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Volumn 299, Issue 4, 2010, Pages

Neurodegeneration in an animal model of Parkinson's disease is exacerbated by a high-fat diet

Author keywords

Diabetes; Dopamine; Insulin resistance; Striatum; Substantia nigra

Indexed keywords

GLUCOSE; INSULIN; OXIDOPAMINE; ADRENERGIC RECEPTOR BLOCKING AGENT; CHOLESTEROL; DOPAMINE; FAT INTAKE; FENTON'S REAGENT; GLUCOSE BLOOD LEVEL; HYDROGEN PEROXIDE; IRON;

EID: 77957575432     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00449.2010     Document Type: Article
Times cited : (129)

References (59)
  • 2
    • 0023130088 scopus 로고
    • Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: Implications for behavioral recovery from brain injury
    • Altar CA, Marien MR, Marshall JF. Time course of adaptations in dopamine biosynthesis, metabolism, and release following nigrostriatal lesions: implications for behavioral recovery from brain injury. J Neurochem 48: 390-399, 1987.
    • (1987) J Neurochem , vol.48 , pp. 390-399
    • Altar, C.A.1    Marien, M.R.2    Marshall, J.F.3
  • 3
    • 0027331917 scopus 로고
    • The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls
    • DOI 10.1007/BF00978370
    • Andrew R, Watson DG, Best SA, Midgley JM, Wenlong H, Petty RK. The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls. Neurochem Res 18: 1175-1177, 1993. (Pubitemid 23306353)
    • (1993) Neurochemical Research , vol.18 , Issue.11 , pp. 1175-1177
    • Andrew, R.1    Watson, D.G.2    Best, S.A.3    Midgley, J.M.4    Wenlong, H.5    Petty, R.K.H.6
  • 4
    • 34548206868 scopus 로고
    • Clinical experience with tolbutamide in Parkinson's disease
    • Barbeau A, Giguere R, Hardy J. [Clinical experience with tolbutamide in Parkinson's disease.]. Union Med Can 90: 147-151, 1961.
    • (1961) Union Med Can , vol.90 , pp. 147-151
    • Barbeau, A.1    Giguere, R.2    Hardy, J.3
  • 5
    • 0038051345 scopus 로고    scopus 로고
    • Mitochondria, oxidative damage, and inflammation in Parkinson's disease
    • Beal MF. Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Ann N Y Acad Sci 991: 120-131, 2003.
    • (2003) Ann N Y Acad Sci , vol.991 , pp. 120-131
    • Beal, M.F.1
  • 6
    • 0035449393 scopus 로고    scopus 로고
    • Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-lesioned macaque model of Parkinson's disease
    • Bezard E, Dovero S, Prunier C, Ravenscroft P, Chalon S, Guilloteau D, Crossman AR, Bioulac B, Brotchie JM, Gross CE. Relationship between the appearance of symptoms and the level of nigrostriatal degeneration in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned macaque model of Parkinson's disease. J Neurosci 21: 6853-6861, 2001.
    • (2001) J Neurosci , vol.21 , pp. 6853-6861
    • Bezard, E.1    Dovero, S.2    Prunier, C.3    Ravenscroft, P.4    Chalon, S.5    Guilloteau, D.6    Crossman, A.R.7    Bioulac, B.8    Brotchie, J.M.9    Gross, C.E.10
  • 7
    • 0034993599 scopus 로고    scopus 로고
    • Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: Contribution to the apoptotic theory in Parkinson's disease
    • Blum D, Torch S, Lambeng N, Nissou M, Benabid AL, Sadoul R, Verna JM. Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog Neurobiol 65: 135-172, 2001.
    • (2001) Prog Neurobiol , vol.65 , pp. 135-172
    • Blum, D.1    Torch, S.2    Lambeng, N.3    Nissou, M.4    Benabid, A.L.5    Sadoul, R.6    Verna, J.M.7
  • 8
    • 50449086746 scopus 로고    scopus 로고
    • Obesity and free fatty acids
    • viii-ix
    • Boden G. Obesity and free fatty acids. Endocrinol Metab Clin North America 37: 635-646, viii-ix, 2008.
    • (2008) Endocrinol Metab Clin North America , vol.37 , pp. 635-646
    • Boden, G.1
  • 9
    • 77149128050 scopus 로고    scopus 로고
    • L-DOPA-induced 6-hydroxydopamine production in the striata of rodents is sensitive to the degree of denervation
    • Borah A, Mohanakumar KP. L-DOPA-induced 6-hydroxydopamine production in the striata of rodents is sensitive to the degree of denervation. Neurochem Int 56: 357-362.
