메뉴 건너뛰기




Volumn 57, Issue 2, 1999, Pages 195-206

Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease

Author keywords

Apoptosis; Heat shock protein; Mitochondrial; MPTP; Reactive oxygen species; Rotenone; Striatum; Substantia nigra

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DOPAMINERGIC NERVE CELL; MALE; MOUSE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; SUBSTANTIA NIGRA;

EID: 0033566286     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19990715)57:2<195::AID-JNR5>3.0.CO;2-P     Document Type: Article
Times cited : (417)

References (62)
  • 1
    • 0032579227 scopus 로고    scopus 로고
    • Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction
    • Aksenova MV, Aksenov MY, Carney JM, Butterfield DA, 1998. Protein oxidation and enzyme activity decline in old brown Norway rats are reduced by dietary restriction. Mech Ageing Dev 100:157-168.
    • (1998) Mech Ageing Dev , vol.100 , pp. 157-168
    • Aksenova, M.V.1    Aksenov, M.Y.2    Carney, J.M.3    Butterfield, D.A.4
  • 2
    • 0030805622 scopus 로고    scopus 로고
    • A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
    • Alam ZI, Daniel SE, Lees AJ, Marsden DC, Jenner P, Halliwell B. 1997a. A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J Neurochem 69:1326-1329.
    • (1997) J Neurochem , vol.69 , pp. 1326-1329
    • Alam, Z.I.1    Daniel, S.E.2    Lees, A.J.3    Marsden, D.C.4    Jenner, P.5    Halliwell, B.6
  • 3
    • 0030878073 scopus 로고    scopus 로고
    • Oxidative DNA damage in the parkinsonian brain: An apparent selective increase in 8-hydroxyguanine in substantia nigra
    • Alam ZI, Jenner A, Daniel SE, Lees AJ, Cairns N, Marsden CD, Jenner P, Halliwell B. 1997b. Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine in substantia nigra. J Neurochem 69:1196-1203.
    • (1997) J Neurochem , vol.69 , pp. 1196-1203
    • Alam, Z.I.1    Jenner, A.2    Daniel, S.E.3    Lees, A.J.4    Cairns, N.5    Marsden, C.D.6    Jenner, P.7    Halliwell, B.8
  • 5
    • 0028804773 scopus 로고
    • The degree of protection provided to neuronal cells by a pre-conditioning stress correlates with the amount of heat shock protein 70 it induces and not with the similarity of the subsequent stress
    • Amin V, Cumming DV, Coffin RS, Latchman DS. 1995. The degree of protection provided to neuronal cells by a pre-conditioning stress correlates with the amount of heat shock protein 70 it induces and not with the similarity of the subsequent stress. Neurosci Lett 200:85-88.
    • (1995) Neurosci Lett , vol.200 , pp. 85-88
    • Amin, V.1    Cumming, D.V.2    Coffin, R.S.3    Latchman, D.S.4
  • 6
    • 0031905933 scopus 로고    scopus 로고
    • Genetic aspects of Parkinson's disease
    • Bandmann O, Marsden CD, Wood NW. 1998. Genetic aspects of Parkinson's disease. Mov Disord 13:203-211.
    • (1998) Mov Disord , vol.13 , pp. 203-211
    • Bandmann, O.1    Marsden, C.D.2    Wood, N.W.3
  • 7
    • 0031262187 scopus 로고    scopus 로고
    • Effects of different schedules of MPTP administration on dopaminergic neurodegeneration in mice
    • Bezard E, Dovero S, Bioulac B, Gross C. 1997. Effects of different schedules of MPTP administration on dopaminergic neurodegeneration in mice. Exp Neurol 148:288-292.
    • (1997) Exp Neurol , vol.148 , pp. 288-292
    • Bezard, E.1    Dovero, S.2    Bioulac, B.3    Gross, C.4
  • 9
    • 0032925851 scopus 로고    scopus 로고
    • Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults
    • Bruce-Keller AJ, Umberger G, McFall R, Mattson MP. 1999. Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann Neurol 45:8-15.
