-
1
-
-
0347357617
-
Protein folding and misfolding
-
DOI 10.1038/nature02261
-
Dobson C. M., Protein folding and misfolding Nature 2003 426 6968 884 890 (Pubitemid 38056880)
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 884-890
-
-
Dobson, C.M.1
-
2
-
-
70350150000
-
The emerging complexity of protein ubiquitination
-
Komander D., The emerging complexity of protein ubiquitination Biochemical Society Transactions 2009 37 5 937 953
-
(2009)
Biochemical Society Transactions
, vol.37
, Issue.5
, pp. 937-953
-
-
Komander, D.1
-
3
-
-
44649101850
-
Atypical ubiquitin chains: New molecular signals. 'Protein Modifications: Beyond the Usual Suspects' Review Series
-
DOI 10.1038/embor.2008.93, PII EMBOR200893
-
Ikeda F., Dikic I., Atypical ubiquitin chains: new molecular signals. protein modifications: beyond the usual suspects review series EMBO Reports 2008 9 6 536 542 (Pubitemid 351772916)
-
(2008)
EMBO Reports
, vol.9
, Issue.6
, pp. 536-542
-
-
Ikeda, F.1
Dikic, I.2
-
5
-
-
0021099710
-
Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown
-
Hershko A., Heller H., Elias S., Ciechanover A., Components of ubiquitin-protein ligase system. Resolution, affinity purification, and role in protein breakdown Journal of Biological Chemistry 1983 258 13 8206 8214
-
(1983)
Journal of Biological Chemistry
, vol.258
, Issue.13
, pp. 8206-8214
-
-
Hershko, A.1
Heller, H.2
Elias, S.3
Ciechanover, A.4
-
6
-
-
0034915764
-
Mechanisms underlying ubiquitination
-
DOI 10.1146/annurev.biochem.70.1.503
-
Pickart C. M., Mechanisms underlying ubiquitination Annual Review of Biochemistry 2001 70 503 533 (Pubitemid 32663902)
-
(2001)
Annual Review of Biochemistry
, vol.70
, pp. 503-533
-
-
Pickart, C.M.1
-
7
-
-
67349256160
-
Ubiquitin-like protein activation by E1 enzymes: The apex for downstream signalling pathways
-
Schulman B. A., Harper J. W., Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways Nature Reviews Molecular Cell Biology 2009 10 5 319 331
-
(2009)
Nature Reviews Molecular Cell Biology
, vol.10
, Issue.5
, pp. 319-331
-
-
Schulman, B.A.1
Harper, J.W.2
-
8
-
-
77951651753
-
The family of ubiquitin-conjugating enzymes (E2s): Deciding between life and death of proteins
-
Van Wijk S. J., Timmers H. T., The family of ubiquitin-conjugating enzymes (E2s): deciding between life and death of proteins The FASEB Journal 2010 24 4 981 993
-
(2010)
The FASEB Journal
, vol.24
, Issue.4
, pp. 981-993
-
-
Van Wijk, S.J.1
Timmers, H.T.2
-
9
-
-
77749341438
-
Ubiquitin ligase complexes: From substrate selectivity to conjugational specificity
-
Nagy V., Dikic I., Ubiquitin ligase complexes: from substrate selectivity to conjugational specificity Biological Chemistry 2010 391 2-3 163 169
-
(2010)
Biological Chemistry
, vol.391
, Issue.23
, pp. 163-169
-
-
Nagy, V.1
Dikic, I.2
-
10
-
-
65249098267
-
Catalytic mechanism and assembly of the proteasome
-
Marques A. J., Palanimurugan R., Mafias A. C., Ramos P. C., Dohmen R. J., Catalytic mechanism and assembly of the proteasome Chemical Reviews 2009 109 4 1509 1536
-
(2009)
Chemical Reviews
, vol.109
, Issue.4
, pp. 1509-1536
-
-
Marques, A.J.1
Palanimurugan, R.2
Mafias, A.C.3
Ramos, P.C.4
Dohmen, R.J.5
-
11
-
-
59249084491
-
The proteasome: Overview of structure and functions
-
Tanaka K., The proteasome: overview of structure and functions Proceedings of the Japan Academy B 2009 85 1 12 36
-
(2009)
Proceedings of the Japan Academy B
, vol.85
, Issue.1
, pp. 12-36
-
-
Tanaka, K.1
-
12
-
-
77955405539
-
Toward an integrated structural model of the 26S proteasome
-
Frster F., Lasker K., Nickell S., Sali A., Baumeister W., Toward an integrated structural model of the 26S proteasome Molecular and Cellular Proteomics 2010 9 8 1666 1677
-
(2010)
Molecular and Cellular Proteomics
, vol.9
, Issue.8
, pp. 1666-1677
-
-
Frster, F.1
Lasker, K.2
Nickell, S.3
Sali, A.4
Baumeister, W.5
-
13
-
-
65649115267
-
Recognition and processing of ubiquitin-protein conjugates by the proteasome
-
Finley D., Recognition and processing of ubiquitin-protein conjugates by the proteasome Annual Review of Biochemistry 2009 78 477 513
-
(2009)
Annual Review of Biochemistry
, vol.78
, pp. 477-513
-
-
Finley, D.1
-
14
-
-
36249025723
-
Autophagy: Process and function
-
DOI 10.1101/gad.1599207
-
Mizushima N., Autophagy: process and function Genes and Development 2007 21 22 2861 2873 (Pubitemid 350133435)
-
(2007)
Genes and Development
, vol.21
, Issue.22
, pp. 2861-2873
-
-
Mizushima, N.1
-
15
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
DOI 10.1038/nature06639, PII NATURE06639
-
Mizushima N., Levine B., Cuervo A. M., Klionsky D. J., Autophagy fights disease through cellular self-digestion Nature 2008 451 7182 1069 1075 (Pubitemid 351317450)
-
(2008)
Nature
, vol.451
, Issue.7182
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.M.3
Klionsky, D.J.4
-
16
-
-
67649467294
-
Dynamics and diversity in autophagy mechanisms: Lessons from yeast
-
Nakatogawa H., Suzuki K., Kamada Y., Ohsumi Y., Dynamics and diversity in autophagy mechanisms: lessons from yeast Nature Reviews Molecular Cell Biology 2009 10 7 458 467
-
(2009)
Nature Reviews Molecular Cell Biology
, vol.10
, Issue.7
, pp. 458-467
-
-
Nakatogawa, H.1
Suzuki, K.2
Kamada, Y.3
Ohsumi, Y.4
-
17
-
-
79959999581
-
Microautophagy in mammalian cells: Revisiting a 40-year-old conundrum
-
Mijaljica D., Prescott M., Devenish R. J., Microautophagy in mammalian cells: revisiting a 40-year-old conundrum Autophagy 2011 7 7 673 682
-
(2011)
Autophagy
, vol.7
, Issue.7
, pp. 673-682
-
-
Mijaljica, D.1
Prescott, M.2
Devenish, R.J.3
-
18
-
-
34250822281
-
Chaperone-mediated autophagy
-
Dice J. F., Chaperone-mediated autophagy Autophagy 2007 3 295 299 (Pubitemid 46986334)
-
(2007)
Autophagy
, vol.3
, Issue.4
, pp. 295-299
-
-
Dice, J.F.1
-
19
-
-
77950506157
-
Chaperone-mediated autophagy in health and disease
-
Kon M., Cuervo A. M., Chaperone-mediated autophagy in health and disease FEBS Letters 2010 584 7 1399 1404
-
(2010)
FEBS Letters
, vol.584
, Issue.7
, pp. 1399-1404
-
-
Kon, M.1
Cuervo, A.M.2
-
21
-
-
34848886914
-
Autophagosome formation: Core machinery and adaptations
-
DOI 10.1038/ncb1007-1102, PII NCB1007-1102
-
Xie Z., Klionsky D. J., Autophagosome formation: core machinery and adaptations Nature Cell Biology 2007 9 10 1102 1109 (Pubitemid 47500484)
-
(2007)
Nature Cell Biology
, vol.9
, Issue.10
, pp. 1102-1109
-
-
Xie, Z.1
Klionsky, D.J.2
-
22
-
-
79960878784
-
Atg8: An autophagy-related ubiquitin-like protein family
-
Shpilka T., Weidberg H., Pietrokovski S., Elazar Z., Atg8: an autophagy-related ubiquitin-like protein family Genome Biology 2011 12 7, article 226
-
(2011)
Genome Biology
, vol.12
, Issue.7 ARTICLE 226
-
-
Shpilka, T.1
Weidberg, H.2
Pietrokovski, S.3
Elazar, Z.4
-
23
-
-
34447099450
-
Atg8, a Ubiquitin-like Protein Required for Autophagosome Formation, Mediates Membrane Tethering and Hemifusion
-
DOI 10.1016/j.cell.2007.05.021, PII S0092867407006587
-
Nakatogawa H., Ichimura Y., Ohsumi Y., Atg8, a ubiquitin-like protein required for autophagosome formation, mediates membrane tethering and hemifusion Cell 2007 130 1 165 178 (Pubitemid 47031316)
-
(2007)
Cell
, vol.130
, Issue.1
, pp. 165-178
-
-
Nakatogawa, H.1
Ichimura, Y.2
Ohsumi, Y.3
-
24
-
-
3242888703
-
LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation
-
DOI 10.1242/jcs.01131
-
Kabeya Y., Mizushima N., Yamamoto A., Oshitani-Okamoto S., Ohsumi Y., Yoshimori T., LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation Journal of Cell Science 2004 117 13 2805 2812 (Pubitemid 38997262)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.13
, pp. 2805-2812
-
-
Kabeya, Y.1
Mizushima, N.2
Yamamoto, A.3
Oshitani-Okamoto, S.4
Ohsumi, Y.5
Yoshimori, T.6
-
25
-
-
77956410115
-
Selective autophagy: Ubiquitin-mediated recognition and beyond
-
Kraft C., Peter M., Hofmann K., Selective autophagy: ubiquitin-mediated recognition and beyond Nature Cell Biology 2010 12 9 836 841
-
(2010)
Nature Cell Biology
, vol.12
, Issue.9
, pp. 836-841
-
-
Kraft, C.1
Peter, M.2
Hofmann, K.3
-
26
-
-
79952355107
-
Selective autophagy mediated by autophagic adapter proteins
-
Johansen T., Lamark T., Selective autophagy mediated by autophagic adapter proteins Autophagy 2011 7 3 279 296
-
(2011)
Autophagy
, vol.7
, Issue.3
, pp. 279-296
-
-
Johansen, T.1
Lamark, T.2
-
27
-
-
65549142204
-
A Role for Ubiquitin in Selective Autophagy
-
Kirkin V., McEwan D. G., Novak I., Dikic I., A Role for Ubiquitin in Selective Autophagy Molecular Cell 2009 34 3 259 269
-
(2009)
Molecular Cell
, vol.34
, Issue.3
, pp. 259-269
-
-
Kirkin, V.1
McEwan, D.G.2
Novak, I.3
Dikic, I.4
-
28
-
-
27944504351
-
P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
DOI 10.1083/jcb.200507002
-
Bjrky G., Lamark T., Brech A., Outzen H., Perander M., vervatn A., Stenmark H., Johansen T., p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death Journal of Cell Biology 2005 171 4 603 614 (Pubitemid 41668720)
-
(2005)
Journal of Cell Biology
, vol.171
, Issue.4
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
29
-
-
53049103308
-
Structural basis for sorting mechanism of p62 in selective autophagy
-
Ichimura Y., Kumanomidou T., Sou Y. S., Mizushima T., Ezaki J., Ueno T., Kominami E., Yamane T., Tanaka K., Komatsu M., Structural basis for sorting mechanism of p62 in selective autophagy Journal of Biological Chemistry 2008 283 33 22847 22857
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.33
, pp. 22847-22857
-
-
Ichimura, Y.1
Kumanomidou, T.2
Sou, Y.S.3
Mizushima, T.4
Ezaki, J.5
Ueno, T.6
Kominami, E.7
Yamane, T.8
Tanaka, K.9
Komatsu, M.10
-
30
-
-
60849099049
-
A role for NBR1 in autophagosomal degradation of ubiquitinated substrates
-
Kirkin V., Lamark T., Sou Y. S., Bjrky G., Nunn J. L., Bruun J. A., Shvets E., McEwan D. G., Clausen T. H., Wild P., Bilusic I., Theurillat J. P., vervatn A., Ishii T., Elazar Z., Komatsu M., Dikic I., Johansen T., A role for NBR1 in autophagosomal degradation of ubiquitinated substrates Molecular Cell 2009 33 4 505 516
-
(2009)
Molecular Cell
, vol.33
, Issue.4
, pp. 505-516
-
-
Kirkin, V.1
Lamark, T.2
Sou, Y.S.3
Bjrky, G.4
Nunn, J.L.5
Bruun, J.A.6
Shvets, E.7
McEwan, D.G.8
Clausen, T.H.9
Wild, P.10
Bilusic, I.11
Theurillat, J.P.12
Vervatn, A.13
Ishii, T.14
Elazar, Z.15
Komatsu, M.16
Dikic, I.17
Johansen, T.18
-
31
-
-
34548259958
-
P62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy [S]
-
DOI 10.1074/jbc.M702824200
-
Pankiv S., Clausen T. H., Lamark T., Brech A., Bruun J. A., Outzen H., vervatn A., Bjrky G., Johansen T., p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy Journal of Biological Chemistry 2007 282 33 24131 24145 (Pubitemid 47328003)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.33
, pp. 24131-24145
-
-
Pankiv, S.1
Clausen, T.H.2
Lamark, T.3
Brech, A.4
Bruun, J.-A.5
Outzen, H.6
Overvatn, A.7
Bjorkoy, G.8
Johansen, T.9
-
33
-
-
7244236320
-
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death
-
DOI 10.1038/nature02998
-
Arrasate M., Mitra S., Schweitzer E. S., Segal M. R., Finkbeiner S., Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death Nature 2004 431 7010 805 810 (Pubitemid 39434070)
-
(2004)
Nature
, vol.431
, Issue.7010
, pp. 805-810
-
-
Arrasate, M.1
Mitra, S.2
Schweitzer, E.S.3
Segal, M.R.4
Finkbeiner, S.5
-
34
-
-
0034578389
-
Aggresomes, inclusion bodies and protein aggregation
-
Kopito R. R., Aggresomes, inclusion bodies and protein aggregation Trends in Cell Biology 2000 10 12 524 530
-
(2000)
Trends in Cell Biology
, vol.10
, Issue.12
, pp. 524-530
-
-
Kopito, R.R.1
-
35
-
-
0037551741
-
Protofibrils, pores, fibrils, and neurodegeneration: Separating the responsible protein aggregates from the innocent bystanders
-
DOI 10.1146/annurev.neuro.26.010302.081142
-
Caughey B., Lansbury P. T., Protofibrils, pores, fibrils, and neurodegeneration: separating the responsible protein aggregates from the innocent bystanders Annual Review of Neuroscience 2003 26 267 298 (Pubitemid 37064935)
-
(2003)
Annual Review of Neuroscience
, vol.26
, pp. 267-298
-
-
Caughey, B.1
Lansbury Jr., P.T.2
-
36
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
DOI 10.1146/annurev.biochem.75.101304.123901
-
Chiti F., Dobson C. M., Protein misfolding, functional amyloid, and human disease Annual Review of Biochemistry 2006 75 333 366 (Pubitemid 44118036)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
37
-
-
77949352928
-
Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation
-
Ortega Z., Daz-Hernndez M., Maynard C. J., Hernndez F., Dantuma N. P., Lucas J. J., Acute polyglutamine expression in inducible mouse model unravels ubiquitin/proteasome system impairment and permanent recovery attributable to aggregate formation Journal of Neuroscience 2010 30 10 3675 3688
-
(2010)
Journal of Neuroscience
, vol.30
, Issue.10
, pp. 3675-3688
-
-
Ortega, Z.1
Daz-Hernndez, M.2
Maynard, C.J.3
Hernndez, F.4
Dantuma, N.P.5
Lucas, J.J.6
-
38
-
-
80052830376
-
Chaperone-mediated hierarchical control in targeting misfolded proteins to aggresomes
-
Zhang X., Qian S. -B., Chaperone-mediated hierarchical control in targeting misfolded proteins to aggresomes Molecular Biology of the Cell 2011 22 18 3277 3288
-
(2011)
Molecular Biology of the Cell
, vol.22
, Issue.18
, pp. 3277-3288
-
-
Zhang, X.1
Qian, S.-B.2
-
39
-
-
33750363298
-
The roles of intracellular protein-degradation pathways in neurodegeneration
-
DOI 10.1038/nature05291, PII NATURE05291
-
Rubinsztein D. C., The roles of intracellular protein-degradation pathways in neurodegeneration Nature 2006 443 7113 780 786 (Pubitemid 44622682)
-
(2006)
Nature
, vol.443
, Issue.7113
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
40
-
-
78651282673
-
P62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
-
Itakura E., Mizushima N., p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding Journal of Cell Biology 2011 192 1 17 27
-
(2011)
Journal of Cell Biology
, vol.192
, Issue.1
, pp. 17-27
-
-
Itakura, E.1
Mizushima, N.2
-
41
-
-
34250828455
-
Proteomic analysis of membrane-associated proteins from rat liver autophagosomes
-
verbye A., Fengsrud M., Seglen P. O., Proteomic analysis of membrane-associated proteins from rat liver autophagosomes Autophagy 2007 3 4 300 322 (Pubitemid 46986335)
-
(2007)
Autophagy
, vol.3
, Issue.4
, pp. 300-322
-
-
Overbye, A.1
Fengsrud, M.2
Seglen, P.O.3
-
42
-
-
77952583297
-
Protein quality control in the ER: The recognition of misfolded proteins
-
Maattanen P., Gehring K., Bergeron J. J. M., Thomas D. Y., Protein quality control in the ER: the recognition of misfolded proteins Seminars in Cell and Developmental Biology 2010 21 5 500 511
-
(2010)
Seminars in Cell and Developmental Biology
, vol.21
, Issue.5
