ROS, mitochondria and the regulation of autophagy

Trends in Cell Biology

Volumn 17, Issue 9, 2007, Pages 422-427

  Scherz Shouval, Ruth ^a   Elazar, Zvulun ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

REACTIVE OXYGEN METABOLITE;

ARTICLE; AUTOPHAGY; BIOGENESIS; CELL DEATH; CELL ORGANELLE; CELL SURVIVAL; EUKARYOTIC CELL; MACROMOLECULE; MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PHAGOSOME; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

AUTOPHAGY; CELL DEATH; CELL SURVIVAL; HYDROGEN PEROXIDE; MITOCHONDRIA; OXIDANTS; OXIDATIVE STRESS; PHAGOSOMES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EUKARYOTA;

EID: 34848920863     PISSN: 09628924     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tcb.2007.07.009     Document Type: Article

References (60)

1. Grune T., et al. Selective degradation of oxidatively modified protein substrates by the proteasome. Biochem. Biophys. Res. Commun. 305 (2003) 709-718
2. Kiffin R., et al. Oxidative stress and autophagy. Antioxid. Redox Signal. 8 (2006) 152-162
3. Terman A., and Brunk U.T. Lipofuscin: mechanisms of formation and increase with age. APMIS 106 (1998) 265-276
4. Donati A., et al. Age-related changes in the autophagic proteolysis of rat isolated liver cells: effects of antiaging dietary restrictions. J. Gerontol. A Biol. Sci. Med. Sci. 56 (2001) B375-B383
5. Rubinsztein D.C. The roles of intracellular protein-degradation pathways in neurodegeneration. Nature 443 (2006) 780-786
6. Cuervo A.M., and Dice J.F. Age-related decline in chaperone-mediated autophagy. J. Biol. Chem. 275 (2000) 31505-31513
7. Cataldo A.M., et al. Properties of the endosomal-lysosomal system in the human central nervous system: disturbances mark most neurons in populations at risk to degenerate in Alzheimer's disease. J. Neurosci. 16 (1996) 186-199
8. Sooparb S., et al. Suppression of chaperone-mediated autophagy in the renal cortex during acute diabetes mellitus. Kidney Int. 65 (2004) 2135-2144
9. Farre J.C., and Subramani S. Peroxisome turnover by micropexophagy: an autophagy-related process. Trends Cell Biol. 14 (2004) 515-523
10. Yorimitsu T., and Klionsky D.J. Eating the endoplasmic reticulum: quality control by autophagy. Trends Cell Biol. 17 (2007) 279-285
11. Kruse K.B., et al. Characterization of an ERAD gene as VPS30/ATG6 reveals two alternative and functionally distinct protein quality control pathways: one for soluble Z variant of human alpha-1 proteinase inhibitor (A1PiZ) and another for aggregates of A1PiZ. Mol. Biol. Cell 17 (2006) 203-212
12. Bernales S., et al. Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response. PLoS Biol. 4 (2006) e423
13. Hamasaki M., et al. Starvation triggers the delivery of the endoplasmic reticulum to the vacuole via autophagy in yeast. Traffic 6 (2005) 56-65
14. Lemasters J.J. Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging. Rejuvenation Res. 8 (2005) 3-5
15. Massey A.C., et al. Chaperone-mediated autophagy in aging and disease. Curr. Top. Dev. Biol. 73 (2006) 205-235
16. Finn P.F., and Dice J.F. Ketone bodies stimulate chaperone-mediated autophagy. J. Biol. Chem. 280 (2005) 25864-25870
17. Kiffin R., et al. Activation of chaperone-mediated autophagy during oxidative stress. Mol. Biol. Cell 15 (2004) 4829-4840
18. Kaushik S., and Cuervo A.M. Autophagy as a cell-repair mechanism: activation of chaperone-mediated autophagy during oxidative stress. Mol. Aspects Med. 27 (2006) 444-454
19. Xiong Y., et al. Degradation of oxidized proteins by autophagy during oxidative stress in Arabidopsis. Plant Physiol. 143 (2007) 291-299
20. Gozuacik D., and Kimchi A. Autophagy and cell death. Curr. Top. Dev. Biol. 78 (2007) 217-245
21. Codogno P., and Meijer A.J. Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ. 12 Suppl. 2 (2005) 1509-1518
22. Shintani T., and Klionsky D.J. Autophagy in health and disease: a double-edged sword. Science 306 (2004) 990-995
23. Gomez-Santos C., et al. Dopamine induces autophagic cell death and alpha-synuclein increase in human neuroblastoma SH-SY5Y cells. J. Neurosci. Res. 73 (2003) 341-350
24. Scherz-Shouval R., et al. Oxidation as a post-translational modification that regulates autophagy. Autophagy 3 (2007) 371-373
25. Finkel T. Oxidant signals and oxidative stress. Curr. Opin. Cell Biol. 15 (2003) 247-254
26. Kirkland R.A., et al. Loss of cardiolipin and mitochondria during programmed neuronal death: evidence of a role for lipid peroxidation and autophagy. Neuroscience 115 (2002) 587-602
27. Xue L., et al. Autophagy is activated by apoptotic signalling in sympathetic neurons: an alternative mechanism of death execution. Mol. Cell. Neurosci. 14 (1999) 180-198
