Hyperglycemia enhances IGF-I-stimulated Src activation via increasing Nox4-derived reactive oxygen species in a PKCζ-dependent manner in vascular smooth muscle cells

Diabetes

Volumn 61, Issue 1, 2012, Pages 104-113

  Xi, Gang ^a   Shen, Xinchun ^a   Maile, Laura A ^a   Wai, Christine ^a   Gollahon, Katherine ^a   Clemmons, David R ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

OXIDOREDUCTASE; P22 PHAGOCYTE OXIDASE; PROTEIN KINASE C ZETA; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SOMATOMEDIN C; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; HYPERGLYCEMIA; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; ENZYME ACTIVATION; HYPERGLYCEMIA; INSULIN-LIKE GROWTH FACTOR I; MALE; MICE; MICE, INBRED C57BL; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NADPH OXIDASE; OXIDATION-REDUCTION; PROTEIN KINASE C; PROTO-ONCOGENE PROTEINS PP60(C-SRC); REACTIVE OXYGEN SPECIES;

EID: 84555188779     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0990     Document Type: Article

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