Autophagic flux control in neurodegeneration: Progress and precision targeting—Where do we stand?

Progress in Neurobiology

Volumn 153, Issue , 2017, Pages 64-85

  Lumkwana, Dumisile ^a   du Toit, Andre ^a   Kinnear, Craig ^b   Loos, Ben ^a  

^a STELLENBOSCH UNIVERSITY   (South Africa)

^b UNIVERSITY OF STELLENBOSCH   (South Africa)

Author keywords

Alzheimer's disease; Autophagic flux; Autophagic flux assessment; Autophagic flux modulation; Autophagolysosomes; Autophagosomes; Autophagy; Autophagy defects; Huntington's disease; Lysosomes; Neurodegeneration; Parkison's disease

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MOOD STABILIZER; SPERMIDINE; TREHALOSE; APOPTOSIS REGULATORY PROTEIN; NEUROPROTECTIVE AGENT;

ACETYLATION; AUTOPHAGIC FLUX; AUTOPHAGY; BRAIN REGION; HOMEOSTASIS; HUMAN; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; REVIEW; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; DEGENERATIVE DISEASE; DRUG EFFECTS; EVIDENCE BASED MEDICINE; METABOLIC FLUX ANALYSIS; METABOLISM; MOLECULARLY TARGETED THERAPY; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; TREATMENT OUTCOME;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; EVIDENCE-BASED MEDICINE; HUMANS; METABOLIC FLUX ANALYSIS; MODELS, NEUROLOGICAL; MOLECULAR TARGETED THERAPY; NEURODEGENERATIVE DISEASES; NEURONS; NEUROPROTECTIVE AGENTS; TREATMENT OUTCOME;

EID: 85017519859     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2017.03.006     Document Type: Review

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