    • Neurochem Int , vol.56 , pp. 357-362
    • Borah, A.1    Mohanakumar, K.P.2
  • 10
    • 0015145828 scopus 로고
    • Endocrine function and glucose metabolism in patients with Parkinson's disease and their alternation by L-Dopa
    • Boyd AE, 3rd Lebovitz HE, Feldman JM. Endocrine function and glucose metabolism in patients with Parkinson's disease and their alternation by L-Dopa. J Clin Endocrinol Metab 33: 829-837, 1971.
    • (1971) J Clin Endocrinol Metab , vol.33 , pp. 829-837
    • Boyd III, A.E.1    Lebovitz, H.E.2    Feldman, J.M.3
  • 12
    • 57049134614 scopus 로고    scopus 로고
    • Validation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague-Dawley rats
    • Cacho J, Sevillano J, de Castro J, Herrera E, Ramos MP. Validation of simple indexes to assess insulin sensitivity during pregnancy in Wistar and Sprague-Dawley rats. Am J Physiol Endocrinol Metab 295: E1269-E1276, 2008.
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Cacho, J.1    Sevillano, J.2    De Castro, J.3    Herrera, E.4    Ramos, M.P.5
  • 14
    • 70350447430 scopus 로고    scopus 로고
    • A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload
    • Chess DJ, Khairallah RJ, O'Shea KM, Xu W, Stanley WC. A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes without affecting development of heart failure with pressure overload. Am J Physiol Heart Circ Physiol 297: H1585-H1593, 2009.
    • (2009) Am J Physiol Heart Circ Physiol , vol.297
    • Chess, D.J.1    Khairallah, R.J.2    O'Shea, K.M.3    Xu, W.4    Stanley, W.C.5
  • 15
    • 13844275515 scopus 로고    scopus 로고
    • Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity
    • Choi JY, Jang EH, Park CS, Kang JH. Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity. Free Radic Biol Med 38: 806-816, 2005.
    • (2005) Free Radic Biol Med , vol.38 , pp. 806-816
    • Choi, J.Y.1    Jang, E.H.2    Park, C.S.3    Kang, J.H.4
  • 16
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle JT, Puttfarcken P. Oxidative stress, glutamate, and neurodegenerative disorders. Science 262: 689-695, 1993.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.T.1    Puttfarcken, P.2
  • 17
    • 57049145380 scopus 로고    scopus 로고
    • Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat
    • Davis JF, Tracy AL, Schurdak JD, Tschop MH, Lipton JW, Clegg DJ, Benoit SC. Exposure to elevated levels of dietary fat attenuates psychostimulant reward and mesolimbic dopamine turnover in the rat. Behav Neurosci 122: 1257-1263, 2008.
    • (2008) Behav Neurosci , vol.122 , pp. 1257-1263
    • Davis, J.F.1    Tracy, A.L.2    Schurdak, J.D.3    Tschop, M.H.4    Lipton, J.W.5    Clegg, D.J.6    Benoit, S.C.7
  • 18
    • 0021994683 scopus 로고
    • Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus
    • DeFronzo RA, Gunnarsson R, Bjorkman O, Olsson M, Wahren J. Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulin-dependent (type II) diabetes mellitus. J Clin Invest 76: 149-155, 1985.
    • (1985) J Clin Invest , vol.76 , pp. 149-155
    • DeFronzo, R.A.1    Gunnarsson, R.2    Bjorkman, O.3    Olsson, M.4    Wahren, J.5
  • 19
    • 0033562167 scopus 로고    scopus 로고
    • Evidence for a novel set of small heat-shock proteins that associates with the mitochondria of murine PC12 cells and protects NADH:ubiquinone oxidoreductase from heat and oxidative stress
    • Downs CA, Jones LR, Heckathorn SA. Evidence for a novel set of small heat-shock proteins that associates with the mitochondria of murine PC12 cells and protects NADH:ubiquinone oxidoreductase from heat and oxidative stress. Arch Biochem Biophys 365: 344-350, 1999.
    • (1999) Arch Biochem Biophys , vol.365 , pp. 344-350
    • Downs, C.A.1    Jones, L.R.2    Heckathorn, S.A.3
  • 20
    • 5344279749 scopus 로고    scopus 로고
    • HSP25 protects skeletal muscle cells against oxidative stress
    • Escobedo J, Pucci AM, Koh TJ. HSP25 protects skeletal muscle cells against oxidative stress. Free Radic Biol Med 37: 1455-1462, 2004.
