97:501-512. doi: 10.1016/j.freeradbiomed.2016.06.014.
-
(2016)
Free Radic Biol Med
, vol.97
, pp. 501-512
-
-
Mailloux, R.J.1
Gardiner, D.2
O'Brien, M.3
-
35
-
-
84896935583
-
The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I
-
Quinlan CL, Goncalves RL, Hey-Mogensen M, Yadava N, Bunik VI, Brand MD. The 2-oxoacid dehydrogenase complexes in mitochondria can produce superoxide/hydrogen peroxide at much higher rates than complex I. J Biol Chem. 2014;289:8312-8325. doi: 10.1074/jbc.M113.545301.
-
(2014)
J Biol Chem
, vol.289
, pp. 8312-8325
-
-
Quinlan, C.L.1
Goncalves, R.L.2
Hey-Mogensen, M.3
Yadava, N.4
Bunik, V.I.5
Brand, M.D.6
-
36
-
-
85014054569
-
Protein S-glutathionylation alters superoxide/hydrogen peroxide emission from pyruvate dehydrogenase complex
-
O'Brien M, Chalker J, Slade L, Gardiner D, Mailloux RJ. Protein S-glutathionylation alters superoxide/hydrogen peroxide emission from pyruvate dehydrogenase complex. Free Radic Biol Med. 2017;106:302-314. doi: 10.1016/j.freeradbiomed.2017.02.046.
-
(2017)
Free Radic Biol Med
, vol.106
, pp. 302-314
-
-
O'Brien, M.1
Chalker, J.2
Slade, L.3
Gardiner, D.4
Mailloux, R.J.5
-
37
-
-
33745252231
-
Alpha-ketoglutarate dehydrogenase: A target and generator of oxidative stress
-
Tretter L, Adam-Vizi V. Alpha-ketoglutarate dehydrogenase: a target and generator of oxidative stress. Philos Trans R Soc Lond B Biol Sci. 2005;360:2335-2345. doi: 10.1098/rstb.2005.1764.
-
(2005)
Philos Trans R Soc Lond B Biol Sci
, vol.360
, pp. 2335-2345
-
-
Tretter, L.1
Adam-Vizi, V.2
-
38
-
-
0034671429
-
Inhibition of Krebs cycle enzymes by hydrogen peroxide: A key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress
-
Tretter L, Adam-Vizi V. Inhibition of Krebs cycle enzymes by hydrogen peroxide: a key role of [alpha]-ketoglutarate dehydrogenase in limiting NADH production under oxidative stress. J Neurosci. 2000;20:8972-8979.
-
(2000)
J Neurosci
, vol.20
, pp. 8972-8979
-
-
Tretter, L.1
Adam-Vizi, V.2
-
39
-
-
84867407574
-
Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species
-
Hurd TR, Collins Y, Abakumova I, Chouchani ET, Baranowski B, Fearnley IM, Prime TA, Murphy MP, James AM. Inactivation of pyruvate dehydrogenase kinase 2 by mitochondrial reactive oxygen species. J Biol Chem. 2012;287:35153-35160. doi: 10.1074/jbc.M112.400002.
-
(2012)
J Biol Chem
, vol.287
, pp. 35153-35160
-
-
Hurd, T.R.1
Collins, Y.2
Abakumova, I.3
Chouchani, E.T.4
Baranowski, B.5
Fearnley, I.M.6
Prime, T.A.7
Murphy, M.P.8
James, A.M.9
-
40
-
-
63049130752
-
Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart
-
Lin G, Brownsey RW, MacLeod KM. Regulation of mitochondrial aconitase by phosphorylation in diabetic rat heart. Cell Mol Life Sci. 2009;66:919-932. doi: 10.1007/s00018-009-8696-3.
-
(2009)
Cell Mol Life Sci
, vol.66
, pp. 919-932
-
-
Lin, G.1
Brownsey, R.W.2
MacLeod, K.M.3
-
41
-
-
77951281040
-
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes
-
Ago T, Kuroda J, Pain J, Fu C, Li H, Sadoshima J. Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. Circ Res. 2010;106:1253-1264. doi: 10.1161/ CIRCRESAHA.109.213116.
-
(2010)
Circ Res
, vol.106
, pp. 1253-1264
-
-
Ago, T.1
Kuroda, J.2
Pain, J.3
Fu, C.4
Li, H.5
Sadoshima, J.6
-
42
-
-
85013478403
-
NADPH oxidase 4 (Nox4) suppresses mitochondrial biogenesis and bioenergetics in lung fibroblasts via a nuclear factor erythroid-derived 2-like 2 (Nrf2)-dependent pathway
-
Bernard K, Logsdon NJ, Miguel V, Benavides GA, Zhang J, Carter AB, Darley-Usmar VM, Thannickal VJ. NADPH oxidase 4 (Nox4) suppresses mitochondrial biogenesis and bioenergetics in lung fibroblasts via a nuclear factor erythroid-derived 2-like 2 (Nrf2)-dependent pathway. J Biol Chem. 2017;292:3029-3038. doi: 10.1074/jbc.M116.752261.
-
(2017)
J Biol Chem
, vol.292
, pp. 3029-3038
-
-
Bernard, K.1
Logsdon, N.J.2
Miguel, V.3
Benavides, G.A.4
Zhang, J.5
Carter, A.B.6
Darley-Usmar, V.M.7
Thannickal, V.J.8
-
43
-
-
85031907733
-
NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance
-
Shanmugasundaram K, Nayak BK, Friedrichs WE, Kaushik D, Rodriguez R, Block K. NOX4 functions as a mitochondrial energetic sensor coupling cancer metabolic reprogramming to drug resistance. Nat Commun. 2017;8:997. doi: 10.1038/s41467-017-01106-1.
-
(2017)
Nat Commun
, vol.8
, pp. 997
-
-
Shanmugasundaram, K.1
Nayak, B.K.2
Friedrichs, W.E.3
Kaushik, D.4
Rodriguez, R.5
Block, K.6
-
44
-
-
73449124480
-
Mitochondrial glutathione, a key survival antioxidant
-
Marí M, Morales A, Colell A, García-Ruiz C, Fernández-Checa JC. Mitochondrial glutathione, a key survival antioxidant. Antioxid Redox Signal. 2009;11:2685-2700. doi: 10.1089/ARS.2009.2695.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2685-2700
-
-
Marí, M.1
Morales, A.2
Colell, A.3
García-Ruiz, C.4
Fernández-Checa, J.C.5
-
45
-
-
79961193678
-
Superoxide dismutases: Role in redox signaling, vascular function, and diseases
-
Fukai T, Ushio-Fukai M. Superoxide dismutases: role in redox signaling, vascular function, and diseases. Antioxid Redox Signal. 2011;15:1583-1606. doi: 10.1089/ars.2011.3999.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 1583-1606
-
-
Fukai, T.1
Ushio-Fukai, M.2
-
47
-
-
34548048824
-
Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress
-
Zhang H, Go YM, Jones DP. Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress. Arch Biochem Biophys. 2007;465:119-126. doi: 10.1016/j.abb.2007.05.001.
-
(2007)
Arch Biochem Biophys
, vol.465
, pp. 119-126
-
-
Zhang, H.1
Go, Y.M.2
Jones, D.P.3
-
48
-
-
39149137166
-
Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress
-
Pérez VI, Lew CM, Cortez LA, Webb CR, Rodriguez M, Liu Y, Qi W, Li Y, Chaudhuri A, Van Remmen H, Richardson A, Ikeno Y. Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress. Free Radic Biol Med. 2008;44:882-892. doi: 10.1016/j.freeradbiomed.2007.11.018.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 882-892
-
-
Pérez, V.I.1
Lew, C.M.2
Cortez, L.A.3
Webb, C.R.4
Rodriguez, M.5
Liu, Y.6
Qi, W.7
Li, Y.8
Chaudhuri, A.9
Van Remmen, H.10
Richardson, A.11
Ikeno, Y.12
-
49
-
-
85021308174
-
Heart-specific knockout of the mitochondrial thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction in the aging myocardium
-
Kiermayer C, Northrup E, Schrewe A, Walch A, de Angelis MH, Schoensiegel F, Zischka H, Prehn C, Adamski J, Bekeredjian R, Ivandic B, Kupatt C, Brielmeier M. Heart-specific knockout of the mitochondrial thioredoxin reductase (Txnrd2) induces metabolic and contractile dysfunction in the aging myocardium. J Am Heart Assoc. 2015;4:e002153.
-
(2015)
J Am Heart Assoc
, vol.4
, pp. e002153
-
-
Kiermayer, C.1
Northrup, E.2
Schrewe, A.3
Walch, A.4
De Angelis, M.H.5
Schoensiegel, F.6
Zischka, H.7
Prehn, C.8
Adamski, J.9
Bekeredjian, R.10
Ivandic, B.11
Kupatt, C.12
Brielmeier, M.13
-
50
-
-
0036226063
-
Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes
-
Rodríguez-Manzaneque MT, Tamarit J, Bellí G, Ros J, Herrero E. Grx5 is a mitochondrial glutaredoxin required for the activity of iron/sulfur enzymes. Mol Biol Cell. 2002;13:1109-1121. doi: 10.1091/mbc.01-10-0517.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 1109-1121
-
-
Rodríguez-Manzaneque, M.T.1
Tamarit, J.2
Bellí, G.3
Ros, J.4
Herrero, E.5
-
51
-
-
33847746679
-
Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: Implications for diseases in the cardiovascular system
-
Berndt C, Lillig CH, Holmgren A. Thiol-based mechanisms of the thioredoxin and glutaredoxin systems: implications for diseases in the cardiovascular system. Am J Physiol Heart Circ Physiol. 2007;292:H1227-H1236. doi: 10.1152/ajpheart.01162.2006.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
, pp. H1227-H1236
-
-
Berndt, C.1
Lillig, C.H.2
Holmgren, A.3
-
52
-
-
9144249116
-
Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: Implications for mitochondrial redox regulation and antioxidant DEFENSE
-
Beer SM, Taylor ER, Brown SE, Dahm CC, Costa NJ, Runswick MJ, Murphy MP. Glutaredoxin 2 catalyzes the reversible oxidation and glutathionylation of mitochondrial membrane thiol proteins: implications for mitochondrial redox regulation and antioxidant DEFENSE. J Biol Chem. 2004;279:47939-47951. doi: 10.1074/jbc.M408011200.
-
(2004)
J Biol Chem
, vol.279
, pp. 47939-47951
-
-
Beer, S.M.1
Taylor, E.R.2
Brown, S.E.3
Dahm, C.C.4
Costa, N.J.5
Runswick, M.J.6
Murphy, M.P.7
-
53
-
-
84957439277
-
TCA cycle and mitochondrial membrane potential are necessary for diverse biological functions
-
Martínez-Reyes I, Diebold LP, Kong H, et al. TCA cycle and mitochondrial membrane potential are necessary for diverse biological functions. Mol Cell. 2016;61:199-209. doi: 10.1016/j.molcel.2015.12.002.
-
(2016)
Mol Cell
, vol.61
, pp. 199-209
-
-
Martínez-Reyes, I.1
Diebold, L.P.2
Kong, H.3
-
54
-
-
77953809481
-
Hypoxia and mitochondrial oxidative metabolism
-
Solaini G, Baracca A, Lenaz G, Sgarbi G. Hypoxia and mitochondrial oxidative metabolism. Biochim Biophys Acta. 2010;1797:1171-1177. doi: 10.1016/j.bbabio.2010.02.011.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 1171-1177
-
-
Solaini, G.1
Baracca, A.2
Lenaz, G.3
Sgarbi, G.4
-
55
-
-
33644614520
-
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
-
Kim JW, Tchernyshyov I, Semenza GL, Dang CV. HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab. 2006;3:177-185. doi: 10.1016/j.cmet.2006.02.002.
-
(2006)
Cell Metab
, vol.3
, pp. 177-185
-
-
Kim, J.W.1
Tchernyshyov, I.2
Semenza, G.L.3
Dang, C.V.4
-
56
-
-
34247631690
-
The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis
-
Lum JJ, Bui T, Gruber M, Gordan JD, DeBerardinis RJ, Covello KL, Simon MC, Thompson CB. The transcription factor HIF-1alpha plays a critical role in the growth factor-dependent regulation of both aerobic and anaerobic glycolysis. Genes Dev. 2007;21:1037-1049. doi: 10.1101/ gad.1529107.
-
(2007)
Genes Dev
, vol.21
, pp. 1037-1049
-
-
Lum, J.J.1
Bui, T.2
Gruber, M.3
Gordan, J.D.4
DeBerardinis, R.J.5
Covello, K.L.6
Simon, M.C.7
Thompson, C.B.8
-
57
-
-
79957952535
-
Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
-
Semenza GL. Hypoxia-inducible factor 1: regulator of mitochondrial metabolism and mediator of ischemic preconditioning. Biochim Biophys Acta. 2011;1813:1263-1268. doi: 10.1016/j.bbamcr.2010.08.006.
-
(2011)
Biochim Biophys Acta
, vol.1813
, pp. 1263-1268
-
-
Semenza, G.L.1
-
58
-
-
43649104579
-
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia
-
Zhang H, Bosch-Marce M, Shimoda LA, Tan YS, Baek JH, Wesley JB, Gonzalez FJ, Semenza GL. Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia. J Biol Chem. 2008;283:10892-10903. doi: 10.1074/jbc.M800102200.
-
(2008)
J Biol Chem
, vol.283
, pp. 10892-10903
-
-
Zhang, H.1
Bosch-Marce, M.2
Shimoda, L.A.3
Tan, Y.S.4
Baek, J.H.5
Wesley, J.B.6
Gonzalez, F.J.7
Semenza, G.L.8
-
59
-
-
38349043984
-
Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species
-
Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB. Mitochondrial electron-transport-chain inhibitors of complexes I and II induce autophagic cell death mediated by reactive oxygen species. J Cell Sci. 2007;120:4155-4166. doi: 10.1242/jcs.011163.
-
(2007)
J Cell Sci
, vol.120
, pp. 4155-4166
-
-
Chen, Y.1
McMillan-Ward, E.2
Kong, J.3
Israels, S.J.4
Gibson, S.B.5
-
60
-
-
84943753597
-
Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling
-
Sinha RA, Singh BK, Zhou J, Wu Y, Farah BL, Ohba K, Lesmana R, Gooding J, Bay BH, Yen PM. Thyroid hormone induction of mitochondrial activity is coupled to mitophagy via ROS-AMPK-ULK1 signaling. Autophagy. 2015;11:1341-1357. doi: 10.1080/15548627.2015.1061849.
-
(2015)
Autophagy
, vol.11
, pp. 1341-1357
-
-
Sinha, R.A.1
Singh, B.K.2
Zhou, J.3
Wu, Y.4
Farah, B.L.5
Ohba, K.6
Lesmana, R.7
Gooding, J.8
Bay, B.H.9
Yen, P.M.10
-
61
-
-
34848920863
-
ROS, mitochondria and the regulation of autophagy
-
Scherz-Shouval R, Elazar Z. ROS, mitochondria and the regulation of autophagy. Trends Cell Biol. 2007;17:422-427. doi: 10.1016/j. tcb.2007.07.009.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 422-427
-
-
Scherz-Shouval, R.1
Elazar, Z.2
-
62
-
-
84908068704
-
Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans
-
Hwang AB, Ryu EA, Artan M, Chang HW, Kabir MH, Nam HJ, Lee D, Yang JS, Kim S, Mair WB, Lee C, Lee SS, Lee SJ. Feedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegans. Proc Natl Acad Sci USA. 2014;111:E4458-E4467.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. E4458-E4467
-
-
Hwang, A.B.1
Ryu, E.A.2
Artan, M.3
Chang, H.W.4
Kabir, M.H.5
Nam, H.J.6
Lee, D.7
Yang, J.S.8
Kim, S.9
Mair, W.B.10
Lee, C.11
Lee, S.S.12
Lee, S.J.13
-
63
-
-
54449091329
-
Early mitochondrial dysfunction in long-lived Mclk1+/- Mice
-
Lapointe J, Hekimi S. Early mitochondrial dysfunction in long-lived Mclk1+/- mice. J Biol Chem. 2008;283:26217-26227. doi: 10.1074/jbc. M803287200.
-
(2008)
J Biol Chem
, vol.283
, pp. 26217-26227
-
-
Lapointe, J.1
Hekimi, S.2
-
64
-
-
76249101651
-
Elevated mitochondrial reactive oxygen species generation affects the immune response via hypoxia-inducible factor-1alpha in long-lived Mclk1+/- Mouse mutants
-
Wang D, Malo D, Hekimi S. Elevated mitochondrial reactive oxygen species generation affects the immune response via hypoxia-inducible factor-1alpha in long-lived Mclk1+/- mouse mutants. J Immunol. 2010;184:582-590. doi: 10.4049/jimmunol.0902352.
-
(2010)
J Immunol
, vol.184
, pp. 582-590
-
-
Wang, D.1
Malo, D.2
Hekimi, S.3
-
66
-
-
84958850926
-
Mitochondrial dynamics and metabolic regulation
-
Wai T, Langer T. Mitochondrial dynamics and metabolic regulation. Trends Endocrinol Metab. 2016;27:105-117. doi: 10.1016/j.tem.2015.12.001.
-
(2016)
Trends Endocrinol Metab
, vol.27
, pp. 105-117
-
-
Wai, T.1
Langer, T.2
-
67
-
-
33644552417
-
Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
-
Yu T, Robotham JL, Yoon Y. Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology. Proc Natl Acad Sci USA. 2006;103:2653-2658. doi: 10.1073/pnas.0511154103.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2653-2658
-
-
Yu, T.1
Robotham, J.L.2
Yoon, Y.3
-
68
-
-
84897544422
-
Roles of mitochondrial fragmentation and reactive oxygen species in mitochondrial dysfunction and myocardial insulin resistance
-
Watanabe T, Saotome M, Nobuhara M, Sakamoto A, Urushida T, Katoh H, Satoh H, Funaki M, Hayashi H. Roles of mitochondrial fragmentation and reactive oxygen species in mitochondrial dysfunction and myocardial insulin resistance. Exp Cell Res. 2014;323:314-325. doi: 10.1016/j.yexcr.2014.02.027.
-
(2014)
Exp Cell Res
, vol.323
, pp. 314-325
-
-
Watanabe, T.1
Saotome, M.2
Nobuhara, M.3
Sakamoto, A.4
Urushida, T.5
Katoh, H.6
Satoh, H.7
Funaki, M.8
Hayashi, H.9
-
69
-
-
84874779519
-
Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus
-
Hong Z, Kutty S, Toth PT, Marsboom G, Hammel JM, Chamberlain C, Ryan JJ, Zhang HJ, Sharp WW, Morrow E, Trivedi K, Weir EK, Archer SL. Role of dynamin-related protein 1 (Drp1)-mediated mitochondrial fission in oxygen sensing and constriction of the ductus arteriosus. Circ Res. 2013;112:802-815. doi: 10.1161/CIRCRESAHA.111.300285.
-
(2013)
Circ Res
, vol.112
, pp. 802-815
-
-
Hong, Z.1
Kutty, S.2
Toth, P.T.3
Marsboom, G.4
Hammel, J.M.5
Chamberlain, C.6
Ryan, J.J.7
Zhang, H.J.8
Sharp, W.W.9
Morrow, E.10
Trivedi, K.11
Weir, E.K.12
Archer, S.L.13
-
70
-
-
79952520044
-
Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins
-
Wu S, Zhou F, Zhang Z, Xing D. Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins. FEBS J. 2011;278:941-954. doi: 10.1111/j.1742-4658.2011.08010.x.
-
(2011)
FEBS J
, vol.278
, pp. 941-954
-
-
Wu, S.1
Zhou, F.2
Zhang, Z.3
Xing, D.4
-
71
-
-
84867740975
-
Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner
-
Frank M, Duvezin-Caubet S, Koob S, Occhipinti A, Jagasia R, Petcherski A, Ruonala MO, Priault M, Salin B, Reichert AS. Mitophagy is triggered by mild oxidative stress in a mitochondrial fission dependent manner. Biochim Biophys Acta. 2012;1823:2297-2310. doi: 10.1016/j. bbamcr.2012.08.007.
-
(2012)
Biochim Biophys Acta
, vol.1823
, pp. 2297-2310
-
-
Frank, M.1
Duvezin-Caubet, S.2
Koob, S.3
Occhipinti, A.4
Jagasia, R.5
Petcherski, A.6
Ruonala, M.O.7
Priault, M.8
Salin, B.9
Reichert, A.S.10
-
72
-
-
84856244072
-
Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast
-
Kurihara Y, Kanki T, Aoki Y, Hirota Y, Saigusa T, Uchiumi T, Kang D. Mitophagy plays an essential role in reducing mitochondrial production of reactive oxygen species and mutation of mitochondrial DNA by maintaining mitochondrial quantity and quality in yeast. J Biol Chem. 2012;287:3265-3272. doi: 10.1074/jbc.M111.280156.
-
(2012)
J Biol Chem
, vol.287
, pp. 3265-3272
-
-
Kurihara, Y.1
Kanki, T.2
Aoki, Y.3
Hirota, Y.4
Saigusa, T.5
Uchiumi, T.6
Kang, D.7
-
73
-
-
84855462583
-
Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: Role of nitric oxide and reactive oxygen species
-
Giedt RJ, Yang C, Zweier JL, Matzavinos A, Alevriadou BR. Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: role of nitric oxide and reactive oxygen species. Free Radic Biol Med. 2012;52:348-356. doi: 10.1016/j.freeradbiomed.2011.10.491.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 348-356
-
-
Giedt, R.J.1
Yang, C.2
Zweier, J.L.3
Matzavinos, A.4
Alevriadou, B.R.5
-
74
-
-
84941600324
-
Regulation of mitochondrial morphology by positive feedback interaction between PKCδ and Drp1 in vascular smooth muscle cell
-
Lim S, Lee SY, Seo HH, Ham O, Lee C, Park JH, Lee J, Seung M, Yun I, Han SM, Lee S, Choi E, Hwang KC. Regulation of mitochondrial morphology by positive feedback interaction between PKCδ and Drp1 in vascular smooth muscle cell. J Cell Biochem. 2015;116:648-660. doi: 10.1002/jcb.25016.
-
(2015)
J Cell Biochem
, vol.116
, pp. 648-660
-
-
Lim, S.1
Lee, S.Y.2
Seo, H.H.3
Ham, O.4
Lee, C.5
Park, J.H.6
Lee, J.7
Seung, M.8
Yun, I.9
Han, S.M.10
Lee, S.11
Choi, E.12
Hwang, K.C.13
-
75
-
-
85032003962
-
P47Phox/CDK5/DRP1-mediated mitochondrial fission evokes PV cell degeneration in the rat dentate gyrus following status epilepticus
-
Kim JE, Kang TC. p47Phox/CDK5/DRP1-mediated mitochondrial fission evokes PV cell degeneration in the rat dentate gyrus following status epilepticus. Front Cell Neurosci. 2017;11:267. doi: 10.3389/ fncel.2017.00267.
-
(2017)
Front Cell Neurosci
, vol.11
, pp. 267
-
-
Kim, J.E.1
Kang, T.C.2
-
76
-
-
84894475127
-
ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics
-
Norton M, Ng AC, Baird S, Dumoulin A, Shutt T, Mah N, Andrade-Navarro MA, McBride HM, Screaton RA. ROMO1 is an essential redox-dependent regulator of mitochondrial dynamics. Sci Signal. 2014;7:ra10. doi: 10.1126/scisignal.2004374.
-
(2014)
Sci Signal
, vol.7
, pp. ra10
-
-
Norton, M.1
Ng, A.C.2
Baird, S.3
Dumoulin, A.4
Shutt, T.5
Mah, N.6
Andrade-Navarro, M.A.7
McBride, H.M.8
Screaton, R.A.9
-
77
-
-
84887212354
-
Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production
-
Tang S, Le PK, Tse S, Wallace DC, Huang T. Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production. PLoS One. 2009;4:e4492. doi: 10.1371/ journal.pone.0004492.
