Age-related changes in the proteostasis network in the brain of the naked mole-rat: Implications promoting healthy longevity

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 10, 2015, Pages 2213-2224

  Triplett, Judy C ^a   Tramutola, Antonella ^b   Swomley, Aaron ^a   Kirk, Jessime ^a   Grimes, Kelly ^c   Lewis, Kaitilyn ^c,d   Orr, Miranda ^c   Rodriguez, Karl ^c   Cai, Jian ^e   Klein, Jon B ^e   Perluigi, Marzia ^b   Buffenstein, Rochelle ^c   Butterfield, D Allan ^a,f  

^a UNIVERSITY OF KENTUCKY   (United States)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^d Mays Cancer Center at UT Health San Antonio   (United States)

^e University of Louisville School of Medicine   (United States)

^f UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Aging; MTOR; Naked mole rat; Phosphoproteomics; Proteomics; Proteostasis networks

Indexed keywords

BECLIN 1; BRAIN PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 1A 1B LIGHT CHAIN 3 I; MICROTUBULE ASSOCIATED PROTEIN 1A 1B LIGHT CHAIN 3 II; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEASOME; PROTEIN KINASE B; PROTEOME; UBIQUITIN; UBIQUITIN THIOLESTERASE; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 2;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; BRAIN; CONTROLLED STUDY; FUNCTIONAL PROTEOMICS; GROUPS BY AGE; HETEROCEPHALUS; IMMUNOCHEMISTRY; IMMUNOPRECIPITATION; LIFESPAN; LIQUID CHROMATOGRAPHY; LONGEVITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN HOMEOSTASIS; PROTEIN PHOSPHORYLATION; TANDEM MASS SPECTROMETRY; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

HETEROCEPHALUS GLABER; RODENTIA;

EID: 84939431103     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2015.08.002     Document Type: Article

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