, pp. 500-511
-
-
Maattanen, P.1
Gehring, K.2
Bergeron, J.J.M.3
Thomas, D.Y.4
-
43
-
-
79959347089
-
A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation
-
Wang Q., Liu Y., Soetandyo N., Baek K., Hegde R., Ye Y., A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation Molecular Cell 2011 42 6 758 770
-
(2011)
Molecular Cell
, vol.42
, Issue.6
, pp. 758-770
-
-
Wang, Q.1
Liu, Y.2
Soetandyo, N.3
Baek, K.4
Hegde, R.5
Ye, Y.6
-
44
-
-
77950224150
-
Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage
-
Pratt W. B., Morishima Y., Peng H. M., Osawa Y., Proposal for a role of the Hsp90/Hsp70-based chaperone machinery in making triage decisions when proteins undergo oxidative and toxic damage Experimental Biology and Medicine 2010 235 3 278 289
-
(2010)
Experimental Biology and Medicine
, vol.235
, Issue.3
, pp. 278-289
-
-
Pratt, W.B.1
Morishima, Y.2
Peng, H.M.3
Osawa, Y.4
-
46
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
DOI 10.1038/nature05853, PII NATURE05853
-
Pandey U. B., Nie Z., Batlevi Y., McCray B. A., Ritson G. P., Nedelsky N. B., Schwartz S. L., Diprospero N. A., Knight M. A., Schuldiner O., Padmanabhan R., Hild M., Berry D. L., Garza D., Hubbert C. C., Yao T. P., Baehrecke E. H., Taylor J. P., HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS Nature 2007 447 7146 859 863 (Pubitemid 46920134)
-
(2007)
Nature
, vol.447
, Issue.7146
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
McCray, B.A.4
Ritson, G.P.5
Nedelsky, N.B.6
Schwartz, S.L.7
Diprospero, N.A.8
Knight, M.A.9
Schuldiner, O.10
Padmanabhan, R.11
Hild, M.12
Berry, D.L.13
Garza, D.14
Hubbert, C.C.15
Yao, T.-P.16
Baehrecke, E.H.17
Taylor, J.P.18
-
47
-
-
33645829816
-
Consequences of the selective blockage of chaperone-mediated autophagy
-
Massey A. C., Kaushik S., Sovak G., Kiffin R., Cuervo A. M., Consequences of the selective blockage of chaperone-mediated autophagy Proceedings of the National Academy of Sciences of the United States of America 2006 103 15 5805 5810
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.15
, pp. 5805-5810
-
-
Massey, A.C.1
Kaushik, S.2
Sovak, G.3
Kiffin, R.4
Cuervo, A.M.5
-
48
-
-
0038493550
-
Characterization of chronic low-level proteasome inhibition on neural homeostasis
-
DOI 10.1046/j.1471-4159.2003.01885.x
-
Ding Q., Dimayuga E., Martin S., Bruce-Keller A. J., Nukala V., Cuervo A. M., Keller J. N., Characterization of chronic low-level proteasome inhibition on neural homeostasis Journal of Neurochemistry 2003 86 2 489 497 (Pubitemid 36842448)
-
(2003)
Journal of Neurochemistry
, vol.86
, Issue.2
, pp. 489-497
-
-
Ding, Q.1
Dimayuga, E.2
Martin, S.3
Bruce-Keller, A.J.4
Nukala, V.5
Cuervo, A.M.6
Keller, J.N.7
-
49
-
-
24944482408
-
Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation
-
DOI 10.1073/pnas.0505801102
-
Iwata A., Christianson J. C., Bucci M., Ellerby L. M., Nukina N., Forno L. S., Kopito R. R., Increased susceptibility of cytoplasmic over nuclear polyglutamine aggregates to autophagic degradation Proceedings of the National Academy of Sciences of the United States of America 2005 102 37 13135 13140 (Pubitemid 41324991)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.37
, pp. 13135-13140
-
-
Iwata, A.1
Christianson, J.C.2
Bucci, M.3
Ellerby, L.M.4
Nukina, N.5
Forno, L.S.6
Kopito, R.R.7
-
50
-
-
48249091611
-
Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy
-
Kaushik S., Massey A. C., Mizushima N., Cuervo A. M., Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy Molecular Biology of the Cell 2008 19 5 2179 2192
-
(2008)
Molecular Biology of the Cell
, vol.19
, Issue.5
, pp. 2179-2192
-
-
Kaushik, S.1
Massey, A.C.2
Mizushima, N.3
Cuervo, A.M.4
-
51
-
-
70449927247
-
Autophagy is required to maintain muscle mass
-
Masiero E., Agatea L., Mammucari C., Blaauw B., Loro E., Komatsu M., Metzger D., Reggiani C., Schiaffino S., Sandri M., Autophagy is required to maintain muscle mass Cell Metabolism 2009 10 6 507 515
-
(2009)
Cell Metabolism
, vol.10
, Issue.6
, pp. 507-515
-
-
Masiero, E.1
Agatea, L.2
Mammucari, C.3
Blaauw, B.4
Loro, E.5
Komatsu, M.6
Metzger, D.7
Reggiani, C.8
Schiaffino, S.9
Sandri, M.10
-
52
-
-
57049094929
-
Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease
-
DOI 10.1093/hmg/ddn292
-
Raben N., Hill V., Shea L., Takikita S., Baum R., Mizushima N., Ralston E., Plotz P., Suppression of autophagy in skeletal muscle uncovers the accumulation of ubiquitinated proteins and their potential role in muscle damage in Pompe disease Human Molecular Genetics 2008 17 24 3897 3908 (Pubitemid 352762852)
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.24
, pp. 3897-3908
-
-
Raben, N.1
Hill, V.2
Shea, L.3
Takikita, S.4
Baum, R.5
Mizushima, N.6
Ralston, E.7
Plotz, P.8
-
53
-
-
33745192802
-
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
-
Hara T., Nakamura K., Matsui M., Yamamoto A., Nakahara Y., Suzuki-Migishima R., Yokoyama M., Mishima K., Saito I., Okano H., Mizushima N., Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice Nature 2006 441 7095 885 889
-
(2006)
Nature
, vol.441
, Issue.7095
, pp. 885-889
-
-
Hara, T.1
Nakamura, K.2
Matsui, M.3
Yamamoto, A.4
Nakahara, Y.5
Suzuki-Migishima, R.6
Yokoyama, M.7
Mishima, K.8
Saito, I.9
Okano, H.10
Mizushima, N.11
-
54
-
-
33646800306
-
Loss of autophagy in the central nervous system causes neurodegeneration in mice
-
Komatsu M., Waguri S., Chiba T., Murata S., Iwata J. I., Tanida I., Ueno T., Koike M., Uchiyama Y., Kominami E., Tanaka K., Loss of autophagy in the central nervous system causes neurodegeneration in mice Nature 2006 441 7095 880 884
-
(2006)
Nature
, vol.441
, Issue.7095
, pp. 880-884
-
-
Komatsu, M.1
Waguri, S.2
Chiba, T.3
Murata, S.4
Iwata, J.I.5
Tanida, I.6
Ueno, T.7
Koike, M.8
Uchiyama, Y.9
Kominami, E.10
Tanaka, K.11
-
55
-
-
36849089101
-
Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice
-
DOI 10.1016/j.cell.2007.10.035, PII S0092867407013542
-
Komatsu M., Waguri S., Koike M., Sou Y. S., Ueno T., Hara T., Mizushima N., Iwata J. I., Ezaki J., Murata S., Hamazaki J., Nishito Y., Iemura S. I., Natsume T., Yanagawa T., Uwayama J., Warabi E., Yoshida H., Ishii T., Kobayashi A., Yamamoto M., Yue Z., Uchiyama Y., Kominami E., Tanaka K., Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice Cell 2007 131 6 1149 1163 (Pubitemid 350235021)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1149-1163
-
-
Komatsu, M.1
Waguri, S.2
Koike, M.3
Sou, Y.-s.4
Ueno, T.5
Hara, T.6
Mizushima, N.7
Iwata, J.-i.8
Ezaki, J.9
Murata, S.10
Hamazaki, J.11
Nishito, Y.12
Iemura, S.-i.13
Natsume, T.14
Yanagawa, T.15
Uwayama, J.16
Warabi, E.17
Yoshida, H.18
Ishii, T.19
Kobayashi, A.20
Yamamoto, M.21
Yue, Z.22
Uchiyama, Y.23
Kominami, E.24
Tanaka, K.25
more..
-
56
-
-
0025294506
-
Peptide sequences that target cytosolic proteins for lysosomal proteolysis
-
Dice J. F., Peptide sequences that target cytosolic proteins for lysosomal proteolysis Trends in Biochemical Sciences 1990 15 8 305 309 (Pubitemid 20223216)
-
(1990)
Trends in Biochemical Sciences
, vol.15
, Issue.8
, pp. 305-309
-
-
Dice, J.F.1
-
57
-
-
6344275803
-
Activation of chaperone-mediated autophagy during oxidative stress
-
DOI 10.1091/mbc.E04-06-0477
-
Kiffin R., Christian C., Knecht E., Cuervo A. M., Activation of chaperone-mediated autophagy during oxidative stress Molecular Biology of the Cell 2004 15 11 4829 4840 (Pubitemid 39392200)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.11
, pp. 4829-4840
-
-
Kiffin, R.1
Christian, C.2
Knecht, E.3
Cuervo, A.M.4
-
58
-
-
0033013126
-
Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions
-
Ballinger C. A., Connell P., Wu Y., Hu Z., Thompson L. J., Yin L. Y., Patterson C., Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions Molecular and Cellular Biology 1999 19 6 4535 4545 (Pubitemid 29242026)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.6
, pp. 4535-4545
-
-
Ballinger, C.A.1
Connell, P.2
Wu, Y.3
Hu, Z.4
Thompson, L.J.5
Yin, L.-Y.6
Patterson, C.7
-
59
-
-
0035146685
-
The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins
-
DOI 10.1038/35050618
-
Connell P., Ballinger C. A., Jiang J., Wu Y., Thompson L. J., Hhfeld J., Patterson C., The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins Nature Cell Biology 2001 3 1 93 96 (Pubitemid 32114838)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.1
, pp. 93-96
-
-
Connell, P.1
Ballinger, C.A.2
Jiang, J.3
Wu, Y.4
Thompson, L.J.5
Hohfeld, J.6
Patterson, C.7
-
60
-
-
0035142877
-
The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation
-
DOI 10.1038/35050509
-
Meacham G. C., Patterson C., Zhang W., Younger J. M., Cyr D. M., The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation Nature Cell Biology 2001 3 1 100 105 (Pubitemid 32114840)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.1
, pp. 100-105
-
-
Meacham, G.C.1
Patterson, C.2
Zhang, W.3
Younger, J.M.4
Cyr, D.M.5
-
61
-
-
80051745465
-
Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP
-
Scaglione K. M., Zavodszky E., Todi S., Patury S., Xu P., Rodrguez-Lebrn E., Fischer S., Konen J., Djarmati A., Peng J., Gestwicki J., Paulson H., Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP Molecular Cell 2011 43 4 599 612
-
(2011)
Molecular Cell
, vol.43
, Issue.4
, pp. 599-612
-
-
Scaglione, K.M.1
Zavodszky, E.2
Todi, S.3
Patury, S.4
Xu, P.5
Rodrguez-Lebrn, E.6
Fischer, S.7
Konen, J.8
Djarmati, A.9
Peng, J.10
Gestwicki, J.11
Paulson, H.12
-
62
-
-
77952851112
-
Chaperone-assisted degradation: Multiple paths to destruction
-
Kettern N., Dreiseidler M., Tawo R., Hhfeld J., Chaperone-assisted degradation: multiple paths to destruction Biological Chemistry 2010 391 5 481 489
-
(2010)
Biological Chemistry
, vol.391
, Issue.5
, pp. 481-489
-
-
Kettern, N.1
Dreiseidler, M.2
Tawo, R.3
Hhfeld, J.4
-
63
-
-
38349105324
-
HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy
-
Carra S., Seguin S. J., Lambert H., Landry J., HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy Journal of Biological Chemistry 2008 283 3 1437 1444
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.3
, pp. 1437-1444
-
-
Carra, S.1
Seguin, S.J.2
Lambert, H.3
Landry, J.4
-
64
-
-
77955365630
-
The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS)
-
Crippa V., Sau D., Rusmini P., Boncoraglio A., Onesto E., Bolzoni E., Galbiati M., Fontana E., Marino M., Carra S., Bendotti C., de Biasi S., Poletti A., The small heat shock protein B8 (HspB8) promotes autophagic removal of misfolded proteins involved in amyotrophic lateral sclerosis (ALS) Human Molecular Genetics 2010 19 17 3440 3456
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.17
, pp. 3440-3456
-
-
Crippa, V.1
Sau, D.2
Rusmini, P.3
Boncoraglio, A.4
Onesto, E.5
Bolzoni, E.6
Galbiati, M.7
Fontana, E.8
Marino, M.9
Carra, S.10
Bendotti, C.11
De Biasi, S.12
Poletti, A.13
-
65
-
-
33748801507
-
BAG3 deficiency results in fulminant myopathy and early lethality
-
DOI 10.2353/ajpath.2006.060250
-
Homma S., Iwasaki M., Shelton G. D., Engvall E., Reed J. C., Takayama S., BAG3 deficiency results in fulminant myopathy and early lethality American Journal of Pathology 2006 169 3 761 773 (Pubitemid 44411944)
-
(2006)
American Journal of Pathology
, vol.169
, Issue.3
, pp. 761-773
-
-
Homma, S.1
Iwasaki, M.2
Shelton, G.D.3
Engvall, E.4
Reed, J.C.5
Takayama, S.6
-
66
-
-
74549133523
-
Chaperone-assisted selective autophagy is essential for muscle maintenance
-
Arndt V., Dick N., Tawo R., Dreiseidler M., Wenzel D., Hesse M., Furst D. O., Saftig P., Saint R., Fleischmann B. K., Hoch M., Hhfeld J., Chaperone-assisted selective autophagy is essential for muscle maintenance Current Biology 2010 20 2 143 148
-
(2010)
Current Biology
, vol.20
, Issue.2
, pp. 143-148
-
-
Arndt, V.1
Dick, N.2
Tawo, R.3
Dreiseidler, M.4
Wenzel, D.5
Hesse, M.6
Furst, D.O.7
Saftig, P.8
Saint, R.9
Fleischmann, B.K.10
Hoch, M.11
Hhfeld, J.12
-
67
-
-
60849131479
-
Mutation in BAG3 causes severe dominant childhood muscular dystrophy
-
Selcen D., Muntoni F., Burton B. K., Pegoraro E., Sewry C., Bite A. V., Engel A. G., Mutation in BAG3 causes severe dominant childhood muscular dystrophy Annals of Neurology 2009 65 1 83 89
-
(2009)
Annals of Neurology
, vol.65
, Issue.1
, pp. 83-89
-
-
Selcen, D.1
Muntoni, F.2
Burton, B.K.3
Pegoraro, E.4
Sewry, C.5
Bite, A.V.6
Engel, A.G.7
-
68
-
-
65449117176
-
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
-
Gamerdinger M., Hajieva P., Kaya A. M., Wolfrum U., Hartl F. U., Behl C., Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3 The EMBO Journal 2009 28 7 889 901
-
(2009)
The EMBO Journal
, vol.28
, Issue.7
, pp. 889-901
-
-
Gamerdinger, M.1
Hajieva, P.2
Kaya, A.M.3
Wolfrum, U.4
Hartl, F.U.5
Behl, C.6
-
69
-
-
1442358797
-
Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins
-
DOI 10.1083/jcb.200312073
-
Lelouard H., Ferrand V., Marguet D., Bania J., Camosseto V., David A., Gatti E., Pierre P., Dendritic cell aggresome-like induced structures are dedicated areas for ubiquitination and storage of newly synthesized defective proteins Journal of Cell Biology 2004 164 5 667 675 (Pubitemid 38282951)
-
(2004)
Journal of Cell Biology
, vol.164
, Issue.5
, pp. 667-675
-
-
Lelouard, H.1
Ferrand, V.2
Marguet, D.3
Bania, J.4
Camosseto, V.5
David, A.6
Gatti, E.7
Pierre, P.8
-
70
-
-
0037046536
-
Transient aggregation of ubiquitinated proteins during dendritic cell maturation
-
DOI 10.1038/417177a
-
Lelouard H., Gatti E., Cappello F., Gresser O., Camosseto V., Pierre P., Transient aggregation of ubiquitinated proteins during dendritic cell maturation Nature 2002 417 6885 177 182 (Pubitemid 34506798)
-
(2002)
Nature
, vol.417
, Issue.6885
, pp. 177-182
-
-
Lelouard, H.1
Gatti, E.2
Cappello, F.3
Gresser, O.4
Camosseto, V.5
Pierre, P.6
-
71
-
-
33745824614
-
ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy
-
Szeto J., Kaniuk N. A., Canadien V., Nisman R., Mizushima N., Yoshimori T., Bazett-Jones D. P., Brumell J. H., ALIS are stress-induced protein storage compartments for substrates of the proteasome and autophagy Autophagy 2006 2 3 189 199 (Pubitemid 44030883)
-
(2006)
Autophagy
, vol.2
, Issue.3
, pp. 189-199
-
-
Szeto, J.1
Kaniuk, N.A.2
Canadien, V.3
Nisman, R.4
Mizushima, N.5
Yoshimori, T.6
Bazett-Jones, D.P.7
Brumell, J.H.8
-
72
-
-
79251634318
-
The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells
-
Kettern N., Rogon C., Limmer A., Schild H., Hhfeld J., The Hsc/Hsp70 co-chaperone network controls antigen aggregation and presentation during maturation of professional antigen presenting cells Plos ONE 2011 6 1
-
(2011)
Plos ONE
, vol.6
, Issue.1
-
-
Kettern, N.1
Rogon, C.2
Limmer, A.3
Schild, H.4
Hhfeld, J.5
-
73
-
-
77249112669
-
Antigen processing via autophagy - Not only for MHC class II presentation anymore?