-
(2009)
PLoS One
, vol.4
, pp. e4492
-
-
Tang, S.1
Le, P.K.2
Tse, S.3
Wallace, D.C.4
Huang, T.5
-
78
-
-
34548170490
-
Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis
-
Shen T, Zheng M, Cao C, Chen C, Tang J, Zhang W, Cheng H, Chen KH, Xiao RP. Mitofusin-2 is a major determinant of oxidative stress-mediated heart muscle cell apoptosis. J Biol Chem. 2007;282:23354-23361. doi: 10.1074/jbc.M702657200.
-
(2007)
J Biol Chem
, vol.282
, pp. 23354-23361
-
-
Shen, T.1
Zheng, M.2
Cao, C.3
Chen, C.4
Tang, J.5
Zhang, W.6
Cheng, H.7
Chen, K.H.8
Xiao, R.P.9
-
79
-
-
84255192658
-
Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death
-
Papanicolaou KN, Ngoh GA, Dabkowski ER, O'Connell KA, Ribeiro RF Jr, Stanley WC, Walsh K. Cardiomyocyte deletion of mitofusin-1 leads to mitochondrial fragmentation and improves tolerance to ROS-induced mitochondrial dysfunction and cell death. Am J Physiol Heart Circ Physiol. 2012;302:H167-H179. doi: 10.1152/ajpheart.00833.2011.
-
(2012)
Am J Physiol Heart Circ Physiol
, vol.302
, pp. H167-H179
-
-
Papanicolaou, K.N.1
Ngoh, G.A.2
Dabkowski, E.R.3
O'Connell, K.A.4
Jr, R.R.F.5
Stanley, W.C.6
Walsh, K.7
-
81
-
-
33746366462
-
Biochemistry of mammalian peroxisomes revisited
-
Wanders RJ, Waterham HR. Biochemistry of mammalian peroxisomes revisited. Annu Rev Biochem. 2006;75:295-332. doi: 10.1146/annurev. biochem.74.082803.133329.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 295-332
-
-
Wanders, R.J.1
Waterham, H.R.2
-
82
-
-
70449715463
-
Reactive oxygen species and peroxisomes: Struggling for balance
-
Bonekamp NA, Völkl A, Fahimi HD, Schrader M. Reactive oxygen species and peroxisomes: struggling for balance. Biofactors. 2009;35:346-355. doi: 10.1002/biof.48.
-
(2009)
Biofactors
, vol.35
, pp. 346-355
-
-
Bonekamp, N.A.1
Völkl, A.2
Fahimi, H.D.3
Schrader, M.4
-
83
-
-
84864050485
-
Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease
-
Fransen M, Nordgren M, Wang B, Apanasets O. Role of peroxisomes in ROS/RNS-metabolism: implications for human disease. Biochim Biophys Acta. 2012;1822:1363-1373. doi: 10.1016/j.bbadis.2011.12.001.
-
(2012)
Biochim Biophys Acta
, vol.1822
, pp. 1363-1373
-
-
Fransen, M.1
Nordgren, M.2
Wang, B.3
Apanasets, O.4
-
84
-
-
25444518977
-
Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes
-
Loughran P, Stolz D, Vodovotz Y, Watkins S, Simmons R, Billiar T. Monomeric inducible nitric oxide synthase localizes to peroxisomes in hepatocytes. Proc Natl Acad Sci USA. 2005;102:13837-13842.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 13837-13842
-
-
Loughran, P.1
Stolz, D.2
Vodovotz, Y.3
Watkins, S.4
Simmons, R.5
Billiar, T.6
-
85
-
-
33845292901
-
Peroxisomes and oxidative stress
-
Schrader M, Fahimi HD. Peroxisomes and oxidative stress. Biochim Biophys Acta. 2006;1763:1755-1766. doi: 10.1016/j.bbamcr.2006.09.006.
-
(2006)
Biochim Biophys Acta
, vol.1763
, pp. 1755-1766
-
-
Schrader, M.1
Fahimi, H.D.2
-
86
-
-
84885105969
-
A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS
-
Zhang J, Kim J, Alexander A, et al. A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS. Nat Cell Biol. 2013;15:1186-1196. doi: 10.1038/ncb2822.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 1186-1196
-
-
Zhang, J.1
Kim, J.2
Alexander, A.3
-
87
-
-
84942982653
-
ATM functions at the peroxisome to induce pexophagy in response to ROS
-
Zhang J, Tripathi DN, Jing J, Alexander A, Kim J, Powell RT, Dere R, Tait-Mulder J, Lee JH, Paull TT, Pandita RK, Charaka VK, Pandita TK, Kastan MB, Walker CL. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269. doi: 10.1038/ncb3230.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 1259-1269
-
-
Zhang, J.1
Tripathi, D.N.2
Jing, J.3
Alexander, A.4
Kim, J.5
Powell, R.T.6
Dere, R.7
Tait-Mulder, J.8
Lee, J.H.9
Paull, T.T.10
Pandita, R.K.11
Charaka, V.K.12
Pandita, T.K.13
Kastan, M.B.14
Walker, C.L.15
-
88
-
-
79955506970
-
Intraperoxisomal redox balance in mammalian cells: Oxidative stress and interorganellar cross-talk
-
Ivashchenko O, Van Veldhoven PP, Brees C, Ho YS, Terlecky SR, Fransen M. Intraperoxisomal redox balance in mammalian cells: oxidative stress and interorganellar cross-talk. Mol Biol Cell. 2011;22:1440-1451. doi: 10.1091/mbc.E10-11-0919.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 1440-1451
-
-
Ivashchenko, O.1
Van Veldhoven, P.P.2
Brees, C.3
Ho, Y.S.4
Terlecky, S.R.5
Fransen, M.6
-
89
-
-
84884244569
-
Mitochondria are targets for peroxisome-derived oxidative stress in cultured mammalian cells
-
Wang B, Van Veldhoven PP, Brees C, Rubio N, Nordgren M, Apanasets O, Kunze M, Baes M, Agostinis P, Fransen M. Mitochondria are targets for peroxisome-derived oxidative stress in cultured mammalian cells. Free Radic Biol Med. 2013;65:882-894. doi: 10.1016/j.freeradbiomed.2013.08.173.
-
(2013)
Free Radic Biol Med
, vol.65
, pp. 882-894
-
-
Wang, B.1
Van Veldhoven, P.P.2
Brees, C.3
Rubio, N.4
Nordgren, M.5
Apanasets, O.6
Kunze, M.7
Baes, M.8
Agostinis, P.9
Fransen, M.10
-
90
-
-
77950343252
-
Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
-
Hotamisligil GS. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell. 2010;140:900-917. doi: 10.1016/j. cell.2010.02.034.
-
(2010)
Cell
, vol.140
, pp. 900-917
-
-
Hotamisligil, G.S.1
-
91
-
-
78349265743
-
Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease
-
Minamino T, Komuro I, Kitakaze M. Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease. Circ Res. 2010;107:1071-1082. doi: 10.1161/CIRCRESAHA.110.227819.
-
(2010)
Circ Res
, vol.107
, pp. 1071-1082
-
-
Minamino, T.1
Komuro, I.2
Kitakaze, M.3
-
92
-
-
84903795970
-
Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease
-
Cao SS, Kaufman RJ. Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease. Antioxid Redox Signal. 2014;21:396-413. doi: 10.1089/ars.2014.5851.
-
(2014)
Antioxid Redox Signal
, vol.21
, pp. 396-413
-
-
Cao, S.S.1
Kaufman, R.J.2
-
93
-
-
78650270477
-
Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum
-
Tavender TJ, Springate JJ, Bulleid NJ. Recycling of peroxiredoxin IV provides a novel pathway for disulphide formation in the endoplasmic reticulum. EMBO J. 2010;29:4185-4197. doi: 10.1038/emboj.2010.273.
-
(2010)
EMBO J
, vol.29
, pp. 4185-4197
-
-
Tavender, T.J.1
Springate, J.J.2
Bulleid, N.J.3
-
94
-
-
84938300316
-
Antioxidant responses and cellular adjustments to oxidative stress
-
Espinosa-Diez C, Miguel V, Mennerich D, Kietzmann T, Sánchez-Pérez P, Cadenas S, Lamas S. Antioxidant responses and cellular adjustments to oxidative stress. Redox Biol. 2015;6:183-197. doi: 10.1016/j. redox.2015.07.008.
-
(2015)
Redox Biol
, vol.6
, pp. 183-197
-
-
Espinosa-Diez, C.1
Miguel, V.2
Mennerich, D.3
Kietzmann, T.4
Sánchez-Pérez, P.5
Cadenas, S.6
Lamas, S.7
-
95
-
-
84869210796
-
Hyperactivity of the Ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response
-
Hansen HG, Schmidt JD, Søltoft CL, Ramming T, Geertz-Hansen HM, Christensen B, Sørensen ES, Juncker AS, Appenzeller-Herzog C, Ellgaard L. Hyperactivity of the Ero1α oxidase elicits endoplasmic reticulum stress but no broad antioxidant response. J Biol Chem. 2012;287:39513-39523. doi: 10.1074/jbc.M112.405050.
-
(2012)
J Biol Chem
, vol.287
, pp. 39513-39523
-
-
Hansen, H.G.1
Schmidt, J.D.2
Søltoft, C.L.3
Ramming, T.4
Geertz-Hansen, H.M.5
Christensen, B.6
Sørensen, E.S.7
Juncker, A.S.8
Appenzeller-Herzog, C.9
Ellgaard, L.10
-
96
-
-
57449092891
-
Antioxidants reduce endoplasmic reticulum stress and improve protein secretion
-
Malhotra JD, Miao H, Zhang K, Wolfson A, Pennathur S, Pipe SW, Kaufman RJ. Antioxidants reduce endoplasmic reticulum stress and improve protein secretion. Proc Natl Acad Sci USA. 2008;105:18525-18530. doi: 10.1073/pnas.0809677105.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 18525-18530
-
-
Malhotra, J.D.1
Miao, H.2
Zhang, K.3
Wolfson, A.4
Pennathur, S.5
Pipe, S.W.6
Kaufman, R.J.7
-
97
-
-
4444268690
-
Mechanisms that regulate production of reactive oxygen species by cytochrome P450
-
Zangar RC, Davydov DR, Verma S. Mechanisms that regulate production of reactive oxygen species by cytochrome P450. Toxicol Appl Pharmacol. 2004;199:316-331. doi: 10.1016/j.taap.2004.01.018.
-
(2004)
Toxicol Appl Pharmacol
, vol.199
, pp. 316-331
-
-
Zangar, R.C.1
Davydov, D.R.2
Verma, S.3
-
98
-
-
84902254569
-
Purified NADH-cytochrome b5 reductase is a novel superoxide anion source inhibited by apocynin: Sensitivity to nitric oxide and peroxynitrite
-
Samhan-Arias AK, Gutierrez-Merino C. Purified NADH-cytochrome b5 reductase is a novel superoxide anion source inhibited by apocynin: sensitivity to nitric oxide and peroxynitrite. Free Radic Biol Med. 2014;73:174-189. doi: 10.1016/j.freeradbiomed.2014.04.033.
-
(2014)
Free Radic Biol Med
, vol.73
, pp. 174-189
-
-
Samhan-Arias, A.K.1
Gutierrez-Merino, C.2
-
99
-
-
77954382142
-
Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation
-
Wu RF, Ma Z, Liu Z, Terada LS. Nox4-derived H2O2 mediates endoplasmic reticulum signaling through local Ras activation. Mol Cell Biol. 2010;30:3553-3568. doi: 10.1128/MCB.01445-09.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3553-3568
-
-
Wu, R.F.1
Ma, Z.2
Liu, Z.3
Terada, L.S.4
-
100
-
-
84929300310
-
The antioxidant machinery of the endoplasmic reticulum: Protection and signaling
-
Delaunay-Moisan A, Appenzeller-Herzog C. The antioxidant machinery of the endoplasmic reticulum: protection and signaling. Free Radic Biol Med. 2015;83:341-351. doi: 10.1016/j.freeradbiomed.2015.02.019.
-
(2015)
Free Radic Biol Med
, vol.83
, pp. 341-351
-
-
Delaunay-Moisan, A.1
Appenzeller-Herzog, C.2
-
101
-
-
84870877138
-
Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease
-
Wei PC, Hsieh YH, Su MI, Jiang X, Hsu PH, Lo WT, Weng JY, Jeng YM, Wang JM, Chen PL, Chang YC, Lee KF, Tsai MD, Shew JY, Lee WH. Loss of the oxidative stress sensor NPGPx compromises GRP78 chaperone activity and induces systemic disease. Mol Cell. 2012;48:747-759. doi: 10.1016/j.molcel.2012.10.007.
-
(2012)
Mol Cell
, vol.48
, pp. 747-759
-
-
Wei, P.C.1
Hsieh, Y.H.2
Su, M.I.3
Jiang, X.4
Hsu, P.H.5
Lo, W.T.6
Weng, J.Y.7
Jeng, Y.M.8
Wang, J.M.9
Chen, P.L.10
Chang, Y.C.11
Lee, K.F.12
Tsai, M.D.13
Shew, J.Y.14
Lee, W.H.15
-
103
-
-
84859232387
-
Ero1α regulates Ca(2+) fluxes at the endoplasmic reticulum-mitochondria interface (MAM)
-
Anelli T, Bergamelli L, Margittai E, Rimessi A, Fagioli C, Malgaroli A, Pinton P, Ripamonti M, Rizzuto R, Sitia R. Ero1α regulates Ca(2+) fluxes at the endoplasmic reticulum-mitochondria interface (MAM). Antioxid Redox Signal. 2012;16:1077-1087. doi: 10.1089/ars.2011.4004.
-
(2012)
Antioxid Redox Signal
, vol.16
, pp. 1077-1087
-
-
Anelli, T.1
Bergamelli, L.2
Margittai, E.3
Rimessi, A.4
Fagioli, C.5
Malgaroli, A.6
Pinton, P.7
Ripamonti, M.8
Rizzuto, R.9
Sitia, R.10
-
104
-
-
0033581704
-
The p66shc adaptor protein controls oxidative stress response and life span in mammals
-
Migliaccio E, Giorgio M, Mele S, Pelicci G, Reboldi P, Pandolfi PP, Lanfrancone L, Pelicci PG. The p66shc adaptor protein controls oxidative stress response and life span in mammals. Nature. 1999;402:309-313. doi: 10.1038/46311.
-
(1999)
Nature
, vol.402
, pp. 309-313
-
-
Migliaccio, E.1
Giorgio, M.2
Mele, S.3
Pelicci, G.4
Reboldi, P.5
Pandolfi, P.P.6
Lanfrancone, L.7
Pelicci, P.G.8
-
105
-
-
22744447211
-
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis
-
Giorgio M, Migliaccio E, Orsini F, Paolucci D, Moroni M, Contursi C, Pelliccia G, Luzi L, Minucci S, Marcaccio M, Pinton P, Rizzuto R, Bernardi P, Paolucci F, Pelicci PG. Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis. Cell. 2005;122:221-233. doi: 10.1016/j.cell.2005.05.011.
-
(2005)
Cell
, vol.122
, pp. 221-233
-
-
Giorgio, M.1
Migliaccio, E.2
Orsini, F.3
Paolucci, D.4
Moroni, M.5
Contursi, C.6
Pelliccia, G.7
Luzi, L.8
Minucci, S.9
Marcaccio, M.10
Pinton, P.11
Rizzuto, R.12
Bernardi, P.13
Paolucci, F.14
Pelicci, P.G.15
-
106
-
-
85025820364
-
Role of p66shc in skeletal muscle function
-
Granatiero V, Gherardi G, Vianello M, Salerno E, Zecchini E, Toniolo L, Pallafacchina G, Murgia M, Blaauw B, Rizzuto R, Mammucari C. Role of p66shc in skeletal muscle function. Sci Rep. 2017;7:6283. doi: 10.1038/s41598-017-06363-0.
-
(2017)
Sci Rep
, vol.7
, pp. 6283
-
-
Granatiero, V.1
Gherardi, G.2
Vianello, M.3
Salerno, E.4
Zecchini, E.5
Toniolo, L.6
Pallafacchina, G.7
Murgia, M.8
Blaauw, B.9
Rizzuto, R.10
Mammucari, C.11
-
107
-
-
84894284442
-
The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism
-
Soliman MA, Abdel Rahman AM, Lamming DW, Lamming DA, Birsoy K, Pawling J, Frigolet ME, Lu H, Fantus IG, Pasculescu A, Zheng Y, Sabatini DM, Dennis JW, Pawson T. The adaptor protein p66Shc inhibits mTOR-dependent anabolic metabolism. Sci Signal. 2014;7:ra17. doi: 10.1126/scisignal.2004785.
-
(2014)
Sci Signal
, vol.7
, pp. ra17
-
-
Soliman, M.A.1
Abdel Rahman, A.M.2
Lamming, D.W.3
Lamming, D.A.4
Birsoy, K.5
Pawling, J.6
Frigolet, M.E.7
Lu, H.8
Fantus, I.G.9
Pasculescu, A.10
Zheng, Y.11
Sabatini, D.M.12
Dennis, J.W.13
Pawson, T.14
-
108
-
-
78650878363
-
NF-κB, inflammation, and metabolic disease
-
Baker RG, Hayden MS, Ghosh S. NF-κB, inflammation, and metabolic disease. Cell Metab. 2011;13:11-22. doi: 10.1016/j.cmet.2010.12.008.
-
(2011)
Cell Metab
, vol.13
, pp. 11-22
-
-
Baker, R.G.1
Hayden, M.S.2
Ghosh, S.3
-
109
-
-
20044387026
-
IKK-beta links inflammation to obesity-induced insulin resistance
-
Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. IKK-beta links inflammation to obesity-induced insulin resistance. Nat Med. 2005;11:191-198. doi: 10.1038/nm1185.
-
(2005)
Nat Med
, vol.11
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
110
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, Chen H. Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. J Clin Invest. 2003;112:1821-1830. doi: 10.1172/JCI19451.
-
(2003)
J Clin Invest
, vol.112
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
111
-
-
80053539605
-
NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration
-
Mauro C, Leow SC, Anso E, Rocha S, Thotakura AK, Tornatore L, Moretti M, De Smaele E, Beg AA, Tergaonkar V, Chandel NS, Franzoso G. NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration. Nat Cell Biol. 2011;13:1272-1279. doi: 10.1038/ncb2324.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1272-1279
-
-
Mauro, C.1
Leow, S.C.2
Anso, E.3
Rocha, S.4
Thotakura, A.K.5
Tornatore, L.6
Moretti, M.7
De Smaele, E.8
Beg, A.A.9
Tergaonkar, V.10
Chandel, N.S.11
Franzoso, G.12
-
112
-
-
14044277556
-
Redox regulation of NF-kappaB activation: Distinct redox regulation between the cytoplasm and the nucleus
-
Kabe Y, Ando K, Hirao S, Yoshida M, Handa H. Redox regulation of NF-kappaB activation: distinct redox regulation between the cytoplasm and the nucleus. Antioxid Redox Signal. 2005;7:395-403. doi: 10.1089/ ars.2005.7.395.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 395-403
-
-
Kabe, Y.1
Ando, K.2
Hirao, S.3
Yoshida, M.4
Handa, H.5
-
113
-
-
0027365599
-
Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells
-
Marui N, Offermann MK, Swerlick R, Kunsch C, Rosen CA, Ahmad M, Alexander RW, Medford RM. Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells. J Clin Invest. 1993;92:1866-1874. doi: 10.1172/JCI116778.
-
(1993)
J Clin Invest
, vol.92
, pp. 1866-1874
-
-
Marui, N.1
Offermann, M.K.2
Swerlick, R.3
Kunsch, C.4
Rosen, C.A.5
Ahmad, M.6
Alexander, R.W.7
Medford, R.M.8
-
114
-
-
0345149546
-
Oxidative stress induces nf-κb nuclear translocation without degradation of iκbα
-
Canty TG, Boyle EM, Farr A, Morgan EN, Verrier ED, Pohlman TH. Oxidative stress induces nf-κb nuclear translocation without degradation of iκbα. Circulation. 1999;100:II-361-Ii-364.
-
(1999)
Circulation
, vol.100
, pp. II361-II364
-
-
Canty, T.G.1
Boyle, E.M.2
Farr, A.3
Morgan, E.N.4
Verrier, E.D.5
Pohlman, T.H.6
-
115
-
-
0037591401
-
Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: Evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase
-
Takada Y, Mukhopadhyay A, Kundu GC, Mahabeleshwar GH, Singh S, Aggarwal BB. Hydrogen peroxide activates NF-kappa B through tyrosine phosphorylation of I kappa B alpha and serine phosphorylation of p65: evidence for the involvement of I kappa B alpha kinase and Syk protein-tyrosine kinase. J Biol Chem. 2003;278:24233-24241. doi: 10.1074/ jbc.M212389200.
-
(2003)
J Biol Chem
, vol.278
, pp. 24233-24241
-
-
Takada, Y.1
Mukhopadhyay, A.2
Kundu, G.C.3
Mahabeleshwar, G.H.4
Singh, S.5
Aggarwal, B.B.6
-
116
-
-
0034655179
-
Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress
-
Schoonbroodt S, Ferreira V, Best-Belpomme M, Boelaert JR, Legrand-Poels S, Korner M, Piette J. Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress. J Immunol. 2000;164:4292-4300.
-
(2000)
J Immunol
, vol.164
, pp. 4292-4300
-
-
Schoonbroodt, S.1
Ferreira, V.2
Best-Belpomme, M.3
Boelaert, J.R.4
Legrand-Poels, S.5
Korner, M.6
Piette, J.7
-
117
-
-
84872308934
-
SIRT3 protects cardiomyocytes from oxidative stress-mediated cell death by activating NF-κB
-
Chen CJ, Fu YC, Yu W, Wang W. SIRT3 protects cardiomyocytes from oxidative stress-mediated cell death by activating NF-κB. Biochem Biophys Res Commun. 2013;430:798-803. doi: 10.1016/j.bbrc.2012.11.066.
-
(2013)
Biochem Biophys Res Commun
, vol.430
, pp. 798-803
-
-
Chen, C.J.1
Fu, Y.C.2
Yu, W.3
Wang, W.4
-
118
-
-
33845603497
-
Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase
-
Johar S, Cave AC, Narayanapanicker A, Grieve DJ, Shah AM. Aldosterone mediates angiotensin II-induced interstitial cardiac fibrosis via a Nox2-containing NADPH oxidase. FASEB J. 2006;20:1546-1548. doi: 10.1096/fj.05-4642fje.
-
(2006)
FASEB J
, vol.20
, pp. 1546-1548
-
-
Johar, S.1
Cave, A.C.2
Narayanapanicker, A.3
Grieve, D.J.4
Shah, A.M.5
-
119
-
-
33646831500
-
NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox
-
Anrather J, Racchumi G, Iadecola C. NF-kappaB regulates phagocytic NADPH oxidase by inducing the expression of gp91phox. J Biol Chem. 2006;281:5657-5667. doi: 10.1074/jbc.M506172200.
-
(2006)
J Biol Chem
, vol.281
, pp. 5657-5667
-
-
Anrather, J.1
Racchumi, G.2
Iadecola, C.3
-
120
-
-
34548424587
-
Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha
-
Gauss KA, Nelson-Overton LK, Siemsen DW, Gao Y, DeLeo FR, Quinn MT. Role of NF-kappaB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-alpha. J Leukoc Biol. 2007;82:729-741. doi: 10.1189/jlb.1206735.
-
(2007)
J Leukoc Biol
, vol.82
, pp. 729-741
-
-
Gauss, K.A.1
Nelson-Overton, L.K.2
Siemsen, D.W.3
Gao, Y.4
DeLeo, F.R.5
Quinn, M.T.6
-
121
-
-
33645242238
-
Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes
-
Li Q, Harraz MM, Zhou W, Zhang LN, Ding W, Zhang Y, Eggleston T, Yeaman C, Banfi B, Engelhardt JF. Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes. Mol Cell Biol. 2006;26:140-154. doi: 10.1128/ MCB.26.1.140-154.2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 140-154
-
-
Li, Q.1
Harraz, M.M.2
Zhou, W.3
Zhang, L.N.4
Ding, W.5
Zhang, Y.6
Eggleston, T.7
Yeaman, C.8
Banfi, B.9
Engelhardt, J.F.10
-
122
-
-
4644350365
-
Cutting edge: Direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa B
-
Park HS, Jung HY, Park EY, Kim J, Lee WJ, Bae YS. Cutting edge: direct interaction of TLR4 with NAD(P)H oxidase 4 isozyme is essential for lipopolysaccharide-induced production of reactive oxygen species and activation of NF-kappa B. J Immunol. 2004;173:3589-3593.
