The p66(shc) adaptor protein controls oxidative stress response and life span in mammals

Nature

Volumn 402, Issue 6759, 1999, Pages 309-313

  Migliaccio, Enrica ^a   Giogio, Marco ^a   Mele, Simonetta ^b   Pelicci, Giuliana ^a   Reboldi, Paolo ^b   Pandolfi, Pier Paolo ^c   Lanfrancone, Luisa ^a   Pelicci, Pier Gluseppe ^a,b  

^a EUROPEAN INSTITUTE OF ONCOLOGY   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

^c MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; HYDROGEN PEROXIDE; PARAQUAT; PROTEIN P21; PROTEIN P53; RAS PROTEIN; REACTIVE OXYGEN METABOLITE; CDKN1A PROTEIN, MOUSE; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; EPIDERMAL GROWTH FACTOR; HERBICIDE; PROTEIN; PROTEIN SERINE THREONINE KINASE; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SRC HOMOLOGY 2 DOMAIN CONTAINING, TRANSFORMING PROTEIN 1; SRC HOMOLOGY 2 DOMAIN-CONTAINING, TRANSFORMING PROTEIN 1; TYROSINE; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE CONTROL; GENE MUTATION; GENE TARGETING; LIFESPAN; MALE; MAMMAL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ULTRAVIOLET RADIATION; ANIMAL; DRUG EFFECT; GENETIC SELECTION; GENETICS; HETEROZYGOTE; HOMOZYGOTE; LONGEVITY; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; RADIATION EXPOSURE; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANIMALS; APOPTOSIS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; EPIDERMAL GROWTH FACTOR; GENE TARGETING; HERBICIDES; HETEROZYGOTE; HOMOZYGOTE; HYDROGEN PEROXIDE; LONGEVITY; MALE; MICE; OXIDATIVE STRESS; PARAQUAT; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; SELECTION (GENETICS); SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; TYROSINE; ULTRAVIOLET RAYS; UP-REGULATION;

EID: 0033581704     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/46311     Document Type: Article

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