-
Munz C., Antigen processing via autophagy-not only for MHC class II presentation anymore? Current Opinion in Immunology 2010 22 1 89 93
-
(2010)
Current Opinion in Immunology
, vol.22
, Issue.1
, pp. 89-93
-
-
Munz, C.1
-
74
-
-
84859119158
-
Autophagy inhibition promotes defective neosynthesized proteins storage in ALIS, and induces redirection toward proteasome processing and MHCI-restricted presentation
-
Wenger T., Terawaki S., Camosseto V., Autophagy inhibition promotes defective neosynthesized proteins storage in ALIS, and induces redirection toward proteasome processing and MHCI-restricted presentation Autophagy 2012 8 3
-
(2012)
Autophagy
, vol.8
, Issue.3
-
-
Wenger, T.1
Terawaki, S.2
Camosseto, V.3
-
75
-
-
34047179973
-
Ubiquitinated-protein aggregates form in pancreatic β-cells during diabetes-induced oxidative stress and are regulated by autophagy
-
DOI 10.2337/db06-1160
-
Kaniuk N. A., Kiraly M., Bates H., Vranic M., Volchuk A., Brumell J. H., Ubiquitinated-protein aggregates form in pancreatic -cells during diabetes-induced oxidative stress and are regulated by autophagy Diabetes 2007 56 4 930 939 (Pubitemid 46525060)
-
(2007)
Diabetes
, vol.56
, Issue.4
, pp. 930-939
-
-
Kaniuk, N.A.1
Kiraly, M.2
Bates, H.3
Vranic, M.4
Volchuk, A.5
Brumell, J.H.6
-
76
-
-
0032576605
-
Aggresomes: A cellular response to misfolded proteins
-
DOI 10.1083/jcb.143.7.1883
-
Johnston J. A., Ward C. L., Kopito R. R., Aggresomes: a cellular response to misfolded proteins Journal of Cell Biology 1998 143 7 1883 1898 (Pubitemid 29022611)
-
(1998)
Journal of Cell Biology
, vol.143
, Issue.7
, pp. 1883-1898
-
-
Johnston, J.A.1
Ward, C.L.2
Kopito, R.R.3
-
77
-
-
0346020435
-
The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress
-
DOI 10.1016/S0092-8674(03)00939-5
-
Kawaguchi Y., Kovacs J. J., McLaurin A., Vance J. M., Ito A., Yao T. P., The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress Cell 2003 115 6 727 738 (Pubitemid 38030301)
-
(2003)
Cell
, vol.115
, Issue.6
, pp. 727-738
-
-
Kawaguchi, Y.1
Kovacs, J.J.2
McLaurin, A.3
Vance, J.M.4
Ito, A.5
Yao, T.-P.6
-
78
-
-
50649116818
-
Misfolded proteins partition between two distinct quality control compartments
-
Kaganovich D., Kopito R., Frydman J., Misfolded proteins partition between two distinct quality control compartments Nature 2008 454 7208 1088 1095
-
(2008)
Nature
, vol.454
, Issue.7208
, pp. 1088-1095
-
-
Kaganovich, D.1
Kopito, R.2
Frydman, J.3
-
79
-
-
77952914565
-
P62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
-
Clausen T. H., Lamark T., Isakson P., Finley K., Larsen K. B., Brech A., vervatn A., Stenmark H., Bjrky G., Simonsen A., Johansen T., p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy Autophagy 2010 6 3 330 344
-
(2010)
Autophagy
, vol.6
, Issue.3
, pp. 330-344
-
-
Clausen, T.H.1
Lamark, T.2
Isakson, P.3
Finley, K.4
Larsen, K.B.5
Brech, A.6
Vervatn, A.7
Stenmark, H.8
Bjrky, G.9
Simonsen, A.10
Johansen, T.11
-
80
-
-
77950903972
-
The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein alfy
-
Filimonenko M., Isakson P., Finley K. D., Anderson M., Jeong H., Melia T. J., Bartlett B. J., Myers K. M., Birkeland H. C. G., Lamark T., Krainc D., Brech A., Stenmark H., Simonsen A., Yamamoto A., The selective macroautophagic degradation of aggregated proteins requires the PI3P-binding protein alfy Molecular Cell 2010 38 2 265 279
-
(2010)
Molecular Cell
, vol.38
, Issue.2
, pp. 265-279
-
-
Filimonenko, M.1
Isakson, P.2
Finley, K.D.3
Anderson, M.4
Jeong, H.5
Melia, T.J.6
Bartlett, B.J.7
Myers, K.M.8
Birkeland, H.C.G.9
Lamark, T.10
Krainc, D.11
Brech, A.12
Stenmark, H.13
Simonsen, A.14
Yamamoto, A.15
-
81
-
-
77953139736
-
Fighting disease by selective autophagy of aggregate-prone proteins
-
Knvelsrud H., Simonsen A., Fighting disease by selective autophagy of aggregate-prone proteins FEBS Letters 2010 584 12 2635 2645
-
(2010)
FEBS Letters
, vol.584
, Issue.12
, pp. 2635-2645
-
-
Knvelsrud, H.1
Simonsen, A.2
-
82
-
-
28844475400
-
HDAC6 and microtubules are required for autophagic degradation of aggregated Huntingtin
-
DOI 10.1074/jbc.M508786200
-
Iwata A., Riley B. E., Johnston J. A., Kopito R. R., HDAC6 and microtubules are required for autophagic degradation of aggregated Huntingtin Journal of Biological Chemistry 2005 280 48 40282 40292 (Pubitemid 41779165)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.48
, pp. 40282-40292
-
-
Iwata, A.1
Riley, B.E.2
Johnston, J.A.3
Kopito, R.R.4
-
83
-
-
79952843826
-
The role of ubiquitin in autophagy-dependent protein aggregate processing
-
Yao T., The role of ubiquitin in autophagy-dependent protein aggregate processing Genes and Cancer 2010 1 7 779 786
-
(2010)
Genes and Cancer
, vol.1
, Issue.7
, pp. 779-786
-
-
Yao, T.1
-
84
-
-
41549114279
-
The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease
-
Pan T., Kondo S., Le W., Jankovic J., The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease Brain 2008 131 8 1969 1978
-
(2008)
Brain
, vol.131
, Issue.8
, pp. 1969-1978
-
-
Pan, T.1
Kondo, S.2
Le, W.3
Jankovic, J.4
-
85
-
-
34548851476
-
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6
-
DOI 10.1083/jcb.200611128
-
Olzmann J. A., Li A., Chudaev M. V., Chen J., Perez F. A., Palmiter R. D., Chin L. S., Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6 Journal of Cell Biology 2007 178 6 1025 1038 (Pubitemid 47443324)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.6
, pp. 1025-1038
-
-
Olzmann, J.A.1
Li, A.2
Chudaev, M.V.3
Chen, J.4
Perez, F.A.5
Palmiter, R.D.6
Chin, L.-S.7
-
86
-
-
77649337122
-
HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
-
Lee J. Y., Koga H., Kawaguchi Y., Tang W., Wong E., Gao Y. S., Pandey U. B., Kaushik S., Tresse E., Lu J., Taylor J. P., Cuervo A. M., Yao T. P., HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy The EMBO Journal 2010 29 5 969 980
-
(2010)
The EMBO Journal
, vol.29
, Issue.5
, pp. 969-980
-
-
Lee, J.Y.1
Koga, H.2
Kawaguchi, Y.3
Tang, W.4
Wong, E.5
Gao, Y.S.6
Pandey, U.B.7
Kaushik, S.8
Tresse, E.9
Lu, J.10
Taylor, J.P.11
Cuervo, A.M.12
Yao, T.P.13
-
87
-
-
79551609332
-
BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins
-
Gamerdinger M., Kaya A. M., Wolfrum U., Clement A. M., Behl C., BAG3 mediates chaperone-based aggresome-targeting and selective autophagy of misfolded proteins EMBO Reports 2011 12 2 149 156
-
(2011)
EMBO Reports
, vol.12
, Issue.2
, pp. 149-156
-
-
Gamerdinger, M.1
Kaya, A.M.2
Wolfrum, U.3
Clement, A.M.4
Behl, C.5
-
89
-
-
84855195340
-
Cdc48/p97, a key actor in the interplay between autophagy and ubiquitin/proteasome catabolic pathways
-
Dargemont C., Ossareh-Nazari B., Cdc48/p97, a key actor in the interplay between autophagy and ubiquitin/proteasome catabolic pathways Biochimica et Biophysica Acta 2012 1823 1 138 144
-
(2012)
Biochimica et Biophysica Acta
, vol.1823
, Issue.1
, pp. 138-144
-
-
Dargemont, C.1
Ossareh-Nazari, B.2
-
90
-
-
0742323006
-
Distinct Roles for the AAA ATPases NSF and p97 in the Secretory Pathway
-
DOI 10.1091/mbc.E03-02-0097
-
Dalal S., Rosser M. F. N., Cyr D. M., Hanson P. I., Distinct roles for the AAA ATPases NSF and p97 in the secretory pathway Molecular Biology of the Cell 2004 15 2 637 648 (Pubitemid 38146480)
-
(2004)
Molecular Biology of the Cell
, vol.15
, Issue.2
, pp. 637-648
-
-
Dalal, S.1
Rosser, M.F.N.2
Cyr, D.M.3
Hanson, P.I.4
-
91
-
-
33750528166
-
Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells
-
DOI 10.1091/mbc.E06-05-0432
-
Wjcik C., Rowicka M., Kudlicki A., Nowis D., McConnell E., Kujawa M., DeMartino G. N., Valosin-containing protein (p97) is a regulator of endoplasmic reticulum stress and of the degradation of N-end rule and ubiquitin-fusion degradation pathway substrates in mammalian cells Molecular Biology of the Cell 2006 17 11 4606 4618 (Pubitemid 44665732)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.11
, pp. 4606-4618
-
-
Wojcik, C.1
Rowicka, M.2
Kudlicki, A.3
Nowis, D.4
McConnell, E.5
Kujawa, M.6
DeMartino, G.N.7
-
92
-
-
18544394748
-
RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis
-
DOI 10.1242/jcs.00841
-
Wjcik C., Yano M., DeMartino G. N., RNA interference of valosin-containing protein (VCP/p97) reveals multiple cellular roles linked to ubiquitin/proteasome-dependent proteolysis Journal of Cell Science 2004 117 2 281 292 (Pubitemid 38128906)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.2
, pp. 281-292
-
-
Wojcik, C.1
Yano, M.2
DeMartino, G.N.3
-
93
-
-
33749257470
-
Going through the motions: The ATPase cycle of p97
-
DOI 10.1016/j.jsb.2006.03.003, PII S1047847706000736, AAA + Proteins
-
Pye V. E., Dreveny I., Briggs L. C., Sands C., Beuron F., Zhang X., Freemont P. S., Going through the motions: the ATPase cycle of p97 Journal of Structural Biology 2006 156 1 12 28 (Pubitemid 44486059)
-
(2006)
Journal of Structural Biology
, vol.156
, Issue.1
, pp. 12-28
-
-
Pye, V.E.1
Dreveny, I.2
Briggs, L.C.3
Sands, C.4
Beuron, F.5
Zhang, X.6
Freemont, P.S.7
-
94
-
-
0037084028
-
UFD1/NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates
-
DOI 10.1093/emboj/21.4.615
-
Braun S., Matuschewski K., Rape M., Thoms S., Jentsch S., Role of the ubiquitin-selective CDC48UFD1/NPL4 chaperone (segregase) in ERAD of OLE1 and other substrates The EMBO Journal 2002 21 4 615 621 (Pubitemid 34174042)
-
(2002)
EMBO Journal
, vol.21
, Issue.4
, pp. 615-621
-
-
Braun, S.1
Matuschewski, K.2
Rape, M.3
Thoms, S.4
Jentsch, S.5
-
95
-
-
37549068963
-
Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin
-
Ramadan K., Bruderer R., Spiga F. M., Popp O., Baur T., Gotta M., Meyer H. H., Cdc48/p97 promotes reformation of the nucleus by extracting the kinase Aurora B from chromatin Nature 2007 450 7173 1258 1262
-
(2007)
Nature
, vol.450
, Issue.7173
, pp. 1258-1262
-
-
Ramadan, K.1
Bruderer, R.2
Spiga, F.M.3
Popp, O.4
Baur, T.5
Gotta, M.6
Meyer, H.H.7
-
96
-
-
0035977095
-
UFD1/NPL4, a ubiquitin-selective chaperone
-
DOI 10.1016/S0092-8674(01)00595-5
-
Rape M., Hoppe T., Gorr I., Kalocay M., Richly H., Jentsch S., Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48UFD1/NPL4, a ubiquitin-selective chaperone Cell 2001 107 5 667 677 (Pubitemid 34014867)
-
(2001)
Cell
, vol.107
, Issue.5
, pp. 667-677
-
-
Rape, M.1
Hoppe, T.2
Gorr, I.3
Kalocay, M.4
Richly, H.5
Jentsch, S.6
-
97
-
-
80455164551
-
Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant -1 antitrypsin from the endoplasmic reticulum
-
Greenblatt E. J., Olzmann J. A., Kopito R. R., Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant -1 antitrypsin from the endoplasmic reticulum Nature Structural and Molecular Biology 2011 18 10 1147 1152
-
(2011)
Nature Structural and Molecular Biology
, vol.18
, Issue.10
, pp. 1147-1152
-
-
Greenblatt, E.J.1
Olzmann, J.A.2
Kopito, R.R.3
-
98
-
-
63649161943
-
The ubiquitylation machinery of the endoplasmic reticulum
-
Hirsch C., Gauss R., Horn S. C., Neuber O., Sommer T., The ubiquitylation machinery of the endoplasmic reticulum Nature 2009 458 7237 453 460
-
(2009)
Nature
, vol.458
, Issue.7237
, pp. 453-460
-
-
Hirsch, C.1
Gauss, R.2
Horn, S.C.3
Neuber, O.4
Sommer, T.5
-
99
-
-
78650729600
-
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
-
Tanaka A., Cleland M. M., Xu S., Narendra D. P., Suen D. F., Karbowski M., Youle R. J., Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin Journal of Cell Biology 2010 191 7 1367 1380
-
(2010)
Journal of Cell Biology
, vol.191
, Issue.7
, pp. 1367-1380
-
-
Tanaka, A.1
Cleland, M.M.2
Xu, S.3
Narendra, D.P.4
Suen, D.F.5
Karbowski, M.6
Youle, R.J.7
-
100
-
-
79551663809
-
The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover
-
Xu S., Peng G., Wang Y., Fang S., Karbowsk M., The AAA-ATPase p97 is essential for outer mitochondrial membrane protein turnover Molecular Biology of the Cell 2011 22 3 291 300
-
(2011)
Molecular Biology of the Cell
, vol.22
, Issue.3
, pp. 291-300
-
-
Xu, S.1
Peng, G.2
Wang, Y.3
Fang, S.4
Karbowsk, M.5
-
101
-
-
60549093730
-
Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates
-
Korolchuk V. I., Mansilla A., Menzies F. M., Rubinsztein D. C., Autophagy inhibition compromises degradation of ubiquitin-proteasome pathway substrates Molecular Cell 2009 33 4 517 527
-
(2009)
Molecular Cell
, vol.33
, Issue.4
, pp. 517-527
-
-
Korolchuk, V.I.1
Mansilla, A.2
Menzies, F.M.3
Rubinsztein, D.C.4
-
102
-
-
57649198447
-
Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease
-
Ju J. S., Miller S. E., Hanson P. I., Weihl C. C., Impaired protein aggregate handling and clearance underlie the pathogenesis of p97/VCP-associated disease Journal of Biological Chemistry 2008 283 44 30289 30299
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.44
, pp. 30289-30299
-
-
Ju, J.S.1
Miller, S.E.2
Hanson, P.I.3
Weihl, C.C.4
-
103
-
-
30644465041
-
Dominant-negative effect of mutant valosin-containing protein in aggresome formation
-
DOI 10.1016/j.febslet.2005.12.044, PII S001457930501519X
-
Kitami M. I., Kitami T., Nagahama M., Tagaya M., Hori S., Kakizuka A., Mizuno Y., Hattori N., Dominant-negative effect of mutant valosin-containing protein in aggresome formation FEBS Letters 2006 580 2 474 478 (Pubitemid 43089674)
-
(2006)
FEBS Letters
, vol.580
, Issue.2
, pp. 474-478
-
-
Kitami, M.-I.1
Kitami, T.2
Nagahama, M.3
Tagaya, M.4
Hori, S.5
Kakizuka, A.6
Mizuno, Y.7
Hattori, N.8
-
104
-
