Antagonistic controls of autophagy and glycogen accumulation by snf1p, the yeast homolog of AMP-activated protein kinase, and the cyclin-dependent kinase pho85p

Molecular and Cellular Biology

Volumn 21, Issue 17, 2001, Pages 5742-5752

  Wang, Z ^a   Wilson, W A ^a   Fujino, M A ^a   Roach, P J ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOHYDRATE; CYCLIN DEPENDENT KINASE; GLUCOSE; GLUCOSIDASE; GLYCOGEN; GLYCOGEN SYNTHASE; PHOSPHORYLASE; PROTEIN KINASE;

ARTICLE; AUTOPHAGY; DEGRADATION; GENE; GLYCOGEN METABOLISM; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

CYCLIN-DEPENDENT KINASES; FUNGAL PROTEINS; GLUCAN 1,4-ALPHA-GLUCOSIDASE; GLYCOGEN; ISOENZYMES; MULTIENZYME COMPLEXES; MUTAGENESIS; PHENOTYPE; PHOSPHOPROTEINS; PHOSPHORYLASES; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 0034898851     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.21.17.5742-5752.2001     Document Type: Article

References (64)

1. The cyclin family of budding yeast: Abundant use of a good idea
2. Rck2 kinase is a substrate for the osmotic stress-activated mitogenactivated protein kinase Hog1
3. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
4. Characterization of glycogen-deficient glc mutants of Saccharomyces cerevisiae
5. Glucose repression in yeast
6. Mutants of yeast defective in sucrose utilisation
7. Requirement of the self-glucosylating initiator proteins Gg1p and Glg2p for glycogen accumulation in Saccharomyces cerevisiae
8. The dissimilation of the carbohydrate reserves of a strain of Saccharomyces cerevisiae
9. Developmental regulation of a sporulation-specific enzyme activity in Saccharomyces cerevisiae
10. Glycogenolytic enzymes in sporulating yeast
11. Studies on the mechanisms of autophagy: Formation of the autophagic vacuole
12. Studies on the mechanisms of autophagy: Maturation of the autophagic vacuole
13. Two glycogen synthase isoforms in Saccharomyces cerevisiae are coded by distinct genes that are differentially controlled
14. Purification and properties of yeast glycogen phosphorylase a and b
15. Reserve carbohydrates metabolism in the yeast Saccharomyces cerevisiae
16. GAC1 may encode a regulatory subunit for protein phosphatase type 1 in Saccharomyces cerevisiae
17. Analyses of APG13 gene involved in autophagy in yeast. Saccharomyces cerevisiae
18. Yeast carbon catabolite repression
19. Genomic expression programs in the response of yeast cells to environmental changes
20. Glycogen: A metabolic viewpoint
21. The molecular size and shape of liver glycogen
22. Radioactive method for the assay of glycogen phosphorylases
23. The AMP-activated/SNF1 protein kinase subfamily: Metabolic sensors of the eukaryotic cell?
24. Interactions between cAMP-dependent and SNF1 protein kinases in the control of glycogen accumulation in Saccharomyces cerevisiae
25. Control of yeast glycogen synthase-2 by COOH-terminal phosphorylation
26. Pho85p, a cyclin-dependent protein kinase, and the Snf1p protein kinase act antagonistically to control glycogen accumulation in Saccharomyces cerevisiae
27. Cyclin partners determine Pho85 protein kinase substrate specificity in vitro and in vivo: Control of glycogen biosynthesis by Pc18 and Pc110
28. Yeast glycogen synthetase in the glucose 6-phosphate-dependent form. II. The effect of proteolysis
29. Molecular analysis of GPH1, the gene encoding glycogen phosphorylase in Saccharomyces cerevisiae
30. Feasting, fasting and fermenting. Glucose sensing in yeast and other cells
31. Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHOS0-PHO85
32. Tor-mediated induction of autophagy via an Apg1 protein kinase complex
33. Biogenesis and function of the yeast vacuoles
34. Apg7p/Cvt2p is required for the cytoplasm-to-vacuole targeting, macroautophagy, and peroxisome degradation pathways
35. Autophagy, cytoplasm-to-vacuole targeting pathway, and pexophagy in yeast and mammalian cells
36. Vacuolar import of proteins and organelles from the cytoplasm
37. Signaling via cAMP in fungi: Interconnections with mitogen-activated protein kinase pathways
38. Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole
39. Reserve carbohydrate metabolism in Saccharomyces cerevisiae: Responses to nutrient limitation
40. Mechanism of regulation in yeast glycogen phosphorylase
41. Apg1p, a novel protein kinase required for the autophagic process in Saccharomyces cerevisiae
42. A family of cyclin-like proteins that interact with the Pho85 cyclin-dependent kinase
43. Identification and characterization of the CLK1 gene product, a novel CaM kinase-like protein kinase from the yeast Saccharomyces cerevisiae
44. Initiation of glycogen synthesis in yeast-requirement of multiple tyrosine residues for function of the selfglucosylating Glg proteins in vivo
45. Response of a yeast glycogen synthase gene to stress
46. Novel system for monitoring autophagy in the yeast Saccharomyces cerevisiae
47. A simplified procedure for a rapid and reliable assay of both glycogen and trehalose in whole yeast cells
48. Effects of various types of stress on the metabolism of reserve carbohydrates in Saccharomyces cerevisiae: Genetic evidence for a stress-induced recycling of glycogen and trehalose
49. The comparative biochemistry of glycogen and starch
50. Characterization and localization of the sporulation glucoamylase of Saccharomyces cerevisiae
51. Glucose 6-phosphate dependent and independent forms of yeast glycogen synthetase. Their properties and interconversions
52. Two forms of yeast glycogen synthetase and their role in glycogen accumulation
53. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
54. 1 phase duration, cyclin expression, and reserve carbohydrate metabolism in Saccharomyces cerevisiae
55. Autophagy in yeast demonstrated with proteinase-deficient mutants and conditions for its induction
56. Apg7p/Cvt2p: A novel protein-activating enzyme essential for autophagy
57. 14C-glucose
58. Delection of SNVF1 alleles affects the nutrient response of yeast and resembles mutations which activate the adenylate cyclase pathway
59. PHO85, negative regulator of the PHO system, is a homolog of the protein kinase gene. CDC28, of Saccharomyces cerevisiae
60. Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae
61. A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae
62. Coregulation of starch degradation and dimorphism in the yeast Saccharomyces cerevisiae
63. PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae
64. Mitochondrial respiratory mutants in yeast inhibit glycogen accumulation by blocking activation of glycogen synthase