Autophagy: A druggable process that is deregulated in aging and human disease

Journal of Clinical Investigation

Volumn 125, Issue 1, 2015, Pages 1-4

  Kroemer, Guido ^a,b,c,d  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c Metabolomics Platform   (France)

^d HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A; ACYLTRANSFERASE; ADENYLATE KINASE; AUTOPHAGY PROTEIN 5; AUTOPHAGY PROTEIN 7; BECLIN 1; DEUBIQUITINASE; GENE THERAPY AGENT; K RAS PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SIRTUIN 1; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG;

AGING; ALZHEIMER DISEASE; AMYOTROPHIC LATERAL SCLEROSIS; ANTIGEN PRESENTATION; AUTOPHAGY; CARDIOVASCULAR DISEASE; GENE INACTIVATION; GENE OVEREXPRESSION; GENE REPRESSION; GENE THERAPY; GENETIC DISORDER; GENETIC MANIPULATION; HAPLOINSUFFICIENCY; HUMAN; ISCHEMIC PRECONDITIONING; LOSS OF FUNCTION MUTATION; LUNG CARCINOGENESIS; MITOPHAGY; NERVE DEGENERATION; NONHUMAN; PANCREAS CANCER; PARKINSON DISEASE; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 4 CLINICAL TRIAL (TOPIC); PROTEIN SECRETION; REVIEW; TARGET CELL; TUMOR GROWTH; ANIMAL; CARDIOVASCULAR DISEASES; DRUG EFFECTS; GENETICS; NEOPLASMS; NEURODEGENERATIVE DISEASES; PATHOLOGY; URINE;

AGING; ANIMALS; AUTOPHAGY; CARDIOVASCULAR DISEASES; GENETIC THERAPY; HUMANS; NEOPLASMS; NEURODEGENERATIVE DISEASES;

EID: 84920400982     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI78652     Document Type: Review

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