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Volumn 49, Issue 1, 2016, Pages 5-32

Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Ew trends in the development of miRNA therapeutic strategies in oncology (Review)

Author keywords

AntagomiR; Epithelial mesenchymal transition; Metastasis; MicroRNAs; MiR124; MiRNA replacement therapy; Peptide nucleic acids

Indexed keywords

ANTAGOMIR; CETUXIMAB; CISPLATIN; MICRORNA; MICRORNA 1; MICRORNA 122; MICRORNA 124; MICRORNA 126; MICRORNA 128; MICRORNA 137; MICRORNA 148A; MICRORNA 148B; MICRORNA 149; MICRORNA 15A; MICRORNA 16; MICRORNA 181B; MICRORNA 18A; MICRORNA 204; MICRORNA 21; MICRORNA 221; MICRORNA 29B; MICRORNA 30B; MICRORNA 31; MICRORNA 33A; MICRORNA 33B; MICRORNA 34A; MICRORNA 34B; MICRORNA 9; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

EID: 84978431893     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2016.3503     Document Type: Review
Times cited : (199)

References (372)
  • 1
  • 3
    • 84865060978 scopus 로고    scopus 로고
    • MicroRNAs as newer therapeutic targets: A big hope from a tiny player
    • Ghelani HS, Rachchh MA and Gokani RH: MicroRNAs as newer therapeutic targets: A big hope from a tiny player. J Pharmacol Pharmacother 3: 217-227, 2012.
    • (2012) J Pharmacol Pharmacother , vol.3 , pp. 217-227
    • Ghelani, H.S.1    Rachchh, M.A.2    Gokani, R.H.3
  • 4
    • 77955902024 scopus 로고    scopus 로고
    • The widespread regulation of microRNA biogenesis, function and decay
    • Krol J, Loedige I and Filipowicz W: The widespread regulation of microRNA biogenesis, function and decay. Nat Rev Genet 11: 597-610, 2010.
    • (2010) Nat Rev Genet , vol.11 , pp. 597-610
    • Krol, J.1    Loedige, I.2    Filipowicz, W.3
  • 5
    • 84880921276 scopus 로고    scopus 로고
    • Adult-specific functions of animal microRNAs
    • Sun K and Lai EC: Adult-specific functions of animal microRNAs. Nat Rev Genet 14: 535-548, 2013.
    • (2013) Nat Rev Genet , vol.14 , pp. 535-548
    • Sun, K.1    Lai, E.C.2
  • 6
    • 66049133419 scopus 로고    scopus 로고
    • Mechanisms of miRNAmediated post-transcriptional regulation in animal cells
    • Chekulaeva M and Filipowicz W: Mechanisms of miRNAmediated post-transcriptional regulation in animal cells. Curr Opin Cell Biol 21: 452-460, 2009.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 452-460
    • Chekulaeva, M.1    Filipowicz, W.2
  • 7
    • 77955644289 scopus 로고    scopus 로고
    • Mammalian microRNAs predominantly act to decrease target mRNA levels
    • Guo H, Ingolia NT, Weissman JS and Bartel DP: Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 466: 835-840, 2010.
    • (2010) Nature , vol.466 , pp. 835-840
    • Guo, H.1    Ingolia, N.T.2    Weissman, J.S.3    Bartel, D.P.4
  • 8
    • 84940107800 scopus 로고    scopus 로고
    • Genetic variants in microRNA genes: Impact on microRNA expression, function, and disease
    • Cammaerts S, Strazisar M, De Rijk P and Del Favero J: Genetic variants in microRNA genes: Impact on microRNA expression, function, and disease. Front Genet 6: 186, 2015.
    • (2015) Front Genet , vol.6 , pp. 186
    • Cammaerts, S.1    Strazisar, M.2    De Rijk, P.3    Del Favero, J.4
  • 13
    • 84891818318 scopus 로고    scopus 로고
    • MiRBase: Annotating high confidence microRNAs using deep sequencing data
    • Kozomara A and Griffiths-Jones S: miRBase: Annotating high confidence microRNAs using deep sequencing data. Nucleic Acids Res 42: D68-D73, 2014.
    • (2014) Nucleic Acids Res , vol.42 , pp. D68-D73
    • Kozomara, A.1    Griffiths-Jones, S.2
  • 15
    • 84873114749 scopus 로고    scopus 로고
    • Data submission and quality in microarray-based microRNA profiling
    • Witwer KW: Data submission and quality in microarray-based microRNA profiling. Clin Chem 59: 392-400, 2013.
    • (2013) Clin Chem , vol.59 , pp. 392-400
    • Witwer, K.W.1
  • 16
    • 84874726726 scopus 로고    scopus 로고
    • MiRCancer: A microRNAcancer association database constructed by text mining on literature
    • Xie B, Ding Q, Han H and Wu D: miRCancer: A microRNAcancer association database constructed by text mining on literature. Bioinformatics 29: 638-644, 2013.
    • (2013) Bioinformatics , vol.29 , pp. 638-644
    • Xie, B.1    Ding, Q.2    Han, H.3    Wu, D.4
  • 18
    • 77951092180 scopus 로고    scopus 로고
    • Targeting of mRNAs by multiple miRNAs: The next step
    • Peter ME: Targeting of mRNAs by multiple miRNAs: The next step. Oncogene 29: 2161-2164, 2010.
    • (2010) Oncogene , vol.29 , pp. 2161-2164
    • Peter, M.E.1
  • 19
    • 84929500836 scopus 로고    scopus 로고
    • Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells
    • Bianchi N, Finotti A, Ferracin M, Lampronti I, Zuccato C, Breveglieri G, Brognara E, Fabbri E, Borgatti M, Negrini M, et al: Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells. PLoS One 10: e0121567, 2015.
    • (2015) PLoS One , vol.10 , pp. e0121567
    • Bianchi, N.1    Finotti, A.2    Ferracin, M.3    Lampronti, I.4    Zuccato, C.5    Breveglieri, G.6    Brognara, E.7    Fabbri, E.8    Borgatti, M.9    Negrini, M.10
  • 20
    • 77950797711 scopus 로고    scopus 로고
    • MicroRNAs as gatekeepers of apoptosis
    • Subramanian S and Steer CJ: MicroRNAs as gatekeepers of apoptosis. J Cell Physiol 223: 289-298, 2010.
    • (2010) J Cell Physiol , vol.223 , pp. 289-298
    • Subramanian, S.1    Steer, C.J.2
  • 21
    • 66249139268 scopus 로고    scopus 로고
    • Cell cycle regulation by MicroRNAs in embryonic stem cells
    • Wang Y and Blelloch R: Cell cycle regulation by MicroRNAs in embryonic stem cells. Cancer Res 69: 4093-4096, 2009.
    • (2009) Cancer Res , vol.69 , pp. 4093-4096
    • Wang, Y.1    Blelloch, R.2
  • 23
  • 24
    • 84901388051 scopus 로고    scopus 로고
    • Significance and therapeutic value of miRNAs in embryonal neural tumors
    • Shalaby T, Fiaschetti G, Baumgartner M and Grotzer MA: Significance and therapeutic value of miRNAs in embryonal neural tumors. Molecules 19: 5821-5862, 2014.
    • (2014) Molecules , vol.19 , pp. 5821-5862
    • Shalaby, T.1    Fiaschetti, G.2    Baumgartner, M.3    Grotzer, M.A.4
  • 29
    • 85010834629 scopus 로고    scopus 로고
    • Exosomic microRNAs in the tumor microenvironment
    • Neviani P and Fabbri M: Exosomic microRNAs in the tumor microenvironment. Front Med Lausanne 2: 47, 2015.
    • (2015) Front Med Lausanne , vol.2 , pp. 47
    • Neviani, P.1    Fabbri, M.2
  • 32
    • 84942991041 scopus 로고    scopus 로고
    • Circulating biomarkers for gliomas
    • Westphal M and Lamszus K: Circulating biomarkers for gliomas. Nat Rev Neurol 11: 556-566, 2015.
    • (2015) Nat Rev Neurol , vol.11 , pp. 556-566
    • Westphal, M.1    Lamszus, K.2
  • 33
    • 84908501476 scopus 로고    scopus 로고
    • MicroRNA-221 and microRNA-18a identification in stool as potential biomarkers for the non-invasive diagnosis of colorectal carcinoma
    • Yau TO, Wu CW, Dong Y, Tang CM, Ng SS, Chan FK, Sung JJ and Yu J: microRNA-221 and microRNA-18a identification in stool as potential biomarkers for the non-invasive diagnosis of colorectal carcinoma. Br J Cancer 111: 1765-1771, 2014.
    • (2014) Br J Cancer , vol.111 , pp. 1765-1771
    • Yau, T.O.1    Wu, C.W.2    Dong, Y.3    Tang, C.M.4    Ng, S.S.5    Chan, F.K.6    Sung, J.J.7    Yu, J.8
  • 35
    • 33644982043 scopus 로고    scopus 로고
    • MicroRNAs as therapeutic targets
    • Czech MP: MicroRNAs as therapeutic targets. N Engl J Med 354: 1194-1195, 2006.
    • (2006) N Engl J Med , vol.354 , pp. 1194-1195
    • Czech, M.P.1
  • 36
    • 67651087321 scopus 로고    scopus 로고
    • Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications
    • Brown BD and Naldini L: Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications. Nat Rev Genet 10: 578-585, 2009.
    • (2009) Nat Rev Genet , vol.10 , pp. 578-585
    • Brown, B.D.1    Naldini, L.2
  • 37
    • 77956453939 scopus 로고    scopus 로고
    • Cancer therapy via modulation of micro RNA levels: A promising future
    • Kota SK and Balasubramanian S: Cancer therapy via modulation of micro RNA levels: A promising future. Drug Discov Today 15: 733-740, 2010.
    • (2010) Drug Discov Today , vol.15 , pp. 733-740
    • Kota, S.K.1    Balasubramanian, S.2
  • 38
    • 78751660177 scopus 로고    scopus 로고
    • Pervasive roles of microRNAs in cardiovascular biology
    • Small EM and Olson EN: Pervasive roles of microRNAs in cardiovascular biology. Nature 469: 336-342, 2011.
    • (2011) Nature , vol.469 , pp. 336-342
    • Small, E.M.1    Olson, E.N.2
  • 40
    • 84921315112 scopus 로고    scopus 로고
    • MicroRNA therapies in cancer
    • Rothschild SI: microRNA therapies in cancer. Mol Cell Ther 2: 7, 2014.
    • (2014) Mol Cell Ther , vol.2 , pp. 7
    • Rothschild, S.I.1
  • 41
    • 84903717510 scopus 로고    scopus 로고
    • Development of microRNA therapeutics is coming of age
    • van Rooij E and Kauppinen S: Development of microRNA therapeutics is coming of age. EMBO Mol Med 6: 851-864, 2014.
    • (2014) EMBO Mol Med , vol.6 , pp. 851-864
    • Van Rooij, E.1    Kauppinen, S.2
  • 42
    • 84938536913 scopus 로고    scopus 로고
    • MicroRNAs in cancer: A historical perspective on the path from discovery to therapy
    • Orellana EA and Kasinski AL: MicroRNAs in cancer: A historical perspective on the path from discovery to therapy. Cancers (Basel) 7: 1388-1405, 2015.
    • (2015) Cancers (Basel) , vol.7 , pp. 1388-1405
    • Orellana, E.A.1    Kasinski, A.L.2
  • 44
    • 84944411873 scopus 로고    scopus 로고
    • MiRNA therapeutics: A new class of drugs with potential therapeutic applications in the heart
    • Bernardo BC, Ooi JY, Lin RC and McMullen JR: miRNA therapeutics: A new class of drugs with potential therapeutic applications in the heart. Future Med Chem 7: 1771-1792, 2015.
    • (2015) Future Med Chem , vol.7 , pp. 1771-1792
    • Bernardo, B.C.1    Ooi, J.Y.2    Lin, R.C.3    McMullen, J.R.4
  • 45
    • 33645135862 scopus 로고    scopus 로고
    • Anti-miRNA oligonucleotides (AMOs): Ammunition to target miRNAs implicated in human disease?
    • Weiler J, Hunziker J and Hall J: Anti-miRNA oligonucleotides (AMOs): Ammunition to target miRNAs implicated in human disease? Gene Ther 13: 496-502, 2006.
    • (2006) Gene Ther , vol.13 , pp. 496-502
    • Weiler, J.1    Hunziker, J.2    Hall, J.3
  • 46
    • 63349085394 scopus 로고    scopus 로고
    • A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference
    • Lu Y, Xiao J, Lin H, Bai Y, Luo X, Wang Z and Yang B: A single anti-microRNA antisense oligodeoxyribonucleotide (AMO) targeting multiple microRNAs offers an improved approach for microRNA interference. Nucleic Acids Res 37: e24, 2009.
    • (2009) Nucleic Acids Res , vol.37 , pp. e24
    • Lu, Y.1    Xiao, J.2    Lin, H.3    Bai, Y.4    Luo, X.5    Wang, Z.6    Yang, B.7
  • 47
    • 83255194160 scopus 로고    scopus 로고
    • Chemical modification and design of anti-miRNA oligonucleotides
    • Lennox KA and Behlke MA: Chemical modification and design of anti-miRNA oligonucleotides. Gene Ther 18: 1111-1120, 2011.
    • (2011) Gene Ther , vol.18 , pp. 1111-1120
    • Lennox, K.A.1    Behlke, M.A.2
  • 51
    • 84922325410 scopus 로고    scopus 로고
    • Targeted electro-delivery of oligonucleotides for RNA interference: SiRNA and antimiR
    • Chabot S, Teissié J and Golzio M: Targeted electro-delivery of oligonucleotides for RNA interference: siRNA and antimiR. Adv Drug Deliv Rev 81: 161-168, 2015.
    • (2015) Adv Drug Deliv Rev , vol.81 , pp. 161-168
    • Chabot, S.1    Teissié, J.2    Golzio, M.3
  • 58
    • 84937403454 scopus 로고    scopus 로고
    • Decrease in levels of the evolutionarily conserved microRNA miR124 affects oligodendrocyte numbers in Zebrafish, Danio rerio
    • Morris JK, Chomyk A, Song P, Parker N, Deckard S, Trapp BD, Pimplikar SW and Dutta R: Decrease in levels of the evolutionarily conserved microRNA miR124 affects oligodendrocyte numbers in Zebrafish, Danio rerio. Invert Neurosci 15: 4, 2015.