-
34250735508
-
Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates
-
DOI 10.1111/j.1365-2443.2007.01099.x
-
Kobayashi T., Manno A., Kakizuka A., Involvement of valosin-containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates Genes to Cells 2007 12 7 889 901 (Pubitemid 46965402)
-
(2007)
Genes to Cells
, vol.12
, Issue.7
, pp. 889-901
-
-
Kobayashi, T.1
Manno, A.2
Kakizuka, A.3
-
105
-
-
33746541576
-
HDAC6-p97/VCP controlled polyubiquitin chain turnover
-
DOI 10.1038/sj.emboj.7601210, PII 7601210
-
Boyault C., Gilquin B., Zhang Y., Rybin V., Garman E., Meyer-Klaucke W., Matthias P., Muller C. W., Khochbin S., HDAC6-p97/VCP controlled polyubiquitin chain turnover EMBO Journal 2006 25 14 3357 3366 (Pubitemid 44141793)
-
(2006)
EMBO Journal
, vol.25
, Issue.14
, pp. 3357-3366
-
-
Boyault, C.1
Gilquin, B.2
Zhang, Y.3
Rybin, V.4
Garman, E.5
Meyer-Klaucke, W.6
Matthias, P.7
Muller, C.W.8
Khochbin, S.9
-
106
-
-
77952533111
-
VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD
-
Tresse E., Salomons F. A., Vesa J., Bott L. C., Kimonis V., Yao T. P., Dantuma N. P., Taylor J. P., VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD Autophagy 2010 6 2 217 227
-
(2010)
Autophagy
, vol.6
, Issue.2
, pp. 217-227
-
-
Tresse, E.1
Salomons, F.A.2
Vesa, J.3
Bott, L.C.4
Kimonis, V.5
Yao, T.P.6
Dantuma, N.P.7
Taylor, J.P.8
-
107
-
-
77953894192
-
Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: A disorder of autophagy
-
Ju J. S., Weihl C. C., Inclusion body myopathy, Paget's disease of the bone and fronto-temporal dementia: a disorder of autophagy Human Molecular Genetics 2010 19 1 R38 R45
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.1
-
-
Ju, J.S.1
Weihl, C.C.2
-
108
-
-
77954957347
-
A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants
-
Tang W. K., Li D., Li C. C., Esser L., Dai R., Guo L., Xia D., A novel ATP-dependent conformation in p97 N-D1 fragment revealed by crystal structures of disease-related mutants The EMBO Journal 2010 29 13 2217 2229
-
(2010)
The EMBO Journal
, vol.29
, Issue.13
, pp. 2217-2229
-
-
Tang, W.K.1
Li, D.2
Li, C.C.3
Esser, L.4
Dai, R.5
Guo, L.6
Xia, D.7
-
109
-
-
77953121380
-
Imbalances in p97 co-factor interactions in human proteinopathy
-
Fernndez-Siz V., Buchberger A., Imbalances in p97 co-factor interactions in human proteinopathy EMBO Reports 2010 11 6 479 485
-
(2010)
EMBO Reports
, vol.11
, Issue.6
, pp. 479-485
-
-
Fernndez-Siz, V.1
Buchberger, A.2
-
110
-
-
31144470450
-
Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation
-
DOI 10.1093/hmg/ddi426
-
Weihl C. C., Dalal S., Pestronk A., Hanson P. I., Inclusion body myopathy-associated mutations in p97/VCP impair endoplasmic reticulum-associated degradation Human Molecular Genetics 2006 15 2 189 199 (Pubitemid 43125974)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.2
, pp. 189-199
-
-
Weihl, C.C.1
Dalal, S.2
Pestronk, A.3
Hanson, P.I.4
-
111
-
-
34447093377
-
Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice
-
DOI 10.1093/hmg/ddm037
-
Weihl C. C., Miller S. E., Hanson P. I., Pestronk A., Transgenic expression of inclusion body myopathy associated mutant p97/VCP causes weakness and ubiquitinated protein inclusions in mice Human Molecular Genetics 2007 16 8 919 928 (Pubitemid 47062736)
-
(2007)
Human Molecular Genetics
, vol.16
, Issue.8
, pp. 919-928
-
-
Weihl, C.C.1
Miller, S.E.2
Hanson, P.I.3
Pestronk, A.4
-
112
-
-
0036569345
-
From UBA to UBX: New words in the ubiquitin vocabulary
-
DOI 10.1016/S0962-8924(02)02269-9, PII S0962892402022699
-
Buchberger A., From UBA to UBX: new words in the ubiquitin vocabulary Trends in Cell Biology 2002 12 5 216 221 (Pubitemid 34327613)
-
(2002)
Trends in Cell Biology
, vol.12
, Issue.5
, pp. 216-221
-
-
Buchberger, A.1
-
113
-
-
0037065732
-
Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a
-
DOI 10.1021/bi011892y
-
Walters K. J., Kleijnen M. F., Goh A. M., Wagner G., Howley P. M., Structural studies of the interaction between ubiquitin family proteins and proteasome subunit S5a Biochemistry 2002 41 6 1767 1777 (Pubitemid 34132251)
-
(2002)
Biochemistry
, vol.41
, Issue.6
, pp. 1767-1777
-
-
Walters, K.J.1
Kleijnen, M.F.2
Goh, A.M.3
Wagner, G.4
Howley, P.M.5
-
114
-
-
70449723717
-
Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD
-
Lim P. J., Danner R., Liang J., Doong H., Harman C., Srinivasan D., Rothenberg C., Wang H., Ye Y., Fang S., Monteiro M. J., Ubiquilin and p97/VCP bind erasin, forming a complex involved in ERAD Journal of Cell Biology 2009 187 2 201 217
-
(2009)
Journal of Cell Biology
, vol.187
, Issue.2
, pp. 201-217
-
-
Lim, P.J.1
Danner, R.2
Liang, J.3
Doong, H.4
Harman, C.5
Srinivasan, D.6
Rothenberg, C.7
Wang, H.8
Ye, Y.9
Fang, S.10
Monteiro, M.J.11
-
115
-
-
77955023765
-
Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy
-
Rothenberg C., Srinivasan D., Mah L., Kaushik S., Peterhoff C. M., Ugolino J., Fang S., Cuervo A. M., Nixon R. A., Monteiro M. J., Ubiquilin functions in autophagy and is degraded by chaperone-mediated autophagy Human Molecular Genetics 2010 19 16 3219 3232
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.16
, pp. 3219-3232
-
-
Rothenberg, C.1
Srinivasan, D.2
Mah, L.3
Kaushik, S.4
Peterhoff, C.M.5
Ugolino, J.6
Fang, S.7
Cuervo, A.M.8
Nixon, R.A.9
Monteiro, M.J.10
-
116
-
-
33751514845
-
The UBL domain of PLIC-1 regulates aggresome formation
-
DOI 10.1038/sj.embor.7400823, PII 7400823
-
Heir R., Ablasou C., Dumontier E., Elliott M., Fagotto-Kaufmann C., Bedford F. K., The UBL domain of PLIC-1 regulates aggresome formation EMBO Reports 2006 7 12 1252 1258 (Pubitemid 44835094)
-
(2006)
EMBO Reports
, vol.7
, Issue.12
, pp. 1252-1258
-
-
Heir, R.1
Ablasou, C.2
Dumontier, E.3
Elliott, M.4
Fagotto-Kaufmann, C.5
Bedford, F.K.6
-
117
-
-
1842532263
-
Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins
-
Massey L. K., Mah A. L., Ford D. L., Miller J., Liang J., Doong H., Monteiro M. J., Overexpression of ubiquilin decreases ubiquitination and degradation of presenilin proteins Journal of Alzheimer's Disease 2004 6 1 79 92 (Pubitemid 38418560)
-
(2004)
Journal of Alzheimer's Disease
, vol.6
, Issue.1
, pp. 79-92
-
-
Massey, L.K.1
Mah, A.L.2
Ford, D.L.3
Miller, J.4
Liang, J.5
Doong, H.6
Monteiro, M.J.7
-
118
-
-
27644485567
-
Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction
-
DOI 10.1242/jcs.02571
-
Regan-Klapisz E., Sorokina I., Voortman J., de Keizer P., Rooves R. C., Verheesen P., Urbeé S., Fallon L., Fon E. A., Verkleij A., Benmerah A., van Bergen en Henegouwen P. M. P., Ubiquilin recruits Eps15 into ubiquitin-rich cytoplasmic aggregates via a UIM-UBL interaction Journal of Cell Science 2005 118 19 4437 4450 (Pubitemid 41556342)
-
(2005)
Journal of Cell Science
, vol.118
, Issue.19
, pp. 4437-4450
-
-
Regan-Klapisz, E.1
Sorokina, I.2
Voortman, J.3
De Keizer, P.4
Rooves, R.C.5
Verheesen, P.6
Urbee, S.7
Fallon, L.8
Fon, E.A.9
Verkleij, A.10
Benmerah, A.11
Van Bergenen Henegouwen, P.M.P.12
-
119
-
-
33644771265
-
Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin
-
DOI 10.1093/hmg/ddl017
-
Wang H., Lim P. J., Yin C., Rieckher M., Vogel B. E., Monteiro M. J., Suppression of polyglutamine-induced toxicity in cell and animal models of Huntington's disease by ubiquilin Human Molecular Genetics 2006 15 6 1025 1041 (Pubitemid 43338242)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.6
, pp. 1025-1041
-
-
Wang, H.1
Lim, P.J.2
Yin, C.3
Rieckher, M.4
Vogel, B.E.5
Monteiro, M.J.6
-
120
-
-
34447095637
-
Ubiquilin interacts and enhances the degradation of expanded- polyglutamine proteins
-
DOI 10.1016/j.bbrc.2007.06.097, PII S0006291X07013046
-
Wang H., Monteiro M. J., Ubiquilin interacts and enhances the degradation of expanded-polyglutamine proteins Biochemical and Biophysical Research Communications 2007 360 2 423 427 (Pubitemid 47030361)
-
(2007)
Biochemical and Biophysical Research Communications
, vol.360
, Issue.2
, pp. 423-427
-
-
Wang, H.1
Monteiro, M.J.2
-
121
-
-
66349128939
-
Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation
-
N'Diaye E. N., Debnath J., Brown E. J., Ubiquilins accelerate autophagosome maturation and promote cell survival during nutrient starvation Autophagy 2009 5 4 573 575
-
(2009)
Autophagy
, vol.5
, Issue.4
, pp. 573-575
-
-
N'Diaye, E.N.1
Debnath, J.2
Brown, E.J.3
-
122
-
-
59649110865
-
PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation
-
N'Diaye E. N., Kajihara K. K., Hsieh I., Morisaki H., Debnath J., Brown E. J., PLIC proteins or ubiquilins regulate autophagy-dependent cell survival during nutrient starvation EMBO Reports 2009 10 2 173 179
-
(2009)
EMBO Reports
, vol.10
, Issue.2
, pp. 173-179
-
-
N'Diaye, E.N.1
Kajihara, K.K.2
Hsieh, I.3
Morisaki, H.4
Debnath, J.5
Brown, E.J.6
-
123
-
-
80053927521
-
Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein
-
Stieren E. S., El Ayadi A., Xiao Y., Siller E., Landsverk M. L., Oberhauser A. F., Barral J. M., Boehning D., Ubiquilin-1 is a molecular chaperone for the amyloid precursor protein Journal of Biological Chemistry 2011 286 41 35689 35698
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.41
, pp. 35689-35698
-
-
Stieren, E.S.1
El Ayadi, A.2
Xiao, Y.3
Siller, E.4
Landsverk, M.L.5
Oberhauser, A.F.6
Barral, J.M.7
Boehning, D.8
-
124
-
-
0141445968
-
Interaction Codes within the Family of Mammalian Phox and Bem1p Domain-containing Proteins
-
DOI 10.1074/jbc.M303221200
-
Lamark T., Perander M., Outzen H., Kristiansen K., vervatn A., Michaelsen E., Bjrkoy G., Johansen T., Interaction codes within the family of mammalian phox and bem1p domain-containing proteins Journal of Biological Chemistry 2003 278 36 34568 34581 (Pubitemid 37553306)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.36
, pp. 34568-34581
-
-
Lamark, T.1
Perander, M.2
Outzen, H.3
Kristiansen, K.4
Overvatn, A.5
Michaelsen, E.6
BjOrkoy, G.7
Johansen, T.8
-
125
-
-
57249083972
-
Structural basis of target recognition by Atg8/LC3 during selective autophagy
-
Noda N. N., Kumeta H., Nakatogawa H., Satoo K., Adachi W., Ishii J., Fujioka Y., Ohsumi Y., Inagaki F., Structural basis of target recognition by Atg8/LC3 during selective autophagy Genes to Cells 2008 13 12 1211 1218
-
(2008)
Genes to Cells
, vol.13
, Issue.12
, pp. 1211-1218
-
-
Noda, N.N.1
Kumeta, H.2
Nakatogawa, H.3
Satoo, K.4
Adachi, W.5
Ishii, J.6
Fujioka, Y.7
Ohsumi, Y.8
Inagaki, F.9
-
126
-
-
79959498837
-
Characterization of the interaction of GABARAPL-1 with the LIR motif of NBR1
-
Rozenknop A., Rogov V. V., Rogova N. Y., Lhr F., Gntert P., Dikic I., Dtsch V., Characterization of the interaction of GABARAPL-1 with the LIR motif of NBR1 Journal of Molecular Biology 2011 410 3 477 487
-
(2011)
Journal of Molecular Biology
, vol.410
, Issue.3
, pp. 477-487
-
-
Rozenknop, A.1
Rogov, V.V.2
Rogova, N.Y.3
Lhr, F.4
Gntert, P.5
Dikic, I.6
Dtsch, V.7
-
127
-
-
77950484269
-
Atg8-family interacting motif crucial for selective autophagy
-
Noda N. N., Ohsumi Y., Inagaki F., Atg8-family interacting motif crucial for selective autophagy FEBS Letters 2010 584 7 1379 1385
-
(2010)
FEBS Letters
, vol.584
, Issue.7
, pp. 1379-1385
-
-
Noda, N.N.1
Ohsumi, Y.2
Inagaki, F.3
-
128
-
-
0041625934
-
PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62
-
DOI 10.1016/S1097-2765(03)00246-6
-
Wilson M. I., Gill D. J., Perisic O., Quinn M. T., Williams R. L., PB1 domain-mediated heterodimerization in NADPH oxidase and signaling complexes of atypical protein kinase C with Par6 and p62 Molecular Cell 2003 12 1 39 50 (Pubitemid 36957832)
-
(2003)
Molecular Cell
, vol.12
, Issue.1
, pp. 39-50
-
-
Wilson, M.I.1
Gill, D.J.2
Perisic, O.3
Quinn, M.T.4
Williams, R.L.5
-
129
-
-
80052363973
-
Plant NBR1 is a selective autophagy substrate and a functional hybrid of the mammalian autophagic adapters NBR1 and p62/SQSTM1
-
Svenning S., Lamark T., Krause K., Johansen T., Plant NBR1 is a selective autophagy substrate and a functional hybrid of the mammalian autophagic adapters NBR1 and p62/SQSTM1 Autophagy 2011 7 9 993 1010
-
(2011)
Autophagy
, vol.7
, Issue.9
, pp. 993-1010
-
-
Svenning, S.1
Lamark, T.2
Krause, K.3
Johansen, T.4
-
130
-
-
67650264633
-
Atg32 is a mitochondrial protein that confers selectivity during mitophagy
-
Kanki T., Wang K., Cao Y., Baba M., Klionsky D. J., Atg32 is a mitochondrial protein that confers selectivity during mitophagy Developmental Cell 2009 17 1 98 109
-
(2009)
Developmental Cell
, vol.17
, Issue.1
, pp. 98-109
-
-
Kanki, T.1
Wang, K.2
Cao, Y.3
Baba, M.4
Klionsky, D.J.5
-
131
-
-
67650246357
-
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy
-
Okamoto K., Kondo-Okamoto N., Ohsumi Y., Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy Developmental Cell 2009 17 1 87 97
-
(2009)
Developmental Cell
, vol.17
, Issue.1
, pp. 87-97
-
-
Okamoto, K.1
Kondo-Okamoto, N.2
Ohsumi, Y.3
-
132
-
-
74049153002
-
Nix is a selective autophagy receptor for mitochondrial clearance
-
Novak I., Kirkin V., McEwan D. G., Zhang J., Wild P., Rozenknop A., Rogov V., Lhr F., Popovic D., Occhipinti A., Reichert A. S., Terzic J., Dtsch V., Ney P. A., Dikic I., Nix is a selective autophagy receptor for mitochondrial clearance EMBO Reports 2010 11 1 45 51
-
(2010)
EMBO Reports
, vol.11
, Issue.1
, pp. 45-51
-
-
Novak, I.1
Kirkin, V.2
McEwan, D.G.3
Zhang, J.4
Wild, P.5
Rozenknop, A.6
Rogov, V.7
Lhr, F.8
