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Volumn 62, Issue 6, 2013, Pages 2130-2134

Nox2 NADPH oxidase has a critical role in insulin resistance-related endothelial cell dysfunction

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; GP91DS TAT FUSION PROTEIN; HYBRID PROTEIN; OXIDOREDUCTASE INHIBITOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SMALL INTERFERING RNA; SUPEROXIDE; UNCLASSIFIED DRUG;

EID: 84876569255     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db12-1294     Document Type: Article
Times cited : (112)

References (18)
  • 1
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • DOI 10.1038/nature05482, PII NATURE05482
    • Kahn SE, Hull RL, Utzschneider KM. Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 2006;444:840-846 (Pubitemid 46024990)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 2
    • 33745400514 scopus 로고    scopus 로고
    • Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: A population-based retrospective cohort study
    • DOI 10.1016/S0140-6736(06)68967-8, PII S0140673606689678
    • Booth GL, Kapral MK, Fung K, Tu JV. Relation between age and cardiovascular disease in men and women with diabetes compared with non-diabetic people: a population-based retrospective cohort study. Lancet 2006;368:29-36 (Pubitemid 43947203)
    • (2006) Lancet , vol.368 , Issue.9529 , pp. 29-36
    • Booth, G.L.1    Kapral, M.K.2    Fung, K.3    Tu, J.V.4
  • 3
    • 0034634281 scopus 로고    scopus 로고
    • Endothelial dysfunction in cardiovascular diseases: The role of oxidant stress
    • Cai H, Harrison DG. Endothelial dysfunction in cardiovascular diseases: the role of oxidant stress. Circ Res 2000;87:840-844
    • (2000) Circ Res , vol.87 , pp. 840-844
    • Cai, H.1    Harrison, D.G.2
  • 4
    • 2442421194 scopus 로고    scopus 로고
    • Is Oxidative Stress the Pathogenic Mechanism Underlying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited
    • DOI 10.1161/01.ATV.0000122852.22604.78
    • Ceriello A, Motz E. Is oxidative stress the pathogenic mechanism underlying insulin resistance, diabetes, and cardiovascular disease? The common soil hypothesis revisited. Arterioscler Thromb Vasc Biol 2004;24:816-823 (Pubitemid 38620857)
    • (2004) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.24 , Issue.5 , pp. 816-823
    • Ceriello, A.1    Motz, E.2
  • 6
    • 58149328550 scopus 로고    scopus 로고
    • Effect of endothelium-specific insulin resistance on endothelial function in vivo
    • Duncan ER, Crossey PA, Walker S, et al. Effect of endothelium-specific insulin resistance on endothelial function in vivo. Diabetes 2008;57:3307-3314
    • (2008) Diabetes , vol.57 , pp. 3307-3314
    • Duncan, E.R.1    Crossey, P.A.2    Walker, S.3
  • 7
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: Physiology and pathophysiology
    • DOI 10.1152/physrev.00044.2005
    • Bedard K, Krause KH. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol Rev 2007;87:245-313 (Pubitemid 46209993)
    • (2007) Physiological Reviews , vol.87 , Issue.1 , pp. 245-313
    • Bedard, K.1    Krause, K.-H.2
  • 8
    • 79957890939 scopus 로고    scopus 로고
    • Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets
    • Drummond GR, Selemidis S, Griendling KK, Sobey CG. Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets. Nat Rev Drug Discov 2011;10:453-471
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 453-471
    • Drummond, G.R.1    Selemidis, S.2    Griendling, K.K.3    Sobey, C.G.4
  • 9
    • 84865487544 scopus 로고    scopus 로고
    • Novel role of the IGF-1 receptor in endothelial function and repair: Studies in endothelium-targeted IGF-1 receptor transgenic mice
    • Imrie H, Viswambharan H, Sukumar P, et al. Novel role of the IGF-1 receptor in endothelial function and repair: studies in endothelium-targeted IGF-1 receptor transgenic mice. Diabetes 2012;61:2359-2368
    • (2012) Diabetes , vol.61 , pp. 2359-2368
