Chaperone-mediated autophagy compensates for impaired macroautophagy in the cirrhotic liver to promote hepatocellular carcinoma

Oncotarget

Volumn 8, Issue 25, 2017, Pages 40019-40036

  Chava, Srinivas ^a   Lee, Christine ^a   Aydin, Yucel ^a   Chandra, Partha K ^a   Dash, Asha ^a   Chedid, Milad ^a   Thung, Swan N ^b   Moroz, Krzysztof ^a   Wu, Tong ^a   Nayak, Nabeen C ^c   Dash, Srikanta ^a  

^a TULANE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c SIR GANGA RAM HOSPITAL   (India)

Author keywords

Chaperone mediated autophagy; Endoplasmic reticulum; Hepatocellular carcinoma; Liver cirrhosis; Macroautophagy; Pathology Section

Indexed keywords

GLUCOSE REGULATED PROTEIN 78; GLYPICAN 3; HEAT SHOCK COGNATE PROTEIN 70; HYDROXYCHLOROQUINE; LAMP 2A PROTEIN; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; PROTEIN P53; SEQUESTOSOME 1; UNCLASSIFIED DRUG; CHAPERONE; GLYPICAN; GPC3 PROTEIN, HUMAN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 70; HSPA5 PROTEIN, HUMAN; LAMP2 PROTEIN, HUMAN; SQSTM1 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER GROWTH; CELL SURVIVAL; CHAPERONE-MEDIATED AUTOPHAGY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MACROAUTOPHAGY; PROTEIN EXPRESSION; AUTOPHAGY; IMMUNOHISTOCHEMISTRY; LIVER TUMOR; LYSOSOME; METABOLISM; PATHOLOGY; TUMOR CELL LINE;

AUTOPHAGY; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM CHAPERONE BIP; GLYPICANS; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER CIRRHOSIS; LIVER NEOPLASMS; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 2; LYSOSOMES; MOLECULAR CHAPERONES; SEQUESTOSOME-1 PROTEIN;

EID: 85020993985     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.16685     Document Type: Article

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