    • (2015) Invert Neurosci , vol.15 , pp. 4
    • Morris, J.K.1    Chomyk, A.2    Song, P.3    Parker, N.4    Deckard, S.5    Trapp, B.D.6    Pimplikar, S.W.7    Dutta, R.8
  • 61
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells
    • Ebert MS, Neilson JR and Sharp PA: MicroRNA sponges: Competitive inhibitors of small RNAs in mammalian cells. Nat Methods 4: 721-726, 2007.
    • (2007) Nat Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 62
    • 78149303249 scopus 로고    scopus 로고
    • MicroRNA sponges: Progress and possibilities
    • Ebert MS and Sharp PA: MicroRNA sponges: Progress and possibilities. RNA 16: 2043-2050, 2010.
    • (2010) RNA , vol.16 , pp. 2043-2050
    • Ebert, M.S.1    Sharp, P.A.2
  • 65
    • 84945151207 scopus 로고    scopus 로고
    • Healing of osteoporotic bone defects by baculovirus-engineered bone marrow-derived MSCs expressing MicroRNA sponges
    • Li KC, Chang YH, Yeh CL and Hu YC: Healing of osteoporotic bone defects by baculovirus-engineered bone marrow-derived MSCs expressing MicroRNA sponges. Biomaterials 74: 155-166, 2016.
    • (2016) Biomaterials , vol.74 , pp. 155-166
    • Li, K.C.1    Chang, Y.H.2    Yeh, C.L.3    Hu, Y.C.4
  • 67
    • 84922336562 scopus 로고    scopus 로고
    • Using artificial microRNA sponges to achieve microRNA loss-of-function in cancer cells
    • Tay FC, Lim JK, Zhu H, Hin LC and Wang S: Using artificial microRNA sponges to achieve microRNA loss-of-function in cancer cells. Adv Drug Deliv Rev 81: 117-127, 2015.
    • (2015) Adv Drug Deliv Rev , vol.81 , pp. 117-127
    • Tay, F.C.1    Lim, J.K.2    Zhu, H.3    Hin, L.C.4    Wang, S.5
  • 68
    • 84871292051 scopus 로고    scopus 로고
    • Synthetic miRNA-mowers targeting miR183-96-182 cluster or miR210 inhibit growth and migration and induce apoptosis in bladder cancer cells
    • Liu Y, Han Y, Zhang H, Nie L, Jiang Z, Fa P, Gui Y and Cai Z: Synthetic miRNA-mowers targeting miR183-96-182 cluster or miR210 inhibit growth and migration and induce apoptosis in bladder cancer cells. PLoS One 7: e52280, 2012.
    • (2012) PLoS One , vol.7 , pp. e52280
    • Liu, Y.1    Han, Y.2    Zhang, H.3    Nie, L.4    Jiang, Z.5    Fa, P.6    Gui, Y.7    Cai, Z.8
  • 69
    • 35348914716 scopus 로고    scopus 로고
    • Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR430
    • Choi WY, Giraldez AJ and Schier AF: Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR430. Science 318: 271-274, 2007.
    • (2007) Science , vol.318 , pp. 271-274
    • Choi, W.Y.1    Giraldez, A.J.2    Schier, A.F.3
  • 70
    • 64549109671 scopus 로고    scopus 로고
    • Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells
    • Haraguchi T, Ozaki Y and Iba H: Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells. Nucleic Acids Res 37: e43, 2009.
    • (2009) Nucleic Acids Res , vol.37 , pp. e43
    • Haraguchi, T.1    Ozaki, Y.2    Iba, H.3
  • 72
    • 84978416017 scopus 로고    scopus 로고
    • Differential masking of natural genetic variation by miR9a in Drosophila
    • Cassidy JJ, Straughan AJ and Carthew RW: Differential masking of natural genetic variation by miR9a in Drosophila. Genetics 202: 675-687, 2016.
    • (2016) Genetics , vol.202 , pp. 675-687
    • Cassidy, J.J.1    Straughan, A.J.2    Carthew, R.W.3
  • 73
    • 79952201745 scopus 로고    scopus 로고
    • The principles of MiRNA-masking antisense oligonucleotides technology
    • Wang Z: The principles of MiRNA-masking antisense oligonucleotides technology. Methods Mol Biol 676: 43-49, 2011.
    • (2011) Methods Mol Biol , vol.676 , pp. 43-49
    • Wang, Z.1
  • 74
    • 84881315200 scopus 로고    scopus 로고
    • Managing microRNAs with vector-encoded decoy-type inhibitors
    • Bak RO, Hollensen AK and Mikkelsen JG: Managing microRNAs with vector-encoded decoy-type inhibitors. Mol Ther 21: 1478-1485, 2013.
    • (2013) Mol Ther , vol.21 , pp. 1478-1485
    • Bak, R.O.1    Hollensen, A.K.2    Mikkelsen, J.G.3
  • 75
    • 84978416006 scopus 로고    scopus 로고
    • Tiny masking locked nucleic acids effectively bind to mRNA and inhibit binding of microRNAs in relation to thermodynamic stability
    • Murakami K and Miyagishi M: Tiny masking locked nucleic acids effectively bind to mRNA and inhibit binding of microRNAs in relation to thermodynamic stability. Biomed Rep 2: 509-512, 2014.
    • (2014) Biomed Rep , vol.2 , pp. 509-512
    • Murakami, K.1    Miyagishi, M.2
  • 78
    • 84891554347 scopus 로고    scopus 로고
    • MiR206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4
    • Winbanks CE, Beyer C, Hagg A, Qian H, Sepulveda PV and Gregorevic P: miR206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4. PLoS One 8: e73589, 2013.
    • (2013) PLoS One , vol.8 , pp. e73589
    • Winbanks, C.E.1    Beyer, C.2    Hagg, A.3    Qian, H.4    Sepulveda, P.V.5    Gregorevic, P.6
  • 80
    • 84869219338 scopus 로고    scopus 로고
    • MiR34-A microRNA replacement therapy is headed to the clinic
    • Bader AG: miR34-a microRNA replacement therapy is headed to the clinic. Front Genet 3: 120, 2012.
    • (2012) Front Genet , vol.3 , pp. 120
    • Bader, A.G.1
  • 81
    • 84901319289 scopus 로고    scopus 로고
    • Targeted delivery of miRNA therapeutics for cardiovascular diseases: Opportunities and challenges
    • Kwekkeboom RF, Lei Z, Doevendans PA, Musters RJ and Sluijter JP: Targeted delivery of miRNA therapeutics for cardiovascular diseases: Opportunities and challenges. Clin Sci (Lond) 127: 351-365, 2014.
    • (2014) Clin Sci (Lond) , vol.127 , pp. 351-365
    • Kwekkeboom, R.F.1    Lei, Z.2    Doevendans, P.A.3    Musters, R.J.4    Sluijter, J.P.5
  • 82
    • 0842346437 scopus 로고    scopus 로고
    • Principles of tumor suppression
    • Sherr CJ: Principles of tumor suppression. Cell 116: 235-246, 2004.
    • (2004) Cell , vol.116 , pp. 235-246
    • Sherr, C.J.1
  • 83
    • 34247565615 scopus 로고    scopus 로고
    • The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
    • Lee YS and Dutta A: The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 21: 1025-1030, 2007.
    • (2007) Genes Dev , vol.21 , pp. 1025-1030
    • Lee, Y.S.1    Dutta, A.2
  • 84
    • 33947431322 scopus 로고    scopus 로고
    • Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation
    • Mayr C, Hemann MT and Bartel DP: Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315: 1576-1579, 2007.
    • (2007) Science , vol.315 , pp. 1576-1579
    • Mayr, C.1    Hemann, M.T.2    Bartel, D.P.3
  • 87
    • 56149110341 scopus 로고    scopus 로고
    • Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma
    • Müller DW and Bosserhoff AK: Integrin beta 3 expression is regulated by let-7a miRNA in malignant melanoma. Oncogene 27: 6698-6706, 2008.
    • (2008) Oncogene , vol.27 , pp. 6698-6706
    • Müller, D.W.1    Bosserhoff, A.K.2
  • 88
    • 42049083140 scopus 로고    scopus 로고
    • Antiproliferative effects by Let-7 repression of high-mobility group A2 in uterine leiomyoma
    • Peng Y, Laser J, Shi G, Mittal K, Melamed J, Lee P and Wei JJ: Antiproliferative effects by Let-7 repression of high-mobility group A2 in uterine leiomyoma. Mol Cancer Res 6: 663-673, 2008.
    • (2008) Mol Cancer Res , vol.6 , pp. 663-673
    • Peng, Y.1    Laser, J.2    Shi, G.3    Mittal, K.4    Melamed, J.5    Lee, P.6    Wei, J.J.7
  • 89
    • 77956901498 scopus 로고    scopus 로고
    • The promise of microRNA replacement therapy
    • Bader AG, Brown D and Winkler M: The promise of microRNA replacement therapy. Cancer Res 70: 7027-7030, 2010.
    • (2010) Cancer Res , vol.70 , pp. 7027-7030
    • Bader, A.G.1    Brown, D.2    Winkler, M.3
  • 91
    • 79960963683 scopus 로고    scopus 로고
    • MicroRNA replacement therapy for miR145 and miR33a is efficacious in a model of colon carcinoma
    • Ibrahim AF, Weirauch U, Thomas M, Grünweller A, Hartmann RK and Aigner A: MicroRNA replacement therapy for miR145 and miR33a is efficacious in a model of colon carcinoma. Cancer Res 71: 5214-5224, 2011.
    • (2011) Cancer Res , vol.71 , pp. 5214-5224
    • Ibrahim, A.F.1    Weirauch, U.2    Thomas, M.3    Grünweller, A.4    Hartmann, R.K.5    Aigner, A.6
  • 93
    • 79960211493 scopus 로고    scopus 로고
    • Tumour-suppressor microRNAs let-7 and miR101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma
    • Buechner J, Tømte E, Haug BH, Henriksen JR, Løkke C, Flægstad T and Einvik C: Tumour-suppressor microRNAs let-7 and miR101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma. Br J Cancer 105: 296-303, 2011.
    • (2011) Br J Cancer , vol.105 , pp. 296-303
    • Buechner, J.1    Tømte, E.2    Haug, B.H.3    Henriksen, J.R.4    Løkke, C.5    Flægstad, T.6    Einvik, C.7
  • 98
    • 84877097246 scopus 로고    scopus 로고
    • Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: A novel therapeutic strategy in acute myeloid leukemia
    • Huang X, Schwind S, Yu B, Santhanam R, Wang H, Hoellerbauer P, Mims A, Klisovic R, Walker AR, Chan KK, et al: Targeted delivery of microRNA-29b by transferrin-conjugated anionic lipopolyplex nanoparticles: A novel therapeutic strategy in acute myeloid leukemia. Clin Cancer Res 19: 2355-2367, 2013.
    • (2013) Clin Cancer Res , vol.19 , pp. 2355-2367
    • Huang, X.1    Schwind, S.2    Yu, B.3    Santhanam, R.4    Wang, H.5    Hoellerbauer, P.6    Mims, A.7    Klisovic, R.8    Walker, A.R.9    Chan, K.K.10
  • 99
    • 84876491657 scopus 로고    scopus 로고
    • MicroRNA-302 replacement therapy sensitizes breast cancer cells to ionizing radiation
    • Liang Z, Ahn J, Guo D, Votaw JR and Shim H: MicroRNA-302 replacement therapy sensitizes breast cancer cells to ionizing radiation. Pharm Res 30: 1008-1016, 2013.
    • (2013) Pharm Res , vol.30 , pp. 1008-1016
    • Liang, Z.1    Ahn, J.2    Guo, D.3    Votaw, J.R.4    Shim, H.5
  • 100
    • 84872494254 scopus 로고    scopus 로고
    • A systematic review of microRNA in glioblastoma multiforme: Micro-modulators in the mesenchymal mode of migration and invasion
    • Møller HG, Rasmussen AP, Andersen HH, Johnsen KB, Henriksen M and Duroux M: A systematic review of microRNA in glioblastoma multiforme: Micro-modulators in the mesenchymal mode of migration and invasion. Mol Neurobiol 47: 131-144, 2013.
    • (2013) Mol Neurobiol , vol.47 , pp. 131-144
    • Møller, H.G.1    Rasmussen, A.P.2    Andersen, H.H.3    Johnsen, K.B.4    Henriksen, M.5    Duroux, M.6
  • 103
    • 84929955552 scopus 로고    scopus 로고
    • MicroRNA-181 functions as a tumor suppressor in non-small cell lung cancer (NSCLC) by targeting Bcl-2
    • Huang P, Ye B, Yang Y, Shi J and Zhao H: MicroRNA-181 functions as a tumor suppressor in non-small cell lung cancer (NSCLC) by targeting Bcl-2. Tumour Biol 36: 3381-3387, 2015.
    • (2015) Tumour Biol , vol.36 , pp. 3381-3387
    • Huang, P.1    Ye, B.2    Yang, Y.3    Shi, J.4    Zhao, H.5
  • 104
    • 84934974299 scopus 로고    scopus 로고
    • MiR181 family: Regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets
    • Su R, Lin HS, Zhang XH, Yin XL, Ning HM, Liu B, Zhai PF, Gong JN, Shen C, Song L, et al: MiR181 family: Regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets. Oncogene 34: 3226-3239, 2015.
    • (2015) Oncogene , vol.34 , pp. 3226-3239
    • Su, R.1    Lin, H.S.2    Zhang, X.H.3    Yin, X.L.4    Ning, H.M.5    Liu, B.6    Zhai, P.F.7    Gong, J.N.8    Shen, C.9    Song, L.10
  • 105
    • 84936878562 scopus 로고    scopus 로고
    • MiR204 mediates post-transcriptional down-regulation of PHOX2B gene expression in neuroblastoma cells
    • Bachetti T, Di Zanni E, Ravazzolo R and Ceccherini I: miR204 mediates post-transcriptional down-regulation of PHOX2B gene expression in neuroblastoma cells. Biochim Biophys Acta 1849: 1057-1065, 2015.
    • (2015) Biochim Biophys Acta , vol.1849 , pp. 1057-1065
    • Bachetti, T.1    Zanni E, D.I.2    Ravazzolo, R.3    Ceccherini, I.4
  • 106
    • 84934981317 scopus 로고    scopus 로고
    • MiR340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancer
    • Fernandez S, Risolino M, Mandia N, Talotta F, Soini Y, Incoronato M, Condorelli G, Banfi S and Verde P: miR340 inhibits tumor cell proliferation and induces apoptosis by targeting multiple negative regulators of p27 in non-small cell lung cancer. Oncogene 34: 3240-3250, 2015.