    • (1999) Ann Neurol , vol.45 , pp. 8-15
    • Bruce-Keller, A.J.1    Umberger, G.2    McFall, R.3    Mattson, M.P.4
  • 11
    • 0027321004 scopus 로고
    • 2-deoxyglucose enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced ATP loss in the mouse brain
    • Chan P, Langston JW, Irwin I, DeLanney LE, DiMonte DA. 1993. 2-deoxyglucose enhances 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced ATP loss in the mouse brain. J Neurochem 61:610-616.
    • (1993) J Neurochem , vol.61 , pp. 610-616
    • Chan, P.1    Langston, J.W.2    Irwin, I.3    DeLanney, L.E.4    DiMonte, D.A.5
  • 12
    • 0023185105 scopus 로고
    • A dopaminergic cell line variant resistant to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Denton T, Howard BD. 1987. A dopaminergic cell line variant resistant to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. J Neurochem 49:622-630.
    • (1987) J Neurochem , vol.49 , pp. 622-630
    • Denton, T.1    Howard, B.D.2
  • 14
    • 0342275259 scopus 로고    scopus 로고
    • Caloric restriction enhances evoked DA overflow in striatum and nucleus accumbens of aged Fischer 344 rats
    • Diao LH, Bickford PC, Stevens JO, Cline EJ, Gerhardt GA. 1997. Caloric restriction enhances evoked DA overflow in striatum and nucleus accumbens of aged Fischer 344 rats. Brain Res 763:276-280.
    • (1997) Brain Res , vol.763 , pp. 276-280
    • Diao, L.H.1    Bickford, P.C.2    Stevens, J.O.3    Cline, E.J.4    Gerhardt, G.A.5
  • 15
    • 0008886654 scopus 로고    scopus 로고
    • Participation of Par-4 in degeneration of dopaminergic neurons in models of Parkinson's disease
    • in press
    • Duan W, Zhang Z, Rangnekar VM, Gash DM, Mattson MP. 1999. Participation of Par-4 in degeneration of dopaminergic neurons in models of Parkinson's disease. Ann Neurol (in press).
    • (1999) Ann Neurol
    • Duan, W.1    Zhang, Z.2    Rangnekar, V.M.3    Gash, D.M.4    Mattson, M.P.5
  • 16
    • 0030249761 scopus 로고    scopus 로고
    • Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of mouse
    • Dubey A, Forster MJ, Lal H, Sohal RS. 1996. Effect of age and caloric intake on protein oxidation in different brain regions and on behavioral functions of mouse. Arch Biochem Biophys 333:189-197.
    • (1996) Arch Biochem Biophys , vol.333 , pp. 189-197
    • Dubey, A.1    Forster, M.J.2    Lal, H.3    Sohal, R.S.4
  • 17
    • 0029872930 scopus 로고    scopus 로고
    • Caloric restriction increases the expression of heat shock protein in the gut
    • Ehrenfried JA, Evers BM, Chu KU, Townsend CM, Thompson JC. 1996. Caloric restriction increases the expression of heat shock protein in the gut. Ann Surg 223:592-597.
    • (1996) Ann Surg , vol.223 , pp. 592-597
    • Ehrenfried, J.A.1    Evers, B.M.2    Chu, K.U.3    Townsend, C.M.4    Thompson, J.C.5
  • 18
    • 77956800872 scopus 로고    scopus 로고
    • Food restriction and brain aging. The aging brain
    • Finch CE, Morgan TE. 1997. Food restriction and brain aging. The aging brain. Adv Cell Aging Gerontol 2:279-297.
    • (1997) Adv Cell Aging Gerontol , vol.2 , pp. 279-297
    • Finch, C.E.1    Morgan, T.E.2
  • 19
    • 0029845140 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease: An empirical comparison with the phenomenology of the disease in man
    • Gerlach M, Riederer P. 1996. Animal models of Parkinson's disease: an empirical comparison with the phenomenology of the disease in man. J Neural Transm 103:987-1041.
