메뉴 건너뛰기




Volumn 52, Issue 2, 2012, Pages 348-356

Mitochondrial fission in endothelial cells after simulated ischemia/reperfusion: Role of nitric oxide and reactive oxygen species

Author keywords

Dynamin related protein 1; Endothelial cell; Free radicals; Hypoxia reoxygenation; Ischemia reperfusion; Mitochondrial fission; Mitochondrial superoxide; Nitric oxide; Shear stress

Indexed keywords

ANTIOXIDANT; DYNAMIN I; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE;

EID: 84855462583     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.10.491     Document Type: Article
Times cited : (100)

References (74)
  • 1
    • 0034053099 scopus 로고    scopus 로고
    • Pathophysiology of ischaemia-reperfusion injury
    • DOI 10.1002/(SICI)1096-9896(200002)190:3<255::AID-PATH526>3.0.CO;2- 6
    • D.L. Carden, and D.N. Granger Pathophysiology of ischaemia-reperfusion injury J. Pathol. 190 2000 255 266 (Pubitemid 30141372)
    • (2000) Journal of Pathology , vol.190 , Issue.3 , pp. 255-266
    • Carden, D.L.1    Granger, D.N.2
  • 2
    • 0025542037 scopus 로고
    • Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat
    • P.S. Tsao, N. Aoki, D.J. Lefer, G. Johnson III, and A.M. Lefer Time course of endothelial dysfunction and myocardial injury during myocardial ischemia and reperfusion in the cat Circulation 82 1990 1402 1412
    • (1990) Circulation , vol.82 , pp. 1402-1412
    • Tsao, P.S.1    Aoki, N.2    Lefer, D.J.3    Johnson Iii, G.4    Lefer, A.M.5
  • 3
    • 0028946762 scopus 로고
    • Physiologic mechanisms of post-ischemic tissue injury
    • D.N. Granger, and R.J. Korthuis Physiologic mechanisms of post-ischemic tissue injury Annu. Rev. Physiol. 57 1995 311 332
    • (1995) Annu. Rev. Physiol. , vol.57 , pp. 311-332
    • Granger, D.N.1    Korthuis, R.J.2
  • 4
    • 30444439216 scopus 로고    scopus 로고
    • The discovery of nitric oxide and its role in vascular biology
    • S. Moncada, and E.A. Higgs The discovery of nitric oxide and its role in vascular biology Br. J. Pharmacol. 147 Suppl. 1 2006 S193 S201
    • (2006) Br. J. Pharmacol. , vol.147 , Issue.SUPPL. 1
    • Moncada, S.1    Higgs, E.A.2
  • 6
    • 0028865420 scopus 로고
    • Nitric oxide: An important signaling mechanism between vascular endothelium and parenchymal cells in the regulation of oxygen consumption
    • W. Shen, T.H. Hintze, and M.S. Wolin Nitric oxide: an important signaling mechanism between vascular endothelium and parenchymal cells in the regulation of oxygen consumption Circulation 92 1995 3505 3512
    • (1995) Circulation , vol.92 , pp. 3505-3512
    • Shen, W.1    Hintze, T.H.2    Wolin, M.S.3
  • 7
    • 28044464985 scopus 로고
    • Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide: Implications for neurodegenerative diseases
    • M.W. Cleeter, J.M. Cooper, V.M. Darley-Usmar, S. Moncada, and A.H. Schapira Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide: implications for neurodegenerative diseases FEBS Lett. 345 1994 50 54
    • (1994) FEBS Lett. , vol.345 , pp. 50-54
    • Cleeter, M.W.1    Cooper, J.M.2    Darley-Usmar, V.M.3    Moncada, S.4    Schapira, A.H.5
  • 8
    • 0029986691 scopus 로고    scopus 로고
    • Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles
    • DOI 10.1006/abbi.1996.0146
    • J.J. Poderoso, M.C. Carreras, C. Lisdero, N. Riobo, F. Schopfer, and A. Boveris Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles Arch. Biochem. Biophys. 328 1996 85 92 (Pubitemid 26108173)
    • (1996) Archives of Biochemistry and Biophysics , vol.328 , Issue.1 , pp. 85-92