-
(2004)
J Immunol
, vol.173
, pp. 3589-3593
-
-
Park, H.S.1
Jung, H.Y.2
Park, E.Y.3
Kim, J.4
Lee, W.J.5
Bae, Y.S.6
-
123
-
-
33750523632
-
NF-kappaB activation by reactive oxygen species: Fifteen years later
-
Gloire G, Legrand-Poels S, Piette J. NF-kappaB activation by reactive oxygen species: fifteen years later. Biochem Pharmacol. 2006;72:1493-1505. doi: 10.1016/j.bcp.2006.04.011.
-
(2006)
Biochem Pharmacol
, vol.72
, pp. 1493-1505
-
-
Gloire, G.1
Legrand-Poels, S.2
Piette, J.3
-
124
-
-
10744220574
-
Oscillatory shear stress stimulates endothelial production of O2- From p47phox-de-pendent NAD(P)H oxidases, leading to monocyte adhesion
-
Hwang J, Saha A, Boo YC, Sorescu GP, McNally JS, Holland SM, Dikalov S, Giddens DP, Griendling KK, Harrison DG, Jo H. Oscillatory shear stress stimulates endothelial production of O2- from p47phox-de-pendent NAD(P)H oxidases, leading to monocyte adhesion. J Biol Chem. 2003;278:47291-47298. doi: 10.1074/jbc.M305150200.
-
(2003)
J Biol Chem
, vol.278
, pp. 47291-47298
-
-
Hwang, J.1
Saha, A.2
Boo, Y.C.3
Sorescu, G.P.4
McNally, J.S.5
Holland, S.M.6
Dikalov, S.7
Giddens, D.P.8
Griendling, K.K.9
Harrison, D.G.10
Jo, H.11
-
125
-
-
33846320457
-
Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-kappaB in endothelial cells
-
Mohan S, Koyoma K, Thangasamy A, Nakano H, Glickman RD, Mohan N. Low shear stress preferentially enhances IKK activity through selective sources of ROS for persistent activation of NF-kappaB in endothelial cells. Am J Physiol Cell Physiol. 2007;292:C362-C371. doi: 10.1152/ ajpcell.00535.2005.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
, pp. C362-C371
-
-
Mohan, S.1
Koyoma, K.2
Thangasamy, A.3
Nakano, H.4
Glickman, R.D.5
Mohan, N.6
-
126
-
-
6344283050
-
Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase
-
Sorescu GP, Song H, Tressel SL, Hwang J, Dikalov S, Smith DA, Boyd NL, Platt MO, Lassègue B, Griendling KK, Jo H. Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase. Circ Res. 2004;95:773-779. doi: 10.1161/01.RES.0000145728.22878.45.
-
(2004)
Circ Res
, vol.95
, pp. 773-779
-
-
Sorescu, G.P.1
Song, H.2
Tressel, S.L.3
Hwang, J.4
Dikalov, S.5
Smith, D.A.6
Boyd, N.L.7
Platt, M.O.8
Lassègue, B.9
Griendling, K.K.10
Jo, H.11
-
127
-
-
53249142641
-
P21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow
-
Orr AW, Hahn C, Blackman BR, Schwartz MA. p21-activated kinase signaling regulates oxidant-dependent NF-kappa B activation by flow. Circ Res. 2008;103:671-679. doi: 10.1161/CIRCRESAHA.108.182097.
-
(2008)
Circ Res
, vol.103
, pp. 671-679
-
-
Orr, A.W.1
Hahn, C.2
Blackman, B.R.3
Schwartz, M.A.4
-
128
-
-
35649012722
-
G protein-coupled receptor Ca2+-linked mitochondrial reactive oxygen species are essential for endothelial/ leukocyte adherence
-
Hawkins BJ, Solt LA, Chowdhury I, Kazi AS, Abid MR, Aird WC, May MJ, Foskett JK, Madesh M. G protein-coupled receptor Ca2+-linked mitochondrial reactive oxygen species are essential for endothelial/ leukocyte adherence. Mol Cell Biol. 2007;27:7582-7593. doi: 10.1128/ MCB.00493-07.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 7582-7593
-
-
Hawkins, B.J.1
Solt, L.A.2
Chowdhury, I.3
Kazi, A.S.4
Abid, M.R.5
Aird, W.C.6
May, M.J.7
Foskett, J.K.8
Madesh, M.9
-
129
-
-
84964649259
-
Mitochondrial reactive oxygen species mediate lysophosphatidylcholine-induced endothelial cell activation
-
Li X, Fang P, Li Y, et al. Mitochondrial reactive oxygen species mediate lysophosphatidylcholine-induced endothelial cell activation. Arterioscler Thromb Vasc Biol. 2016;36:1090-1100. doi: 10.1161/ ATVBAHA.115.306964.
-
(2016)
Arterioscler Thromb Vasc Biol
, vol.36
, pp. 1090-1100
-
-
Li, X.1
Fang, P.2
Li, Y.3
-
130
-
-
34547178903
-
Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries
-
Ungvari Z, Orosz Z, Labinskyy N, Rivera A, Xiangmin Z, Smith K, Csiszar A. Increased mitochondrial H2O2 production promotes endothelial NF-kappaB activation in aged rat arteries. Am J Physiol Heart Circ Physiol. 2007;293:H37-H47. doi: 10.1152/ajpheart.01346.2006.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.293
, pp. H37-H47
-
-
Ungvari, Z.1
Orosz, Z.2
Labinskyy, N.3
Rivera, A.4
Xiangmin, Z.5
Smith, K.6
Csiszar, A.7
-
131
-
-
0036121596
-
Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia
-
Pearlstein DP, Ali MH, Mungai PT, Hynes KL, Gewertz BL, Schumacker PT. Role of mitochondrial oxidant generation in endothelial cell responses to hypoxia. Arterioscler Thromb Vasc Biol. 2002;22:566-573.
-
(2002)
Arterioscler Thromb Vasc Biol
, vol.22
, pp. 566-573
-
-
Pearlstein, D.P.1
Ali, M.H.2
Mungai, P.T.3
Hynes, K.L.4
Gewertz, B.L.5
Schumacker, P.T.6
-
132
-
-
85015769728
-
Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions
-
Zhang C, Jiang H, Wang P, Liu H, Sun X. Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions. Sci Rep. 2017;7:44708. doi: 10.1038/srep44708.
-
(2017)
Sci Rep
, vol.7
, pp. 44708
-
-
Zhang, C.1
Jiang, H.2
Wang, P.3
Liu, H.4
Sun, X.5
-
133
-
-
84990845578
-
Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages
-
Mills EL, Kelly B, Logan A, et al. Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages. Cell. 2016;167:457.e13-470.e13. doi: 10.1016/j.cell.2016.08.064.
-
(2016)
Cell
, vol.167
, pp. 457e13-470e13
-
-
Mills, E.L.1
Kelly, B.2
Logan, A.3
-
134
-
-
84876285741
-
Succinate is an inflammatory signal that induces IL-1β through HIF-1α
-
Tannahill GM, Curtis AM, Adamik J, et al. Succinate is an inflammatory signal that induces IL-1β through HIF-1α. Nature. 2013;496:238-242. doi: 10.1038/nature11986.
-
(2013)
Nature
, vol.496
, pp. 238-242
-
-
Tannahill, G.M.1
Curtis, A.M.2
Adamik, J.3
-
135
-
-
0037423948
-
HIF-1alpha is essential for myeloid cell-mediated inflammation
-
Cramer T, Yamanishi Y, Clausen BE, Förster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS. HIF-1alpha is essential for myeloid cell-mediated inflammation. Cell. 2003;112:645-657.
-
(2003)
Cell
, vol.112
, pp. 645-657
-
-
Cramer, T.1
Yamanishi, Y.2
Clausen, B.E.3
Förster, I.4
Pawlinski, R.5
Mackman, N.6
Haase, V.H.7
Jaenisch, R.8
Corr, M.9
Nizet, V.10
Firestein, G.S.11
Gerber, H.P.12
Ferrara, N.13
Johnson, R.S.14
-
136
-
-
84995751273
-
Mechanism and regulation of NLRP3 inflammasome activation
-
He Y, Hara H, Núñez G. Mechanism and regulation of NLRP3 inflammasome activation. Trends Biochem Sci. 2016;41:1012-1021. doi: 10.1016/j.tibs.2016.09.002.
-
(2016)
Trends Biochem Sci
, vol.41
, pp. 1012-1021
-
-
He, Y.1
Hara, H.2
Núñez, G.3
-
138
-
-
84887446052
-
Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation
-
Heid ME, Keyel PA, Kamga C, Shiva S, Watkins SC, Salter RD. Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation. J Immunol. 2013;191:5230-5238. doi: 10.4049/jimmunol.1301490.
-
(2013)
J Immunol
, vol.191
, pp. 5230-5238
-
-
Heid, M.E.1
Keyel, P.A.2
Kamga, C.3
Shiva, S.4
Watkins, S.C.5
Salter, R.D.6
-
139
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
Zhou R, Yazdi AS, Menu P, Tschopp J. A role for mitochondria in NLRP3 inflammasome activation. Nature. 2011;469:221-225. doi: 10.1038/ nature09663.
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
-
140
-
-
84959917649
-
Molecular mechanisms regulating NLRP3 inflammasome activation
-
Jo EK, Kim JK, Shin DM, Sasakawa C. Molecular mechanisms regulating NLRP3 inflammasome activation. Cell Mol Immunol. 2016;13:148-159. doi: 10.1038/cmi.2015.95.
-
(2016)
Cell Mol Immunol
, vol.13
, pp. 148-159
-
-
Jo, E.K.1
Kim, J.K.2
Shin, D.M.3
Sasakawa, C.4
-
141
-
-
77649241827
-
IL-1beta processing in host defense: Beyond the in-flammasomes
-
Netea MG, Simon A, van de Veerdonk F, Kullberg BJ, Van der Meer JW, Joosten LA. IL-1beta processing in host defense: beyond the in-flammasomes. PLoS Pathog. 2010;6:e1000661. doi: 10.1371/journal. ppat.1000661.
-
(2010)
PLoS Pathog
, vol.6
, pp. e1000661
-
-
Netea, M.G.1
Simon, A.2
Van De Veerdonk, F.3
Kullberg, B.J.4
Van Der Meer, J.W.5
Joosten, L.A.6
-
142
-
-
75649096002
-
Thioredoxin-interacting protein links oxidative stress to inflammasome activation
-
Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J. Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol. 2010;11:136-140. doi: 10.1038/ni.1831.
-
(2010)
Nat Immunol
, vol.11
, pp. 136-140
-
-
Zhou, R.1
Tardivel, A.2
Thorens, B.3
Choi, I.4
Tschopp, J.5
-
143
-
-
84874918845
-
Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells
-
Shah A, Xia L, Goldberg H, Lee KW, Quaggin SE, Fantus IG. Thioredoxin-interacting protein mediates high glucose-induced reactive oxygen species generation by mitochondria and the NADPH oxidase, Nox4, in mesangial cells. J Biol Chem. 2013;288:6835-6848. doi: 10.1074/jbc.M112.419101.
-
(2013)
J Biol Chem
, vol.288
, pp. 6835-6848
-
-
Shah, A.1
Xia, L.2
Goldberg, H.3
Lee, K.W.4
Quaggin, S.E.5
Fantus, I.G.6
-
144
-
-
84864682160
-
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress
-
Lerner AG, Upton JP, Praveen PV, et al. IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress. Cell Metab. 2012;16:250-264. doi: 10.1016/j.cmet.2012.07.007.
-
(2012)
Cell Metab
, vol.16
, pp. 250-264
-
-
Lerner, A.G.1
Upton, J.P.2
Praveen, P.V.3
-
145
-
-
84941652089
-
Endoplasmic reticulum stress activates the inflammasome via NLRP3- And caspase-2-driven mitochondrial damage
-
Bronner DN, Abuaita BH, Chen X, Fitzgerald KA, Nuñez G, He Y, Yin XM, O'Riordan MX. Endoplasmic reticulum stress activates the inflammasome via NLRP3- and caspase-2-driven mitochondrial damage. Immunity. 2015;43:451-462. doi: 10.1016/j.immuni.2015.08.008.
-
(2015)
Immunity
, vol.43
, pp. 451-462
-
-
Bronner, D.N.1
Abuaita, B.H.2
Chen, X.3
Fitzgerald, K.A.4
Nuñez, G.5
He, Y.6
Yin, X.M.7
O'Riordan, M.X.8
-
146
-
-
0037115158
-
Reactive oxygen species and cell signaling: Respiratory burst in macrophage signaling
-
Forman HJ, Torres M. Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling. Am J Respir Crit Care Med. 2002;166:S4-S8. doi: 10.1164/rccm.2206007.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. S4-S8
-
-
Forman, H.J.1
Torres, M.2
-
147
-
-
84911878872
-
NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice
-
Kigawa Y, Miyazaki T, Lei XF, Nakamachi T, Oguchi T, Kim-Kaneyama JR, Taniyama M, Tsunawaki S, Shioda S, Miyazaki A. NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice. Arterioscler Thromb Vasc Biol. 2014;34:2413-2420. doi: 10.1161/ATVBAHA.114.303086.
-
(2014)
Arterioscler Thromb Vasc Biol
, vol.34
, pp. 2413-2420
-
-
Kigawa, Y.1
Miyazaki, T.2
Lei, X.F.3
Nakamachi, T.4
Oguchi, T.5
Kim-Kaneyama, J.R.6
Taniyama, M.7
Tsunawaki, S.8
Shioda, S.9
Miyazaki, A.10
-
148
-
-
77956612015
-
NADPH oxidase limits innate immune responses in the lungs in mice
-
Segal BH, Han W, Bushey JJ, et al. NADPH oxidase limits innate immune responses in the lungs in mice. PLoS One. 2010;5:e9631. doi: 10.1371/journal.pone.0009631.
-
(2010)
PLoS One
, vol.5
, pp. e9631
-
-
Segal, B.H.1
Han, W.2
Bushey, J.J.3
-
149
-
-
84934287492
-
Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins
-
Martinez J, Malireddi RK, Lu Q, Cunha LD, Pelletier S, Gingras S, Orchard R, Guan JL, Tan H, Peng J, Kanneganti TD, Virgin HW, Green DR. Molecular characterization of LC3-associated phagocytosis reveals distinct roles for Rubicon, NOX2 and autophagy proteins. Nat Cell Biol. 2015;17:893-906. doi: 10.1038/ncb3192.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 893-906
-
-
Martinez, J.1
Malireddi, R.K.2
Lu, Q.3
Cunha, L.D.4
Pelletier, S.5
Gingras, S.6
Orchard, R.7
Guan, J.L.8
Tan, H.9
Peng, J.10
Kanneganti, T.D.11
Virgin, H.W.12
Green, D.R.13
-
150
-
-
79955532516
-
TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
-
West AP, Brodsky IE, Rahner C, Woo DK, Erdjument-Bromage H, Tempst P, Walsh MC, Choi Y, Shadel GS, Ghosh S. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature. 2011;472:476-480. doi: 10.1038/nature09973.
-
(2011)
Nature
, vol.472
, pp. 476-480
-
-
West, A.P.1
Brodsky, I.E.2
Rahner, C.3
Woo, D.K.4
Erdjument-Bromage, H.5
Tempst, P.6
Walsh, M.C.7
Choi, Y.8
Shadel, G.S.9
Ghosh, S.10
-
151
-
-
85029682530
-
Mitochondrial fission promotes the continued clearance of apoptotic cells by macrophages
-
Wang Y, Subramanian M, Yurdagul A Jr, Barbosa-Lorenzi VC, Cai B, de Juan-Sanz J, Ryan TA, Nomura M, Maxfield FR, Tabas I. Mitochondrial fission promotes the continued clearance of apoptotic cells by macrophages. Cell. 2017;171:331.e22-345.e22. doi: 10.1016/j. cell.2017.08.041.
-
(2017)
Cell
, vol.171
, pp. 331e22-345e22
-
-
Wang, Y.1
Subramanian, M.2
Jr, Y.A.3
Barbosa-Lorenzi, V.C.4
Cai, B.5
De Juan-Sanz, J.6
Ryan, T.A.7
Nomura, M.8
Maxfield, F.R.9
Tabas, I.10
-
152
-
-
84899657232
-
Dynamin related protein 1-dependent mitochondrial fission regulates oxidative signalling in T cells
-
Röth D, Krammer PH, Gülow K. Dynamin related protein 1-dependent mitochondrial fission regulates oxidative signalling in T cells. FEBS Lett. 2014;588:1749-1754. doi: 10.1016/j.febslet.2014.03.029.
-
(2014)
FEBS Lett
, vol.588
, pp. 1749-1754
-
-
Röth, D.1
Krammer, P.H.2
Gülow, K.3
-
153
-
-
84976478216
-
Mitochondrial dynamics controls T cell fate through metabolic programming
-
Buck MD, O'Sullivan D, Klein Geltink RI, et al. Mitochondrial dynamics controls T cell fate through metabolic programming. Cell. 2016;166:63-76. doi: 10.1016/j.cell.2016.05.035.
-
(2016)
Cell
, vol.166
, pp. 63-76
-
-
Buck, M.D.1
O'Sullivan, D.2
Klein Geltink, R.I.3
-
154
-
-
33846872571
-
A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation
-
Sather S, Kenyon KD, Lefkowitz JB, Liang X, Varnum BC, Henson PM, Graham DK. A soluble form of the Mer receptor tyrosine kinase inhibits macrophage clearance of apoptotic cells and platelet aggregation. Blood. 2007;109:1026-1033. doi: 10.1182/blood-2006-05-021634.
-
(2007)
Blood
, vol.109
, pp. 1026-1033
-
-
Sather, S.1
Kenyon, K.D.2
Lefkowitz, J.B.3
Liang, X.4
Varnum, B.C.5
Henson, P.M.6
Graham, D.K.7
-
155
-
-
80053030745
-
Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK)
-
Thorp E, Vaisar T, Subramanian M, Mautner L, Blobel C, Tabas I. Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 mitogen-activated protein kinase (MAPK). J Biol Chem. 2011;286:33335-33344. doi: 10.1074/jbc.M111.263020.
-
(2011)
J Biol Chem
, vol.286
, pp. 33335-33344
-
-
Thorp, E.1
Vaisar, T.2
Subramanian, M.3
Mautner, L.4
Blobel, C.5
Tabas, I.6
-
156
-
-
84883738441
-
Mitochondria and AMP-activated protein kinase-dependent mechanism of efferocytosis
-
Jiang S, Park DW, Stigler WS, Creighton J, Ravi S, Darley-Usmar V, Zmijewski JW. Mitochondria and AMP-activated protein kinase-dependent mechanism of efferocytosis. J Biol Chem. 2013;288:26013-26026. doi: 10.1074/jbc.M113.489468.
-
(2013)
J Biol Chem
, vol.288
, pp. 26013-26026
-
-
Jiang, S.1
Park, D.W.2
Stigler, W.S.3
Creighton, J.4
Ravi, S.5
Darley-Usmar, V.6
Zmijewski, J.W.7
-
157
-
-
34250205155
-
TNF-alpha inhibits macrophage clearance of apoptotic cells via cytosolic phospholipase A2 and oxidant-dependent mechanisms
-
McPhillips K, Janssen WJ, Ghosh M, Byrne A, Gardai S, Remigio L, Bratton DL, Kang JL, Henson P. TNF-alpha inhibits macrophage clearance of apoptotic cells via cytosolic phospholipase A2 and oxidant-dependent mechanisms. J Immunol. 2007;178:8117-8126.
-
(2007)
J Immunol
, vol.178
, pp. 8117-8126
-
-
McPhillips, K.1
Janssen, W.J.2
Ghosh, M.3
Byrne, A.4
Gardai, S.5
Remigio, L.6
Bratton, D.L.7
Kang, J.L.8
Henson, P.9
-
158
-
-
9144219652
-
A lipid peroxidation-derived inflammatory mediator: Identification of 4-hy-droxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages
-
Kumagai T, Matsukawa N, Kaneko Y, Kusumi Y, Mitsumata M, Uchida K. A lipid peroxidation-derived inflammatory mediator: identification of 4-hy-droxy-2-nonenal as a potential inducer of cyclooxygenase-2 in macrophages. J Biol Chem. 2004;279:48389-48396. doi: 10.1074/jbc.M409935200.
-
(2004)
J Biol Chem
, vol.279
, pp. 48389-48396
-
-
Kumagai, T.1
Matsukawa, N.2
Kaneko, Y.3
Kusumi, Y.4
Mitsumata, M.5
Uchida, K.6
-
159
-
-
84877266601
-
Regulation of NF-κB-induced inflammatory signaling by lipid peroxidation-derived aldehydes
-
Yadav UC, Ramana KV. Regulation of NF-κB-induced inflammatory signaling by lipid peroxidation-derived aldehydes. Oxid Med Cell Longev. 2013;2013:690545. doi: 10.1155/2013/690545.
-
(2013)
Oxid Med Cell Longev
, vol.2013
, pp. 690545
-
-
Yadav, U.C.1
Ramana, K.V.2
-
160
-
-
1642340671
-
Regulation of inflammatory responses by oxidized phospholipids: Structure-function relationships
-
Furnkranz A, Leitinger N. Regulation of inflammatory responses by oxidized phospholipids: structure-function relationships. Curr Pharm Des. 2004;10:915-921.
-
(2004)
Curr Pharm Des
, vol.10
, pp. 915-921
-
-
Furnkranz, A.1
Leitinger, N.2
-
161
-
-
85008622650
-
Contribution of the HNE-immunohistochemistry to modern pathological concepts of major human diseases
-
Zarkovic K, Jakovcevic A, Zarkovic N. Contribution of the HNE-immunohistochemistry to modern pathological concepts of major human diseases. Free Radic Biol Med. 2017;111:110-126. doi: 10.1016/j. freeradbiomed.2016.12.009.
-
(2017)
Free Radic Biol Med
, vol.111
, pp. 110-126
-
-
Zarkovic, K.1
Jakovcevic, A.2
Zarkovic, N.3
-
162
-
-
21444445056
-
A role for oxidized phospholipids in atherosclerosis
-
Berliner JA, Watson AD. A role for oxidized phospholipids in atherosclerosis. N Engl J Med. 2005;353:9-11. doi: 10.1056/NEJMp058118.
-
(2005)
N Engl J Med
, vol.353
, pp. 9-11
-
-
Berliner, J.A.1
Watson, A.D.2
-
163
-
-
0027170699
-
Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine mono-phosphate
-
Parhami F, Fang ZT, Fogelman AM, Andalibi A, Territo MC, Berliner JA. Minimally modified low density lipoprotein-induced inflammatory responses in endothelial cells are mediated by cyclic adenosine mono-phosphate. J Clin Invest. 1993;92:471-478. doi: 10.1172/JCI116590.
-
(1993)
J Clin Invest
, vol.92
, pp. 471-478
-
-
Parhami, F.1
Fang, Z.T.2
Fogelman, A.M.3
Andalibi, A.4
Territo, M.C.5
Berliner, J.A.6
-
164
-
-
84981276527
-
Oxidized phospholipids on lipoprotein(a) elicit arterial wall inflammation and an inflammatory monocyte response in humans
-
van der Valk FM, Bekkering S, Kroon J, et al. Oxidized phospholipids on lipoprotein(a) elicit arterial wall inflammation and an inflammatory monocyte response in humans. Circulation. 2016;134:611-624.
-
(2016)
Circulation
, vol.134
, pp. 611-624
-
-
Van Der Valk, F.M.1
Bekkering, S.2
Kroon, J.3
-
165
-
-
84901917562
-
Lipid peroxidation: Production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal
-
Ayala A, Muñoz MF, Argüelles S. Lipid peroxidation: production, metabolism, and signaling mechanisms of malondialdehyde and 4-hydroxy-2-nonenal. Oxid Med Cell Longev. 2014;2014:360438.
