-
1
-
-
0030593939
-
Mechanisms of muscle wasting: The role of the ubiquitin-proteasome system
-
Mitch WE, Goldberg AL: Mechanisms of muscle wasting: The role of the ubiquitin-proteasome system. N Engl J Med 335: 1897-1905, 1996
-
(1996)
N Engl J Med
, vol.335
, pp. 1897-1905
-
-
Mitch, W.E.1
Goldberg, A.L.2
-
2
-
-
0027980319
-
Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class 1 molecules
-
Rock KL, Gramm C, Rothstein L, Clark K, Stein R, Dick L, Hwang D, Goldberg AL: Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class 1 molecules. Cell 78: 761-771, 1994
-
(1994)
Cell
, vol.78
, pp. 761-771
-
-
Rock, K.L.1
Gramm, C.2
Rothstein, L.3
Clark, K.4
Stein, R.5
Dick, L.6
Hwang, D.7
Goldberg, A.L.8
-
3
-
-
20344387475
-
Autophagy: Dual roles in life and death?
-
Baehrecke EH: Autophagy: Dual roles in life and death? Nat Rev Mol Cell Biol 6: 505-510, 2005
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 505-510
-
-
Baehrecke, E.H.1
-
4
-
-
0023665218
-
Amino acid and hormonal control of macromolecular turnover in perfused rat liver. Evidence for selective autophagy
-
Lardeux BR, Mortimore GE: Amino acid and hormonal control of macromolecular turnover in perfused rat liver. Evidence for selective autophagy. J Biol Chem 262: 14514-14519, 1987
-
(1987)
J Biol Chem
, vol.262
, pp. 14514-14519
-
-
Lardeux, B.R.1
Mortimore, G.E.2
-
5
-
-
0021191576
-
The role of increased proteolysis in the atrophy and arrest of cell division in fibroblasts following serum deprivation
-
Gronostajski RM, Goldberg AL, Pardee AB: The role of increased proteolysis in the atrophy and arrest of cell division in fibroblasts following serum deprivation. J Cell Biol 121: 189-198, 1984
-
(1984)
J Cell Biol
, vol.121
, pp. 189-198
-
-
Gronostajski, R.M.1
Goldberg, A.L.2
Pardee, A.B.3
-
6
-
-
0038337815
-
The calpain system
-
Goll DE, Thompson VF, Li H, Wei W, Cong J: The calpain system. Physiol Rev 83: 731-801, 2003
-
(2003)
Physiol Rev
, vol.83
, pp. 731-801
-
-
Goll, D.E.1
Thompson, V.F.2
Li, H.3
Wei, W.4
Cong, J.5
-
7
-
-
0030702084
-
Caspases: Intracellular signaling by proteolysis
-
Salvesen GS, Dixit VM: Caspases: Intracellular signaling by proteolysis. Cell 91: 443-446, 1997
-
(1997)
Cell
, vol.91
, pp. 443-446
-
-
Salvesen, G.S.1
Dixit, V.M.2
-
8
-
-
0036083396
-
The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction
-
Glickman MH, Ciechanover A: The ubiquitin-proteasome proteolytic pathway: Destruction for the sake of construction. Physiol Rev 82: 373-428, 2002
-
(2002)
Physiol Rev
, vol.82
, pp. 373-428
-
-
Glickman, M.H.1
Ciechanover, A.2
-
9
-
-
0842303313
-
Back to the future with ubiquitin
-
Pickart CM: Back to the future with ubiquitin. Cell 116: 181-190, 2004
-
(2004)
Cell
, vol.116
, pp. 181-190
-
-
Pickart, C.M.1
-
10
-
-
0032488846
-
The proteasome: Paradigm of a self-compartmentalizing protease
-
Baumeister W, Walz J, Zuhl F, Seemuller E: The proteasome: Paradigm of a self-compartmentalizing protease. Cell 92: 367-380, 1998
-
(1998)
Cell
, vol.92
, pp. 367-380
-
-
Baumeister, W.1
Walz, J.2
Zuhl, F.3
Seemuller, E.4
-
11
-
-
0037335034
-
How the ubiquitin-proteasome system controls transcription
-
Muratani M, Tansey WP: How the ubiquitin-proteasome system controls transcription. Nat Rev Mol Cell Biol 4: 192-201, 2003
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, pp. 192-201
-
-
Muratani, M.1
Tansey, W.P.2
-
12
-
-
27744495040
-
A putative stimulatory role for activator turnover in gene expression
-
Lipford JR, Smith GT, Chi Y, Deshaies RJ: A putative stimulatory role for activator turnover in gene expression. Nature 438: 113-116, 2005
-
(2005)
Nature
, vol.438
, pp. 113-116
-
-
Lipford, J.R.1
Smith, G.T.2
Chi, Y.3
Deshaies, R.J.4
-
13
-
-
0034084163
-
Phosphorylation meets ubiquitination: The control of NF-kappaB activity
-
Karin M, Ben-Neriah Y: Phosphorylation meets ubiquitination: The control of NF-kappaB activity. Annu Rev Immunol 18: 621-663, 2000
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 621-663
-
-
Karin, M.1
Ben-Neriah, Y.2
-
14
-
-
0028858161
-
Multiple proteolytic systems, including the proteasome contribute CFTR processing
-
Jensen TJ, Loo MA, Find S, Williams DB, Goldberg AL, Riordan JR: Multiple proteolytic systems, including the proteasome contribute CFTR processing. Cell 83: 129-135, 1995
-
(1995)
Cell
, vol.83
, pp. 129-135
-
-
Jensen, T.J.1
Loo, M.A.2
Find, S.3
Williams, D.B.4
Goldberg, A.L.5
Riordan, J.R.6
-
15
-
-
0028840915
-
Degradation of CFTR by the ubiquitin-proteasome pathway
-
Ward CL, Omura S, Kopito RR: Degradation of CFTR by the ubiquitin-proteasome pathway. Cell 83: 121-127, 1995
-
(1995)
Cell
, vol.83
, pp. 121-127
-
-
Ward, C.L.1
Omura, S.2
Kopito, R.R.3
-
16
-
-
23144451257
-
ERAD: The long road to destruction
-
Meusser B, Hirsch C, Jarosch E, Sommer T: ERAD: The long road to destruction. Nat Cell Biol 7: 766-772, 2005
-
(2005)
Nat Cell Biol
, vol.7
, pp. 766-772
-
-
Meusser, B.1
Hirsch, C.2
Jarosch, E.3
Sommer, T.4
-
17
-
-
0141442586
-
Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins
-
Hicke L, Dunn R: Regulation of membrane protein transport by ubiquitin and ubiquitin-binding proteins. Annu Rev Cell Dev Biol 19: 141-172, 2003
