NOX2 deficiency ameliorates cerebral injury through reduction of complexin II-mediated glutamate excitotoxicity in experimental stroke

Free Radical Biology and Medicine

Volumn 65, Issue , 2013, Pages 942-951

  Wang, Ziying ^a   Wei, Xinbing ^a   Liu, Kang ^a   Zhang, Xiumei ^a   Yang, Fan ^a   Zhang, Hongyu ^b   He, Yeteng ^a   Zhu, Tianfeng ^a   Li, Fengli ^a   Shi, Weichen ^a   Zhang, Yan ^a   Xu, Huiyan ^a   Liu, Jiang ^a   Yi, Fan ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Cerebral ischemia injury; Complexin; Free radicals; NADPH oxidase; SNARE complex

Indexed keywords

GLUTAMIC ACID; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SNARE PROTEIN; SUCCINATE DEHYDROGENASE (UBIQUINONE); COMPLEXIN I; COMPLEXIN II; CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; NERVE PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CELL CULTURE; BRAIN CORTEX; BRAIN HOMOGENATE; BRAIN INFARCTION SIZE; BRAIN INJURY; BRAIN ISCHEMIA; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME DEFICIENCY; EXCITOTOXICITY; FLOW CYTOMETRY; GENE SILENCING; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NONHUMAN; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL CULTURE; CEREBRAL ARTERY DISEASE; ENZYMOLOGY; GENETICS; HIPPOCAMPUS; KNOCKOUT MOUSE; MALE; METABOLISM; NECROSIS; OXIDATIVE STRESS; PATHOLOGY; PHYSIOLOGY;

MUS;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; ASTROCYTES; CELLS, CULTURED; GLUTAMIC ACID; HIPPOCAMPUS; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MEMBRANE GLYCOPROTEINS; MICE, KNOCKOUT; NADPH OXIDASE; NECROSIS; NERVE TISSUE PROTEINS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84884393430     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2013.08.166     Document Type: Article

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