-
(2014)
Oxid Med Cell Longev
, vol.2014
, pp. 360438
-
-
Ayala, A.1
Muñoz, M.F.2
Argüelles, S.3
-
166
-
-
1642282035
-
Inhibition of LPS- And CpG DNA-induced TNF-alpha response by oxidized phospholipids
-
Ma Z, Li J, Yang L, Mu Y, Xie W, Pitt B, Li S. Inhibition of LPS- and CpG DNA-induced TNF-alpha response by oxidized phospholipids. Am J Physiol Lung Cell Mol Physiol. 2004;286:L808-L816. doi: 10.1152/ ajplung.00220.2003.
-
(2004)
Am J Physiol Lung Cell Mol Physiol
, vol.286
, pp. L808-L816
-
-
Ma, Z.1
Li, J.2
Yang, L.3
Mu, Y.4
Xie, W.5
Pitt, B.6
Li, S.7
-
167
-
-
85013444378
-
The effect of oxidized phospholipids on phenotypic polarization and function of macrophages
-
Serbulea V, DeWeese D, Leitinger N. The effect of oxidized phospholipids on phenotypic polarization and function of macrophages. Free Radic Biol Med. 2017;111:156-168. doi: 10.1016/j.freeradbiomed.2017.02.035.
-
(2017)
Free Radic Biol Med
, vol.111
, pp. 156-168
-
-
Serbulea, V.1
DeWeese, D.2
Leitinger, N.3
-
168
-
-
85044648091
-
Nrf2 regulates endothelial glycolysis and proliferation with MIR-93 and mediates the effects of oxidized phospholipids on endothelial activation
-
Kuosmanen SM, Kansanen E, Kaikkonen MU, Sihvola V, Pulkkinen K, Jyrkkänen H-K, Tuoresmäki P, Hartikainen J, Hippeläinen M, Kokki H, Tavi P, Heikkinen S, Levonen A-L. Nrf2 regulates endothelial glycolysis and proliferation with mir-93 and mediates the effects of oxidized phospholipids on endothelial activation. Nucleic Acids Res. 2018;46:1124-1138.
-
(2018)
Nucleic Acids Res
, vol.46
, pp. 1124-1138
-
-
Kuosmanen, S.M.1
Kansanen, E.2
Kaikkonen, M.U.3
Sihvola, V.4
Pulkkinen, K.5
Jyrkkänen, H.-K.6
Tuoresmäki, P.7
Hartikainen, J.8
Hippeläinen, M.9
Kokki, H.10
Tavi, P.11
Heikkinen, S.12
Levonen, A.-L.13
-
169
-
-
84862791715
-
Macrophage autophagy plays a protective role in advanced atherosclerosis
-
Liao X, Sluimer JC, Wang Y, Subramanian M, Brown K, Pattison JS, Robbins J, Martinez J, Tabas I. Macrophage autophagy plays a protective role in advanced atherosclerosis. Cell Metab. 2012;15:545-553. doi: 10.1016/j.cmet.2012.01.022.
-
(2012)
Cell Metab
, vol.15
, pp. 545-553
-
-
Liao, X.1
Sluimer, J.C.2
Wang, Y.3
Subramanian, M.4
Brown, K.5
Pattison, J.S.6
Robbins, J.7
Martinez, J.8
Tabas, I.9
-
170
-
-
84878772042
-
Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response
-
Haberzettl P, Hill BG. Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response. Redox Biol. 2013;1:56-64. doi: 10.1016/j.redox.2012.10.003.
-
(2013)
Redox Biol
, vol.1
, pp. 56-64
-
-
Haberzettl, P.1
Hill, B.G.2
-
171
-
-
84856464242
-
Mitochondria as a source and target of lipid peroxidation products in healthy and diseased heart
-
Anderson EJ, Katunga LA, Willis MS. Mitochondria as a source and target of lipid peroxidation products in healthy and diseased heart. Clin Exp Pharmacol Physiol. 2012;39:179-193. doi: 10.1111/j.1440-1681.2011.05641.x.
-
(2012)
Clin Exp Pharmacol Physiol
, vol.39
, pp. 179-193
-
-
Anderson, E.J.1
Katunga, L.A.2
Willis, M.S.3
-
172
-
-
84938072487
-
Autophagy at the crossroads of catabolism and anabolism
-
Kaur J, Debnath J. Autophagy at the crossroads of catabolism and anabolism. Nat Rev Mol Cell Biol. 2015;16:461-472. doi: 10.1038/nrm4024.
-
(2015)
Nat Rev Mol Cell Biol
, vol.16
, pp. 461-472
-
-
Kaur, J.1
Debnath, J.2
-
173
-
-
37649005234
-
Autophagy in the pathogenesis of disease
-
Levine B, Kroemer G. Autophagy in the pathogenesis of disease. Cell. 2008;132:27-42. doi: 10.1016/j.cell.2007.12.018.
-
(2008)
Cell
, vol.132
, pp. 27-42
-
-
Levine, B.1
Kroemer, G.2
-
174
-
-
84973633815
-
Mammalian autophagy: How does it work?
-
Bento CF, Renna M, Ghislat G, Puri C, Ashkenazi A, Vicinanza M, Menzies FM, Rubinsztein DC. Mammalian autophagy: how does it work? Annu Rev Biochem. 2016;85:685-713. doi: 10.1146/ annurev-biochem-060815-014556.
-
(2016)
Annu Rev Biochem
, vol.85
, pp. 685-713
-
-
Bento, C.F.1
Renna, M.2
Ghislat, G.3
Puri, C.4
Ashkenazi, A.5
Vicinanza, M.6
Menzies, F.M.7
Rubinsztein, D.C.8
-
175
-
-
78650890352
-
Regulation of autophagy by ROS: Physiology and pathology
-
Scherz-Shouval R, Elazar Z. Regulation of autophagy by ROS: physiology and pathology. Trends Biochem Sci. 2011;36:30-38. doi: 10.1016/j. tibs.2010.07.007.
-
(2011)
Trends Biochem Sci
, vol.36
, pp. 30-38
-
-
Scherz-Shouval, R.1
Elazar, Z.2
-
176
-
-
6344275803
-
Activation of chaperone-mediated autophagy during oxidative stress
-
Kiffin R, Christian C, Knecht E, Cuervo AM. Activation of chaperone-mediated autophagy during oxidative stress. Mol Biol Cell. 2004;15:4829-4840. doi: 10.1091/mbc.E04-06-0477.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 4829-4840
-
-
Kiffin, R.1
Christian, C.2
Knecht, E.3
Cuervo, A.M.4
-
177
-
-
34247186472
-
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
-
Scherz-Shouval R, Shvets E, Fass E, Shorer H, Gil L, Elazar Z. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J. 2007;26:1749-1760. doi: 10.1038/ sj.emboj.7601623.
-
(2007)
EMBO J
, vol.26
, pp. 1749-1760
-
-
Scherz-Shouval, R.1
Shvets, E.2
Fass, E.3
Shorer, H.4
Gil, L.5
Elazar, Z.6
-
178
-
-
0043173825
-
Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells
-
Gómez-Santos C, Ferrer I, Santidrián AF, Barrachina M, Gil J, Ambrosio S. Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells. J Neurosci Res. 2003;73:341-350. doi: 10.1002/jnr.10663.
-
(2003)
J Neurosci Res
, vol.73
, pp. 341-350
-
-
Gómez-Santos, C.1
Ferrer, I.2
Santidrián, A.F.3
Barrachina, M.4
Gil, J.5
Ambrosio, S.6
-
179
-
-
34447132925
-
Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells
-
Kim EH, Sohn S, Kwon HJ, Kim SU, Kim MJ, Lee SJ, Choi KS. Sodium selenite induces superoxide-mediated mitochondrial damage and subsequent autophagic cell death in malignant glioma cells. Cancer Res. 2007;67:6314-6324. doi: 10.1158/0008-5472.CAN-06-4217.
-
(2007)
Cancer Res
, vol.67
, pp. 6314-6324
-
-
Kim, E.H.1
Sohn, S.2
Kwon, H.J.3
Kim, S.U.4
Kim, M.J.5
Lee, S.J.6
Choi, K.S.7
-
180
-
-
33750071414
-
NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy
-
Djavaheri-Mergny M, Amelotti M, Mathieu J, Besançon F, Bauvy C, Souquère S, Pierron G, Codogno P. NF-kappaB activation represses tumor necrosis factor-alpha-induced autophagy. J Biol Chem. 2006;281:30373-30382. doi: 10.1074/jbc.M602097200.
-
(2006)
J Biol Chem
, vol.281
, pp. 30373-30382
-
-
Djavaheri-Mergny, M.1
Amelotti, M.2
Mathieu, J.3
Besançon, F.4
Bauvy, C.5
Souquère, S.6
Pierron, G.7
Codogno, P.8
-
181
-
-
61949346360
-
LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection
-
Yuan H, Perry CN, Huang C, Iwai-Kanai E, Carreira RS, Glembotski CC, Gottlieb RA. LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. Am J Physiol Heart Circ Physiol. 2009;296:H470-H479. doi: 10.1152/ ajpheart.01051.2008.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
, pp. H470-H479
-
-
Yuan, H.1
Perry, C.N.2
Huang, C.3
Iwai-Kanai, E.4
Carreira, R.S.5
Glembotski, C.C.6
Gottlieb, R.A.7
-
182
-
-
77749233738
-
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
-
Alexander A, Cai SL, Kim J, Nanez A, Sahin M, MacLean KH, Inoki K, Guan KL, Shen J, Person MD, Kusewitt D, Mills GB, Kastan MB, Walker CL. ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS. Proc Natl Acad Sci USA. 2010;107:4153-4158.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4153-4158
-
-
Alexander, A.1
Cai, S.L.2
Kim, J.3
Nanez, A.4
Sahin, M.5
MacLean, K.H.6
Inoki, K.7
Guan, K.L.8
Shen, J.9
Person, M.D.10
Kusewitt, D.11
Mills, G.B.12
Kastan, M.B.13
Walker, C.L.14
-
183
-
-
84858782079
-
AMPK: A nutrient and energy sensor that maintains energy homeostasis
-
Hardie DG, Ross FA, Hawley SA. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol. 2012;13:251-262. doi: 10.1038/nrm3311.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
184
-
-
67549084381
-
Superoxide is the major reactive oxygen species regulating autophagy
-
Chen Y, Azad MB, Gibson SB. Superoxide is the major reactive oxygen species regulating autophagy. Cell Death Differ. 2009;16:1040-1052. doi: 10.1038/cdd.2009.49.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1040-1052
-
-
Chen, Y.1
Azad, M.B.2
Gibson, S.B.3
-
185
-
-
84882675717
-
Immobilization-induced activation of key proteolytic systems in skeletal muscles is prevented by a mitochondria-targeted antioxidant
-
Talbert EE, Smuder AJ, Min K, Kwon OS, Szeto HH, Powers SK. Immobilization-induced activation of key proteolytic systems in skeletal muscles is prevented by a mitochondria-targeted antioxidant. J Appl Physiol (1985). 2013;115:529-538. doi: 10.1152/ japplphysiol.00471.2013.
-
(2013)
J Appl Physiol (1985)
, vol.115
, pp. 529-538
-
-
Talbert, E.E.1
Smuder, A.J.2
Min, K.3
Kwon, O.S.4
Szeto, H.H.5
Powers, S.K.6
-
186
-
-
0034596947
-
Reactive oxygen species (ROS)-induced ROS release: A new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes
-
Zorov DB, Filburn CR, Klotz LO, Zweier JL, Sollott SJ. Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J Exp Med. 2000;192:1001-1014.
-
(2000)
J Exp Med
, vol.192
, pp. 1001-1014
-
-
Zorov, D.B.1
Filburn, C.R.2
Klotz, L.O.3
Zweier, J.L.4
Sollott, S.J.5
-
187
-
-
84903649897
-
Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release
-
Zorov DB, Juhaszova M, Sollott SJ. Mitochondrial reactive oxygen species (ROS) and ROS-induced ROS release. Physiol Rev. 2014;94:909-950. doi: 10.1152/physrev.00026.2013.
-
(2014)
Physiol Rev
, vol.94
, pp. 909-950
-
-
Zorov, D.B.1
Juhaszova, M.2
Sollott, S.J.3
-
188
-
-
16844366524
-
Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging
-
Lemasters JJ. Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging. Rejuvenation Res. 2005;8:3-5. doi: 10.1089/rej.2005.8.3.
-
(2005)
Rejuvenation Res
, vol.8
, pp. 3-5
-
-
Lemasters, J.J.1
-
189
-
-
85030765773
-
Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin
-
Xiao B, Goh JY, Xiao L, Xian H, Lim KL, Liou YC. Reactive oxygen species trigger Parkin/PINK1 pathway-dependent mitophagy by inducing mitochondrial recruitment of Parkin. J Biol Chem. 2017;292:16697-16708. doi: 10.1074/jbc.M117.787739.
-
(2017)
J Biol Chem
, vol.292
, pp. 16697-16708
-
-
Xiao, B.1
Goh, J.Y.2
Xiao, L.3
Xian, H.4
Lim, K.L.5
Liou, Y.C.6
-
190
-
-
59249084491
-
The proteasome: Overview of structure and functions
-
Tanaka K. The proteasome: overview of structure and functions. Proc Jpn Acad Ser B Phys Biol Sci. 2009;85:12-36.
-
(2009)
Proc Jpn Acad Ser B Phys Biol Sci
, vol.85
, pp. 12-36
-
-
Tanaka, K.1
-
191
-
-
29344464782
-
Protein synthesis upon acute nutrient restriction relies on proteasome function
-
Vabulas RM, Hartl FU. Protein synthesis upon acute nutrient restriction relies on proteasome function. Science. 2005;310:1960-1963. doi: 10.1126/science.1121925.
-
(2005)
Science
, vol.310
, pp. 1960-1963
-
-
Vabulas, R.M.1
Hartl, F.U.2
-
192
-
-
0035072229
-
Degradation of oxidized proteins by the 20S proteasome
-
Davies KJ. Degradation of oxidized proteins by the 20S proteasome. Biochimie. 2001;83:301-310.
-
(2001)
Biochimie
, vol.83
, pp. 301-310
-
-
Davies, K.J.1
-
193
-
-
0029984892
-
Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome
-
Grune T, Reinheckel T, Davies KJ. Degradation of oxidized proteins in K562 human hematopoietic cells by proteasome. J Biol Chem. 1996;271:15504-15509.
-
(1996)
J Biol Chem
, vol.271
, pp. 15504-15509
-
-
Grune, T.1
Reinheckel, T.2
Davies, K.J.3
-
194
-
-
0037414834
-
Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome
-
Shringarpure R, Grune T, Mehlhase J, Davies KJ. Ubiquitin conjugation is not required for the degradation of oxidized proteins by proteasome. J Biol Chem. 2003;278:311-318. doi: 10.1074/jbc.M206279200.
-
(2003)
J Biol Chem
, vol.278
, pp. 311-318
-
-
Shringarpure, R.1
Grune, T.2
Mehlhase, J.3
Davies, K.J.4
-
195
-
-
0030987824
-
Subunit arrangement in the human 20s proteasome
-
Kopp F, Hendil KB, Dahlmann B, Kristensen P, Sobek A, Uerkvitz W. Subunit arrangement in the human 20s proteasome. Proc Natl Acad Sci USA 1997;94:2939-2944.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 2939-2944
-
-
Kopp, F.1
Hendil, K.B.2
Dahlmann, B.3
Kristensen, P.4
Sobek, A.5
Uerkvitz, W.6
-
196
-
-
33745816760
-
Protein degradation by the ubiquitin-proteasome pathway in normal and disease states
-
Lecker SH, Goldberg AL, Mitch WE. Protein degradation by the ubiquitin-proteasome pathway in normal and disease states. J Am Soc Nephrol. 2006;17:1807-1819. doi: 10.1681/ASN.2006010083.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1807-1819
-
-
Lecker, S.H.1
Goldberg, A.L.2
Mitch, W.E.3
-
197
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
Glickman MH, Ciechanover A. The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. Physiol Rev. 2002;82:373-428. doi: 10.1152/physrev.00027.2001.
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
198
-
-
11844287006
-
Mobilizing the proteolytic machine: Cell biological roles of proteasome activators and inhibitors
-
Rechsteiner M, Hill CP. Mobilizing the proteolytic machine: cell biological roles of proteasome activators and inhibitors. Trends Cell Biol. 2005;15:27-33. doi: 10.1016/j.tcb.2004.11.003.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 27-33
-
-
Rechsteiner, M.1
Hill, C.P.2
-
199
-
-
78649980437
-
Regulation of the 26S proteasome complex during oxidative stress
-
Wang X, Yen J, Kaiser P, Huang L. Regulation of the 26S proteasome complex during oxidative stress. Sci Signal. 2010;3:ra88. doi: 10.1126/ scisignal.2001232.
-
(2010)
Sci Signal
, vol.3
, pp. ra88
-
-
Wang, X.1
Yen, J.2
Kaiser, P.3
Huang, L.4
-
200
-
-
0028905549
-
Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells
-
Shang F, Taylor A. Oxidative stress and recovery from oxidative stress are associated with altered ubiquitin conjugating and proteolytic activities in bovine lens epithelial cells. Biochem J. 1995;307(pt 1):297-303.
-
(1995)
Biochem J
, vol.307
, pp. 297-303
-
-
Shang, F.1
Taylor, A.2
-
201
-
-
0032212875
-
Comparative resistance of the 20s and 26s proteasome to oxidative stress
-
Reinheckel T, Sitte N, Ullrich O, Kuckelkorn U, Davies KJ, Grune T. Comparative resistance of the 20s and 26s proteasome to oxidative stress. Biochem J. 1998;335:637-642.
-
(1998)
Biochem J
, vol.335
, pp. 637-642
-
-
Reinheckel, T.1
Sitte, N.2
Ullrich, O.3
Kuckelkorn, U.4
Davies, K.J.5
Grune, T.6
-
202
-
-
0037102467
-
Increased degradation of oxidized proteins in yeast defective in 26 S proteasome assembly
-
Inai Y, Nishikimi M. Increased degradation of oxidized proteins in yeast defective in 26 S proteasome assembly. Arch Biochem Biophys. 2002;404:279-284.
-
(2002)
Arch Biochem Biophys
, vol.404
, pp. 279-284
-
-
Inai, Y.1
Nishikimi, M.2
-
203
-
-
77956527159
-
Enhancement of proteasome activity by a small-molecule inhibitor of USP14
-
Lee BH, Lee MJ, Park S, Oh DC, Elsasser S, Chen PC, Gartner C, Dimova N, Hanna J, Gygi SP, Wilson SM, King RW, Finley D. Enhancement of proteasome activity by a small-molecule inhibitor of USP14. Nature. 2010;467:179-184. doi: 10.1038/nature09299.
-
(2010)
Nature
, vol.467
, pp. 179-184
-
-
Lee, B.H.1
Lee, M.J.2
Park, S.3
Oh, D.C.4
Elsasser, S.5
Chen, P.C.6
Gartner, C.7
Dimova, N.8
Hanna, J.9
Gygi, S.P.10
Wilson, S.M.11
King, R.W.12
Finley, D.13
-
204
-
-
33748105296
-
Glutathiolation enhances the degradation of gammaC-crystallin in lens and reticulocyte lysates, partially via the ubiquitin-proteasome pathway
-
Zetterberg M, Zhang X, Taylor A, Liu B, Liang JJ, Shang F. Glutathiolation enhances the degradation of gammaC-crystallin in lens and reticulocyte lysates, partially via the ubiquitin-proteasome pathway. Invest Ophthalmol Vis Sci. 2006;47:3467-3473. doi: 10.1167/iovs.05-1664.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 3467-3473
-
-
Zetterberg, M.1
Zhang, X.2
Taylor, A.3
Liu, B.4
Liang, J.J.5
Shang, F.6
-
205
-
-
0030881029
-
Activity of ubiquitin-dependent pathway in response to oxidative stress. Ubiquitin-activating enzyme is transiently up-regulated
-
Shang F, Gong X, Taylor A. Activity of ubiquitin-dependent pathway in response to oxidative stress. Ubiquitin-activating enzyme is transiently up-regulated. J Biol Chem. 1997;272:23086-23093.
-
(1997)
J Biol Chem
, vol.272
, pp. 23086-23093
-
-
Shang, F.1
Gong, X.2
Taylor, A.3
-
206
-
-
0141989227
-
Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2
-
Yamanaka K, Ishikawa H, Megumi Y, Tokunaga F, Kanie M, Rouault TA, Morishima I, Minato N, Ishimori K, Iwai K. Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2. Nat Cell Biol. 2003;5:336-340. doi: 10.1038/ncb952.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 336-340
-
-
Yamanaka, K.1
Ishikawa, H.2
Megumi, Y.3
Tokunaga, F.4
Kanie, M.5
Rouault, T.A.6
Morishima, I.7
Minato, N.8
Ishimori, K.9
Iwai, K.10
-
207
-
-
27144441722
-
Oxidative modification of proteasome: Identification of an oxidation-sensitive subunit in 26 S proteasome
-
Ishii T, Sakurai T, Usami H, Uchida K. Oxidative modification of proteasome: identification of an oxidation-sensitive subunit in 26 S proteasome. Biochemistry. 2005;44:13893-13901. doi: 10.1021/bi051336u.
-
(2005)
Biochemistry
, vol.44
, pp. 13893-13901
-
-
Ishii, T.1
Sakurai, T.2
Usami, H.3
Uchida, K.4
-
208
-
-
0035839573
-
Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion
-
Bulteau AL, Lundberg KC, Humphries KM, Sadek HA, Szweda PA, Friguet B, Szweda LI. Oxidative modification and inactivation of the proteasome during coronary occlusion/reperfusion. J Biol Chem. 2001;276:30057-30063. doi: 10.1074/jbc.M100142200.
-
(2001)
J Biol Chem
, vol.276
, pp. 30057-30063
-
-
Bulteau, A.L.1
Lundberg, K.C.2
Humphries, K.M.3
Sadek, H.A.4
Szweda, P.A.5
Friguet, B.6
Szweda, L.I.7
-
209
-
-
27244462417
-
Glutathiolation of the proteasome is enhanced by proteolytic inhibitors
-
Demasi M, Shringarpure R, Davies KJ. Glutathiolation of the proteasome is enhanced by proteolytic inhibitors. Arch Biochem Biophys. 2001;389:254-263. doi: 10.1006/abbi.2001.2332.
-
(2001)
Arch Biochem Biophys
, vol.389
, pp. 254-263
-
-
Demasi, M.1
Shringarpure, R.2
Davies, K.J.3
-
210
-
-
0033033698
-
Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones
-
Ullrich O, Reinheckel T, Sitte N, Hass R, Grune T, Davies KJ. Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones. Proc Natl Acad Sci USA. 1999;96:6223-6228.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6223-6228
-
-
Ullrich, O.1
Reinheckel, T.2
Sitte, N.3
Hass, R.4
Grune, T.5
Davies, K.J.6
-
211
-
-
36849043546
-
Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1
-
Fujino G, Noguchi T, Matsuzawa A, Yamauchi S, Saitoh M, Takeda K, Ichijo H. Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. Mol Cell Biol. 2007;27:8152-8163. doi: 10.1128/MCB.00227-07.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 8152-8163
-
-
Fujino, G.1
Noguchi, T.2
Matsuzawa, A.3
Yamauchi, S.4
Saitoh, M.5
Takeda, K.6
Ichijo, H.7
-
212
-
-
78449252451
-
ASK1 negatively regulates the 26 S proteasome
-
Um JW, Im E, Park J, Oh Y, Min B, Lee HJ, Yoon JB, Chung KC. ASK1 negatively regulates the 26 S proteasome. J Biol Chem. 2010;285:36434-36446. doi: 10.1074/jbc.M110.133777.
