-
1
-
-
0032568534
-
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies
-
Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M (1998) alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies. Proc Natl Acad Sci U S A 95: 6469-6473.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
2
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer W, Przedborski S (2003) Parkinson's disease: mechanisms and models. Neuron 39: 889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
3
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, et al. (2000) Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science 290: 985-989.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
-
4
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, et al. (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276: 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
-
5
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R, Kuhn W, Muller T, Woitalla D, Graeber M, et al. (1998) Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 18: 106-108.
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
-
6
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz JJ, Alegre J, Gomez-Esteban JC, Lezcano E, Ros R, et al. (2004) The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann Neurol 55: 164-173.
-
(2004)
Ann Neurol
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
-
7
-
-
0242300619
-
alpha-Synuclein locus triplication causes Parkinson's disease
-
Singleton AB, Singleton A, Hague S, Kachergus J, Hulihan M, et al. (2003) alpha-Synuclein locus triplication causes Parkinson's disease. Science 302: 841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Singleton, A.2
Hague, S.3
Kachergus, J.4
Hulihan, M.5
-
8
-
-
4644290985
-
Alpha-synuclein locus duplication as a cause of familial Parkinson's disease
-
Chartier-Harlin MC, Kachergus J, Roumier C, Mouroux V, Douay X, et al. (2004) Alpha-synuclein locus duplication as a cause of familial Parkinson's disease. Lancet 364: 1167-1169.
-
(2004)
Lancet
, vol.364
, pp. 1167-1169
-
-
Chartier-Harlin, M.C.1
Kachergus, J.2
Roumier, C.3
Mouroux, V.4
Douay, X.5
-
9
-
-
4644236043
-
Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease
-
Ibanez P, Bonnet AM, Debarges B, Lohmann E, Tison F, et al. (2004) Causal relation between alpha-synuclein gene duplication and familial Parkinson's disease. Lancet 364: 1169-1171.
-
(2004)
Lancet
, vol.364
, pp. 1169-1171
-
-
Ibanez, P.1
Bonnet, A.M.2
Debarges, B.3
Lohmann, E.4
Tison, F.5
-
10
-
-
33746869343
-
Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease
-
Maraganore DM, de Andrade M, Elbaz A, Farrer MJ, Ioannidis JP, et al. (2006) Collaborative analysis of alpha-synuclein gene promoter variability and Parkinson disease. Jama 296: 661-670.
-
(2006)
Jama
, vol.296
, pp. 661-670
-
-
Maraganore, D.M.1
de Andrade, M.2
Elbaz, A.3
Farrer, M.J.4
Ioannidis, J.P.5
-
11
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, et al. (1997) Alpha-synuclein in Lewy bodies. Nature 388: 839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
-
12
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H, Del Tredici K, Rub U, de Vos RA, Jansen Steur EN, et al. (2003) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24: 197-211.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
de Vos, R.A.4
Jansen Steur, E.N.5
-
13
-
-
33751118534
-
Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease?
-
Chu Y, Kordower JH (2007) Age-associated increases of alpha-synuclein in monkeys and humans are associated with nigrostriatal dopamine depletion: Is this the target for Parkinson's disease? Neurobiol Dis 25: 134-149.
-
(2007)
Neurobiol Dis
, vol.25
, pp. 134-149
-
-
Chu, Y.1
Kordower, J.H.2
-
16
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders
-
Caughey B, Lansbury PT (2003) Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders. Annu Rev Neurosci 26: 267-298.
-
(2003)
Annu Rev Neurosci
, vol.26
, pp. 267-298
-
-
Caughey, B.1
Lansbury, P.T.2
-
18
-
-
0035894855
-
Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
-
Stefanis L, Larsen KE, Rideout HJ, Sulzer D, Greene LA (2001) Expression of A53T mutant but not wild-type alpha-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J Neurosci 21: 9549-9560.
-
(2001)
J Neurosci
, vol.21
, pp. 9549-9560
-
-
Stefanis, L.1
Larsen, K.E.2
Rideout, H.J.3
Sulzer, D.4
Greene, L.A.5
-
19
-
-
33746533924
-
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models
-
Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, et al. (2006) Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science 313: 324-328.
