Uncoupling protein-2 prevents neuronal death and diminishes brain dysfunction after stroke and brain trauma

Nature Medicine

Volumn 9, Issue 8, 2003, Pages 1062-1068

  Mattiasson, Gustav ^a   Shamloo, Mehrdad ^b   Gido, Gunilla ^a   Mathi, Kavitha ^b   Tomasevic, Gregor ^a   Yi, Saili ^b   Warden, Craig H ^c   Castilho, Roger F ^d   Melcher, Thorsten ^b   Gonzalez Zulueta, Mirella ^b   Nikolich, Karoly ^b   Wieloch, Tadeusz ^a  

^a LUND UNIVERSITY   (Sweden)

^b AGY Therapeutics Inc   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 DINITROPHENOL; BRAIN PROTEIN; CASPASE 3; CELL MEMBRANE PROTEIN; COMPLEMENTARY DNA; GLUCOSE; OXYGEN; PALMITIC ACID; REACTIVE OXYGEN METABOLITE; UNCOUPLING PROTEIN 1; UNCOUPLING PROTEIN 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BIOSYNTHESIS; BRAIN DYSFUNCTION; BRAIN INJURY; BRAIN LEVEL; BRAIN MITOCHONDRION; BRAIN NERVE CELL; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DETERMINATION; DNA MICROARRAY; ENERGY METABOLISM; ENZYME INHIBITION; GENE FUNCTION; GENE IDENTIFICATION; HYBRIDIZATION; MITOCHONDRIAL RESPIRATION; MOLECULAR CLONING; MOUSE; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; RAT; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STROKE; THERMOGENESIS;

ANIMALS; BRAIN; BRAIN INJURIES; CASPASE 3; CASPASES; CELL DEATH; CELLS, CULTURED; CEREBROVASCULAR ACCIDENT; HUMANS; ION CHANNELS; ISCHEMIA; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NEURONS; NEUROPROTECTIVE AGENTS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEINS; RATS; REACTIVE OXYGEN SPECIES; UNCOUPLING AGENTS;

ANIMALIA;

EID: 0041464712     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm903     Document Type: Article

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