Popovic, D.9
Occhipinti, A.10
Reichert, A.S.11
Terzic, J.12
Dtsch, V.13
Ney, P.A.14
Dikic, I.15
-
133
-
-
70350450808
-
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
-
Thurston T. L., Ryzhakov G., Bloor S., von Muhlinen N., Randow F., The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria Nature Immunology 2009 10 11 1215 1221
-
(2009)
Nature Immunology
, vol.10
, Issue.11
, pp. 1215-1221
-
-
Thurston, T.L.1
Ryzhakov, G.2
Bloor, S.3
Von Muhlinen, N.4
Randow, F.5
-
134
-
-
79960804104
-
Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth
-
Wild P., Farhan H., McEwan D. G., Wagner S., Rogov V. V., Brady N. R., Richter B., Korac J., Waidmann O., Choudhary C., Dtsch V., Bumann D., Dikic I., Phosphorylation of the autophagy receptor optineurin restricts Salmonella growth Science 2011 333 6039 228 233
-
(2011)
Science
, vol.333
, Issue.6039
, pp. 228-233
-
-
Wild, P.1
Farhan, H.2
McEwan, D.G.3
Wagner, S.4
Rogov, V.V.5
Brady, N.R.6
Richter, B.7
Korac, J.8
Waidmann, O.9
Choudhary, C.10
Dtsch, V.11
Bumann, D.12
Dikic, I.13
-
135
-
-
80053338210
-
Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: Identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1
-
Jiang S., Wells C. D., Roach P. J., Starch-binding domain-containing protein 1 (Stbd1) and glycogen metabolism: identification of the Atg8 family interacting motif (AIM) in Stbd1 required for interaction with GABARAPL1 Biochemical and Biophysical Research Communications 2011 413 3 420 425
-
(2011)
Biochemical and Biophysical Research Communications
, vol.413
, Issue.3
, pp. 420-425
-
-
Jiang, S.1
Wells, C.D.2
Roach, P.J.3
-
136
-
-
70350131893
-
Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism
-
Gal J., Strm A. L., Kwinter D. M., Kilty R., Zhang J., Shi P., Fu W., Wooten M. W., Zhu H., Sequestosome 1/p62 links familial ALS mutant SOD1 to LC3 via an ubiquitin-independent mechanism Journal of Neurochemistry 2009 111 4 1062 1073
-
(2009)
Journal of Neurochemistry
, vol.111
, Issue.4
, pp. 1062-1073
-
-
Gal, J.1
Strm, A.L.2
Kwinter, D.M.3
Kilty, R.4
Zhang, J.5
Shi, P.6
Fu, W.7
Wooten, M.W.8
Zhu, H.9
-
137
-
-
79961142199
-
P62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate
-
Watanabe Y., Tanaka M., p62/SQSTM1 in autophagic clearance of a non-ubiquitylated substrate Journal of Cell Science 2011 124 16 2692 2701
-
(2011)
Journal of Cell Science
, vol.124
, Issue.16
, pp. 2692-2701
-
-
Watanabe, Y.1
Tanaka, M.2
-
138
-
-
76249112828
-
Autophagy protects against sindbis virus infection of the central nervous system
-
Orvedahl A., MacPherson S., Sumpter R. Jr. , Tallczy Z., Zou Z., Levine B., Autophagy protects against sindbis virus infection of the central nervous system Cell Host and Microbe 2010 7 2 115 127
-
(2010)
Cell Host and Microbe
, vol.7
, Issue.2
, pp. 115-127
-
-
Orvedahl, A.1
MacPherson, S.2
Sumpter Jr., R.3
Tallczy, Z.4
Zou, Z.5
Levine, B.6
-
139
-
-
58249085224
-
SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans
-
Zhang Y., Yan L., Zhou Z., Yang P., Tian E., Zhang K., Zhao Y., Li Z., Song B., Han J., Miao L., Zhang H., SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans Cell 2009 136 2 308 321
-
(2009)
Cell
, vol.136
, Issue.2
, pp. 308-321
-
-
Zhang, Y.1
Yan, L.2
Zhou, Z.3
Yang, P.4
Tian, E.5
Zhang, K.6
Zhao, Y.7
Li, Z.8
Song, B.9
Han, J.10
Miao, L.11
Zhang, H.12
-
140
-
-
58549084167
-
Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes
-
Kim P. K., Hailey D. W., Mullen R. T., Lippincott-Schwartz J., Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes Proceedings of the National Academy of Sciences of the United States of America 2008 105 52 20567 20574
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.52
, pp. 20567-20574
-
-
Kim, P.K.1
Hailey, D.W.2
Mullen, R.T.3
Lippincott-Schwartz, J.4
-
141
-
-
58149344946
-
Midbody ring disposal by autophagy is a post-abscission event of cytokinesis
-
Pohl C., Jentsch S., Midbody ring disposal by autophagy is a post-abscission event of cytokinesis Nature Cell Biology 2009 11 1 65 70
-
(2009)
Nature Cell Biology
, vol.11
, Issue.1
, pp. 65-70
-
-
Pohl, C.1
Jentsch, S.2
-
142
-
-
80053564250
-
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity
-
Kuo T. C., Chen C. T., Baron D., Onder T. T., Loewer S., Almeida S., Weismann C. M., Xu P., Houghton J. M., Gao F. B., Daley G. Q., Doxsey S., Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity Nature Cell Biology 2011 13 10 1214 1223
-
(2011)
Nature Cell Biology
, vol.13
, Issue.10
, pp. 1214-1223
-
-
Kuo, T.C.1
Chen, C.T.2
Baron, D.3
Onder, T.T.4
Loewer, S.5
Almeida, S.6
Weismann, C.M.7
Xu, P.8
Houghton, J.M.9
Gao, F.B.10
Daley, G.Q.11
Doxsey, S.12
-
143
-
-
4944247868
-
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
-
DOI 10.1242/jcs.01287
-
Simonsen A., Birkeland H. C., Gillooly D. J., Mizushima N., Kuma A., Yoshimori T., Slagsvold T., Brech A., Stenmark H., Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes Journal of Cell Science 2004 117 18 4239 4251 (Pubitemid 39328311)
-
(2004)
Journal of Cell Science
, vol.117
, Issue.18
, pp. 4239-4251
-
-
Simonsen, A.1
Birkeland, H.C.G.2
Gillooly, D.J.3
Mizushima, N.4
Kuma, A.5
Yoshimori, T.6
Slagsvold, T.7
Brech, A.8
Stenmark, H.9
-
144
-
-
0037442507
-
Blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration
-
Finley K. D., Edeen P. T., Cumming R. C., Mardahl-Dumesnil M. D., Taylor B. J., Rodriguez M. H., Hwang C. E., Benedetti M., McKeown M., Blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration Journal of Neuroscience 2003 23 4 1254 1264 (Pubitemid 36258904)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.4
, pp. 1254-1264
-
-
Finley, K.D.1
Edeen, P.T.2
Cumming, R.C.3
Mardahl-Dumesnil, M.D.4
Taylor, B.J.5
Rodriguez, M.H.6
Hwang, C.E.7
Benedetti, M.8
McKeown, M.9
-
145
-
-
79955949858
-
The elimination of accumulated and aggregated proteins: A role for aggrephagy in neurodegeneration
-
Yamamoto A., Simonsen A., The elimination of accumulated and aggregated proteins: a role for aggrephagy in neurodegeneration Neurobiology of Disease 2011 43 1 17 28
-
(2011)
Neurobiology of Disease
, vol.43
, Issue.1
, pp. 17-28
-
-
Yamamoto, A.1
Simonsen, A.2
-
146
-
-
79953163464
-
The three musketeers of autophagy: Phosphorylation, ubiquitylation and acetylation
-
McEwan D. G., Dikic I., The three musketeers of autophagy: phosphorylation, ubiquitylation and acetylation Trends in Cell Biology 2011 21 4 195 201
-
(2011)
Trends in Cell Biology
, vol.21
, Issue.4
, pp. 195-201
-
-
McEwan, D.G.1
Dikic, I.2
-
147
-
-
38949162988
-
Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy
-
Tan J. M., Wong E. S., Dawson V. L., Dawson T. M., Lim K. L., Lysine 63-linked polyubiquitin potentially partners with p62 to promote the clearance of protein inclusions by autophagy Autophagy 2008 4 2 251 253 (Pubitemid 351231194)
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 251-253
-
-
Tan, J.M.M.1
Wong, E.S.P.2
Dawson, V.L.3
Dawson, T.M.4
Lim, K.-L.5
-
148
-
-
38349114036
-
Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases
-
Tan J. M., Wong E. S., Kirkpatrick D. S., Pletnikova O., Ko H. S., Tay S. P., Ho M. W. L., Troncoso J., Gygi S. P., Lee M. K., Dawson V. L., Dawson T. M., Lim K. L., Lysine 63-linked ubiquitination promotes the formation and autophagic clearance of protein inclusions associated with neurodegenerative diseases Human Molecular Genetics 2008 17 3 431 439
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.3
, pp. 431-439
-
-
Tan, J.M.1
Wong, E.S.2
Kirkpatrick, D.S.3
Pletnikova, O.4
Ko, H.S.5
Tay, S.P.6
Ho, M.W.L.7
Troncoso, J.8
Gygi, S.P.9
Lee, M.K.10
Dawson, V.L.11
Dawson, T.M.12
Lim, K.L.13
-
149
-
-
4444220680
-
Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation
-
DOI 10.1128/MCB.24.18.8055-8068.2004
-
Seibenhener M. L., Babu J. R., Geetha T., Wong H. C., Krishna N. R., Wooten M. W., Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation Molecular and Cellular Biology 2004 24 18 8055 8068 (Pubitemid 39167456)
-
(2004)
Molecular and Cellular Biology
, vol.24
, Issue.18
, pp. 8055-8068
-
-
Seibenhener, M.L.1
Babu, J.R.2
Geetha, T.3
Wong, H.C.4
Krishna, N.R.5
Wooten, M.W.6
-
150
-
-
33846692198
-
Signal integration and diversification through the p62 scaffold protein
-
DOI 10.1016/j.tibs.2006.12.002, PII S0968000406003276
-
Moscat J., Diaz-Meco M. T., Wooten M. W., Signal integration and diversification through the p62 scaffold protein Trends in Biochemical Sciences 2007 32 2 95 100 (Pubitemid 46199192)
-
(2007)
Trends in Biochemical Sciences
, vol.32
, Issue.2
, pp. 95-100
-
-
Moscat, J.1
Diaz-Meco, M.T.2
Wooten, M.W.3
-
152
-
-
55549086868
-
The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains
-
Winborn B. J., Travis S. M., Todi S. V., Scaglione K. M., Xu P., Williams A. J., Cohen R. E., Peng J., Paulson H. L., The deubiquitinating enzyme ataxin-3, a polyglutamine disease protein, edits Lys63 linkages in mixed linkage ubiquitin chains Journal of Biological Chemistry 2008 283 39 26436 26443
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.39
, pp. 26436-26443
-
-
Winborn, B.J.1
Travis, S.M.2
Todi, S.V.3
Scaglione, K.M.4
Xu, P.5
Williams, A.J.6
Cohen, R.E.7
Peng, J.8
Paulson, H.L.9
-
153
-
-
74249103961
-
Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3
-
Menzies F. M., Huebener J., Renna M., Bonin M., Riess O., Rubinsztein D. C., Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3 Brain 2010 133 1 93 104
-
(2010)
Brain
, vol.133
, Issue.1
, pp. 93-104
-
-
Menzies, F.M.1
Huebener, J.2
Renna, M.3
Bonin, M.4
Riess, O.5
Rubinsztein, D.C.6
-
154
-
-
42049100859
-
Essential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteins
-
Wooten M. W., Geetha T., Babu J. R., Seibenhener M. L., Peng J., Cox N., Diaz-Meco M. T., Moscat J., Essential role of sequestosome 1/p62 in regulating accumulation of Lys63-ubiquitinated proteins Journal of Biological Chemistry 2008 283 11 6783 6789
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.11
, pp. 6783-6789
-
-
Wooten, M.W.1
Geetha, T.2
Babu, J.R.3
Seibenhener, M.L.4
Peng, J.5
Cox, N.6
Diaz-Meco, M.T.7
Moscat, J.8
-
155
-
-
45249105920
-
Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration
-
DOI 10.1111/j.1471-4159.2008.05340.x
-
Ramesh Babu J., Lamar Seibenhener M., Peng J., Strom A. L., Kemppainen R., Cox N., Zhu H., Wooten M. C., Diaz-Meco M. T., Moscat J., Wooten M. W., Genetic inactivation of p62 leads to accumulation of hyperphosphorylated tau and neurodegeneration Journal of Neurochemistry 2008 106 1 107 120 (Pubitemid 351840194)
-
(2008)
Journal of Neurochemistry
, vol.106
, Issue.1
, pp. 107-120
-
-
Ramesh Babu, J.1
Lamar Seibenhener, M.2
Peng, J.3
Strom, A.-L.4
Kemppainen, R.5
Cox, N.6
Zhu, H.7
Wooten, M.C.8
Diaz-Meco, M.T.9
Moscat, J.10
Wooten, M.W.11
-
156
-
-
77956526505
-
TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains
-
Zucchelli S., Codrich M., Marcuzzi F., Pinto M., Vilotti S., Biagioli M., Ferrer I., Gustincich S., TRAF6 promotes atypical ubiquitination of mutant DJ-1 and alpha-synuclein and is localized to Lewy bodies in sporadic Parkinson's disease brains Human Molecular Genetics 2010 19 19 3759 3770
-
(2010)
Human Molecular Genetics
, vol.19
, Issue.19
, pp. 3759-3770
-
-
Zucchelli, S.1
Codrich, M.2
Marcuzzi, F.3
Pinto, M.4
Vilotti, S.5
Biagioli, M.6
Ferrer, I.7
Gustincich, S.8
-
157
-
-
77953858790
-
TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced Autophagy
-
Shi C. S., Kehrl J. H., TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced Autophagy Science Signaling 2010 3 123, article ra42
-
(2010)
Science Signaling
, vol.3
, Issue.123 ARTICLE RA42
-
-
Shi, C.S.1
Kehrl, J.H.2
-
158
-
-
77955875002
-
Regulation of the autophagy protein LC3 by phosphorylation
-
Cherra S. J. III, Kulich S. M., Uechi G., Balasubramani M., Mountzouris J., Day B. W., Chu C. T., Regulation of the autophagy protein LC3 by phosphorylation Journal of Cell Biology 2010 190 4 533 539
-
(2010)
Journal of Cell Biology
, vol.190
, Issue.4
, pp. 533-539
-
-
Cherra III, S.J.1
Kulich, S.M.2
Uechi, G.3
Balasubramani, M.4
Mountzouris, J.5
Day, B.W.6
Chu, C.T.7
-
159
-
-
82455172117
-
Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins
-
Matsumoto G., Wada K., Okuno M., Kurosawa M., Nukina N., Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins Molecular Cell 2011 44 2 279 289
-
(2011)
Molecular Cell
, vol.44
, Issue.2
, pp. 279-289
-
-
Matsumoto, G.1
Wada, K.2
Okuno, M.3
Kurosawa, M.4
Nukina, N.5
-
160
-
-
77952419246
-
Mutations of optineurin in amyotrophic lateral sclerosis
-
Maruyama H., Morino H., Ito H., Izumi Y., Kato H., Watanabe Y., Kinoshita Y., Kamada M., Nodera H., Suzuki H., Komure O., Matsuura S., Kobatake K., Morimoto N., Abe K., Suzuki N., Aoki M., Kawata A., Hirai T., Kato T., Ogasawara K., Hirano A., Takumi T., Kusaka H., Hagiwara K., Kaji R., Kawakami H., Mutations of optineurin in amyotrophic lateral sclerosis Nature 2010 465 7295 223 226
-
(2010)
Nature
, vol.465
, Issue.7295
, pp. 223-226
-
-
Maruyama, H.1
Morino, H.2
Ito, H.3
Izumi, Y.4
Kato, H.5
Watanabe, Y.6
Kinoshita, Y.7
Kamada, M.8
Nodera, H.9
Suzuki, H.10
Komure, O.11
Matsuura, S.12
Kobatake, K.13
Morimoto, N.14
Abe, K.15
Suzuki, N.16
Aoki, M.17
Kawata, A.18
Hirai, T.19
Kato, T.20
Ogasawara, K.21
Hirano, A.22
Takumi, T.23
Kusaka, H.24
Hagiwara, K.25
Kaji, R.26
Kawakami, H.27
more..
