The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM +/-/ApoE -/- mice

Free Radical Biology and Medicine

Volumn 52, Issue 5, 2012, Pages 841-849

  Mercer, John R ^a   Yu, Emma ^a   Figg, Nichola ^a   Cheng, Kian Kai ^a   Prime, Tracy A ^b   Griffin, Julian L ^a,c   Masoodi, Mojgan ^c   Vidal Puig, Antonio ^a   Murphy, Michael P ^b   Bennett, Martin R ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c MRC HUMAN NUTRITION RESEARCH   (United Kingdom)

Author keywords

Atherosclerosis; Metabolic syndrome; Mitochondria; MitoQ

Indexed keywords

8 HYDROXYGUANINE; ANTIOXIDANT; ANTIOXIDANT MITOQ; APOLIPOPROTEIN E; ATM PROTEIN; DNA; HYDROGEN PEROXIDE; LIPID; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROTIC PLAQUE; BODY COMPOSITION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DAMAGE; ENERGY EXPENDITURE; FATTY LIVER; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; HYPERTRIGLYCERIDEMIA; MACROPHAGE; METABOLIC SYNDROME X; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PHYSICAL ACTIVITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ADIPOSITY; ANIMALS; ANTIOXIDANTS; APOLIPOPROTEINS E; ATHEROSCLEROSIS; BLOOD GLUCOSE; CELL CYCLE PROTEINS; CELLS, CULTURED; DIET, HIGH-FAT; DNA-BINDING PROTEINS; ENERGY METABOLISM; FEMALE; LIPID METABOLISM; LIPIDS; LIVER; MALE; METABOLIC SYNDROME X; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; ORGAN SIZE; ORGANOPHOSPHORUS COMPOUNDS; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PLAQUE, ATHEROSCLEROTIC; PROTEIN CARBONYLATION; PROTEIN-SERINE-THREONINE KINASES; REACTIVE OXYGEN SPECIES; TUMOR SUPPRESSOR PROTEINS; UBIQUINONE;

ATAXIA TELANGIECTASIA; MUS;

EID: 84856752588     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.11.026     Document Type: Article

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