Shedding of the Mer tyrosine kinase receptor is mediated by ADAM17 protein through a pathway involving reactive oxygen species, protein kinase Cδ, and p38 Mitogen-activated Protein Kinase (MAPK)

Journal of Biological Chemistry

Volumn 286, Issue 38, 2011, Pages 33335-33344

  Thorp, Edward ^a   Vaisar, Tomas ^b   Subramanian, Manikandan ^a   Mautner, Lauren ^a   Blobel, Carl ^c   Tabas, Ira ^a  

^a Howard Hughes Medical Institute   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ECTODOMAIN; IN-VITRO; IN-VIVO; INFLAMMATORY SIGNALING; INTEGRAL MEMBRANE PROTEINS; INTRACELLULAR SIGNALING PATHWAYS; METALLOPROTEINASES; MOUSE MODELS; MURINE MACROPHAGES; N-ACETYL CYSTEINE; NADPH OXIDASE; P38 MITOGEN-ACTIVATED PROTEIN KINASE; PATTERN RECOGNITION RECEPTORS; PHAGOCYTIC CELLS; PROTEIN KINASE C; PROTEOLYTIC CLEAVAGE; REACTIVE OXYGEN SPECIES; TYROSINE KINASE;

AMINO ACIDS; BIOLOGICAL MEMBRANES; ENZYME ACTIVITY; MAMMALS; PATTERN RECOGNITION; SIGNALING;

PROTEINS;

ADAM PROTEIN; ADAM17 PROTEIN; DISINTEGRIN; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYELOID DIFFERENTIATION FACTOR 88; PATTERN RECOGNITION RECEPTOR; PROLINE; PROTEIN KINASE C DELTA; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TOLL LIKE RECEPTOR 4; TYROSINE KINASE RECEPTOR; TYROSINE KINASE RECEPTOR MER; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EFFEROCYTOSIS; ENZYME ACTIVATION; FEMALE; MACROPHAGE; MOUSE; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN SHEDDING; PROTEIN TARGETING; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS;

ADAM PROTEINS; ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMINO ACID SEQUENCE; ANIMALS; LIPOPOLYSACCHARIDES; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MYELOID DIFFERENTIATION FACTOR 88; NADP; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROLINE; PROTEIN KINASE C-DELTA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS; REACTIVE OXYGEN SPECIES; RECEPTOR PROTEIN-TYROSINE KINASES; SEQUENCE DELETION; SIGNAL TRANSDUCTION; SOLUBILITY; TOLL-LIKE RECEPTOR 4;

MURINAE; MUS;

EID: 80053030745     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.263020     Document Type: Article

References (65)