    • (2015) Oncogene , vol.34 , pp. 3240-3250
    • Fernandez, S.1    Risolino, M.2    Mandia, N.3    Talotta, F.4    Soini, Y.5    Incoronato, M.6    Condorelli, G.7    Banfi, S.8    Verde, P.9
  • 107
    • 84943628642 scopus 로고    scopus 로고
    • Tumor suppressor microRNA-18a regulates tumor proliferation and invasion by targeting TBPL1 in colorectal cancer cells
    • Liu G, Liu Y, Yang Z, Wang J, Li D and Zhang X: Tumor suppressor microRNA-18a regulates tumor proliferation and invasion by targeting TBPL1 in colorectal cancer cells. Mol Med Rep 12: 7643-7648, 2015.
    • (2015) Mol Med Rep , vol.12 , pp. 7643-7648
    • Liu, G.1    Liu, Y.2    Yang, Z.3    Wang, J.4    Li, D.5    Zhang, X.6
  • 108
    • 84938651885 scopus 로고    scopus 로고
    • MicroRNA-320a acts as a tumor suppressor by targeting BCR/ABL oncogene in chronic myeloid leukemia
    • Xishan Z, Ziying L, Jing D and Gang L: MicroRNA-320a acts as a tumor suppressor by targeting BCR/ABL oncogene in chronic myeloid leukemia. Sci Rep 5: 12460, 2015.
    • (2015) Sci Rep , vol.5 , pp. 12460
    • Xishan, Z.1    Ziying, L.2    Jing, D.3    Gang, L.4
  • 109
    • 84930521497 scopus 로고    scopus 로고
    • MicroRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest
    • Zhao Z, Ma X, Sung D, Li M, Kosti A, Lin G, Chen Y, Pertsemlidis A, Hsiao TH and Du L: microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest. RNA Biol 12: 538-554, 2015.
    • (2015) RNA Biol , vol.12 , pp. 538-554
    • Zhao, Z.1    Ma, X.2    Sung, D.3    Li, M.4    Kosti, A.5    Lin, G.6    Chen, Y.7    Pertsemlidis, A.8    Hsiao, T.H.9    Du, L.10
  • 111
    • 84923084512 scopus 로고    scopus 로고
    • The molecular mechanisms and therapeutic potential of microRNA-7 in cancer
    • Gu DN, Huang Q and Tian L: The molecular mechanisms and therapeutic potential of microRNA-7 in cancer. Expert Opin Ther Targets 19: 415-426, 2015.
    • (2015) Expert Opin Ther Targets , vol.19 , pp. 415-426
    • Gu, D.N.1    Huang, Q.2    Tian, L.3
  • 112
    • 84860011976 scopus 로고    scopus 로고
    • MicroRNA1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers
    • Nohata N, Hanazawa T, Enokida H and Seki N: microRNA1/133a and microRNA-206/133b clusters: Dysregulation and functional roles in human cancers. Oncotarget 3: 9-21, 2012.
    • (2012) Oncotarget , vol.3 , pp. 9-21
    • Nohata, N.1    Hanazawa, T.2    Enokida, H.3    Seki, N.4
  • 114
    • 84942873245 scopus 로고    scopus 로고
    • EGF receptor pomotes prostate cancer bone metastasis by downregulating miR1 and activating TWIST1
    • Chang YS, Chen WY, Yin JJ, Sheppard-Tillman H, Huang J and Liu YN: EGF receptor pomotes prostate cancer bone metastasis by downregulating miR1 and activating TWIST1. Cancer Res 75: 3077-3086, 2015.
    • (2015) Cancer Res , vol.75 , pp. 3077-3086
    • Chang, Y.S.1    Chen, W.Y.2    Yin, J.J.3    Sheppard-Tillman, H.4    Huang, J.5    Liu, Y.N.6
  • 115
    • 84907895333 scopus 로고    scopus 로고
    • MiR7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 and reverses the EMT of breast cancer stem cells by downregulating the STAT3 pathway
    • Zhang H, Cai K, Wang J, Wang X, Cheng K, Shi F, Jiang L, Zhang Y and Dou J: MiR7, inhibited indirectly by lincRNA HOTAIR, directly inhibits SETDB1 and reverses the EMT of breast cancer stem cells by downregulating the STAT3 pathway. Stem Cells 32: 2858-2868, 2014a.
    • (2014) Stem Cells , vol.32 , pp. 2858-2868
    • Zhang, H.1    Cai, K.2    Wang, J.3    Wang, X.4    Cheng, K.5    Shi, F.6    Jiang, L.7    Zhang, Y.8    Dou, J.9
  • 117
    • 84901245983 scopus 로고    scopus 로고
    • MicroRNA-7 inhibits tumor metastasis and reverses epithelial-mesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancer
    • Zhou X, Hu Y, Dai L, Wang Y, Zhou J, Wang W, Di W and Qiu L: MicroRNA-7 inhibits tumor metastasis and reverses epithelial-mesenchymal transition through AKT/ERK1/2 inactivation by targeting EGFR in epithelial ovarian cancer. PLoS One 9: e96718, 2014.
    • (2014) PLoS One , vol.9 , pp. e96718
    • Zhou, X.1    Hu, Y.2    Dai, L.3    Wang, Y.4    Zhou, J.5    Wang, W.6    Di, W.7    Qiu, L.8
  • 122
    • 84873107500 scopus 로고    scopus 로고
    • MicroRNA-9 suppresses the proliferation, invasion and metastasis of gastric cancer cells through targeting cyclin D1 and Ets1
    • Zheng L, Qi T, Yang D, Qi M, Li D, Xiang X, Huang K and Tong Q: microRNA-9 suppresses the proliferation, invasion and metastasis of gastric cancer cells through targeting cyclin D1 and Ets1. PLoS One 8: e55719, 2013.
    • (2013) PLoS One , vol.8 , pp. e55719
    • Zheng, L.1    Qi, T.2    Yang, D.3    Qi, M.4    Li, D.5    Xiang, X.6    Huang, K.7    Tong, Q.8
  • 123
    • 74249084440 scopus 로고    scopus 로고
    • MiR15a and miR16-1 in cancer: Discovery, function and future perspectives
    • Aqeilan RI, Calin GA and Croce CM: miR15a and miR16-1 in cancer: Discovery, function and future perspectives. Cell Death Differ 17: 215-220, 2010.
    • (2010) Cell Death Differ , vol.17 , pp. 215-220
    • Aqeilan, R.I.1    Calin, G.A.2    Croce, C.M.3
  • 127
  • 128
    • 84964059110 scopus 로고    scopus 로고
    • Up-regulation of microRNA-16 in glioblastoma inhibits the function of endothelial cells and tumor angiogenesis by targeting Bmi-1
    • Chen F, Chen L, He H, Huang W, Zhang R, Li P, et al: Up-regulation of microRNA-16 in glioblastoma inhibits the function of endothelial cells and tumor angiogenesis by targeting Bmi-1. Anticancer Agents Med Chem, 2015.
    • (2015) Anticancer Agents Med Chem
    • Chen, F.1    Chen, L.2    He, H.3    Huang, W.4    Zhang, R.5    Li, P.6
  • 129
    • 84911445892 scopus 로고    scopus 로고
    • MiR18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells
    • Humphreys KJ, McKinnon RA and Michael MZ: miR18a inhibits CDC42 and plays a tumour suppressor role in colorectal cancer cells. PLoS One 9: e112288, 2014.
    • (2014) PLoS One , vol.9 , pp. e112288
    • Humphreys, K.J.1    McKinnon, R.A.2    Michael, M.Z.3
  • 134
    • 67650588646 scopus 로고    scopus 로고
    • MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
    • Garzon R, Liu S, Fabbri M, Liu Z, Heaphy CE, Callegari E, Schwind S, Pang J, Yu J, Muthusamy N, et al: MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood 113: 6411-6418, 2009b.
    • (2009) Blood , vol.113 , pp. 6411-6418
    • Garzon, R.1    Liu, S.2    Fabbri, M.3    Liu, Z.4    Heaphy, C.E.5    Callegari, E.6    Schwind, S.7    Pang, J.8    Yu, J.9    Muthusamy, N.10
  • 135
    • 69249143283 scopus 로고    scopus 로고
    • MiR29 suppression of osteonectin in osteoblasts: Regulation during differentiation and by canonical Wnt signaling
    • Kapinas K, Kessler CB and Delany AM: miR29 suppression of osteonectin in osteoblasts: Regulation during differentiation and by canonical Wnt signaling. J Cell Biochem 108: 216-224, 2009.
    • (2009) J Cell Biochem , vol.108 , pp. 216-224
    • Kapinas, K.1    Kessler, C.B.2    Delany, A.M.3
  • 136
    • 34548687035 scopus 로고    scopus 로고
    • MiR29 regulates Mcl-1 protein expression and apoptosis
    • Mott JL, Kobayashi S, Bronk SF and Gores GJ: miR29 regulates Mcl-1 protein expression and apoptosis. Oncogene 26: 6133-6140, 2007.
    • (2007) Oncogene , vol.26 , pp. 6133-6140
    • Mott, J.L.1    Kobayashi, S.2    Bronk, S.F.3    Gores, G.J.4
  • 138
    • 77950602604 scopus 로고    scopus 로고
    • Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
    • Xiong Y, Fang JH, Yun JP, Yang J, Zhang Y, Jia WH and Zhuang SM: Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma. Hepatology 51: 836-845, 2010.
    • (2010) Hepatology , vol.51 , pp. 836-845
    • Xiong, Y.1    Fang, J.H.2    Yun, J.P.3    Yang, J.4    Zhang, Y.5    Jia, W.H.6    Zhuang, S.M.7
  • 142
    • 84908322095 scopus 로고    scopus 로고
    • Overexpression of microRNA-30b improves adenovirus-mediated p53 cancer gene therapy for laryngeal carcinoma
    • Li L and Wang B: Overexpression of microRNA-30b improves adenovirus-mediated p53 cancer gene therapy for laryngeal carcinoma. Int J Mol Sci 15: 19729-19740, 2014.
    • (2014) Int J Mol Sci , vol.15 , pp. 19729-19740
    • Li, L.1    Wang, B.2
  • 145
    • 79953129211 scopus 로고    scopus 로고
    • WAVE3, an actin remodeling protein, is regulated by the metastasis suppressor microRNA, miR31, during the invasion-metastasis cascade
    • Sossey-Alaoui K, Downs-Kelly E, Das M, Izem L, Tubbs R and Plow EF: WAVE3, an actin remodeling protein, is regulated by the metastasis suppressor microRNA, miR31, during the invasion-metastasis cascade. Int J Cancer 129: 1331-1343, 2011.
    • (2011) Int J Cancer , vol.129 , pp. 1331-1343
    • Sossey-Alaoui, K.1    Downs-Kelly, E.2    Das, M.3    Izem, L.4    Tubbs, R.5    Plow, E.F.6
  • 147
    • 84919932286 scopus 로고    scopus 로고
    • MicroRNA-33b suppresses migration and invasion by targeting c-Myc in osteosarcoma cells
    • Xu N, Li Z, Yu Z, Yan F, Liu Y, Lu X and Yang W: MicroRNA-33b suppresses migration and invasion by targeting c-Myc in osteosarcoma cells. PLoS One 9: e115300, 2014.
    • (2014) PLoS One , vol.9 , pp. e115300
    • Xu, N.1    Li, Z.2    Yu, Z.3    Yan, F.4    Liu, Y.5    Lu, X.6    Yang, W.7
  • 151
  • 152
    • 85009823449 scopus 로고    scopus 로고
    • MicroRNA-34a as a therapeutic agent against human cancer
    • Saito Y, Nakaoka T and Saito H: microRNA-34a as a therapeutic agent against human cancer. J Clin Med 4: 1951-1959, 2015.
    • (2015) J Clin Med , vol.4 , pp. 1951-1959
    • Saito, Y.1    Nakaoka, T.2    Saito, H.3
  • 156
    • 84883742665 scopus 로고    scopus 로고
    • MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1
    • Yang S, Li Y, Gao J, Zhang T, Li S, Luo A, Chen H, Ding F, Wang X and Liu Z: MicroRNA-34 suppresses breast cancer invasion and metastasis by directly targeting Fra-1. Oncogene 32: 4294-4303, 2013.
    • (2013) Oncogene , vol.32 , pp. 4294-4303
    • Yang, S.1    Li, Y.2    Gao, J.3    Zhang, T.4    Li, S.5    Luo, A.6    Chen, H.7    Ding, F.8    Wang, X.9    Liu, Z.10
  • 157
    • 84866018690 scopus 로고    scopus 로고
    • TGF-miR34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma
    • Yang P, Li QJ, Feng Y, Zhang Y, Markowitz GJ, Ning S, Deng Y, Zhao J, Jiang S, Yuan Y, et al: TGF-miR34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma. Cancer Cell 22: 291-303, 2012.
    • (2012) Cancer Cell , vol.22 , pp. 291-303
    • Yang, P.1    Li, Q.J.2    Feng, Y.3    Zhang, Y.4    Markowitz, G.J.5    Ning, S.6    Deng, Y.7    Zhao, J.8    Jiang, S.9    Yuan, Y.10
  • 160
    • 84873654466 scopus 로고    scopus 로고
    • MicroRNA-34b functions as a tumor suppressor and acts as a nodal point in the feedback loop with Met
    • Wang LG, Ni Y, Su BH, Mu XR, Shen HC and Du JJ: MicroRNA-34b functions as a tumor suppressor and acts as a nodal point in the feedback loop with Met. Int J Oncol 42: 957-962, 2013.
    • (2013) Int J Oncol , vol.42 , pp. 957-962
    • Wang, L.G.1    Ni, Y.2    Su, B.H.3    Mu, X.R.4    Shen, H.C.5    Du, J.J.6
  • 161
    • 84929957629 scopus 로고    scopus 로고
    • Functional analysis of miR34c as a putative tumor suppressor in high-grade serous ovarian cancer
    • Yu Z, Kim J, He L, Creighton CJ, Gunaratne PH, Hawkins SM and Matzuk MM: Functional analysis of miR34c as a putative tumor suppressor in high-grade serous ovarian cancer. Biol Reprod 91: 113, 2014.
