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Volumn 111, Issue , 2017, Pages 110-126

Contribution of the HNE-immunohistochemistry to modern pathological concepts of major human diseases

Author keywords

4 Hydroxy 2 nonenal (HNE); Disease; Immunohistochemistry; Lipid peroxidation; Monoclonal antibodies; Oxidative stress; Pathology; Pathophysiology

Indexed keywords

4 HYDROXYNONENAL; HISTIDINE; 4-HYDROXY-2-NONENAL; ALDEHYDE; AMYLOID BETA PROTEIN; BIOLOGICAL MARKER; MAPT PROTEIN, HUMAN; REACTIVE OXYGEN METABOLITE; TAU PROTEIN; UNSATURATED FATTY ACID;

EID: 85008622650     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2016.12.009     Document Type: Review
Times cited : (69)

References (216)
  • 1
    • 0025814980 scopus 로고
    • Chemistry and biochemistry of 4-hydroxynonenal, malonaldehide and related aldehides
    • Esterbauer, H., Schaur, R.J., Zolner, H., Chemistry and biochemistry of 4-hydroxynonenal, malonaldehide and related aldehides. Free Radic. Biol. Med. 11 (1991), 81–128.
    • (1991) Free Radic. Biol. Med. , vol.11 , pp. 81-128
    • Esterbauer, H.1    Schaur, R.J.2    Zolner, H.3
  • 2
    • 0032568935 scopus 로고    scopus 로고
    • Acrolein is a product of lipid peroxidation. formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins
    • Uchida, K., Kanematsu, Y., Osawa, T., Noguchi, N., Niki, E., Acrolein is a product of lipid peroxidation. formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins. J. Biol. Chem. 273 (1998), 16058–16066.
    • (1998) J. Biol. Chem. , vol.273 , pp. 16058-16066
    • Uchida, K.1    Kanematsu, Y.2    Osawa, T.3    Noguchi, N.4    Niki, E.5
  • 3
    • 0027946778 scopus 로고
    • Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers of atherosclerosis
    • Uchida, K., Toyokuni, S., Nishikawa, K., Kavakishi, S., Oda, H., Hirai, H., Stadtman, E.R., Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers of atherosclerosis. Biochemistry 33 (1994), 12487–12494.
    • (1994) Biochemistry , vol.33 , pp. 12487-12494
    • Uchida, K.1    Toyokuni, S.2    Nishikawa, K.3    Kavakishi, S.4    Oda, H.5    Hirai, H.6    Stadtman, E.R.7
  • 4
    • 0032506040 scopus 로고    scopus 로고
    • Selective inactivation of alpha-ketoglutarat dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal
    • Humphries, K.M., Szweda, L.I., Selective inactivation of alpha-ketoglutarat dehydrogenase: reaction of lipoic acid with 4-hydroxy-2-nonenal. Biochemistry 37 (1998), 15835–15841.
    • (1998) Biochemistry , vol.37 , pp. 15835-15841
    • Humphries, K.M.1    Szweda, L.I.2
  • 5
    • 0037172778 scopus 로고    scopus 로고
    • Identification of bovine hart cytocrome c oxidase subunit modified by the lipid peroxidation product 4-hydroxy-2-nonenal
    • Musatov, A., Carrol, C.A., Liu, Y., Henderson, G.I., Weintraub, S.T., Robinson, N.C., Identification of bovine hart cytocrome c oxidase subunit modified by the lipid peroxidation product 4-hydroxy-2-nonenal. Biochemistry 41 (2002), 8212–8220.
    • (2002) Biochemistry , vol.41 , pp. 8212-8220
    • Musatov, A.1    Carrol, C.A.2    Liu, Y.3    Henderson, G.I.4    Weintraub, S.T.5    Robinson, N.C.6
  • 6
    • 0041669506 scopus 로고    scopus 로고
    • Oxidized LDL and 4-hydroxynonenal modulate tyrosin kinase receptor activity
    • Negre-Salvayre, A., Viera, O., Escargueil- Blanc, I., Salvayre, R., Oxidized LDL and 4-hydroxynonenal modulate tyrosin kinase receptor activity. Mol. Asp. Med. 24 (2003), 251–261.
    • (2003) Mol. Asp. Med. , vol.24 , pp. 251-261
    • Negre-Salvayre, A.1    Viera, O.2    Escargueil-Blanc, I.3    Salvayre, R.4
  • 7
    • 0037411282 scopus 로고    scopus 로고
    • 4-hydroxy-2-nonenal a product and mediator of oxidative stress
    • Uchida, K., 4-hydroxy-2-nonenal a product and mediator of oxidative stress. Prog. Lipid Res. 42 (2003), 318–343.
    • (2003) Prog. Lipid Res. , vol.42 , pp. 318-343
    • Uchida, K.1
  • 9
    • 77956567906 scopus 로고    scopus 로고
    • Advances in methods for the determination of biologically relevant lipid peroxidation products
    • Spickett, C.M., Wiswedel, I., Werner, S., Zarkovic, K., Zarkovic, N., Advances in methods for the determination of biologically relevant lipid peroxidation products. Free Radic. Res. 44 (2010), 1172–1202.
    • (2010) Free Radic. Res. , vol.44 , pp. 1172-1202
    • Spickett, C.M.1    Wiswedel, I.2    Werner, S.3    Zarkovic, K.4    Zarkovic, N.5
  • 12
    • 0026446896 scopus 로고
    • Studies on epitopes on low-density lipoprotein modified by 4-hydroxynonenal. biochemical characterization and determination
    • Chen, Q., Esterbauer, H., Jurgens, G., Studies on epitopes on low-density lipoprotein modified by 4-hydroxynonenal. biochemical characterization and determination. Biochem. J. 288 (1992), 249–254.
    • (1992) Biochem. J. , vol.288 , pp. 249-254
    • Chen, Q.1    Esterbauer, H.2    Jurgens, G.3
  • 13
    • 0027946778 scopus 로고
    • Michael addition-type 4hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers for atherosclerosis
    • Uchida, K., Toyokuni, S., Nishikawa, K., Kawakishi, S., Oda, H., Hiai, H., Stadtmen, E.R., Michael addition-type 4hydroxy-2-nonenal adducts in modified low-density lipoproteins: markers for atherosclerosis. Biochemistry 33 (1994), 12487–12494.
    • (1994) Biochemistry , vol.33 , pp. 12487-12494
    • Uchida, K.1    Toyokuni, S.2    Nishikawa, K.3    Kawakishi, S.4    Oda, H.5    Hiai, H.6    Stadtmen, E.R.7
  • 17
    • 0029906188 scopus 로고    scopus 로고
    • Monoclonal antibodies for detection of 4-hydroxynonenal modified proteins
    • Waeg, G., Dimsity, G., Esterbauer, H., Monoclonal antibodies for detection of 4-hydroxynonenal modified proteins. Free. Radic. Res. 25 (1996), 149–159.
    • (1996) Free. Radic. Res. , vol.25 , pp. 149-159
    • Waeg, G.1    Dimsity, G.2    Esterbauer, H.3
  • 19
    • 33749244131 scopus 로고    scopus 로고
    • Enzyme-linked immunosorbent assay for 4-hydroxynonenal-histidine conjugates
    • Borovic, S., Rabuzin, F., Waeg, G., Zarkovic, N., Enzyme-linked immunosorbent assay for 4-hydroxynonenal-histidine conjugates. Free Radic. Res. 40 (2006), 809–820.
    • (2006) Free Radic. Res. , vol.40 , pp. 809-820
    • Borovic, S.1    Rabuzin, F.2    Waeg, G.3    Zarkovic, N.4
  • 20
    • 84878824682 scopus 로고    scopus 로고
    • Measurement of HNE protein adducts in human plasma and serum by ELISA - Comparison of two primary antibodies
    • Weber, D., Milkovic, L., Bennett, S.J., Griffiths, H.R., Zarkovic, N., Grune, T., Measurement of HNE protein adducts in human plasma and serum by ELISA - Comparison of two primary antibodies. Redox Biol. 1 (2013), 223–226.
    • (2013) Redox Biol. , vol.1 , pp. 223-226
    • Weber, D.1    Milkovic, L.2    Bennett, S.J.3    Griffiths, H.R.4    Zarkovic, N.5    Grune, T.6
  • 22
    • 0029862568 scopus 로고    scopus 로고
    • Immunochemical evidence supporting 2-pentylpyrrole formation on proteins exposed to 4-hydroxy-2-nonenal
    • Sayre, L.M., Sha, W., Xu, G., Kaur, K., Nadkarni, D., Subbanagounder, G., Salomon, R.G., Immunochemical evidence supporting 2-pentylpyrrole formation on proteins exposed to 4-hydroxy-2-nonenal. Chem. Res. Toxicol. 9 (1996), 1194–1201.
    • (1996) Chem. Res. Toxicol. , vol.9 , pp. 1194-1201
    • Sayre, L.M.1    Sha, W.2    Xu, G.3    Kaur, K.4    Nadkarni, D.5    Subbanagounder, G.6    Salomon, R.G.7
  • 23
    • 0032493431 scopus 로고    scopus 로고
    • Structural characterization and immunochemical detection of fluorophore derived from 4-hydroxy-2-nonenal and lysine
    • Tsai, L., Szweda, P.A., Vinogradova, O., Szweda, L.I., Structural characterization and immunochemical detection of fluorophore derived from 4-hydroxy-2-nonenal and lysine. Proc. Natl. Acad. Sci. USA 95 (1998), 7975–7980.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 7975-7980
    • Tsai, L.1    Szweda, P.A.2    Vinogradova, O.3    Szweda, L.I.4
  • 24
    • 0034640337 scopus 로고    scopus 로고
    • Detection of lipofuscin-like fluorophore in oxidized human low-density lipoprotein. 4-Hydroxy-2-nonenal as a potential source of fluorescent chromophore
    • Itakura, K., Oya-Ito, T., Osawa, T., Yamada, S., Toyokuni, S., Shibata, N., Kobayashi, M., Uchida, K., Detection of lipofuscin-like fluorophore in oxidized human low-density lipoprotein. 4-Hydroxy-2-nonenal as a potential source of fluorescent chromophore. FEBS Lett. 473 (2000), 249–253.
    • (2000) FEBS Lett. , vol.473 , pp. 249-253
    • Itakura, K.1    Oya-Ito, T.2    Osawa, T.3    Yamada, S.4    Toyokuni, S.5    Shibata, N.6    Kobayashi, M.7    Uchida, K.8
  • 25
    • 0019822988 scopus 로고
    • Tresholds in cerebral ishemia- the ishemic penumbra
    • (725)
    • Astrup, J., Siesjo, B.K., Symon, L., Tresholds in cerebral ishemia- the ishemic penumbra. Stroke, 12, 1981, 725 (725).
    • (1981) Stroke , vol.12 , pp. 725
    • Astrup, J.1    Siesjo, B.K.2    Symon, L.3
  • 26
    • 0033199996 scopus 로고    scopus 로고
    • Pathobiology of ischaemic shock: an integrated view
    • Dirnagl, I., Iadocola, C., Moskowitz, M.A., Pathobiology of ischaemic shock: an integrated view. Trends Neurosci. 22 (1999), 391–397.