1. Nagata, K., Ohashi, K., Nakano, T., Arita, H., Zong, C., Hanafusa, H., and Mizuno, K. (1996) J. Biol. Chem. 271, 30022-30027
2. Uehara, H., and Shacter, E. (2008) J. Immunol. 180, 2522-2530
3. Scott, R. S., McMahon, E. J., Pop, S. M., Reap, E. A., Caricchio, R., Cohen, P. L., Earp, H. S., and Matsushima, G. K. (2001) Nature 411, 207-211
4. Chen, C., Li, Q., Darrow, A. L., Wang, Y., Derian, C. K., Yang, J., de Garavilla, L., Andrade-Gordon, P., and Damiano, B. P. (2004) Arterioscler. Thromb. Vasc. Biol. 24, 1118-1123
5. Anwar, A., Keating, A. K., Joung, D., Sather, S., Kim, G. K., Sawczyn, K. K., Brandão, L., Henson, P. M., and Graham, D. K. (2009) J. Leukoc. Biol. 86, 73-79
6. Ishimoto, Y., Ohashi, K., Mizuno, K., and Nakano, T. (2000) J. Biochem. 127, 411-417
7. Wu, Y., Singh, S., Georgescu, M. M., and Birge, R. B. (2005) J. Cell Sci. 118, 539-553
8. Graham, D. K., Dawson, T. L., Mullaney, D. L., Snodgrass, H. R., and Earp, H. S. (1994) Cell Growth Differ. 5, 647-657
9. Gal, A., Li, Y., Thompson, D. A., Weir, J., Orth, U., Jacobson, S. G., Apfelstedt-Sylla, E., and Vollrath, D. (2000) Nat. Genet. 26, 270-271
10. Vollrath, D., Feng, W., Duncan, J. L., Yasumura, D., D'Cruz, P. M., Chappelow, A., Matthes, M. T., Kay, M. A., and LaVail, M. M. (2001) Proc. Natl. Acad. Sci. U.S.A. 98, 12584-12589
11. Cohen, P. L., Caricchio, R., Abraham, V., Camenisch, T. D., Jennette, J. C., Roubey, R. A., Earp, H. S., Matsushima, G., and Reap, E. A. (2002) J. Exp. Med. 196, 135-140
12. Thorp, E., Cui, D., Schrijvers, D. M., Kuriakose, G., and Tabas, I. (2008) Arterioscler. Thromb. Vasc. Biol. 28, 1421-1428
13. Graham, D. K., Bowman, G. W., Dawson, T. L., Stanford, W. L., Earp, H. S., and Snodgrass, H. R. (1995) Oncogene 10, 2349-2359
14. Tibrewal, N., Wu, Y., D'mello, V., Akakura, R., George, T. C., Varnum, B., and Birge, R. B. (2008) J. Biol. Chem. 283, 3618-3627
15. Lemke, G., and Rothlin, C. V. (2008) Nat. Rev. Immunol. 8, 327-336
16. Sather, S., Kenyon, K. D., Lefkowitz, J. B., Liang, X., Varnum, B. C., Henson, P. M., and Graham, D. K. (2007) Blood 109, 1026-1033
17. Thorp, E., Schrijvers, D., and Tabas, I. (2010) Abstracts: Arteriosclerosis, Thrombosis, and Vascular Biology 2010 Scientific Session, Abstract 15, Lippincott Williams & Wilkins, Philadelphia
18. Hurtado, B., Muñoz, X., Recarte-Pelz, P., García, N., Luque, A., Krupinski, J., Sala, N., and García de Frutos, P. (2011) Thromb. Haemost. 105, 873-882
19. Blobel, C. P. (2005) Nat. Rev. Mol. Cell Biol. 6, 32-43
20. Müllberg, J., Rauch, C. T., Wolfson, M. F., Castner, B., Fitzner, J. N., Otten-Evans, C., Mohler, K. M., Cosman, D., and Black, R. A. (1997) FEBS Lett. 401, 235-238
21. Black, R. A., Rauch, C. T., Kozlosky, C. J., Peschon, J. J., Slack, J. L., Wolfson, M. F., Castner, B. J., Stocking, K. L., Reddy, P., Srinivasan, S., Nelson, N., Boiani, N., Schooley, K. A., Gerhart, M., Davis, R., Fitzner, J. N., Johnson, R. S., Paxton, R. J., March, C. J., and Cerretti, D. P. (1997) Nature 385, 729-733
22. Moss, M. L., Jin, S. L., Milla, M. E., Bickett, D. M., Burkhart, W., Carter, H. L., Chen, W. J., Clay, W. C., Didsbury, J. R., Hassler, D., Hoffman, C. R., Kost, T. A., Lambert, M. H., Leesnitzer, M. A., McCauley, P., McGeehan, G., Mitchell, J., Moyer, M., Pahel, G., Rocque, W., Overton, L. K., Schoenen, F., Seaton, T., Su, J. L., and Becherer, J. D. (1997) Nature 385, 733-736
23. Murphy, G. (2008) Nat. Rev. Cancer 8, 929-941
24. Le Gall, S. M., Maretzky, T., Issuree, P. D., Niu, X. D., Reiss, K., Saftig, P., Khokha, R., Lundell, D., and Blobel, C. P. (2010) J. Cell Sci. 123, 3913-3922
25. Tabas, I. (2010) Nat. Rev. Immunol. 10, 36-46
26. Horiuchi, K., Kimura, T., Miyamoto, T., Takaishi, H., Okada, Y., Toyama, Y., and Blobel, C. P. (2007) J. Immunol. 179, 2686-2689
27. Li, Y., and Tabas, I. (2006) J. Leukoc. Biol. 81, 483-491
28. Glenn, G., and van der Geer, P. (2008) FEBS Lett. 582, 911-915
29. Pabst, M. J., and Johnston, R. B., Jr. (1980) J. Exp. Med. 151, 101-114
30. Ushio-Fukai, M. (2006) Sci. STKE 2006, re8
31. Reyland, M. E. (2009) Front. Biosci. 14, 2386-2399
32. Young, L. H., Balin, B. J., and Weis, M. T. (2005) Cardiovasc. Drug Rev. 23, 255-272
