Augmenting brain metabolism to increase macro- and chaperone-mediated autophagy for decreasing neuronal proteotoxicity and aging

Progress in Neurobiology

Volumn 156, Issue , 2017, Pages 90-106

  Loos, Ben ^a   Klionsky, Daniel J ^b   Wong, Esther ^c  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF MICHIGAN   (United States)

^c NANYANG TECHNOLOGICAL UNIVERSITY   (Singapore)

Author keywords

Autophagic flux; Caloric restriction; Exercise; Ketone bodies; Longevity; Neurodegeneration

Indexed keywords

KETONE BODY; CHAPERONE;

AGING; BRAIN FUNCTION; BRAIN METABOLISM; CALORIC RESTRICTION; CHAPERONE-MEDIATED AUTOPHAGY; EXERCISE; FUNGAL METABOLISM; HUMAN; MACROAUTOPHAGY; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; REVIEW; SACCHAROMYCES CEREVISIAE; ANIMAL; AUTOPHAGY; BRAIN; LONGEVITY; LYSOSOME; METABOLISM; NEUROLOGIC DISEASE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

AGING; ANIMALS; AUTOPHAGY; BRAIN; CALORIC RESTRICTION; EXERCISE; HUMANS; KETONE BODIES; LONGEVITY; LYSOSOMES; MOLECULAR CHAPERONES; NERVOUS SYSTEM DISEASES;

EID: 85019908850     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2017.05.001     Document Type: Review

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