    • (2014) Biol Reprod , vol.91 , pp. 113
    • Yu, Z.1    Kim, J.2    He, L.3    Creighton, C.J.4    Gunaratne, P.H.5    Hawkins, S.M.6    Matzuk, M.M.7
  • 162
    • 85006201214 scopus 로고    scopus 로고
    • MicroRNA-101-3p suppresses cell proliferation, invasion and enhances chemotherapeutic sensitivity in salivary gland adenoid cystic carcinoma by targeting Pim-1
    • Liu XY, Liu ZJ, He H, Zhang C and Wang YL: MicroRNA-101-3p suppresses cell proliferation, invasion and enhances chemotherapeutic sensitivity in salivary gland adenoid cystic carcinoma by targeting Pim-1. Am J Cancer Res 5: 3015-3029, 2015.
    • (2015) Am J Cancer Res , vol.5 , pp. 3015-3029
    • Liu, X.Y.1    Liu, Z.J.2    He, H.3    Zhang, C.4    Wang, Y.L.5
  • 165
    • 80855143652 scopus 로고    scopus 로고
    • Silencing of miR124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR
    • Huang TC, Chang HY, Chen CY, Wu PY, Lee H, Liao YF, Hsu WM, Huang HC and Juan HF: Silencing of miR124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR. FEBS Lett 585: 3582-3586, 2011.
    • (2011) FEBS Lett , vol.585 , pp. 3582-3586
    • Huang, T.C.1    Chang, H.Y.2    Chen, C.Y.3    Wu, P.Y.4    Lee, H.5    Liao, Y.F.6    Hsu, W.M.7    Huang, H.C.8    Juan, H.F.9
  • 167
    • 84855191863 scopus 로고    scopus 로고
    • The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2
    • Zheng F, Liao YJ, Cai MY, Liu YH, Liu TH, Chen SP, Bian XW, Guan XY, Lin MC, Zeng YX, et al: The putative tumour suppressor microRNA-124 modulates hepatocellular carcinoma cell aggressiveness by repressing ROCK2 and EZH2. Gut 61: 278-289, 2012.
    • (2012) Gut , vol.61 , pp. 278-289
    • Zheng, F.1    Liao, Y.J.2    Cai, M.Y.3    Liu, Y.H.4    Liu, T.H.5    Chen, S.P.6    Bian, X.W.7    Guan, X.Y.8    Lin, M.C.9    Zeng, Y.X.10
  • 168
    • 84954568459 scopus 로고    scopus 로고
    • MiR124 exerts tumor suppressive functions on the cell proliferation, motility and angiogenesis of bladder cancer by fine-tuning UHRF1
    • Wang X, Wu Q, Xu B, Wang P, Fan W, Cai Y, Gu X and Meng F: miR124 exerts tumor suppressive functions on the cell proliferation, motility and angiogenesis of bladder cancer by fine-tuning UHRF1. FEBS J 282: 4376-4388, 2015.
    • (2015) FEBS J , vol.282 , pp. 4376-4388
    • Wang, X.1    Wu, Q.2    Xu, B.3    Wang, P.4    Fan, W.5    Cai, Y.6    Gu, X.7    Meng, F.8
  • 169
    • 84939188065 scopus 로고    scopus 로고
    • MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling
    • Zhang C, Hu Y, Wan J and He H: MicroRNA-124 suppresses the migration and invasion of osteosarcoma cells via targeting ROR2-mediated non-canonical Wnt signaling. Oncol Rep 34: 2195-2201, 2015.
    • (2015) Oncol Rep , vol.34 , pp. 2195-2201
    • Zhang, C.1    Hu, Y.2    Wan, J.3    He, H.4
  • 170
    • 84928406631 scopus 로고    scopus 로고
    • NF-B-mediated miR124 suppresses metastasis of non-small-cell lung cancer by targeting MYO10
    • Sun Y, Ai X, Shen S and Lu S: NF-B-mediated miR124 suppresses metastasis of non-small-cell lung cancer by targeting MYO10. Oncotarget 6: 8244-8254, 2015a.
    • (2015) Oncotarget , vol.6 , pp. 8244-8254
    • Sun, Y.1    Ai, X.2    Shen, S.3    Lu, S.4
  • 171
    • 84929603704 scopus 로고    scopus 로고
    • An updated role of microRNA-124 in central nervous system disorders: A review
    • Sun Y, Luo ZM, Guo XM, Su DF and Liu X: An updated role of microRNA-124 in central nervous system disorders: A review. Front Cell Neurosci 9: 193, 2015b.
    • (2015) Front Cell Neurosci , vol.9 , pp. 193
    • Sun, Y.1    Luo, Z.M.2    Guo, X.M.3    Su, D.F.4    Liu, X.5
  • 173
    • 84928150229 scopus 로고    scopus 로고
    • Down-regulation of microRNA-124 is correlated with tumor metastasis and poor prognosis in patients with lung cancer
    • Zhang Y, Li H, Han J and Zhang Y: Down-regulation of microRNA-124 is correlated with tumor metastasis and poor prognosis in patients with lung cancer. Int J Clin Exp Pathol 8: 1967-1972, 2015.
    • (2015) Int J Clin Exp Pathol , vol.8 , pp. 1967-1972
    • Zhang, Y.1    Li, H.2    Han, J.3    Zhang, Y.4
  • 174
    • 70350728790 scopus 로고    scopus 로고
    • The epidermal growth factor receptor responsive miR125a represses mesenchymal morphology in ovarian cancer cells
    • Cowden Dahl KD, Dahl R, Kruichak JN, Hudson LG: The epidermal growth factor receptor responsive miR125a represses mesenchymal morphology in ovarian cancer cells. Neoplasia 11: 1208-1215, 2009.
    • (2009) Neoplasia , vol.11 , pp. 1208-1215
    • Cowden Dahl, K.D.1    Dahl, R.2    Kruichak, J.N.3    Hudson, L.G.4
  • 175
    • 84944463522 scopus 로고    scopus 로고
    • MiR125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3
    • Fan Z, Cui H, Xu X, Lin Z, Zhang X, Kang L, Han B, Meng J, Yan Z, Yan X, et al: MiR125a suppresses tumor growth, invasion and metastasis in cervical cancer by targeting STAT3. Oncotarget 6: 25266-25280, 2015.
    • (2015) Oncotarget , vol.6 , pp. 25266-25280
    • Fan, Z.1    Cui, H.2    Xu, X.3    Lin, Z.4    Zhang, X.5    Kang, L.6    Han, B.7    Meng, J.8    Yan, Z.9    Yan, X.10
  • 176
    • 73949116135 scopus 로고    scopus 로고
    • MiR126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7
    • Sun Y, Bai Y, Zhang F, Wang Y, Guo Y and Guo L: miR126 inhibits non-small cell lung cancer cells proliferation by targeting EGFL7. Biochem Biophys Res Commun 391: 1483-1489, 2010.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1483-1489
    • Sun, Y.1    Bai, Y.2    Zhang, F.3    Wang, Y.4    Guo, Y.5    Guo, L.6
  • 177
    • 84941985345 scopus 로고    scopus 로고
    • MiR126-3p inhibits thyroid cancer cell growth and metastasis, and is associated with aggressive thyroid cancer
    • Xiong Y, Kotian S, Zeiger MA, Zhang L and Kebebew E: miR126-3p inhibits thyroid cancer cell growth and metastasis, and is associated with aggressive thyroid cancer. PLoS One 10: e0130496, 2015.
    • (2015) PLoS One , vol.10 , pp. e0130496
    • Xiong, Y.1    Kotian, S.2    Zeiger, M.A.3    Zhang, L.4    Kebebew, E.5
  • 178
    • 84938632069 scopus 로고    scopus 로고
    • MiR126 regulated breast cancer cell invasion by targeting ADAM9
    • Wang CZ, Yuan P and Li Y: MiR126 regulated breast cancer cell invasion by targeting ADAM9. Int J Clin Exp Pathol 8: 6547-6553, 2015.
    • (2015) Int J Clin Exp Pathol , vol.8 , pp. 6547-6553
    • Wang, C.Z.1    Yuan, P.2    Li, Y.3
  • 179
    • 84939143586 scopus 로고    scopus 로고
    • MiR126 inhibits papillary thyroid carcinoma growth by targeting LRP6
    • Wen Q, Zhao J, Bai L, Wang T, Zhang H and Ma Q: miR126 inhibits papillary thyroid carcinoma growth by targeting LRP6. Oncol Rep 34: 2202-2210, 2015.
    • (2015) Oncol Rep , vol.34 , pp. 2202-2210
    • Wen, Q.1    Zhao, J.2    Bai, L.3    Wang, T.4    Zhang, H.5    Ma, Q.6
  • 180
    • 84925283601 scopus 로고    scopus 로고
    • MiR126 inhibits cell growth, invasion, and migration of osteosarcoma cells by downregulating ADAM-9
    • Jiang L, He A, Zhang Q and Tao C: miR126 inhibits cell growth, invasion, and migration of osteosarcoma cells by downregulating ADAM-9. Tumour Biol 35: 12645-12654, 2014.
    • (2014) Tumour Biol , vol.35 , pp. 12645-12654
    • Jiang, L.1    He, A.2    Zhang, Q.3    Tao, C.4
  • 181
    • 84908067975 scopus 로고    scopus 로고
    • MiR126-3p suppresses tumor metastasis and angiogenesis of hepatocellular carcinoma by targeting LRP6 and PIK3R2
    • Du C, Lv Z, Cao L, Ding C, Gyabaah OA, Xie H, Zhou L, Wu J and Zheng S: MiR126-3p suppresses tumor metastasis and angiogenesis of hepatocellular carcinoma by targeting LRP6 and PIK3R2. J Transl Med 12: 259, 2014.
    • (2014) J Transl Med , vol.12 , pp. 259
    • Du, C.1    Lv, Z.2    Cao, L.3    Ding, C.4    Gyabaah, O.A.5    Xie, H.6    Zhou, L.7    Wu, J.8    Zheng, S.9
  • 182
    • 84882686726 scopus 로고    scopus 로고
    • Epigenetic silencing of miR126 contributes to tumor invasion and angiogenesis in colorectal cancer
    • Zhang Y, Wang X, Xu B, Wang B, Wang Z, Liang Y, Zhou J, Hu J and Jiang B: Epigenetic silencing of miR126 contributes to tumor invasion and angiogenesis in colorectal cancer. Oncol Rep 30: 1976-1984, 2013.
    • (2013) Oncol Rep , vol.30 , pp. 1976-1984
    • Zhang, Y.1    Wang, X.2    Xu, B.3    Wang, B.4    Wang, Z.5    Liang, Y.6    Zhou, J.7    Hu, J.8    Jiang, B.9
  • 183
    • 84855813448 scopus 로고    scopus 로고
    • A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells
    • Png KJ, Halberg N, Yoshida M and Tavazoie SF: A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells. Nature 481: 190-194, 2011.
    • (2011) Nature , vol.481 , pp. 190-194
    • Png, K.J.1    Halberg, N.2    Yoshida, M.3    Tavazoie, S.F.4
  • 187
    • 84928905894 scopus 로고    scopus 로고
    • MiR128-3p suppresses hepatocellular carcinoma proliferation by regulating PIK3R1 and is correlated with the prognosis of HCC patients
    • Huang CY, Huang XP, Zhu JY, Chen ZG, Li XJ, Zhang XH, Huang S, He JB, Lian F, Zhao YN, et al: miR128-3p suppresses hepatocellular carcinoma proliferation by regulating PIK3R1 and is correlated with the prognosis of HCC patients. Oncol Rep 33: 2889-2898, 2015.
    • (2015) Oncol Rep , vol.33 , pp. 2889-2898
    • Huang, C.Y.1    Huang, X.P.2    Zhu, J.Y.3    Chen, Z.G.4    Li, X.J.5    Zhang, X.H.6    Huang, S.7    He, J.B.8    Lian, F.9    Zhao, Y.N.10
  • 190
    • 84874115537 scopus 로고    scopus 로고
    • MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2
    • Liang L, Li X, Zhang X, Lv Z, He G, Zhao W, Ren X, Li Y, Bian X, Liao W, et al: MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2. Gastroenterology 144: 624-635.e4, 2013.
    • (2013) Gastroenterology , vol.144 , pp. 624-624e4
    • Liang, L.1    Li, X.2    Zhang, X.3    Lv, Z.4    He, G.5    Zhao, W.6    Ren, X.7    Li, Y.8    Bian, X.9    Liao, W.10
  • 192
    • 84873057723 scopus 로고    scopus 로고
    • The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer
    • Gao P, Xing AY, Zhou GY, Zhang TG, Zhang JP, Gao C, Li H and Shi DB: The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer. Oncogene 32: 491-501, 2013.
    • (2013) Oncogene , vol.32 , pp. 491-501
    • Gao, P.1    Xing, A.Y.2    Zhou, G.Y.3    Zhang, T.G.4    Zhang, J.P.5    Gao, C.6    Li, H.7    Shi, D.B.8
  • 193
    • 84892671741 scopus 로고    scopus 로고
    • MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha
    • Zhang H, Pu J, Qi T, Qi M, Yang C, Li S, Huang K, Zheng L and Tong Q: MicroRNA-145 inhibits the growth, invasion, metastasis and angiogenesis of neuroblastoma cells through targeting hypoxia-inducible factor 2 alpha. Oncogene 33: 387-397, 2014.
    • (2014) Oncogene , vol.33 , pp. 387-397
    • Zhang, H.1    Pu, J.2    Qi, T.3    Qi, M.4    Yang, C.5    Li, S.6    Huang, K.7    Zheng, L.8    Tong, Q.9
  • 194
    • 52149102044 scopus 로고    scopus 로고
    • Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells
    • Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J and Benz CC: Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene 27: 5643-5647, 2008.
    • (2008) Oncogene , vol.27 , pp. 5643-5647
    • Bhaumik, D.1    Scott, G.K.2    Schokrpur, S.3    Patil, C.K.4    Campisi, J.5    Benz, C.C.6
  • 195
    • 40449131878 scopus 로고    scopus 로고
    • Loss of miR146a function in hormone-refractory prostate cancer
    • Lin SL, Chiang A, Chang D and Ying SY: Loss of miR146a function in hormone-refractory prostate cancer. RNA 14: 417-424, 2008.
    • (2008) RNA , vol.14 , pp. 417-424
    • Lin, S.L.1    Chiang, A.2    Chang, D.3    Ying, S.Y.4
  • 196
    • 84905401527 scopus 로고    scopus 로고
    • MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling
    • Zhang JP, Zeng C, Xu L, Gong J, Fang JH and Zhuang SM: MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling. Oncogene 33: 4069-4076, 2014.