-
(2003)
Annu Rev Cell Dev Biol
, vol.19
, pp. 141-172
-
-
Hicke, L.1
Dunn, R.2
-
19
-
-
0020479562
-
The mechanism of ubiquitin activating enzyme. A kinetic and equilibrium analysis
-
Haas AL, Rose IA: The mechanism of ubiquitin activating enzyme. A kinetic and equilibrium analysis. J Biol Chem 257: 10329-10337, 1982
-
(1982)
J Biol Chem
, vol.257
, pp. 10329-10337
-
-
Haas, A.L.1
Rose, I.A.2
-
20
-
-
0025960565
-
Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1
-
Handley PM, Mueckler M, Siegel NR, Ciechanover A, Schwartz AL: Molecular cloning, sequence, and tissue distribution of the human ubiquitin-activating enzyme E1. Proc Natl Acad Sci U S A 88: 258-262, 1991
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 258-262
-
-
Handley, P.M.1
Mueckler, M.2
Siegel, N.R.3
Ciechanover, A.4
Schwartz, A.L.5
-
21
-
-
0027053491
-
The ubiquitin-conjugation system
-
Jentsch S: The ubiquitin-conjugation system. Annu Rev Genet 26: 179-207, 1992
-
(1992)
Annu Rev Genet
, vol.26
, pp. 179-207
-
-
Jentsch, S.1
-
22
-
-
0034308251
-
The lore of the RINGs: Substrate recognition and catalysis by ubiquitin ligases
-
Jackson PK, Eldridge AG, Freed E, Furstenthal L, Hsu JY, Kaiser BK, Reimann JD: The lore of the RINGs: Substrate recognition and catalysis by ubiquitin ligases. Trends Cell Biol 10: 429-439, 2000
-
(2000)
Trends Cell Biol
, vol.10
, pp. 429-439
-
-
Jackson, P.K.1
Eldridge, A.G.2
Freed, E.3
Furstenthal, L.4
Hsu, J.Y.5
Kaiser, B.K.6
Reimann, J.D.7
-
23
-
-
1842591240
-
The Nedd4 family of E3 ubiquitin ligases: Functional diversity within a common modular architecture
-
Ingham RJ, Gish G, Pawson T: The Nedd4 family of E3 ubiquitin ligases: Functional diversity within a common modular architecture. Oncogene 23: 1972-1984, 2004
-
(2004)
Oncogene
, vol.23
, pp. 1972-1984
-
-
Ingham, R.J.1
Gish, G.2
Pawson, T.3
-
24
-
-
0028898424
-
Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade
-
Scheffner M, Nuber U, Huibregtse JM: Protein ubiquitination involving an E1-E2-E3 enzyme ubiquitin thioester cascade. Nature 373: 81-83, 1995
-
(1995)
Nature
, vol.373
, pp. 81-83
-
-
Scheffner, M.1
Nuber, U.2
Huibregtse, J.M.3
-
25
-
-
0029036701
-
A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase
-
Huibregtse JM, Scheffner M, Beaudenon S, Howley PM: A family of proteins structurally and functionally related to the E6-AP ubiquitin-protein ligase. Proc Natl Acad Sci U S A 92: 5249, 1995
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 5249
-
-
Huibregtse, J.M.1
Scheffner, M.2
Beaudenon, S.3
Howley, P.M.4
-
26
-
-
0030879482
-
Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons
-
Albrecht U, Sutcliffe JS, Cattanach BM, Beechey CV, Armstrong D, Eichele G, Beaudet AL: Imprinted expression of the murine Angelman syndrome gene, Ube3a, in hippocampal and Purkinje neurons. Nat Genet 17: 75-78, 1997
-
(1997)
Nat Genet
, vol.17
, pp. 75-78
-
-
Albrecht, U.1
Sutcliffe, J.S.2
Cattanach, B.M.3
Beechey, C.V.4
Armstrong, D.5
Eichele, G.6
Beaudet, A.L.7
-
27
-
-
0035918146
-
ENaC degradation in A6 cells by the ubiquitin-proteasome proteolytic pathway
-
Malik B, Schlanger L, Al-Khalili O, Bao H-F, Yue G, Price SR, Mitch WE, Eaton DC: ENaC degradation in A6 cells by the ubiquitin-proteasome proteolytic pathway. J Biol Chem 276: 12903-12910, 2001
-
(2001)
J Biol Chem
, vol.276
, pp. 12903-12910
-
-
Malik, B.1
Schlanger, L.2
Al-Khalili, O.3
Bao, H.-F.4
Yue, G.5
Price, S.R.6
Mitch, W.E.7
Eaton, D.C.8
-
28
-
-
0034923626
-
Liddle's syndrome: A novel mouse Nedd4 isoform regulates the activity of the epithelial Na(+) channel
-
Kamynina E, Debonneville C, Hirt RP, Staub O: Liddle's syndrome: A novel mouse Nedd4 isoform regulates the activity of the epithelial Na(+) channel. Kidney Int 60: 466-471, 2001
-
(2001)
Kidney Int
, vol.60
, pp. 466-471
-
-
Kamynina, E.1
Debonneville, C.2
Hirt, R.P.3
Staub, O.4
-
29
-
-
11244351579
-
Function and regulation of cullin-RING ubiquitin ligases
-
Petroski MD, Deshaies RJ: Function and regulation of cullin-RING ubiquitin ligases. Nat Rev Mol Cell Biol 6: 9-20, 2005
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 9-20
-
-
Petroski, M.D.1
Deshaies, R.J.2
-
30
-
-
0033613222
-
RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination
-
Lorick KL, Jensen JP, Fang S, Ong AM, Hatakeyama S, Weissman AM: RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Proc Natl Acad Sci U S A 96: 11364-11369, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11364-11369
-
-
Lorick, K.L.1
Jensen, J.P.2
Fang, S.3
Ong, A.M.4
Hatakeyama, S.5
Weissman, A.M.6
-
31
-
-
20244389988
-
Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34
-
Seol JH, Feldman RM, Zachariae W, Shevchenko A, Correll CC, Lyapina S, Chi Y, Galova M, Claypool J, Sandmeyer S, Nasmyth K, Deshaies RJ, Shevchenko A, Deshaies RJ: Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev 13: 1614-1626, 1999
-
(1999)
Genes Dev
, vol.13
, pp. 1614-1626
-
-
Seol, J.H.1
Feldman, R.M.2
Zachariae, W.3
Shevchenko, A.4
Correll, C.C.5
Lyapina, S.6
Chi, Y.7
Galova, M.8
Claypool, J.9
Sandmeyer, S.10
Nasmyth, K.11
Deshaies, R.J.12
Shevchenko, A.13
Deshaies, R.J.14
-
32
-
-
0029760621
-