-
161
-
-
79960839810
-
Optineurin in neurodegenerative diseases
-
Osawa T., Mizuno Y., Fujita Y., Takatama M., Nakazato Y., Okamoto K., Optineurin in neurodegenerative diseases Neuropathology 2011 31 6 569 574
-
(2011)
Neuropathology
, vol.31
, Issue.6
, pp. 569-574
-
-
Osawa, T.1
Mizuno, Y.2
Fujita, Y.3
Takatama, M.4
Nakazato, Y.5
Okamoto, K.6
-
162
-
-
84855204007
-
Optineurin in Huntington's disease intranuclear inclusions
-
Schwab C., Yu S., McGeer E. G., McGeer P. L., Optineurin in Huntington's disease intranuclear inclusions Neuroscience Letters 2012 506 1 149 154
-
(2012)
Neuroscience Letters
, vol.506
, Issue.1
, pp. 149-154
-
-
Schwab, C.1
Yu, S.2
McGeer, E.G.3
McGeer, P.L.4
-
163
-
-
85066423771
-
Novel optineurin mutations in sporadic amyotrophic lateral sclerosis patients
-
In press
-
van Blitterswijk M., van Vught P. W., van Es M. A., Schelhaas H. J., van der Kooi A. J., de Visser M., Veldink J. H., van den Berg L. H., Novel optineurin mutations in sporadic amyotrophic lateral sclerosis patients. Neurobiology of Aging. In press
-
Neurobiology of Aging
-
-
Van Blitterswijk, M.1
Van Vught, P.W.2
Van Es, M.A.3
Schelhaas, H.J.4
Van Der Kooi, A.J.5
De Visser, M.6
Veldink, J.H.7
Van Den Berg, L.H.8
-
164
-
-
65249106104
-
Regulation of autophagy by the p300 acetyltransferase
-
Lee I. H., Finkel T., Regulation of autophagy by the p300 acetyltransferase Journal of Biological Chemistry 2009 284 10 6322 6328
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.10
, pp. 6322-6328
-
-
Lee, I.H.1
Finkel, T.2
-
165
-
-
63049132756
-
Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation
-
Jeong H., Then F., Melia T. J. Jr. , Mazzulli J. R., Cui L., Savas J. N., Voisine C., Paganetti P., Tanese N., Hart A. C., Yamamoto A., Krainc D., Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation Cell 2009 137 1 60 72
-
(2009)
Cell
, vol.137
, Issue.1
, pp. 60-72
-
-
Jeong, H.1
Then, F.2
Melia Jr., T.J.3
Mazzulli, J.R.4
Cui, L.5
Savas, J.N.6
Voisine, C.7
Paganetti, P.8
Tanese, N.9
Hart, A.C.10
Yamamoto, A.11
Krainc, D.12
-
166
-
-
72849148037
-
Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment
-
Mookerjee S., Papanikolaou T., Guyenet S. J., Sampath V., Lin A., Vitelli C., DeGiacomo F., Sopher B. L., Chen S. F., La Spada A. R., Ellerby L. M., Posttranslational modification of ataxin-7 at lysine 257 prevents autophagy-mediated turnover of an N-terminal caspase-7 cleavage fragment Journal of Neuroscience 2009 29 48 15134 15144
-
(2009)
Journal of Neuroscience
, vol.29
, Issue.48
, pp. 15134-15144
-
-
Mookerjee, S.1
Papanikolaou, T.2
Guyenet, S.J.3
Sampath, V.4
Lin, A.5
Vitelli, C.6
Degiacomo, F.7
Sopher, B.L.8
Chen, S.F.9
La Spada, A.R.10
Ellerby, L.M.11
-
167
-
-
77955352128
-
Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy
-
Fan W., Tang Z., Chen D., Moughon D., Ding X., Chen S., Zhu M., Zhong Q., Keap1 facilitates p62-mediated ubiquitin aggregate clearance via autophagy Autophagy 2010 6 5 614 621
-
(2010)
Autophagy
, vol.6
, Issue.5
, pp. 614-621
-
-
Fan, W.1
Tang, Z.2
Chen, D.3
Moughon, D.4
Ding, X.5
Chen, S.6
Zhu, M.7
Zhong, Q.8
-
168
-
-
77954599053
-
P62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription
-
Jain A., Lamark T., Sjttem E., Larsen K. B., Awuh J. A., vervatn A., McMahon M., Hayes J. D., Johansen T., p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription Journal of Biological Chemistry 2010 285 29 22576 22591
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.29
, pp. 22576-22591
-
-
Jain, A.1
Lamark, T.2
Sjttem, E.3
Larsen, K.B.4
Awuh, J.A.5
Vervatn, A.6
McMahon, M.7
Hayes, J.D.8
Johansen, T.9
-
169
-
-
77649265091
-
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
-
Komatsu M., Kurokawa H., Waguri S., Taguchi K., Kobayashi A., Ichimura Y., Sou Y. S., Ueno I., Sakamoto A., Tong K. I., Kim M., Nishito Y., Iemura S. I., Natsume T., Ueno T., Kominami E., Motohashi H., Tanaka K., Yamamoto M., The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1 Nature Cell Biology 2010 12 3 213 223
-
(2010)
Nature Cell Biology
, vol.12
, Issue.3
, pp. 213-223
-
-
Komatsu, M.1
Kurokawa, H.2
Waguri, S.3
Taguchi, K.4
Kobayashi, A.5
Ichimura, Y.6
Sou, Y.S.7
Ueno, I.8
Sakamoto, A.9
Tong, K.I.10
Kim, M.11
Nishito, Y.12
Iemura, S.I.13
Natsume, T.14
Ueno, T.15
Kominami, E.16
Motohashi, H.17
Tanaka, K.18
Yamamoto, M.19
-
170
-
-
77953366801
-
A noncanonical mechanism of Nrf2 activation by autophagy deficiency: Direct interaction between keap1 and p62
-
Lau A., Wang X. J., Zhao F., Villeneuve N. F., Wu T., Jiang T., Sun Z., White E., Zhang D. D., A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between keap1 and p62 Molecular and Cellular Biology 2010 30 13 3275 3285
-
(2010)
Molecular and Cellular Biology
, vol.30
, Issue.13
, pp. 3275-3285
-
-
Lau, A.1
Wang, X.J.2
Zhao, F.3
Villeneuve, N.F.4
Wu, T.5
Jiang, T.6
Sun, Z.7
White, E.8
Zhang, D.D.9
-
171
-
-
28844501852
-
Novel cytoprotective mechanism of anti-parkinsonian drug deprenyl: PI3K and Nrf2-derived induction of antioxidative proteins
-
DOI 10.1016/j.bbrc.2005.11.095, PII S0006291X05026070
-
Nakaso K., Nakamura C., Sato H., Imamura K., Takeshima T., Nakashima K., Novel cytoprotective mechanism of anti-parkinsonian drug deprenyl: PI3K and Nrf2-derived induction of antioxidative proteins Biochemical and Biophysical Research Communications 2006 339 3 915 922 (Pubitemid 41772899)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.339
, Issue.3
, pp. 915-922
-
-
Nakaso, K.1
Nakamura, C.2
Sato, H.3
Imamura, K.4
Takeshima, T.5
Nakashima, K.6
-
172
-
-
2442585133
-
Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: Possible mechanisms and the role in Lewy body formation in Parkinson's disease
-
DOI 10.1016/j.brainres.2004.03.029, PII S0006899304004743
-
Nakaso K., Yoshimoto Y., Nakano T., Takeshima T., Fukuhara Y., Yasui K., Araga S., Yanagawa T., Ishii T., Nakashima K., Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease Brain Research 2004 1012 1-2 42 51 (Pubitemid 38648897)
-
(2004)
Brain Research
, vol.1012
, Issue.1-2
, pp. 42-51
-
-
Nakaso, K.1
Yoshimoto, Y.2
Nakano, T.3
Takeshima, T.4
Fukuhara, Y.5
Yasui, K.6
Araga, S.7
Yanagawa, T.8
Ishii, T.9
Nakashima, K.10
-
173
-
-
77949324195
-
Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinated proteins to promyelocytic leukemia bodies
-
Pankiv S., Lamark T., Bruun J. A., vervatn A., Bjrky G., Johansen T., Nucleocytoplasmic shuttling of p62/SQSTM1 and its role in recruitment of nuclear polyubiquitinated proteins to promyelocytic leukemia bodies Journal of Biological Chemistry 2010 285 8 5941 5953
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.8
, pp. 5941-5953
-
-
Pankiv, S.1
Lamark, T.2
Bruun, J.A.3
Vervatn, A.4
Bjrky, G.5
Johansen, T.6
-
174
-
-
33749074277
-
Neuronal macroautophagy: From development to degeneration
-
DOI 10.1016/j.mam.2006.08.009, PII S0098299706000240
-
Boland B., Nixon R. A., Neuronal macroautophagy: from development to degeneration Molecular Aspects of Medicine 2006 27 5-6 503 519 (Pubitemid 44466657)
-
(2006)
Molecular Aspects of Medicine
, vol.27
, Issue.5-6
, pp. 503-519
-
-
Boland, B.1
Nixon, R.A.2
-
175
-
-
0036566266
-
Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy
-
Ravikumar B., Duden R., Rubinsztein D. C., Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy Human Molecular Genetics 2002 11 9 1107 1117 (Pubitemid 34521091)
-
(2002)
Human Molecular Genetics
, vol.11
, Issue.9
, pp. 1107-1117
-
-
Ravikumar, B.1
Duden, R.2
Rubinsztein, D.C.3
-
176
-
-
33644540193
-
Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway
-
Yamamoto A., Cremona M. L., Rothman J. E., Autophagy-mediated clearance of huntingtin aggregates triggered by the insulin-signaling pathway Journal of Cell Biology 2006 172 5 719 731
-
(2006)
Journal of Cell Biology
, vol.172
, Issue.5
, pp. 719-731
-
-
Yamamoto, A.1
Cremona, M.L.2
Rothman, J.E.3
-
177
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: Relationship to autophagic pathology in Alzheimer's disease
-
Boland B., Kumar A., Lee S., Platt F. M., Wegiel J., Yu W. H., Nixon R. A., Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease Journal of Neuroscience 2008 28 27 6926 6937
-
(2008)
Journal of Neuroscience
, vol.28
, Issue.27
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
Platt, F.M.4
Wegiel, J.5
Yu, W.H.6
Nixon, R.A.7
-
178
-
-
58149181486
-
Hsp104 and ClpB: Protein disaggregating machines
-
Doyle S. M., Wickner S., Hsp104 and ClpB: protein disaggregating machines Trends in Biochemical Sciences 2009 34 1 40 48
-
(2009)
Trends in Biochemical Sciences
, vol.34
, Issue.1
, pp. 40-48
-
-
Doyle, S.M.1
Wickner, S.2
-
179
-
-
80054699747
-
The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system
-
Shorter J., The mammalian disaggregase machinery: Hsp110 synergizes with Hsp70 and Hsp40 to catalyze protein disaggregation and reactivation in a cell-free system Plos ONE 2011 6 10
-
(2011)
Plos ONE
, vol.6
, Issue.10
-
-
Shorter, J.1
-
181
-
-
77954116814
-
Autophagy gone awry in neurodegenerative diseases
-
Wong E., Cuervo A. M., Autophagy gone awry in neurodegenerative diseases Nature Neuroscience 2010 13 7 805 811
-
(2010)
Nature Neuroscience
, vol.13
, Issue.7
, pp. 805-811
-
-
Wong, E.1
Cuervo, A.M.2
-
182
-
-
0034613294
-
Age-related decline in chaperone-mediated autophagy
-
Cuervo A. M., Dice J. F., Age-related decline in chaperone-mediated autophagy Journal of Biological Chemistry 2000 275 40 31505 31513
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.40
, pp. 31505-31513
-
-
Cuervo, A.M.1
Dice, J.F.2
-
183
-
-
33744916798
-
Regulation of intracellular accumulation of mutant huntingtin by beclin 1
-
DOI 10.1074/jbc.M600364200
-
Shibata M., Lu T., Furuya T., Degterev A., Mizushima N., Yoshimori T., MacDonald M., Yankner B., Yuan J., Regulation of intracellular accumulation of mutant huntingtin by beclin 1 Journal of Biological Chemistry 2006 281 20 14474 14485 (Pubitemid 43848378)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.20
, pp. 14474-14485
-
-
Shibata, M.1
Lu, T.2
Furuya, T.3
Degterev, A.4
Mizushima, N.5
Yoshimori, T.6
MacDonald, M.7
Yankner, B.8
Yuan, J.9
-
184
-
-
38949099761
-
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
-
Simonsen A., Cumming R. C., Brech A., Isakson P., Schubert D. R., Finley K. D., Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila Autophagy 2008 4 2 176 184 (Pubitemid 351231181)
-
(2008)
Autophagy
, vol.4
, Issue.2
, pp. 176-184
-
-
Simonsen, A.1
Cumming, R.C.2
Brech, A.3
Isakson, P.4
Schubert, D.R.5
Finley, K.D.6
-
185
-
-
2642586352
-
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
-
DOI 10.1038/ng1362
-
Ravikumar B., Vacher C., Berger Z., Davies J. E., Luo S., Oroz L. G., Scaravilli F., Easton D. F., Duden R., O'Kane C. J., Rubinsztein D. C., Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease Nature Genetics 2004 36 6 585 595 (Pubitemid 38715985)
-
(2004)
Nature Genetics
, vol.36
, Issue.6
, pp. 585-595
-
-
Ravikumar, B.1
Vacher, C.2
Berger, Z.3
Davies, J.E.4
Luo, S.5
Oroz, L.G.6
Scaravilli, F.7
Easton, D.F.8
Duden, R.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
186
-
-
0035919837
-
Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies
-
Kuusisto E., Salminen A., Alafuzoff I., Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies NeuroReport 2001 12 10 2085 2090 (Pubitemid 32646250)
-
(2001)
NeuroReport
, vol.12
, Issue.10
, pp. 2085-2090
-
-
Kuusisto, E.1
Salminen, A.2
Alafuzoff, I.3
-
187
-
-
37549066697
-
A block of autophagy in lysosomal storage disorders
-
Settembre C., Fraldi A., Jahreiss L., Spampanato C., Venturi C., Medina D., de Pablo R., Tacchetti C., Rubinsztein D. C., Ballabio A., A block of autophagy in lysosomal storage disorders Human Molecular Genetics 2008 17 1 119 129
-
(2008)
Human Molecular Genetics
, vol.17
, Issue.1
, pp. 119-129
-
-
Settembre, C.1
Fraldi, A.2
Jahreiss, L.3
Spampanato, C.4
Venturi, C.5
Medina, D.6
De Pablo, R.7
Tacchetti, C.8
Rubinsztein, D.C.9
Ballabio, A.10
-
188
-
-
56449086372
-
Mallory-Denk-bodies: Lessons from keratin-containing hepatic inclusion bodies
-
Strnad P., Zatloukal K., Stumptner C., Kulaksiz H., Denk H., Mallory-Denk-bodies: lessons from keratin-containing hepatic inclusion bodies Biochimica et Biophysica Acta 2008 1782 12 764 774
-
(2008)
Biochimica et Biophysica Acta
, vol.1782
, Issue.12
, pp. 764-774
-
-
Strnad, P.1
Zatloukal, K.2
Stumptner, C.3
Kulaksiz, H.4
Denk, H.5
-
189
-
-
0036144410
-
P62 is a common component of cytoplasmic inclusions in protein aggregation diseases
-
Zatloukal K., Stumptner C., Fuchsbichler A., Heid H., Schnoelzer M., Kenner L., Kleinert R., Prinz M., Aguzzi A., Denk H., p62 is a common component of cytoplasmic inclusions in protein aggregation diseases American Journal of Pathology 2002 160 1 255 263 (Pubitemid 34052286)
-
(2002)
American Journal of Pathology
, vol.160
, Issue.1
, pp. 255-263
-
-
Zatloukal, K.1
Stumptner, C.2
Fuchsbichler, A.3
Heid, H.4
Schnoelzer, M.5
Kenner, L.6
Kleinert, R.7
Prinz, M.8
Aguzzi, A.9
Denk, H.10
-
190
-
-
4744349602
-
Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions
-
DOI 10.1111/j.1471-4159.2004.02692.x
-
Nagaoka U., Kim K., Nihar R. J., Doi H., Maruyama M., Mitsui K., Oyama F., Nukina N., Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions Journal of Neurochemistry 2004 91 1 57 68 (Pubitemid 39314937)
-
(2004)
Journal of Neurochemistry
, vol.91
, Issue.1
, pp. 57-68
-
-
Nagaoka, U.1
Kim, K.2
Nihar, R.J.3
Doi, H.4
Maruyama, M.5
Mitsui, K.6
Oyama, F.7
Nukina, N.8
-
191
-
-
33645243056
-
Are the Mallory bodies and intracellular hyaline bodies in neoplastic and non-neoplastic hepatocytes related?