-
(2010)
J Biol Chem
, vol.285
, pp. 36434-36446
-
-
Um, J.W.1
Im, E.2
Park, J.3
Oh, Y.4
Min, B.5
Lee, H.J.6
Yoon, J.B.7
Chung, K.C.8
-
213
-
-
27744559915
-
Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalo-some is essential for oxidative stress-induced cell death
-
Noguchi T, Takeda K, Matsuzawa A, Saegusa K, Nakano H, Gohda J, Inoue J, Ichijo H. Recruitment of tumor necrosis factor receptor-associated factor family proteins to apoptosis signal-regulating kinase 1 signalo-some is essential for oxidative stress-induced cell death. J Biol Chem. 2005;280:37033-37040. doi: 10.1074/jbc.M506771200.
-
(2005)
J Biol Chem
, vol.280
, pp. 37033-37040
-
-
Noguchi, T.1
Takeda, K.2
Matsuzawa, A.3
Saegusa, K.4
Nakano, H.5
Gohda, J.6
Inoue, J.7
Ichijo, H.8
-
214
-
-
78649848069
-
The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes
-
Pickering AM, Koop AL, Teoh CY, Ermak G, Grune T, Davies KJ. The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes. Biochem J. 2010;432:585-594. doi: 10.1042/BJ20100878.
-
(2010)
Biochem J
, vol.432
, pp. 585-594
-
-
Pickering, A.M.1
Koop, A.L.2
Teoh, C.Y.3
Ermak, G.4
Grune, T.5
Davies, K.J.6
-
215
-
-
0037860832
-
Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress
-
Ding Q, Reinacker K, Dimayuga E, Nukala V, Drake J, Butterfield DA, Dunn JC, Martin S, Bruce-Keller AJ, Keller JN. Role of the proteasome in protein oxidation and neural viability following low-level oxidative stress. FEBS Lett. 2003;546:228-232.
-
(2003)
FEBS Lett
, vol.546
, pp. 228-232
-
-
Ding, Q.1
Reinacker, K.2
Dimayuga, E.3
Nukala, V.4
Drake, J.5
Butterfield, D.A.6
Dunn, J.C.7
Martin, S.8
Bruce-Keller, A.J.9
Keller, J.N.10
-
216
-
-
0029878931
-
Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit
-
Nandi D, Jiang H, Monaco JJ. Identification of MECL-1 (LMP-10) as the third IFN-gamma-inducible proteasome subunit. J Immunol. 1996;156:2361-2364.
-
(1996)
J Immunol
, vol.156
, pp. 2361-2364
-
-
Nandi, D.1
Jiang, H.2
Monaco, J.J.3
-
217
-
-
84928254049
-
Recent insights into the cellular biology of atherosclerosis
-
Tabas I, García-Cardeña G, Owens GK. Recent insights into the cellular biology of atherosclerosis. J Cell Biol. 2015;209:13-22. doi: 10.1083/ jcb.201412052.
-
(2015)
J Cell Biol
, vol.209
, pp. 13-22
-
-
Tabas, I.1
García-Cardeña, G.2
Owens, G.K.3
-
218
-
-
0034648768
-
Atherosclerosis
-
Lusis AJ. Atherosclerosis. Nature. 2000;407:233-241. doi: 10.1038/35025203.
-
(2000)
Nature
, vol.407
, pp. 233-241
-
-
Lusis, A.J.1
-
219
-
-
0034837376
-
Cardiovascular morbidity and mortality associated with the metabolic syndrome
-
Isomaa B, Almgren P, Tuomi T, Forsén B, Lahti K, Nissén M, Taskinen MR, Groop L. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care. 2001;24:683-689.
-
(2001)
Diabetes Care
, vol.24
, pp. 683-689
-
-
Isomaa, B.1
Almgren, P.2
Tuomi, T.3
Forsén, B.4
Lahti, K.5
Nissén, M.6
Taskinen, M.R.7
Groop, L.8
-
220
-
-
0037453031
-
Obesity, insulin resistance, diabetes, and cardiovascular risk in children
-
Steinberger J, Daniels SR. Obesity, insulin resistance, diabetes, and cardiovascular risk in children. An American Heart Association Scientific Statement From the Atherosclerosis, Hypertension, and Obesity in the Young Committee (Council on Cardiovascular Disease in the Young) and the Diabetes Committee (Council on Nutrition, Physical Activity, and Metabolism). 2003;107:1448-1453.
-
(2003)
An American Heart Association Scientific Statement From The Atherosclerosis, Hypertension, and Obesity in The Young Committee (Council on Cardiovascular Disease in The Young) and The Diabetes Committee (Council on Nutrition, Physical Activity, and Metabolism)
, vol.107
, pp. 1448-1453
-
-
Steinberger, J.1
Daniels, S.R.2
-
221
-
-
0024603895
-
Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity
-
Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med. 1989;320:915-924. doi: 10.1056/ NEJM198904063201407.
-
(1989)
N Engl J Med
, vol.320
, pp. 915-924
-
-
Steinberg, D.1
Parthasarathy, S.2
Carew, T.E.3
Khoo, J.C.4
Witztum, J.L.5
-
222
-
-
0034121607
-
Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice
-
Kirk EA, Dinauer MC, Rosen H, Chait A, Heinecke JW, LeBoeuf RC. Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice. Arterioscler Thromb Vasc Biol. 2000;20:1529-1535.
-
(2000)
Arterioscler Thromb Vasc Biol
, vol.20
, pp. 1529-1535
-
-
Kirk, E.A.1
Dinauer, M.C.2
Rosen, H.3
Chait, A.4
Heinecke, J.W.5
LeBoeuf, R.C.6
-
223
-
-
0034696590
-
Vascular effects following homozygous disruption of p47(phox): An essential component of NADPH oxidase
-
Hsich E, Segal BH, Pagano PJ, Rey FE, Paigen B, Deleonardis J, Hoyt RF, Holland SM, Finkel T. Vascular effects following homozygous disruption of p47(phox): an essential component of NADPH oxidase. Circulation. 2000;101:1234-1236.
-
(2000)
Circulation
, vol.101
, pp. 1234-1236
-
-
Hsich, E.1
Segal, B.H.2
Pagano, P.J.3
Rey, F.E.4
Paigen, B.5
Deleonardis, J.6
Hoyt, R.F.7
Holland, S.M.8
Finkel, T.9
-
224
-
-
0035179016
-
P47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice
-
Barry-Lane PA, Patterson C, van der Merwe M, Hu Z, Holland SM, Yeh ET, Runge MS. p47phox is required for atherosclerotic lesion progression in ApoE(-/-) mice. J Clin Invest. 2001;108:1513-1522. doi: 10.1172/JCI11927.
-
(2001)
J Clin Invest
, vol.108
, pp. 1513-1522
-
-
Barry-Lane, P.A.1
Patterson, C.2
Van Der Merwe, M.3
Hu, Z.4
Holland, S.M.5
Yeh, E.T.6
Runge, M.S.7
-
225
-
-
73549096170
-
Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- Mice
-
Judkins CP, Diep H, Broughton BR, Mast AE, Hooker EU, Miller AA, Selemidis S, Dusting GJ, Sobey CG, Drummond GR. Direct evidence of a role for Nox2 in superoxide production, reduced nitric oxide bioavailability, and early atherosclerotic plaque formation in ApoE-/- mice. Am J Physiol Heart Circ Physiol. 2010;298:H24-H32. doi: 10.1152/ ajpheart.00799.2009.
-
(2010)
Am J Physiol Heart Circ Physiol
, vol.298
, pp. H24-H32
-
-
Judkins, C.P.1
Diep, H.2
Broughton, B.R.3
Mast, A.E.4
Hooker, E.U.5
Miller, A.A.6
Selemidis, S.7
Dusting, G.J.8
Sobey, C.G.9
Drummond, G.R.10
-
226
-
-
85014330866
-
Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- Mice
-
Lond
-
Di Marco E, Gray SP, Chew P, Kennedy K, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- mice. Clin Sci (Lond). 2016;130:1363-1374. doi: 10.1042/CS20160249.
-
(2016)
Clin Sci (
, vol.130
, pp. 1363-1374
-
-
Di Marco, E.1
Gray, S.P.2
Chew, P.3
Kennedy, K.4
Cooper, M.E.5
Schmidt, H.H.6
Jandeleit-Dahm, K.A.7
-
227
-
-
79958011291
-
Role for Nox1 NADPH oxidase in atherosclerosis
-
Sheehan AL, Carrell S, Johnson B, Stanic B, Banfi B, Miller FJ Jr. Role for Nox1 NADPH oxidase in atherosclerosis. Atherosclerosis. 2011;216:321-326. doi: 10.1016/j.atherosclerosis.2011.02.028.
-
(2011)
Atherosclerosis
, vol.216
, pp. 321-326
-
-
Sheehan, A.L.1
Carrell, S.2
Johnson, B.3
Stanic, B.4
Banfi, B.5
Jr, M.F.J.6
-
228
-
-
84877270825
-
NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis
-
Gray SP, Di Marco E, Okabe J, et al. NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis. Circulation. 2013;127:1888-1902. doi: 10.1161/CIRCULATIONAHA.112.132159.
-
(2013)
Circulation
, vol.127
, pp. 1888-1902
-
-
Gray, S.P.1
Di Marco, E.2
Okabe, J.3
-
229
-
-
84955757208
-
Reactive oxygen species can provide atheroprotection via NOX4-dependent inhibition of inflammation and vascular remodeling
-
Gray SP, Di Marco E, Kennedy K, Chew P, Okabe J, El-Osta A, Calkin AC, Biessen EA, Touyz RM, Cooper ME, Schmidt HH, Jandeleit-Dahm KA. Reactive oxygen species can provide atheroprotection via NOX4-dependent inhibition of inflammation and vascular remodeling. Arterioscler Thromb Vasc Biol. 2016;36:295-307. doi: 10.1161/ ATVBAHA.115.307012.
-
(2016)
Arterioscler Thromb Vasc Biol
, vol.36
, pp. 295-307
-
-
Gray, S.P.1
Di Marco, E.2
Kennedy, K.3
Chew, P.4
Okabe, J.5
El-Osta, A.6
Calkin, A.C.7
Biessen, E.A.8
Touyz, R.M.9
Cooper, M.E.10
Schmidt, H.H.11
Jandeleit-Dahm, K.A.12
-
230
-
-
63449105018
-
Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation
-
Lee MY, San Martin A, Mehta PK, Dikalova AE, Garrido AM, Datla SR, Lyons E, Krause KH, Banfi B, Lambeth JD, Lassègue B, Griendling KK. Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation. Arterioscler Thromb Vasc Biol. 2009;29:480-487. doi: 10.1161/ ATVBAHA.108.181925.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 480-487
-
-
Lee, M.Y.1
San Martin, A.2
Mehta, P.K.3
Dikalova, A.E.4
Garrido, A.M.5
Datla, S.R.6
Lyons, E.7
Krause, K.H.8
Banfi, B.9
Lambeth, J.D.10
Lassègue, B.11
Griendling, K.K.12
-
231
-
-
84927800315
-
Phosphorylation of Nox1 regulates association with NoxA1 activation domain
-
Streeter J, Schickling BM, Jiang S, Stanic B, Thiel WH, Gakhar L, Houtman JC, Miller FJ Jr. Phosphorylation of Nox1 regulates association with NoxA1 activation domain. Circ Res. 2014;115:911-918. doi: 10.1161/CIRCRESAHA.115.304267.
-
(2014)
Circ Res
, vol.115
, pp. 911-918
-
-
Streeter, J.1
Schickling, B.M.2
Jiang, S.3
Stanic, B.4
Thiel, W.H.5
Gakhar, L.6
Houtman, J.C.7
Jr, M.F.J.8
-
232
-
-
84926612601
-
NOX1 deficiency in apolipoprotein E-knockout mice is associated with elevated plasma lipids and enhanced atherosclerosis
-
Sobey CG, Judkins CP, Rivera J, Lewis CV, Diep H, Lee HW, Kemp-Harper BK, Broughton BR, Selemidis S, Gaspari TA, Samuel CS, Drummond GR. NOX1 deficiency in apolipoprotein E-knockout mice is associated with elevated plasma lipids and enhanced atherosclerosis. Free Radic Res. 2015;49:186-198. doi: 10.3109/10715762.2014.992893.
-
(2015)
Free Radic Res
, vol.49
, pp. 186-198
-
-
Sobey, C.G.1
Judkins, C.P.2
Rivera, J.3
Lewis, C.V.4
Diep, H.5
Lee, H.W.6
Kemp-Harper, B.K.7
Broughton, B.R.8
Selemidis, S.9
Gaspari, T.A.10
Samuel, C.S.11
Drummond, G.R.12
-
233
-
-
84939817635
-
Selective inactivation of NADPH oxidase 2 causes regression of vascularization and the size and stability of atherosclerotic plaques
-
Quesada IM, Lucero A, Amaya C, Meijles DN, Cifuentes ME, Pagano PJ, Castro C. Selective inactivation of NADPH oxidase 2 causes regression of vascularization and the size and stability of atherosclerotic plaques. Atherosclerosis. 2015;242:469-475. doi: 10.1016/j. atherosclerosis.2015.08.011.
-
(2015)
Atherosclerosis
, vol.242
, pp. 469-475
-
-
Quesada, I.M.1
Lucero, A.2
Amaya, C.3
Meijles, D.N.4
Cifuentes, M.E.5
Pagano, P.J.6
Castro, C.7
-
235
-
-
36349024676
-
Atherosclerosis is attenuated by limiting superoxide generation in both macrophages and vessel wall cells
-
Vendrov AE, Hakim ZS, Madamanchi NR, Rojas M, Madamanchi C, Runge MS. Atherosclerosis is attenuated by limiting superoxide generation in both macrophages and vessel wall cells. Arterioscler Thromb Vasc Biol. 2007;27:2714-2721. doi: 10.1161/ATVBAHA.107.152629.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 2714-2721
-
-
Vendrov, A.E.1
Hakim, Z.S.2
Madamanchi, N.R.3
Rojas, M.4
Madamanchi, C.5
Runge, M.S.6
-
236
-
-
0034724687
-
Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species
-
Cominacini L, Pasini AF, Garbin U, Davoli A, Tosetti ML, Campagnola M, Rigoni A, Pastorino AM, Lo Cascio V, Sawamura T. Oxidized low density lipoprotein (ox-LDL) binding to ox-LDL receptor-1 in endothelial cells induces the activation of NF-kappaB through an increased production of intracellular reactive oxygen species. J Biol Chem. 2000;275:12633-12638.
-
(2000)
J Biol Chem
, vol.275
, pp. 12633-12638
-
-
Cominacini, L.1
Pasini, A.F.2
Garbin, U.3
Davoli, A.4
Tosetti, M.L.5
Campagnola, M.6
Rigoni, A.7
Pastorino, A.M.8
Lo Cascio, V.9
Sawamura, T.10
-
237
-
-
80053260510
-
Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway
-
Tsai KL, Chen LH, Chiou SH, Chiou GY, Chen YC, Chou HY, Chen LK, Chen HY, Chiu TH, Tsai CS, Ou HC, Kao CL. Coenzyme Q10 suppresses oxLDL-induced endothelial oxidative injuries by the modulation of LOX-1-mediated ROS generation via the AMPK/PKC/NADPH oxidase signaling pathway. Mol Nutr Food Res. 2011;55(suppl 2):S227-S240. doi: 10.1002/mnfr.201100147.
-
(2011)
Mol Nutr Food Res
, vol.55
, pp. S227-S240
-
-
Tsai, K.L.1
Chen, L.H.2
Chiou, S.H.3
Chiou, G.Y.4
Chen, Y.C.5
Chou, H.Y.6
Chen, L.K.7
Chen, H.Y.8
Chiu, T.H.9
Tsai, C.S.10
Ou, H.C.11
Kao, C.L.12
-
238
-
-
59849086158
-
Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: Toll-like receptor 4- And spleen tyrosine kinase-dependent activation of NADPH oxidase 2
-
21p following 218.
-
Bae YS, Lee JH, Choi SH, Kim S, Almazan F, Witztum JL, Miller YI. Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2. Circ Res. 2009;104:210-218, 21p following 218. doi: 10.1161/ CIRCRESAHA.108.181040.
-
(2009)
Circ Res
, vol.104
, pp. 210-218
-
-
Bae, Y.S.1
Lee, J.H.2
Choi, S.H.3
Kim, S.4
Almazan, F.5
Witztum, J.L.6
Miller, Y.I.7
-
239
-
-
0037428382
-
Oxidized LDL promotes peroxide-mediated mitochondrial dysfunction and cell death in human macrophages: A caspase-3-independent pathway
-
Asmis R, Begley JG. Oxidized LDL promotes peroxide-mediated mitochondrial dysfunction and cell death in human macrophages: a caspase-3-independent pathway. Circ Res. 2003;92:e20-e29.
-
(2003)
Circ Res
, vol.92
, pp. e20-e29
-
-
Asmis, R.1
Begley, J.G.2
-
240
-
-
0034749387
-
Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells
-
Hsieh CC, Yen MH, Yen CH, Lau YT. Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells. Cardiovasc Res. 2001;49:135-145.
-
(2001)
Cardiovasc Res
, vol.49
, pp. 135-145
-
-
Hsieh, C.C.1
Yen, M.H.2
Yen, C.H.3
Lau, Y.T.4
-
241
-
-
12544258729
-
Macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein
-
Kruth HS, Jones NL, Huang W, Zhao B, Ishii I, Chang J, Combs CA, Malide D, Zhang WY. Macropinocytosis is the endocytic pathway that mediates macrophage foam cell formation with native low density lipoprotein. J Biol Chem. 2005;280:2352-2360. doi: 10.1074/jbc. M407167200.
-
(2005)
J Biol Chem
, vol.280
, pp. 2352-2360
-
-
Kruth, H.S.1
Jones, N.L.2
Huang, W.3
Zhao, B.4
Ishii, I.5
Chang, J.6
Combs, C.A.7
Malide, D.8
Zhang, W.Y.9
-
242
-
-
85019347255
-
Nox2-mediated PI3K and cofilin activation confers alternate redox control of macrophage pinocytosis
-
Ghoshal P, Singla B, Lin H, Feck DM, Cantu-Medellin N, Kelley EE, Haigh S, Fulton D, Csányi G. Nox2-mediated PI3K and cofilin activation confers alternate redox control of macrophage pinocytosis. Antioxid Redox Signal. 2017;26:902-916. doi: 10.1089/ars.2016.6639.
-
(2017)
Antioxid Redox Signal
, vol.26
, pp. 902-916
-
-
Ghoshal, P.1
Singla, B.2
Lin, H.3
Feck, D.M.4
Cantu-Medellin, N.5
Kelley, E.E.6
Haigh, S.7
Fulton, D.8
Csányi, G.9
-
243
-
-
84976433528
-
NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice
-
Langbein H, Brunssen C, Hofmann A, Cimalla P, Brux M, Bornstein SR, Deussen A, Koch E, Morawietz H. NADPH oxidase 4 protects against development of endothelial dysfunction and atherosclerosis in LDL receptor deficient mice. Eur Heart J. 2016;37:1753-1761. doi: 10.1093/ eurheartj/ehv564.
-
(2016)
Eur Heart J
, vol.37
, pp. 1753-1761
-
-
Langbein, H.1
Brunssen, C.2
Hofmann, A.3
Cimalla, P.4
Brux, M.5
Bornstein, S.R.6
Deussen, A.7
Koch, E.8
Morawietz, H.9
-
244
-
-
84952042542
-
The NADPH oxidase Nox4 has anti-atherosclerotic functions
-
Schürmann C, Rezende F, Kruse C, Yasar Y, Löwe O, Fork C, van de Sluis B, Bremer R, Weissmann N, Shah AM, Jo H, Brandes RP, Schröder K. The NADPH oxidase Nox4 has anti-atherosclerotic functions. Eur Heart J. 2015;36:3447-3456. doi: 10.1093/eurheartj/ehv460.
-
(2015)
Eur Heart J
, vol.36
, pp. 3447-3456
-
-
Schürmann, C.1
Rezende, F.2
Kruse, C.3
Yasar, Y.4
Löwe, O.5
Fork, C.6
Van De Sluis, B.7
Bremer, R.8
Weissmann, N.9
Shah, A.M.10
Jo, H.11
Brandes, R.P.12
Schröder, K.13
-
245
-
-
84979650344
-
NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis
-
Di Marco E, Gray SP, Kennedy K, Szyndralewiez C, Lyle AN, Lassègue B, Griendling KK, Cooper ME, Schmidt HHHW, Jandeleit-Dahm KAM. NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis. Free Radic Biol Med. 2016;97:556-567. doi: 10.1016/j. freeradbiomed.2016.07.013.
-
(2016)
Free Radic Biol Med
, vol.97
, pp. 556-567
-
-
Di Marco, E.1
Gray, S.P.2
Kennedy, K.3
Szyndralewiez, C.4
Lyle, A.N.5
Lassègue, B.6
Griendling, K.K.7
Cooper, M.E.8
Schmidt, H.H.H.W.9
Jandeleit-Dahm, K.A.M.10
-
246
-
-
85018268587
-
Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase
-
Hu P, Wu X, Khandelwal AR, Yu W, Xu Z, Chen L, Yang J, Weisbrod RM, Lee KSS, Seta F, Hammock BD, Cohen RA, Zeng C, Tong X. Endothelial Nox4-based NADPH oxidase regulates atherosclerosis via soluble epoxide hydrolase. Biochim Biophys Acta. 2017;1863:1382-1391. doi: 10.1016/j.bbadis.2017.02.004.
-
(2017)
Biochim Biophys Acta
, vol.1863
, pp. 1382-1391
-
-
Hu, P.1
Wu, X.2
Khandelwal, A.R.3
Yu, W.4
Xu, Z.5
Chen, L.6
Yang, J.7
Weisbrod, R.M.8
Lee, K.S.S.9
Seta, F.10
Hammock, B.D.11
Cohen, R.A.12
Zeng, C.13
Tong, X.14
-
247
-
-
84941201574
-
Endothelial NADPH oxidase 4 protects ApoE-/- Mice from atherosclerotic lesions
-
Craige SM, Kant S, Reif M, Chen K, Pei Y, Angoff R, Sugamura K, Fitzgibbons T, Keaney JF Jr. Endothelial NADPH oxidase 4 protects ApoE-/- mice from atherosclerotic lesions. Free Radic Biol Med. 2015;89:1-7. doi: 10.1016/j.freeradbiomed.2015.07.004.
-
(2015)
Free Radic Biol Med
, vol.89
, pp. 1-7
-
-
Craige, S.M.1
Kant, S.2
Reif, M.3
Chen, K.4
Pei, Y.5
Angoff, R.6
Sugamura, K.7
Fitzgibbons, T.8
Jr, K.J.F.9
-
248
-
-
84899137808
-
Nox4 NADPH oxidase contributes to smooth muscle cell phenotypes associated with unstable atherosclerotic plaques
-
Xu S, Chamseddine AH, Carrell S, Miller FJ Jr. Nox4 NADPH oxidase contributes to smooth muscle cell phenotypes associated with unstable atherosclerotic plaques. Redox Biol. 2014;2:642-650. doi: 10.1016/j. redox.2014.04.004.
-
(2014)
Redox Biol
, vol.2
, pp. 642-650
-
-
Xu, S.1
Chamseddine, A.H.2
Carrell, S.3
Jr, M.F.J.4
-
249
-
-
84944941523
-
NOX4 NADPH oxidase-dependent mitochondrial oxidative stress in aging-associated cardiovascular disease
-
Vendrov AE, Vendrov KC, Smith A, Yuan J, Sumida A, Robidoux J, Runge MS, Madamanchi NR. NOX4 NADPH oxidase-dependent mitochondrial oxidative stress in aging-associated cardiovascular disease. Antioxid Redox Signal. 2015;23:1389-1409. doi: 10.1089/ars.2014.6221.
-
(2015)
Antioxid Redox Signal
, vol.23
, pp. 1389-1409
-
-
Vendrov, A.E.1
Vendrov, K.C.2
Smith, A.3
Yuan, J.4
Sumida, A.5
Robidoux, J.6
Runge, M.S.7
Madamanchi, N.R.8
-
250
-
-
84961328291
-
Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase
-
Tong X, Khandelwal AR, Wu X, et al. Pro-atherogenic role of smooth muscle Nox4-based NADPH oxidase. J Mol Cell Cardiol. 2016;92:30-40. doi: 10.1016/j.yjmcc.2016.01.020.