The MDM2 oncoprotein binds specifically to RNA through its RING finger domain
-
Elenbaas B, Dobbelstein M, Roth J, Shenk T, Levine AJ: The MDM2 oncoprotein binds specifically to RNA through its RING finger domain. Mol Med 2: 439-451, 1996
-
(1996)
Mol Med
, vol.2
, pp. 439-451
-
-
Elenbaas, B.1
Dobbelstein, M.2
Roth, J.3
Shenk, T.4
Levine, A.J.5
-
33
-
-
0034280526
-
Felix Hoppe-Seyler Lecture 2000: The ubiquitin system and the N-end rule pathway
-
32a. Varshavsky A, Turner G, Du F, Xie Y: Felix Hoppe-Seyler Lecture 2000: The ubiquitin system and the N-end rule pathway. Biol Chem 381: 779-789, 2000
-
(2000)
Biol Chem
, vol.381
, pp. 779-789
-
-
Varshavsky, A.1
Turner, G.2
Du, F.3
Xie, Y.4
-
34
-
-
0035912183
-
Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability
-
Rao H, Uhlmann F, Nasmyth K, Varshavsky A: Degradation of a cohesin subunit by the N-end rule pathway is essential for chromosome stability. Nature 410: 955-959, 2001
-
(2001)
Nature
, vol.410
, pp. 955-959
-
-
Rao, H.1
Uhlmann, F.2
Nasmyth, K.3
Varshavsky, A.4
-
35
-
-
27144557281
-
The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators
-
Hu RG, Sheng J, Qi X, Xu Z, Takahashi TT, Varshavsky A: The N-end rule pathway as a nitric oxide sensor controlling the levels of multiple regulators. Nature 437: 981-986, 2005
-
(2005)
Nature
, vol.437
, pp. 981-986
-
-
Hu, R.G.1
Sheng, J.2
Qi, X.3
Xu, Z.4
Takahashi, T.T.5
Varshavsky, A.6
-
36
-
-
0347285363
-
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
-
Lecker SH, Jagoe RT, Gomes M, Baracos V, Bailey JL, Price SR, Mitch WE, Goldberg AL: Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J 18: 39-51, 2004
-
(2004)
FASEB J
, vol.18
, pp. 39-51
-
-
Lecker, S.H.1
Jagoe, R.T.2
Gomes, M.3
Baracos, V.4
Bailey, J.L.5
Price, S.R.6
Mitch, W.E.7
Goldberg, A.L.8
-
37
-
-
0037098081
-
How oxygen makes its presence felt
-
Kaelin WG Jr: How oxygen makes its presence felt. Genes Dev 16: 1441-1445, 2002
-
(2002)
Genes Dev
, vol.16
, pp. 1441-1445
-
-
Kaelin Jr., W.G.1
-
39
-
-
9644270401
-
Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex
-
Li HH, Kedar V, Zhang C, McDonough H, Arya R, Wang DZ, Patterson C: Atrogin-1/muscle atrophy F-box inhibits calcineurin-dependent cardiac hypertrophy by participating in an SCF ubiquitin ligase complex. J Clin Invest 114: 1058-1071, 2004
-
(2004)
J Clin Invest
, vol.114
, pp. 1058-1071
-
-
Li, H.H.1
Kedar, V.2
Zhang, C.3
McDonough, H.4
Arya, R.5
Wang, D.Z.6
Patterson, C.7
-
40
-
-
0032867676
-
The 26S proteasome: A molecular machine designed for controlled proteolysis
-
Voges D, Zwickl P, Baumeister W: The 26S proteasome: A molecular machine designed for controlled proteolysis. Annu Rev Biochem 68: 1015-1068, 2000
-
(2000)
Annu Rev Biochem
, vol.68
, pp. 1015-1068
-
-
Voges, D.1
Zwickl, P.2
Baumeister, W.3
-
41
-
-
0034864799
-
Proteasome inhibitors: From research tools to drug candidates
-
Kisselev AF, Goldberg AL: Proteasome inhibitors: From research tools to drug candidates. Chem Biol 8: 739-758, 2001
-
(2001)
Chem Biol
, vol.8
, pp. 739-758
-
-
Kisselev, A.F.1
Goldberg, A.L.2
-
42
-
-
0033766480
-
A gated channel into the proteasome core particle
-
Groll M, Bajorek M, Kohler A, Moroder L, Rubin DM, Huber R, Glickman MH, Finley D: A gated channel into the proteasome core particle. Nat Struct Biol 7: 1062-1067, 2000
-
(2000)
Nat Struct Biol
, vol.7
, pp. 1062-1067
-
-
Groll, M.1
Bajorek, M.2
Kohler, A.3
Moroder, L.4
Rubin, D.M.5
Huber, R.6
Glickman, M.H.7
Finley, D.8
-
43
-
-
13244298289
-
Nobel committee tags ubiquitin for distinction
-
Goldberg AL: Nobel committee tags ubiquitin for distinction. Neuron 45: 339-344, 2005
-
(2005)
Neuron
, vol.45
, pp. 339-344
-
-
Goldberg, A.L.1
-
44
-
-
0037248908
-
ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation
-
Benaroudj N, Zwickl P, Seemuller E, Baumeister W, Goldberg AL: ATP hydrolysis by the proteasome regulatory complex PAN serves multiple functions in protein degradation. Mol Cell 11: 69-78, 2003
-
(2003)
Mol Cell
, vol.11
, pp. 69-78
-
-
Benaroudj, N.1
Zwickl, P.2
Seemuller, E.3
Baumeister, W.4
Goldberg, A.L.5
-
45
-
-
26844433577
-
Proteasome-associated proteins: Regulation of a proteolytic machine
-
Schmidt M, Hanna J, Elsasser S, Finley D: Proteasome-associated proteins: Regulation of a proteolytic machine. Biol Chem 386: 725-737, 2005
-
(2005)
Biol Chem
, vol.386
, pp. 725-737
-
-
Schmidt, M.1
Hanna, J.2
Elsasser, S.3
Finley, D.4
-
46
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
Goldberg AL: Protein degradation and protection against misfolded or damaged proteins. Nature 426: 895-899, 2003
-
(2003)
Nature
, vol.426
, pp. 895-899
-
-
Goldberg, A.L.1
-
47
-
-
28444452611
-
ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins
-
Smith DM, Kafri G, Cheng Y, Ng D, Walz T, Goldberg AL: ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins. Mol Cell 20: 687-698, 2005
-
(2005)
Mol Cell
, vol.20
, pp. 687-698
-
-
Smith, D.M.1
Kafri, G.2
Cheng, Y.3
Ng, D.4
Walz, T.5
Goldberg, A.L.6
-
48
-
-
0033525086
-
The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation
-
Kisselev AF, Akopian TN, Woo KM, Goldberg AL: The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation. J Biol Chem 274: 3363-3371, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 3363-3371