    • (2014) Oncogene , vol.33 , pp. 4069-4076
    • Zhang, J.P.1    Zeng, C.2    Xu, L.3    Gong, J.4    Fang, J.H.5    Zhuang, S.M.6
  • 197
    • 84874626235 scopus 로고    scopus 로고
    • MiR148b is a major coordinator of breast cancer progression in a relapseassociated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1
    • Cimino D, De Pittà C, Orso F, Zampini M, Casara S, Penna E, Quaglino E, Forni M, Damasco C, Pinatel E, et al: miR148b is a major coordinator of breast cancer progression in a relapseassociated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1. FASEB J 27: 1223-1235, 2013.
    • (2013) FASEB J , vol.27 , pp. 1223-1235
    • Cimino, D.1    De Pittà, C.2    Orso, F.3    Zampini, M.4    Casara, S.5    Penna, E.6    Quaglino, E.7    Forni, M.8    Damasco, C.9    Pinatel, E.10
  • 202
    • 84969984789 scopus 로고    scopus 로고
    • Long noncoding RNA MIR31HG exhibits oncogenic property in pancreatic ductal adenocarcinoma and is negatively regulated by miR193b
    • Nov 9, (Epub ahead of print)
    • Yang H, Liu P, Zhang J, Peng X, Lu Z, Yu S, Meng Y, Tong WM and Chen J: Long noncoding RNA MIR31HG exhibits oncogenic property in pancreatic ductal adenocarcinoma and is negatively regulated by miR193b. Oncogene: Nov 9, 2015 (Epub ahead of print).
    • (2015) Oncogene
    • Yang, H.1    Liu, P.2    Zhang, J.3    Peng, X.4    Lu, Z.5    Yu, S.6    Meng, Y.7    Tong, W.M.8    Chen, J.9
  • 203
    • 79960374570 scopus 로고    scopus 로고
    • MiR198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway
    • Tan S, Li R, Ding K, Lobie PE and Zhu T: miR198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway. FEBS Lett 585: 2229-2234, 2011.
    • (2011) FEBS Lett , vol.585 , pp. 2229-2234
    • Tan, S.1    Li, R.2    Ding, K.3    Lobie, P.E.4    Zhu, T.5
  • 204
    • 84889766586 scopus 로고    scopus 로고
    • A TrkB-STAT3-miR204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells
    • Bao W, Wang HH, Tian FJ, He XY, Qiu MT, Wang JY, Zhang HJ, Wang LH and Wan XP: A TrkB-STAT3-miR204-5p regulatory circuitry controls proliferation and invasion of endometrial carcinoma cells. Mol Cancer 12: 155, 2013.
    • (2013) Mol Cancer , vol.12 , pp. 155
    • Bao, W.1    Wang, H.H.2    Tian, F.J.3    He, X.Y.4    Qiu, M.T.5    Wang, J.Y.6    Zhang, H.J.7    Wang, L.H.8    Wan, X.P.9
  • 205
    • 84940063392 scopus 로고    scopus 로고
    • Decreased expression of MiRNA-204-5p contributes to glioma progression and promotes glioma cell growth, migration and invasion
    • Xia Z, Liu F, Zhang J and Liu L: Decreased expression of MiRNA-204-5p contributes to glioma progression and promotes glioma cell growth, migration and invasion. PLoS One 10: e0132399, 2015.
    • (2015) PLoS One , vol.10 , pp. e0132399
    • Xia, Z.1    Liu, F.2    Zhang, J.3    Liu, L.4
  • 207
    • 84951858398 scopus 로고    scopus 로고
    • Comprehensive gene and microRNA expression profiling reveals miR206 inhibits MET in lung cancer metastasis
    • Chen QY, Jiao DM, Yan L, Wu YQ, Hu HZ, Song J, Yan J, Wu LJ, Xu LQ and Shi JG: Comprehensive gene and microRNA expression profiling reveals miR206 inhibits MET in lung cancer metastasis. Mol Biosyst 11: 2290-2302, 2015.
    • (2015) Mol Biosyst , vol.11 , pp. 2290-2302
    • Chen, Q.Y.1    Jiao, D.M.2    Yan, L.3    Wu, Y.Q.4    Hu, H.Z.5    Song, J.6    Yan, J.7    Wu, L.J.8    Xu, L.Q.9    Shi, J.G.10
  • 208
    • 84904736686 scopus 로고    scopus 로고
    • Identification of microRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression
    • Chen DL, Wang ZQ, Zeng ZL, Wu WJ, Zhang DS, Luo HY, Wang F, Qiu MZ, Wang DS, Ren C, et al: Identification of microRNA-214 as a negative regulator of colorectal cancer liver metastasis by way of regulation of fibroblast growth factor receptor 1 expression. Hepatology 60: 598-609, 2014.
    • (2014) Hepatology , vol.60 , pp. 598-609
    • Chen, D.L.1    Wang, Z.Q.2    Zeng, Z.L.3    Wu, W.J.4    Zhang, D.S.5    Luo, H.Y.6    Wang, F.7    Qiu, M.Z.8    Wang, D.S.9    Ren, C.10
  • 209
    • 77950428314 scopus 로고    scopus 로고
    • MiR218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor
    • Tie J, Pan Y, Zhao L, Wu K, Liu J, Sun S, Guo X, Wang B, Gang Y, Zhang Y, et al: MiR218 inhibits invasion and metastasis of gastric cancer by targeting the Robo1 receptor. PLoS Genet 6: e1000879, 2010.
    • (2010) PLoS Genet , vol.6 , pp. e1000879
    • Tie, J.1    Pan, Y.2    Zhao, L.3    Wu, K.4    Liu, J.5    Sun, S.6    Guo, X.7    Wang, B.8    Gang, Y.9    Zhang, Y.10
  • 211
    • 84884742814 scopus 로고    scopus 로고
    • MicroRNA-302b suppresses cell proliferation by targeting EGFR in human hepatocellular carcinoma SMMC-7721 cells
    • Wang L, Yao J, Shi X, Hu L, Li Z, Song T and Huang C: MicroRNA-302b suppresses cell proliferation by targeting EGFR in human hepatocellular carcinoma SMMC-7721 cells. BMC Cancer 13: 448, 2013.
    • (2013) BMC Cancer , vol.13 , pp. 448
    • Wang, L.1    Yao, J.2    Shi, X.3    Hu, L.4    Li, Z.5    Song, T.6    Huang, C.7
  • 213
    • 70350233470 scopus 로고    scopus 로고
    • Metastamir: The field of metastasis-regulatory microRNA is spreading
    • Hurst DR, Edmonds MD and Welch DR: Metastamir: The field of metastasis-regulatory microRNA is spreading. Cancer Res 69: 7495-7498, 2009.
    • (2009) Cancer Res , vol.69 , pp. 7495-7498
    • Hurst, D.R.1    Edmonds, M.D.2    Welch, D.R.3
  • 216
    • 84878466503 scopus 로고    scopus 로고
    • MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met
    • Luo W, Huang B, Li Z, Li H, Sun L, Zhang Q, Qiu X and Wang E: MicroRNA-449a is downregulated in non-small cell lung cancer and inhibits migration and invasion by targeting c-Met. PLoS One 8: e64759, 2013.
    • (2013) PLoS One , vol.8 , pp. e64759
    • Luo, W.1    Huang, B.2    Li, Z.3    Li, H.4    Sun, L.5    Zhang, Q.6    Qiu, X.7    Wang, E.8
  • 218
    • 84905643970 scopus 로고    scopus 로고
    • MicroRNA-493 suppresses tumor growth, invasion and metastasis of lung cancer by regulating E2F1
    • Gu Y, Cheng Y, Song Y, Zhang Z, Deng M, Wang C, Zheng G and He Z: MicroRNA-493 suppresses tumor growth, invasion and metastasis of lung cancer by regulating E2F1. PLoS One 9: e102602, 2014.
    • (2014) PLoS One , vol.9 , pp. e102602
    • Gu, Y.1    Cheng, Y.2    Song, Y.3    Zhang, Z.4    Deng, M.5    Wang, C.6    Zheng, G.7    He, Z.8
  • 222
    • 84910677316 scopus 로고    scopus 로고
    • MiR545 inhibited pancreatic ductal adenocarcinoma growth by targeting RIG-I
    • Song B, Ji W, Guo S, Liu A, Jing W, Shao C, Li G and Jin G: miR545 inhibited pancreatic ductal adenocarcinoma growth by targeting RIG-I. FEBS Lett 588: 4375-4381, 2014.
    • (2014) FEBS Lett , vol.588 , pp. 4375-4381
    • Song, B.1    Ji, W.2    Guo, S.3    Liu, A.4    Jing, W.5    Shao, C.6    Li, G.7    Jin, G.8
  • 223
    • 84895536623 scopus 로고    scopus 로고
    • MicroRNA-545 suppresses cell proliferation by targeting cyclin D1 and CDK4 in lung cancer cells
    • Bowen D, Zhe W, Xin Z, Shipeng F, Guoxin W, Jianxing H and Zhang B: MicroRNA-545 suppresses cell proliferation by targeting cyclin D1 and CDK4 in lung cancer cells. PLoS 9: 88022, 2014.
    • (2014) PLoS , vol.9 , pp. 88022
    • Bowen, D.1    Zhe, W.2    Xin, Z.3    Shipeng, F.4    Guoxin, W.5    Jianxing, H.6    Zhang, B.7
  • 225
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs-microRNAs with a role in cancer
    • Esquela-Kerscher A and Slack FJ: Oncomirs-microRNAs with a role in cancer. Nat Rev Cancer 6: 259-269, 2006.
    • (2006) Nat Rev Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 229
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST and Patel T: MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology 133: 647-658, 2007.
    • (2007) Gastroenterology , vol.133 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 230
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • Zhu S, Si ML, Wu H and Mo YY: MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem 282: 14328-14336, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 231
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR21 in breast cancer cells
    • Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A and Lund AH: Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR21 in breast cancer cells. J Biol Chem 283: 1026-1033, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 235
    • 85027957315 scopus 로고    scopus 로고
    • The roles of microRNAs in the regulation of tumor metastasis
    • Zhou L, Liu F, Wang X and Ouyang G: The roles of microRNAs in the regulation of tumor metastasis. Cell Biosci 5: 32, 2015.
    • (2015) Cell Biosci , vol.5 , pp. 32
    • Zhou, L.1    Liu, F.2    Wang, X.3    Ouyang, G.4
  • 236
    • 84903301225 scopus 로고    scopus 로고
    • MicroRNA 25 promotes osteosarcoma cell proliferation by targeting the cell cycle inhibitor p27
    • Wang XH, Cai P, Wang MH and Wang Z: microRNA 25 promotes osteosarcoma cell proliferation by targeting the cell cycle inhibitor p27. Mol Med Rep 10: 855-859, 2014.
    • (2014) Mol Med Rep , vol.10 , pp. 855-859
    • Wang, X.H.1    Cai, P.2    Wang, M.H.3    Wang, Z.4
  • 237
    • 84940961003 scopus 로고    scopus 로고
    • Transforming growth factor-promotes prostate bone metastasis through induction of microRNA-96 and activation of the mTOR pathway
    • Siu MK, Tsai YC, Chang YS, Yin JJ, Suau F, Chen WY and Liu YN: Transforming growth factor-promotes prostate bone metastasis through induction of microRNA-96 and activation of the mTOR pathway. Oncogene 34: 4767-4776, 2015.
    • (2015) Oncogene , vol.34 , pp. 4767-4776
    • Siu, M.K.1    Tsai, Y.C.2    Chang, Y.S.3    Yin, J.J.4    Suau, F.5    Chen, W.Y.6    Liu, Y.N.7
  • 238
    • 84938884075 scopus 로고    scopus 로고
    • MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway
    • Xia X, Li Y, Wang W, Tang F, Tan J, Sun L, Li Q, Sun L, Tang B and He S: MicroRNA-1908 functions as a glioblastoma oncogene by suppressing PTEN tumor suppressor pathway. Mol Cancer 14: 154, 2015.
    • (2015) Mol Cancer , vol.14 , pp. 154
    • Xia, X.1    Li, Y.2    Wang, W.3    Tang, F.4    Tan, J.5    Sun, L.6    Li, Q.7    Sun, L.8    Tang, B.9    He, S.10
  • 240
    • 77950877531 scopus 로고    scopus 로고
    • MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines
    • Tian Y, Luo A, Cai Y, Su Q, Ding F, Chen H and Liu Z: MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines. J Biol Chem 285: 7986-7994, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 7986-7994
    • Tian, Y.1    Luo, A.2    Cai, Y.3    Su, Q.4    Ding, F.5    Chen, H.6    Liu, Z.7
  • 242
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM and Kosik KS: MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 65: 6029-6033, 2005.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 244
    • 84863992937 scopus 로고    scopus 로고
    • Androgen-regulated processing of the oncomir miR27a, which targets Prohibitin in prostate cancer
    • Fletcher CE, Dart DA, Sita-Lumsden A, Cheng H, Rennie PS and Bevan CL: Androgen-regulated processing of the oncomir miR27a, which targets Prohibitin in prostate cancer. Hum Mol Genet 21: 3112-3127, 2012.
    • (2012) Hum Mol Genet , vol.21 , pp. 3112-3127
    • Fletcher, C.E.1    Dart, D.A.2    Sita-Lumsden, A.3    Cheng, H.4    Rennie, P.S.5    Bevan, C.L.6
  • 245
    • 78049414216 scopus 로고    scopus 로고
    • Over-expression of miR100 is responsible for the low-expression of ATM in the human glioma cell line: M059J
    • Ng WL, Yan D, Zhang X, Mo YY and Wang Y: Over-expression of miR100 is responsible for the low-expression of ATM in the human glioma cell line: M059J. DNA Repair (Amst) 9: 1170-1175, 2010.
    • (2010) DNA Repair (Amst) , vol.9 , pp. 1170-1175
    • Ng, W.L.1    Yan, D.2    Zhang, X.3    Mo, Y.Y.4    Wang, Y.5
  • 246
    • 84855349331 scopus 로고    scopus 로고
    • MiR100 regulates cell differentiation and survival by targeting RBSP3, a phosphataselike tumor suppressor in acute myeloid leukemia
    • Zheng YS, Zhang H, Zhang XJ, Feng DD, Luo XQ, Zeng CW, Lin KY, Zhou H, Qu LH, Zhang P, et al: MiR100 regulates cell differentiation and survival by targeting RBSP3, a phosphataselike tumor suppressor in acute myeloid leukemia. Oncogene 31: 80-92, 2012.