-
(2016)
J Mol Cell Cardiol
, vol.92
, pp. 30-40
-
-
Tong, X.1
Khandelwal, A.R.2
Wu, X.3
-
251
-
-
10044220931
-
NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells
-
Pedruzzi E, Guichard C, Ollivier V, et al. NAD(P)H oxidase Nox-4 mediates 7-ketocholesterol-induced endoplasmic reticulum stress and apoptosis in human aortic smooth muscle cells. Mol Cell Biol. 2004;24:10703-10717. doi: 10.1128/MCB.24.24.10703-10717.2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 10703-10717
-
-
Pedruzzi, E.1
Guichard, C.2
Ollivier, V.3
-
252
-
-
78650105442
-
NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis
-
Li G, Scull C, Ozcan L, Tabas I. NADPH oxidase links endoplasmic reticulum stress, oxidative stress, and PKR activation to induce apoptosis. J Cell Biol. 2010;191:1113-1125. doi: 10.1083/jcb.201006121.
-
(2010)
J Cell Biol
, vol.191
, pp. 1113-1125
-
-
Li, G.1
Scull, C.2
Ozcan, L.3
Tabas, I.4
-
253
-
-
65349135431
-
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe- /- And Ldlr-/- Mice lacking CHOP
-
Thorp E, Li G, Seimon TA, Kuriakose G, Ron D, Tabas I. Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe- /- and Ldlr-/- mice lacking CHOP. Cell Metab. 2009;9:474-481. doi: 10.1016/j.cmet.2009.03.003.
-
(2009)
Cell Metab
, vol.9
, pp. 474-481
-
-
Thorp, E.1
Li, G.2
Seimon, T.A.3
Kuriakose, G.4
Ron, D.5
Tabas, I.6
-
254
-
-
84942777039
-
C/EBP-Homologous Protein (CHOP) in vascular smooth muscle cells regulates their proliferation in aortic explants and atherosclerotic esions
-
Zhou AX, Wang X, Lin CS, Han J, Yong J, Nadolski MJ, Borén J, Kaufman RJ, Tabas I. C/EBP-Homologous Protein (CHOP) in vascular smooth muscle cells regulates their proliferation in aortic explants and atherosclerotic esions. Circ Res. 2015;116:1736-1743. doi: 10.1161/ CIRCRESAHA.116.305602.
-
(2015)
Circ Res
, vol.116
, pp. 1736-1743
-
-
Zhou, A.X.1
Wang, X.2
Lin, C.S.3
Han, J.4
Yong, J.5
Nadolski, M.J.6
Borén, J.7
Kaufman, R.J.8
Tabas, I.9
-
255
-
-
33646707463
-
Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(-/-) mice
-
Matsui R, Xu S, Maitland KA, Mastroianni R, Leopold JA, Handy DE, Loscalzo J, Cohen RA. Glucose-6-phosphate dehydrogenase deficiency decreases vascular superoxide and atherosclerotic lesions in apolipoprotein E(-/-) mice. Arterioscler Thromb Vasc Biol. 2006;26:910-916. doi: 10.1161/01.ATV.0000205850.49390.3b.
-
(2006)
Arterioscler Thromb Vasc Biol
, vol.26
, pp. 910-916
-
-
Matsui, R.1
Xu, S.2
Maitland, K.A.3
Mastroianni, R.4
Leopold, J.A.5
Handy, D.E.6
Loscalzo, J.7
Cohen, R.A.8
-
256
-
-
0037342685
-
Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide
-
Leopold JA, Zhang YY, Scribner AW, Stanton RC, Loscalzo J. Glucose-6-phosphate dehydrogenase overexpression decreases endothelial cell oxidant stress and increases bioavailable nitric oxide. Arterioscler Thromb Vasc Biol. 2003;23:411-417. doi: 10.1161/01.ATV.0000056744.26901.BA.
-
(2003)
Arterioscler Thromb Vasc Biol
, vol.23
, pp. 411-417
-
-
Leopold, J.A.1
Zhang, Y.Y.2
Scribner, A.W.3
Stanton, R.C.4
Loscalzo, J.5
-
257
-
-
84856752588
-
The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ ApoE-/- Mice
-
Mercer JR, Yu E, Figg N, Cheng KK, Prime TA, Griffin JL, Masoodi M, Vidal-Puig A, Murphy MP, Bennett MR. The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM+/-/ ApoE-/- mice. Free Radic Biol Med. 2012;52:841-849. doi: 10.1016/j. freeradbiomed.2011.11.026.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 841-849
-
-
Mercer, J.R.1
Yu, E.2
Figg, N.3
Cheng, K.K.4
Prime, T.A.5
Griffin, J.L.6
Masoodi, M.7
Vidal-Puig, A.8
Murphy, M.P.9
Bennett, M.R.10
-
258
-
-
84894070483
-
Macrophage mitochondrial oxidative stress promotes atherosclerosis and nuclear factor-κB-mediated inflammation in macrophages
-
Wang Y, Wang GZ, Rabinovitch PS, Tabas I. Macrophage mitochondrial oxidative stress promotes atherosclerosis and nuclear factor-κB-mediated inflammation in macrophages. Circ Res. 2014;114:421-433. doi: 10.1161/CIRCRESAHA.114.302153.
-
(2014)
Circ Res
, vol.114
, pp. 421-433
-
-
Wang, Y.1
Wang, G.Z.2
Rabinovitch, P.S.3
Tabas, I.4
-
259
-
-
85020662970
-
Mitochondrial oxidative stress promotes atherosclerosis and neutrophil extracellular traps in aged mice
-
Wang Y, Wang W, Wang N, Tall AR, Tabas I. Mitochondrial oxidative stress promotes atherosclerosis and neutrophil extracellular traps in aged mice. Arterioscler Thromb Vasc Biol. 2017;37:e99-e107. doi: 10.1161/ ATVBAHA.117.309580.
-
(2017)
Arterioscler Thromb Vasc Biol
, vol.37
, pp. e99-e107
-
-
Wang, Y.1
Wang, W.2
Wang, N.3
Tall, A.R.4
Tabas, I.5
-
260
-
-
85007302876
-
Metformin suppresses diabetes-accelerated atherosclerosis via the inhibition of Drp1-mediated mitochondrial fission
-
Wang Q, Zhang M, Torres G, Wu S, Ouyang C, Xie Z, Zou MH. Metformin suppresses diabetes-accelerated atherosclerosis via the inhibition of Drp1-mediated mitochondrial fission. Diabetes. 2017;66:193-205. doi: 10.2337/db16-0915.
-
(2017)
Diabetes
, vol.66
, pp. 193-205
-
-
Wang, Q.1
Zhang, M.2
Torres, G.3
Wu, S.4
Ouyang, C.5
Xie, Z.6
Zou, M.H.7
-
261
-
-
80051783174
-
Uncoupling proteins and the control of mitochondrial reactive oxygen species production
-
Mailloux RJ, Harper ME. Uncoupling proteins and the control of mitochondrial reactive oxygen species production. Free Radic Biol Med. 2011;51:1106-1115. doi: 10.1016/j.freeradbiomed.2011.06.022.
-
(2011)
Free Radic Biol Med
, vol.51
, pp. 1106-1115
-
-
Mailloux, R.J.1
Harper, M.E.2
-
262
-
-
63449141267
-
Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice
-
Moukdar F, Robidoux J, Lyght O, Pi J, Daniel KW, Collins S. Reduced antioxidant capacity and diet-induced atherosclerosis in uncoupling protein-2-deficient mice. J Lipid Res. 2009;50:59-70. doi: 10.1194/jlr. M800273-JLR200.
-
(2009)
J Lipid Res
, vol.50
, pp. 59-70
-
-
Moukdar, F.1
Robidoux, J.2
Lyght, O.3
Pi, J.4
Daniel, K.W.5
Collins, S.6
-
263
-
-
0037469183
-
Protective role of uncoupling protein 2 in atherosclerosis
-
Blanc J, Alves-Guerra MC, Esposito B, Rousset S, Gourdy P, Ricquier D, Tedgui A, Miroux B, Mallat Z. Protective role of uncoupling protein 2 in atherosclerosis. Circulation. 2003;107:388-390.
-
(2003)
Circulation
, vol.107
, pp. 388-390
-
-
Blanc, J.1
Alves-Guerra, M.C.2
Esposito, B.3
Rousset, S.4
Gourdy, P.5
Ricquier, D.6
Tedgui, A.7
Miroux, B.8
Mallat, Z.9
-
264
-
-
84897410215
-
Xanthine oxidase inhibition by febuxostat attenuates experimental atherosclerosis in mice
-
Nomura J, Busso N, Ives A, Matsui C, Tsujimoto S, Shirakura T, Tamura M, Kobayashi T, So A, Yamanaka Y. Xanthine oxidase inhibition by febuxostat attenuates experimental atherosclerosis in mice. Sci Rep. 2014;4:4554. doi: 10.1038/srep04554.
-
(2014)
Sci Rep
, vol.4
, pp. 4554
-
-
Nomura, J.1
Busso, N.2
Ives, A.3
Matsui, C.4
Tsujimoto, S.5
Shirakura, T.6
Tamura, M.7
Kobayashi, T.8
So, A.9
Yamanaka, Y.10
-
265
-
-
33749235510
-
Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet
-
Schröder K, Vecchione C, Jung O, Schreiber JG, Shiri-Sverdlov R, van Gorp PJ, Busse R, Brandes RP. Xanthine oxidase inhibitor tungsten prevents the development of atherosclerosis in ApoE knockout mice fed a Western-type diet. Free Radic Biol Med. 2006;41:1353-1360. doi: 10.1016/j.freeradbiomed.2006.03.026.
-
(2006)
Free Radic Biol Med
, vol.41
, pp. 1353-1360
-
-
Schröder, K.1
Vecchione, C.2
Jung, O.3
Schreiber, J.G.4
Shiri-Sverdlov, R.5
Van Gorp, P.J.6
Busse, R.7
Brandes, R.P.8
-
266
-
-
9344240424
-
Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E
-
Yang H, Roberts LJ, Shi MJ, Zhou LC, Ballard BR, Richardson A, Guo ZM. Retardation of atherosclerosis by overexpression of catalase or both Cu/Zn-superoxide dismutase and catalase in mice lacking apolipoprotein E. Circ Res. 2004;95:1075-1081. doi: 10.1161/01. RES.0000149564.49410.0d.
-
(2004)
Circ Res
, vol.95
, pp. 1075-1081
-
-
Yang, H.1
Roberts, L.J.2
Shi, M.J.3
Zhou, L.C.4
Ballard, B.R.5
Richardson, A.6
Guo, Z.M.7
-
267
-
-
84866279008
-
Overexpression of peroxiredoxin 4 attenuates atherosclerosis in apolipoprotein E knockout mice
-
Guo X, Yamada S, Tanimoto A, Ding Y, Wang KY, Shimajiri S, Murata Y, Kimura S, Tasaki T, Nabeshima A, Watanabe T, Kohno K, Sasaguri Y. Overexpression of peroxiredoxin 4 attenuates atherosclerosis in apolipoprotein E knockout mice. Antioxid Redox Signal. 2012;17:1362-1375. doi: 10.1089/ars.2012.4549.
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 1362-1375
-
-
Guo, X.1
Yamada, S.2
Tanimoto, A.3
Ding, Y.4
Wang, K.Y.5
Shimajiri, S.6
Murata, Y.7
Kimura, S.8
Tasaki, T.9
Nabeshima, A.10
Watanabe, T.11
Kohno, K.12
Sasaguri, Y.13
-
268
-
-
34247895799
-
Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions
-
Zhang H, Luo Y, Zhang W, He Y, Dai S, Zhang R, Huang Y, Bernatchez P, Giordano FJ, Shadel G, Sessa WC, Min W. Endothelial-specific expression of mitochondrial thioredoxin improves endothelial cell function and reduces atherosclerotic lesions. Am J Pathol. 2007;170:1108-1120. doi: 10.2353/ajpath.2007.060960.
-
(2007)
Am J Pathol
, vol.170
, pp. 1108-1120
-
-
Zhang, H.1
Luo, Y.2
Zhang, W.3
He, Y.4
Dai, S.5
Zhang, R.6
Huang, Y.7
Bernatchez, P.8
Giordano, F.J.9
Shadel, G.10
Sessa, W.C.11
Min, W.12
-
269
-
-
78650913866
-
NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection
-
Barajas B, Che N, Yin F, Rowshanrad A, Orozco LD, Gong KW, Wang X, Castellani LW, Reue K, Lusis AJ, Araujo JA. NF-E2-related factor 2 promotes atherosclerosis by effects on plasma lipoproteins and cholesterol transport that overshadow antioxidant protection. Arterioscler Thromb Vasc Biol. 2011;31:58-66. doi: 10.1161/ATVBAHA.110.210906.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 58-66
-
-
Barajas, B.1
Che, N.2
Yin, F.3
Rowshanrad, A.4
Orozco, L.D.5
Gong, K.W.6
Wang, X.7
Castellani, L.W.8
Reue, K.9
Lusis, A.J.10
Araujo, J.A.11
-
270
-
-
34247201155
-
Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice
-
Torzewski M, Ochsenhirt V, Kleschyov AL, Oelze M, Daiber A, Li H, Rossmann H, Tsimikas S, Reifenberg K, Cheng F, Lehr HA, Blankenberg S, Förstermann U, Münzel T, Lackner KJ. Deficiency of glutathione peroxidase-1 accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2007;27:850-857. doi: 10.1161/01.ATV.0000258809.47285.07.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, pp. 850-857
-
-
Torzewski, M.1
Ochsenhirt, V.2
Kleschyov, A.L.3
Oelze, M.4
Daiber, A.5
Li, H.6
Rossmann, H.7
Tsimikas, S.8
Reifenberg, K.9
Cheng, F.10
Lehr, H.A.11
Blankenberg, S.12
Förstermann, U.13
Münzel, T.14
Lackner, K.J.15
-
271
-
-
78650042004
-
Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse
-
Chew P, Yuen DY, Stefanovic N, Pete J, Coughlan MT, Jandeleit-Dahm KA, Thomas MC, Rosenfeldt F, Cooper ME, de Haan JB. Antiatherosclerotic and renoprotective effects of ebselen in the diabetic apolipoprotein E/GPx1-double knockout mouse. Diabetes. 2010;59:3198-3207. doi: 10.2337/db10-0195.
-
(2010)
Diabetes
, vol.59
, pp. 3198-3207
-
-
Chew, P.1
Yuen, D.Y.2
Stefanovic, N.3
Pete, J.4
Coughlan, M.T.5
Jandeleit-Dahm, K.A.6
Thomas, M.C.7
Rosenfeldt, F.8
Cooper, M.E.9
De Haan, J.B.10
-
272
-
-
0037199466
-
Mitochondrial integrity and function in atherogenesis
-
Ballinger SW, Patterson C, Knight-Lozano CA, Burow DL, Conklin CA, Hu Z, Reuf J, Horaist C, Lebovitz R, Hunter GC, McIntyre K, Runge MS. Mitochondrial integrity and function in atherogenesis. Circulation. 2002;106:544-549.
-
(2002)
Circulation
, vol.106
, pp. 544-549
-
-
Ballinger, S.W.1
Patterson, C.2
Knight-Lozano, C.A.3
Burow, D.L.4
Conklin, C.A.5
Hu, Z.6
Reuf, J.7
Horaist, C.8
Lebovitz, R.9
Hunter, G.C.10
McIntyre, K.11
Runge, M.S.12
-
273
-
-
53249125962
-
Peroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis
-
Kisucka J, Chauhan AK, Patten IS, Yesilaltay A, Neumann C, Van Etten RA, Krieger M, Wagner DD. Peroxiredoxin1 prevents excessive endothelial activation and early atherosclerosis. Circ Res. 2008;103:598-605. doi: 10.1161/CIRCRESAHA.108.174870.
-
(2008)
Circ Res
, vol.103
, pp. 598-605
-
-
Kisucka, J.1
Chauhan, A.K.2
Patten, I.S.3
Yesilaltay, A.4
Neumann, C.5
Van Etten, R.A.6
Krieger, M.7
Wagner, D.D.8
-
274
-
-
80052970775
-
Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice
-
Park JG, Yoo JY, Jeong SJ, Choi JH, Lee MR, Lee MN, Hwa Lee J, Kim HC, Jo H, Yu DY, Kang SW, Rhee SG, Lee MH, Oh GT. Peroxiredoxin 2 deficiency exacerbates atherosclerosis in apolipoprotein E-deficient mice. Circ Res. 2011;109:739-749. doi: 10.1161/CIRCRESAHA.111.245530.
-
(2011)
Circ Res
, vol.109
, pp. 739-749
-
-
Park, J.G.1
Yoo, J.Y.2
Jeong, S.J.3
Choi, J.H.4
Lee, M.R.5
Lee, M.N.6
Hwa Lee, J.7
Kim, H.C.8
Jo, H.9
Yu, D.Y.10
Kang, S.W.11
Rhee, S.G.12
Lee, M.H.13
Oh, G.T.14
-
276
-
-
80055007728
-
Paraoxonase 1 (PON1) inhibits monocyte-to-macrophage differentiation
-
Rosenblat M, Volkova N, Ward J, Aviram M. Paraoxonase 1 (PON1) inhibits monocyte-to-macrophage differentiation. Atherosclerosis. 2011;219:49-56. doi: 10.1016/j.atherosclerosis.2011.06.054.
-
(2011)
Atherosclerosis
, vol.219
, pp. 49-56
-
-
Rosenblat, M.1
Volkova, N.2
Ward, J.3
Aviram, M.4
-
277
-
-
66949179058
-
Human paraoxonase gene cluster transgenic overexpression represses atherogenesis and promotes atherosclerotic plaque stability in ApoE-null mice
-
She ZG, Zheng W, Wei YS, Chen HZ, Wang AB, Li HL, Liu G, Zhang R, Liu JJ, Stallcup WB, Zhou Z, Liu DP, Liang CC. Human paraoxonase gene cluster transgenic overexpression represses atherogenesis and promotes atherosclerotic plaque stability in ApoE-null mice. Circ Res. 2009;104:1160-1168. doi: 10.1161/CIRCRESAHA.108.192229.
-
(2009)
Circ Res
, vol.104
, pp. 1160-1168
-
-
She, Z.G.1
Zheng, W.2
Wei, Y.S.3
Chen, H.Z.4
Wang, A.B.5
Li, H.L.6
Liu, G.7
Zhang, R.8
Liu, J.J.9
Stallcup, W.B.10
Zhou, Z.11
Liu, D.P.12
Liang, C.C.13
-
278
-
-
84878113868
-
Paraoxonase 1 (PON1) reduces macrophage inflammatory responses
-
Aharoni S, Aviram M, Fuhrman B. Paraoxonase 1 (PON1) reduces macrophage inflammatory responses. Atherosclerosis. 2013;228:353-361. doi: 10.1016/j.atherosclerosis.2013.03.005.
-
(2013)
Atherosclerosis
, vol.228
, pp. 353-361
-
-
Aharoni, S.1
Aviram, M.2
Fuhrman, B.3
-
279
-
-
47149093201
-
Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia
-
Ng DS, Chu T, Esposito B, Hui P, Connelly PW, Gross PL. Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia. Cardiovasc Pathol. 2008;17:226-232. doi: 10.1016/j.carpath.2007.10.001.
-
(2008)
Cardiovasc Pathol
, vol.17
, pp. 226-232
-
-
Ng, D.S.1
Chu, T.2
Esposito, B.3
Hui, P.4
Connelly, P.W.5
Gross, P.L.6
-
280
-
-
78650869947
-
Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis
-
Devarajan A, Bourquard N, Hama S, Navab M, Grijalva VR, Morvardi S, Clarke CF, Vergnes L, Reue K, Teiber JF, Reddy ST. Paraoxonase 2 deficiency alters mitochondrial function and exacerbates the development of atherosclerosis. Antioxid Redox Signal. 2011;14:341-351. doi: 10.1089/ ars.2010.3430.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 341-351
-
-
Devarajan, A.1
Bourquard, N.2
Hama, S.3
Navab, M.4
Grijalva, V.R.5
Morvardi, S.6
Clarke, C.F.7
Vergnes, L.8
Reue, K.9
Teiber, J.F.10
Reddy, S.T.11
-
281
-
-
33749544927
-
Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: Anti-atherogenic role for paraoxonase-2
-
Ng CJ, Bourquard N, Grijalva V, Hama S, Shih DM, Navab M, Fogelman AM, Lusis AJ, Young S, Reddy ST. Paraoxonase-2 deficiency aggravates atherosclerosis in mice despite lower apolipoprotein-B-containing lipoproteins: anti-atherogenic role for paraoxonase-2. J Biol Chem. 2006;281:29491-29500. doi: 10.1074/jbc.M605379200.
-
(2006)
J Biol Chem
, vol.281
, pp. 29491-29500
-
-
Ng, C.J.1
Bourquard, N.2
Grijalva, V.3
Hama, S.4
Shih, D.M.5
Navab, M.6
Fogelman, A.M.7
Lusis, A.J.8
Young, S.9
Reddy, S.T.10
-
282
-
-
33845914986
-
Mechanisms linking obesity with cardiovascular disease
-
Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature. 2006;444:875-880. doi: 10.1038/ nature05487.
-
(2006)
Nature
, vol.444
, pp. 875-880
-
-
Van Gaal, L.F.1
Mertens, I.L.2
De Block, C.E.3
-
283
-
-
77953393648
-
Endothelial dysfunction in diabetes mellitus: Molecular mechanisms and clinical implications
-
Tabit CE, Chung WB, Hamburg NM, Vita JA. Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications. Rev Endocr Metab Disord. 2010;11:61-74. doi: 10.1007/ s11154-010-9134-4.
-
(2010)
Rev Endocr Metab Disord
, vol.11
, pp. 61-74
-
-
Tabit, C.E.1
Chung, W.B.2
Hamburg, N.M.3
Vita, J.A.4
-
284
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
Furukawa S, Fujita T, Shimabukuro M, Iwaki M, Yamada Y, Nakajima Y, Nakayama O, Makishima M, Matsuda M, Shimomura I. Increased oxidative stress in obesity and its impact on metabolic syndrome. J Clin Invest. 2004;114:1752-1761. doi: 10.1172/JCI21625.
-
(2004)
J Clin Invest
, vol.114
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
285
-
-
5644248079
-
Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes
-
Robertson RP. Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes. J Biol Chem. 2004;279:42351-42354. doi: 10.1074/jbc.R400019200.
-
(2004)
J Biol Chem
, vol.279
, pp. 42351-42354
-
-
Robertson, R.P.1
-
286
-
-
0034455878
-
Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes
-
Mohanty P, Hamouda W, Garg R, Aljada A, Ghanim H, Dandona P. Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes. J Clin Endocrinol Metab. 2000;85:2970-2973. doi: 10.1210/jcem.85.8.6854.
-
(2000)
J Clin Endocrinol Metab
, vol.85
, pp. 2970-2973
-
-
Mohanty, P.1
Hamouda, W.2
Garg, R.3
Aljada, A.4
Ghanim, H.5
Dandona, P.6
-
287
-
-
0033765672
-
High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells
-
Inoguchi T, Li P, Umeda F, Yu HY, Kakimoto M, Imamura M, Aoki T, Etoh T, Hashimoto T, Naruse M, Sano H, Utsumi H, Nawata H. High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C-dependent activation of NAD(P)H oxidase in cultured vascular cells. Diabetes. 2000;49:1939-1945.
-
(2000)
Diabetes
, vol.49
, pp. 1939-1945
-
-
Inoguchi, T.1
Li, P.2
Umeda, F.3
Yu, H.Y.4
Kakimoto, M.5
Imamura, M.6
Aoki, T.7
Etoh, T.8
Hashimoto, T.9
Naruse, M.10
Sano, H.11
Utsumi, H.12
Nawata, H.13
-
288
-
-
0030837996
-
High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells
-
Cosentino F, Hishikawa K, Katusic ZS, Lüscher TF. High glucose increases nitric oxide synthase expression and superoxide anion generation in human aortic endothelial cells. Circulation. 1997;96:25-28.