    • Poderoso, J.J.1    Carreras, M.C.2    Lisdero, C.3    Riobo, N.4    Schopfer, F.5    Boveris, A.6
  • 10
    • 0037293568 scopus 로고    scopus 로고
    • Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning
    • DOI 10.1038/sj.bjp.0705080
    • P. Ferdinandy, and R. Schulz Nitric oxide, superoxide, and peroxynitrite in myocardial ischaemia-reperfusion injury and preconditioning Br. J. Pharmacol. 138 2003 532 543 (Pubitemid 36315301)
    • (2003) British Journal of Pharmacology , vol.138 , Issue.4 , pp. 532-543
    • Ferdinandy, P.1    Schulz, R.2
  • 11
    • 33646055216 scopus 로고    scopus 로고
    • The role of oxidants and free radicals in reperfusion injury
    • J.L. Zweier, and M.A. Talukder The role of oxidants and free radicals in reperfusion injury Cardiovasc. Res. 70 2006 181 190
    • (2006) Cardiovasc. Res. , vol.70 , pp. 181-190
    • Zweier, J.L.1    Talukder, M.A.2
  • 13
    • 0141738708 scopus 로고    scopus 로고
    • Role of the mitochondrial permeability transition in apoptotic and necrotic death after ischemia/reperfusion injury to hepatocytes
    • DOI 10.2174/1566524033479564
    • J.S. Kim, L. He, T. Qian, and J.J. Lemasters Role of the mitochondrial permeability transition in apoptotic and necrotic death after ischemia/reperfusion injury to hepatocytes Curr. Mol. Med. 3 2003 527 535 (Pubitemid 37173382)
    • (2003) Current Molecular Medicine , vol.3 , Issue.6 , pp. 527-535
    • Kim, J.-S.1    He, L.2    Qian, T.3    Lemasters, J.J.4
  • 14
    • 38849156952 scopus 로고    scopus 로고
    • Heart mitochondria: Gates of life and death
    • DOI 10.1093/cvr/cvm005
    • A.B. Gustafsson, and R.A. Gottlieb Heart mitochondria: gates of life and death Cardiovasc. Res. 77 2008 334 343 (Pubitemid 351197632)
    • (2008) Cardiovascular Research , vol.77 , Issue.2 , pp. 334-343
    • Gustafsson, A.B.1    Gottlieb, R.A.2
  • 15
    • 0037023636 scopus 로고    scopus 로고
    • Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury
    • DOI 10.1161/01.RES.0000015224.07870.9A
    • T.M. Scarabelli, A. Stephanou, E. Pasini, L. Comini, R. Raddino, R.A. Knight, and D.S. Latchman Different signaling pathways induce apoptosis in endothelial cells and cardiac myocytes during ischemia/reperfusion injury Circ. Res. 90 2002 745 748 (Pubitemid 34640895)
    • (2002) Circulation Research , vol.90 , Issue.6 , pp. 745-748
    • Scarabelli, T.M.1    Stephanou, A.2    Pasini, E.3    Comini, L.4    Raddino, R.5    Knight, R.A.6    Latchman, D.S.7
  • 16
    • 4544378532 scopus 로고    scopus 로고
    • Mitochondrial fusion intermediates revealed in vitro
    • DOI 10.1126/science.1100612
    • S. Meeusen, J.M. McCaffery, and J. Nunnari Mitochondrial fusion intermediates revealed in vitro Science 305 2004 1747 1752 (Pubitemid 39249636)
    • (2004) Science , vol.305 , Issue.5691 , pp. 1747-1752
    • Meeusen, S.1    McCaffery, J.M.2    Nunnari, J.3
  • 17
    • 22544451586 scopus 로고    scopus 로고
    • Disruption of fusion results in mitochondrial heterogeneity and dysfunction
    • DOI 10.1074/jbc.M503062200
    • H. Chen, A. Chomyn, and D.C. Chan Disruption of fusion results in mitochondrial heterogeneity and dysfunction J. Biol. Chem. 280 2005 26185 26192 (Pubitemid 41022214)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.28 , pp. 26185-26192
    • Chen, H.1    Chomyn, A.2    Chan, D.C.3
  • 18
  • 20
    • 56349133547 scopus 로고    scopus 로고
    • Positioning mitochondrial plasticity within cellular signaling cascades
    • V. Soubannier, and H.M. McBride Positioning mitochondrial plasticity within cellular signaling cascades Biochim. Biophys. Acta 1793 2009 154 170