    • (1999) Trends Neurosci. , vol.22 , pp. 391-397
    • Dirnagl, I.1    Iadocola, C.2    Moskowitz, M.A.3
  • 27
    • 0029888311 scopus 로고    scopus 로고
    • Role of oxidants in ischemic brain damage
    • Chan, P.H., Role of oxidants in ischemic brain damage. Stroke 27 (1996), 1124–1129.
    • (1996) Stroke , vol.27 , pp. 1124-1129
    • Chan, P.H.1
  • 28
    • 78651102543 scopus 로고    scopus 로고
    • Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis
    • Hoffman, W.H., Siedalak, S.L., Wang, Y., Castellani, R.J., Smith, M.A., Oxidative damage is present in the fatal brain edema of diabetic ketoacidosis. Brain Res. 1369 (2010), 194–202.
    • (2010) Brain Res. , vol.1369 , pp. 194-202
    • Hoffman, W.H.1    Siedalak, S.L.2    Wang, Y.3    Castellani, R.J.4    Smith, M.A.5
  • 29
    • 3042545191 scopus 로고    scopus 로고
    • Canabinoids as neuroprotective agents in traumatic brain injury
    • Biegon, A., Canabinoids as neuroprotective agents in traumatic brain injury. Curr. Pharm. Des. 10 (2004), 2177–2183.
    • (2004) Curr. Pharm. Des. , vol.10 , pp. 2177-2183
    • Biegon, A.1
  • 30
    • 46649098179 scopus 로고    scopus 로고
    • Oxidative stress and modification of synaptic proteins in hippocampus after traumatic injury
    • Ansari, M.A., Roberts, K.N., Scheff, S.W., Oxidative stress and modification of synaptic proteins in hippocampus after traumatic injury. Free Radic. Biol. Med. 43 (2008), 443–452.
    • (2008) Free Radic. Biol. Med. , vol.43 , pp. 443-452
    • Ansari, M.A.1    Roberts, K.N.2    Scheff, S.W.3
  • 31
    • 0003040647 scopus 로고
    • Central nervous system trauma status report
    • J. Povlishhok D. Backer National Institutes of Health Washington DC
    • Cooper, P., Central nervous system trauma status report. Povlishhok, J., Backer, D., (eds.) Delayed brain injury, 1985, National Institutes of Health, Washington DC, 217–282.
    • (1985) Delayed brain injury , pp. 217-282
    • Cooper, P.1
  • 32
    • 0030920387 scopus 로고    scopus 로고
    • 4-hydroxynonenal, a lipid peroxidation product, rapidli accumulates following traumatic spinal cord injury and inhibits glutamat uptake
    • Springer, J.E., Azbil, R.D., Mark, R.J., Begley, J.G., Waeg, G., Mattson, M.P., 4-hydroxynonenal, a lipid peroxidation product, rapidli accumulates following traumatic spinal cord injury and inhibits glutamat uptake. J. Neurochem. 68 (1997), 2469–2476.
    • (1997) J. Neurochem. , vol.68 , pp. 2469-2476
    • Springer, J.E.1    Azbil, R.D.2    Mark, R.J.3    Begley, J.G.4    Waeg, G.5    Mattson, M.P.6
  • 33
    • 21144451431 scopus 로고    scopus 로고
    • Accumulation of acrolein-protein adducts after traumatic spinal injury
    • Luo, J., Uchida, K., Shi, R., Accumulation of acrolein-protein adducts after traumatic spinal injury. Neurochem. Res. 30 (2005), 291–295.
    • (2005) Neurochem. Res. , vol.30 , pp. 291-295
    • Luo, J.1    Uchida, K.2    Shi, R.3
  • 34
    • 0030746621 scopus 로고    scopus 로고
    • The lipid peroxidation product 4-hydroxy-2-trans- nonenal, alters the conformation of cortical synaptosomal membrane proteins
    • Subramaniam, R., Roediger, F., Jordan, B., Mattson, M.P., Kellaer, J.N., Waeg, G., Buterfield, D.A., The lipid peroxidation product 4-hydroxy-2-trans- nonenal, alters the conformation of cortical synaptosomal membrane proteins. J. Neurochem. 69 (1997), 1161–1169.
    • (1997) J. Neurochem. , vol.69 , pp. 1161-1169
    • Subramaniam, R.1    Roediger, F.2    Jordan, B.3    Mattson, M.P.4    Kellaer, J.N.5    Waeg, G.6    Buterfield, D.A.7
  • 36
    • 46849122006 scopus 로고    scopus 로고
    • Mitochondrial defect in acute multiple sclerosis lesion
    • Mahad, D., Ziabreva, I., Lassman, H., Turnbull, D., Mitochondrial defect in acute multiple sclerosis lesion. Brain 131 (2008), 1722–1735.
    • (2008) Brain , vol.131 , pp. 1722-1735
    • Mahad, D.1    Ziabreva, I.2    Lassman, H.3    Turnbull, D.4
  • 37
    • 35649018602 scopus 로고    scopus 로고
    • Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?
    • Marik, C., Felts, P., Bauer, J., Lassman, H., Smith, K.J., Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?. Brain 130 (2007), 2800–2815.
    • (2007) Brain , vol.130 , pp. 2800-2815
    • Marik, C.1    Felts, P.2    Bauer, J.3    Lassman, H.4    Smith, K.J.5
  • 38
    • 73549089256 scopus 로고    scopus 로고
    • Multiple sclerosis: distribution of inflammatory cells in newly forming lesions
    • Henderson, A.P.D., Barnet, M.H., Parratt, J.D.E., Prineas, J.W., Multiple sclerosis: distribution of inflammatory cells in newly forming lesions. Ann. Neurol., 66(739), 2009, 753.
    • (2009) Ann. Neurol. , vol.66 , Issue.739 , pp. 753
    • Henderson, A.P.D.1    Barnet, M.H.2    Parratt, J.D.E.3    Prineas, J.W.4
  • 41
    • 0034725724 scopus 로고    scopus 로고
    • Phagocites and oxidative stress
    • Babior, M.B., Phagocites and oxidative stress. Am. J. Med. 109 (2000), 33–44.
    • (2000) Am. J. Med. , vol.109 , pp. 33-44
    • Babior, M.B.1
  • 42
    • 77949593677 scopus 로고    scopus 로고
    • Targeting and regulation of reactive oxigen species by Nox family NADPH oxidases
    • Leto, T.L., Morand, S., Hurt, D., Uveyema, T., Targeting and regulation of reactive oxigen species by Nox family NADPH oxidases. Antioxid. Redox Signal. 11 (2009), 2607–2619.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 2607-2619
    • Leto, T.L.1    Morand, S.2    Hurt, D.3    Uveyema, T.4
  • 47
    • 0035003439 scopus 로고    scopus 로고
    • Chemistry and biochemistry of oxidative stress in neurodegenerative disease
    • Sayr, L.M., Smith, M.A., Perry, G., Chemistry and biochemistry of oxidative stress in neurodegenerative disease. Curr. Med. Chem. 8 (2001), 721–738.
    • (2001) Curr. Med. Chem. , vol.8 , pp. 721-738
    • Sayr, L.M.1    Smith, M.A.2    Perry, G.3
  • 48
    • 52149102270 scopus 로고    scopus 로고
    • Age related alteration of oxidative stress in the mouse hippocampal CA1 sector
    • Huyakava, N., Yokoyama, H., Kato, H., Araki, T., Age related alteration of oxidative stress in the mouse hippocampal CA1 sector. Exp. Mol. Path. 85 (2008), 135–140.
    • (2008) Exp. Mol. Path. , vol.85 , pp. 135-140
    • Huyakava, N.1    Yokoyama, H.2    Kato, H.3    Araki, T.4
  • 50
    • 0035093896 scopus 로고    scopus 로고
    • Immunohistochemical investigation of the brain of aged dogs- I. detection of neurofibrillary tangles and of 4-hydroxinonenal protein, an oxidative damage product, in senile plaques
    • Papaioannou, N., Tooten, P.C.J., van Ederen, A.M., Bohl, J.R.E., Rofina, J., Tsangaris, T., Gruys, E., Immunohistochemical investigation of the brain of aged dogs- I. detection of neurofibrillary tangles and of 4-hydroxinonenal protein, an oxidative damage product, in senile plaques. Amyloid. J. Protein Fold Disord. 8 (2001), 11–21.
    • (2001) Amyloid. J. Protein Fold Disord. , vol.8 , pp. 11-21
    • Papaioannou, N.1    Tooten, P.C.J.2    van Ederen, A.M.3    Bohl, J.R.E.4    Rofina, J.5    Tsangaris, T.6    Gruys, E.7
  • 52
    • 0031720801 scopus 로고    scopus 로고
    • The incidence of dementia: a meta-analysis
    • Jorm, A.F., Jolley, D., The incidence of dementia: a meta-analysis. Neurology 51 (1998), 728–733.
    • (1998) Neurology , vol.51 , pp. 728-733
    • Jorm, A.F.1    Jolley, D.2
  • 53
    • 0029091572 scopus 로고
    • Amyloid beta amyloidosis in Alzheimer's disease
    • Price, D.L., Sisodia, S.S., Gandy, S.E., Amyloid beta amyloidosis in Alzheimer's disease. Curr. Opin. Neurol. 8 (1995), 268–274.
    • (1995) Curr. Opin. Neurol. , vol.8 , pp. 268-274
    • Price, D.L.1    Sisodia, S.S.2    Gandy, S.E.3
  • 54
    • 0033712579 scopus 로고
    • 4-hydroxinonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease
    • Shringarpure, R., Grune, T., Sitte, N., Davies, K.J., 4-hydroxinonenal-modified amyloid-beta peptide inhibits the proteasome: possible importance in Alzheimer's disease. Cell. Mol. Life Sci. 57 (1995), 1802–1809.
    • (1995) Cell. Mol. Life Sci. , vol.57 , pp. 1802-1809
    • Shringarpure, R.1    Grune, T.2    Sitte, N.3    Davies, K.J.4
  • 55
    • 0030963753 scopus 로고    scopus 로고
    • The isoprostanes. unique bioactive products of lipid peroxidation
    • Morrow, J.D., Roberts, L.J., The isoprostanes. unique bioactive products of lipid peroxidation. Prog. Lipid Res. 36 (1997), 1–21.
    • (1997) Prog. Lipid Res. , vol.36 , pp. 1-21
    • Morrow, J.D.1    Roberts, L.J.2
  • 56
    • 0029073455 scopus 로고
    • Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease
    • Lovell, M.A., Ehmann, W.D., Butler, S.M., Markesbery, W.R., Elevated thiobarbituric acid-reactive substances and antioxidant enzyme activity in the brain in Alzheimer's disease. Neurology 45 (1995), 1594–1601.