    • (2004) Free Radic Biol Med , vol.37 , pp. 1455-1462
    • Escobedo, J.1    Pucci, A.M.2    Koh, T.J.3
  • 24
    • 33750523632 scopus 로고    scopus 로고
    • NF-κB activation by reactive oxygen species: Fifteen years later
    • Gloire G, Legrand-Poels S, Piette J. NF-κB activation by reactive oxygen species: fifteen years later. Biochem Pharmacol 72: 1493-1505, 2006.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1493-1505
    • Gloire, G.1    Legrand-Poels, S.2    Piette, J.3
  • 25
    • 53049104850 scopus 로고    scopus 로고
    • Age-related differences in skeletal muscle insulin signaling: The role of stress kinases and heat shock proteins
    • Gupte AA, Bomhoff GL, Geiger PC. Age-related differences in skeletal muscle insulin signaling: the role of stress kinases and heat shock proteins. J Appl Physiol 105: 839-848, 2008.
    • (2008) J Appl Physiol , vol.105 , pp. 839-848
    • Gupte, A.A.1    Bomhoff, G.L.2    Geiger, P.C.3
  • 26
    • 66149153033 scopus 로고    scopus 로고
    • Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats
    • Gupte AA, Bomhoff GL, Morris JK, Gorres BK, Geiger PC. Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats. J Appl Physiol 106: 1425-1434, 2009.
    • (2009) J Appl Physiol , vol.106 , pp. 1425-1434
    • Gupte, A.A.1    Bomhoff, G.L.2    Morris, J.K.3    Gorres, B.K.4    Geiger, P.C.5
  • 27
    • 62749130586 scopus 로고    scopus 로고
    • Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet
    • Gupte AA, Bomhoff GL, Swerdlow RH, Geiger PC. Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet. Diabetes 58: 567-578, 2009.
    • (2009) Diabetes , vol.58 , pp. 567-578
    • Gupte, A.A.1    Bomhoff, G.L.2    Swerdlow, R.H.3    Geiger, P.C.4
  • 28
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • Hacker H, Karin M. Regulation and function of IKK and IKK-related kinases. Sci STKE 357: re13, 2006.
    • (2006) Sci STKE , vol.357
    • Hacker, H.1    Karin, M.2
  • 29
    • 77949407188 scopus 로고    scopus 로고
    • Ageing, neurodegeneration and Parkinson's disease
    • Hindle JV. Ageing, neurodegeneration and Parkinson's disease. Age Ageing 39: 156-161, 2010.
    • (2010) Age Ageing , vol.39 , pp. 156-161
    • Hindle, J.V.1
  • 32
    • 0029414750 scopus 로고
    • Chemical evidence for 6-hydroxydopamine to be an endogenous toxic factor in the pathogenesis of Parkinson's disease
    • Jellinger K, Linert L, Kienzl E, Herlinger E, Youdim MB. Chemical evidence for 6-hydroxydopamine to be an endogenous toxic factor in the pathogenesis of Parkinson's disease. J Neural Transm 46: 297-314, 1995.
    • (1995) J Neural Transm , vol.46 , pp. 297-314
    • Jellinger, K.1    Linert, L.2    Kienzl, E.3    Herlinger, E.4    Youdim, M.B.5
  • 33
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • discussion S36-S28
    • Jenner P. Oxidative stress in Parkinson's disease. Ann Neurol 53 Suppl 3: S26-S36; discussion S36-S28, 2003.
    • (2003) Ann Neurol , vol.53 , Issue.SUPPL. 3
    • Jenner, P.1
  • 35
    • 0030598917 scopus 로고    scopus 로고
    • Dopamine, 6-hydroxydopamine, iron, and dioxygen - Their mutual interactions and possible implication in the development of Parkinson's disease
    • Linert W, Herlinger E, Jameson RF, Kienzl E, Jellinger K, Youdim MB. Dopamine, 6-hydroxydopamine, iron, and dioxygen - their mutual interactions and possible implication in the development of Parkinson's disease. Biochim Biophys Acta 1316: 160-168, 1996.
    • (1996) Biochim Biophys Acta , vol.1316 , pp. 160-168
    • Linert, W.1    Herlinger, E.2    Jameson, R.F.3    Kienzl, E.4    Jellinger, K.5    Youdim, M.B.6
  • 36
  • 37
    • 70349681975 scopus 로고    scopus 로고
    • Glutathione-a review on its role and significance in Parkinson's disease
    • Martin HL, Teismann P. Glutathione-a review on its role and significance in Parkinson's disease. FASEB J 23: 3263-3272, 2009.