    • (2012) Oncogene , vol.31 , pp. 80-92
    • Zheng, Y.S.1    Zhang, H.2    Zhang, X.J.3    Feng, D.D.4    Luo, X.Q.5    Zeng, C.W.6    Lin, K.Y.7    Zhou, H.8    Qu, L.H.9    Zhang, P.10
  • 249
    • 77952944048 scopus 로고    scopus 로고
    • MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer
    • Kong W, He L, Coppola M, Guo J, Esposito NN, Coppola D and Cheng JQ: MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. J Biol Chem 285: 17869-17879, 2010.
    • (2010) J Biol Chem , vol.285 , pp. 17869-17879
    • Kong, W.1    He, L.2    Coppola, M.3    Guo, J.4    Esposito, N.N.5    Coppola, D.6    Cheng, J.Q.7
  • 250
    • 77951026718 scopus 로고    scopus 로고
    • MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene
    • Jiang S, Zhang HW, Lu MH, He XH, Li Y, Gu H, Liu MF and Wang ED: MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene. Cancer Res 70: 3119-3127, 2010.
    • (2010) Cancer Res , vol.70 , pp. 3119-3127
    • Jiang, S.1    Zhang, H.W.2    Lu, M.H.3    He, X.H.4    Li, Y.5    Gu, H.6    Liu, M.F.7    Wang, E.D.8
  • 251
    • 84893745579 scopus 로고    scopus 로고
    • MiR155 at the heart of oncogenic pathways
    • Czyzyk-Krzeska MF and Zhang X: MiR155 at the heart of oncogenic pathways. Oncogene 33: 677-678, 2014.
    • (2014) Oncogene , vol.33 , pp. 677-678
    • Czyzyk-Krzeska, M.F.1    Zhang, X.2
  • 252
    • 84860312320 scopus 로고    scopus 로고
    • Role of miR155 in breast cancer
    • Wang J and Wu J: Role of miR155 in breast cancer. Front Biosci (Landmark Ed) 17: 2350-2355, 2012.
    • (2012) Front Biosci (Landmark Ed) , vol.17 , pp. 2350-2355
    • Wang, J.1    Wu, J.2
  • 253
    • 84885076418 scopus 로고    scopus 로고
    • MicroRNA-155 regulates cell proliferation and invasion by targeting FOXO3a in glioma
    • Ling N, Gu J, Lei Z, Li M, Zhao J, Zhang HT and Li X: microRNA-155 regulates cell proliferation and invasion by targeting FOXO3a in glioma. Oncol Rep 30: 2111-2118, 2013.
    • (2013) Oncol Rep , vol.30 , pp. 2111-2118
    • Ling, N.1    Gu, J.2    Lei, Z.3    Li, M.4    Zhao, J.5    Zhang, H.T.6    Li, X.7
  • 254
    • 84929268267 scopus 로고    scopus 로고
    • MicroRNAs in B-cell lymphomas: How a complex biology gets more complex
    • Musilova K and Mraz M: MicroRNAs in B-cell lymphomas: How a complex biology gets more complex. Leukemia 29: 1004-1017, 2015.
    • (2015) Leukemia , vol.29 , pp. 1004-1017
    • Musilova, K.1    Mraz, M.2
  • 259
  • 262
    • 85048836549 scopus 로고    scopus 로고
    • Role of MicroRNAs-221/222 in digestive systems
    • Matsuzaki J and Suzuki H: Role of MicroRNAs-221/222 in digestive systems. J Clin Med 4: 1566-1577, 2015.
    • (2015) J Clin Med , vol.4 , pp. 1566-1577
    • Matsuzaki, J.1    Suzuki, H.2
  • 266
    • 84904682519 scopus 로고    scopus 로고
    • Snail-regulated MiR375 inhibits migration and invasion of gastric cancer cells by targeting JAK2
    • Xu Y, Jin J, Liu Y, Huang Z, Deng Y, You T, Zhou T, Si J and Zhuo W: Snail-regulated MiR375 inhibits migration and invasion of gastric cancer cells by targeting JAK2. PLoS One 9: e99516, 2014.
    • (2014) PLoS One , vol.9 , pp. e99516
    • Xu, Y.1    Jin, J.2    Liu, Y.3    Huang, Z.4    Deng, Y.5    You, T.6    Zhou, T.7    Si, J.8    Zhuo, W.9
  • 267
    • 38049103266 scopus 로고    scopus 로고
    • MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression
    • Lee DY, Deng Z, Wang CH and Yang BB: MicroRNA-378 promotes cell survival, tumor growth, and angiogenesis by targeting SuFu and Fus-1 expression. Proc Natl Acad Sci USA 104: 20350-20355, 2007.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 20350-20355
    • Lee, D.Y.1    Deng, Z.2    Wang, C.H.3    Yang, B.B.4
  • 268
    • 84959018584 scopus 로고    scopus 로고
    • MicroRNA-519a promotes tumor growth by targeting PTEN/PI3K/AKT signaling in hepatocellular carcinoma
    • Tu K, Liu Z, Yao B, Han S and Yang W: MicroRNA-519a promotes tumor growth by targeting PTEN/PI3K/AKT signaling in hepatocellular carcinoma. Int J Oncol 48: 965-974, 2016.
    • (2016) Int J Oncol , vol.48 , pp. 965-974
    • Tu, K.1    Liu, Z.2    Yao, B.3    Han, S.4    Yang, W.5
  • 269
    • 84946818996 scopus 로고    scopus 로고
    • MicroRNA-519a promotes proliferation and inhibits apoptosis of hepatocellular carcinoma cells by targeting FOXF2
    • Shao J, Cao J, Liu Y, Mei H, Zhang Y and Xu W: MicroRNA-519a promotes proliferation and inhibits apoptosis of hepatocellular carcinoma cells by targeting FOXF2. FEBS Open Bio 5: 893-899, 2015.
    • (2015) FEBS Open Bio , vol.5 , pp. 893-899
    • Shao, J.1    Cao, J.2    Liu, Y.3    Mei, H.4    Zhang, Y.5    Xu, W.6
  • 270
    • 84904259547 scopus 로고    scopus 로고
    • MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumoursuppressor genes in ER+ breast cancer
    • Ward A, Shukla K, Balwierz A, Soons Z, König R, Sahin O and Wiemann S: MicroRNA-519a is a novel oncomir conferring tamoxifen resistance by targeting a network of tumoursuppressor genes in ER+ breast cancer. J Pathol 233: 368-379, 2014.
    • (2014) J Pathol , vol.233 , pp. 368-379
    • Ward, A.1    Shukla, K.2    Balwierz, A.3    Soons, Z.4    König, R.5    Sahin, O.6    Wiemann, S.7
  • 271
    • 77950881915 scopus 로고    scopus 로고
    • Oncofetal H19-derived miR675 regulates tumor suppressor RB in human colorectal cancer
    • Tsang WP, Ng EK, Ng SS, Jin H, Yu J, Sung JJ and Kwok TT: Oncofetal H19-derived miR675 regulates tumor suppressor RB in human colorectal cancer. Carcinogenesis 31: 350-358, 2010.
    • (2010) Carcinogenesis , vol.31 , pp. 350-358
    • Tsang, W.P.1    Ng, E.K.2    Ng, S.S.3    Jin, H.4    Yu, J.5    Sung, J.J.6    Kwok, T.T.7
  • 275
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • Ma L, Teruya-Feldstein J and Weinberg RA: Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449: 682-688, 2007.
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 276
    • 84870573000 scopus 로고    scopus 로고
    • MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme
    • Lin J, Teo S, Lam DH, Jeyaseelan K and Wang S: MicroRNA-10b pleiotropically regulates invasion, angiogenicity and apoptosis of tumor cells resembling mesenchymal subtype of glioblastoma multiforme. Cell Death Dis 3: e398, 2012.
    • (2012) Cell Death Dis , vol.3 , pp. e398
    • Lin, J.1    Teo, S.2    Lam, D.H.3    Jeyaseelan, K.4    Wang, S.5
  • 277
    • 84938081311 scopus 로고    scopus 로고
    • MiR15b promotes epithelial-mesenchymal transition by inhibiting SMURF2 in pancreatic cancer
    • Zhang WL, Zhang JH, Wu XZ, Yan T and Lv W: miR15b promotes epithelial-mesenchymal transition by inhibiting SMURF2 in pancreatic cancer. Int J Oncol 47: 1043-1053, 2015.
    • (2015) Int J Oncol , vol.47 , pp. 1043-1053
    • Zhang, W.L.1    Zhang, J.H.2    Wu, X.Z.3    Yan, T.4    Lv, W.5
  • 278
    • 84897388025 scopus 로고    scopus 로고
    • MiR19a/b modulate the metastasis of gastric cancer cells by targeting the tumour suppressor MXD1
    • Wu Q, Yang Z, An Y, Hu H, Yin J, Zhang P, Nie Y, Wu K, Shi Y and Fan D: MiR19a/b modulate the metastasis of gastric cancer cells by targeting the tumour suppressor MXD1. Cell Death Dis 5: e1144, 2014.
    • (2014) Cell Death Dis , vol.5 , pp. e1144
    • Wu, Q.1    Yang, Z.2    An, Y.3    Hu, H.4    Yin, J.5    Zhang, P.6    Nie, Y.7    Wu, K.8    Shi, Y.9    Fan, D.10
  • 280
    • 84925667016 scopus 로고    scopus 로고
    • MiR20a promotes cervical cancer proliferation and metastasis in vitro and in vivo
    • Zhao S, Yao D, Chen J, Ding N and Ren F: MiR20a promotes cervical cancer proliferation and metastasis in vitro and in vivo. PLoS One 10: e0120905, 2015.
    • (2015) PLoS One , vol.10 , pp. e0120905
    • Zhao, S.1    Yao, D.2    Chen, J.3    Ding, N.4    Ren, F.5
  • 281
    • 84922243138 scopus 로고    scopus 로고
    • Spatiotemporal dynamics of microRNA during epithelial collective cell migration
    • Dean ZS, Riahi R and Wong PK: Spatiotemporal dynamics of microRNA during epithelial collective cell migration. Biomaterials 37: 156-163, 2015.
    • (2015) Biomaterials , vol.37 , pp. 156-163
    • Dean, Z.S.1    Riahi, R.2    Wong, P.K.3
  • 283
    • 84928889340 scopus 로고    scopus 로고
    • Overexpression of miR21 promotes the proliferation and migration of cervical cancer cells via the inhibition of PTEN
    • Xu J, Zhang W, Lv Q and Zhu D: Overexpression of miR21 promotes the proliferation and migration of cervical cancer cells via the inhibition of PTEN. Oncol Rep 33: 3108-3116, 2015.
    • (2015) Oncol Rep , vol.33 , pp. 3108-3116
    • Xu, J.1    Zhang, W.2    Lv, Q.3    Zhu, D.4
  • 284
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S and Allgayer H: MicroRNA-21 (miR21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27: 2128-2136, 2008.
    • (2008) Oncogene , vol.27 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6    Allgayer, H.7
  • 285
    • 84933037647 scopus 로고    scopus 로고
    • MiR21: An environmental driver of malignant melanoma?
    • Melnik BC: MiR21: An environmental driver of malignant melanoma? J Transl Med 13: 202, 2015.
    • (2015) J Transl Med , vol.13 , pp. 202
    • Melnik, B.C.1
  • 290
    • 84893472501 scopus 로고    scopus 로고
    • TGF-upregulates miR182 expression to promote gallbladder cancer metastasis by targeting CADM1
    • Qiu Y, Luo X, Kan T, Zhang Y, Yu W, Wei Y, Shen N, Yi B and Jiang X: TGF-upregulates miR182 expression to promote gallbladder cancer metastasis by targeting CADM1. Mol Biosyst 10: 679-685, 2014.
    • (2014) Mol Biosyst , vol.10 , pp. 679-685
    • Qiu, Y.1    Luo, X.2    Kan, T.3    Zhang, Y.4    Yu, W.5    Wei, Y.6    Shen, N.7    Yi, B.8    Jiang, X.9
  • 291
    • 84922481074 scopus 로고    scopus 로고
    • MicroRNA-183 promotes proliferation and invasion in oesophageal squamous cell carcinoma by targeting programmed cell death 4
    • Ren LH, Chen WX, Li S, He XY, Zhang ZM, Li M, Cao RS, Hao B, Zhang HJ, Qiu HQ, et al: MicroRNA-183 promotes proliferation and invasion in oesophageal squamous cell carcinoma by targeting programmed cell death 4. Br J Cancer 111: 2003-2013, 2014.
    • (2014) Br J Cancer , vol.111 , pp. 2003-2013
    • Ren, L.H.1    Chen, W.X.2    Li, S.3    He, X.Y.4    Zhang, Z.M.5    Li, M.6    Cao, R.S.7    Hao, B.8    Zhang, H.J.9    Qiu, H.Q.10
  • 292
    • 47249091921 scopus 로고    scopus 로고
    • The miR200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2
    • Korpal M, Lee ES, Hu G and Kang Y: The miR200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2. J Biol Chem 283: 14910-14914, 2008.
    • (2008) J Biol Chem , vol.283 , pp. 14910-14914
    • Korpal, M.1    Lee, E.S.2    Hu, G.3    Kang, Y.4
  • 294
    • 41649091906 scopus 로고    scopus 로고
    • The miR200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2
    • Park SM, Gaur AB, Lengyel E and Peter ME: The miR200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2. Genes Dev 22: 894-907, 2008.
    • (2008) Genes Dev , vol.22 , pp. 894-907
    • Park, S.M.1    Gaur, A.B.2    Lengyel, E.3    Peter, M.E.4
  • 297
    • 84880048722 scopus 로고    scopus 로고
    • MiR214 coordinates melanoma progression by upregulating ALCAM through TFAP2 and miR148b downmodulation
    • Penna E, Orso F, Cimino D, Vercellino I, Grassi E, Quaglino E, Turco E and Taverna D: miR214 coordinates melanoma progression by upregulating ALCAM through TFAP2 and miR148b downmodulation. Cancer Res 73: 4098-4111, 2013.
    • (2013) Cancer Res , vol.73 , pp. 4098-4111
    • Penna, E.1    Orso, F.2    Cimino, D.3    Vercellino, I.4    Grassi, E.5    Quaglino, E.6    Turco, E.7    Taverna, D.8
  • 298
    • 84948799337 scopus 로고    scopus 로고
    • MicroRNA-214 promotes epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting the suppressorof-fused protein (Sufu)
    • Long H, Wang Z, Chen J, Xiang T, Li Q, Diao X and Zhu B: microRNA-214 promotes epithelial-mesenchymal transition and metastasis in lung adenocarcinoma by targeting the suppressorof-fused protein (Sufu). Oncotarget 6: 38705-38718, 2015.