    • (1995) Neurology , vol.45 , pp. 1594-1601
    • Lovell, M.A.1    Ehmann, W.D.2    Butler, S.M.3    Markesbery, W.R.4
  • 57
    • 0030966546 scopus 로고    scopus 로고
    • Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid β-peptide: role of the lipid peroxidation product 4-hydroxynonenal
    • Keller, J.N., Pang, Z., Geddes, J.W., Begley, J.G., Germeyer, A., Waeg, G., Mattson, M.P., Impairment of glucose and glutamate transport and induction of mitochondrial oxidative stress and dysfunction in synaptosomes by amyloid β-peptide: role of the lipid peroxidation product 4-hydroxynonenal. J. Neurochem. 69 (1997), 273–284.
    • (1997) J. Neurochem. , vol.69 , pp. 273-284
    • Keller, J.N.1    Pang, Z.2    Geddes, J.W.3    Begley, J.G.4    Germeyer, A.5    Waeg, G.6    Mattson, M.P.7
  • 59
    • 0030986669 scopus 로고    scopus 로고
    • Evidence that 4-hydroxynonenyl mediates oxidative stress- induced neuronal apoptosis
    • Kruman, I., Bruce-Keler, A.J., Bredesen, D., Waeg, G., Mattson, M.P., Evidence that 4-hydroxynonenyl mediates oxidative stress- induced neuronal apoptosis. J. Neurosci. 17 (1997), 5089–5100.
    • (1997) J. Neurosci. , vol.17 , pp. 5089-5100
    • Kruman, I.1    Bruce-Keler, A.J.2    Bredesen, D.3    Waeg, G.4    Mattson, M.P.5
  • 60
    • 0031980065 scopus 로고    scopus 로고
    • Four-hydroxynonenal a product of lipid peroxidation, is increased in the brain in Alzheimer's disease
    • Markesbery, W.R., Lovell, M.A., Four-hydroxynonenal a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiol. Aging 19 (1998), 33–36.
    • (1998) Neurobiol. Aging , vol.19 , pp. 33-36
    • Markesbery, W.R.1    Lovell, M.A.2
  • 61
    • 77952672909 scopus 로고    scopus 로고
    • Increased levels of 4-hydroxinonenal and acrolein in the brain preclinical Alzheimer disease
    • Bradley, M.A., Markesbey, W.R., Lovell, M.A., Increased levels of 4-hydroxinonenal and acrolein in the brain preclinical Alzheimer disease. Free Radic. Biol. Med. 48 (2010), 1570–1576.
    • (2010) Free Radic. Biol. Med. , vol.48 , pp. 1570-1576
    • Bradley, M.A.1    Markesbey, W.R.2    Lovell, M.A.3
  • 64
    • 0030040310 scopus 로고    scopus 로고
    • 4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures
    • Montine, T.J., Amarnath, V., Martin, M.E., Strittmatter, W.J., Graham, D.G., 4-hydroxy-2-nonenal is cytotoxic and cross-links cytoskeletal proteins in P19 neuroglial cultures. Am. J. Pathol. 148 (1996), 89–93.
    • (1996) Am. J. Pathol. , vol.148 , pp. 89-93
    • Montine, T.J.1    Amarnath, V.2    Martin, M.E.3    Strittmatter, W.J.4    Graham, D.G.5
  • 66
    • 0023445343 scopus 로고
    • Stricture-activity relationship of 4-hidroxyalkenals in the conjugation catalysed by mammalian glutathione transferases
    • Danielson, U.H., Esterbauer, H., Mannervik, B., Stricture-activity relationship of 4-hidroxyalkenals in the conjugation catalysed by mammalian glutathione transferases. Biochem. J. 247 (1987), 707–713.
    • (1987) Biochem. J. , vol.247 , pp. 707-713
    • Danielson, U.H.1    Esterbauer, H.2    Mannervik, B.3
  • 67
    • 0031678044 scopus 로고    scopus 로고
    • Decrease glutathion transferase in brain and ventricular fluid in Alzheimer's disease
    • Lovell, M.A., Markesbery, W.R., Decrease glutathion transferase in brain and ventricular fluid in Alzheimer's disease. Neurology 51 (1998), 1561–1566.
    • (1998) Neurology , vol.51 , pp. 1561-1566
    • Lovell, M.A.1    Markesbery, W.R.2
  • 68
    • 0028690470 scopus 로고
    • DNA adducts of α, β-unsaturated aldehydes and dicarbonyl compounds
    • Marnett, L.J., DNA adducts of α, β-unsaturated aldehydes and dicarbonyl compounds. IARC Sci. Publ. 125 (1994), 151–163.
    • (1994) IARC Sci. Publ. , vol.125 , pp. 151-163
    • Marnett, L.J.1
  • 69
    • 0035112495 scopus 로고    scopus 로고
    • Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal culture
    • Lovell, M.A., Xie, C., Markesbery, W.R., Acrolein is increased in Alzheimer's disease brain and is toxic to primary hippocampal culture. Neurobio. Aging 22 (2001), 187–194.
    • (2001) Neurobio. Aging , vol.22 , pp. 187-194
    • Lovell, M.A.1    Xie, C.2    Markesbery, W.R.3
  • 70
    • 0023881464 scopus 로고
    • Activation of the microsomal glutathion-S transferase and reduction of the glutathion dependent protection against lipid peroxidation by acrolein
    • Haenen, G.R., Vermeulen, N.P., Tai Tin Tsoi, J.N., Ragetli, H., Timmerman, H., Blast, A., Activation of the microsomal glutathion-S transferase and reduction of the glutathion dependent protection against lipid peroxidation by acrolein. Biochem. Pharmacol. 37 (1988), 1933–1938.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 1933-1938
    • Haenen, G.R.1    Vermeulen, N.P.2    Tai Tin Tsoi, J.N.3    Ragetli, H.4    Timmerman, H.5    Blast, A.6
  • 71
    • 0032568935 scopus 로고    scopus 로고
    • Acrolein is a product of lipid peroxidation, formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins
    • Uchida, K., Kanematsu, Y., Osawa, T., Noguchi, N., Niki, E., Acrolein is a product of lipid peroxidation, formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins. J. Biol. Chem. 273 (1998), 16058–16066.
    • (1998) J. Biol. Chem. , vol.273 , pp. 16058-16066
    • Uchida, K.1    Kanematsu, Y.2    Osawa, T.3    Noguchi, N.4    Niki, E.5
  • 72
    • 0032905632 scopus 로고    scopus 로고
    • Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease
    • Calingasan, N.Y., Uchida, K., Gibson, G.E., Protein-bound acrolein: a novel marker of oxidative stress in Alzheimer's disease. J. Neurochem. 72 (1999), 751–756.
    • (1999) J. Neurochem. , vol.72 , pp. 751-756
    • Calingasan, N.Y.1    Uchida, K.2    Gibson, G.E.3
  • 76
    • 0029927679 scopus 로고    scopus 로고
    • Intense superoxide dismutas-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement
    • Shibata, N., Hirano, A., Kobayashi, M., Siddique, T., Deng, H.X., Hing, W.Y., Kato, T., Asayama, K., Intense superoxide dismutas-1 immunoreactivity in intracytoplasmic hyaline inclusions of familial amyotrophic lateral sclerosis with posterior column involvement. J. Neuropath. Exp. Neurol. 55 (1996), 481–490.
    • (1996) J. Neuropath. Exp. Neurol. , vol.55 , pp. 481-490
    • Shibata, N.1    Hirano, A.2    Kobayashi, M.3    Siddique, T.4    Deng, H.X.5    Hing, W.Y.6    Kato, T.7    Asayama, K.8
  • 77
    • 0033004618 scopus 로고    scopus 로고
    • The lipid peroxidation product 4-hydroxynonenal impairs glutamat and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells
    • Pedersen, W.A., Cashman, N.R., Mattson, M.P., The lipid peroxidation product 4-hydroxynonenal impairs glutamat and glucose transport and choline acetyltransferase activity in NSC-19 motor neuron cells. Exp. Neurol. 155 (1999), 1–10.
    • (1999) Exp. Neurol. , vol.155 , pp. 1-10
    • Pedersen, W.A.1    Cashman, N.R.2    Mattson, M.P.3
  • 78
    • 0031768026 scopus 로고    scopus 로고
    • Protein modification by the lipid peroxidation product 4-hydroxynonenal I the spinal cord of amyotrophic lateral sclerosis patients
    • Pedersen, W.A., Fu, W., Keller, J.N., Markesbery, W.R., Appel, Smith, R.G., Kasarkis, E., Mattson, M.P., Protein modification by the lipid peroxidation product 4-hydroxynonenal I the spinal cord of amyotrophic lateral sclerosis patients. Ann. Neurol. 44 (1998), 819–824.
    • (1998) Ann. Neurol. , vol.44 , pp. 819-824
    • Pedersen, W.A.1    Fu, W.2    Keller, J.N.3    Markesbery, W.R.4    Appel5    Smith, R.G.6    Kasarkis, E.7    Mattson, M.P.8
  • 81
    • 0037025111 scopus 로고    scopus 로고
    • Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Perkinsons disease
    • Mc Naught, K.S., Belizaire, R., Jenner, P., Olanov, C.W., Isacson, O., Selective loss of 20S proteasome alpha-subunits in the substantia nigra pars compacta in Perkinsons disease. Neurosci. Lett. 326 (2002), 155–158.
    • (2002) Neurosci. Lett. , vol.326 , pp. 155-158
    • Mc Naught, K.S.1    Belizaire, R.2    Jenner, P.3    Olanov, C.W.4    Isacson, O.5
  • 82
    • 0025963530 scopus 로고
    • Selective increase of iron in substantia nigra zona compacta of parkinsonian brains
    • Sofic, E., Paulus, W., Jellinge, K., Riederer, P., Youdim, M.B., Selective increase of iron in substantia nigra zona compacta of parkinsonian brains. J. Neurochem. 56 (1991), 978–982.
    • (1991) J. Neurochem. , vol.56 , pp. 978-982
    • Sofic, E.1    Paulus, W.2    Jellinge, K.3    Riederer, P.4    Youdim, M.B.5
  • 84
    • 0035937522 scopus 로고    scopus 로고
    • Dopamine induced protein damage in mitochondrial-synaptosomal fraction of rat brain
    • Khan, F.H., Saha, M., Chakrabarti, S., Dopamine induced protein damage in mitochondrial-synaptosomal fraction of rat brain. Brain Res. 895 (2001), 245–249.
    • (2001) Brain Res. , vol.895 , pp. 245-249
    • Khan, F.H.1    Saha, M.2    Chakrabarti, S.3
  • 85
    • 0032911488 scopus 로고    scopus 로고
    • Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
    • Zhang, J., Perry, G., Smith, M.A., Robertson, D., Olson, S.J., Graham, D.G., Montine, T.J., Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am. J. Pathol. 154 (1999), 1423–1429.
    • (1999) Am. J. Pathol. , vol.154 , pp. 1423-1429
    • Zhang, J.1    Perry, G.2    Smith, M.A.3    Robertson, D.4    Olson, S.J.5    Graham, D.G.6    Montine, T.J.7
  • 86
    • 0030878073 scopus 로고    scopus 로고
    • Oxidative DNA damage in the parkinsonian brain: apparent selective increase in 8-hydroxyguanine level in substantia nigra
    • Alam, Z., Jenner, A., Daniel, S.E., Lees, A.J., Cairns, N., Marsden, D.C., Jenner, P., Halliwell, B., Oxidative DNA damage in the parkinsonian brain: apparent selective increase in 8-hydroxyguanine level in substantia nigra. J. Neurochem. 69 (1997), 1196–1203.