-
Denk H., Stumptner C., Fuchsbichler A., Are the Mallory bodies and intracellular hyaline bodies in neoplastic and non-neoplastic hepatocytes related? The Journal of Pathology 2006 208 5 653 661
-
(2006)
The Journal of Pathology
, vol.208
, Issue.5
, pp. 653-661
-
-
Denk, H.1
Stumptner, C.2
Fuchsbichler, A.3
-
192
-
-
77449094358
-
Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration
-
Liang C. C., Wang C., Peng X., Gan B., Guan J. L., Neural-specific deletion of FIP200 leads to cerebellar degeneration caused by increased neuronal death and axon degeneration Journal of Biological Chemistry 2010 285 5 3499 3509
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.5
, pp. 3499-3509
-
-
Liang, C.C.1
Wang, C.2
Peng, X.3
Gan, B.4
Guan, J.L.5
-
193
-
-
34249714158
-
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
-
DOI 10.1038/nm1574, PII NM1574
-
Nakai A., Yamaguchi O., Takeda T., Higuchi Y., Hikoso S., Taniike M., Omiya S., Mizote I., Matsumura Y., Asahi M., Nishida K., Hori M., Mizushima N., Otsu K., The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress Nature Medicine 2007 13 5 619 624 (Pubitemid 46828485)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 619-624
-
-
Nakai, A.1
Yamaguchi, O.2
Takeda, T.3
Higuchi, Y.4
Hikoso, S.5
Taniike, M.6
Omiya, S.7
Mizote, I.8
Matsumura, Y.9
Asahi, M.10
Nishida, K.11
Hori, M.12
Mizushima, N.13
Otsu, K.14
-
194
-
-
52749093177
-
Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet
-
Ebato C., Uchida T., Arakawa M., Komatsu M., Ueno T., Komiya K., Azuma K., Hirose T., Tanaka K., Kominami E., Kawamori R., Fujitani Y., Watada H., Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet Cell Metabolism 2008 8 4 325 332
-
(2008)
Cell Metabolism
, vol.8
, Issue.4
, pp. 325-332
-
-
Ebato, C.1
Uchida, T.2
Arakawa, M.3
Komatsu, M.4
Ueno, T.5
Komiya, K.6
Azuma, K.7
Hirose, T.8
Tanaka, K.9
Kominami, E.10
Kawamori, R.11
Fujitani, Y.12
Watada, H.13
-
195
-
-
52749094770
-
Loss of autophagy diminishes pancreatic cell mass and function with resultant hyperglycemia
-
Jung H. S., Chung K. W., Won Kim J., Kim J., Komatsu M., Tanaka K., Nguyen Y. H., Kang T. M., Yoon K. H., Kim J. W., Jeong Y. T., Han M. S., Lee M. K., Kim K. W., Shin J., Lee M. S., Loss of autophagy diminishes pancreatic cell mass and function with resultant hyperglycemia Cell Metabolism 2008 8 4 318 324
-
(2008)
Cell Metabolism
, vol.8
, Issue.4
, pp. 318-324
-
-
Jung, H.S.1
Chung, K.W.2
Won Kim, J.3
Kim, J.4
Komatsu, M.5
Tanaka, K.6
Nguyen, Y.H.7
Kang, T.M.8
Yoon, K.H.9
Kim, J.W.10
Jeong, Y.T.11
Han, M.S.12
Lee, M.K.13
Kim, K.W.14
Shin, J.15
Lee, M.S.16
-
196
-
-
77951169411
-
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
-
Hartleben B., Gdel M., Meyer-Schwesinger C., Liu S., Ulrich T., Kbler S., Wiech T., Grahammer F., Arnold S. J., Lindenmeyer M. T., Cohen C. D., Pavenstdt H., Kerjaschki D., Mizushima N., Shaw A. S., Walz G., Huber T. B., Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice Journal of Clinical Investigation 2010 120 4 1084 1096
-
(2010)
Journal of Clinical Investigation
, vol.120
, Issue.4
, pp. 1084-1096
-
-
Hartleben, B.1
Gdel, M.2
Meyer-Schwesinger, C.3
Liu, S.4
Ulrich, T.5
Kbler, S.6
Wiech, T.7
Grahammer, F.8
Arnold, S.J.9
Lindenmeyer, M.T.10
Cohen, C.D.11
Pavenstdt, H.12
Kerjaschki, D.13
Mizushima, N.14
Shaw, A.S.15
Walz, G.16
Huber, T.B.17
-
197
-
-
36849021043
-
Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila
-
DOI 10.1101/gad.1600707
-
Juhsz G., rdi B., Sass M., Neufeld T. P., Atg7-dependent autophagy promotes neuronal health, stress tolerance, and longevity but is dispensable for metamorphosis in Drosophila Genes and Development 2007 21 23 3061 3066 (Pubitemid 350223523)
-
(2007)
Genes and Development
, vol.21
, Issue.23
, pp. 3061-3066
-
-
Juhasz, G.1
Erdi, B.2
Sass, M.3
Neufeld, T.P.4
-
198
-
-
41549151641
-
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
-
DOI 10.1083/jcb.200711108
-
Nezis I. P., Simonsen A., Sagona A. P., Finley K., Gaumer S., Contamine D., Rusten T. E., Stenmark H., Brech A., Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain Journal of Cell Biology 2008 180 6 1065 1071 (Pubitemid 351468465)
-
(2008)
Journal of Cell Biology
, vol.180
, Issue.6
, pp. 1065-1071
-
-
Nezis, I.P.1
Simonsen, A.2
Sagona, A.P.3
Finley, K.4
Gaumer, S.5
Contamine, D.6
Rusten, T.E.7
Stenmark, H.8
Brech, A.9
-
199
-
-
82355175806
-
Abnormalities of NBR1, a novel autophagy-associated protein, in muscle fibers of sporadic inclusion-body myositis
-
D'Agostino C., Nogalska A., Cacciottolo M., King Engel W., Askanas V., Abnormalities of NBR1, a novel autophagy-associated protein, in muscle fibers of sporadic inclusion-body myositis Acta Neuropathologica 2011 122 5 627 636
-
(2011)
Acta Neuropathologica
, vol.122
, Issue.5
, pp. 627-636
-
-
D'Agostino, C.1
Nogalska, A.2
Cacciottolo, M.3
King Engel, W.4
Askanas, V.5
-
200
-
-
68349097450
-
P62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis
-
Nogalska A., Terracciano C., D'Agostino C., King Engel W., Askanas V., p62/SQSTM1 is overexpressed and prominently accumulated in inclusions of sporadic inclusion-body myositis muscle fibers, and can help differentiating it from polymyositis and dermatomyositis Acta Neuropathologica 2009 118 3 407 413
-
(2009)
Acta Neuropathologica
, vol.118
, Issue.3
, pp. 407-413
-
-
Nogalska, A.1
Terracciano, C.2
D'Agostino, C.3
King Engel, W.4
Askanas, V.5
-
202
-
-
0032568534
-
α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
-
DOI 10.1073/pnas.95.11.6469
-
Spillantini M. G., Crowther R. A., Jakes R., Hasegawa M., Goedert M., -Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies Proceedings of the National Academy of Sciences of the United States of America 1998 95 11 6469 6473 (Pubitemid 28249037)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
203
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D., Tanaka A., Suen D. F., Youle R. J., Parkin is recruited selectively to impaired mitochondria and promotes their autophagy Journal of Cell Biology 2008 183 5 795 803
-
(2008)
Journal of Cell Biology
, vol.183
, Issue.5
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
204
-
-
0242531029
-
Inhibition of Proteasomal Activity Causes Inclusion Formation in Neuronal and Non-Neuronal Cells Overexpressing Parkin
-
DOI 10.1091/mbc.E03-02-0078
-
Ardley H. C., Scott G. B., Rose S. A., Tan N. G. S., Markham A. F., Robinson P. A., Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing parkin Molecular Biology of the Cell 2003 14 11 4541 4556 (Pubitemid 37444654)
-
(2003)
Molecular Biology of the Cell
, vol.14
, Issue.11
, pp. 4541-4556
-
-
Ardley, H.C.1
Scott, G.B.2
Rose, S.A.3
Tan, N.G.S.4
Markham, A.F.5
Robinson, P.A.6
-
205
-
-
3142540683
-
Lewy-body formation is an aggresome-related process: A hypothesis
-
DOI 10.1016/S1474-4422(04)00827-0, PII S1474442204008270
-
Olanow C. W., Perl D. P., DeMartino G. N., McNaught K. S. P., Lewy-body formation is an aggresome-related process: a hypothesis Lancet Neurology 2004 3 8 496 503 (Pubitemid 38903101)
-
(2004)
Lancet Neurology
, vol.3
, Issue.8
, pp. 496-503
-
-
Olanow, C.W.1
Perl, D.P.2
DeMartino, G.N.3
McNaught, K.St.P.4
-
206
-
-
1042266326
-
Aggresomes Formed by α-Synuclein and Synphilin-1 Are Cytoprotective
-
DOI 10.1074/jbc.M310994200
-
Tanaka M., Kim Y. M., Lee G., Junn E., Iwatsubo T., Mouradian M. M., Aggresomes formed by -synuclein and synphilin-1 are cytoprotective Journal of Biological Chemistry 2004 279 6 4625 4631 (Pubitemid 38199054)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.6
, pp. 4625-4631
-
-
Tanaka, M.1
Kim, Y.M.2
Lee, G.3
Junn, E.4
Iwatsubo, T.5
Mouradian, M.M.6
-
207
-
-
4344659685
-
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
-
DOI 10.1126/science.1101738
-
Cuervo A. M., Stafanis L., Fredenburg R., Lansbury P. T., Sulzer D., Impaired degradation of mutant -synuclein by chaperone-mediated autophagy Science 2004 305 5688 1292 1295 (Pubitemid 39129234)
-
(2004)
Science
, vol.305
, Issue.5688
, pp. 1292-1295
-
-
Cuervo, A.M.1
Stafanis, L.2
Fredenburg, R.3
Lansbury, P.T.4
Sulzer, D.5
-
208
-
-
1442275729
-
Clearance of α-Synuclein Oligomeric Intermediates via the Lysosomal Degradation Pathway
-
DOI 10.1523/JNEUROSCI.3809-03.2004
-
Lee H. J., Khoshaghideh F., Patel S., Lee S. J., Clearance of -synuclein oligomeric intermediates via the lysosomal degradation pathway Journal of Neuroscience 2004 24 8 1888 1896 (Pubitemid 38292800)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.8
, pp. 1888-1896
-
-
Lee, H.-J.1
Khoshaghideh, F.2
Patel, S.3
Lee, S.-J.4
-
209
-
-
0041589248
-
α-synuclein Is Degraded by Both Autophagy and the Proteasome
-
DOI 10.1074/jbc.M300227200
-
Webb J. L., Ravikumar B., Atkins J., Skepper J. N., Rubinsztein D. C., -synuclein is degraded by both autophagy and the proteasome Journal of Biological Chemistry 2003 278 27 25009 25013 (Pubitemid 37548663)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.27
, pp. 25009-25013
-
-
Webb, J.L.1
Ravikumar, B.2
Atkins, J.3
Skepper, J.N.4
Rubinsztein, D.C.5
-
210
-
-
38849174979
-
Dopamine-modified α-synuclein blocks chaperone-mediated autophagy
-
DOI 10.1172/JCI32806
-
Martinez-Vicente M., Talloczy Z., Kaushik S., Massey A. C., Mazzulli J., Mosharov E. V., Hodara R., Fredenburg R., Wu D. -C., Follenzi A., Dauer W., Przedborski S., Ischiropoulos H., Lansbury P. T., Sulzer D., Cuervo A. M., Dopamine-modified -synuclein blocks chaperone-mediated autophagy Journal of Clinical Investigation 2008 118 2 777 778 (Pubitemid 351206565)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.2
, pp. 777-778
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Kaushik, S.3
Massey, A.C.4
Mazzulli, J.5
Mosharov, E.V.6
Hodara, R.7
Fredenburg, R.8
Wu, D.-C.9
Follenzi, A.10
Dauer, W.11
Przedborski, S.12
Ischiropoulos, H.13
Lansbury, P.T.14
Sulzer, D.15
Cuervo, A.M.16
-
211
-
-
70349987102
-
Tau fragmentation, aggregation and clearance: The dual role of lysosomal processing
-
Wang Y., Martinez-Vicente M., Kruger U., Kaushik S., Wong E., Mandelkow E. M., Cuervo A. M., Mandelkow E., Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing Human Molecular Genetics 2009 18 21 4153 4170
-
(2009)
Human Molecular Genetics
, vol.18
, Issue.21
, pp. 4153-4170
-
-
Wang, Y.1
Martinez-Vicente, M.2
Kruger, U.3
Kaushik, S.4
Wong, E.5
Mandelkow, E.M.6
Cuervo, A.M.7
Mandelkow, E.8
-
212
-
-
77949504405
-
Selective molecular alterations in the autophagy pathway in patients with lewy body disease and in models of -synucleinopathy
-
Crews L., Spencer B., Desplats P., Patrick C., Paulino A., Rockenstein E., Hansen L., Adame A., Galasko D., Masliah E., Selective molecular alterations in the autophagy pathway in patients with lewy body disease and in models of -synucleinopathy Plos ONE 2010 5 2
-
(2010)
Plos ONE
, vol.5
, Issue.2
-
-
Crews, L.1
Spencer, B.2
Desplats, P.3
Patrick, C.4
Paulino, A.5
Rockenstein, E.6
Hansen, L.7
Adame, A.8
Galasko, D.9
Masliah, E.10
-
213
-
-
70350550208
-
Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in -synuclein models of Parkinson's and Lewy body diseases
-
Spencer B., Potkar R., Trejo M., Rockenstein E., Patrick C., Gindi R., Adame A., Wyss-Coray T., Masliah E., Beclin 1 gene transfer activates autophagy and ameliorates the neurodegenerative pathology in -synuclein models of Parkinson's and Lewy body diseases Journal of Neuroscience 2009 29 43 13578 13588
-
(2009)
Journal of Neuroscience
, vol.29
, Issue.43
, pp. 13578-13588
-
-
Spencer, B.1
Potkar, R.2
Trejo, M.3
Rockenstein, E.4
Patrick, C.5
Gindi, R.6
Adame, A.7
Wyss-Coray, T.8
Masliah, E.9
-
214
-
-
68449089023
-
Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric -synuclein
-
Yu W. H., Dorado B., Figueroa H. Y., Wang L., Planel E., Cookson M. R., Clark L. N., Duff K. E., Metabolic activity determines efficacy of macroautophagic clearance of pathological oligomeric -synuclein American Journal of Pathology 2009 175 2 736 747
-
(2009)
American Journal of Pathology
, vol.175
, Issue.2
, pp. 736-747
-
-
Yu, W.H.1
Dorado, B.2
Figueroa, H.Y.3
Wang, L.4
Planel, E.5
Cookson, M.R.6
Clark, L.N.7
Duff, K.E.8
-
215
-
-
31544454404
-
Rapamycin alleviates toxicity of different aggregate-prone proteins
-
DOI 10.1093/hmg/ddi458
-
Berger Z., Ravikumar B., Menzies F. M., Oroz L. G., Underwood B. R., Pangalos M. N., Schmitt I., Wullner U., Evert B. O., O'Kane C. J., Rubinsztein D. C., Rapamycin alleviates toxicity of different aggregate-prone proteins Human Molecular Genetics 2006 15 3 433 442 (Pubitemid 43159895)
-
(2006)
Human Molecular Genetics
, vol.15
, Issue.3
, pp. 433-442
-
-
Berger, Z.1
Ravikumar, B.2
Menzies, F.M.3
Oroz, L.G.4
Underwood, B.R.5
Pangalos, M.N.6
Schmitt, I.7
Wullner, U.8
Evert, B.O.9