    • (2009) Biochim. Biophys. Acta , vol.1793 , pp. 154-170
    • Soubannier, V.1    McBride, H.M.2
  • 21
    • 77955273254 scopus 로고    scopus 로고
    • Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics
    • C. Sauvanet, S. Duvezin-Caubet, J.P. di Rago, and M. Rojo Energetic requirements and bioenergetic modulation of mitochondrial morphology and dynamics Semin. Cell Dev. Biol. 21 2009 558 565
    • (2009) Semin. Cell Dev. Biol. , vol.21 , pp. 558-565
    • Sauvanet, C.1    Duvezin-Caubet, S.2    Di Rago, J.P.3    Rojo, M.4
  • 24
    • 65849443539 scopus 로고    scopus 로고
    • Mitochondrial fragmentation is involved in methamphetamine-induced cell death in rat hippocampal neural progenitor cells
    • C. Tian, L.C. Murrin, and J.C. Zheng Mitochondrial fragmentation is involved in methamphetamine-induced cell death in rat hippocampal neural progenitor cells PLoS One 4 2009 e5546
    • (2009) PLoS One , vol.4 , pp. 5546
    • Tian, C.1    Murrin, L.C.2    Zheng, J.C.3
  • 25
  • 28
    • 38849099158 scopus 로고    scopus 로고
    • Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization
    • DOI 10.1016/j.devcel.2007.11.019, PII S1534580707004753
    • A. Cassidy-Stone, J.E. Chipuk, E. Ingerman, C. Song, C. Yoo, T. Kuwana, M.J. Kurth, J.T. Shaw, J.E. Hinshaw, D.R. Green, and J. Nunnari Chemical inhibition of the mitochondrial division dynamin reveals its role in Bax/Bak-dependent mitochondrial outer membrane permeabilization Dev. Cell 14 2008 193 204 (Pubitemid 351189177)
    • (2008) Developmental Cell , vol.14 , Issue.2 , pp. 193-204
    • Cassidy-Stone, A.1    Chipuk, J.E.2    Ingerman, E.3    Song, C.4    Yoo, C.5    Kuwana, T.6    Kurth, M.J.7    Shaw, J.T.8    Hinshaw, J.E.9    Green, D.R.10    Nunnari, J.11
  • 29
    • 76749157966 scopus 로고    scopus 로고
    • MiR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway
    • J. Li, S. Donath, Y. Li, D. Qin, B.S. Prabhakar, and P. Li miR-30 regulates mitochondrial fission through targeting p53 and the dynamin-related protein-1 pathway PLoS Genet. 6 2010 e1000795
    • (2010) PLoS Genet. , vol.6 , pp. 1000795
    • Li, J.1    Donath, S.2    Li, Y.3    Qin, D.4    Prabhakar, B.S.5    Li, P.6
  • 30
    • 34249689057 scopus 로고    scopus 로고
    • Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission
    • DOI 10.1074/jbc.M607279200
    • N. Taguchi, N. Ishihara, A. Jofuku, T. Oka, and K. Mihara Mitotic phosphorylation of dynamin-related GTPase Drp1 participates in mitochondrial fission J. Biol. Chem. 282 2007 11521 11529 (Pubitemid 47100787)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.15 , pp. 11521-11529
    • Taguchi, N.1    Ishihara, N.2    Jofuku, A.3    Oka, T.4    Mihara, K.5
  • 31
    • 1542380494 scopus 로고    scopus 로고
    • Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission
    • DOI 10.1016/S0960-9822(04)00084-3, PII S0960982204000843
    • Z. Harder, R. Zunino, and H. McBride Sumo1 conjugates mitochondrial substrates and participates in mitochondrial fission Curr. Biol. 14 2004 340 345 (Pubitemid 38300214)
    • (2004) Current Biology , vol.14 , Issue.4 , pp. 340-345
    • Harder, Z.1    Zunino, R.2    McBride, H.3
  • 33
    • 34848840991 scopus 로고    scopus 로고
    • Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death
    • DOI 10.1038/sj.embor.7401062, PII 7401062
    • J.T. Cribbs, and S. Strack Reversible phosphorylation of Drp1 by cyclic AMP-dependent protein kinase and calcineurin regulates mitochondrial fission and cell death EMBO Rep. 8 2007 939 944 (Pubitemid 47500477)