-
-
Kisselev, A.F.1
Akopian, T.N.2
Woo, K.M.3
Goldberg, A.L.4
-
49
-
-
1842785206
-
A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation
-
Reits E, Neijssen J, Herberts C, Benckhuijsen W, Janssen L, Drijfhout JW, Neefjes J: A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation. Immunity 20: 495-506, 2004
-
(2004)
Immunity
, vol.20
, pp. 495-506
-
-
Reits, E.1
Neijssen, J.2
Herberts, C.3
Benckhuijsen, W.4
Janssen, L.5
Drijfhout, J.W.6
Neefjes, J.7
-
50
-
-
8744237281
-
Pathway for degradation of peptides generated by proteasomes: A key role for thimet oligopeptidase and other metallopeptidases
-
Saric T, Graef CI, Goldberg AL: Pathway for degradation of peptides generated by proteasomes: A key role for thimet oligopeptidase and other metallopeptidases. J Biol Chem 279: 46723-46732, 2004
-
(2004)
J Biol Chem
, vol.279
, pp. 46723-46732
-
-
Saric, T.1
Graef, C.I.2
Goldberg, A.L.3
-
51
-
-
0027980321
-
The ubiquitin-proteasome pathway is required for processing the NF-kappaB1 precursor protein and the activation of NF-kappaB
-
Palombella VJ, Rando OJ, Goldberg AL, Maniatis T: The ubiquitin-proteasome pathway is required for processing the NF-kappaB1 precursor protein and the activation of NF-kappaB. Cell 78: 773-785, 1994
-
(1994)
Cell
, vol.78
, pp. 773-785
-
-
Palombella, V.J.1
Rando, O.J.2
Goldberg, A.L.3
Maniatis, T.4
-
52
-
-
1842766144
-
Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins
-
Venkatraman P, Wetzel R, Tanaka M, Nukina N, Goldberg AL: Eukaryotic proteasomes cannot digest polyglutamine sequences and release them during degradation of polyglutamine-containing proteins. Mol Cell 14: 95-104, 2004
-
(2004)
Mol Cell
, vol.14
, pp. 95-104
-
-
Venkatraman, P.1
Wetzel, R.2
Tanaka, M.3
Nukina, N.4
Goldberg, A.L.5
-
53
-
-
2342613652
-
The proteasome: A suitable antineoplastic target
-
Adams J: The proteasome: A suitable antineoplastic target. Nat Rev Cancer 4: 349-360, 2004
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 349-360
-
-
Adams, J.1
-
54
-
-
0036218697
-
Producing nature's gene-chips: The generation of peptides for display by MHC class I molecules
-
Shastri N, Schwab S, Serwold T: Producing nature's gene-chips: The generation of peptides for display by MHC class I molecules. Annu Rev Immunol 20: 463-493, 2002
-
(2002)
Annu Rev Immunol
, vol.20
, pp. 463-493
-
-
Shastri, N.1
Schwab, S.2
Serwold, T.3
-
55
-
-
0036017391
-
Protein degradation and the generation of MHC class I-presented peptides
-
Rock KL, York IA, Saric T, Goldberg AL: Protein degradation and the generation of MHC class I-presented peptides. Adv Immunol 80: 1-70, 2002
-
(2002)
Adv Immunol
, vol.80
, pp. 1-70
-
-
Rock, K.L.1
York, I.A.2
Saric, T.3
Goldberg, A.L.4
-
56
-
-
0034080319
-
Viral subversion of the immune system
-
Tortorella D, Gewurz BE, Furman MH, Schust DJ, Ploegh HL: Viral subversion of the immune system. Annu Rev Immunol 18: 861-926, 2000
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 861-926
-
-
Tortorella, D.1
Gewurz, B.E.2
Furman, M.H.3
Schust, D.J.4
Ploegh, H.L.5
-
57
-
-
3242807547
-
Post-proteasomal antigen processing for major histocompatibility complex class I presentation
-
Rock KL, York IA, Goldberg AL: Post-proteasomal antigen processing for major histocompatibility complex class I presentation. Nat Immunol 5: 670-677, 2004
-
(2004)
Nat Immunol
, vol.5
, pp. 670-677
-
-
Rock, K.L.1
York, I.A.2
Goldberg, A.L.3
-
58
-
-
0036902105
-
An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides
-
Saric T, Chang SC, Hattori A, York IA, Markant S, Rock KL, Tsujimoto M, Goldberg AL: An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides. Nat Immunol 3: 1169-1176, 2002
-
(2002)
Nat Immunol
, vol.3
, pp. 1169-1176
-
-
Saric, T.1
Chang, S.C.2
Hattori, A.3
York, I.A.4
Markant, S.5
Rock, K.L.6
Tsujimoto, M.7
Goldberg, A.L.8
-
59
-
-
0036884090
-
The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues
-
York IA, Chang SC, Saric T, Keys JA, Favreau JM, Goldberg AL, Rock KL: The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues. Nat Immunol 3: 1177-1184, 2002
-
(2002)
Nat Immunol
, vol.3
, pp. 1177-1184
-
-
York, I.A.1
Chang, S.C.2
Saric, T.3
Keys, J.A.4
Favreau, J.M.5
Goldberg, A.L.6
Rock, K.L.7
-
60
-
-
0028136465
-
Peptidase activities of proteasomes are differentially regulated by the MHC-encoded genes LMP2 and LMP7
-
Gaczynska M, Rock KL, Spies T, Goldberg AL: Peptidase activities of proteasomes are differentially regulated by the MHC-encoded genes LMP2 and LMP7. Proc Natl Acad Sci U S A 91: 9213-9217, 1994
-
(1994)
Proc Natl Acad Sci U S A
, vol.91
, pp. 9213-9217
-
-
Gaczynska, M.1
Rock, K.L.2
Spies, T.3
Goldberg, A.L.4
-
61
-
-
0037013955
-
Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes
-
Cascio P, Call M, Petre BM, Walz T, Goldberg AL: Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes. EMBO J 21: 2636-2645, 2002
-
(2002)
EMBO J
, vol.21
, pp. 2636-2645
-
-
Cascio, P.1
Call, M.2
Petre, B.M.3
Walz, T.4
Goldberg, A.L.5
-
62
-
-
0031891481
-
Factors predicting malnutrition in hemodialysis patients: A cross-sectional study
-