    • (1996) J Neural Transm , vol.103 , pp. 987-1041
    • Gerlach, M.1    Riederer, P.2
  • 21
    • 0031859395 scopus 로고    scopus 로고
    • Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease
    • Gu M, Cooper JM, Taanman JW, Schapira AH. 1998. Mitochondrial DNA transmission of the mitochondrial defect in Parkinson's disease. Ann Neurol 44:177-186.
    • (1998) Ann Neurol , vol.44 , pp. 177-186
    • Gu, M.1    Cooper, J.M.2    Taanman, J.W.3    Schapira, A.H.4
  • 22
    • 0033016172 scopus 로고    scopus 로고
    • Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice
    • Guo Q, Fu W, Sopher BL, Miller MW, Ware CB, Martin GM, Mattson MP. 1999. Increased vulnerability of hippocampal neurons to excitotoxic necrosis in presenilin-1 mutant knock-in mice. Nature Med 5:101-107.
    • (1999) Nature Med , vol.5 , pp. 101-107
    • Guo, Q.1    Fu, W.2    Sopher, B.L.3    Miller, M.W.4    Ware, C.B.5    Martin, G.M.6    Mattson, M.P.7
  • 23
    • 0029870841 scopus 로고    scopus 로고
    • Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1
    • Heydari AR, You S, Takahashi R, Gutsmann A, Sarge KD, Richardson A. 1996. Effect of caloric restriction on the expression of heat shock protein 70 and the activation of heat shock transcription factor 1. Dev Genet 18:114-124.
    • (1996) Dev Genet , vol.18 , pp. 114-124
    • Heydari, A.R.1    You, S.2    Takahashi, R.3    Gutsmann, A.4    Sarge, K.D.5    Richardson, A.6
  • 24
    • 0023470630 scopus 로고
    • Dietary restriction: Effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortex
    • Idrobo F, Nandy K, Mostofsky DI, Blatt L, Nandy L. 1987. Dietary restriction: effects on radial maze learning and lipofuscin pigment deposition in the hippocampus and frontal cortex. Arch Gerontol Geriatr 6:355-362.
    • (1987) Arch Gerontol Geriatr , vol.6 , pp. 355-362
    • Idrobo, F.1    Nandy, K.2    Mostofsky, D.I.3    Blatt, L.4    Nandy, L.5
  • 25
    • 0031687793 scopus 로고    scopus 로고
    • Understanding cell death in Parkinson's disease
    • Jenner P, Olanow CW. 1998. Understanding cell death in Parkinson's disease. Ann Neural 44:S72-S84.
    • (1998) Ann Neural , vol.44
    • Jenner, P.1    Olanow, C.W.2
  • 26
    • 0030986669 scopus 로고    scopus 로고
    • Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis
    • Kruman I, Bruce-Keller AJ, Bredesen DE, Waeg G, Mattson MP. 1997. Evidence that 4-hydroxynonenal mediates oxidative stress-induced neuronal apoptosis. J Neurosci 17:5089-5100.
    • (1997) J Neurosci , vol.17 , pp. 5089-5100
    • Kruman, I.1    Bruce-Keller, A.J.2    Bredesen, D.E.3    Waeg, G.4    Mattson, M.P.5
  • 28
    • 0031715849 scopus 로고    scopus 로고
    • Epidemiology versus genetics in Parkinson's disease: Progress in resolving an age-old debate
    • Langston JW. 1998. Epidemiology versus genetics in Parkinson's disease: progress in resolving an age-old debate. Ann Neurol 44:S45-S52.
    • (1998) Ann Neurol , vol.44
    • Langston, J.W.1
  • 29
    • 0033168080 scopus 로고    scopus 로고
    • 2-deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: Involvement of stress proteins
    • Lee J, Bruce-Keller AJ, Kruman I, Chan S, Mattson MP. 1999. 2-deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: involvement of stress proteins. J Neurosci Res 57:48-61.