O'Kane, C.J.10
Rubinsztein, D.C.11
-
216
-
-
42249106042
-
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway
-
DOI 10.1038/nchembio.79, PII NCHEMBIO79
-
Williams A., Sarkar S., Cuddon P., Ttofi E. K., Saiki S., Siddiqi F. H., Jahreiss L., Fleming A., Pask D., Goldsmith P., O'Kane C. J., Floto R. A., Rubinsztein D. C., Novel targets for Huntington's disease in an mTOR-independent autophagy pathway Nature Chemical Biology 2008 4 5 295 305 (Pubitemid 351550888)
-
(2008)
Nature Chemical Biology
, vol.4
, Issue.5
, pp. 295-305
-
-
Williams, A.1
Sarkar, S.2
Cuddon, P.3
Ttofi, E.K.4
Saiki, S.5
Siddiqi, F.H.6
Jahreiss, L.7
Fleming, A.8
Pask, D.9
Goldsmith, P.10
O'Kane, C.J.11
Floto, R.A.12
Rubinsztein, D.C.13
-
217
-
-
77956757594
-
Neurodegeneration by polyglutamine Atrophin is not rescued by induction of autophagy
-
Nisoli I., Chauvin J. P., Napoletano F., Calamita P., Zanin V., Fanto M., Charroux B., Neurodegeneration by polyglutamine Atrophin is not rescued by induction of autophagy Cell Death and Differentiation 2010 17 10 1577 1587
-
(2010)
Cell Death and Differentiation
, vol.17
, Issue.10
, pp. 1577-1587
-
-
Nisoli, I.1
Chauvin, J.P.2
Napoletano, F.3
Calamita, P.4
Zanin, V.5
Fanto, M.6
Charroux, B.7
-
218
-
-
77951665859
-
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
-
Martinez-Vicente M., Talloczy Z., Wong E., Tang G., Koga H., Kaushik S., De Vries R., Arias E., Harris S., Sulzer D., Cuervo A. M., Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease Nature Neuroscience 2010 13 5 567 576
-
(2010)
Nature Neuroscience
, vol.13
, Issue.5
, pp. 567-576
-
-
Martinez-Vicente, M.1
Talloczy, Z.2
Wong, E.3
Tang, G.4
Koga, H.5
Kaushik, S.6
De Vries, R.7
Arias, E.8
Harris, S.9
Sulzer, D.10
Cuervo, A.M.11
-
219
-
-
61649085621
-
Tau pathophysiology in neurodegeneration: A tangled issue
-
Spires-Jones T. L., Stoothoff W. H., de Calignon A., Jones P. B., Hyman B. T., Tau pathophysiology in neurodegeneration: a tangled issue Trends in Neurosciences 2009 32 3 150 159
-
(2009)
Trends in Neurosciences
, vol.32
, Issue.3
, pp. 150-159
-
-
Spires-Jones, T.L.1
Stoothoff, W.H.2
De Calignon, A.3
Jones, P.B.4
Hyman, B.T.5
-
220
-
-
0035958642
-
Tauopathy in Drosophila: Neurodegeneration without neurofibrillary tangles
-
Wittmann C. W., Wszolek M. F., Shulman J. M., Salvaterra P. M., Lewis J., Hutton M., Feany M. B., Tauopathy in Drosophila: neurodegeneration without neurofibrillary tangles Science 2001 293 5530 711 714 (Pubitemid 32728676)
-
(2001)
Science
, vol.293
, Issue.5530
, pp. 711-714
-
-
Wittmann, C.W.1
Wszolek, M.F.2
Shulman, J.M.3
Salvaterra, P.M.4
Lewis, J.5
Hutton, M.6
Feany, M.B.7
-
221
-
-
80053243942
-
Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits
-
Majumder S., Richardson A., Strong R., Oddo S., Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits Plos ONE 2011 6 9
-
(2011)
Plos ONE
, vol.6
, Issue.9
-
-
Majumder, S.1
Richardson, A.2
Strong, R.3
Oddo, S.4
-
222
-
-
79960951303
-
Proteasome inhibition drives HDAC6-dependent recruitment of tau to aggresomes
-
Guthrie C. R., Kraemer B. C., Proteasome inhibition drives HDAC6-dependent recruitment of tau to aggresomes Journal of Molecular Neuroscience 2011 45 1 32 41
-
(2011)
Journal of Molecular Neuroscience
, vol.45
, Issue.1
, pp. 32-41
-
-
Guthrie, C.R.1
Kraemer, B.C.2
-
223
-
-
49549083278
-
Histone deacetylase 6 interacts with the microtubule-associated protein tau
-
Ding H., Dolan P. J., Johnson G. V. W., Histone deacetylase 6 interacts with the microtubule-associated protein tau Journal of Neurochemistry 2008 106 5 2119 2130
-
(2008)
Journal of Neurochemistry
, vol.106
, Issue.5
, pp. 2119-2130
-
-
Ding, H.1
Dolan, P.J.2
Johnson, G.V.W.3
-
224
-
-
82055164435
-
Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions
-
Miki Y., Mori F., Tanji K., Kakita A., Takahashi H., Wakabayashi K., Accumulation of histone deacetylase 6, an aggresome-related protein, is specific to Lewy bodies and glial cytoplasmic inclusions Neuropathology 2011 31 6 561 568
-
(2011)
Neuropathology
, vol.31
, Issue.6
, pp. 561-568
-
-
Miki, Y.1
Mori, F.2
Tanji, K.3
Kakita, A.4
Takahashi, H.5
Wakabayashi, K.6
-
225
-
-
65949122957
-
Tauan inhibitor of deacetylase HDAC6 function
-
Perez M., Santa-Maria I., de Barreda E. G., Zhu X., Cuadros R., Cabrero J. R., Sanchez-Madrid F., Dawson H. N., Vitek M. P., Perry G., Smith M. A., Avila J., Tauan inhibitor of deacetylase HDAC6 function Journal of Neurochemistry 2009 109 6 1756 1766
-
(2009)
Journal of Neurochemistry
, vol.109
, Issue.6
, pp. 1756-1766
-
-
Perez, M.1
Santa-Maria, I.2
De Barreda, E.G.3
Zhu, X.4
Cuadros, R.5
Cabrero, J.R.6
Sanchez-Madrid, F.7
Dawson, H.N.8
Vitek, M.P.9
Perry, G.10
Smith, M.A.11
Avila, J.12
-
226
-
-
40749161986
-
Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally
-
Zhang Y., Kwon S., Yamaguchi T., Cubizolles F., Rousseaux S., Kneissel M., Cao C., Li N., Cheng H. L., Chua K., Lombard D., Mizeracki A., Matthias G., Alt F. W., Khochbin S., Matthias P., Mice lacking histone deacetylase 6 have hyperacetylated tubulin but are viable and develop normally Molecular and Cellular Biology 2008 28 5 1688 1701
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.5
, pp. 1688-1701
-
-
Zhang, Y.1
Kwon, S.2
Yamaguchi, T.3
Cubizolles, F.4
Rousseaux, S.5
Kneissel, M.6
Cao, C.7
Li, N.8
Cheng, H.L.9
Chua, K.10
Lombard, D.11
Mizeracki, A.12
Matthias, G.13
Alt, F.W.14
Khochbin, S.15
Matthias, P.16
-
227
-
-
33846815066
-
TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations
-
DOI 10.1097/nen.0b013e31803020b9, PII 0000507220070200000007
-
Neumann M., Mackenzie I. R., Cairns N. J., Boyer P. J., Markesbery W. R., Smith C. D., Taylor J. P., Kretzschmar H. A., Kimonis V. E., Forman M. S., TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations Journal of Neuropathology and Experimental Neurology 2007 66 2 152 157 (Pubitemid 46208736)
-
(2007)
Journal of Neuropathology and Experimental Neurology
, vol.66
, Issue.2
, pp. 152-157
-
-
Neumann, M.1
Mackenzie, I.R.2
Cairns, N.J.3
Boyer, P.J.4
Markesbery, W.R.5
Smith, C.D.6
Taylor, J.P.7
Kretzschmar, H.A.8
Kimonis, V.E.9
Forman, M.S.10
-
228
-
-
77953194507
-
TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97
-
Ritson G. P., Custer S. K., Freibaum B. D., Guinto J. B., Geffel D., Moore J., Tang W., Winton M. J., Neumann M., Trojanowski J. Q., Lee V. M. Y., Forman M. S., Taylor J. P., TDP-43 mediates degeneration in a novel Drosophila model of disease caused by mutations in VCP/p97 Journal of Neuroscience 2010 30 22 7729 7739
-
(2010)
Journal of Neuroscience
, vol.30
, Issue.22
, pp. 7729-7739
-
-
Ritson, G.P.1
Custer, S.K.2
Freibaum, B.D.3
Guinto, J.B.4
Geffel, D.5
Moore, J.6
Tang, W.7
Winton, M.J.8
Neumann, M.9
Trojanowski, J.Q.10
Lee, V.M.Y.11
Forman, M.S.12
Taylor, J.P.13
-
229
-
-
75649135319
-
Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6
-
Fiesel F. C., Voigt A., Weber S. S., Van den Haute C., Waldenmaier A., Grner K., Walter M., Anderson M. L., Kern J. V., Rasse T. M., Schmidt T., Springer W., Kirchner R., Bonin M., Neumann M., Baekelandt V., Alunni-Fabbroni M., Schulz J. B., Kahle P. J., Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6 The EMBO Journal 2010 29 1 209 221
-
(2010)
The EMBO Journal
, vol.29
, Issue.1
, pp. 209-221
-
-
Fiesel, F.C.1
Voigt, A.2
Weber, S.S.3
Van Den Haute, C.4
Waldenmaier, A.5
Grner, K.6
Walter, M.7
Anderson, M.L.8
Kern, J.V.9
Rasse, T.M.10
Schmidt, T.11
Springer, W.12
Kirchner, R.13
Bonin, M.14
Neumann, M.15
Baekelandt, V.16
Alunni-Fabbroni, M.17
Schulz, J.B.18
Kahle, P.J.19
-
230
-
-
84455169931
-
Regulation of autophagy by neuropathological protein TDP-43
-
Bose J. K., Huang C. C., Shen C. K., Regulation of autophagy by neuropathological protein TDP-43 Journal of Biological Chemistry 2011 286 52 44441 44448
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.52
, pp. 44441-44448
-
-
Bose, J.K.1
Huang, C.C.2
Shen, C.K.3
-
231
-
-
78649941297
-
Exome sequencing reveals VCP mutations as a cause of familial ALS
-
Johnson J. O., Mandrioli J., Benatar M., Abramzon Y., Van Deerlin V. M., Trojanowski J. Q., Gibbs J. R., Brunetti M., Gronka S., Wuu J., Ding J., McCluskey L., Martinez-Lage M., Falcone D., Hernandez D. G., Arepalli S., Chong S., Schymick J. C., Rothstein J., Landi F., Wang Y. D., Calvo A., Mora G., Sabatelli M., Monsurr M. R., Battistini S., Salvi F., Spataro R., Sola P., Borghero G., Galassi G., Scholz S. W., Taylor J. P., Restagno G., Chi A., Traynor B. J., Exome sequencing reveals VCP mutations as a cause of familial ALS Neuron 2010 68 5 857 864
-
(2010)
Neuron
, vol.68
, Issue.5
, pp. 857-864
-
-
Johnson, J.O.1
Mandrioli, J.2
Benatar, M.3
Abramzon, Y.4
Van Deerlin, V.M.5
Trojanowski, J.Q.6
Gibbs, J.R.7
Brunetti, M.8
Gronka, S.9
Wuu, J.10
Ding, J.11
McCluskey, L.12
Martinez-Lage, M.13
Falcone, D.14
Hernandez, D.G.15
Arepalli, S.16
Chong, S.17
Schymick, J.C.18
Rothstein, J.19
Landi, F.20
Wang, Y.D.21
Calvo, A.22
Mora, G.23
Sabatelli, M.24
Monsurr, M.R.25
Battistini, S.26
Salvi, F.27
Spataro, R.28
Sola, P.29
Borghero, G.30
Galassi, G.31
Scholz, S.W.32
Taylor, J.P.33
Restagno, G.34
Chi, A.35
Traynor, B.J.36
more..
-
232
-
-
80855150639
-
SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis
-
Fecto F., Yan J., Vemula S. P., Liu E., Yang Y., Chen W., Zheng J. G., Shi Y., Siddique N., Arrat H., Donkervoort S., Ajroud-Driss S., Sufit R. L., Heller S. L., Deng H. -X., Siddique T., SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis Archives of Neurology 2011 68 11 1440 1446
-
(2011)
Archives of Neurology
, vol.68
, Issue.11
, pp. 1440-1446
-
-
Fecto, F.1
Yan, J.2
Vemula, S.P.3
Liu, E.4
Yang, Y.5
Chen, W.6
Zheng, J.G.7
Shi, Y.8
Siddique, N.9
Arrat, H.10
Donkervoort, S.11
Ajroud-Driss, S.12
Sufit, R.L.13
Heller, S.L.14
Deng, H.-X.15
Siddique, T.16
-
233
-
-
80053603907
-
Unravelling the twists and turns of the serpinopathies
-
Roussel B. D., Irving J. A., Ekeowa U. I., Belorgey D., Haq I., Ordez A., Kruppa A. J., Duvoix A., Rashid S. T., Crowther D. C., Marciniak S. J., Lomas D. A., Unravelling the twists and turns of the serpinopathies The FEBS Journal 2011 278 20 3859 3867
-
(2011)
The FEBS Journal
, vol.278
, Issue.20
, pp. 3859-3867
-
-
Roussel, B.D.1
Irving, J.A.2
Ekeowa, U.I.3
Belorgey, D.4
Haq, I.5
Ordez, A.6
Kruppa, A.J.7
Duvoix, A.8
Rashid, S.T.9
Crowther, D.C.10
Marciniak, S.J.11
Lomas, D.A.12
-
234
-
-
69249104575
-
Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins
-
Kroeger H., Miranda E., MacLeod I., Pérez J., Crowther D. C., Marciniak S. J., Lomas D. A., Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins Journal of Biological Chemistry 2009 284 34 22793 22802
-
(2009)
Journal of Biological Chemistry
, vol.284
, Issue.34
, pp. 22793-22802
-
-
Kroeger, H.1
Miranda, E.2
MacLeod, I.3
Pérez, J.4
Crowther, D.C.5
Marciniak, S.J.6
Lomas, D.A.7
-
235
-
-
33645216184
-
1- antitrypsin Z are propagated in the absence of autophagic activity
-
DOI 10.1074/jbc.M509409200
-
Kamimoto T., Shoji S., Hidvegi T., Mizushima N., Umebayashi K., Perlmutter D. H., Yoshimori T., Intracellular inclusions containing mutant 1-antitrypsin Z are propagated in the absence of autophagic activity Journal of Biological Chemistry 2006 281 7 4467 4476 (Pubitemid 43847878)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.7
, pp. 4467-4476
-
-
Kamimoto, T.1
Shoji, S.2
Hidvegi, T.3
Mizushima, N.4
Umebayashi, K.5
Perlmutter, D.H.6
Yoshimori, T.7
-
236
-
-
0033671965
-
Retention of mutant 1-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response
-
Teckman J. H., Perlmutter D. H., Retention of mutant 1-antitrypsin Z in endoplasmic reticulum is associated with an autophagic response American Journal of Physiology 2000 279 5 G961 G974
-
(2000)
American Journal of Physiology
, vol.279
, Issue.5
-
-
Teckman, J.H.1
Perlmutter, D.H.2
-
237
-
-
78649300971
-
P62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both
-
Narendra D. P., Kane L. A., Hauser D. N., Fearnley I. M., Youle R. J., p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both Autophagy 2010 6 8 1090 1106
-
(2010)
Autophagy
, vol.6
, Issue.8
, pp. 1090-1106
-
-
Narendra, D.P.1
Kane, L.A.2
Hauser, D.N.3
Fearnley, I.M.4
Youle, R.J.5
-
238
-
-
77954695260
-
P62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
-
Okatsu K., Saisho K., Shimanuki M., Nakada K., Shitara H., Sou Y. S., Kimura M., Sato S., Hattori N., Komatsu M., Tanaka K., Matsuda N., P62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria Genes to Cells 2010 15 8 887 900
-
(2010)
Genes to Cells
, vol.15
, Issue.8
, pp. 887-900
-
-
Okatsu, K.1
Saisho, K.2
Shimanuki, M.3
Nakada, K.4
Shitara, H.5
Sou, Y.S.6
Kimura, M.7
Sato, S.8
Hattori, N.9
Komatsu, M.10
Tanaka, K.11
Matsuda, N.12
|