p47phox is required for atherosclerotic lesion progression in ApoE-/- mice

Journal of Clinical Investigation

Volumn 108, Issue 10, 2001, Pages 1513-1522

  Barry Lane, Patricia A ^a   Patterson, Cam ^b,c   Van Der Merwe, Marié ^b   Hu, Zhaoyong ^a   Holland, Stephen M ^d   Yeh, Edward T H ^e   Runge, Marschall S ^b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^e UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E; GLYCOPROTEIN; GROWTH FACTOR; PROTEIN P47; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROSIS; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; HEART MUSCLE CELL; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; VASCULAR LESION;

ANIMALS; APOLIPOPROTEINS E; ARTERIOSCLEROSIS; BASE SEQUENCE; CELL DIVISION; DISEASE PROGRESSION; DNA PRIMERS; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; NADPH OXIDASE; PHOSPHOPROTEINS; REACTIVE OXYGEN SPECIES;

EID: 0035179016     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI200111927     Document Type: Article

References (46)

1. Free radicals, reactive oxygen species and human disease: A critical evaluation with special reference to atherosclerosis
2. Hypercholesterolemia increases endothelial superoxide anion production
3. Increased accumulation of the glycoxidation product N(epsilon)-(carboxymethyl)lysine in human tissues in diabetes and aging
4. Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation
5. Role of oxidized LDL and antioxidants in atherosclerosis
6. Lipoprotein oxidation is a mediator of atherogenesis: Insights from pharmacological studies
7. The expression of NADPH oxidase components in human glomerular mesangial cells: Detection of protein and mRNA for p47phox, p67phox, and p22phox
8. The functional expression of p47-phox and p67-phox may contribute to the generation of superoxide by an NADPH oxidase-like system in human fibroblasts
9. Identification of a superoxide-generating NADPH oxidase system in human fibroblasts
10. Reactive oxygen species and neutrophil respiratory burst cytochrome b558 are produced by kidney glomerular cells in passive Heymann nephritis
11. NADPH-oxidase expression and in situ production of superoxide by osteoclasts actively resorbing bone
12. The biochemical basis of the NADPH oxidase of phagocytes
13. Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells
14. Superoxide anion release by human endothelial cells: Synergism between a phorbol ester and a calcium ionophore
15. The cytochrome b-558 molecules involved in the fibroblast and polymorphonuclear leucocyte superoxide-generating NADPH oxidase systems are structurally and genetically distinct
16. Activation of the leukocyte NADPH oxidase by phorbol ester requires the phosphorylation of p47PHOX on serine 303 or 304
17. Expression of functional neutrophil-type NADPH oxidase in cultured rat coronary microvascular endothelial cells
18. Expression of phagocyte NADPH oxidase components in human endothelial cells
19. p22phox is a critical component of the superoxide-generating NADH/NADPH oxidase system and regulates angiotensin II-induced hypertrophy in vascular smooth muscle cells
20. Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle
21. Superoxide anion from the adventitia of the rat thoracic aorta inactivates nitric oxide
22. Cytochrome b-558 alpha-subunit cloning and expression in rat aortic smooth muscle cells
23. Cell transformation by the superoxide-generating oxidase Mox1
24. Redox control of vascular smooth muscle proliferation
25. Stimulation of a vascular smooth muscle cell NAD(P)H oxidase by thrombin: Evidence that p47(phox) may participate in forming this oxidase in vitro and in vivo
26. Platelet-derived growth factor-stimulated superoxide anion production modulates activation of transcription factor NF-kappaB and expression of monocyte chemoattractant protein 1 in human aortic smooth muscle cells
27. Vascular effects following homozygous disruption of p47(phox): An essential component of NADPH oxidase
28. Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice
29. Cell cycle versus density dependence of smooth muscle alpha actin expression in cultured rat aortic smooth muscle cells
30. Downregulation of vascular endothelial growth factor receptors by tumor necrosis factor-alpha in cultured human vascular endothelial cells
31. Induction of vascular endothelial growth factor in balloon-injured baboon arteries: A novel role for reactive oxygen species in atherosclerosis
32. Association of tyrosine-phosphorylated c-Src with the cytoskeleton of hypertrophying myocardium
33. Recombinant 47-kilodalton cytosol factor restores NADPH oxidase in chronic granulomatous disease
34. Aconitase is a sensitive and critical target of oxygen poisoning in cultured mammalian cells and in rat lungs
35. Quantitative assessment of atherosclerotic lesions in mice
36. Enhanced fatty streak formation in C57BL/6J mice by immunization with heat shock protein-65
37. Heat shock protein 90 mediates the balance of nitric oxide and superoxide anion from endothelial nitric-oxide synthase
38. Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis
39. Control of vascular smooth muscle cell growth and its implication in atherosclerosis and restenosis
40. 12-Lipoxygenase products increase monocyte: Endothelial interactions
41. Redox signals that regulate the vascular response to injury
42. Nitric oxide and superoxide inhibit platelet-derived growth factor receptor phosphotyrosine phosphatases
43. Requirement for reactive oxygen species in serum-induced and platelet-derived growth factor-induced growth of airway smooth muscle
44. Vascular gp91(phox): Beyond the endothelium
45. Oxidants and antioxidants in the pathogenesis of atherosclerosis: Implications for the oxidized low density lipoprotein hypothesis
46. Superoxide and peroxynitrite in atherosclerosis