    • (2015) Oncotarget , vol.6 , pp. 38705-38718
    • Long, H.1    Wang, Z.2    Chen, J.3    Xiang, T.4    Li, Q.5    Diao, X.6    Zhu, B.7
  • 299
    • 84889594198 scopus 로고    scopus 로고
    • MiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells
    • Liu X, Chen Q, Yan J, Wang Y, Zhu C, Chen C, Zhao X, Xu M, Sun Q, Deng R, et al: MiRNA-296-3p-ICAM-1 axis promotes metastasis of prostate cancer by possible enhancing survival of natural killer cell-resistant circulating tumour cells. Cell Death Dis 4: e928, 2013.
    • (2013) Cell Death Dis , vol.4 , pp. e928
    • Liu, X.1    Chen, Q.2    Yan, J.3    Wang, Y.4    Zhu, C.5    Chen, C.6    Zhao, X.7    Xu, M.8    Sun, Q.9    Deng, R.10
  • 301
    • 84919487219 scopus 로고    scopus 로고
    • MicroRNA-362-5p promotes tumor growth and metastasis by targeting CYLD in hepatocellular carcinoma
    • Ni F, Zhao H, Cui H, Wu Z, Chen L, Hu Z, Guo C, Liu Y, Chen Z, Wang X, et al: MicroRNA-362-5p promotes tumor growth and metastasis by targeting CYLD in hepatocellular carcinoma. Cancer Lett 356: 809-818, 2015.
    • (2015) Cancer Lett , vol.356 , pp. 809-818
    • Ni, F.1    Zhao, H.2    Cui, H.3    Wu, Z.4    Chen, L.5    Hu, Z.6    Guo, C.7    Liu, Y.8    Chen, Z.9    Wang, X.10
  • 302
    • 84946076051 scopus 로고    scopus 로고
    • MiR373 drives the epithelial-to-mesenchymal transition and metastasis via the miR373-TXNIP-HIF1-TWIST signaling axis in breast cancer
    • Chen D, Dang BL, Huang JZ, Chen M, Wu D, Xu ML, Li R and Yan GR: MiR373 drives the epithelial-to-mesenchymal transition and metastasis via the miR373-TXNIP-HIF1-TWIST signaling axis in breast cancer. Oncotarget 6: 32701-32712, 2015.
    • (2015) Oncotarget , vol.6 , pp. 32701-32712
    • Chen, D.1    Dang, B.L.2    Huang, J.Z.3    Chen, M.4    Wu, D.5    Xu, M.L.6    Li, R.7    Yan, G.R.8
  • 303
    • 84928396588 scopus 로고    scopus 로고
    • Dual functions of miR373 and miR520c by differently regulating the activities of MMP2 and MMP9
    • Lu S, Zhu Q, Zhang Y, Song W, Wilson MJ and Liu P: Dual functions of miR373 and miR520c by differently regulating the activities of MMP2 and MMP9. J Cell Physiol 230: 1862-1870, 2015.
    • (2015) J Cell Physiol , vol.230 , pp. 1862-1870
    • Lu, S.1    Zhu, Q.2    Zhang, Y.3    Song, W.4    Wilson, M.J.5    Liu, P.6
  • 306
    • 84879403677 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor signaling by plasmid-based microRNA-7 inhibits human malignant gliomas growth and metastasis in vivo
    • Wang W, Dai LX, Zhang S, Yang Y, Yan N, Fan P, Dai L, Tian HW, Cheng L, Zhang XM, et al: Regulation of epidermal growth factor receptor signaling by plasmid-based microRNA-7 inhibits human malignant gliomas growth and metastasis in vivo. Neoplasma 60: 274-283, 2013.
    • (2013) Neoplasma , vol.60 , pp. 274-283
    • Wang, W.1    Dai, L.X.2    Zhang, S.3    Yang, Y.4    Yan, N.5    Fan, P.6    Dai, L.7    Tian, H.W.8    Cheng, L.9    Zhang, X.M.10
  • 308
    • 84962208468 scopus 로고    scopus 로고
    • MicroRNA-708-5p acts as a therapeutic agent against metastatic lung cancer
    • Wu X, Liu T, Fang O, Dong W, Zhang F, Leach L, Hu X and Luo Z: MicroRNA-708-5p acts as a therapeutic agent against metastatic lung cancer. Oncotarget 7: 2417-2432, 2016.
    • (2016) Oncotarget , vol.7 , pp. 2417-2432
    • Wu, X.1    Liu, T.2    Fang, O.3    Dong, W.4    Zhang, F.5    Leach, L.6    Hu, X.7    Luo, Z.8
  • 309
    • 84877648915 scopus 로고    scopus 로고
    • AntagomiR27a targets FOXO3a in glioblastoma and suppresses U87 cell growth in vitro and in vivo
    • Ge YF, Sun J, Jin CJ, Cao BQ, Jiang ZF and Shao JF: AntagomiR27a targets FOXO3a in glioblastoma and suppresses U87 cell growth in vitro and in vivo. Asian Pac J Cancer Prev 14: 963-968, 2013.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 963-968
    • Ge, Y.F.1    Sun, J.2    Jin, C.J.3    Cao, B.Q.4    Jiang, Z.F.5    Shao, J.F.6
  • 310
    • 79956032374 scopus 로고    scopus 로고
    • Targeting oncogenic miR335 inhibits growth and invasion of malignant astrocytoma cells
    • Shu M, Zheng X, Wu S, Lu H, Leng T, Zhu W, Zhou Y, Ou Y, Lin X, Lin Y, et al: Targeting oncogenic miR335 inhibits growth and invasion of malignant astrocytoma cells. Mol Cancer 10: 59, 2011.
    • (2011) Mol Cancer , vol.10 , pp. 59
    • Shu, M.1    Zheng, X.2    Wu, S.3    Lu, H.4    Leng, T.5    Zhu, W.6    Zhou, Y.7    Ou, Y.8    Lin, X.9    Lin, Y.10
  • 311
    • 84872058567 scopus 로고    scopus 로고
    • Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: Implications for cancer therapeutics
    • Rather MI, Nagashri MN, Swamy SS, Gopinath KS and Kumar A: Oncogenic microRNA-155 down-regulates tumor suppressor CDC73 and promotes oral squamous cell carcinoma cell proliferation: Implications for cancer therapeutics. J Biol Chem 288: 608-618, 2013.
    • (2013) J Biol Chem , vol.288 , pp. 608-618
    • Rather, M.I.1    Nagashri, M.N.2    Swamy, S.S.3    Gopinath, K.S.4    Kumar, A.5
  • 316
    • 84949097148 scopus 로고    scopus 로고
    • Antisense inhibition of microRNA-21 and microRNA-221 in tumorinitiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer
    • Zhao Y, Zhao L, Ischenko I, Bao Q, Schwarz B, Nieß H, Wang Y, Renner A, Mysliwietz J, Jauch KW, et al: Antisense inhibition of microRNA-21 and microRNA-221 in tumorinitiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer. Target Oncol 10: 535-548, 2015.
    • (2015) Target Oncol , vol.10 , pp. 535-548
    • Zhao, Y.1    Zhao, L.2    Ischenko, I.3    Bao, Q.4    Schwarz, B.5    Nieß, H.6    Wang, Y.7    Renner, A.8    Mysliwietz, J.9    Jauch, K.W.10
  • 321
    • 84868000009 scopus 로고    scopus 로고
    • MicroRNA control of epithelial-mesenchymal transition and metastasis
    • Zhang J and Ma L: MicroRNA control of epithelial-mesenchymal transition and metastasis. Cancer Metastasis Rev 31: 653-662, 2012.
    • (2012) Cancer Metastasis Rev , vol.31 , pp. 653-662
    • Zhang, J.1    Ma, L.2
  • 322
    • 84863724654 scopus 로고    scopus 로고
    • Expression of miRNAs involved in angiogenesis, tumor cell proliferation, tumor suppressor inhibition, epithelial-mesenchymal transition and activation of metastasis in bladder cancer
    • Zaravinos A, Radojicic J, Lambrou GI, Volanis D, Delakas D, Stathopoulos EN and Spandidos DA: Expression of miRNAs involved in angiogenesis, tumor cell proliferation, tumor suppressor inhibition, epithelial-mesenchymal transition and activation of metastasis in bladder cancer. J Urol 188: 615-623, 2012.
    • (2012) J Urol , vol.188 , pp. 615-623
    • Zaravinos, A.1    Radojicic, J.2    Lambrou, G.I.3    Volanis, D.4    Delakas, D.5    Stathopoulos, E.N.6    Spandidos, D.A.7
  • 323
    • 84876515764 scopus 로고    scopus 로고
    • Epigenetic control of epithelial-mesenchymal-transition in human cancer
    • Kiesslich T, Pichler M and Neureiter D: Epigenetic control of epithelial-mesenchymal-transition in human cancer. Mol Clin Oncol 1: 3-11, 2013.
    • (2013) Mol Clin Oncol , vol.1 , pp. 3-11
    • Kiesslich, T.1    Pichler, M.2    Neureiter, D.3
  • 324
    • 84871439027 scopus 로고    scopus 로고
    • Up-regulated miR155 reverses the epithelial-mesenchymal transition induced by EGF and increases chemo-sensitivity to cisplatin in human Caski cervical cancer cells
    • Lei C, Wang Y, Huang Y, Yu H, Huang Y, Wu L and Huang L: Up-regulated miR155 reverses the epithelial-mesenchymal transition induced by EGF and increases chemo-sensitivity to cisplatin in human Caski cervical cancer cells. PLoS One 7: e52310, 2012.
    • (2012) PLoS One , vol.7 , pp. e52310
    • Lei, C.1    Wang, Y.2    Huang, Y.3    Yu, H.4    Huang, Y.5    Wu, L.6    Huang, L.7
  • 325
    • 84904763687 scopus 로고    scopus 로고
    • Epithelialmesenchymal transition-associated miRNAs in ovarian carcinoma, with highlight on the miR200 family: Prognostic value and prospective role in ovarian cancer therapeutics
    • Koutsaki M, Spandidos DA and Zaravinos A: Epithelialmesenchymal transition-associated miRNAs in ovarian carcinoma, with highlight on the miR200 family: Prognostic value and prospective role in ovarian cancer therapeutics. Cancer Lett 351: 173-181, 2014.
    • (2014) Cancer Lett , vol.351 , pp. 173-181
    • Koutsaki, M.1    Spandidos, D.A.2    Zaravinos, A.3
  • 327
    • 84866788059 scopus 로고    scopus 로고
    • Correlation between Slug transcription factor and miR221 in MDA-MB-231 breast cancer cells
    • Lambertini E, Lolli A, Vezzali F, Penolazzi L, Gambari R and Piva R: Correlation between Slug transcription factor and miR221 in MDA-MB-231 breast cancer cells. BMC Cancer 12: 445, 2012.
    • (2012) BMC Cancer , vol.12 , pp. 445
    • Lambertini, E.1    Lolli, A.2    Vezzali, F.3    Penolazzi, L.4    Gambari, R.5    Piva, R.6
  • 328
    • 84930927776 scopus 로고    scopus 로고
    • MiR139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2
    • Qiu G, Lin Y, Zhang H and Wu D: miR139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2. Biochem Biophys Res Commun 463: 315-321, 2015.
    • (2015) Biochem Biophys Res Commun , vol.463 , pp. 315-321
    • Qiu, G.1    Lin, Y.2    Zhang, H.3    Wu, D.4
  • 329
    • 82755162139 scopus 로고    scopus 로고
    • Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells
    • Bezzerri V, Borgatti M, Finotti A, Tamanini A, Gambari R and Cabrini G: Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells. J Immunol 187: 6069-6081, 2011.
    • (2011) J Immunol , vol.187 , pp. 6069-6081
    • Bezzerri, V.1    Borgatti, M.2    Finotti, A.3    Tamanini, A.4    Gambari, R.5    Cabrini, G.6
  • 330
    • 78651265055 scopus 로고    scopus 로고
    • IL-8 is a mediator of NF-B induced invasion by gliomas
    • Raychaudhuri B and Vogelbaum MA: IL-8 is a mediator of NF-B induced invasion by gliomas. J Neurooncol 101: 227-235, 2011.
    • (2011) J Neurooncol , vol.101 , pp. 227-235
    • Raychaudhuri, B.1    Vogelbaum, M.A.2
  • 331
    • 77349094234 scopus 로고    scopus 로고
    • Constitutive NF-B activity regulates the expression of VEGF and IL-8 and tumor angiogenesis of human glioblastoma
    • Xie TX, Xia Z, Zhang N, Gong W and Huang S: Constitutive NF-B activity regulates the expression of VEGF and IL-8 and tumor angiogenesis of human glioblastoma. Oncol Rep 23: 725-732, 2010.
    • (2010) Oncol Rep , vol.23 , pp. 725-732
    • Xie, T.X.1    Xia, Z.2    Zhang, N.3    Gong, W.4    Huang, S.5
  • 332
    • 78651275992 scopus 로고    scopus 로고
    • Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-B
    • Sun S, Wang Q, Giang A, Cheng C, Soo C, Wang CY, Liau LM and Chiu R: Knockdown of CypA inhibits interleukin-8 (IL-8) and IL-8-mediated proliferation and tumor growth of glioblastoma cells through down-regulated NF-B. J Neurooncol 101: 1-14, 2011.
    • (2011) J Neurooncol , vol.101 , pp. 1-14
    • Sun, S.1    Wang, Q.2    Giang, A.3    Cheng, C.4    Soo, C.5    Wang, C.Y.6    Liau, L.M.7    Chiu, R.8
  • 333
    • 53749105340 scopus 로고    scopus 로고
    • Involvement of nuclear factor-kappa B in bcl-xL-induced interleukin 8 expression in glioblastoma
    • Gabellini C, Castellini L, Trisciuoglio D, Kracht M, Zupi G and Del Bufalo D: Involvement of nuclear factor-kappa B in bcl-xL-induced interleukin 8 expression in glioblastoma. J Neurochem 107: 871-882, 2008.
