A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS

Nature Cell Biology

Volumn 15, Issue 10, 2013, Pages 1186-1196

  Zhang, Jiangwei ^a   Kim, Jinhee ^b   Alexander, Angela ^a   Cai, Shengli ^a   Tripathi, Durga Nand ^a   Dere, Ruhee ^a   Tee, Andrew R ^c   Tait Mulder, Jacqueline ^d   Di Nardo, Alessia ^e   Han, Juliette M ^e   Kwiatkowski, Erica ^e   Dunlop, Elaine A ^c   Dodd, Kayleigh M ^c   Folkerth, Rebecca D ^f   Faust, Phyllis L ^g   Kastan, Michael B ^d   Sahin, Mustafa ^e   Walker, Cheryl Lyn ^a  

^a TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^b Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

^f BOSTON CHILDREN S HOSPITAL   (United States)

^g NewYork Presbyterian Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HAMARTIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PEROXIN; PEROXIN 19; PEROXIN 5; REACTIVE OXYGEN METABOLITE; RHEB PROTEIN; TUBERIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; AUTOPHAGY; CELL POLARITY; CELL STRAIN HEK293; CELL STRAIN HEPG2; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSOL; GENE REPRESSION; HELA CELL; HUMAN; HUMAN CELL; MOUSE; NERVE FIBER; NONHUMAN; PEROXISOME; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION; TUBEROUS SCLEROSIS COMPLEX 2 GENE;

ANIMALS; AUTOPHAGY; CELL LINE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEK293 CELLS; HUMANS; MCF-7 CELLS; MEMBRANE PROTEINS; MICE; MULTIPROTEIN COMPLEXES; PEROXISOMES; PROTEIN BINDING; RATS; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 84885105969     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb2822     Document Type: Article

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