NADPH Oxidase 4 (Nox4) suppresses mitochondrial biogenesis and bioenergetics in lung fibroblasts via a nuclear factor erythroid-derived 2-like 2 (Nrf2)-dependent pathway

Journal of Biological Chemistry

Volumn 292, Issue 7, 2017, Pages 3029-3038

  Bernard, Karen ^a   Logsdon, Naomi J ^a   Miguel, Veronica ^e   Benavides, Gloria A ^b,c   Zhang, Jianhua ^b   Carter, A Brent ^c   Darley Usmar, Victor M ^a,d   Thannickal, Victor J ^b,c  

^a Allergy and Critical Care Medicine   (United States)

^b Department of Pathology ^*  (United States)

^c UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^d BIRMINGHAM VA MEDICAL CENTER   (United States)

^e UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIOLOGICAL ORGANS; BIOSYNTHESIS; CELL CULTURE; CYTOLOGY; FIBROBLASTS; PHYSIOLOGY;

CELLULAR DIFFERENTIATION; HUMAN LUNG FIBROBLASTS; MITOCHONDRIAL BIOENERGETICS; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL FUNCTION; MITOCHONDRIAL OXYGEN CONSUMPTION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; VOLTAGE-DEPENDENT ANION CHANNELS;

PLANTS (BOTANY);

CITRATE SYNTHASE; MITOCHONDRIAL TRANSCRIPTION FACTOR A; MYC PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; TRANSCRIPTION FACTOR NRF2; VOLTAGE DEPENDENT ANION CHANNEL; DNA BINDING PROTEIN; HIGH MOBILITY GROUP PROTEIN; MESSENGER RNA; NFE2L2 PROTEIN, MOUSE; NOX4 PROTEIN, MOUSE; PPARGC1A PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; TFAM PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; ENZYME INHIBITION; HOST RESISTANCE; HUMAN; HUMAN CELL; IMMUNOBLOTTING; LUNG FIBROBLAST; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL RESPIRATION; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM; RNA INTERFERENCE; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CYTOLOGY; ENERGY METABOLISM; GENE SILENCING; GENETICS; KNOCKOUT MOUSE; LUNG; METABOLISM; ORGANELLE BIOGENESIS; PHYSIOLOGY;

ANIMALS; DNA-BINDING PROTEINS; ENERGY METABOLISM; GENE SILENCING; HIGH MOBILITY GROUP PROTEINS; HUMANS; LUNG; MICE; MICE, KNOCKOUT; NADPH OXIDASE; NF-E2-RELATED FACTOR 2; ORGANELLE BIOGENESIS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA COACTIVATOR 1-ALPHA; RNA, MESSENGER;

EID: 85013478403     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M116.752261     Document Type: Article

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