    • (1999) J Neurosci Res , vol.57 , pp. 48-61
    • Lee, J.1    Bruce-Keller, A.J.2    Kruman, I.3    Chan, S.4    Mattson, M.P.5
  • 30
    • 0019817995 scopus 로고
    • Dietary restriction retards the age-associated loss of rat striatal dopaminergic receptors
    • Levin P, Janda JK, Joseph JA, Ingram DK, Roth GS. 1981. Dietary restriction retards the age-associated loss of rat striatal dopaminergic receptors. Science 214:561-562.
    • (1981) Science , vol.214 , pp. 561-562
    • Levin, P.1    Janda, J.K.2    Joseph, J.A.3    Ingram, D.K.4    Roth, G.S.5
  • 31
    • 0027958873 scopus 로고
    • The glucose-regulated proteins (GRP78 and GRP94): Functions, gene regulation, and applications
    • Little E, Ramakrishnan M, Roy B, Gazit G, Lee AS. 1994. The glucose-regulated proteins (GRP78 and GRP94): functions, gene regulation, and applications. Crit Rev Euk Gene Expr 4:1-18.
    • (1994) Crit Rev Euk Gene Expr , vol.4 , pp. 1-18
    • Little, E.1    Ramakrishnan, M.2    Roy, B.3    Gazit, G.4    Lee, A.S.5
  • 32
    • 0030051986 scopus 로고    scopus 로고
    • Dietary lipids and antioxidants in Parkinson's disease: A population-based, case-control study
    • Logroscino G, Marder K, Cote L, Tang MX, Shea S, Mayeux R. 1996. Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control study. Ann Neurol 39:89-94.
    • (1996) Ann Neurol , vol.39 , pp. 89-94
    • Logroscino, G.1    Marder, K.2    Cote, L.3    Tang, M.X.4    Shea, S.5    Mayeux, R.6
  • 33
    • 0026328490 scopus 로고
    • The stress protein response in cultured neurons: Characterization and evidence for a protective role in excitotoxicity
    • Lowenstein DH, Chan P, Miles M. 1991. The stress protein response in cultured neurons: characterization and evidence for a protective role in excitotoxicity. Neuron 7:1053-1060.
    • (1991) Neuron , vol.7 , pp. 1053-1060
    • Lowenstein, D.H.1    Chan, P.2    Miles, M.3
  • 35
    • 0027319561 scopus 로고
    • Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose
    • Mattson MP, Zhang Y, Bose S. 1993. Growth factors prevent mitochondrial dysfunction, loss of calcium homeostasis and cell injury, but not ATP depletion in hippocampal neurons deprived of glucose. Exp Neurol 121:1-13.
    • (1993) Exp Neurol , vol.121 , pp. 1-13
    • Mattson, M.P.1    Zhang, Y.2    Bose, S.3
  • 36
    • 0029175202 scopus 로고
    • Calcium, free radicals, and excitotoxic neuronal death in primary cell culture
    • Mattson MP, Barger SW, Begley JG, Mark RJ. 1995. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol 46:187-216.
    • (1995) Methods Cell Biol , vol.46 , pp. 187-216
    • Mattson, M.P.1    Barger, S.W.2    Begley, J.G.3    Mark, R.J.4
  • 37
    • 0030611750 scopus 로고    scopus 로고
    • Activation of NF-ΚB protects hippocampal neurons against oxidative stress-induced apoptosis: Evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration
    • Mattson MP, Goodman Y, Luo H, Fu W, Furukawa K. 1997. Activation of NF-ΚB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of Mn-SOD and suppression of peroxynitrite production and protein tyrosine nitration. J Neurosci Res 49:681-697.
    • (1997) J Neurosci Res , vol.49 , pp. 681-697
    • Mattson, M.P.1    Goodman, Y.2    Luo, H.3    Fu, W.4    Furukawa, K.5
  • 38
    • 0030990697 scopus 로고    scopus 로고
    • Reversal of parkinsonian symptoms in primates by antagonism of excitatory amino acid transmission: Potential mechanisms of action
    • Mitchell IJ, Carroll CB. 1997. Reversal of parkinsonian symptoms in primates by antagonism of excitatory amino acid transmission: potential mechanisms of action. Neurosci Biobehav Rev 21:469-475.