    • (1997) J. Neurochem. , vol.69 , pp. 1196-1203
    • Alam, Z.1    Jenner, A.2    Daniel, S.E.3    Lees, A.J.4    Cairns, N.5    Marsden, D.C.6    Jenner, P.7    Halliwell, B.8
  • 90
    • 0027485889 scopus 로고
    • Stimulation of HeLa cell growth by physiological concentrations of 4-hydroxynonenal
    • Zarkovic, N., Ilic, Z., Jurin, M., Scahur, R.J., Puhl, H., Esterbauer, H., Stimulation of HeLa cell growth by physiological concentrations of 4-hydroxynonenal. Cell Biochem. Funct. 11 (1993), 279–286.
    • (1993) Cell Biochem. Funct. , vol.11 , pp. 279-286
    • Zarkovic, N.1    Ilic, Z.2    Jurin, M.3    Scahur, R.J.4    Puhl, H.5    Esterbauer, H.6
  • 91
    • 0043172469 scopus 로고    scopus 로고
    • 4-Hydroxynonenal as a bioactive marker of pathophysiological processes
    • Zarkovic, N., 4-Hydroxynonenal as a bioactive marker of pathophysiological processes. Mol. Asp. Med. 24 (2003), 281–291.
    • (2003) Mol. Asp. Med. , vol.24 , pp. 281-291
    • Zarkovic, N.1
  • 93
    • 77955921659 scopus 로고    scopus 로고
    • A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain –derived neurotrophic factor
    • Park, H.R., Park, M., Choi, J., Park, K.J., Chung, H.Y., Lee, J., A high-fat diet impairs neurogenesis: involvement of lipid peroxidation and brain –derived neurotrophic factor. Neurosci. Lett. 482 (2010), 235–239.
    • (2010) Neurosci. Lett. , vol.482 , pp. 235-239
    • Park, H.R.1    Park, M.2    Choi, J.3    Park, K.J.4    Chung, H.Y.5    Lee, J.6
  • 94
    • 28644433164 scopus 로고    scopus 로고
    • Immunohistochemical appearance of HNE-protein conjugates in human astrocytomas
    • Zarkovic, K., Juric, G., Waeg, G., Kolenc, D., Zarkovic, N., Immunohistochemical appearance of HNE-protein conjugates in human astrocytomas. BioFactors 24 (2005), 33–40.
    • (2005) BioFactors , vol.24 , pp. 33-40
    • Zarkovic, K.1    Juric, G.2    Waeg, G.3    Kolenc, D.4    Zarkovic, N.5
  • 95
    • 76349092912 scopus 로고    scopus 로고
    • Distribution of 4-hydroxynonenal-proteinconjugates as a marker of lipid peroxidation and parameter of malignancy in astrocyticand ependymal tumors of the brain
    • GJS Juric-Sekhar, G., Zarkovic, K., Waeg, G., Cipak, A., Žarkovic, N., Distribution of 4-hydroxynonenal-proteinconjugates as a marker of lipid peroxidation and parameter of malignancy in astrocyticand ependymal tumors of the brain. Tumori 95 (2009), 762–768.
    • (2009) Tumori , vol.95 , pp. 762-768
    • GJS Juric-Sekhar, G.1    Zarkovic, K.2    Waeg, G.3    Cipak, A.4    Žarkovic, N.5
  • 96
    • 80051605012 scopus 로고    scopus 로고
    • The co-expression of 4-hydroxynonenal and prominin-1 in glioblastomas
    • Kolenc, D., Jakovcevic, A., Macan, M., Zarkovic, K., The co-expression of 4-hydroxynonenal and prominin-1 in glioblastomas. Transl. Neurosci. 2 (2011), 163–167.
    • (2011) Transl. Neurosci. , vol.2 , pp. 163-167
    • Kolenc, D.1    Jakovcevic, A.2    Macan, M.3    Zarkovic, K.4
  • 98
    • 84923930957 scopus 로고    scopus 로고
    • Revealing mechanisms of selective, concentration-dependent potentials of 4-hydroxy-2-nonenal to induce apoptosis in cancer cells through inactivation of membrane-associated catalase
    • Bauer, G., Zarkovic, N., Revealing mechanisms of selective, concentration-dependent potentials of 4-hydroxy-2-nonenal to induce apoptosis in cancer cells through inactivation of membrane-associated catalase. Free Radic. Biol. Med. 81 (2015), 128–144.
    • (2015) Free Radic. Biol. Med. , vol.81 , pp. 128-144
    • Bauer, G.1    Zarkovic, N.2
  • 99
    • 0030799043 scopus 로고    scopus 로고
    • Low density lipoprotein oxidation and its pathobiological significance
    • Steinberg, D., Low density lipoprotein oxidation and its pathobiological significance. J. Biol. Chem. 272 (1997), 20963–20966.
    • (1997) J. Biol. Chem. , vol.272 , pp. 20963-20966
    • Steinberg, D.1
  • 100
    • 0030729868 scopus 로고    scopus 로고
    • Mechanism of oxidative damage of low-density lipoproteine in human atherosclerosis
    • Heinecke, J.W., Mechanism of oxidative damage of low-density lipoproteine in human atherosclerosis. Curr. Opin. Lipidol. 8 (1997), 268–274.
    • (1997) Curr. Opin. Lipidol. , vol.8 , pp. 268-274
    • Heinecke, J.W.1
  • 101
    • 18644384153 scopus 로고    scopus 로고
    • pro-inflammatory properties of immune complex prepared with purified human oxLDL antibodies and human oxJDL. Clin. Immunolo.105:81-92; 1002.
    • G. Virella, D.H. Atchely, S. Koskinen, D. Zheng, M. Lopes-VirellaPro-atherogenic and pro-inflammatory properties of immune complex prepared with purified human oxLDL antibodies and human oxJDL. Clin. Immunolo.105:81-92; 1002.
    • Virella, G.1    Atchely, D.H.2    Koskinen, S.3    Zheng, D.4    Lopes-VirellaPro-atherogenic, M.5
  • 102
    • 0033521695 scopus 로고
    • Receptors for oxidized low density lipoprotein
    • Steinbrecher, U.P., Receptors for oxidized low density lipoprotein. Biochem. Biophys. Acta 1436 (1990), 279–298.
    • (1990) Biochem. Biophys. Acta , vol.1436 , pp. 279-298
    • Steinbrecher, U.P.1
  • 103
    • 17444368974 scopus 로고    scopus 로고
    • Glycation of low-density lipoproteins by methilglyoxal and flycolaldehyde gives rise to the in vitro formation of lipid-laden cells
    • Brown, B.E., Dean, R.T., Davies, M.J., Glycation of low-density lipoproteins by methilglyoxal and flycolaldehyde gives rise to the in vitro formation of lipid-laden cells. Diabetologia 48 (2005), 361–369.
    • (2005) Diabetologia , vol.48 , pp. 361-369
    • Brown, B.E.1    Dean, R.T.2    Davies, M.J.3
  • 104
    • 0027519515 scopus 로고
    • Imunostaining oh human autopy aortas with antibodies to modifier apolipoprotein B and apoprotein(a)
    • Jurgens, G., Esterbauer, H., Mair, S., Ledinski, G., Dinges, H.P., Imunostaining oh human autopy aortas with antibodies to modifier apolipoprotein B and apoprotein(a). Atheroscler. Thromb. 13:11 (1993), 1589–1699.
    • (1993) Atheroscler. Thromb. , vol.13 , Issue.11 , pp. 1589-1699
    • Jurgens, G.1    Esterbauer, H.2    Mair, S.3    Ledinski, G.4    Dinges, H.P.5
  • 105
    • 0029165212 scopus 로고
    • Inhibition of adenine nucleotide translocator by lipid peroxidation products
    • Chen, J.J., Bertrand, H., Yu, B.P., Inhibition of adenine nucleotide translocator by lipid peroxidation products. Free. Radic. Biol. Med. 19 (1995), 583–590.
    • (1995) Free. Radic. Biol. Med. , vol.19 , pp. 583-590
    • Chen, J.J.1    Bertrand, H.2    Yu, B.P.3
  • 107
    • 33748752424 scopus 로고    scopus 로고
    • Identification of autoantibodies in human plasma recognized an apoB-100 LDL receptor binding site peptide
    • Fredrikson, G.N., Berglund, G., Alm, R., Nilsson, J.A., Shah, P.K., Nilsson, J., Identification of autoantibodies in human plasma recognized an apoB-100 LDL receptor binding site peptide. J. Lipid Res. 47 (2006), 2049–2054.
    • (2006) J. Lipid Res. , vol.47 , pp. 2049-2054
    • Fredrikson, G.N.1    Berglund, G.2    Alm, R.3    Nilsson, J.A.4    Shah, P.K.5    Nilsson, J.6
  • 108
    • 33748563198 scopus 로고    scopus 로고
    • Clinical application of circulating oxidized low-density lipoprotein biomarker in cardiovascular disease
    • Fraley, A.E., Tsimikas, S., Clinical application of circulating oxidized low-density lipoprotein biomarker in cardiovascular disease. Curr. Opin. Lipidol. 17 (2006), 501–509.
    • (2006) Curr. Opin. Lipidol. , vol.17 , pp. 501-509
    • Fraley, A.E.1    Tsimikas, S.2
  • 109
    • 0032936072 scopus 로고    scopus 로고
    • Presence of oxidized low density lipoprotein in nonrheumatic stenotic aortic valves. Atheroscler
    • Olson, M., Thyberg, J., Nilsson, J., Presence of oxidized low density lipoprotein in nonrheumatic stenotic aortic valves. Atheroscler. Thromb. Vasc. Biol. 19 (1999), 1218–1222.
    • (1999) Thromb. Vasc. Biol. , vol.19 , pp. 1218-1222
    • Olson, M.1    Thyberg, J.2    Nilsson, J.3
  • 111
    • 61949457502 scopus 로고    scopus 로고
    • Oxidized low-denzity lipoproteins trigger endoplastic reticulum stress in vascular cells: prevention by oxygen regulated protein 150 expresion
    • (13)
    • Sanson, M., Auge, N., Vindis, C., Muller, C., Bando, Y., Thiers, J.C., Marachet, M.A., Zarkovic, K., Sawa, Y., Salvayer, R., Negre-Salvayre, A., Oxidized low-denzity lipoproteins trigger endoplastic reticulum stress in vascular cells: prevention by oxygen regulated protein 150 expresion. (13) Circ. Res. 104:3 (2009), 328–336.
    • (2009) Circ. Res. , vol.104 , Issue.3 , pp. 328-336
    • Sanson, M.1    Auge, N.2    Vindis, C.3    Muller, C.4    Bando, Y.5    Thiers, J.C.6    Marachet, M.A.7    Zarkovic, K.8    Sawa, Y.9    Salvayer, R.10    Negre-Salvayre, A.11
  • 113
    • 0030203582 scopus 로고    scopus 로고
    • Atherosclerosis and the vascular biology of aging
    • Bilato, C., Crow, M.T., Atherosclerosis and the vascular biology of aging. Aging 8 (1996), 221–234.