    • (2007) EMBO Reports , vol.8 , Issue.10 , pp. 939-944
    • Cribbs, J.T.1    Strack, S.2
  • 34
  • 38
    • 0021972202 scopus 로고
    • Flow effects on prostacyclin production by cultured human endothelial cells
    • J.A. Frangos, S.G. Eskin, L.V. McIntire, and C.L. Ives Flow effects on prostacyclin production in cultured human endothelial cells Science 227 1985 1477 1479 (Pubitemid 15146990)
    • (1985) Science , vol.227 , Issue.4693 , pp. 1477-1479
    • Frangos, J.A.1    Eskin, S.G.2    McIntire, L.V.3    Ives, C.L.4
  • 39
    • 34247214633 scopus 로고    scopus 로고
    • Regulation of antioxidants and phase 2 enzymes by shear-induced reactive oxygen species in endothelial cells
    • DOI 10.1007/s10439-007-9279-9
    • C.I. Jones III, H. Zhu, S.F. Martin, Z. Han, Y. Li, and B.R. Alevriadou Regulation of antioxidants and phase 2 enzymes by shear-induced reactive oxygen species in endothelial cells Ann. Biomed. Eng. 35 2007 683 693 (Pubitemid 46626132)
    • (2007) Annals of Biomedical Engineering , vol.35 , Issue.5 , pp. 683-693
    • Jones III, C.I.1    Zhu, H.2    Martin, S.F.3    Han, Z.4    Li, Y.5    Alevriadou, B.R.6
  • 40
    • 0016710467 scopus 로고
    • Mechanism of the reductive activation of succinate dehydrogenase
    • B.A. Ackrell, E.B. Kearney, and D. Edmondson Mechanism of the reductive activation of succinate dehydrogenase J. Biol. Chem. 250 1975 7114 7119
    • (1975) J. Biol. Chem. , vol.250 , pp. 7114-7119
    • Ackrell, B.A.1    Kearney, E.B.2    Edmondson, D.3
  • 41
    • 79953263796 scopus 로고    scopus 로고
    • Excess NO predisposes mitochondrial succinate-cytochrome c reductase to produce hydroxyl radical
    • J. Chen, C.L. Chen, B.R. Alevriadou, J.L. Zweier, and Y.R. Chen Excess NO predisposes mitochondrial succinate-cytochrome c reductase to produce hydroxyl radical Biochim. Biophys. Acta 1807 2011 491 502
    • (2011) Biochim. Biophys. Acta , vol.1807 , pp. 491-502
    • Chen, J.1    Chen, C.L.2    Alevriadou, B.R.3    Zweier, J.L.4    Chen, Y.R.5
  • 42
    • 77952236126 scopus 로고    scopus 로고
    • Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury
    • S.B. Ong, S. Subrayan, S.Y. Lim, D.M. Yellon, S.M. Davidson, and D.J. Hausenloy Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury Circulation 121 2010 2012 2022
    • (2010) Circulation , vol.121 , pp. 2012-2022
    • Ong, S.B.1    Subrayan, S.2    Lim, S.Y.3    Yellon, D.M.4    Davidson, S.M.5    Hausenloy, D.J.6
  • 43
    • 0345120940 scopus 로고    scopus 로고
    • Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives
    • R.C. Scaduto Jr., and L.W. Grotyohann Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives Biophys. J. 76 1999 469 477 (Pubitemid 29202474)
    • (1999) Biophysical Journal , vol.76 , Issue.1 , pp. 469-477
    • Scaduto Jr., R.C.1    Grotyohann, L.W.2
  • 44
    • 1342289237 scopus 로고    scopus 로고
    • Methods for detection of reactive metabolites of oxygen and nitrogen: In vitro and in vivo considerations
    • M.M. Tarpey, D.A. Wink, and M.B. Grisham Methods for detection of reactive metabolites of oxygen and nitrogen: in vitro and in vivo considerations Am. J. Physiol. Regul. Integr. Comp. Physiol. 286 2004 R431 R444
    • (2004) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.286
    • Tarpey, M.M.1    Wink, D.A.2    Grisham, M.B.3
  • 45
    • 36048945922 scopus 로고    scopus 로고
    • ImageJ for microscopy
    • T.J. Collins ImageJ for microscopy Biotechniques 43 2007 25 30
    • (2007) Biotechniques , vol.43 , pp. 25-30
    • Collins, T.J.1