-
(2006)
Science
, vol.313
, pp. 324-328
-
-
Cooper, A.A.1
Gitler, A.D.2
Cashikar, A.3
Haynes, C.M.4
Hill, K.J.5
-
20
-
-
33748502763
-
Alpha-synuclein overexpression increases cytosolic catecholamine concentration
-
Mosharov EV, Staal RG, Bove J, Prou D, Hananiya A, et al. (2006) Alpha-synuclein overexpression increases cytosolic catecholamine concentration. J Neurosci 26: 9304-9311.
-
(2006)
J Neurosci
, vol.26
, pp. 9304-9311
-
-
Mosharov, E.V.1
Staal, R.G.2
Bove, J.3
Prou, D.4
Hananiya, A.5
-
21
-
-
4344659685
-
Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy
-
Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D (2004) Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 305: 1292-1295.
-
(2004)
Science
, vol.305
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stefanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
22
-
-
1842583789
-
Development by self-digestion: Molecular mechanisms and biological functions of autophagy
-
Levine B, Klionsky DJ (2004) Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.J.2
-
23
-
-
0442323561
-
Autophagy: In sickness and in health
-
Cuervo AM (2004) Autophagy: in sickness and in health. Trends Cell Biol 14: 70-77.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 70-77
-
-
Cuervo, A.M.1
-
24
-
-
0029837453
-
A receptor for the selective uptake and degradation of proteins by lysosomes
-
Cuervo AM, Dice JF (1996) A receptor for the selective uptake and degradation of proteins by lysosomes. Science 273: 501-503.
-
(1996)
Science
, vol.273
, pp. 501-503
-
-
Cuervo, A.M.1
Dice, J.F.2
-
25
-
-
4344673498
-
Mechanisms of chaperone-mediated autophagy
-
Majeski AE, Dice JF (2004) Mechanisms of chaperone-mediated autophagy. Int J Biochem Cell Biol 36: 2435-2444.
-
(2004)
Int J Biochem Cell Biol
, vol.36
, pp. 2435-2444
-
-
Majeski, A.E.1
Dice, J.F.2
-
27
-
-
53049098471
-
Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
-
Vogiatzi T, Xilouri M, Vekrellis K, Stefanis L (2008) Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells. J Biol Chem 283: 23542-23556.
-
(2008)
J Biol Chem
, vol.283
, pp. 23542-23556
-
-
Vogiatzi, T.1
Xilouri, M.2
Vekrellis, K.3
Stefanis, L.4
-
28
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey UB, Nie Z, Batlevi Y, McCray BA, Ritson GP, et al. (2007) HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature 447: 859-863.
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
-
29
-
-
56449083411
-
Autophagy in neurodegeneration and development
-
Winslow AR, Rubinsztein DC (2008) Autophagy in neurodegeneration and development. Biochim Biophys Acta 1782: 723-729.
-
(2008)
Biochim Biophys Acta
, vol.1782
, pp. 723-729
-
-
Winslow, A.R.1
Rubinsztein, D.C.2
-
30
-
-
44149124887
-
Autophagy in neuroprotection and neurodegeneration: A question of balance
-
Cherra SJ, Chu CT (2008) Autophagy in neuroprotection and neurodegeneration: A question of balance. Future Neurol 3: 309-323.
-
(2008)
Future Neurol
, vol.3
, pp. 309-323
-
-
Cherra, S.J.1
Chu, C.T.2
-
31
-
-
57649228468
-
Autophagy and cell death in model organisms
-
Kourtis N, Tavernarakis N (2009) Autophagy and cell death in model organisms. Cell Death Differ 16: 21-30.
-
(2009)
Cell Death Differ
, vol.16
, pp. 21-30
-
-
Kourtis, N.1
Tavernarakis, N.2
-
32
-
-
33847048316
-
Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death
-
Zhu JH, Horbinski C, Guo F, Watkins S, Uchiyama Y, et al. (2007) Regulation of autophagy by extracellular signal-regulated protein kinases during 1-methyl-4-phenylpyridinium-induced cell death. Am J Pathol 170: 75-86.
-
(2007)
Am J Pathol
, vol.170
, pp. 75-86
-
-
Zhu, J.H.1
Horbinski, C.2
Guo, F.3
Watkins, S.4
Uchiyama, Y.5
-
33
-
-
58449101589
-
-
PLoS
-
Ling D, Song HJ, Garza D, Neufeld TP, Salvaterra PM (2009) Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila. PLoS ONE 4: e4201.