-
(1997)
Circulation
, vol.96
, pp. 25-28
-
-
Cosentino, F.1
Hishikawa, K.2
Katusic, Z.S.3
Lüscher, T.F.4
-
289
-
-
0029002394
-
Impaired activation of glucose oxidation and NADPH supply in human endothelial cells exposed to H2O2 in high-glucose medium
-
Asahina T, Kashiwagi A, Nishio Y, Ikebuchi M, Harada N, Tanaka Y, Takagi Y, Saeki Y, Kikkawa R, Shigeta Y. Impaired activation of glucose oxidation and NADPH supply in human endothelial cells exposed to H2O2 in high-glucose medium. Diabetes. 1995;44:520-526.
-
(1995)
Diabetes
, vol.44
, pp. 520-526
-
-
Asahina, T.1
Kashiwagi, A.2
Nishio, Y.3
Ikebuchi, M.4
Harada, N.5
Tanaka, Y.6
Takagi, Y.7
Saeki, Y.8
Kikkawa, R.9
Shigeta, Y.10
-
290
-
-
84864210978
-
Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes
-
Paneni F, Mocharla P, Akhmedov A, Costantino S, Osto E, Volpe M, Lüscher TF, Cosentino F. Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes. Circ Res. 2012;111:278-289. doi: 10.1161/CIRCRESAHA.112.266593.
-
(2012)
Circ Res
, vol.111
, pp. 278-289
-
-
Paneni, F.1
Mocharla, P.2
Akhmedov, A.3
Costantino, S.4
Osto, E.5
Volpe, M.6
Lüscher, T.F.7
Cosentino, F.8
-
291
-
-
34548134851
-
Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus
-
Xu J, Wu Y, Song P, Zhang M, Wang S, Zou MH. Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus. Circulation. 2007;116:944-953. doi: 10.1161/CIRCULATIONAHA.106.684795.
-
(2007)
Circulation
, vol.116
, pp. 944-953
-
-
Xu, J.1
Wu, Y.2
Song, P.3
Zhang, M.4
Wang, S.5
Zou, M.H.6
-
292
-
-
85013059184
-
Sirtuin1-regulated lysine acetylation of p66shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction
-
Kumar S, Kim YR, Vikram A, Naqvi A, Li Q, Kassan M, Kumar V, Bachschmid MM, Jacobs JS, Kumar A, Irani K. Sirtuin1-regulated lysine acetylation of p66shc governs diabetes-induced vascular oxidative stress and endothelial dysfunction. Proc Natl Acad Sci USA. 2017;114:1714-1719.
-
(2017)
Proc Natl Acad Sci USA
, vol.114
, pp. 1714-1719
-
-
Kumar, S.1
Kim, Y.R.2
Vikram, A.3
Naqvi, A.4
Li, Q.5
Kassan, M.6
Kumar, V.7
Bachschmid, M.M.8
Jacobs, J.S.9
Kumar, A.10
Irani, K.11
-
293
-
-
84863217619
-
Reactive oxygen species signaling facilitates FOXO-3a/FBXO-dependent vascular BK channel β1 subunit degradation in diabetic mice
-
Lu T, Chai Q, Yu L, d'Uscio LV, Katusic ZS, He T, Lee HC. Reactive oxygen species signaling facilitates FOXO-3a/FBXO-dependent vascular BK channel β1 subunit degradation in diabetic mice. Diabetes. 2012;61:1860-1868. doi: 10.2337/db11-1658.
-
(2012)
Diabetes
, vol.61
, pp. 1860-1868
-
-
Lu, T.1
Chai, Q.2
Yu, L.3
D'Uscio, L.V.4
Katusic, Z.S.5
He, T.6
Lee, H.C.7
-
294
-
-
34250858839
-
Reactive oxygen species-selective regulation of aortic inflammatory gene expression in type 2 diabetes
-
San Martín A, Du P, Dikalova A, Lassègue B, Aleman M, Góngora MC, Brown K, Joseph G, Harrison DG, Taylor WR, Jo H, Griendling KK. Reactive oxygen species-selective regulation of aortic inflammatory gene expression in type 2 diabetes. Am J Physiol Heart Circ Physiol. 2007;292:H2073-H2082. doi: 10.1152/ajpheart.00943.2006.
-
(2007)
Am J Physiol Heart Circ Physiol
, vol.292
, pp. H2073-H2082
-
-
San Martín, A.1
Du, P.2
Dikalova, A.3
Lassègue, B.4
Aleman, M.5
Góngora, M.C.6
Brown, K.7
Joseph, G.8
Harrison, D.G.9
Taylor, W.R.10
Jo, H.11
Griendling, K.K.12
-
295
-
-
84885595820
-
Crucial roles of Nox2-derived oxidative stress in deteriorating the function of insulin receptors and endothelium in dietary obesity of middle-aged mice
-
Du J, Fan LM, Mai A, Li JM. Crucial roles of Nox2-derived oxidative stress in deteriorating the function of insulin receptors and endothelium in dietary obesity of middle-aged mice. Br J Pharmacol. 2013;170:1064-1077. doi: 10.1111/bph.12336.
-
(2013)
Br J Pharmacol
, vol.170
, pp. 1064-1077
-
-
Du, J.1
Fan, L.M.2
Mai, A.3
Li, J.M.4
-
296
-
-
85029550037
-
Genetic deletion of NADPH oxidase 1 rescues microvascular function in mice with metabolic disease
-
Thompson JA, Larion S, Mintz JD, Belin de Chantemèle EJ, Fulton DJ, Stepp DW. Genetic deletion of NADPH oxidase 1 rescues microvascular function in mice with metabolic disease. Circ Res. 2017;121:502-511. doi: 10.1161/CIRCRESAHA.116.309965.
-
(2017)
Circ Res
, vol.121
, pp. 502-511
-
-
Thompson, J.A.1
Larion, S.2
Mintz, J.D.3
Belin De Chantemèle, E.J.4
Fulton, D.J.5
Stepp, D.W.6
-
297
-
-
84900523078
-
Enhanced p22phox expression impairs vascular function through p38 and ERK1/2 MAP kinase-dependent mechanisms in type 2 diabetic mice
-
Kassan M, Choi SK, Galán M, Lee YH, Trebak M, Matrougui K. Enhanced p22phox expression impairs vascular function through p38 and ERK1/2 MAP kinase-dependent mechanisms in type 2 diabetic mice. Am J Physiol Heart Circ Physiol. 2014;306:H972-H980. doi: 10.1152/ajpheart.00872.2013.
-
(2014)
Am J Physiol Heart Circ Physiol
, vol.306
, pp. H972-H980
-
-
Kassan, M.1
Choi, S.K.2
Galán, M.3
Lee, Y.H.4
Trebak, M.5
Matrougui, K.6
-
298
-
-
84876569255
-
Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction
-
Sukumar P, Viswambharan H, Imrie H, et al. Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction. Diabetes. 2013;62:2130-2134. doi: 10.2337/db12-1294.
-
(2013)
Diabetes
, vol.62
, pp. 2130-2134
-
-
Sukumar, P.1
Viswambharan, H.2
Imrie, H.3
-
299
-
-
33846194559
-
Tumor necrosis factor-alpha induces endothelial dysfunction in Lepr(db) mice
-
Gao X, Belmadani S, Picchi A, Xu X, Potter BJ, Tewari-Singh N, Capobianco S, Chilian WM, Zhang C. Tumor necrosis factor-alpha induces endothelial dysfunction in Lepr(db) mice. Circulation. 2007;115:245-254. doi: 10.1161/CIRCULATIONAHA.106.650671.
-
(2007)
Circulation
, vol.115
, pp. 245-254
-
-
Gao, X.1
Belmadani, S.2
Picchi, A.3
Xu, X.4
Potter, B.J.5
Tewari-Singh, N.6
Capobianco, S.7
Chilian, W.M.8
Zhang, C.9
-
300
-
-
33847077963
-
Glucose down-regulation of cGMP-dependent protein kinase I expression in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species
-
Liu S, Ma X, Gong M, Shi L, Lincoln T, Wang S. Glucose down-regulation of cGMP-dependent protein kinase I expression in vascular smooth muscle cells involves NAD(P)H oxidase-derived reactive oxygen species. Free Radic Biol Med. 2007;42:852-863. doi: 10.1016/j. freeradbiomed.2006.12.025.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 852-863
-
-
Liu, S.1
Ma, X.2
Gong, M.3
Shi, L.4
Lincoln, T.5
Wang, S.6
-
301
-
-
84555188779
-
Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells
-
Xi G, Shen X, Maile LA, Wai C, Gollahon K, Clemmons DR. Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells. Diabetes. 2012;61:104-113. doi: 10.2337/ db11-0990.
-
(2012)
Diabetes
, vol.61
, pp. 104-113
-
-
Xi, G.1
Shen, X.2
Maile, L.A.3
Wai, C.4
Gollahon, K.5
Clemmons, D.R.6
-
302
-
-
84878408065
-
Recruitment of Nox4 to a plasma membrane scaffold is required for localized reactive oxygen species generation and sustained Src activation in response to insulin-like growth factor-I
-
Xi G, Shen XC, Wai C, Clemmons DR. Recruitment of Nox4 to a plasma membrane scaffold is required for localized reactive oxygen species generation and sustained Src activation in response to insulin-like growth factor-I. J Biol Chem. 2013;288:15641-15653. doi: 10.1074/jbc. M113.456046.
-
(2013)
J Biol Chem
, vol.288
, pp. 15641-15653
-
-
Xi, G.1
Shen, X.C.2
Wai, C.3
Clemmons, D.R.4
-
303
-
-
33746641678
-
NADPH oxidase-derived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes
-
Ebrahimian TG, Heymes C, You D, Blanc-Brude O, Mees B, Waeckel L, Duriez M, Vilar J, Brandes RP, Levy BI, Shah AM, Silvestre JS. NADPH oxidase-derived overproduction of reactive oxygen species impairs postischemic neovascularization in mice with type 1 diabetes. Am J Pathol. 2006;169:719-728. doi: 10.2353/ajpath.2006.060042.
-
(2006)
Am J Pathol
, vol.169
, pp. 719-728
-
-
Ebrahimian, T.G.1
Heymes, C.2
You, D.3
Blanc-Brude, O.4
Mees, B.5
Waeckel, L.6
Duriez, M.7
Vilar, J.8
Brandes, R.P.9
Levy, B.I.10
Shah, A.M.11
Silvestre, J.S.12
-
304
-
-
34447309095
-
Oxidant stress impairs in vivo reendothelial-ization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: Restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone
-
Sorrentino SA, Bahlmann FH, Besler C, Müller M, Schulz S, Kirchhoff N, Doerries C, Horváth T, Limbourg A, Limbourg F, Fliser D, Haller H, Drexler H, Landmesser U. Oxidant stress impairs in vivo reendothelial-ization capacity of endothelial progenitor cells from patients with type 2 diabetes mellitus: restoration by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone. Circulation. 2007;116:163-173. doi: 10.1161/CIRCULATIONAHA.106.684381.
-
(2007)
Circulation
, vol.116
, pp. 163-173
-
-
Sorrentino, S.A.1
Bahlmann, F.H.2
Besler, C.3
Müller, M.4
Schulz, S.5
Kirchhoff, N.6
Doerries, C.7
Horváth, T.8
Limbourg, A.9
Limbourg, F.10
Fliser, D.11
Haller, H.12
Drexler, H.13
Landmesser, U.14
-
306
-
-
77449142258
-
Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands
-
Yao D, Brownlee M. Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands. Diabetes. 2010;59:249-255. doi: 10.2337/ db09-0801.
-
(2010)
Diabetes
, vol.59
, pp. 249-255
-
-
Yao, D.1
Brownlee, M.2
-
307
-
-
0034996659
-
Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE
-
Wautier MP, Chappey O, Corda S, Stern DM, Schmidt AM, Wautier JL. Activation of NADPH oxidase by AGE links oxidant stress to altered gene expression via RAGE. Am J Physiol Endocrinol Metab. 2001;280:E685-E694. doi: 10.1152/ajpendo.2001.280.5.E685.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
, pp. E685-E694
-
-
Wautier, M.P.1
Chappey, O.2
Corda, S.3
Stern, D.M.4
Schmidt, A.M.5
Wautier, J.L.6
-
308
-
-
85019041258
-
Advanced glycation end-products decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells
-
Ren X, Ren L, Wei Q, Shao H, Chen L, Liu N. Advanced glycation end-products decreases expression of endothelial nitric oxide synthase through oxidative stress in human coronary artery endothelial cells. Cardiovasc Diabetol. 2017;16:52. doi: 10.1186/s12933-017-0531-9.
-
(2017)
Cardiovasc Diabetol
, vol.16
, pp. 52
-
-
Ren, X.1
Ren, L.2
Wei, Q.3
Shao, H.4
Chen, L.5
Liu, N.6
-
309
-
-
84988489916
-
Advanced glycation end-products induce apoptosis of vascular smooth muscle cells: A mechanism for vascular calcification
-
Koike S, Yano S, Tanaka S, Sheikh AM, Nagai A, Sugimoto T. Advanced glycation end-products induce apoptosis of vascular smooth muscle cells: a mechanism for vascular calcification. Int J Mol Sci. 2016;17:1567.
-
(2016)
Int J Mol Sci
, vol.17
, pp. 1567
-
-
Koike, S.1
Yano, S.2
Tanaka, S.3
Sheikh, A.M.4
Nagai, A.5
Sugimoto, T.6
-
310
-
-
85047691537
-
Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells
-
Du X, Matsumura T, Edelstein D, Rossetti L, Zsengellér Z, Szabó C, Brownlee M. Inhibition of GAPDH activity by poly(ADP-ribose) polymerase activates three major pathways of hyperglycemic damage in endothelial cells. J Clin Invest. 2003;112:1049-1057. doi: 10.1172/ JCI18127.
-
(2003)
J Clin Invest
, vol.112
, pp. 1049-1057
-
-
Du, X.1
Matsumura, T.2
Edelstein, D.3
Rossetti, L.4
Zsengellér, Z.5
Szabó, C.6
Brownlee, M.7
-
311
-
-
77955509429
-
Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes
-
Makino A, Scott BT, Dillmann WH. Mitochondrial fragmentation and superoxide anion production in coronary endothelial cells from a mouse model of type 1 diabetes. Diabetologia. 2010;53:1783-1794. doi: 10.1007/s00125-010-1770-4.
-
(2010)
Diabetologia
, vol.53
, pp. 1783-1794
-
-
Makino, A.1
Scott, B.T.2
Dillmann, W.H.3
-
312
-
-
46749156297
-
Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species
-
Yu T, Sheu SS, Robotham JL, Yoon Y. Mitochondrial fission mediates high glucose-induced cell death through elevated production of reactive oxygen species. Cardiovasc Res. 2008;79:341-351. doi: 10.1093/cvr/cvn104.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 341-351
-
-
Yu, T.1
Sheu, S.S.2
Robotham, J.L.3
Yoon, Y.4
-
313
-
-
78650895891
-
High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission
-
Yu T, Jhun BS, Yoon Y. High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission. Antioxid Redox Signal. 2011;14:425-437. doi: 10.1089/ars.2010.3284.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 425-437
-
-
Yu, T.1
Jhun, B.S.2
Yoon, Y.3
-
314
-
-
79961021186
-
Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus
-
Shenouda SM, Widlansky ME, Chen K, et al. Altered mitochondrial dynamics contributes to endothelial dysfunction in diabetes mellitus. Circulation. 2011;124:444-453. doi: 10.1161/ CIRCULATIONAHA.110.014506.
-
(2011)
Circulation
, vol.124
, pp. 444-453
-
-
Shenouda, S.M.1
Widlansky, M.E.2
Chen, K.3
-
315
-
-
84960354785
-
Dynamin-related protein inhibitor downregulates reactive oxygen species levels to indirectly suppress high glucose-induced hyperproliferation of vascular smooth muscle cells
-
Maimaitijiang A, Zhuang X, Jiang X, Li Y. Dynamin-related protein inhibitor downregulates reactive oxygen species levels to indirectly suppress high glucose-induced hyperproliferation of vascular smooth muscle cells. Biochem Biophys Res Commun. 2016;471:474-478. doi: 10.1016/j.bbrc.2016.02.051.
-
(2016)
Biochem Biophys Res Commun
, vol.471
, pp. 474-478
-
-
Maimaitijiang, A.1
Zhuang, X.2
Jiang, X.3
Li, Y.4
-
316
-
-
85014447139
-
Dynamin-related protein 1 mediates low glucose-induced endothelial dysfunction in human arterioles
-
Tanner MJ, Wang J, Ying R, Suboc TB, Malik M, Couillard A, Branum A, Puppala V, Widlansky ME. Dynamin-related protein 1 mediates low glucose-induced endothelial dysfunction in human arterioles. Am J Physiol Heart Circ Physiol. 2017;312:H515-H527. doi: 10.1152/ ajpheart.00499.2016.
-
(2017)
Am J Physiol Heart Circ Physiol
, vol.312
, pp. H515-H527
-
-
Tanner, M.J.1
Wang, J.2
Ying, R.3
Suboc, T.B.4
Malik, M.5
Couillard, A.6
Branum, A.7
Puppala, V.8
Widlansky, M.E.9
-
317
-
-
84973889965
-
Inhibition of mitochondrial fission and NOX2 expression prevent NLRP3 inflammasome activation in the endothelium: The role of corosolic acid action in the amelioration of endothelial dysfunction
-
Li Y, Zhou ZH, Chen MH, Yang J, Leng J, Cao GS, Xin GZ, Liu LF, Kou JP, Liu BL, Li P, Wen XD. Inhibition of mitochondrial fission and NOX2 expression prevent NLRP3 inflammasome activation in the endothelium: the role of corosolic acid action in the amelioration of endothelial dysfunction. Antioxid Redox Signal. 2016;24:893-908. doi: 10.1089/ars.2015.6479.
-
(2016)
Antioxid Redox Signal
, vol.24
, pp. 893-908
-
-
Li, Y.1
Zhou, Z.H.2
Chen, M.H.3
Yang, J.4
Leng, J.5
Cao, G.S.6
Xin, G.Z.7
Liu, L.F.8
Kou, J.P.9
Liu, B.L.10
Li, P.11
Wen, X.D.12
-
318
-
-
84950104119
-
Heart disease and stroke statistics-2016 update: A report from the American Heart Association
-
Mozaffarian D, Benjamin EJ, Go AS, et al; Writing Group Members; American Heart Association Statistics Committee; Stroke Statistics Subcommittee. Heart disease and stroke statistics-2016 update: a report from the American Heart Association. Circulation. 2016;133:e38-e360. doi: 10.1161/CIR.0000000000000350.
-
(2016)
Circulation
, vol.133
, pp. e38-e360
-
-
Mozaffarian, D.1
Benjamin, E.J.2
Go, A.S.3
-
319
-
-
77955014011
-
Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study
-
O'Donnell MJ, Xavier D, Liu L, et al; INTERSTROKE investigators. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): a case-control study. Lancet. 2010;376:112-123. doi: 10.1016/S0140-6736(10)60834-3.
-
(2010)
Lancet
, vol.376
, pp. 112-123
-
-
O'Donnell, M.J.1
Xavier, D.2
Liu, L.3
-
320
-
-
77952675659
-
Pathophysiologic mechanisms of acute ischemic stroke: An overview with emphasis on therapeutic significance beyond thrombolysis
-
Deb P, Sharma S, Hassan KM. Pathophysiologic mechanisms of acute ischemic stroke: an overview with emphasis on therapeutic significance beyond thrombolysis. Pathophysiology. 2010;17:197-218. doi: 10.1016/j.pathophys.2009.12.001.
-
(2010)
Pathophysiology
, vol.17
, pp. 197-218
-
-
Deb, P.1
Sharma, S.2
Hassan, K.M.3
-
322
-
-
77950261039
-
Oxidative stress after thrombolysis-induced reperfusion in human stroke
-
Domínguez C, Delgado P, Vilches A, Martín-Gallán P, Ribó M, Santamarina E, Molina C, Corbeto N, Rodríguez-Sureda V, Rosell A, Alvarez-Sabín J, Montaner J. Oxidative stress after thrombolysis-induced reperfusion in human stroke. Stroke. 2010;41:653-660. doi: 10.1161/STROKEAHA.109.571935.
-
(2010)
Stroke
, vol.41
, pp. 653-660
-
-
Domínguez, C.1
Delgado, P.2
Vilches, A.3
Martín-Gallán, P.4
Ribó, M.5
Santamarina, E.6
Molina, C.7
Corbeto, N.8
Rodríguez-Sureda, V.9
Rosell, A.10
Alvarez-Sabín, J.11
Montaner, J.12
-
323
-
-
77956808539
-
Post-stroke inhibition of induced nadph oxidase type 4 prevents oxidative stress and neurodegeneration
-
Kleinschnitz C, Grund H, Wingler K, et al. Post-stroke inhibition of induced nadph oxidase type 4 prevents oxidative stress and neurodegeneration. PLoS Biol. 2010;8:e1000479.
-
(2010)
PLoS Biol
, vol.8
, pp. e1000479
-
-
Kleinschnitz, C.1
Grund, H.2
Wingler, K.3
-
324
-
-
0028040278
-
Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia
-
Yang G, Chan PH, Chen J, Carlson E, Chen SF, Weinstein P, Epstein CJ, Kamii H. Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia. Stroke. 1994;25:165-170.
-
(1994)
Stroke
, vol.25
, pp. 165-170
-
-
Yang, G.1
Chan, P.H.2
Chen, J.3
Carlson, E.4
Chen, S.F.5
Weinstein, P.6
Epstein, C.J.7
Kamii, H.8
-
325
-
-
84872486948
-
Molecular mechanisms of ischemia-reperfusion injury in brain: Pivotal role of the mitochondrial membrane potential in reactive oxygen species generation
-
Sanderson TH, Reynolds CA, Kumar R, Przyklenk K, Hüttemann M. Molecular mechanisms of ischemia-reperfusion injury in brain: pivotal role of the mitochondrial membrane potential in reactive oxygen species generation. Mol Neurobiol. 2013;47:9-23. doi: 10.1007/s12035-012-8344-z.
-
(2013)
Mol Neurobiol
, vol.47
, pp. 9-23
-
-
Sanderson, T.H.1
Reynolds, C.A.2
Kumar, R.3
Przyklenk, K.4
Hüttemann, M.5
-
326
-
-
0036192957
-
Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: Implications for the production and role of superoxide radicals
-
Kim GW, Kondo T, Noshita N, Chan PH. Manganese superoxide dismutase deficiency exacerbates cerebral infarction after focal cerebral ischemia/reperfusion in mice: implications for the production and role of superoxide radicals. Stroke. 2002;33:809-815.
-
(2002)
Stroke
, vol.33
, pp. 809-815
-
-
Kim, G.W.1
Kondo, T.2
Noshita, N.3
Chan, P.H.4
-
327
-
-
0033135367
-
Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice
-
Fujimura M, Morita-Fujimura Y, Kawase M, Copin JC, Calagui B, Epstein CJ, Chan PH. Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome C and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J Neurosci. 1999;19:3414-3422.
-
(1999)
J Neurosci
, vol.19
, pp. 3414-3422
-
-
Fujimura, M.1
Morita-Fujimura, Y.2
Kawase, M.3
Copin, J.C.4
Calagui, B.5
Epstein, C.J.6
Chan, P.H.7
-
328
-
-
85019092634
-
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia
-
Hernansanz-Agustín P, Ramos E, Navarro E, Parada E, Sánchez-López N, Peláez-Aguado L, Cabrera-García JD, Tello D, Buendia I, Marina A, Egea J, López MG, Bogdanova A, Martínez-Ruiz A. Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia. Redox Biol. 2017;12:1040-1051. doi: 10.1016/j.redox.2017.04.025.
-
(2017)
Redox Biol
, vol.12
, pp. 1040-1051
-
-
Hernansanz-Agustín, P.1
Ramos, E.2
Navarro, E.3
Parada, E.4
Sánchez-López, N.5
Peláez-Aguado, L.6
Cabrera-García, J.D.7
Tello, D.8
Buendia, I.9
Marina, A.10
Egea, J.11
López, M.G.12
Bogdanova, A.13
Martínez-Ruiz, A.14
-
329
-
-
84857508603
-
The oxygen free radicals originating from mitochondrial complex I contribute to oxidative brain injury following hypoxia-ischemia in neonatal mice
-
Niatsetskaya ZV, Sosunov SA, Matsiukevich D, Utkina-Sosunova IV, Ratner VI, Starkov AA, Ten VS. The oxygen free radicals originating from mitochondrial complex I contribute to oxidative brain injury following hypoxia-ischemia in neonatal mice. J Neurosci. 2012;32:3235-3244. doi: 10.1523/JNEUROSCI.6303-11.2012.