  • 48
    • 30344453413 scopus 로고    scopus 로고
    • Simultaneous quantitative measurement and automated analysis of mitochondrial morphology, mass, potential, and motility in living human skin fibroblasts
    • DOI 10.1002/cyto.a.20198
    • W.J. Koopman, H.J. Visch, J.A. Smeitink, and P.H. Willems Simultaneous quantitative measurement and automated analysis of mitochondrial morphology, mass, potential, and motility in living human skin fibroblasts Cytometry A 69 2006 1 12 (Pubitemid 43062691)
    • (2006) Cytometry Part A , vol.69 , Issue.1 , pp. 1-12
    • Koopman, W.J.H.1    Visch, H.-J.2    Smeitink, J.A.M.3    Willems, P.H.G.M.4
  • 49
    • 33644552417 scopus 로고    scopus 로고
    • Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology
    • T. Yu, J.L. Robotham, and Y. Yoon Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology Proc. Natl. Acad. Sci. U. S. A. 103 2006 2653 2658
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 2653-2658
    • Yu, T.1    Robotham, J.L.2    Yoon, Y.3
  • 53
    • 20444494969 scopus 로고    scopus 로고
    • Endothelium-derived nitric oxide regulates postischemic myocardial oxygenation and oxygen consumption by modulation of mitochondrial electron transport
    • DOI 10.1161/CIRCULATIONAHA.104.527226
    • X. Zhao, G. He, Y.R. Chen, R.P. Pandian, P. Kuppusamy, and J.L. Zweier Endothelium-derived nitric oxide regulates postischemic myocardial oxygenation and oxygen consumption by modulation of mitochondrial electron transport Circulation 111 2005 2966 2972 (Pubitemid 40814190)
    • (2005) Circulation , vol.111 , Issue.22 , pp. 2966-2972
    • Zhao, X.1    He, G.2    Chen, Y.-R.3    Pandian, R.P.4    Kuppusamy, P.5    Zweier, J.L.6
  • 58
    • 63849133179 scopus 로고    scopus 로고
    • Mitochondria-derived reactive oxygen species mediate heme oxygenase-1 expression in sheared endothelial cells
    • Z. Han, S. Varadharaj, R.J. Giedt, J.L. Zweier, H.H. Szeto, and B.R. Alevriadou Mitochondria-derived reactive oxygen species mediate heme oxygenase-1 expression in sheared endothelial cells J. Pharmacol. Exp. Ther. 329 2009 94 101
    • (2009) J. Pharmacol. Exp. Ther. , vol.329 , pp. 94-101
    • Han, Z.1    Varadharaj, S.2    Giedt, R.J.3    Zweier, J.L.4    Szeto, H.H.5    Alevriadou, B.R.6
  • 59
    • 79955753583 scopus 로고    scopus 로고
    • Regulation of endothelial function by mitochondrial reactive oxygen species
    • M.E. Widlansky, and D.D. Gutterman Regulation of endothelial function by mitochondrial reactive oxygen species Antioxid. Redox Signal. 15 2011 1517 1530
    • (2011) Antioxid. Redox Signal. , vol.15 , pp. 1517-1530
    • Widlansky, M.E.1    Gutterman, D.D.2
  • 61
    • 6344285417 scopus 로고    scopus 로고
    • Endothelial cell superoxide generation: Regulation and relevance for cardiovascular pathophysiology
    • J.M. Li, and A.M. Shah Endothelial cell superoxide generation: regulation and relevance for cardiovascular pathophysiology Am. J. Physiol. Regul. Integr. Comp. Physiol. 287 2004 R1014 R1030
    • (2004) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.287
    • Li, J.M.1    Shah, A.M.2
  • 63
    • 0032475865 scopus 로고    scopus 로고
    • 2 +/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • 2 +/calmodulin-dependent and tetrahydrobiopterin regulatory process J. Biol. Chem. 273 1998 25804 25808
    • (1998) J. Biol. Chem. , vol.273 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 64
    • 46849095596 scopus 로고    scopus 로고
    • Regulation of eNOS-derived superoxide by endogenous methylarginines
    • DOI 10.1021/bi702377a