    • (2008) J Neurochem , vol.107 , pp. 871-882
    • Gabellini, C.1    Castellini, L.2    Trisciuoglio, D.3    Kracht, M.4    Zupi, G.5    Del Bufalo, D.6
  • 334
    • 84895529094 scopus 로고    scopus 로고
    • MicroRNA-16 inhibits glioma cell growth and invasion through suppression of BCL2 and the nuclear factor-B1/MMP9 signaling pathway
    • Yang TQ, Lu XJ, Wu TF, Ding DD, Zhao ZH, Chen GL, Xie XS, Li B, Wei YX, Guo LC, et al: MicroRNA-16 inhibits glioma cell growth and invasion through suppression of BCL2 and the nuclear factor-B1/MMP9 signaling pathway. Cancer Sci 105: 265-271, 2014.
    • (2014) Cancer Sci , vol.105 , pp. 265-271
    • Yang, T.Q.1    Lu, X.J.2    Wu, T.F.3    Ding, D.D.4    Zhao, Z.H.5    Chen, G.L.6    Xie, X.S.7    Li, B.8    Wei, Y.X.9    Guo, L.C.10
  • 336
    • 65849172454 scopus 로고    scopus 로고
    • Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumors
    • Magge SN, Malik SZ, Royo NC, Chen HI, Yu L, Snyder EY, O'Rourke DM and Watson DJ: Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumors. J Neurosci Res 87: 1547-1555, 2009.
    • (2009) J Neurosci Res , vol.87 , pp. 1547-1555
    • Magge, S.N.1    Malik, S.Z.2    Royo, N.C.3    Chen, H.I.4    Yu, L.5    Snyder, E.Y.6    O'Rourke, D.M.7    Watson, D.J.8
  • 338
    • 84954070041 scopus 로고    scopus 로고
    • MiR124 suppresses the migration and invasion of glioma cells in vitro via Capn4
    • Cai JJ, Qi ZX, Chen LC, Yao Y and Gong Y and Mao Y: miR124 suppresses the migration and invasion of glioma cells in vitro via Capn4. Oncol Rep 35: 284-290, 2015.
    • (2015) Oncol Rep , vol.35 , pp. 284-290
    • Cai, J.J.1    Qi, Z.X.2    Chen, L.C.3    Yao, Y.4    Gong, Y.5    Mao, Y.6
  • 339
    • 84933036063 scopus 로고    scopus 로고
    • STAT3 is involved in miR124-mediated suppressive effects on esophageal cancer cells
    • Cheng Y, Li Y, Nian Y, Liu D, Dai F and Zhang J: STAT3 is involved in miR124-mediated suppressive effects on esophageal cancer cells. BMC Cancer 15: 306, 2015.
    • (2015) BMC Cancer , vol.15 , pp. 306
    • Cheng, Y.1    Li, Y.2    Nian, Y.3    Liu, D.4    Dai, F.5    Zhang, J.6
  • 340
    • 84939265676 scopus 로고    scopus 로고
    • Decreased expression of microRNA-124 is an independent unfavorable prognostic factor for patients with breast cancer
    • Dong LL, Chen LM, Wang WM, Zhang LM: Decreased expression of microRNA-124 is an independent unfavorable prognostic factor for patients with breast cancer. Diagn Pathol 10: 45, 2015.
    • (2015) Diagn Pathol , vol.10 , pp. 45
    • Dong, L.L.1    Chen, L.M.2    Wang, W.M.3    Zhang, L.M.4
  • 341
    • 84947127053 scopus 로고    scopus 로고
    • MiR124 represses FZD5 to attenuate P-glycoprotein-mediated chemo-resistance in renal cell carcinoma
    • Long QZ, Du YF, Liu XG, Li X and He DL: miR124 represses FZD5 to attenuate P-glycoprotein-mediated chemo-resistance in renal cell carcinoma. Tumour Biol 36: 7017-7026, 2015.
    • (2015) Tumour Biol , vol.36 , pp. 7017-7026
    • Long, Q.Z.1    Du, Y.F.2    Liu, X.G.3    Li, X.4    He, D.L.5
  • 342
    • 84907289380 scopus 로고    scopus 로고
    • MiR124a restoration inhibits glioma cell proliferation and invasion by suppressing IQGAP1 and-catenin
    • Lu SH, Jiang XJ, Xiao GL, Liu DY and Yuan XR: miR124a restoration inhibits glioma cell proliferation and invasion by suppressing IQGAP1 and-catenin. Oncol Rep 32: 2104-2110, 2014.
    • (2014) Oncol Rep , vol.32 , pp. 2104-2110
    • Lu, S.H.1    Jiang, X.J.2    Xiao, G.L.3    Liu, D.Y.4    Yuan, X.R.5
  • 346
    • 34548168073 scopus 로고    scopus 로고
    • MiR221 and miR222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1
    • Galardi S, Mercatelli N, Giorda E, Massalini S, Frajese GV, Ciafrè SA and Farace MG: miR221 and miR222 expression affects the proliferation potential of human prostate carcinoma cell lines by targeting p27Kip1. J Biol Chem 282: 23716-23724, 2007.
    • (2007) J Biol Chem , vol.282 , pp. 23716-23724
    • Galardi, S.1    Mercatelli, N.2    Giorda, E.3    Massalini, S.4    Frajese, G.V.5    Ciafrè, S.A.6    Farace, M.G.7
  • 348
    • 34548268220 scopus 로고    scopus 로고
    • Regulation of p27Kip1 by miRNA 221/222 in glioblastoma
    • Gillies JK and Lorimer IA: Regulation of p27Kip1 by miRNA 221/222 in glioblastoma. Cell Cycle 6: 2005-2009, 2007.
    • (2007) Cell Cycle , vol.6 , pp. 2005-2009
    • Gillies, J.K.1    Lorimer, I.A.2
  • 353
    • 84899796183 scopus 로고    scopus 로고
    • Down-regulation of miR221 inhibits proliferation of pancreatic cancer cells through up-regulation of PTEN, p27(kip1), p57(kip2), and PUMA
    • Sarkar S, Dubaybo H, Ali S, Goncalves P, Kollepara SL, Sethi S, Philip PA and Li Y: Down-regulation of miR221 inhibits proliferation of pancreatic cancer cells through up-regulation of PTEN, p27(kip1), p57(kip2), and PUMA. Am J Cancer Res 3: 465-477, 2013.
    • (2013) Am J Cancer Res , vol.3 , pp. 465-477
    • Sarkar, S.1    Dubaybo, H.2    Ali, S.3    Goncalves, P.4    Kollepara, S.L.5    Sethi, S.6    Philip, P.A.7    Li, Y.8
  • 354
    • 67649424199 scopus 로고    scopus 로고
    • Co-suppression of miR221/222 cluster suppresses human glioma cell growth by targeting p27Kip1 in vitro and in vivo
    • Zhang C, Kang C, You Y, Pu P, Yang W, Zhao P, Wang G, Zhang A, Jia Z, Han L, et al: Co-suppression of miR221/222 cluster suppresses human glioma cell growth by targeting p27Kip1 in vitro and in vivo. Int J Oncol 34: 1653-1660, 2009.
    • (2009) Int J Oncol , vol.34 , pp. 1653-1660
    • Zhang, C.1    Kang, C.2    You, Y.3    Pu, P.4    Yang, W.5    Zhao, P.6    Wang, G.7    Zhang, A.8    Jia, Z.9    Han, L.10
  • 355
    • 84961185203 scopus 로고    scopus 로고
    • Plasma miR-221/222 family as novel descriptive and prognostic biomarkers for glioma
    • Zhang R, Pang B, Xin T, Guo H, Xing Y, Xu S, Feng B, Liu B and Pang Q: Plasma miR-221/222 family as novel descriptive and prognostic biomarkers for glioma. Mol Neurobiol 53: 1452-1460, 2016.
    • (2016) Mol Neurobiol , vol.53 , pp. 1452-1460
    • Zhang, R.1    Pang, B.2    Xin, T.3    Guo, H.4    Xing, Y.5    Xu, S.6    Feng, B.7    Liu, B.8    Pang, Q.9
  • 356
    • 84930381842 scopus 로고    scopus 로고
    • MiR137/197 induce apoptosis and suppress tumorigenicity by targeting MCL-1 in multiple myeloma
    • Yang Y, Li F, Saha MN, Abdi J, Qiu L and Chang H: miR137/197 induce apoptosis and suppress tumorigenicity by targeting MCL-1 in multiple myeloma. Clin Cancer Res 21: 2399-2411, 2015.
    • (2015) Clin Cancer Res , vol.21 , pp. 2399-2411
    • Yang, Y.1    Li, F.2    Saha, M.N.3    Abdi, J.4    Qiu, L.5    Chang, H.6
  • 357
    • 84946053153 scopus 로고    scopus 로고
    • Targeting of RUNX3 by miR130a and miR495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells
    • Lee SH, Jung YD, Choi YS and Lee YM: Targeting of RUNX3 by miR130a and miR495 cooperatively increases cell proliferation and tumor angiogenesis in gastric cancer cells. Oncotarget 6: 33269-33278, 2015.
    • (2015) Oncotarget , vol.6 , pp. 33269-33278
    • Lee, S.H.1    Jung, Y.D.2    Choi, Y.S.3    Lee, Y.M.4
  • 360
    • 84910609183 scopus 로고    scopus 로고
    • MiR200c sensitizes clear-cell renal cell carcinoma cells to sorafenib and imatinib by targeting heme oxygenase-1
    • Gao C, Peng FH and Peng LK: MiR200c sensitizes clear-cell renal cell carcinoma cells to sorafenib and imatinib by targeting heme oxygenase-1. Neoplasma 61: 680-689, 2014.
    • (2014) Neoplasma , vol.61 , pp. 680-689
    • Gao, C.1    Peng, F.H.2    Peng, L.K.3
  • 361
    • 77956995581 scopus 로고    scopus 로고
    • Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
    • Pogribny IP, Filkowski JN, Tryndyak VP, Golubov A, Shpyleva SI and Kovalchuk O: Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. Int J Cancer 127: 1785-1794, 2010.
    • (2010) Int J Cancer , vol.127 , pp. 1785-1794
    • Pogribny, I.P.1    Filkowski, J.N.2    Tryndyak, V.P.3    Golubov, A.4    Shpyleva, S.I.5    Kovalchuk, O.6
  • 362
  • 364
    • 84961590034 scopus 로고    scopus 로고
    • MiR143 or miR145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells
    • Jan 25, (Epub ahead of print)
    • Gomes SE, Simões AE, Pereira DM, Castro RE, Rodrigues CM and Borralho PM: miR143 or miR145 overexpression increases cetuximab-mediated antibody-dependent cellular cytotoxicity in human colon cancer cells. Oncotarget: Jan 25, 2016 (Epub ahead of print).
    • (2016) Oncotarget
    • Gomes, S.E.1    Simões, A.E.2    Pereira, D.M.3    Castro, R.E.4    Rodrigues, C.M.5    Borralho, P.M.6
  • 366
    • 84865988896 scopus 로고    scopus 로고
    • Sequence-dependent synergistic inhibition of human glioma cell lines by combined temozolomide and miR21 inhibitor gene therapy
    • Qian X, Ren Y, Shi Z, Long L, Pu P, Sheng J, Yuan X and Kang C: Sequence-dependent synergistic inhibition of human glioma cell lines by combined temozolomide and miR21 inhibitor gene therapy. Mol Pharm 9: 2636-2645, 2012.
    • (2012) Mol Pharm , vol.9 , pp. 2636-2645
    • Qian, X.1    Ren, Y.2    Shi, Z.3    Long, L.4    Pu, P.5    Sheng, J.6    Yuan, X.7    Kang, C.8
  • 367
    • 84923095860 scopus 로고    scopus 로고
    • Combination treatment with doxorubicin and microRNA-21 inhibitor synergistically augments anticancer activity through upregulation of tumor suppressing genes
    • Zhang S, Han L, Wei J, Shi Z, Pu P, Zhang J, Yuan X and Kang C: Combination treatment with doxorubicin and microRNA-21 inhibitor synergistically augments anticancer activity through upregulation of tumor suppressing genes. Int J Oncol 46: 1589-1600, 2015.
    • (2015) Int J Oncol , vol.46 , pp. 1589-1600
    • Zhang, S.1    Han, L.2    Wei, J.3    Shi, Z.4    Pu, P.5    Zhang, J.6    Yuan, X.7    Kang, C.8
  • 368
    • 84919387496 scopus 로고    scopus 로고
    • Simultaneous delivery of therapeutic antagomirs with paclitaxel for the management of metastatic tumors by a pH-responsive anti-microbial peptide-mediated liposomal delivery system
    • Zhang Q, Ran R, Zhang L, Liu Y, Mei L, Zhang Z, Gao H and He Q: Simultaneous delivery of therapeutic antagomirs with paclitaxel for the management of metastatic tumors by a pH-responsive anti-microbial peptide-mediated liposomal delivery system. J Control Release 197: 208-218, 2015.
    • (2015) J Control Release , vol.197 , pp. 208-218
    • Zhang, Q.1    Ran, R.2    Zhang, L.3    Liu, Y.4    Mei, L.5    Zhang, Z.6    Gao, H.7    He, Q.8
  • 369
    • 84942328927 scopus 로고    scopus 로고
    • Dual loading miR218 mimics and Temozolomide using AuCOOH@FA-CS drug delivery system: Promising targeted anti-tumor drug delivery system with sequential release functions
    • Fan L, Yang Q, Tan J, Qiao Y, Wang Q, He J, Wu H and Zhang Y: Dual loading miR218 mimics and Temozolomide using AuCOOH@FA-CS drug delivery system: Promising targeted anti-tumor drug delivery system with sequential release functions. J Exp Clin Cancer Res 34: 106, 2015.
    • (2015) J Exp Clin Cancer Res , vol.34 , pp. 106
    • Fan, L.1    Yang, Q.2    Tan, J.3    Qiao, Y.4    Wang, Q.5    He, J.6    Wu, H.7    Zhang, Y.8
  • 372
    • 84880596133 scopus 로고    scopus 로고
    • The effect of Bcl-2 siRNA combined with miR15a oligonucleotides on the growth of Raji cells
    • Hu X, Li W, Liu G, Wu H, Gao Y, Chen S, He D and Zhang Y: The effect of Bcl-2 siRNA combined with miR15a oligonucleotides on the growth of Raji cells. Med Oncol 30: 430, 2013.
    • (2013) Med Oncol , vol.30 , pp. 430
    • Hu, X.1    Li, W.2    Liu, G.3    Wu, H.4    Gao, Y.5    Chen, S.6    He, D.7    Zhang, Y.8


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