-
(2012)
J Neurosci
, vol.32
, pp. 3235-3244
-
-
Niatsetskaya, Z.V.1
Sosunov, S.A.2
Matsiukevich, D.3
Utkina-Sosunova, I.V.4
Ratner, V.I.5
Starkov, A.A.6
Ten, V.S.7
-
330
-
-
84902322007
-
Mitochondrial reactive oxygen species: A double edged sword in ischemia/reperfusion vs preconditioning
-
Kalogeris T, Bao Y, Korthuis RJ. Mitochondrial reactive oxygen species: a double edged sword in ischemia/reperfusion vs preconditioning. Redox Biol. 2014;2:702-714. doi: 10.1016/j.redox.2014.05.006.
-
(2014)
Redox Biol
, vol.2
, pp. 702-714
-
-
Kalogeris, T.1
Bao, Y.2
Korthuis, R.J.3
-
331
-
-
84894533962
-
Monoamine oxidase-A knockdown in human neuroblastoma cells reveals protection against mitochondrial toxins
-
Fitzgerald JC, Ugun-Klusek A, Allen G, De Girolamo LA, Hargreaves I, Ufer C, Abramov AY, Billett EE. Monoamine oxidase-A knockdown in human neuroblastoma cells reveals protection against mitochondrial toxins. FASEB J. 2014;28:218-229. doi: 10.1096/fj.13-235481.
-
(2014)
FASEB J
, vol.28
, pp. 218-229
-
-
Fitzgerald, J.C.1
Ugun-Klusek, A.2
Allen, G.3
De Girolamo, L.A.4
Hargreaves, I.5
Ufer, C.6
Abramov, A.Y.7
Billett, E.E.8
-
332
-
-
84872200721
-
Deletion of the ageing gene p66(Shc) reduces early stroke size following ischaemia/reperfusion brain injury
-
Spescha RD, Shi Y, Wegener S, Keller S, Weber B, Wyss MM, Lauinger N, Tabatabai G, Paneni F, Cosentino F, Hock C, Weller M, Nitsch RM, Lüscher TF, Camici GG. Deletion of the ageing gene p66(Shc) reduces early stroke size following ischaemia/reperfusion brain injury. Eur Heart J. 2013;34:96-103. doi: 10.1093/eurheartj/ehs331.
-
(2013)
Eur Heart J
, vol.34
, pp. 96-103
-
-
Spescha, R.D.1
Shi, Y.2
Wegener, S.3
Keller, S.4
Weber, B.5
Wyss, M.M.6
Lauinger, N.7
Tabatabai, G.8
Paneni, F.9
Cosentino, F.10
Hock, C.11
Weller, M.12
Nitsch, R.M.13
Lüscher, T.F.14
Camici, G.G.15
-
333
-
-
84937213794
-
Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke
-
Spescha RD, Klohs J, Semerano A, et al. Post-ischaemic silencing of p66Shc reduces ischaemia/reperfusion brain injury and its expression correlates to clinical outcome in stroke. Eur Heart J. 2015;36:1590-1600. doi: 10.1093/eurheartj/ehv140.
-
(2015)
Eur Heart J
, vol.36
, pp. 1590-1600
-
-
Spescha, R.D.1
Klohs, J.2
Semerano, A.3
-
334
-
-
0030663253
-
Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase
-
Walder CE, Green SP, Darbonne WC, Mathias J, Rae J, Dinauer MC, Curnutte JT, Thomas GR. Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase. Stroke. 1997;28:2252-2258.
-
(1997)
Stroke
, vol.28
, pp. 2252-2258
-
-
Walder, C.E.1
Green, S.P.2
Darbonne, W.C.3
Mathias, J.4
Rae, J.5
Dinauer, M.C.6
Curnutte, J.T.7
Thomas, G.R.8
-
335
-
-
67649852282
-
Inhibition of NADPH oxidase is neuro-protective after ischemia-reperfusion
-
Chen H, Song YS, Chan PH. Inhibition of NADPH oxidase is neuro-protective after ischemia-reperfusion. J Cereb Blood Flow Metab. 2009;29:1262-1272. doi: 10.1038/jcbfm.2009.47.
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 1262-1272
-
-
Chen, H.1
Song, Y.S.2
Chan, P.H.3
-
336
-
-
35649015344
-
NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke
-
Kahles T, Luedike P, Endres M, Galla HJ, Steinmetz H, Busse R, Neumann-Haefelin T, Brandes RP. NADPH oxidase plays a central role in blood-brain barrier damage in experimental stroke. Stroke. 2007;38:3000-3006. doi: 10.1161/STROKEAHA.107.489765.
-
(2007)
Stroke
, vol.38
, pp. 3000-3006
-
-
Kahles, T.1
Luedike, P.2
Endres, M.3
Galla, H.J.4
Steinmetz, H.5
Busse, R.6
Neumann-Haefelin, T.7
Brandes, R.P.8
-
337
-
-
85033668469
-
NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage
-
Casas AI, Geuss E, Kleikers PWM, Mencl S, Herrmann AM, Buendia I, Egea J, Meuth SG, Lopez MG, Kleinschnitz C, Schmidt HHHW. NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage. Proc Natl Acad Sci USA. 2017;114:12315-12320.
-
(2017)
Proc Natl Acad Sci USA
, vol.114
, pp. 12315-12320
-
-
Casas, A.I.1
Geuss, E.2
Kleikers, P.W.M.3
Mencl, S.4
Herrmann, A.M.5
Buendia, I.6
Egea, J.7
Meuth, S.G.8
Lopez, M.G.9
Kleinschnitz, C.10
Schmidt, H.H.H.W.11
-
338
-
-
79151470304
-
Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats
-
Genovese T, Mazzon E, Paterniti I, Esposito E, Bramanti P, Cuzzocrea S. Modulation of NADPH oxidase activation in cerebral ischemia/reperfusion injury in rats. Brain Res. 2011;1372:92-102. doi: 10.1016/j. brainres.2010.11.088.
-
(2011)
Brain Res
, vol.1372
, pp. 92-102
-
-
Genovese, T.1
Mazzon, E.2
Paterniti, I.3
Esposito, E.4
Bramanti, P.5
Cuzzocrea, S.6
-
339
-
-
84923875879
-
Glutathione suppresses cerebral infarct volume and cell death after ischemic injury: Involvement of FOXO3 inactivation and Bcl2 expression
-
Song J, Park J, Oh Y, Lee JE. Glutathione suppresses cerebral infarct volume and cell death after ischemic injury: involvement of FOXO3 inactivation and Bcl2 expression. Oxid Med Cell Longev. 2015;2015:426069. doi: 10.1155/2015/426069.
-
(2015)
Oxid Med Cell Longev
, vol.2015
, pp. 426069
-
-
Song, J.1
Park, J.2
Oh, Y.3
Lee, J.E.4
-
340
-
-
79954628624
-
NADPH oxidase is involved in post-ischemic brain inflammation
-
Chen H, Kim GS, Okami N, Narasimhan P, Chan PH. NADPH oxidase is involved in post-ischemic brain inflammation. Neurobiol Dis. 2011;42:341-348. doi: 10.1016/j.nbd.2011.01.027.
-
(2011)
Neurobiol Dis
, vol.42
, pp. 341-348
-
-
Chen, H.1
Kim, G.S.2
Okami, N.3
Narasimhan, P.4
Chan, P.H.5
-
341
-
-
84884393430
-
NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotox-icity in experimental stroke
-
Wang Z, Wei X, Liu K, Zhang X, Yang F, Zhang H, He Y, Zhu T, Li F, Shi W, Zhang Y, Xu H, Liu J, Yi F. NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotox-icity in experimental stroke. Free Radic Biol Med. 2013;65:942-951. doi: 10.1016/j.freeradbiomed.2013.08.166.
-
(2013)
Free Radic Biol Med
, vol.65
, pp. 942-951
-
-
Wang, Z.1
Wei, X.2
Liu, K.3
Zhang, X.4
Yang, F.5
Zhang, H.6
He, Y.7
Zhu, T.8
Li, F.9
Shi, W.10
Zhang, Y.11
Xu, H.12
Liu, J.13
Yi, F.14
-
342
-
-
84910595333
-
Nox2 knockout delays infarct progression and increases vascular recovery through angiogenesis in mice following ischaemic stroke with reperfusion
-
McCann SK, Dusting GJ, Roulston CL. Nox2 knockout delays infarct progression and increases vascular recovery through angiogenesis in mice following ischaemic stroke with reperfusion. PLoS One. 2014;9:e110602. doi: 10.1371/journal.pone.0110602.
-
(2014)
PLoS One
, vol.9
, pp. e110602
-
-
McCann, S.K.1
Dusting, G.J.2
Roulston, C.L.3
-
343
-
-
84867582890
-
Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression
-
Kim HA, Brait VH, Lee S, De Silva TM, Diep H, Eisenhardt A, Drummond GR, Sobey CG. Brain infarct volume after permanent focal ischemia is not dependent on Nox2 expression. Brain Res. 2012;1483:105-111. doi: 10.1016/j.brainres.2012.09.023.
-
(2012)
Brain Res
, vol.1483
, pp. 105-111
-
-
Kim, H.A.1
Brait, V.H.2
Lee, S.3
De Silva, T.M.4
Diep, H.5
Eisenhardt, A.6
Drummond, G.R.7
Sobey, C.G.8
-
344
-
-
84973322290
-
Detrimental role of pericyte Nox4 in the acute phase of brain ischemia
-
Nishimura A, Ago T, Kuroda J, Arimura K, Tachibana M, Nakamura K, Wakisaka Y, Sadoshima J, Iihara K, Kitazono T. Detrimental role of pericyte Nox4 in the acute phase of brain ischemia. J Cereb Blood Flow Metab. 2016;36:1143-1154. doi: 10.1177/0271678X15606456.
-
(2016)
J Cereb Blood Flow Metab
, vol.36
, pp. 1143-1154
-
-
Nishimura, A.1
Ago, T.2
Kuroda, J.3
Arimura, K.4
Tachibana, M.5
Nakamura, K.6
Wakisaka, Y.7
Sadoshima, J.8
Iihara, K.9
Kitazono, T.10
-
345
-
-
77955844394
-
NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice
-
Kahles T, Kohnen A, Heumueller S, Rappert A, Bechmann I, Liebner S, Wittko IM, Neumann-Haefelin T, Steinmetz H, Schroeder K, Brandes RP. NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice. Neurobiol Dis. 2010;40:185-192. doi: 10.1016/j.nbd.2010.05.023.
-
(2010)
Neurobiol Dis
, vol.40
, pp. 185-192
-
-
Kahles, T.1
Kohnen, A.2
Heumueller, S.3
Rappert, A.4
Bechmann, I.5
Liebner, S.6
Wittko, I.M.7
Neumann-Haefelin, T.8
Steinmetz, H.9
Schroeder, K.10
Brandes, R.P.11
-
346
-
-
84921992664
-
Role of neuronal NADPH oxidase 1 in the peri-infarct regions after stroke
-
Choi DH, Kim JH, Lee KH, Kim HY, Kim YS, Choi WS, Lee J. Role of neuronal NADPH oxidase 1 in the peri-infarct regions after stroke. PLoS One. 2015;10:e0116814. doi: 10.1371/journal.pone.0116814.
-
(2015)
PLoS One
, vol.10
, pp. e0116814
-
-
Choi, D.H.1
Kim, J.H.2
Lee, K.H.3
Kim, H.Y.4
Kim, Y.S.5
Choi, W.S.6
Lee, J.7
-
347
-
-
67849088501
-
Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke
-
Jackman KA, Miller AA, Drummond GR, Sobey CG. Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke. Brain Res. 2009;1286:215-220. doi: 10.1016/j.brainres.2009.06.056.
-
(2009)
Brain Res
, vol.1286
, pp. 215-220
-
-
Jackman, K.A.1
Miller, A.A.2
Drummond, G.R.3
Sobey, C.G.4
-
348
-
-
37149029659
-
Diabetes, the metabolic syndrome, and ischemic stroke: Epidemiology and possible mechanisms
-
Air EL, Kissela BM. Diabetes, the metabolic syndrome, and ischemic stroke: epidemiology and possible mechanisms. Diabetes Care. 2007;30:3131-3140. doi: 10.2337/dc06-1537.
-
(2007)
Diabetes Care
, vol.30
, pp. 3131-3140
-
-
Air, E.L.1
Kissela, B.M.2
-
349
-
-
84895607012
-
Hyperglycemia, acute ischemic stroke, and thrombolytic therapy
-
Hafez S, Coucha M, Bruno A, Fagan SC, Ergul A. Hyperglycemia, acute ischemic stroke, and thrombolytic therapy. Transl Stroke Res. 2014;5:442-453. doi: 10.1007/s12975-014-0336-z.
-
(2014)
Transl Stroke Res
, vol.5
, pp. 442-453
-
-
Hafez, S.1
Coucha, M.2
Bruno, A.3
Fagan, S.C.4
Ergul, A.5
-
350
-
-
58149268010
-
Glucose and NADPH oxidase drive neuronal superoxide formation in stroke
-
Suh SW, Shin BS, Ma H, Van Hoecke M, Brennan AM, Yenari MA, Swanson RA. Glucose and NADPH oxidase drive neuronal superoxide formation in stroke. Ann Neurol. 2008;64:654-663. doi: 10.1002/ana.21511.
-
(2008)
Ann Neurol
, vol.64
, pp. 654-663
-
-
Suh, S.W.1
Shin, B.S.2
Ma, H.3
Van Hoecke, M.4
Brennan, A.M.5
Yenari, M.A.6
Swanson, R.A.7
-
351
-
-
84862202961
-
Importance of mitochondrial dynamin-related protein 1 in hypothalamic glucose sensitivity in rats
-
Carneiro L, Allard C, Guissard C, Fioramonti X, Tourrel-Cuzin C, Bailbé D, Barreau C, Offer G, Nédelec E, Salin B, Rigoulet M, Belenguer P, Pénicaud L, Leloup C. Importance of mitochondrial dynamin-related protein 1 in hypothalamic glucose sensitivity in rats. Antioxid Redox Signal. 2012;17:433-444. doi: 10.1089/ars.2011.4254.
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 433-444
-
-
Carneiro, L.1
Allard, C.2
Guissard, C.3
Fioramonti, X.4
Tourrel-Cuzin, C.5
Bailbé, D.6
Barreau, C.7
Offer, G.8
Nédelec, E.9
Salin, B.10
Rigoulet, M.11
Belenguer, P.12
Pénicaud, L.13
Leloup, C.14
-
352
-
-
84905388716
-
Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: The role of inhibition of Drp1 in ischemic brain damage
-
Zuo W, Zhang S, Xia CY, Guo XF, He WB, Chen NH. Mitochondria autophagy is induced after hypoxic/ischemic stress in a Drp1 dependent manner: the role of inhibition of Drp1 in ischemic brain damage. Neuropharmacology. 2014;86:103-115. doi: 10.1016/j. neuropharm.2014.07.002.
-
(2014)
Neuropharmacology
, vol.86
, pp. 103-115
-
-
Zuo, W.1
Zhang, S.2
Xia, C.Y.3
Guo, X.F.4
He, W.B.5
Chen, N.H.6
-
353
-
-
78049481928
-
Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines
-
Haines BA, Mehta SL, Pratt SM, Warden CH, Li PA. Deletion of mitochondrial uncoupling protein-2 increases ischemic brain damage after transient focal ischemia by altering gene expression patterns and enhancing inflammatory cytokines. J Cereb Blood Flow Metab. 2010;30:1825-1833. doi: 10.1038/jcbfm.2010.52.
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 1825-1833
-
-
Haines, B.A.1
Mehta, S.L.2
Pratt, S.M.3
Warden, C.H.4
Li, P.A.5
-
354
-
-
84959420767
-
UCP2 regulates mitochondrial fission and ventromedial nucleus control of glucose responsiveness
-
Toda C, Kim JD, Impellizzeri D, Cuzzocrea S, Liu ZW, Diano S. UCP2 regulates mitochondrial fission and ventromedial nucleus control of glucose responsiveness. Cell. 2016;164:872-883. doi: 10.1016/j.cell.2016.02.010.
-
(2016)
Cell
, vol.164
, pp. 872-883
-
-
Toda, C.1
Kim, J.D.2
Impellizzeri, D.3
Cuzzocrea, S.4
Liu, Z.W.5
Diano, S.6
-
355
-
-
0041464712
-
Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma
-
Mattiasson G, Shamloo M, Gido G, Mathi K, Tomasevic G, Yi S, Warden CH, Castilho RF, Melcher T, Gonzalez-Zulueta M, Nikolich K, Wieloch T. Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma. Nat Med. 2003;9:1062-1068. doi: 10.1038/nm903.
-
(2003)
Nat Med
, vol.9
, pp. 1062-1068
-
-
Mattiasson, G.1
Shamloo, M.2
Gido, G.3
Mathi, K.4
Tomasevic, G.5
Yi, S.6
Warden, C.H.7
Castilho, R.F.8
Melcher, T.9
Gonzalez-Zulueta, M.10
Nikolich, K.11
Wieloch, T.12
-
356
-
-
84957934688
-
Deletion or inhibition of the oxygen sensor PHD1 protects against ischemic stroke via reprogramming of neuronal metabolism
-
Quaegebeur A, Segura I, Schmieder R, et al. Deletion or inhibition of the oxygen sensor PHD1 protects against ischemic stroke via reprogramming of neuronal metabolism. Cell Metab. 2016;23:280-291. doi: 10.1016/j.cmet.2015.12.007.
-
(2016)
Cell Metab
, vol.23
, pp. 280-291
-
-
Quaegebeur, A.1
Segura, I.2
Schmieder, R.3
-
357
-
-
84876283769
-
Peroxiredoxin 2 battles poly(ADP-ribose) polymerase 1- And p53-de-pendent prodeath pathways after ischemic injury
-
Leak RK, Zhang L, Luo Y, Li P, Zhao H, Liu X, Ling F, Jia J, Chen J, Ji X. Peroxiredoxin 2 battles poly(ADP-ribose) polymerase 1- and p53-de-pendent prodeath pathways after ischemic injury. Stroke. 2013;44:1124-1134. doi: 10.1161/STROKEAHA.111.680157.
-
(2013)
Stroke
, vol.44
, pp. 1124-1134
-
-
Leak, R.K.1
Zhang, L.2
Luo, Y.3
Li, P.4
Zhao, H.5
Liu, X.6
Ling, F.7
Jia, J.8
Chen, J.9
Ji, X.10
-
358
-
-
79955770424
-
Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo
-
Jin RC, Mahoney CE, Coleman Anderson L, Ottaviano F, Croce K, Leopold JA, Zhang YY, Tang SS, Handy DE, Loscalzo J. Glutathione peroxidase-3 deficiency promotes platelet-dependent thrombosis in vivo. Circulation. 2011;123:1963-1973. doi: 10.1161/ CIRCULATIONAHA.110.000034.
-
(2011)
Circulation
, vol.123
, pp. 1963-1973
-
-
Jin, R.C.1
Mahoney, C.E.2
Coleman Anderson, L.3
Ottaviano, F.4
Croce, K.5
Leopold, J.A.6
Zhang, Y.Y.7
Tang, S.S.8
Handy, D.E.9
Loscalzo, J.10
-
359
-
-
0037203261
-
Glutathione peroxidase inhibits cell death and glial activation following experimental stroke
-
Ishibashi N, Prokopenko O, Weisbrot-Lefkowitz M, Reuhl KR, Mirochnitchenko O. Glutathione peroxidase inhibits cell death and glial activation following experimental stroke. Brain Res Mol Brain Res. 2002;109:34-44.
-
(2002)
Brain Res Mol Brain Res
, vol.109
, pp. 34-44
-
-
Ishibashi, N.1
Prokopenko, O.2
Weisbrot-Lefkowitz, M.3
Reuhl, K.R.4
Mirochnitchenko, O.5
-
360
-
-
0034744739
-
Overexpression of copper-zinc superoxide dismutase attenuates acute activation of activator protein-1 after transient focal cerebral ischemia in mice
-
Huang CY, Fujimura M, Chang YY, Chan PH. Overexpression of copper-zinc superoxide dismutase attenuates acute activation of activator protein-1 after transient focal cerebral ischemia in mice. Stroke. 2001;32:741-747.
-
(2001)
Stroke
, vol.32
, pp. 741-747
-
-
Huang, C.Y.1
Fujimura, M.2
Chang, Y.Y.3
Chan, P.H.4
-
361
-
-
43049180323
-
Why have antioxidants failed in clinical trials?
-
Steinhubl SR. Why have antioxidants failed in clinical trials? Am J Cardiol. 2008;101:14D-19D. doi: 10.1016/j.amjcard.2008.02.003.
-
(2008)
Am J Cardiol
, vol.101
, pp. 14D-19D
-
-
Steinhubl, S.R.1
-
362
-
-
33847378451
-
Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis
-
Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA. 2007;297:842-857. doi: 10.1001/jama.297.8.842.
-
(2007)
JAMA
, vol.297
, pp. 842-857
-
-
Bjelakovic, G.1
Nikolova, D.2
Gluud, L.L.3
Simonetti, R.G.4
Gluud, C.5
-
363
-
-
18844397807
-
Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries
-
Lucchesi PA, Belmadani S, Matrougui K. Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries. J Hypertens. 2005;23:571-579.
-
(2005)
J Hypertens
, vol.23
, pp. 571-579
-
-
Lucchesi, P.A.1
Belmadani, S.2
Matrougui, K.3
-
364
-
-
67649249930
-
Reactive oxygen species as cardiovascular mediators: Lessons from endothelial-specific protein overexpression mouse models
-
Suvorava T, Kojda G. Reactive oxygen species as cardiovascular mediators: lessons from endothelial-specific protein overexpression mouse models. Biochim Biophys Acta. 2009;1787:802-810. doi: 10.1016/j. bbabio.2009.04.005.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 802-810
-
-
Suvorava, T.1
Kojda, G.2
-
365
-
-
33646359238
-
Reactive oxygen species: Influence on cerebral vascular tone
-
Faraci FM. Reactive oxygen species: influence on cerebral vascular tone. J Appl Physiol (1985). 2006;100:739-743. doi: 10.1152/ japplphysiol.01044.2005.
-
(2006)
J Appl Physiol (1985)
, vol.100
, pp. 739-743
-
-
Faraci, F.M.1
-
366
-
-
84876931396
-
Beyond oxidative stress: An immunologist's guide to reactive oxygen species
-
Nathan C, Cunningham-Bussel A. Beyond oxidative stress: an immunologist's guide to reactive oxygen species. Nat Rev Immunol. 2013;13:349-361. doi: 10.1038/nri3423.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 349-361
-
-
Nathan, C.1
Cunningham-Bussel, A.2
-
367
-
-
84924911735
-
Reactive oxygen species: Physiological roles in the regulation of vascular cells
-
Vara D, Pula G. Reactive oxygen species: physiological roles in the regulation of vascular cells. Curr Mol Med. 2014;14:1103-1125.
-
(2014)
Curr Mol Med
, vol.14
, pp. 1103-1125
-
-
Vara, D.1
Pula, G.2
-
368
-
-
84994165662
-
Therapeutic potential of NADPH oxidase ¼ inhibitors
-
Teixeira G, Szyndralewiez C, Molango S, Carnesecchi S, Heitz F, Wiesel P, Wood JM. Therapeutic potential of NADPH oxidase ¼ inhibitors. Br J Pharmacol. 2017;174:1647-1669. doi: 10.1111/bph.13532.
-
(2017)
Br J Pharmacol
, vol.174
, pp. 1647-1669
-
-
Teixeira, G.1
Szyndralewiez, C.2
Molango, S.3
Carnesecchi, S.4
Heitz, F.5
Wiesel, P.6
Wood, J.M.7
|