    • (1996) Aging , vol.8 , pp. 221-234
    • Bilato, C.1    Crow, M.T.2
  • 114
    • 0030824354 scopus 로고    scopus 로고
    • Expression of matrix metalloprotinases and their inhibitors in aneurysms and normal aorta
    • Tamarina, N.A., McMillan, W.D., ShLiveli, V.P., Pearce, W.H., Expression of matrix metalloprotinases and their inhibitors in aneurysms and normal aorta. Surgery 122 (1997), 264–271.
    • (1997) Surgery , vol.122 , pp. 264-271
    • Tamarina, N.A.1    McMillan, W.D.2    ShLiveli, V.P.3    Pearce, W.H.4
  • 115
    • 79955586590 scopus 로고    scopus 로고
    • Cellular senescence, vascular disease, and aging: part 2 of a 2-part review: clinical vascular disease in the elderly
    • Kovacic, J.C., Moreno, P., Nabel, E.G., Hachinski, V., Fuster, V., Cellular senescence, vascular disease, and aging: part 2 of a 2-part review: clinical vascular disease in the elderly. Circulation 123:17 (2011), 1900–1910.
    • (2011) Circulation , vol.123 , Issue.17 , pp. 1900-1910
    • Kovacic, J.C.1    Moreno, P.2    Nabel, E.G.3    Hachinski, V.4    Fuster, V.5
  • 116
  • 117
    • 0035978878 scopus 로고    scopus 로고
    • Molecular mechanisms of ageing in connective tissues
    • Bailey, A.J., Molecular mechanisms of ageing in connective tissues. Mech. Ageing Dev. 122:7 (2001), 735–755.
    • (2001) Mech. Ageing Dev. , vol.122 , Issue.7 , pp. 735-755
    • Bailey, A.J.1
  • 118
    • 0842305078 scopus 로고    scopus 로고
    • Age-related changes in the glycation of human aortic elastin
    • Konova, E., Baydanoff, Atanasova, M., Velkova, A., Age-related changes in the glycation of human aortic elastin. Exp. Gerontol. 39:2 (2004), 249–254.
    • (2004) Exp. Gerontol. , vol.39 , Issue.2 , pp. 249-254
    • Konova, E.1    Baydanoff2    Atanasova, M.3    Velkova, A.4
  • 119
    • 18244373458 scopus 로고    scopus 로고
    • Mechanisms, pathophysiology, and therapy of arterial stiffness
    • Zieman, S.J., Melenovsky, V., Kass, D.A., Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler. Thromb. Vasc. Biol. 25:5 (2005), 932–943.
    • (2005) Arterioscler. Thromb. Vasc. Biol. , vol.25 , Issue.5 , pp. 932-943
    • Zieman, S.J.1    Melenovsky, V.2    Kass, D.A.3
  • 120
    • 77956574773 scopus 로고    scopus 로고
    • Pathological aspects of lipid peroxidation
    • Negre-Salvayre, A., Auge, N., Ayala, V., et al. Pathological aspects of lipid peroxidation. Free Radic. Res. 44:10 (2010), 1125–1171.
    • (2010) Free Radic. Res. , vol.44 , Issue.10 , pp. 1125-1171
    • Negre-Salvayre, A.1    Auge, N.2    Ayala, V.3
  • 122
    • 0034885801 scopus 로고    scopus 로고
    • Immunohistochemical detection of lipid peroxidation productes protein-bound acrolein and 4-hydroxynonenal protein adducts, in actinic elastosis of photodamaged skin
    • Tanaka, N., Tajima, S., Ishibasci, A., Uchida, K., Sigematsu, T., Immunohistochemical detection of lipid peroxidation productes protein-bound acrolein and 4-hydroxynonenal protein adducts, in actinic elastosis of photodamaged skin. Arcg. Dermathol. Res. 293 (2001), 363–367.
    • (2001) Arcg. Dermathol. Res. , vol.293 , pp. 363-367
    • Tanaka, N.1    Tajima, S.2    Ishibasci, A.3    Uchida, K.4    Sigematsu, T.5
  • 124
    • 0034753870 scopus 로고    scopus 로고
    • Photoaging: pathogenesis prevention and treatment
    • Kang, S., Fisher, G.J., Voorhees, J.J., Photoaging: pathogenesis prevention and treatment. Clin. Geriatr. Med. 17 (2001), 643–659.
    • (2001) Clin. Geriatr. Med. , vol.17 , pp. 643-659
    • Kang, S.1    Fisher, G.J.2    Voorhees, J.J.3
  • 125
    • 79955006810 scopus 로고    scopus 로고
    • Dose-dependent antioxidant function of resveratrol demonstrated via modulation of reactive oxygen species in normal human skin fibroblasts in vitro
    • Jagdeo, J., Adams, L., Lev-Tov, H., Sieminska, J., Michl, J., Brody, N., Dose-dependent antioxidant function of resveratrol demonstrated via modulation of reactive oxygen species in normal human skin fibroblasts in vitro. J. Drugs Dermatol. 9:12 (2010), 1523–1526.
    • (2010) J. Drugs Dermatol. , vol.9 , Issue.12 , pp. 1523-1526
    • Jagdeo, J.1    Adams, L.2    Lev-Tov, H.3    Sieminska, J.4    Michl, J.5    Brody, N.6
  • 126
    • 80053067267 scopus 로고    scopus 로고
    • Complementary antioxidant function of caffeine and green tea polyphenols in normal human skin fibroblasts
    • Jagdeo, J., Brody, N., Complementary antioxidant function of caffeine and green tea polyphenols in normal human skin fibroblasts. J. Drugs Dermatol. 10:7 (2011), 753–761.
    • (2011) J. Drugs Dermatol. , vol.10 , Issue.7 , pp. 753-761
    • Jagdeo, J.1    Brody, N.2
  • 127
    • 80054761750 scopus 로고    scopus 로고
    • Green tea extract protects human skin fibroblasts from reactive oxygen species induced necrosis
    • Silverberg, J.I., Jagdeo, J., Patel, M., Siegel, D., Brody, N., Green tea extract protects human skin fibroblasts from reactive oxygen species induced necrosis. J. Drugs Dermatol. 10 (2011), 1096–1101.
    • (2011) J. Drugs Dermatol. , vol.10 , pp. 1096-1101
    • Silverberg, J.I.1    Jagdeo, J.2    Patel, M.3    Siegel, D.4    Brody, N.5
  • 128
    • 84870208138 scopus 로고    scopus 로고
    • Caffeine protects human skin fibroblasts from acute reactive oxygen species-induced necrosis
    • Silverberg, J.I., Patel, M., Brody, N., Jagdeo, J., Caffeine protects human skin fibroblasts from acute reactive oxygen species-induced necrosis. J. Drugs Dermatol. 11:11 (2012), 1342–1346.
    • (2012) J. Drugs Dermatol. , vol.11 , Issue.11 , pp. 1342-1346
    • Silverberg, J.I.1    Patel, M.2    Brody, N.3    Jagdeo, J.4
  • 129
    • 0026041040 scopus 로고
    • Active oxygen species as factors in multistage carcinogenesis. Proceedings of the Society for Experimental biology and medicine
    • Witz, G., Active oxygen species as factors in multistage carcinogenesis. Proceedings of the Society for Experimental biology and medicine. Soc. Exp. Biol. Med. 198 (1991), 675–682.
    • (1991) Soc. Exp. Biol. Med. , vol.198 , pp. 675-682
    • Witz, G.1
  • 130
    • 0037411282 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress
    • Uchida, K., 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. Prog. Lipid Res. 42:4 (2003), 318–343.
    • (2003) Prog. Lipid Res. , vol.42 , Issue.4 , pp. 318-343
    • Uchida, K.1
  • 131
    • 0026592966 scopus 로고
    • 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G—-T and A—-C substitutions
    • Cheng, K.C., Cahill, D.S., Kasai, H., Nishimura, S., Loeb, L.A., 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G—-T and A—-C substitutions. J. Biol. Chem. 5 (1991), 166–172.
    • (1991) J. Biol. Chem. , vol.5 , pp. 166-172
    • Cheng, K.C.1    Cahill, D.S.2    Kasai, H.3    Nishimura, S.4    Loeb, L.A.5
  • 132
    • 0347157835 scopus 로고    scopus 로고
    • Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine
    • Matsumura, Y., Ananthaswamy, H.N., Short-term and long-term cellular and molecular events following UV irradiation of skin: implications for molecular medicine. Expert Rev. Mol. Med. 4:26 (2002), 1–22.
    • (2002) Expert Rev. Mol. Med. , vol.4 , Issue.26 , pp. 1-22
    • Matsumura, Y.1    Ananthaswamy, H.N.2
  • 133
    • 0029153955 scopus 로고
    • Action spectrum for Uv-induced lipid-peroxidation in cultured human skin fibroblasts
    • Morliere, P., Moysan, A., Tirache, I., Action spectrum for Uv-induced lipid-peroxidation in cultured human skin fibroblasts. Free Radic. Biol. Med. 19 (1995), 365–371.
    • (1995) Free Radic. Biol. Med. , vol.19 , pp. 365-371
    • Morliere, P.1    Moysan, A.2    Tirache, I.3
  • 134
    • 0035109450 scopus 로고    scopus 로고
    • Green tea polyphenol (−)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress
    • Katiyar, S.K., Afaq, F., Perez, A., Mukhtar, H., Green tea polyphenol (−)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress. Carcinogenesis 22 (2001), 287–294.
    • (2001) Carcinogenesis , vol.22 , pp. 287-294
    • Katiyar, S.K.1    Afaq, F.2    Perez, A.3    Mukhtar, H.4
  • 135
    • 0028350366 scopus 로고
    • Dose-Response Effects of Acute Ultraviolet-Irradiation on Antioxidants and Molecular Markers of Oxidation in Murine Epidermis and Dermis
    • Shindo, Y., Witt, E., Han, D., Packer, L., Dose-Response Effects of Acute Ultraviolet-Irradiation on Antioxidants and Molecular Markers of Oxidation in Murine Epidermis and Dermis. J. Invest Dermatol. 102 (1994), 470–475.
    • (1994) J. Invest Dermatol. , vol.102 , pp. 470-475
    • Shindo, Y.1    Witt, E.2    Han, D.3    Packer, L.4
  • 136
    • 84896807477 scopus 로고    scopus 로고
    • Malondialdehyde-derived epitopes in human skin result from acute exposure to solar UV and occur in nonmelanoma skin cancer tissue
    • Williams, J.D., Bermudez, Y., Uchida, K., Hurst, C.A., Wondrak, G.T., Malondialdehyde-derived epitopes in human skin result from acute exposure to solar UV and occur in nonmelanoma skin cancer tissue. J. Photochem. Photobiol. B. 5:132 (2014), 56–65.