-
(2009)
Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila
, vol.ONE 4
-
-
Ling, D.1
Song, H.J.2
Garza, D.3
Neufeld, T.P.4
Salvaterra, P.M.5
-
34
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, et al. (2006) Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 441: 880-884.
-
(2006)
Nature
, vol.441
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.5
-
35
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T, Nakamura K, Matsui M, Yamamoto A, Nakahara Y, et al. (2006) Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441: 885-889.
-
(2006)
Nature
, vol.441
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
-
36
-
-
0041589248
-
Alpha-Synuclein is degraded by both autophagy and the proteasome
-
Webb JL, Ravikumar B, Atkins J, Skepper JN, Rubinsztein DC (2003) Alpha-Synuclein is degraded by both autophagy and the proteasome. J Biol Chem 278: 25009-25013.
-
(2003)
J Biol Chem
, vol.278
, pp. 25009-25013
-
-
Webb, J.L.1
Ravikumar, B.2
Atkins, J.3
Skepper, J.N.4
Rubinsztein, D.C.5
-
37
-
-
27644466759
-
Autophagy and signaling: Their role in cell survival and cell death
-
Codogno P, Meijer AJ (2005) Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 12(Suppl 2): 1509-1518.
-
(2005)
Cell Death Differ
, vol.12
, Issue.SUPPL. 2
, pp. 1509-1518
-
-
Codogno, P.1
Meijer, A.J.2
-
38
-
-
20344387475
-
Autophagy: Dual roles in life and death?
-
Baehrecke EH (2005) Autophagy: dual roles in life and death? Nat Rev Mol Cell Biol 6: 505-510.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 505-510
-
-
Baehrecke, E.H.1
-
39
-
-
0034489853
-
Alpha-synuclein and Parkinson's disease
-
Lucking CB, Brice A (2000) Alpha-synuclein and Parkinson's disease. Cell Mol Life Sci 57: 1894-1908.
-
(2000)
Cell Mol Life Sci
, vol.57
, pp. 1894-1908
-
-
Lucking, C.B.1
Brice, A.2
-
40
-
-
11144353869
-
Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons
-
Saha AR, Hill J, Utton MA, Asuni AA, Ackerley S, et al. (2004) Parkinson's disease alpha-synuclein mutations exhibit defective axonal transport in cultured neurons. J Cell Sci 117: 1017-1024.
-
(2004)
J Cell Sci
, vol.117
, pp. 1017-1024
-
-
Saha, A.R.1
Hill, J.2
Utton, M.A.3
Asuni, A.A.4
Ackerley, S.5
-
41
-
-
0036550101
-
Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system
-
Kirik D, Rosenblad C, Burger C, Lundberg C, Johansen TE, et al. (2002) Parkinson-like neurodegeneration induced by targeted overexpression of alpha-synuclein in the nigrostriatal system. J Neurosci 22: 2780-2791.
-
(2002)
J Neurosci
, vol.22
, pp. 2780-2791
-
-
Kirik, D.1
Rosenblad, C.2
Burger, C.3
Lundberg, C.4
Johansen, T.E.5
-
42
-
-
0036679197
-
alpha-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease
-
Lo Bianco C, Ridet JL, Schneider BL, Deglon N, Aebischer P (2002) alpha-Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease. Proc Natl Acad Sci U S A 99: 10813-10818.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10813-10818
-
-
Lo Bianco, C.1
Ridet, J.L.2
Schneider, B.L.3
Deglon, N.4
Aebischer, P.5
-
43
-
-
38849174979
-
Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy
-
Martinez-Vicente M, Talloczy Z, Kaushik S, Massey AC, Mazzulli J, et al. (2008) Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. J Clin Invest 118: 777-788.
-
(2008)
J Clin Invest
, vol.118
, pp. 777-788
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Kaushik, S.3
Massey, A.C.4
Mazzulli, J.5
-
44
-
-
20444401187
-
Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations
-
Norris EH, Giasson BI, Hodara R, Xu S, Trojanowski JQ, et al. (2005) Reversible inhibition of alpha-synuclein fibrillization by dopaminochrome-mediated conformational alterations. J Biol Chem 280: 21212-21219.
