Mitochondrial oxidative stress causes mitochondrial fragmentation via differential modulation of mitochondrial fission-fusion proteins

FEBS Journal

Volumn 278, Issue 6, 2011, Pages 941-954

  Wu, Shengnan ^a   Zhou, Feifan ^a   Zhang, Zhenzhen ^a   Xing, Da ^a  

^a SOUTH CHINA NORMAL UNIVERSITY   (China)

Author keywords

dynamin related protein 1 (Drp1); fission; high fluence low power laser irradiation (HF LPLI); mitofusin 2 (Mfn2); oxidative stress

Indexed keywords

CASPASE 9; CYTOCHROME C; DEHYDROASCORBIC ACID; DYNAMIN RELATED PROTEIN 1; HYBRID PROTEIN; MITOCHONDRIAL PROTEIN; MITOFUSIN 2; PROTEIN BAX; PROTEIN DRP1; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL FUSION; CELL MEMBRANE DEPOLARIZATION; CELL MEMBRANE TRANSPORT; CELL STRAIN COS7; CELL STRUCTURE; CHLOROCEBUS; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; FIBROBLAST; FRAGMENTATION REACTION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; MITOCHONDRIAL RESPIRATION; MOLECULAR DYNAMICS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; CASPASE 9; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; CYTOCHROMES C; GTP PHOSPHOHYDROLASES; HUMANS; LASERS; MEMBRANE PROTEINS; MICROTUBULE-ASSOCIATED PROTEINS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

CERCOPITHECUS AETHIOPS;

EID: 79952520044     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08010.x     Document Type: Article

References (36)