    • (2009) FASEB J , vol.23 , pp. 3263-3272
    • Martin, H.L.1    Teismann, P.2
  • 38
    • 52449087540 scopus 로고    scopus 로고
    • Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus
    • Moroz N, Tong M, Longato L, Xu H, de la Monte SM. Limited Alzheimer-type neurodegeneration in experimental obesity and type 2 diabetes mellitus. J Alzheimers Dis 15: 29-44, 2008.
    • (2008) J Alzheimers Dis , vol.15 , pp. 29-44
    • Moroz, N.1    Tong, M.2    Longato, L.3    Xu, H.4    De La Monte, S.M.5
  • 39
    • 54549097933 scopus 로고    scopus 로고
    • Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease
    • Morris JK, Zhang H, Gupte AA, Bomhoff GL, Stanford JA, Geiger PC. Measures of striatal insulin resistance in a 6-hydroxydopamine model of Parkinson's disease. Brain Res 1240: 185-195, 2008.
    • (2008) Brain Res , vol.1240 , pp. 185-195
    • Morris, J.K.1    Zhang, H.2    Gupte, A.A.3    Bomhoff, G.L.4    Stanford, J.A.5    Geiger, P.C.6
  • 41
    • 34447650048 scopus 로고    scopus 로고
    • Is dopamine a physiologically relevant mediator of feeding behavior?
    • Palmiter RD. Is dopamine a physiologically relevant mediator of feeding behavior? Trends Neurosci 30: 375-381, 2007.
    • (2007) Trends Neurosci , vol.30 , pp. 375-381
    • Palmiter, R.D.1
  • 42
    • 0041816199 scopus 로고    scopus 로고
    • Heat shock protein 27 association with the I κB kinase complex regulates tumor necrosis factor alpha-induced NF-κB activation
    • Park KJ, Gaynor RB, Kwak YT. Heat shock protein 27 association with the I κB kinase complex regulates tumor necrosis factor alpha-induced NF-κB activation. J Biol Chem 278: 35272-35278, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 35272-35278
    • Park, K.J.1    Gaynor, R.B.2    Kwak, Y.T.3
  • 43
    • 0030790785 scopus 로고    scopus 로고
    • Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine: A possible contributory mechanism for neuronal degeneration in Parkinson's disease
    • Pezzella A, d'Ischia M, Napolitano A, Misuraca G, Prota G. Iron-mediated generation of the neurotoxin 6-hydroxydopamine quinone by reaction of fatty acid hydroperoxides with dopamine: a possible contributory mechanism for neuronal degeneration in Parkinson's disease. J Med Chem 40: 2211-2216, 1997.
    • (1997) J Med Chem , vol.40 , pp. 2211-2216
    • Pezzella, A.1    D'Ischia, M.2    Napolitano, A.3    Misuraca, G.4    Prota, G.5
  • 46
    • 0037435524 scopus 로고    scopus 로고
    • The impact of comorbid disease and injuries on resource use and expenditures in parkinsonism
    • Pressley JC, Louis ED, Tang MX, Cote L, Cohen PD, Glied S, Mayeux R. The impact of comorbid disease and injuries on resource use and expenditures in parkinsonism. Neurology 60: 87-93, 2003.
    • (2003) Neurology , vol.60 , pp. 87-93
    • Pressley, J.C.1    Louis, E.D.2    Tang, M.X.3    Cote, L.4    Cohen, P.D.5    Glied, S.6    Mayeux, R.7
  • 47
    • 0034109077 scopus 로고    scopus 로고
    • Obesity, insulin resistance and diabetes - A worldwide epidemic
    • Seidell JC. Obesity, insulin resistance and diabetes - a worldwide epidemic. Brit J Nutr 83 Suppl 1: S5-S8, 2000.
    • (2000) Brit J Nutr , vol.83 , Issue.SUPPL. 1
    • Seidell, J.C.1
  • 48
    • 67349112729 scopus 로고    scopus 로고
    • Iron, the substantia nigra and related neurological disorders
    • Snyder AM, Connor JR. Iron, the substantia nigra and related neurological disorders. Biochim Biophys Acta 1790: 606-614, 2009.