Qureshi AR, Alvestrand A, Danielsson A, Divino-Filho JC, Gutierrez A, Lindholm B, Bergstrom J: Factors predicting malnutrition in hemodialysis patients: A cross-sectional study. Kidney Int 53: 773-782, 1998
-
(1998)
Kidney Int
, vol.53
, pp. 773-782
-
-
Qureshi, A.R.1
Alvestrand, A.2
Danielsson, A.3
Divino-Filho, J.C.4
Gutierrez, A.5
Lindholm, B.6
Bergstrom, J.7
-
63
-
-
0035152603
-
National Kidney Foundation K/DOQI clinical practice guidelines for nutrition in chronic renal failure
-
Kopple JD: National Kidney Foundation K/DOQI clinical practice guidelines for nutrition in chronic renal failure. Am J Kidney Dis 37: S66-S70, 2001
-
(2001)
Am J Kidney Dis
, vol.37
-
-
Kopple, J.D.1
-
64
-
-
0036679425
-
Malnutrition: A frequent misdiagnosis for hemodialysis patients
-
Mitch WE: Malnutrition: A frequent misdiagnosis for hemodialysis patients. J Clin Invest 110: 437-439, 2002
-
(2002)
J Clin Invest
, vol.110
, pp. 437-439
-
-
Mitch, W.E.1
-
65
-
-
1642545155
-
Inflammation and reduced albumin synthesis associated with stable decline in serum albumin in hemodialysis patients
-
Kaysen GA, Dubin JA, Muller H-G, Rosales L, Levin NW, Mitch WE: Inflammation and reduced albumin synthesis associated with stable decline in serum albumin in hemodialysis patients. Kidney Int 65: 1408-1415, 2004
-
(2004)
Kidney Int
, vol.65
, pp. 1408-1415
-
-
Kaysen, G.A.1
Dubin, J.A.2
Muller, H.-G.3
Rosales, L.4
Levin, N.W.5
Mitch, W.E.6
-
66
-
-
0033919815
-
Protein metabolism in patients with chronic renal failure: Role of uremia and dialysis
-
Lim VS, Kopple JD: Protein metabolism in patients with chronic renal failure: Role of uremia and dialysis. Kidney Int 58: 1-10, 2000
-
(2000)
Kidney Int
, vol.58
, pp. 1-10
-
-
Lim, V.S.1
Kopple, J.D.2
-
67
-
-
0030009316
-
The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent, ubiquitin-proteasome pathway
-
Bailey JL, Wang X, England BK, Price SR, Ding X, Mitch WE: The acidosis of chronic renal failure activates muscle proteolysis in rats by augmenting transcription of genes encoding proteins of the ATP-dependent, ubiquitin-proteasome pathway. J Clin Invest 97: 1447-1453, 1996
-
(1996)
J Clin Invest
, vol.97
, pp. 1447-1453
-
-
Bailey, J.L.1
Wang, X.2
England, B.K.3
Price, S.R.4
Ding, X.5
Mitch, W.E.6
-
68
-
-
0036223212
-
Nutrition in CAPD: Serum bicarbonate and the ubiquitin-proteasome system in muscle
-
Pickering WP, Price SR, Bircher G, Marinovic AC, Mitch WE, Walls J: Nutrition in CAPD: Serum bicarbonate and the ubiquitin-proteasome system in muscle. Kidney Int 61: 1286-1292, 2002
-
(2002)
Kidney Int
, vol.61
, pp. 1286-1292
-
-
Pickering, W.P.1
Price, S.R.2
Bircher, G.3
Marinovic, A.C.4
Mitch, W.E.5
Walls, J.6
-
69
-
-
0029924205
-
Increased mRNA levels for components of the lysosomal, Ca++-activated and ATP-ubiquitin-dependent proteolytic pathways in skeletal muscle from head trauma patients
-
Mansoor O, Beaufrere Y, Boirie Y, Ralliere C, Taillandier D, Aurousseau E, Schoeffler P, Arnal M, Attaix D: Increased mRNA levels for components of the lysosomal, Ca++-activated and ATP-ubiquitin-dependent proteolytic pathways in skeletal muscle from head trauma patients. Proc Natl Acad Sci U S A 93: 2714-2718, 1996
-
(1996)
Proc Natl Acad Sci U S a
, vol.93
, pp. 2714-2718
-
-
Mansoor, O.1
Beaufrere, Y.2
Boirie, Y.3
Ralliere, C.4
Taillandier, D.5
Aurousseau, E.6
Schoeffler, P.7
Arnal, M.8
Attaix, D.9
-
70
-
-
0031018516
-
Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle
-
Tiao G, Hobler S, Wang JJ, Meyer TA, Luchette FA, Fischer JE, Hasseigren P-O: Sepsis is associated with increased mRNAs of the ubiquitin-proteasome proteolytic pathway in human skeletal muscle. J Clin Invest 99: 163-168, 1997
-
(1997)
J Clin Invest
, vol.99
, pp. 163-168
-
-
Tiao, G.1
Hobler, S.2
Wang, J.J.3
Meyer, T.A.4
Luchette, F.A.5
Fischer, J.E.6
Hasseigren, P.-O.7
-
71
-
-
0032863110
-
The expression of genes in the ubiquitin-proteasome proteolytic pathway is increased in skeletal muscle from patients with cancer
-
Williams AB, Sun X, Fischer JE, Hasseigren P-O: The expression of genes in the ubiquitin-proteasome proteolytic pathway is increased in skeletal muscle from patients with cancer. Surgery 126: 744-749, 1999
-
(1999)
Surgery
, vol.126
, pp. 744-749
-
-
Williams, A.B.1
Sun, X.2
Fischer, J.E.3
Hasseigren, P.-O.4
-
72
-
-
0029861468
-
Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome pathway by a mechanism including gene transcription
-
Price SR, Bailey JL, Wang X, Jurkovitz C, England BK, Ding X, Phillips LS, Mitch WE: Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome pathway by a mechanism including gene transcription. J Clin Invest 98: 1703-1708, 1996
-
(1996)
J Clin Invest
, vol.98
, pp. 1703-1708
-
-
Price, S.R.1
Bailey, J.L.2
Wang, X.3
Jurkovitz, C.4
England, B.K.5
Ding, X.6
Phillips, L.S.7
Mitch, W.E.8
-
73
-
-
0033060435
-
Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting
-
Mitch WE, Bailey JL, Wang X, Jurkovitz C, Newby D, Price SR: Evaluation of signals activating ubiquitin-proteasome proteolysis in a model of muscle wasting. Am J Physiol 276: C1132-C1138, 1999
-
(1999)
Am J Physiol
, vol.276
-
-
Mitch, W.E.1
Bailey, J.L.2
Wang, X.3
Jurkovitz, C.4
Newby, D.5
Price, S.R.6
-
74
-
-
1842339868
-
Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles
-
Tawa NE, Odessey R, Goldberg AL: Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles. J Clin Invest 100: 197-203, 1997
-
(1997)
J Clin Invest
, vol.100
, pp. 197-203
-
-
Tawa, N.E.1
Odessey, R.2
Goldberg, A.L.3
-
75
-
-
0035941020
-
Identification of ubiquitin ligases required for skeletal muscle atrophy
-
Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clark BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuel DM, DeChiara TM, Stitt TN, Yancopoulos GD, Glass DJ: Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294: 1704-1708, 2001
-
(2001)
Science
, vol.294
, pp. 1704-1708
-
-
Bodine, S.C.1
Latres, E.2
Baumhueter, S.3
Lai, V.K.4
Nunez, L.5
Clark, B.A.6
Poueymirou, W.T.7
Panaro, F.J.8
Na, E.9
Dharmarajan, K.10
Pan, Z.Q.11
Valenzuel, D.M.12
Dechiara, T.M.13
Stitt, T.N.14
Yancopoulos, G.D.15
Glass, D.J.16
-
76
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
Sandri M, Sandri C, Gilbert A, Skuck C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL: Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117: 399-412, 2004
-
(2004)
Cell
, vol.117
, pp. 399-412
-
-
Sandri, M.1
Sandri, C.2
Gilbert, A.3
Skuck, C.4
Calabria, E.5
Picard, A.6
Walsh, K.7
Schiaffino, S.8
Lecker, S.H.9
Goldberg, A.L.10
-
77
-
-
2042425906
-
The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors
-
Stitt TN, Drujan D, Clarke BA, Panaro F, Timofeyva Y, Klinenber JR, Gonzalez M, Yancopoulos GD, Glass DJ: The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Mol Cell 14: 395-403, 2004
-
(2004)
Mol Cell
, vol.14
, pp. 395-403
-
-
Stitt, T.N.1
Drujan, D.2
Clarke, B.A.3
Panaro, F.4
Timofeyva, Y.5
Klinenber, J.R.6
Gonzalez, M.7
Yancopoulos, G.D.8
Glass, D.J.9
-
78
-
-
4544293878
-
IGF-1 stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1
-
Sacheck JM, Ohtsuka A, McLary SC, Goldberg AL: IGF-1 stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1. Am J Physiol 287: E591-E601, 2004
-
(2004)
Am J Physiol
, vol.287
-
-
Sacheck, J.M.1
Ohtsuka, A.2
McLary, S.C.3
Goldberg, A.L.4
-
79
-
-
13244264946
-
Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase
-
Tintignac LA, Lagirand J, Batonnet S, Sirri V, Leibovitch MP, Leibovitch SA: Degradation of MyoD mediated by the SCF (MAFbx) ubiquitin ligase. J Biol Chem 280: 2847-2856, 2005
-
(2005)
J Biol Chem
, vol.280
, pp. 2847-2856
-
-
Tintignac, L.A.1
Lagirand, J.2
Batonnet, S.3
Sirri, V.4
Leibovitch, M.P.5
Leibovitch, S.A.6
-
80
-
-
0035818491
-
Calcineurin controls nerve activity-dependent specification of slow skeletal muscle fibers but not muscle growth
-
Serrano AL, Murgia M, Pallafacchina G, Calabria E, Coniglio P, Lomo T, Schiaffino S: Calcineurin controls nerve activity-dependent specification of slow skeletal muscle fibers but not muscle growth. Proc Natl Acad Sci U S A 98: 13108-13113, 2001
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 13108-13113
-
-
Serrano, A.L.1
Murgia, M.2
Pallafacchina, G.3
Calabria, E.4
Coniglio, P.5
Lomo, T.6
Schiaffino, S.7
-
81
-
-
0036544533
-
Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1
-
McElhinny AS, Kakinuma K, Sorimachi H, Labeit S, Gregorio CC: Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1. J Cell Biol 157: 125-136, 2002
-
(2002)
J Cell Biol
, vol.157
, pp. 125-136
-
-
McElhinny, A.S.1
Kakinuma, K.2
Sorimachi, H.3
Labeit, S.4
Gregorio, C.C.5
-
82
-
-
11144237310
-
Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin 1
-
Kedar V, McDonough H, Arya R, Li HH, Rockman HA, Patterson C: Muscle-specific RING finger 1 is a bona fide ubiquitin ligase that degrades cardiac troponin 1. Proc Natl Acad Sci U S A 101: 18135-18140, 2004
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 18135-18140
-
-
Kedar, V.1
McDonough, H.2
Arya, R.3
Li, H.H.4
Rockman, H.A.5
Patterson, C.6
-
83
-
-
2542496898
-
Regulation of muscle protein degradation: Coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase
-
Lee SW, Dai G, Hu Z, Wang X, Du J, Mitch WE: Regulation of muscle protein degradation: Coordinated control of apoptotic and ubiquitin-proteasome systems by phosphatidylinositol 3 kinase. J Am Soc Nephrol 15: 1537-1545, 2004
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1537-1545
-
-
Lee, S.W.1
Dai, G.2
Hu, Z.3
Wang, X.4
Du, J.5
Mitch, W.E.6
-
84
-
-
5444262078
-
IKKbeta/NF-kappaB activation causes severe muscle wasting in mice
-
Cai D, Frantz JD, Tawa NE, Melendez PA, Oh BC, Lidov HG, Hasselgren PO, Frontera WR, Lee J, Glass DJ, Shoelson SE: IKKbeta/NF-kappaB activation causes severe muscle wasting in mice. Cell 119: 285-298, 2004
-
(2004)
Cell
, vol.119
, pp. 285-298
-
-
Cai, D.1
Frantz, J.D.2
Tawa, N.E.3
Melendez, P.A.4
Oh, B.C.5
Lidov, H.G.6
Hasselgren, P.O.7
Frontera, W.R.8
Lee, J.9
Glass, D.J.10
Shoelson, S.E.11
-
85
-
-
8544237014
-
Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia
-
Kwak KS, Zhou X, Solomon V, Baracos VE, Davis J, Bannon AW, Boyle WJ, Lacey DL, Han HQ: Regulation of protein catabolism by muscle-specific and cytokine-inducible ubiquitin ligase E3alpha-II during cancer cachexia. Cancer Res 64: 8193-8198, 2004
-
(2004)
Cancer Res
, vol.64
, pp. 8193-8198
-
-
Kwak, K.S.1
Zhou, X.2
Solomon, V.3
Baracos, V.E.4