1. Chen H, &, Chan DC, (2005) Emerging functions of mammalian mitochondrial fusion and fission. Hum Mol Genet 14, 283-289.
2. Chan DC, (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell 125, 1241-1252. (Pubitemid 43929096)
3. Liesa M, Palacin M, &, Zorzano A, (2009) Mitochondrial dynamics in mammalian health and disease. Physiol Rev 89, 799-845.
4. Wang X, Su B, Lee H, Li X, Perry G, Smith MA, &, Zhu X, (2009) Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci 29, 9090-9103.
5. Cho D, Nakamura T, Fang J, Cieplak P, Godzik A, Gu Z, &, Lipton SA, (2009) S-nitrosylation of Drp1 mediates β-amyloid-related mitochondrial fission and neuronal injury. Science 324, 102-105.
6. Van Laar VS, &, Berman SB, (2009) Mitochondrial dynamics in Parkinson's disease. Exp Neurol 218, 247-256.
7. Park YY, Lee S, Karbowski M, Neutzner A, Youle RJ, &, Cho H, (2010) Loss of MARCH5 mitochondrial E3 ubiquitin ligase induces cellular senescence through dynamin-related protein 1 and mitofusin 1. J Cell Sci 123, 619-626.
8. Ong S, Subrayan S, Lim SY, Yellon DM, Davidson SM, &, Hausenloy DJ, (2010) Inhibiting mitochondrial fission protects the heart against ischemia/reperfusion injury. Circulation 121, 2012-2022.
9. Romanello V, Guadagnin E, Gomes L, Roder I, Sandri C, Petersen Y, Milan G, Masiero E, Piccolo PD, Foretz M, (2010) Mitochondrial fission and remodelling contributes to muscle atrophy. EMBO J 29, 1774-1785.
10. Karbowski M, &, Youle RJ, (2003) Dynamics of mitochondrial morphology in healthy cells and during apoptosis. Cell Death Differ 10, 870-880. (Pubitemid 36939697)
11. McBride HM, Neuspiel M, &, Wasiak S, (2006) Mitochondria: more than just a power house. Curr Biol 16, 551-560.
12. Westermann B, (2008) Molecular machinery of mitochondrial fusion and fission. J Biol Chem 283, 13501-13505.
13. Wu S, Xing D, Wang F, Chen T, &, Chen W, (2007) Mechanistic study of apoptosis induced by high fluence low-power laser irradiation using fluorescence imaging techniques. J Biomed Opt 12, 064015.
14. Wu S, Xing D, Gao X, &, Chen WR, (2008) High fluence low-power laser irradiation induces mitochondrial permeability transition mediated by reactive oxygen species. J Cell Physiol 218, 603-611.
15. Chu J, Wu S, &, Xing D, (2010) Survivin mediates self-protection through ROS/cdc25c/CDK1 signaling pathway during tumor cell apoptosis induced by high fluence low-power laser irradiation. Cancer Lett 297, 207-219.
16. Karu T, (1999) Primary and secondary mechanisms of action of visible to near-IR radiation on cells. J Photochem Photobiol B 49, 1-17. (Pubitemid 29229670)
17. Karu T, Pyatibrat L, &, Kalendo G, (2004) Photobiological modulation of cell attachment via cytochrome c oxidase. Photochem Photobiol Sci 3, 211-216. (Pubitemid 38855141)
18. Karu T, Pyatibrat L, Kolyakov S, &, Afanasyeva N, (2005) Absorption measurements of a cell monolayer relevant to phototherapy: reduction of cytochrome c oxidase under near IR radiation. J Photochem Photobiol B 81, 98-106. (Pubitemid 41574466)
19. Tanaka A, Kobayashi S, &, Fujiki Y, (2006) Peroxisome division is impaired in a CHO cell mutant with an inactivating point-mutation in dynamin-like protein 1 gene. Exp Cell Res 312, 1671-1684.
20. Cereghetti GM, Stangherlin A, Martins de Brito O, Chang CR, Blackstone C, Bernardi P, &, Scorrano L, (2008) Dephosphorylation by calcineurin regulates translocation of Drp1 to mitochondria. Proc Natl Acad Sci USA 105, 15803-15808.
21. Cho SG, Du Q, Huang S, &, Dong Z, (2010) Drp1 dephosphorylation in ATP depletion-induced mitochondrial injury and tubular cell apoptosis. Am J Physiol Renal Physiol 299, 199-206.
22. Frank S, Gaume B, Bergmann-Leitner ES, Leitner WW, Robert EG, Catez F, Smith CL, &, Youle RJ, (2001) The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell 1, 515-525. (Pubitemid 33586103)
23. Youle RJ, &, Karbowski M, (2005) Mitochondrial fission in apoptosis. Nat Rev Mol Cell Biol 6, 657-663. (Pubitemid 41081269)
24. Karbowski M, Norris KL, Cleland MM, Jeong SY, &, Youle RJ, (2006) Role of Bax and Bak in mitochondrial morphogenesis. Nature 443, 658-662. (Pubitemid 44564703)
25. Arnoult D, Grodet A, Lee YJ, Estaquier J, &, Blackstone C, (2005) Release of OPA1 during apoptosis participates in the rapid and complete release of cytochrome c and subsequent mitochondrial fragmentation. J Biol Chem 280, 35742-35750. (Pubitemid 41532767)
26. Delivani P, Adrain C, Taylor RC, Duriez PJ, &, Martin SJ, (2006) Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics. Mol Cell 21, 761-773. (Pubitemid 43376127)
27. Sheridan C, Delivani P, Cullen SP, &, Martin SJ, (2008) Bax- or Bak-induced mitochondrial fission can be uncoupled from cytochrome c release. Mol Cell 31, 570-585.
28. Chen H, Chomyn A, &, Chan DC, (2005) Disruption of fusion results in mitochondrial heterogeneity and dysfunction. J Biol Chem 280, 26185-26192. (Pubitemid 41022214)
29. Chen F, Detmer SA, Ewald AJ, Griffin EE, Fraser SE, &, Chan DC, (2003) Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol 160, 189-200. (Pubitemid 36254953)
30. Breckenridge DG, Stojanovic M, Marcellus RC, &, Shore GC, (2003) Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol. J Cell Biol 160, 1115-1127. (Pubitemid 36443879)
31. Arnoult A, Rismanchi N, Grodet A, Roberts RG, Seeburg DP, Estaquier J, Sheng M, &, Blackstone C, (2005) Bax/Bak-dependent release of DDP/TIMM8a promotes Drp1-mediated mitochondrial fission and apoptosis during programmed cell death. Curr Biol 15, 2112-2118. (Pubitemid 41739743)
32. Wasiak S, Zunino R, &, McBride HM, (2007) Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death. J Cell Biol 177, 439-450. (Pubitemid 46718273)
33. Karbowski M, Lee YG, Gaume B, Jeong SY, Frank S, Nechushtan A, Santel A, Fuller M, Smith CL, &, Youle RJ, (2002) Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis. J Cell Biol 159, 931-938. (Pubitemid 36055748)
34. Germain M, Mathai JP, McBride HM, &, Shore GC, (2005) Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. EMBO J 24, 1546-1556. (Pubitemid 40646445)
35. Barsoum MJ, Yuan H, Gerencser AA, Liot G, Kushnareva Y, Graber S, Kovacs I, Lee WD, Waggoner J, Cui J, (2006) Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J 25, 3900-3911. (Pubitemid 44300275)
36. Cereghetti GM, Costal V, &, Scorrano L, (2010) Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin. Cell Death Differ 17, 1785-1794.