Gene-Diet Interactions in Brain Aging and Neurodegenerative Disorders

Annals of Internal Medicine

Volumn 139, Issue 5 II, 2003, Pages 441-444

  Mattson, Mark P ^a,b  

^a NATIONAL INSTITUTE ON AGING   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; FOLIC ACID; HOMOCYSTEINE; NEUROTROPHIC FACTOR;

AGED; AGING; ALZHEIMER DISEASE; AMINO ACID BRAIN LEVEL; BRAIN FUNCTION; CALORIC INTAKE; CLINICAL TRIAL; CONFERENCE PAPER; DEGENERATIVE DISEASE; DIET; DIET SUPPLEMENTATION; DNA DAMAGE; FOLIC ACID DEFICIENCY; GENE INTERACTION; GENETIC PREDISPOSITION; HUMAN; NEUROPROTECTION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; RISK FACTOR; ANIMAL; BRAIN; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW;

AGING; ANIMALS; BRAIN; DIET; ENERGY INTAKE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; NEURODEGENERATIVE DISEASES;

EID: 0141719852     PISSN: 00034819     EISSN: None     Source Type: Journal    
DOI: 10.7326/0003-4819-139-5_part_2-200309021-00012     Document Type: Conference Paper

References (28)

1. Brody JA, Grant MD. Age-associated diseases and conditions: implications for decreasing late life morbidity. Aging (Milano). 2001;13:64-7. [PMID: 11405387]
2. Tanzi RE, Bertram L. New frontiers in Alzheimer's disease genetics. Neuron. 2001;32:181-4. [PMID: 11683989]
3. Gwinn-Hasdy K. Genetics of parkinsonism. Mov Disord. 2002;17:645-56. [PMID: 12210852]
4. Mattson MP, Pedersen WA, Duan W, Culmsee C, Camandola S. Cellular and molecular mechanisms underlying perturbed energy metabolism and neuronal degeneration in Alzheimer's and Parkinson's diseases. Ann N Y Acad Sci. 1999;893:154-75. [PMID: 10672236]
5. Beal MF. Experimental models of Parkinson's disease. Nat Rev Neurosci. 2001;2:325-34. [PMID: 11331916]
6. Logroscino G, Marder K, Cote L, Tang MX, Shea S, Mayeux R. Dietary lipids and antioxidants in Parkinson's disease: a population-based, case-control study. Ann Neurol. 1996;39:89-94. [PMID: 8572672]
7. Luchsinger JA, Tang MX, Shea S, Mayeux R. Caloric intake and the risk of Alzheimer disease. Arch Neurol. 2002;59:1258-63. [PMID: 12164721]
8. Hendrie HC, Ogunniyi A, Hall KS, Baiyewu O, Unverzagt FW, Gureje O, et al. Incidence of dementia and Alzheimer disease in 2 communities: Yoruba residing in Ibadan, Nigeria, and African Americans residing in Indianapolis, Indiana. JAMA. 2001;285:739-47. [PMID: 11176911]
9. Bruce-Keller AJ, Umberger G, McFall R, Mattson MP. Food restriction reduces brain damage and improves behavioral outcome following excitotoxic and metabolic insults. Ann Neurol. 1999;45:8-15. [PMID: 9894871]
10. Zhu H, Guo Q, Mattson MP. Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation. Brain Res. 1999;842:224-9. [PMID: 10526115]
11. Duan W, Mattson MP. Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease. J Neurosci Res. 1999;57:195-206. [PMID: 10398297]
12. Lee J, Seroogy KB, Mattson MP. Dietary restriction enhances neurotrophin expression and neurogenesis in the hippocampus of adult mice. J Neurochem. 2002;80:539-47. [PMID: 11905999]
13. Duan W, Guo Z, Mattson MP. Brain-derived neurotrophic factor mediates an excitoprotective effect of dietary restriction in mice. J Neurochem. 2001;76:619-26. [PMID: 11208925]
14. Yu ZF, Mattson MP. Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism. J Neurosci Res. 1999;57:830-9. [PMID: 10467254]
15. Refsum H, Ueland PM, Nygard O, Vollset SE. Homocysteine and cardiovascular disease. Annu Rev Med. 1998;49:31-62. [PMID: 9509248]
16. Seshadri S, Beiser A, Selhub J, Jacques PF, Rosenberg IH, D'Agostino RB, et al. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med. 2002;346:476-83. [PMID: 11844848]
17. Claske R, Smith AD, Jobst KA, Refsum H, Sutton L, Ueland PM. Folate, vitamin B12, and serum total homocysteine levels in confirmed Alzheimer disease. Arch Neurol. 1998;55:1449-55. [PMID: 9823829]
18. Kruman II, Kumaravel TS, Lohani A, Pedersen WA, Cutler RG, Kruman Y, et al. Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer's disease. J Neurosci. 2002;22:1752-62. [PMID: 11880504]
19. Duan W, Ladenheim B, Cutler RG, Kruman II, Cadet JL, Mattson MP. Dietary folate deficiency and elevated homocysteine levels endanger dopamineirgic neurons in models of Parkinson's disease. J Neurochem. 2002;80:101-10. [PMID: 11796748]
20. Kruman II, Culmsee C, Chan SL, Kruman Y, Guo Z, Penix L, et al. Homocysteine elicits a DNA damage response in neurons that promotes apoptosis and hypersensitivity to excitotoxicity. J Neurosci. 2000;20:6920-6. [PMID: 10995836]
21. Pedersen WA, Mattson MP. No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/Zn-superoxide dismutase mutant mice. Brain Res. 1999;833:117-20. [PMID: 10375685]
22. Ueland PM, Hustad S, Schneede J, Refsum H, Vollset SE. Biological and clinical implications of the MTHFR C677T polymorphism. Trends Pharmacol Sci. 2001;22:195-201. [PMID: 11282420]
23. Cutler RG, Pedersen WA, Camandola S, Rothstein JD, Mattson MP. Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis. Ann Neurol. 2002;52:448-57. [PMID: 12325074]
24. Mattson MP, ed. Diet-Brain Connections: Impact on Memory, Mood, Aging and Disease. Boston: Kluwer; 2002.
25. Ingram DK, Weindruch R, Spangler EL, Freeman JR, Walford RL. Dietary restriction benefits learning and motor performance of aged mice. J Gerontol. 1987;42:78-81. [PMID: 3794202]
26. Frame LT, Hart RW, Leakey JE. Caloric restriction as a mechanism mediating resistance to environmental disease. Environ Health Perspect. 1998;106 Suppl 1:313-24. [PMID: 9539025]
27. McCaddon A, Hudson P, Davies G, Hughes A, Williams JH, WiLkinson C. Homocysteine and cognitive decline in healthy elderly. Dement Geriatr Cogn Disord. 2001;12:309-13. [PMID: 11455131]
28. Kuhn W, Roebroek R, Blom H, van Oppenraaij D, Przuntek H, Kretschmer A, et al. Elevated plasma levels of homocysteine in Parkinson's disease. Eur Neurol. 1998;40:225-7. [PMID: 9813406]