    • Imrie, H.1    Viswambharan, H.2    Sukumar, P.3
  • 10
    • 0035980160 scopus 로고    scopus 로고
    • - and systolic blood pressure in mice
    • Rey FE, Cifuentes ME, Kiarash A, Quinn MT, Pagano PJ. Novel competitive inhibitor of NAD(P)H oxidase assembly attenuates vascular O(2)(-) and systolic blood pressure in mice. Circ Res 2001;89:408-414 (Pubitemid 34132656)
    • (2001) Circulation Research , vol.89 , Issue.5 , pp. 408-414
    • Rey, F.E.1    Cifuentes, M.E.2    Kiarash, A.3    Quinn, M.T.4    Pagano, P.J.5
  • 11
    • 79957517872 scopus 로고    scopus 로고
    • Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo
    • Ray R, Murdoch CE, Wang M, et al. Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo. Arterioscler Thromb Vasc Biol 2011;31:1368-1376
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 1368-1376
    • Ray, R.1    Murdoch, C.E.2    Wang, M.3
  • 12
    • 33646843042 scopus 로고    scopus 로고
    • + Redox State Increases NAD(P)H Oxidase Activity in Cultured Rat Vascular Smooth Muscle Cells
    • DOI 10.1016/j.amjhyper.2005.11.017, PII S0895706106001087
    • Yang M, Kahn AM. Insulin-stimulated NADH/NAD+ redox state increases NAD(P)H oxidase activity in cultured rat vascular smooth muscle cells. Am J Hypertens 2006;19:587-592 (Pubitemid 43775851)
    • (2006) American Journal of Hypertension , vol.19 , Issue.6 , pp. 587-592
    • Yang, M.1    Kahn, A.M.2
  • 14
    • 78149239505 scopus 로고    scopus 로고
    • NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis
    • Zhang M, Brewer AC, Schröder K, et al. NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis. Proc Natl Acad Sci USA 2010;107:18121-18126
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 18121-18126
    • Zhang, M.1    Brewer, A.C.2    Schröder, K.3
  • 15
    • 15944384240 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase has divergent effects on vascular and metabolic function in obesity
    • DOI 10.2337/diabetes.54.4.1082
    • Noronha BT, Li JM, Wheatcroft SB, Shah AM, Kearney MT. Inducible nitric oxide synthase has divergent effects on vascular and metabolic function in obesity. Diabetes 2005;54:1082-1089 (Pubitemid 40446322)
    • (2005) Diabetes , vol.54 , Issue.4 , pp. 1082-1089
    • Noronha, B.T.1    Li, J.-M.2    Wheatcroft, S.B.3    Shall, A.M.4    Kearney, M.T.5
  • 16
    • 33846862034 scopus 로고    scopus 로고
    • Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47phox expression and evidence of endothelial oxidative stress
    • DOI 10.1161/CIRCULATIONAHA.106.657486, PII 0000301720070206000014
    • Silver AE, Beske SD, Christou DD, et al. Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress. Circulation 2007;115:627-637 (Pubitemid 46226173)
    • (2007) Circulation , vol.115 , Issue.5 , pp. 627-637
    • Silver, A.E.1    Beske, S.D.2    Christou, D.D.3    Donato, A.J.4    Moreau, K.L.5    Eskurza, I.6    Gates, P.E.7    Seals, D.R.8
  • 17
    • 0037046214 scopus 로고    scopus 로고
    • Mechanisms of increased vascular superoxide production in human diabetes mellitus: Role of NAD(P)H oxidase and endothelial nitric oxide synthase
    • DOI 10.1161/01.CIR.0000012748.58444.08
    • Guzik TJ, Mussa S, Gastaldi D, et al. Mechanisms of increased vascular superoxide production in human diabetes mellitus: role of NAD(P)H oxidase and endothelial nitric oxide synthase. Circulation 2002;105:1656-1662 (Pubitemid 34298608)
    • (2002) Circulation , vol.105 , Issue.14 , pp. 1656-1662
    • Guzik, T.J.1    Mussa, S.2    Gastaldi, D.3    Sadowski, J.4    Ratnatunga, C.5    Pillai, R.6    Channon, K.M.7
  • 18
    • 33646525680 scopus 로고    scopus 로고
    • Vascular NADPH oxidases as drug targets for novel antioxidant strategies
    • Guzik TJ, Harrison DG. Vascular NADPH oxidases as drug targets for novel antioxidant strategies. Drug Discov Today 2006;11:524-533
    • (2006) Drug Discov Today , vol.11 , pp. 524-533
    • Guzik, T.J.1    Harrison, D.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.