Impairment of chaperone-mediated autophagy induces dopaminergic neurodegeneration in rats

Autophagy

Volumn 12, Issue 11, 2016, Pages 2230-2247

  Xilouri, Maria ^a   Brekk, Oeystein Roed ^a,b   Polissidis, Alexia ^a   Chrysanthou Piterou, Margarita ^c   Kloukina, Ismini ^a,d   Stefanis, Leonidas ^a,e  

^a BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d Theodor Theohari Cozzika Foundation   (Greece)

^e UNIVERSITY OF ATHENS   (Greece)

Author keywords

chaperone mediated autophagy; LAMP2A; lysosomes; Parkinson disease; synuclein

Indexed keywords

ALPHA SYNUCLEIN; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2A; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; RECEPTOR; SHORT HAIRPIN RNA; UBIQUITIN; UNCLASSIFIED DRUG; VIRUS VECTOR; CHAPERONE; SEQUESTOSOME 1; SMALL INTERFERING RNA; SQSTM1 PROTEIN, RAT;

ADENOVIRIDAE; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; CELL VACUOLE; CHAPERONE-MEDIATED AUTOPHAGY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; FEMALE; GLIOSIS; LYSOSOME; MOLECULAR PATHOLOGY; NERVE DEGENERATION; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PHENOTYPE; PROTEIN DEGRADATION; PROTEIN LOCALIZATION; RAT; RECEPTOR DOWN REGULATION; RNA TRANSPORT; SUBSTANTIA NIGRA; ANIMAL; AUTOPHAGY; DEPENDOPARVOVIRUS; DOWN REGULATION; GENE SILENCING; GENE VECTOR; GENETIC TRANSDUCTION; METABOLISM; NEOSTRIATUM; PATHOLOGY; ULTRASTRUCTURE; WISTAR RAT;

ALPHA-SYNUCLEIN; ANIMALS; AUTOPHAGY; BEHAVIOR, ANIMAL; DEPENDOVIRUS; DOPAMINERGIC NEURONS; DOWN-REGULATION; FEMALE; GENE SILENCING; GENETIC VECTORS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; MOLECULAR CHAPERONES; NEOSTRIATUM; NERVE DEGENERATION; PHENOTYPE; RATS, WISTAR; RNA, SMALL INTERFERING; SEQUESTOSOME-1 PROTEIN; SUBSTANTIA NIGRA; TRANSDUCTION, GENETIC; UBIQUITIN; VACUOLES;

EID: 84990234698     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2016.1214777     Document Type: Article

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