    • (1997) Neurosci Biobehav Rev , vol.21 , pp. 469-475
    • Mitchell, I.J.1    Carroll, C.B.2
  • 39
    • 0026587806 scopus 로고
    • Differential vulnerability of primate caudateputamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Moratalla R, Quinn B, DeLanney LE, Irwin I, Langston JW, Graybiel AM. 1992. Differential vulnerability of primate caudateputamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc Natl Acad Sci USA 89:3859-3863.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3859-3863
    • Moratalla, R.1    Quinn, B.2    DeLanney, L.E.3    Irwin, I.4    Langston, J.W.5    Graybiel, A.M.6
  • 40
    • 0030995379 scopus 로고    scopus 로고
    • Increased transcription of the astrocyte gene GFAP during middle age is attenuated by food restriction: Implications for the role of oxidative stress
    • Morgan TE, Rozovsky I, Goldsmith SK, Stone DJ, Yoshida T, Finch CE. 1997. Increased transcription of the astrocyte gene GFAP during middle age is attenuated by food restriction: implications for the role of oxidative stress. Free Rad Biol Med 23:524-528.
    • (1997) Free Rad Biol Med , vol.23 , pp. 524-528
    • Morgan, T.E.1    Rozovsky, I.2    Goldsmith, S.K.3    Stone, D.J.4    Yoshida, T.5    Finch, C.E.6
  • 43
    • 0029001576 scopus 로고
    • A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-ΚB
    • Pahl HL, Baeuerle PA. 1995. A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF-ΚB. EMBO J 14:2580-2588.
    • (1995) EMBO J , vol.14 , pp. 2580-2588
    • Pahl, H.L.1    Baeuerle, P.A.2
  • 44
    • 0025072207 scopus 로고
    • Dietary restriction slows the abnormally rapid loss of spiral ganglion neurons in C57BL/6 mice
    • Park JC, Cook KC, Verde EA. 1990. Dietary restriction slows the abnormally rapid loss of spiral ganglion neurons in C57BL/6 mice. Hear Res 48:275-279.
    • (1990) Hear Res , vol.48 , pp. 275-279
    • Park, J.C.1    Cook, K.C.2    Verde, E.A.3
  • 45
    • 0026535052 scopus 로고
    • Deterioration of spatial and nonspatial reference and working memory in aged rats: Protective effect of life-long calorie restriction
    • Pitsikas N, Algeri S. 1992. Deterioration of spatial and nonspatial reference and working memory in aged rats: protective effect of life-long calorie restriction. Neurobiol Aging 13:369-373.
    • (1992) Neurobiol Aging , vol.13 , pp. 369-373
    • Pitsikas, N.1    Algeri, S.2
  • 48
    • 0023187166 scopus 로고
    • Selective loss of subpopulations of ventral mesencephalic dopaminergic neurons in the monkey following exposure to MPTP
    • Schneider JS, Yuwiler A, Markham CH. 1987. Selective loss of subpopulations of ventral mesencephalic dopaminergic neurons in the monkey following exposure to MPTP. Brain Res 411:144-150.
    • (1987) Brain Res , vol.411 , pp. 144-150
    • Schneider, J.S.1    Yuwiler, A.2    Markham, C.H.3
  • 49
    • 0031589740 scopus 로고    scopus 로고
    • Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors
    • Seaton TA, Cooper JM, Schapira AHV. 1997. Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors. Brain Res 777:110-118.
    • (1997) Brain Res , vol.777 , pp. 110-118
    • Seaton, T.A.1    Cooper, J.M.2    Schapira, A.H.V.3
  • 50
    • 0032569676 scopus 로고    scopus 로고
    • Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins
    • Seaton TA, Cooper JM, Schapira AH. 1998. Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins. Brain Res 809:12-17.