    • (2009) Biochim Biophys Acta , vol.1790 , pp. 606-614
    • Snyder, A.M.1    Connor, J.R.2
  • 49
    • 0036361972 scopus 로고    scopus 로고
    • Acute locomotor effects of fluoxetine, sertraline, and nomifensine in young versus aged Fischer 344 rats
    • Stanford JA, Currier TD, Gerhardt GA. Acute locomotor effects of fluoxetine, sertraline, and nomifensine in young versus aged Fischer 344 rats. Pharmacol Biochem Behav 71: 325-332, 2002.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 325-332
    • Stanford, J.A.1    Currier, T.D.2    Gerhardt, G.A.3
  • 50
    • 34247631275 scopus 로고    scopus 로고
    • Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
    • Sulzer D. Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease. Trends Neurosci 30: 244-250, 2007.
    • (2007) Trends Neurosci , vol.30 , pp. 244-250
    • Sulzer, D.1
  • 51
    • 0034637267 scopus 로고    scopus 로고
    • A Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: Environmental risk factors for Parkinson's disease?
    • Thiruchelvam M, Brockel BJ, Richfield EK, Baggs RB, Cory-Slechta D. A Potentiated and preferential effects of combined paraquat and maneb on nigrostriatal dopamine systems: environmental risk factors for Parkinson's disease? Brain Res 873: 225-234, 2000.
    • (2000) Brain Res , vol.873 , pp. 225-234
    • Thiruchelvam, M.1    Brockel, B.J.2    Richfield, E.K.3    Baggs, R.B.4    Cory-Slechta, D.5
  • 54
    • 2342466734 scopus 로고    scopus 로고
    • Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030
    • Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27: 1047-1053, 2004.
    • (2004) Diabetes Care , vol.27 , pp. 1047-1053
    • Wild, S.1    Roglic, G.2    Green, A.3    Sicree, R.4    King, H.5
  • 55
    • 55649106830 scopus 로고    scopus 로고
    • Targeting reactive oxygen species, reactive nitrogen species and inflammation in MPTP neurotoxicity and Parkinson's disease
    • Yokoyama H, Kuroiwa H, Yano R, Araki T. Targeting reactive oxygen species, reactive nitrogen species and inflammation in MPTP neurotoxicity and Parkinson's disease. Neurol Sci 29: 293-301, 2008.
    • (2008) Neurol Sci , vol.29 , pp. 293-301
    • Yokoyama, H.1    Kuroiwa, H.2    Yano, R.3    Araki, T.4
  • 56
    • 0023024150 scopus 로고
    • Activation of glucose transport in muscle by prolonged exposure to insulin. Effects of glucose and insulin concentrations
    • Young DA, Uhl JJ, Cartee GD, Holloszy JO. Activation of glucose transport in muscle by prolonged exposure to insulin. Effects of glucose and insulin concentrations. J Biol Chem 261: 16049-16053, 1986.
    • (1986) J Biol Chem , vol.261 , pp. 16049-16053
    • Young, D.A.1    Uhl, J.J.2    Cartee, G.D.3    Holloszy, J.O.4
  • 57
    • 0035979775 scopus 로고    scopus 로고
    • Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IκK
    • Yuan M, Konstantopoulos N, Lee J, Hansen L, Li ZW, Karin M, Shoelson SE. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of IκK. Science 293: 1673-1677, 2001.
    • (2001) Science , vol.293 , pp. 1673-1677
    • Yuan, M.1    Konstantopoulos, N.2    Lee, J.3    Hansen, L.4    Li, Z.W.5    Karin, M.6    Shoelson, S.E.7
  • 58
    • 11844263385 scopus 로고    scopus 로고
    • High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex
    • Zhang X, Dong F, Ren J, Driscoll MJ, Culver B. High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex. Exp Neurol 191: 318-325, 2005.
    • (2005) Exp Neurol , vol.191 , pp. 318-325
    • Zhang, X.1    Dong, F.2    Ren, J.3    Driscoll, M.J.4    Culver, B.5
  • 59
    • 0025373167 scopus 로고
    • Compensations after lesions of central dopaminergic neurons: Some clinical and basic implications
    • Zigmond MJ, Abercrombie ED, Berger TW, Grace AA, Stricker EM. Compensations after lesions of central dopaminergic neurons: some clinical and basic implications. Trends Neurosci 13: 290-296, 1990.
    • (1990) Trends Neurosci , vol.13 , pp. 290-296
    • Zigmond, M.J.1    Abercrombie, E.D.2    Berger, T.W.3    Grace, A.A.4    Stricker, E.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.