-
(2005)
J Biol Chem
, vol.280
, pp. 21212-21219
-
-
Norris, E.H.1
Giasson, B.I.2
Hodara, R.3
Xu, S.4
Trojanowski, J.Q.5
-
45
-
-
15744405993
-
Synuclein, dopamine and oxidative stress: Co-conspirators in Parkinson's disease?
-
Maguire-Zeiss KA, Short DW, Federoff HJ (2005) Synuclein, dopamine and oxidative stress: co-conspirators in Parkinson's disease? Brain Res Mol Brain Res 134: 18-23.
-
(2005)
Brain Res Mol Brain Res
, vol.134
, pp. 18-23
-
-
Maguire-Zeiss, K.A.1
Short, D.W.2
Federoff, H.J.3
-
46
-
-
0037844598
-
3,4-dihydroxyphenylacetaldehyde: A potential target for neuroprotective therapy in Parkinson's disease
-
Burke WJ (2003) 3,4-dihydroxyphenylacetaldehyde: a potential target for neuroprotective therapy in Parkinson's disease. Curr Drug Targets CNS Neurol Disord 2: 143-148.
-
(2003)
Curr Drug Targets CNS Neurol Disord
, vol.2
, pp. 143-148
-
-
Burke, W.J.1
-
47
-
-
58149215720
-
Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy
-
Yang Q, She H, Gearing M, Colla E, Lee M, et al. (2009) Regulation of neuronal survival factor MEF2D by chaperone-mediated autophagy. Science 323: 124-127.
-
(2009)
Science
, vol.323
, pp. 124-127
-
-
Yang, Q.1
She, H.2
Gearing, M.3
Colla, E.4
Lee, M.5
-
48
-
-
33645829816
-
Consequences of the selective blockage of chaperone-mediated autophagy
-
Massey AC, Kaushik S, Sovak G, Kiffin R, Cuervo AM (2006) Consequences of the selective blockage of chaperone-mediated autophagy. Proc Natl Acad Sci U S A 103: 5805-5810.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5805-5810
-
-
Massey, A.C.1
Kaushik, S.2
Sovak, G.3
Kiffin, R.4
Cuervo, A.M.5
-
49
-
-
33747388358
-
Lysosomal system pathways: Genes to neurodegeneration in Alzheimer's disease
-
Nixon RA, Cataldo AM (2006) Lysosomal system pathways: genes to neurodegeneration in Alzheimer's disease. J Alzheimers Dis 9: 277-289.
-
(2006)
J Alzheimers Dis
, vol.9
, pp. 277-289
-
-
Nixon, R.A.1
Cataldo, A.M.2
-
50
-
-
28544435485
-
Lysosomes and autophagy in cell death control
-
Kroemer G, Jaattela M (2005) Lysosomes and autophagy in cell death control. Nat Rev Cancer 5: 886-897.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 886-897
-
-
Kroemer, G.1
Jaattela, M.2
-
51
-
-
20044385920
-
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease
-
Stokin GB, Lillo C, Falzone TL, Brusch RG, Rockenstein E, et al. (2005) Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease. Science 307: 1282-1288.
-
(2005)
Science
, vol.307
, pp. 1282-1288
-
-
Stokin, G.B.1
Lillo, C.2
Falzone, T.L.3
Brusch, R.G.4
Rockenstein, E.5
-
52
-
-
26444515364
-
Autophagy and its possible roles in nervous system diseases, damage and repair
-
Rubinsztein DC, DiFiglia M, Heintz N, Nixon RA, Qin ZH, et al. (2005) Autophagy and its possible roles in nervous system diseases, damage and repair. Autophagy 1: 11-22.
-
(2005)
Autophagy
, vol.1
, pp. 11-22
-
-
Rubinsztein, D.C.1
DiFiglia, M.2
Heintz, N.3
Nixon, R.A.4
Qin, Z.H.5
-
53
-
-
33747881231
-
Autophagy in neurodegenerative disease: Friend, foe or turncoat?
-
Nixon RA (2006) Autophagy in neurodegenerative disease: friend, foe or turncoat? Trends Neurosci 29: 528-535.
-
(2006)
Trends Neurosci
, vol.29
, pp. 528-535
-
-
Nixon, R.A.1
-
54
-
-
39549117093
-
Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells
-
Plowey ED, Cherra SJ 3rd, Liu YJ, Chu CT (2008) Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells. J Neurochem 105: 1048-1056.
