Paraoxonase-1 deficiency in mice predisposes to vascular inflammation, oxidative stress, and thrombogenicity in the absence of hyperlipidemia

Cardiovascular Pathology

Volumn 17, Issue 4, 2008, Pages 226-232

  Ng, Dominic S ^a   Chu, Tina ^a   Esposito, Bruno ^b   Hui, Patrick ^a   Connelly, Philip W ^a   Gross, Peter L ^b  

^a ST MICHAEL'S HOSPITAL   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Atherosclerosis; Leukocyte adhesion; Oxidative stress; Paraoxonase; Thrombosis

Indexed keywords

AMYLOID A PROTEIN; ARYLDIALKYLPHOSPHATASE 1; CYTOKINE; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; PADGEM PROTEIN; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENESIS; CAROTID ARTERY THROMBOSIS; CHEMOLUMINESCENCE; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME DEFICIENCY; FEMALE; GENE EXPRESSION; HYPERLIPIDEMIA; KNOCKOUT MOUSE; LEUKOCYTE ADHERENCE; LEUKOCYTE ROLLING; MALE; MICROSCOPY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THROMBOGENICITY; VASCULITIS; WILD TYPE;

ANIMALS; AORTA; ARYLDIALKYLPHOSPHATASE; CELL ADHESION; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GENE SILENCING; INTERCELLULAR ADHESION MOLECULE-1; LEUKOCYTE ROLLING; LEUKOCYTES; LIPIDS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OXIDATIVE STRESS; P-SELECTIN; RNA, MESSENGER; SUPEROXIDES; THROMBOSIS; VASCULAR CELL ADHESION MOLECULE-1; VASCULITIS;

EID: 47149093201     PISSN: 10548807     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carpath.2007.10.001     Document Type: Article

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