Davis, J.5
Bannon, A.W.6
Boyle, W.J.7
Lacey, D.L.8
Han, H.Q.9
-
86
-
-
0029956781
-
Importance of the ATP-ubiquitin-proteasome pathway in degradation of soluble and myofibrillar proteins in rabbit muscle extracts
-
Solomon V, Goldberg AL: Importance of the ATP-ubiquitin-proteasome pathway in degradation of soluble and myofibrillar proteins in rabbit muscle extracts. J Biol Chem 271: 26690-26697, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 26690-26697
-
-
Solomon, V.1
Goldberg, A.L.2
-
87
-
-
0029861143
-
The N-end rule: Functions, mysteries, uses
-
Varshavsky A: The N-end rule: Functions, mysteries, uses. Proc Natl Acad Sci U S A 93: 12142-12149, 1996
-
(1996)
Proc Natl Acad Sci U S a
, vol.93
, pp. 12142-12149
-
-
Varshavsky, A.1
-
88
-
-
0032514735
-
Rates of ubiquitin conjugation increase when muscles atrophy, largely through activation of the N-end rule pathway
-
Solomon V, Baracos V, Sarraf P, Goldberg AL: Rates of ubiquitin conjugation increase when muscles atrophy, largely through activation of the N-end rule pathway. Proc Natl Acad Sci U S A 95: 12602-12607, 1998
-
(1998)
Proc Natl Acad Sci U S a
, vol.95
, pp. 12602-12607
-
-
Solomon, V.1
Baracos, V.2
Sarraf, P.3
Goldberg, A.L.4
-
89
-
-
0032751546
-
Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats
-
Lecker SH, Solomon V, Price SR, Kwon YT, Mitch WE, Goldberg AL: Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats. J Clin Invest 104: 1411-1420, 1999
-
(1999)
J Clin Invest
, vol.104
, pp. 1411-1420
-
-
Lecker, S.H.1
Solomon, V.2
Price, S.R.3
Kwon, Y.T.4
Mitch, W.E.5
Goldberg, A.L.6
-
90
-
-
0030061922
-
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance
-
Hotamisligil GS, Peraldi P, Budavari A, Ellis R, White MF, Spielgelman BM: IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance. Science 271: 665-668, 1996
-
(1996)
Science
, vol.271
, pp. 665-668
-
-
Hotamisligil, G.S.1
Peraldi, P.2
Budavari, A.3
Ellis, R.4
White, M.F.5
Spielgelman, B.M.6
-
91
-
-
0018462128
-
Glucose intolerance following chronic metabolic acidosis in man
-
DeFronzo RA, Beckles AD: Glucose intolerance following chronic metabolic acidosis in man. Am J Physiol 236: E328-E334, 1979
-
(1979)
Am J Physiol
, vol.236
-
-
Defronzo, R.A.1
Beckles, A.D.2
-
92
-
-
0031835451
-
Immunologic function and survival in hemodialysis patients
-
Kimmel PL, Phillips TM, Simmens SJ, Peterson RA, Weihs KL, Alleyne S, Cruz I, Yanovski JA, Veis JH: Immunologic function and survival in hemodialysis patients. Kidney Int 54: 236-244, 1998
-
(1998)
Kidney Int
, vol.54
, pp. 236-244
-
-
Kimmel, P.L.1
Phillips, T.M.2
Simmens, S.J.3
Peterson, R.A.4
Weihs, K.L.5
Alleyne, S.6
Cruz, I.7
Yanovski, J.A.8
Veis, J.H.9
-
93
-
-
85047693596
-
Activation of caspase 3 is an initial step triggering muscle proteolysis in catabolic conditions
-
Du J, Wang X, Meireles CL, Bailey JL, Debigare R, Zheng B, Price SR, Mitch WE: Activation of caspase 3 is an initial step triggering muscle proteolysis in catabolic conditions. J Clin Invest 113: 115-123, 2004
-
(2004)
J Clin Invest
, vol.113
, pp. 115-123
-
-
Du, J.1
Wang, X.2
Meireles, C.L.3
Bailey, J.L.4
Debigare, R.5
Zheng, B.6
Price, S.R.7
Mitch, W.E.8
-
94
-
-
14844336534
-
Muscle-specific expression of insulin-like growth factor-1 blocks angiotensin II-induced skeletal muscle wasting
-
Song Y-H, Li Y, Du J, Mitch WE, Rosenthal N, Delafontaine P: Muscle-specific expression of insulin-like growth factor-1 blocks angiotensin II-induced skeletal muscle wasting. J Clin Invest 115: 451-458, 2005
-
(2005)
J Clin Invest
, vol.115
, pp. 451-458
-
-
Song, Y.-H.1
Li, Y.2
Du, J.3
Mitch, W.E.4
Rosenthal, N.5
Delafontaine, P.6
-
95
-
-
85190699231
-
Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions, including kidney failure
-
Workeneh BT, Rondon-Berrios H, Ayehu G, Hu Z, Ferrando A, Wang H, Kopple JD, Du J, Mitch WE: Development of a diagnostic method for detecting increased muscle protein degradation in patients with catabolic conditions, including kidney failure [Abstract]. J Am Soc Nephrol 16: 713A, 2005
-
(2005)
J Am Soc Nephrol
, vol.16
-
-
Workeneh, B.T.1
Rondon-Berrios, H.2
Ayehu, G.3
Hu, Z.4
Ferrando, A.5
Wang, H.6
Kopple, J.D.7
Du, J.8
Mitch, W.E.9
-
96
-
-
13844274895
-
Sepsis stimulates calpain activity in skeletal muscle by decreasing calpastatin activity but does not activate caspase-3
-
Wei W, Fareed MU, Evenson A, Menconi MJ, Yang H, Petkova V, Hasselgren PO: Sepsis stimulates calpain activity in skeletal muscle by decreasing calpastatin activity but does not activate caspase-3. Am J Physiol Regul Integr Comp Physiol 288: R580-R590, 2005
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.288
-
-
Wei, W.1
Fareed, M.U.2
Evenson, A.3
Menconi, M.J.4
Yang, H.5
Petkova, V.6
Hasselgren, P.O.7
-
97
-
-
0037115363
-
Expression of a calpastatin transgene slows muscle wasting and obviates changes in myosin isoform expression during murine muscle disuse
-
Tidball JG, Spencer MJ: Expression of a calpastatin transgene slows muscle wasting and obviates changes in myosin isoform expression during murine muscle disuse. J Physiol 545: 819-828, 2002
-
(2002)
J Physiol
, vol.545
, pp. 819-828
-
-
Tidball, J.G.1
Spencer, M.J.2
-
98