    • (2014) J. Photochem. Photobiol. B. , vol.5 , Issue.132 , pp. 56-65
    • Williams, J.D.1    Bermudez, Y.2    Uchida, K.3    Hurst, C.A.4    Wondrak, G.T.5
  • 137
    • 84900555106 scopus 로고    scopus 로고
    • An immunohistochemical panel to assess ultraviolet radiation associated oxidative skin injury
    • Mamalis, A., Fiadorchanka, N., Adams, L., Heilman, E., Siegel, D., Brody, N., Jagdeo, J., An immunohistochemical panel to assess ultraviolet radiation associated oxidative skin injury. J. Drugs Dermatol. 13:5 (2014), 574–578.
    • (2014) J. Drugs Dermatol. , vol.13 , Issue.5 , pp. 574-578
    • Mamalis, A.1    Fiadorchanka, N.2    Adams, L.3    Heilman, E.4    Siegel, D.5    Brody, N.6    Jagdeo, J.7
  • 140
    • 0038619851 scopus 로고    scopus 로고
    • Oxidative stress in alcoholic and nonalcoholic liver disease
    • U. Leuchster O.F.W. James M. Dancygier Kluver Academic Publisher Dordrecht
    • Cortez-Pinto, H., Oxidative stress in alcoholic and nonalcoholic liver disease. Leuchster, U., James, O.F.W., Dancygier, M., (eds.) Falc symposium 121. Steatohepatitis (NASH and ASH), 2001, Kluver Academic Publisher, Dordrecht, 54–61.
    • (2001) Falc symposium 121. Steatohepatitis (NASH and ASH) , pp. 54-61
    • Cortez-Pinto, H.1
  • 141
    • 0036163870 scopus 로고    scopus 로고
    • Hepatitis C virus proteins: direct link to hepatic oxidative stress, steatosis, carcinogenesis and more
    • Lai, M.M., Hepatitis C virus proteins: direct link to hepatic oxidative stress, steatosis, carcinogenesis and more. Gastroentherology 122 (2002), 568–571.
    • (2002) Gastroentherology , vol.122 , pp. 568-571
    • Lai, M.M.1
  • 142
    • 0034973607 scopus 로고    scopus 로고
    • Cytochromes P450 and metabolism of xenobiotics
    • Anzenbacher, P., Anzenbacherova, E., Cytochromes P450 and metabolism of xenobiotics. Cell. Mol. Life. Sci. 58:5–6 (2001), 737–747.
    • (2001) Cell. Mol. Life. Sci. , vol.58 , Issue.5-6 , pp. 737-747
    • Anzenbacher, P.1    Anzenbacherova, E.2
  • 144
    • 0034746967 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: clinical significance and pathogenesis
    • de Knegt, R.J., Non-alcoholic steatohepatitis: clinical significance and pathogenesis. Scand. J. Gastroenterol. Suppl. 234 (2001), 88–92.
    • (2001) Scand. J. Gastroenterol. Suppl. , vol.234 , pp. 88-92
    • de Knegt, R.J.1
  • 145
    • 0034831067 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis
    • Reid, A.E., Nonalcoholic steatohepatitis. Gastroenterology 121:3 (2001), 710–723.
    • (2001) Gastroenterology , vol.121 , Issue.3 , pp. 710-723
    • Reid, A.E.1
  • 147
    • 0029883448 scopus 로고    scopus 로고
    • Lipid peroxidation: a review of causes, consequences, measurement and dietary influences
    • Benzie, I.F., Lipid peroxidation: a review of causes, consequences, measurement and dietary influences. Int. J. Food Sci. Nutr. 47:3 (1996), 233–261.
    • (1996) Int. J. Food Sci. Nutr. , vol.47 , Issue.3 , pp. 233-261
    • Benzie, I.F.1
  • 148
    • 33744727702 scopus 로고    scopus 로고
    • Studies of oxidative stress in liver disease: important trends in liver resrarch
    • Tanikava, K., Torimura, T., Studies of oxidative stress in liver disease: important trends in liver resrarch. Med. Mol. Morphol. 39 (2006), 22–27.
    • (2006) Med. Mol. Morphol. , vol.39 , pp. 22-27
    • Tanikava, K.1    Torimura, T.2
  • 149
    • 0036307759 scopus 로고    scopus 로고
    • Talidomid prevent alcoholic liver injury in rats through suppression of Kupffer cells sensitation and TNF –a production
    • Enomoto, N., Takei, Y., Hirose, M., Ikejima, K., Miwa, H., Kitamura, T., Sato, N., Talidomid prevent alcoholic liver injury in rats through suppression of Kupffer cells sensitation and TNF –a production. Gastroenterology 123 (2002), 291–300.
    • (2002) Gastroenterology , vol.123 , pp. 291-300
    • Enomoto, N.1    Takei, Y.2    Hirose, M.3    Ikejima, K.4    Miwa, H.5    Kitamura, T.6    Sato, N.7
  • 152
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-a direct role in obesity-linked insulin resistence
    • Hotamisligil, G.S., Shargill, N.S., Spiegelman, B.M., Adipose expression of tumor necrosis factor-a direct role in obesity-linked insulin resistence. Science 259 (1993), 87–91.
    • (1993) Science , vol.259 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 154
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanism of insulin resistence
    • Shulman, G.I., Cellular mechanism of insulin resistence. J. Clin. Invest. 106 (2000), 171–176.
    • (2000) J. Clin. Invest. , vol.106 , pp. 171-176
    • Shulman, G.I.1
  • 155
    • 58149302689 scopus 로고    scopus 로고
    • Iron in NASH, chronic liver diseases and HCC: how much iron is too much?
    • Pietrangelo, A., Iron in NASH, chronic liver diseases and HCC: how much iron is too much?. J. Hepatol. 50 (2009), 249–251.
    • (2009) J. Hepatol. , vol.50 , pp. 249-251
    • Pietrangelo, A.1
  • 156
    • 69249233513 scopus 로고    scopus 로고
    • Role of hepatic iron in non-alcoholic steatohepatitis
    • Sumida, Y., Yoshikawa, T., Okanoue, T., Role of hepatic iron in non-alcoholic steatohepatitis. Hepatol. Res. 39 (2009), 213–222.
    • (2009) Hepatol. Res. , vol.39 , pp. 213-222
    • Sumida, Y.1    Yoshikawa, T.2    Okanoue, T.3
  • 159
    • 0033134774 scopus 로고    scopus 로고
    • Hepatic lipid peroxidation in hereditary hemochromatosis and alcoholic liver injury
    • Niemela, O., Parkkila, S., Briton, R.S., Brunt, E., Janney, C., Bacon, B., Hepatic lipid peroxidation in hereditary hemochromatosis and alcoholic liver injury. J. Lab Med. 133 (1999), 451–460.
    • (1999) J. Lab Med. , vol.133 , pp. 451-460
    • Niemela, O.1    Parkkila, S.2    Briton, R.S.3    Brunt, E.4    Janney, C.5    Bacon, B.6
  • 160
    • 0030820474 scopus 로고    scopus 로고
    • Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in liver of rats with alcoholic liver disease
    • Li, C.J., Nanji, A.A., Siakotos, A.N., Lin, R.C., Acetaldehyde-modified and 4-hydroxynonenal-modified proteins in liver of rats with alcoholic liver disease. Hepatology 26 (1997), 650–657.
    • (1997) Hepatology , vol.26 , pp. 650-657
    • Li, C.J.1    Nanji, A.A.2    Siakotos, A.N.3    Lin, R.C.4
  • 161
    • 0037971533 scopus 로고    scopus 로고
    • Immunohistochemical characterisation of hepatic malondialdehyde and 4-hydoxynonenale modified proteins during early stage of ethanol-induced liver injury
    • Sampey, B.P., Korourian, S., Ronis, M.J., Badger, T.M., Petersen, D.R., Immunohistochemical characterisation of hepatic malondialdehyde and 4-hydoxynonenale modified proteins during early stage of ethanol-induced liver injury. Alcohol Clin. Exp. Res. 27 (2003), 1015–1022.
    • (2003) Alcohol Clin. Exp. Res. , vol.27 , pp. 1015-1022
    • Sampey, B.P.1    Korourian, S.2    Ronis, M.J.3    Badger, T.M.4    Petersen, D.R.5
  • 162
    • 40049104518 scopus 로고    scopus 로고
    • 4-Hydroxynonenal-protein adducts: a reliable biomarker of lipid oxidation in liver diseases
    • Poli, G., Biasi, F., Leonarduzzi, G., 4-Hydroxynonenal-protein adducts: a reliable biomarker of lipid oxidation in liver diseases. Mol. Asp. Med. 29 (2008), 67–71.
    • (2008) Mol. Asp. Med. , vol.29 , pp. 67-71
    • Poli, G.1    Biasi, F.2    Leonarduzzi, G.3
  • 163
    • 0037393271 scopus 로고    scopus 로고
    • Pathological significance of oxidative cellular damage in human alcoholic liver disease
    • Seki, S., Kitada, T., Sakaguachi, H., Nakatani, K., Wakasa, K., Pathological significance of oxidative cellular damage in human alcoholic liver disease. Histopathology 42 (2003), 365–371.
    • (2003) Histopathology , vol.42 , pp. 365-371
    • Seki, S.1    Kitada, T.2    Sakaguachi, H.3    Nakatani, K.4    Wakasa, K.5
  • 164
    • 61849087294 scopus 로고    scopus 로고
    • Elevated oxidative stress, iron accumulation around microvessels and increased 4-hydroxynonenal immunostaining in zone 1 of the liver acinus in hypercholesterolemic rabbits
    • Ong, W.Y., Jenner, A.M., Pan, N., Ong, C.N., Halliwell, B., Elevated oxidative stress, iron accumulation around microvessels and increased 4-hydroxynonenal immunostaining in zone 1 of the liver acinus in hypercholesterolemic rabbits. Free Radic. Res. 43 (2009), 241–249.
    • (2009) Free Radic. Res. , vol.43 , pp. 241-249
    • Ong, W.Y.1    Jenner, A.M.2    Pan, N.3    Ong, C.N.4    Halliwell, B.5
  • 165
    • 0035991444 scopus 로고    scopus 로고
    • In situ lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver disease
    • Seki, S., Kitada, T., Yamada, T., Sakaguchi, H., Nakatani, K., Wakasa, K., In situ lipid peroxidation and oxidative DNA damage in non-alcoholic fatty liver disease. J. Hepatol. 37 (2002), 56–62.
    • (2002) J. Hepatol. , vol.37 , pp. 56-62
    • Seki, S.1    Kitada, T.2    Yamada, T.3    Sakaguchi, H.4    Nakatani, K.5    Wakasa, K.6
  • 167
    • 84997327239 scopus 로고    scopus 로고
    • Huiyong in mitochondrial control of apoptosis through modulation of cardiolipin oxidation in hepatocellular carcinoma: a novel link between oxidative stress and cancer
    • Zhong, H., Xiao, M., Zarkovic, K., Zhu, M., Sa, R., Lu, J., Tao, Y., Chen, Q., Xia, L., Cheng, S., Waeg, G., Zarkovic, N., Huiyong in mitochondrial control of apoptosis through modulation of cardiolipin oxidation in hepatocellular carcinoma: a novel link between oxidative stress and cancer. Free Radic. Biol. Med. 102 (2017), 67–76.
