Age-related dysfunctions of the autophagy lysosomal pathway in hippocampal pyramidal neurons under proteasome stress

Neurobiology of Aging

Volumn 36, Issue 5, 2015, Pages 1953-1963

  Gavilán, Elena ^a,b,c   Pintado, Cristina ^b,d   Gavilan, Maria P ^b,e   Daza, Paula ^b   Sánchez Aguayo, Inmaculada ^b   Castaño, Angélica ^a,b   Ruano, Diego ^a,b  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

^b UNIVERSITY OF SEVILLE   (Spain)

^c HOSPITAL DEL MAR   (Spain)

^d Facultad de Ciencias Ambientales y Bioquimica   (Spain)

^e CABIMER Andalusian Center for Molecular Biology and Regenerative Medicine CSIC University of Seville UPO   (Spain)

Author keywords

Aging; Autophagy; GSK 3 ; Hippocampus; Neurodegeneration

Indexed keywords

GLYCOGEN SYNTHASE KINASE 3BETA; PROTEASOME; SOMATOMEDIN C; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; PROTEASOME INHIBITOR; PROTEIN; UBIQUITIN;

AGED; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HIPPOCAMPUS; LYSOSOME; MALE; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PYRAMIDAL NERVE CELL; RAT; SIGNAL TRANSDUCTION; AGING; ANIMAL; DEGENERATIVE DISEASE; GENETICS; HOMEOSTASIS; METABOLISM; PHYSIOLOGY; PROTEIN DEGRADATION; WISTAR RAT;

AGING; ANIMALS; AUTOPHAGY; GLYCOGEN SYNTHASE KINASE 3; HIPPOCAMPUS; HOMEOSTASIS; INSULIN-LIKE GROWTH FACTOR I; LYSOSOMES; MALE; NEURODEGENERATIVE DISEASES; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEASOME INHIBITORS; PROTEINS; PROTEOLYSIS; PYRAMIDAL CELLS; RATS, WISTAR; SIGNAL TRANSDUCTION; UBIQUITIN;

EID: 84933179778     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.02.025     Document Type: Article

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