-
(2008)
J Neurochem
, vol.105
, pp. 1048-1056
-
-
Plowey, E.D.1
Cherra 3rd, S.J.2
Liu, Y.J.3
Chu, C.T.4
-
55
-
-
33947505619
-
Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo
-
Periquet M, Fulga T, Myllykangas L, Schlossmacher MG, Feany MB (2007) Aggregated alpha-synuclein mediates dopaminergic neurotoxicity in vivo. J Neurosci 27: 3338-3346.
-
(2007)
J Neurosci
, vol.27
, pp. 3338-3346
-
-
Periquet, M.1
Fulga, T.2
Myllykangas, L.3
Schlossmacher, M.G.4
Feany, M.B.5
-
56
-
-
0033178444
-
Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons
-
Stefanis L, Park DS, Friedman WJ, Greene LA (1999) Caspase-dependent and -independent death of camptothecin-treated embryonic cortical neurons. J Neurosci 19: 6235-6247.
-
(1999)
J Neurosci
, vol.19
, pp. 6235-6247
-
-
Stefanis, L.1
Park, D.S.2
Friedman, W.J.3
Greene, L.A.4
-
57
-
-
0142250840
-
Lack of p53 delays apoptosis, but increases ubiquitinated inclusions, in proteasomal inhibitor-treated cultured cortical neurons
-
Dietrich P, Rideout HJ, Wang Q, Stefanis L (2003) Lack of p53 delays apoptosis, but increases ubiquitinated inclusions, in proteasomal inhibitor-treated cultured cortical neurons. Mol Cell Neurosci 24: 430-441.
-
(2003)
Mol Cell Neurosci
, vol.24
, pp. 430-441
-
-
Dietrich, P.1
Rideout, H.J.2
Wang, Q.3
Stefanis, L.4
-
58
-
-
0036432029
-
Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination
-
Rideout HJ, Stefanis L (2002) Proteasomal inhibition-induced inclusion formation and death in cortical neurons require transcription and ubiquitination. Mol Cell Neurosci 21: 223-238.
-
(2002)
Mol Cell Neurosci
, vol.21
, pp. 223-238
-
-
Rideout, H.J.1
Stefanis, L.2
-
59
-
-
0032528153
-
Neuroprotective actions of dipyridamole on cultured CNS neurons
-
Farinelli SE, Greene LA, Friedman WJ (1998) Neuroprotective actions of dipyridamole on cultured CNS neurons. J Neurosci 18: 5112-5123.
-
(1998)
J Neurosci
, vol.18
, pp. 5112-5123
-
-
Farinelli, S.E.1
Greene, L.A.2
Friedman, W.J.3
-
60
-
-
0025939423
-
Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms
-
Rukenstein A, Rydel RE, Greene LA (1991) Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J Neurosci 11: 2552-2563.
-
(1991)
J Neurosci
, vol.11
, pp. 2552-2563
-
-
Rukenstein, A.1
Rydel, R.E.2
Greene, L.A.3
-
61
-
-
0030984171
-
Inhibitors of trypsin-like serine proteases inhibit processing of the caspase Nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support
-
Stefanis L, Troy CM, Qi H, Greene LA (1997) Inhibitors of trypsin-like serine proteases inhibit processing of the caspase Nedd-2 and protect PC12 cells and sympathetic neurons from death evoked by withdrawal of trophic support. J Neurochem 69: 1425-1437.
-
(1997)
J Neurochem
, vol.69
, pp. 1425-1437
-
-
Stefanis, L.1
Troy, C.M.2
Qi, H.3
Greene, L.A.4
-
62
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, et al. (1998) A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci U S A 95: 2509-2514.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
-
63
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, et al. (2001) Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411: 494-498.
-
(2001)
Nature
, vol.411
, pp. 494-498
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
-
64
-
-
1542336952
-
Rational siRNA design for RNA interference
-
Reynolds A, Leake D, Boese Q, Scaringe S, Marshall WS, et al. (2004) Rational siRNA design for RNA interference. Nat Biotechnol 22: 326-330.
-
(2004)
Nat Biotechnol
, vol.22
, pp. 326-330
-
-
Reynolds, A.1
Leake, D.2
Boese, Q.3
Scaringe, S.4
Marshall, W.S.5
|