NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 34, Issue 11, 2014, Pages 2413-2420

  Kigawa, Yasuyoshi ^a,c   Miyazaki, Takuro ^a   Lei, Xiao Feng ^a   Nakamachi, Tomoya ^b,c,d   Oguchi, Tatsunori ^a   Kim Kaneyama, Joo Ri ^a   Taniyama, Matsuo ^b   Tsunawaki, Shohko ^a   Shioda, Seiji ^b   Miyazaki, Akira ^a  

^a SHOWA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHOWA UNIVERSITY   (Japan)

^c SHOWA UNIVERSITY FUJIGAOKA HOSPITAL   (Japan)

^d UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Aortic aneurysm, abdominal; Cytokines; Macrophages; NADPH oxidase; Oxidative stress

Indexed keywords

ANGIOTENSIN II; GAMMA INTERFERON; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 4; JANUS KINASE; MACROPHAGE ELASTASE; MESSENGER RNA; NEUTRALIZING ANTIBODY; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; ANTIBODY; CYBB PROTEIN, MOUSE; MEMBRANE PROTEIN; MMP9 PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ABDOMINAL AORTA ANEURYSM; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; BONE MARROW TRANSPLANTATION; CELL ISOLATION; CELLULAR SECRETION; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE EXACERBATION; EXPERIMENTAL MODEL; GENE TARGETING; HEMATOPOIETIC STEM CELL; IMMUNOHISTOCHEMISTRY; MOUSE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PERITONEUM MACROPHAGE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; DRUG EFFECTS; GENETICS; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; PATHOLOGY;

ANGIOTENSIN II; ANIMALS; ANTIBODIES; AORTIC ANEURYSM, ABDOMINAL; DISEASE MODELS, ANIMAL; INTERLEUKIN-1BETA; MACROPHAGES; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASE 9; MEMBRANE GLYCOPROTEINS; MICE; MICE, KNOCKOUT; NADPH OXIDASE; REACTIVE OXYGEN SPECIES;

EID: 84911878872     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.114.303086     Document Type: Article

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