    • (2017) Free Radic. Biol. Med. , vol.102 , pp. 67-76
    • Zhong, H.1    Xiao, M.2    Zarkovic, K.3    Zhu, M.4    Sa, R.5    Lu, J.6    Tao, Y.7    Chen, Q.8    Xia, L.9    Cheng, S.10    Waeg, G.11    Zarkovic, N.12
  • 169
    • 84882722472 scopus 로고    scopus 로고
    • Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets
    • Biasi, F., Leonarduzzi, G., Oteiza, P.I., Poli, G., Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets. Antioxid. Redox Signal. 19 (2013), 1711–1747.
    • (2013) Antioxid. Redox Signal. , vol.19 , pp. 1711-1747
    • Biasi, F.1    Leonarduzzi, G.2    Oteiza, P.I.3    Poli, G.4
  • 170
    • 0025854965 scopus 로고
    • Superoxide production by Crohn's disease neutrophils
    • Curran, F.T., Allan, R.N., Keighley, M.R., Superoxide production by Crohn's disease neutrophils. Gut 32 (1991), 399–402.
    • (1991) Gut , vol.32 , pp. 399-402
    • Curran, F.T.1    Allan, R.N.2    Keighley, M.R.3
  • 171
    • 74049155086 scopus 로고    scopus 로고
    • Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naive and treated Crohn's disease
    • Beltran, B., Nos, P., Dasi, F., Iborra, M., Bastida, G., Martinez, M., O'Connor, J.E., Saez, G., Moret, I., Ponce, J., Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naive and treated Crohn's disease. Inflamm. Bowel Dis. 16 (2010), 76–86.
    • (2010) Inflamm. Bowel Dis. , vol.16 , pp. 76-86
    • Beltran, B.1    Nos, P.2    Dasi, F.3    Iborra, M.4    Bastida, G.5    Martinez, M.6    O'Connor, J.E.7    Saez, G.8    Moret, I.9    Ponce, J.10
  • 172
    • 84868308836 scopus 로고    scopus 로고
    • The detrimental effect of nitric oxide on tissue is associated with inflammatory events in the vascular endothelium and neutrophils in mice with dextran sodium sulfate-induced colitis
    • Yasukava, K., Tokuda, H., Tun, X., Utsumi, H., Yamada, K., The detrimental effect of nitric oxide on tissue is associated with inflammatory events in the vascular endothelium and neutrophils in mice with dextran sodium sulfate-induced colitis. Free Radic. Res. 49 (2012), 1427–1436.
    • (2012) Free Radic. Res. , vol.49 , pp. 1427-1436
    • Yasukava, K.1    Tokuda, H.2    Tun, X.3    Utsumi, H.4    Yamada, K.5
  • 173
    • 0030861590 scopus 로고    scopus 로고
    • Interaction of antigens and antibiotics at mucosal surface
    • Lamm, M.E., Interaction of antigens and antibiotics at mucosal surface. Annu. Rev. Microbiol. 51 (1997), 311–340.
    • (1997) Annu. Rev. Microbiol. , vol.51 , pp. 311-340
    • Lamm, M.E.1
  • 175
    • 22144454310 scopus 로고    scopus 로고
    • Rapid increase in serum lipid peroxide 4-hydroxynonenal(HNE) trough monocite NADPH oxidase in early endo-toxemia
    • Kimura, H., Lui, S., Yamada, S., Uchida, K., Matsumoto, K., Mukaida, M., Yoshida, K., Rapid increase in serum lipid peroxide 4-hydroxynonenal(HNE) trough monocite NADPH oxidase in early endo-toxemia. Free Radic. Res. 39 (2004), 845–851.
    • (2004) Free Radic. Res. , vol.39 , pp. 845-851
    • Kimura, H.1    Lui, S.2    Yamada, S.3    Uchida, K.4    Matsumoto, K.5    Mukaida, M.6    Yoshida, K.7
  • 177
    • 41049101193 scopus 로고    scopus 로고
    • The distribution of 4-hydroxynonenal-modified proteins in gastric mucosa of duodenal peptic ulcer patients
    • Yelisyeyeva, O., Cherkas, A., Zarkovic, K., Semen, K., Kaminskyy, D., Waeg, G., Zarkovic, N., The distribution of 4-hydroxynonenal-modified proteins in gastric mucosa of duodenal peptic ulcer patients. Free Radic. Res. 42 (2008), 205–211.
    • (2008) Free Radic. Res. , vol.42 , pp. 205-211
    • Yelisyeyeva, O.1    Cherkas, A.2    Zarkovic, K.3    Semen, K.4    Kaminskyy, D.5    Waeg, G.6    Zarkovic, N.7
  • 180
    • 84871310462 scopus 로고    scopus 로고
    • Reactive oxygen species mediated Cr (VI)-induced S phase arrest through p53 in human colon cancer cells
    • Sun, L., Wang, X., Yao, H., Li, W., Son, Y.O., Luo, J., Liu, J., Zhang, Z., Reactive oxygen species mediated Cr (VI)-induced S phase arrest through p53 in human colon cancer cells. J. Environ. Pathol. Toxicol. Oncol. 31 (2012), 95–107.
    • (2012) J. Environ. Pathol. Toxicol. Oncol. , vol.31 , pp. 95-107
    • Sun, L.1    Wang, X.2    Yao, H.3    Li, W.4    Son, Y.O.5    Luo, J.6    Liu, J.7    Zhang, Z.8
  • 181
    • 0032124878 scopus 로고    scopus 로고
    • 4-hydroxunonenal modified the effects of serum growth factors on the expression of the c-fos proto-oncogen and proliferation of HeLa carcinoma cells
    • Kreuzer, T., Grube, R., Zarkovic, N., Schaur, R.J., 4-hydroxunonenal modified the effects of serum growth factors on the expression of the c-fos proto-oncogen and proliferation of HeLa carcinoma cells. Free Radic. Biol. Med. 25 (1998), 42–49.
    • (1998) Free Radic. Biol. Med. , vol.25 , pp. 42-49
    • Kreuzer, T.1    Grube, R.2    Zarkovic, N.3    Schaur, R.J.4
  • 182
    • 84936746182 scopus 로고    scopus 로고
    • Overview on major lipid peroxidation bioactive factor 4-hydroxynonenal as pluripotent growth regulating factor
    • Milkovic, L., Cipak Gasparovic, A., Zarkovic, N., Overview on major lipid peroxidation bioactive factor 4-hydroxynonenal as pluripotent growth regulating factor. Free Radic. Res. 49 (2015), 850–860.
    • (2015) Free Radic. Res. , vol.49 , pp. 850-860
    • Milkovic, L.1    Cipak Gasparovic, A.2    Zarkovic, N.3
  • 184
    • 33744780209 scopus 로고    scopus 로고
    • Tissue distribution of lipid peroxidation product acrolein in human colon carcinogenesis
    • Zarkovic, K., Uchida, K., Kolenc, D., Hlupic, L., Zarkovic, N., Tissue distribution of lipid peroxidation product acrolein in human colon carcinogenesis. Free Radic. Res. 40 (2006), 543–552.
    • (2006) Free Radic. Res. , vol.40 , pp. 543-552
    • Zarkovic, K.1    Uchida, K.2    Kolenc, D.3    Hlupic, L.4    Zarkovic, N.5
  • 186
    • 33745852197 scopus 로고    scopus 로고
    • JNK up-regulation as a key event in the pro-apoptotic interaction between TGF-ß1 and 4-hydroxynonenal in colon mucosa
    • Biasi, F., Vizio, B., Mascia, C., Gaia, E., Zarkovic, N., Chiarpotto, E., Leonarduzzi, G., Poli, G., JNK up-regulation as a key event in the pro-apoptotic interaction between TGF-ß1 and 4-hydroxynonenal in colon mucosa. Free Radic. Biol. Med. 40 (2006), 443–454.
    • (2006) Free Radic. Biol. Med. , vol.40 , pp. 443-454
    • Biasi, F.1    Vizio, B.2    Mascia, C.3    Gaia, E.4    Zarkovic, N.5    Chiarpotto, E.6    Leonarduzzi, G.7    Poli, G.8
  • 188
    • 28644440011 scopus 로고    scopus 로고
    • The influence of 4-hydroxy-2-nonenal on proliferation, differentiation and apoptosis of human osteosarcoma cells
    • Sunjic, S.B., Cipak, A., Rabuzin, F., Wildburger, R., et al. The influence of 4-hydroxy-2-nonenal on proliferation, differentiation and apoptosis of human osteosarcoma cells. Biofactors 24:1–4 (2005), 141–148.
    • (2005) Biofactors , vol.24 , Issue.1-4 , pp. 141-148
    • Sunjic, S.B.1    Cipak, A.2    Rabuzin, F.3    Wildburger, R.4
  • 189
    • 33846807884 scopus 로고    scopus 로고
    • Differential effect of 4-hydroxynonenal on normal and malignant mesenchimal cells
    • Borovic, S., Cipak, A., Meinitzer, A., Kejla, Z., Perovic, D., Waeg, G., Zarkovic, N., Differential effect of 4-hydroxynonenal on normal and malignant mesenchimal cells. Redox Rep. 207 (2007), 50–54.
    • (2007) Redox Rep. , vol.207 , pp. 50-54
    • Borovic, S.1    Cipak, A.2    Meinitzer, A.3    Kejla, Z.4    Perovic, D.5    Waeg, G.6    Zarkovic, N.7
  • 190
    • 84906786561 scopus 로고    scopus 로고
    • Effects of Cu-doped 45S5 bioactive glass on the lipid peroxidation-associated growth of human osteoblast-like cells in vitro
    • Milkovic, L., Hoppe, A., Detsch, R., Boccaccini, A.R., Zarkovic, N., Effects of Cu-doped 45S5 bioactive glass on the lipid peroxidation-associated growth of human osteoblast-like cells in vitro. J. Biomed. Mater. Res.: Part A 102 (2014), 3556–3561.
    • (2014) J. Biomed. Mater. Res.: Part A , vol.102 , pp. 3556-3561
    • Milkovic, L.1    Hoppe, A.2    Detsch, R.3    Boccaccini, A.R.4    Zarkovic, N.5
  • 191
    • 84940203724 scopus 로고    scopus 로고
    • The lack of 4-hydroxynonenal in otosclerotic bone tissue in Ethiopian population
    • Rudic, M., Wagner, R., Willkinson, E., et al. The lack of 4-hydroxynonenal in otosclerotic bone tissue in Ethiopian population. Eur. Arch. Otorhinolaryngol. 272:10 (2015), 2783–2789.
    • (2015) Eur. Arch. Otorhinolaryngol. , vol.272 , Issue.10 , pp. 2783-2789
    • Rudic, M.1    Wagner, R.2    Willkinson, E.3
  • 192
    • 84874591556 scopus 로고    scopus 로고
    • The effects of angiotensin II and the oxidative stress mediator 4-hydroxynonenal on human osteoblast-like cell growth: possible relevance to otosclerosis
    • Rudic, M., Milković, L., Žarković, K., et al. The effects of angiotensin II and the oxidative stress mediator 4-hydroxynonenal on human osteoblast-like cell growth: possible relevance to otosclerosis. Free Radic. Biol. Med. 57 (2013), 22–28.