    • (1998) Brain Res , vol.809 , pp. 12-17
    • Seaton, T.A.1    Cooper, J.M.2    Schapira, A.H.3
  • 51
    • 0029884711 scopus 로고    scopus 로고
    • Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors
    • Shimizu S, Eguchi Y, Kamiike W, Waguri S, Uchiyama Y, Matsuda H, Tsujimoto Y. 1996. Bcl-2 blocks loss of mitochondrial membrane potential while ICE inhibitors act at a different step during inhibition of death induced by respiratory chain inhibitors. Oncogene 13:21-29.
    • (1996) Oncogene , vol.13 , pp. 21-29
    • Shimizu, S.1    Eguchi, Y.2    Kamiike, W.3    Waguri, S.4    Uchiyama, Y.5    Matsuda, H.6    Tsujimoto, Y.7
  • 52
    • 0030038103 scopus 로고    scopus 로고
    • Oxidative stress, caloric restriction, and aging
    • Sohal RS, Weindruch R. 1996. Oxidative stress, caloric restriction, and aging. Science 273:59-63.
    • (1996) Science , vol.273 , pp. 59-63
    • Sohal, R.S.1    Weindruch, R.2
  • 53
    • 0028342438 scopus 로고
    • Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
    • Sohal RS, Ku HH, Agarwal S, Forster MJ, Lal H. 1994. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Aging Dev 74:121-33.
    • (1994) Mech Aging Dev , vol.74 , pp. 121-133
    • Sohal, R.S.1    Ku, H.H.2    Agarwal, S.3    Forster, M.J.4    Lal, H.5
  • 54
    • 0024829444 scopus 로고
    • The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes
    • Stewart J, Mitchell J, Kalant N. 1989. The effects of life-long food restriction on spatial memory in young and aged Fischer 344 rats measured in the eight-arm radial and the Morris water mazes. Neurobiol Aging 10:669-675.
    • (1989) Neurobiol Aging , vol.10 , pp. 669-675
    • Stewart, J.1    Mitchell, J.2    Kalant, N.3
  • 55
    • 0027504297 scopus 로고
    • Advances in our understanding of the mechanisms of the neurotoxiicty of MPTP and related compounds
    • Tipton KF, Singer TP. 1993. Advances in our understanding of the mechanisms of the neurotoxiicty of MPTP and related compounds. J Neurochem 61:1191-1206.
    • (1993) J Neurochem , vol.61 , pp. 1191-1206
    • Tipton, K.F.1    Singer, T.P.2
  • 57
    • 0030033521 scopus 로고    scopus 로고
    • The beneficial effects of dietary restriction: Reduced oxidative damage and enhanced apoptosis
    • Wachsman JT. 1996. The beneficial effects of dietary restriction: reduced oxidative damage and enhanced apoptosis. Mutat Res 350:25-34.
    • (1996) Mutat Res , vol.350 , pp. 25-34
    • Wachsman, J.T.1
  • 58
    • 0022517746 scopus 로고
    • The retardation of aging by dietary restriction: Longevity, immunity and lifetime energy intake
    • Weindruch RL, Walford S, Fligiel S, Guthrie D. 1986. The retardation of aging by dietary restriction: longevity, immunity and lifetime energy intake. J Nutr 116:641-654.
    • (1986) J Nutr , vol.116 , pp. 641-654
    • Weindruch, R.L.1    Walford, S.2    Fligiel, S.3    Guthrie, D.4
  • 61
    • 0033015485 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: Suppression of oxidative stress and stabilization of calcium homeostasis
    • Yu ZF, Luo H, Fu W, Mattson MP 1999. The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis. Exp Neurol 155:302-314.
    • (1999) Exp Neurol , vol.155 , pp. 302-314
    • Yu, Z.F.1    Luo, H.2    Fu, W.3    Mattson, M.P.4
  • 62
    • 0029555619 scopus 로고
    • Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II
    • Yun J, Tomida A, Nagata K, Tsuruo T. 1995. Glucose-regulated stresses confer resistance to VP-16 in human cancer cells through a decreased expression of DNA topoisomerase II. Oncol Res 7:583-590.
    • (1995) Oncol Res , vol.7 , pp. 583-590
    • Yun, J.1    Tomida, A.2    Nagata, K.3    Tsuruo, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.