    • L.J. Druhan, S.P. Forbes, A.J. Pope, C.A. Chen, J.L. Zweier, and A.J. Cardounel Regulation of eNOS-derived superoxide by endogenous methylarginines Biochemistry 47 2008 7256 7263 (Pubitemid 351956374)
    • (2008) Biochemistry , vol.47 , Issue.27 , pp. 7256-7263
    • Druhan, L.J.1    Forbes, S.P.2    Pope, A.J.3    Chen, C.-A.4    Zweier, J.L.5    Cardounel, A.J.6
  • 68
    • 33746299692 scopus 로고    scopus 로고
    • Regulation of mitochondrial morphology through proteolytic cleavage of OPA1
    • DOI 10.1038/sj.emboj.7601184, PII 7601184
    • N. Ishihara, Y. Fujita, T. Oka, and K. Mihara Regulation of mitochondrial morphology through proteolytic cleavage of OPA1 EMBO J. 25 2006 2966 2977 (Pubitemid 44106750)
    • (2006) EMBO Journal , vol.25 , Issue.13 , pp. 2966-2977
    • Ishihara, N.1    Fujita, Y.2    Oka, T.3    Mihara, K.4
  • 69
    • 79959987510 scopus 로고    scopus 로고
    • Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation
    • A.S. Rambold, B. Kostelecky, N. Elia, and J. Lippincott-Schwartz Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation Proc. Natl. Acad. Sci. U. S. A. 108 2011 10190 10195
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 10190-10195
    • Rambold, A.S.1    Kostelecky, B.2    Elia, N.3    Lippincott-Schwartz, J.4
  • 70
    • 64249133725 scopus 로고    scopus 로고
    • S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury
    • D.H. Cho, T. Nakamura, J. Fang, P. Cieplak, A. Godzik, Z. Gu, and S.A. Lipton S-nitrosylation of Drp1 mediates beta-amyloid-related mitochondrial fission and neuronal injury Science 324 2009 102 105
    • (2009) Science , vol.324 , pp. 102-105
    • Cho, D.H.1    Nakamura, T.2    Fang, J.3    Cieplak, P.4    Godzik, A.5    Gu, Z.6    Lipton, S.A.7
  • 71
    • 77956795824 scopus 로고    scopus 로고
    • Mitochondrial morphology and cardiovascular disease
    • S.B. Ong, and D.J. Hausenloy Mitochondrial morphology and cardiovascular disease Cardiovasc. Res. 88 2010 16 29
    • (2010) Cardiovasc. Res. , vol.88 , pp. 16-29
    • Ong, S.B.1    Hausenloy, D.J.2
  • 72
    • 20444461625 scopus 로고    scopus 로고
    • The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system
    • DOI 10.1093/hmg/ddi149
    • S. Pich, D. Bach, P. Briones, M. Liesa, M. Camps, X. Testar, M. Palacin, and A. Zorzano The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system Hum. Mol. Genet. 14 2005 1405 1415 (Pubitemid 40823451)
    • (2005) Human Molecular Genetics , vol.14 , Issue.11 , pp. 1405-1415
    • Pich, S.1    Bach, D.2    Briones, P.3    Liesa, M.4    Camps, M.5    Testar, X.6    Palacin, M.7    Zorzano, A.8
  • 73
    • 1142285456 scopus 로고    scopus 로고
    • Nitric oxide in myocardial ischemia/reperfusion injury
    • DOI 10.1016/j.cardiores.2003.09.019
    • R. Schulz, M. Kelm, and G. Heusch Nitric oxide in myocardial ischemia/reperfusion injury Cardiovasc. Res. 61 2004 402 413 (Pubitemid 38210147)
    • (2004) Cardiovascular Research , vol.61 , Issue.3 , pp. 402-413
    • Schulz, R.1    Kelm, M.2    Heusch, G.3
  • 74
    • 34247598856 scopus 로고    scopus 로고
    • Endothelial mitochondria: Contributing to vascular function and disease
    • DOI 10.1161/01.RES.0000261970.18328.1d, PII 0000301220070427000007
    • S.M. Davidson, and M.R. Duchen Endothelial mitochondria: contributing to vascular function and disease Circ. Res. 100 2007 1128 1141 (Pubitemid 46684126)
    • (2007) Circulation Research , vol.100 , Issue.8 , pp. 1128-1141
    • Davidson, S.M.1    Duchen, M.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.