    • (2013) Free Radic. Biol. Med. , vol.57 , pp. 22-28
    • Rudic, M.1    Milković, L.2    Žarković, K.3
  • 193
    • 0028169262 scopus 로고
    • Formation of 8-hydroxy-2-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in human renal-cell carcinoma
    • Okamoto, K., Toyokuni, S., Uchida, K., et al. Formation of 8-hydroxy-2-deoxyguanosine and 4-hydroxy-2-nonenal-modified proteins in human renal-cell carcinoma. Int.J. Cancer 58 (1994), 825–829.
    • (1994) Int.J. Cancer , vol.58 , pp. 825-829
    • Okamoto, K.1    Toyokuni, S.2    Uchida, K.3
  • 194
    • 0032867803 scopus 로고    scopus 로고
    • Localization of hydroxynonenal protein adducts in normal human kidney and selected human kidney cancers
    • Oberley, T.D., Toyokuni, S., Szweda, A.I., Localization of hydroxynonenal protein adducts in normal human kidney and selected human kidney cancers. Free Radic. Biol. Med. 27:5–6 (1999), 695–703.
    • (1999) Free Radic. Biol. Med. , vol.27 , Issue.5-6 , pp. 695-703
    • Oberley, T.D.1    Toyokuni, S.2    Szweda, A.I.3
  • 196
    • 70350767329 scopus 로고    scopus 로고
    • Oxidative stress in prostate hypertrophy and carcinogenesis
    • Przybyszewski, W.M., Rzeszowska-Wolny, J., Oxidative stress in prostate hypertrophy and carcinogenesis. Postepy Hig. Med. Dosw. 63 (2009), 340–350.
    • (2009) Postepy Hig. Med. Dosw. , vol.63 , pp. 340-350
    • Przybyszewski, W.M.1    Rzeszowska-Wolny, J.2
  • 197
    • 77951293458 scopus 로고    scopus 로고
    • Lipid peroxidation product acrolein as a predictive biomarker of prostate carcinoma relapse after radical surgery
    • Custovic, Z., Zarkovic, K., Cindric, M., Cipak, A., et al. Lipid peroxidation product acrolein as a predictive biomarker of prostate carcinoma relapse after radical surgery. Free Radic. Res. 44 (2010), 497–504.
    • (2010) Free Radic. Res. , vol.44 , pp. 497-504
    • Custovic, Z.1    Zarkovic, K.2    Cindric, M.3    Cipak, A.4
  • 198
    • 0000590881 scopus 로고
    • Identifi cation of the ami- noaldehydes produced by the oxidation of spermine and spermidine with purifi ed plasma amine oxidase
    • Tabor, C.W., Tabor, H., Bachrach, U., Identifi cation of the ami- noaldehydes produced by the oxidation of spermine and spermidine with purifi ed plasma amine oxidase. J. Biol. Chem. 239 (1964), 2194–2203.
    • (1964) J. Biol. Chem. , vol.239 , pp. 2194-2203
    • Tabor, C.W.1    Tabor, H.2    Bachrach, U.3
  • 199
    • 0032945381 scopus 로고    scopus 로고
    • Acrolein cytotoxicity and glutathione depletion in n-3 fatty acid sensitive- and resistant human tumor cells
    • Rudra, P.K., Krokan, H.E., Acrolein cytotoxicity and glutathione depletion in n-3 fatty acid sensitive- and resistant human tumor cells. Anticancer Res. 19 (1999), 461–469.
    • (1999) Anticancer Res. , vol.19 , pp. 461-469
    • Rudra, P.K.1    Krokan, H.E.2
  • 200
    • 0029005167 scopus 로고
    • Thyroidal extracellular glutathione peroxidise: a potential regulator of thyroid-hormone synthesis
    • Howie, A.F., Walker, S.W., Akesson, B., Arthur, J.R., Beckett, G.J., Thyroidal extracellular glutathione peroxidise: a potential regulator of thyroid-hormone synthesis. Biochem. J. 308:Pt 3 (1995), 713–717.
    • (1995) Biochem. J. , vol.308 , pp. 713-717
    • Howie, A.F.1    Walker, S.W.2    Akesson, B.3    Arthur, J.R.4    Beckett, G.J.5
  • 201
    • 77952785713 scopus 로고    scopus 로고
    • Levels of oxidative damage and lipid peroxidation in thyroid neoplasia
    • Young, O., Crotty, T., O Connell, R., et al. Levels of oxidative damage and lipid peroxidation in thyroid neoplasia. Head Neck 32 (2010), 750–756.
    • (2010) Head Neck , vol.32 , pp. 750-756
    • Young, O.1    Crotty, T.2    O Connell, R.3
  • 202
    • 77958186867 scopus 로고    scopus 로고
    • Protein modifications as potential biomarkers in breast cancer
    • Jin, H., Zangar, R.C., Protein modifications as potential biomarkers in breast cancer. Biomark. Insights, 2009, 191–200.
    • (2009) Biomark. Insights , pp. 191-200
    • Jin, H.1    Zangar, R.C.2
  • 203
    • 84921787879 scopus 로고    scopus 로고
    • 4-Hydroxynonenal promotes growth and angiogenesis of breast cancer cells through HIF-1ɑ stabilization
    • Yao-Ping, L., Fu-Guo, T., Peng-Cheng, S., et al. 4-Hydroxynonenal promotes growth and angiogenesis of breast cancer cells through HIF-1ɑ stabilization. Asian Pac. J. Cancer Prev. 15 (2014), 10151–10156.
    • (2014) Asian Pac. J. Cancer Prev. , vol.15 , pp. 10151-10156
    • Yao-Ping, L.1    Fu-Guo, T.2    Peng-Cheng, S.3
  • 204
    • 79956122656 scopus 로고    scopus 로고
    • Divergent behaviour of oxidative stress markers 8-hydroxydeoxyguanosine (8-OHdG) and 4-hydroxy-2nonenal (HNE) in breast carcinogenesis
    • Karihtala, P., Kauppila, S., Puistola, U., JukkolaVuorinen, A., Divergent behaviour of oxidative stress markers 8-hydroxydeoxyguanosine (8-OHdG) and 4-hydroxy-2nonenal (HNE) in breast carcinogenesis. Histopathology 58 (2011), 854–862.
    • (2011) Histopathology , vol.58 , pp. 854-862
    • Karihtala, P.1    Kauppila, S.2    Puistola, U.3    JukkolaVuorinen, A.4
  • 205
    • 51349166203 scopus 로고    scopus 로고
    • Lipid peroxidation and antioxidant status in patients with breast cancer
    • Rajneesh, C.P., Manimaran, A., Sasikala, K.R., Adaikappan, P., Lipid peroxidation and antioxidant status in patients with breast cancer. Singap. Med. J. 49 (2008), 640–643.
    • (2008) Singap. Med. J. , vol.49 , pp. 640-643
    • Rajneesh, C.P.1    Manimaran, A.2    Sasikala, K.R.3    Adaikappan, P.4
  • 206
    • 0034480353 scopus 로고    scopus 로고
    • Glutathione and its metabolizing enzymes in patients with different benign and malignant diseases
    • Abou Ghalia, A.H., Fouad, I.M., Glutathione and its metabolizing enzymes in patients with different benign and malignant diseases. Clin. Biochem. 33 (2000), 657–662.
    • (2000) Clin. Biochem. , vol.33 , pp. 657-662
    • Abou Ghalia, A.H.1    Fouad, I.M.2
  • 207
    • 77949542434 scopus 로고    scopus 로고
    • 8-hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer
    • Sova, H., Jukkola-Vuorinen, A., Puistola, U., Kauppila, S., Karihtala, P., 8-hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer. Br. J. Cancer 102 (2010), 1018–1023.
    • (2010) Br. J. Cancer , vol.102 , pp. 1018-1023
    • Sova, H.1    Jukkola-Vuorinen, A.2    Puistola, U.3    Kauppila, S.4    Karihtala, P.5
  • 210
    • 0002776555 scopus 로고    scopus 로고
    • Guidelines for the management of chronic obsynthesis in lung inflammation
    • British Thoracic Society, Guidelines for the management of chronic obsynthesis in lung inflammation. Thorax 52 (1997), S1–S28.
    • (1997) Thorax , vol.52 , pp. S1-S28
    • British Thoracic Society1
  • 211
    • 0029740875 scopus 로고    scopus 로고
    • Role of oxidants/antioxidants in smoking-induced
    • Rahman, I., MacNee, W., Role of oxidants/antioxidants in smoking-induced. Free Radic. Biol. Med. 21 (1996), 669–681.
    • (1996) Free Radic. Biol. Med. , vol.21 , pp. 669-681
    • Rahman, I.1    MacNee, W.2
  • 212
    • 0037102347 scopus 로고    scopus 로고
    • 4-Hydroxy-2nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease
    • Rahman, I., van Schadewijk, A.A., Crowther, A.J., Hiemstra, P.S., Stolk, J., MacNee, W., et al. 4-Hydroxy-2nonenal, a specific lipid peroxidation product, is elevated in lungs of patients with chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 166 (2002), 490–495.
    • (2002) Am. J. Respir. Crit. Care Med. , vol.166 , pp. 490-495
    • Rahman, I.1    van Schadewijk, A.A.2    Crowther, A.J.3    Hiemstra, P.S.4    Stolk, J.5    MacNee, W.6
  • 214
    • 0021185122 scopus 로고
    • A novel biologically active seleno-organic compaund- glutation peroxidase- like activity in vitro and antioxidant capacity of PZ 51 (ebselen)
    • Muller, A., Cadanas, E., Graf, P., Sies, H., A novel biologically active seleno-organic compaund- glutation peroxidase- like activity in vitro and antioxidant capacity of PZ 51 (ebselen). Biochem. Pharmacol. 33 (1984), 3235–3239.
    • (1984) Biochem. Pharmacol. , vol.33 , pp. 3235-3239
    • Muller, A.1    Cadanas, E.2    Graf, P.3    Sies, H.4
  • 215
    • 79955479655 scopus 로고    scopus 로고
    • PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adducts accumulation: correlation with peripheral nerve function
    • Lupachyk, S., Shevalye, H., Maksimichyk, J., Drel, V.R., Obrosova, I.G., PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adducts accumulation: correlation with peripheral nerve function. Free Radic. Biol. Med. 50 (2011), 1400–1409.
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 1400-1409
    • Lupachyk, S.1    Shevalye, H.2    Maksimichyk, J.3    Drel, V.R.4    Obrosova, I.G.5
  • 216
    • 77957764802 scopus 로고    scopus 로고
    • A pyrazole curcumin derivative restores membrane homeostasis disrupted after brain trauma
    • Sharma, S., Ying, Z., Gomez-Pinilla, F., A pyrazole curcumin derivative restores membrane homeostasis disrupted after brain trauma. Exp. Neurol. 226 (2010), 191–199.
    • (2010) Exp. Neurol. , vol.226 , pp. 191-199
    • Sharma, S.1    Ying, Z.2    Gomez-Pinilla, F.3


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