-
-
0032952901
-
Strong association between malnutrition, inflammation and atherosclerosis in chronic kidney failure
-
Stenvinkel P, Heimburger O, Paultre F, Diczfalusy U, Wang T, Berglund L, Jogestrand T: Strong association between malnutrition, inflammation and atherosclerosis in chronic kidney failure. Kidney Int 55: 1899-1911, 1999
-
(1999)
Kidney Int
, vol.55
, pp. 1899-1911
-
-
Stenvinkel, P.1
Heimburger, O.2
Paultre, F.3
Diczfalusy, U.4
Wang, T.5
Berglund, L.6
Jogestrand, T.7
-
99
-
-
0028212481
-
Metabolic acidosis stimulates muscle protein degradation by activating the ATP-dependent pathway involving ubiquitin and proteasomes. J
-
Mitch WE, Medina R, Greiber S, May RC, England BK, Price SR, Bailey JL, Goldberg AL: Metabolic acidosis stimulates muscle protein degradation by activating the ATP-dependent pathway involving ubiquitin and proteasomes. J Clin Invest 93: 2127-2133, 1994
-
(1994)
Clin Invest
, vol.93
, pp. 2127-2133
-
-
Mitch, W.E.1
Medina, R.2
Greiber, S.3
May, R.C.4
England, B.K.5
Price, S.R.6
Bailey, J.L.7
Goldberg, A.L.8
-
100
-
-
0029945963
-
Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo
-
May RC, Bailey JL, Mitch WE, Masud T, England BK: Glucocorticoids and acidosis stimulate protein and amino acid catabolism in vivo. Kidney Int 49: 679-683, 1996
-
(1996)
Kidney Int
, vol.49
, pp. 679-683
-
-
May, R.C.1
Bailey, J.L.2
Mitch, W.E.3
Masud, T.4
England, B.K.5
-
101
-
-
85190703032
-
Diabetes in db/db mice causes muscle atrophy via the ubiquitin-proteasome system and is reversed by rosiglitazone administration
-
Wang XH, Hu JP, Hu Z, Du J, Mitch WE: Diabetes in db/db mice causes muscle atrophy via the ubiquitin-proteasome system and is reversed by rosiglitazone administration [Abstract]. J Am Soc Nephrol 16: 632A, 2005
-
(2005)
J Am Soc Nephrol
, vol.16
-
-
Wang, X.H.1
Hu, J.P.2
Hu, Z.3
Du, J.4
Mitch, W.E.5
-
102
-
-
0027489828
-
Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats
-
Saad MJA, Folli F, Kahn JA, Kahn CR: Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats. J Clin Invest 92: 2065-2072, 1993
-
(1993)
J Clin Invest
, vol.92
, pp. 2065-2072
-
-
Mja, S.1
Folli, F.2
Kahn, J.A.3
Kahn, C.R.4
-
103
-
-
14644427890
-
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB
-
Cai D, Yuan M, Frantz DF, Melendez PA, Hansen L, Lee J, Shoelson SE: Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 11: 183-190, 2005
-
(2005)
Nat Med
, vol.11
, pp. 183-190
-
-
Cai, D.1
Yuan, M.2
Frantz, D.F.3
Melendez, P.A.4
Hansen, L.5
Lee, J.6
Shoelson, S.E.7
-
104
-
-
33646354403
-
Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: Implications for muscle atrophy
-
Bailey JL, Price SR, Xhang B, Mitch WE: Chronic kidney disease causes defects in signaling through the insulin receptor substrate/phosphatidylinositol 3-kinase/Akt pathway: Implications for muscle atrophy. J Am Soc Nephrol 17: 1388-1394, 2006
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1388-1394
-
-
Bailey, J.L.1
Price, S.R.2
Xhang, B.3
Mitch, W.E.4
-
105
-
-
0035736260
-
Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
-
Bodine SC, Stitt TN, Gonzalez M, Kline WO, Stover GL, Bauerlein R, Zlotchenko E, Scrimgeour A, Lawrence JC, Glass DJ, Yancopoulos GD: Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat Cell Biol 3: 1014-1019, 2001
-
(2001)
Nat Cell Biol
, vol.3
, pp. 1014-1019
-
-
Bodine, S.C.1
Stitt, T.N.2
Gonzalez, M.3
Kline, W.O.4
Stover, G.L.5
Bauerlein, R.6
Zlotchenko, E.7
Scrimgeour, A.8
Lawrence, J.C.9
Glass, D.J.10
Yancopoulos, G.D.11
-
106
-
-
11144317940
-
Disruption of either the NFKB1 or the Bcl3 gene inhibits skeletal muscle atrophy
-
Hunter RB, Kandarian SC: Disruption of either the NFKB1 or the Bcl3 gene inhibits skeletal muscle atrophy. J Clin Invest 114: 1504-1511, 2004
-
(2004)
J Clin Invest
, vol.114
, pp. 1504-1511
-
-
Hunter, R.B.1
Kandarian, S.C.2
-
108
-
-
0028881695
-
Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats: Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging
-
Dardevet DD, Sornet C, Taillandier D, Savary I, Attaix D, Grizard J: Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats: Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging. J Clin Invest 96: 2113-2119, 1995
-
(1995)
J Clin Invest
, vol.96
, pp. 2113-2119
-
-
Dardevet, D.D.1
Sornet, C.2
Taillandier, D.3
Savary, I.4
Attaix, D.5
Grizard, J.6
-
109
-
-
0027460118
-
Glucocorticoids activate the ATP-ubiquitin-dependent proteolytic system in skeletal muscle during fasting
-
Wing SS, Goldberg AL: Glucocorticoids activate the ATP-ubiquitin- dependent proteolytic system in skeletal muscle during fasting. Am J Physiol 264: E668-E676, 1993
-
(1993)
Am J Physiol
, vol.264
-
-
Wing, S.S.1
Goldberg, A.L.2
-
110
-
-
0027972943
-
Acidosis and glucocorticoids concomitantly increase ubiquitin and proteasome subunit mRNAs in rat muscle
-
Price SR, England BK, Bailey JL, Van Vreede K, Mitch WE: Acidosis and glucocorticoids concomitantly increase ubiquitin and proteasome subunit mRNAs in rat muscle. Am J Physiol 267: C955-C960, 1994
-
(1994)
Am J Physiol
, vol.267
-
-
Price, S.R.1
England, B.K.2
Bailey, J.L.3
Van Vreede, K.4
Mitch, W.E.5
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