33. Crowe, P. D., Walter, B. N., Mohler, K. M., Otten-Evans, C., Black, R. A., and Ware, C. F. (1995) J. Exp. Med. 181, 1205-1210
34. Le Gall, S. M., Bobé, P., Reiss, K., Horiuchi, K., Niu, X. D., Lundell, D., Gibb, D. R., Conrad, D., Saftig, P., and Blobel, C. P. (2009) Mol. Biol. Cell 20, 1785-1794
35. Soond, S. M., Everson, B., Riches, D. W., and Murphy, G. (2005) J. Cell Sci. 118, 2371-2380
36. Díaz-Rodríguez, E., Montero, J. C., Esparís-Ogando, A., Yuste, L., and Pandiella, A. (2002) Mol. Biol. Cell 13, 2031-2044
37. Xu, P., and Derynck, R. (2010) Mol. Cell 37, 551-566
38. Rousseau, S., Papoutsopoulou, M., Symons, A., Cook, D., Lucocq, J. M., Prescott, A. R., O'Garra, A., Ley, S. C., and Cohen, P. (2008) J. Cell Sci. 121, 149-154
39. Raingeaud, J., Whitmarsh, A. J., Barrett, T., Dérijard, B., and Davis, R. J. (1996) Mol. Cell Biol. 16, 1247-1255
40. Althoff, K., Reddy, P., Voltz, N., Rose-John, S., and Müllberg, J. (2000) Eur. J. Biochem. 267, 2624-2631
41. Becherer, J. D., and Blobel, C. P. (2003) Curr. Top. Dev. Biol. 54, 101-123
42. Caescu, C. I., Jeschke, G. R., and Turk, B. E. (2009) Biochem. J. 424, 79-88
43. O'Bryan, J. P., Fridell, Y. W., Koski, R., Varnum, B., and Liu, E. T. (1995) J. Biol. Chem. 270, 551-557
44. Costa, M., Bellosta, P., and Basilico, C. (1996) J. Cell Physiol. 168, 737-744
45. Gómez, M. I., Sokol, S. H., Muir, A. B., Soong, G., Bastien, J., and Prince, A. S. (2005) J. Immunol. 175, 1930-1936
46. Bostanci, N., Reddi, D., Rangarajan, M., Curtis, M. A., and Belibasakis, G. N. (2009) Oral Microbiol. Immunol. 24, 146-151
47. Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K., and Akira, S. (1999) Immunity 11, 443-451
48. Brandl, K., Sun, L., Neppl, C., Siggs, O. M., Le Gall, S. M., Tomisato, W., Li, X., Du, X., Maennel, D. N., Blobel, C. P., and Beutler, B. (2010) Proc. Natl. Acad. Sci. U.S.A. 107, 19967-19972
49. Koff, J. L., Shao, M. X., Ueki, I. F., and Nadel, J. A. (2008) Am. J. Physiol. Lung Cell Mol. Physiol. 294, L1068-L1075
50. Myers, T. J., Brennaman, L. H., Stevenson, M., Higashiyama, S., Russell, W. E., Lee, D. C., and Sunnarborg, S. W. (2009) Mol. Biol. Cell 20, 5236-5249
51. Fan, J., Frey, R. S., and Malik, A. B. (2003) J. Clin. Invest. 112, 1234-1243
52. Park, H. S., Jung, H. Y., Park, E. Y., Kim, J., Lee, W. J., and Bae, Y. S. (2004) J. Immunol. 173, 3589-3593
53. Wang, Y., Herrera, A. H., Li, Y., Belani, K. K., and Walcheck, B. (2009) J. Immunol. 182, 2449-2457
54. Zhang, Z., Oliver, P., Lancaster, J. R., Jr., Schwarzenberger, P. O., Joshi, M. S., Cork, J., and Kolls, J. K. (2001) FASEB J. 15, 303-305
55. Shao, M. X., and Nadel, J. A. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 767-772
56. Kanthasamy, A. G., Kitazawa, M., Kanthasamy, A., and Anantharam, V. (2003) Antioxid. Redox Signal. 5, 609-620
57. Konishi, H., Tanaka, M., Takemura, Y., Matsuzaki, H., Ono, Y., Kikkawa, U., and Nishizuka, Y. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 11233-11237
58. Chen, C. L., Chan, P. C., Wang, S. H., Pan, Y. R., and Chen, H. C. (2010) J. Cell Sci. 123, 2901-2913
59. McGettrick, A. F., Brint, E. K., Palsson-McDermott, E. M., Rowe, D. C., Golenbock, D. T., Gay, N. J., Fitzgerald, K. A., and O'Neill, L. A. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 9196-9201
60. Kubo-Murai, M., Hazeki, K., Sukenobu, N., Yoshikawa, K., Nigorikawa, K., Inoue, K., Yamamoto, T., Matsumoto, M., Seya, T., Inoue, N., and Hazeki, O. (2007) Mol. Immunol. 44, 2257-2264
61. Lee, M. C., Wei, S. C., Tsai-Wu, J. J., Wu, C. H., and Tsao, P. N. (2008) J. Leukoc. Biol. 84, 835-841
62. Ziegler, K., Kurz, C. L., Cypowyj, S., Couillault, C., Pophillat, M., Pujol, N., and Ewbank, J. J. (2009) Cell Host Microbe 5, 341-352
63. Reddy, P., Slack, J. L., Davis, R., Cerretti, D. P., Kozlosky, C. J., Blanton, R. A., Shows, D., Peschon, J. J., and Black, R. A. (2000) J. Biol. Chem. 275, 14608-14614
64. Aderka, D., Engelmann, H., Maor, Y., Brakebusch, C., and Wallach, D. (1992) J. Exp. Med. 175, 323-329
65. Feng, X., Deng, T., Zhang, Y., Su, S., Wei, C., and Han, D. (2011) Immunology 132, 287-295