Hydrogen peroxide activates NF-κB through tyrosine phosphorylation of IκBα and serine phosphorylation of p65. Evidence for the involvement of IκBα kinase and Syk protein-tyrosine kinase

Journal of Biological Chemistry

Volumn 278, Issue 26, 2003, Pages 24233-24241

  Takada, Yasunari ^a   Mukhopadhyay, Asok ^a,d   Kundu, Gopal C ^b   Mahabeleshwar, Ganapati H ^b   Singh, Sujay ^c   Aggarwal, Bharat B ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b NATIONAL CENTRE FOR CELL SCIENCE   (India)

^c Imgenex Corporation   (United States)

^d NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

BIODEGRADATION; CELLS; ENZYME INHIBITION; HYDROGEN PEROXIDE; PHOSPHORUS;

PHOSPHORYLATION;

PROTEINS;

HYDROGEN PEROXIDE; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; N ACETYLLEUCYLLEUCYLNORLEUCINAL; PROTEASOME; PROTEIN KINASE SYK; PROTEIN SUBUNIT; PROTEIN TYROSINE KINASE; SERINE; SYNAPTOTAGMIN; TYROSINE; UNCLASSIFIED DRUG;

ARTICLE; BONE MARROW CELL; CONCENTRATION RESPONSE; DISSOCIATION; ENZYME MECHANISM; GENE ACTIVATION; HUMAN; HUMAN CELL; NUCLEAR IMPORT; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN TRANSPORT; TIME; TRANSCRIPTION INITIATION;

ACTIVE TRANSPORT, CELL NUCLEUS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME PRECURSORS; HUMANS; HYDROGEN PEROXIDE; I-KAPPA B PROTEINS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KINETICS; NF-KAPPA B; PHOSPHORYLATION; PROTEIN-TYROSINE KINASES; SERINE; TRANSCRIPTION FACTOR RELA; TUMOR CELLS, CULTURED; TUMOR NECROSIS FACTOR-ALPHA; TYROSINE;

EID: 0037591401     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212389200     Document Type: Article

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