28. Djavaheri-Mergny M., et al. NF-κB activation represses tumor necrosis factor-α-induced autophagy. J. Biol. Chem. 281 (2006) 30373-30382
29. Liang X.H., et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1. Nature 402 (1999) 672-676
30. Ichimura Y., et al. A ubiquitin-like system mediates protein lipidation. Nature 408 (2000) 488-492
31. Xu Y., et al. Autophagy contributes to caspase-independent macrophage cell death. J. Biol. Chem. 281 (2006) 19179-19187
32. Heitman J., et al. Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 253 (1991) 905-909
33. Kissova I., et al. Lipid oxidation and autophagy in yeast. Free Radic. Biol. Med. 41 (2006) 1655-1661
34. Reef S., et al. A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death. Mol. Cell 22 (2006) 463-475
35. Yu L., et al. Autophagic programmed cell death by selective catalase degradation. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 4952-4957
36. Scherz-Shouval R., et al. Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4. EMBO J. 26 (2007) 1749-1760
37. Kirisako T., et al. The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway. J. Cell Biol. 151 (2000) 263-276
38. Suh Y.A., et al. Cell transformation by the superoxide-generating oxidase Mox1. Nature 401 (1999) 79-82
39. Edens W.A., et al. Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox. J. Cell Biol. 154 (2001) 879-891
40. Lambeth J.D. NOX enzymes and the biology of reactive oxygen. Nat. Rev. Immunol. 4 (2004) 181-189
41. Bedard K., and Krause K.H. The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 87 (2007) 245-313
42. Adam-Vizi V., and Chinopoulos C. Bioenergetics and the formation of mitochondrial reactive oxygen species. Trends Pharmacol. Sci. 27 (2006) 639-645
43. Kern J.C., and Kehrer J.P. Free radicals and apoptosis: relationships with glutathione, thioredoxin, and the BCL family of proteins. Front. Biosci. 10 (2005) 1727-1738
44. Dorval J., and Hontela A. Role of glutathione redox cycle and catalase in defense against oxidative stress induced by endosulfan in adrenocortical cells of rainbow trout (Oncorhynchus mykiss). Toxicol. Appl. Pharmacol. 192 (2003) 191-200
45. Fleury C., et al. Mitochondrial reactive oxygen species in cell death signaling. Biochimie 84 (2002) 131-141
46. Lancaster Jr. J.R., et al. Inhibition of target cell mitochondrial electron transfer by tumor necrosis factor. FEBS Lett. 248 (1989) 169-174
47. Reggiori F., et al. Atg9 cycles between mitochondria and the pre-autophagosomal structure in yeasts. Autophagy 1 (2005) 101-109
48. Yamada T., et al. Endothelial nitric-oxide synthase antisense (NOS3AS) gene encodes an autophagy-related protein (APG9-like2) highly expressed in trophoblast. J. Biol. Chem. 280 (2005) 18283-18290
49. Young A.R., et al. Starvation and ULK1-dependent cycling of mammalian Atg9 between the TGN and endosomes. J. Cell Sci. 119 (2006) 3888-3900
50. Suzuki K., et al. The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation. EMBO J. 20 (2001) 5971-5981
51. Percival M.D., et al. Inhibition of cathepsin K by nitric oxide donors: evidence for the formation of mixed disulfides and a sulfenic acid. Biochemistry 38 (1999) 13574-13583
52. Kissova I., et al. Uth1p is involved in the autophagic degradation of mitochondria. J. Biol. Chem. 279 (2004) 39068-39074
53. Lemasters J.J., et al. The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochim. Biophys. Acta 1366 (1998) 177-196
54. Tal R., et al. Aup1p, a yeast mitochondrial protein phosphatase homolog, is required for efficient stationary phase mitophagy and cell survival. J. Biol. Chem. 282 (2007) 5617-5624
55. Priault M., et al. Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast. Cell Death Differ. 12 (2005) 1613-1621
56. Bjelland S., and Seeberg E. Mutagenicity, toxicity and repair of DNA base damage induced by oxidation. Mutat. Res. 531 (2003) 37-80
57. Zorov D.B., et al. Reactive oxygen species (ROS)-induced ROS release: a new phenomenon accompanying induction of the mitochondrial permeability transition in cardiac myocytes. J. Exp. Med. 192 (2000) 1001-1014
58. Ohsumi Y. Molecular dissection of autophagy: two ubiquitin-like systems. Nat. Rev. Mol. Cell Biol. 2 (2001) 211-216
59. Klionsky D.J., and Emr S.D. Autophagy as a regulated pathway of cellular degradation. Science 290 (2000) 1717-1721
60. Dileepan K.N., and Kennedy J. Complete inhibition of dihydro-orotate oxidation and superoxide production by 1,1,1-trifluoro-3-thenoylacetone in rat liver mitochondria. Biochem. J. 225 (1985) 189-194