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Volumn 32, Issue 11, 2014, Pages 2858-2868

MiR-7, inhibited indirectly by LincRNA HOTAIR, directly inhibits SETDB1 and reverses the EMT of breast cancer stem cells by downregulating the STAT3 pathway

Author keywords

Breast cancer stem cells; Epithelial mesenchymal transition; miR 7; SETDB1; Signal transducers and activators of transcription 3

Indexed keywords

HOTAIR LONG UNTRANSLATED RNA, HUMAN; MICRORNAS; MIRN7 MICRORNA, HUMAN; PROTEIN METHYLTRANSFERASES; RNA, LONG NONCODING; SETDB1 PROTEIN, HUMAN; STAT3 PROTEIN, HUMAN; STAT3 TRANSCRIPTION FACTOR;

EID: 84907895333     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1795     Document Type: Article
Times cited : (312)

References (47)
  • 2
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer CL, Weinberg RA,. A perspective on cancer cell metastasis. Science 2011; 331: 1559-1564.
    • (2011) Science , vol.331 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 3
    • 84861345640 scopus 로고    scopus 로고
    • MicroRNA-mediated breast cancer metastasis: From primary site to distant organs
    • Wang L, Wang J,. MicroRNA-mediated breast cancer metastasis: From primary site to distant organs. Oncogene 2012; 31: 2499-2511.
    • (2012) Oncogene , vol.31 , pp. 2499-2511
    • Wang, L.1    Wang, J.2
  • 4
    • 0037388204 scopus 로고    scopus 로고
    • Prospective identification of tumorigenic breast cancer cells
    • Al-Hajj M, Wicha MS, Benito-Hernandez A, et al. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 2003; 100: 3983-3988.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 3983-3988
    • Al-Hajj, M.1    Wicha, M.S.2    Benito-Hernandez, A.3
  • 5
    • 74949129868 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer
    • Charafe-Jauffret E, Ginestier C, Iovino F, et al. Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res 2010; 16: 45-55.
    • (2010) Clin Cancer Res , vol.16 , pp. 45-55
    • Charafe-Jauffret, E.1    Ginestier, C.2    Iovino, F.3
  • 6
    • 84862252744 scopus 로고    scopus 로고
    • A preliminary investigation of the relationship between circulating tumor cells and cancer stem cells in patients with breast cancer
    • Wang J, Cao MG, You CZ, et al. A preliminary investigation of the relationship between circulating tumor cells and cancer stem cells in patients with breast cancer. Cell Mol Biol 2012; 58 Suppl: OL1641-1645.
    • (2012) Cell Mol Biol , vol.58 , pp. OL1641-OL1645
    • Wang, J.1    Cao, M.G.2    You, C.Z.3
  • 7
    • 48349083393 scopus 로고    scopus 로고
    • Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity
    • Hughes L, Malone C, Chumsri S, et al. Characterisation of breast cancer cell lines and establishment of a novel isogenic subclone to study migration, invasion and tumourigenicity. Clin Exp Metastasis 2008; 25: 549-557.
    • (2008) Clin Exp Metastasis , vol.25 , pp. 549-557
    • Hughes, L.1    Malone, C.2    Chumsri, S.3
  • 8
    • 78149243774 scopus 로고    scopus 로고
    • Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation
    • Louie E, Nik S, Chen JS, et al. Identification of a stem-like cell population by exposing metastatic breast cancer cell lines to repetitive cycles of hypoxia and reoxygenation. Breast Cancer Res 2010; 12: R94.
    • (2010) Breast Cancer Res , vol.12 , pp. R94
    • Louie, E.1    Nik, S.2    Chen, J.S.3
  • 9
    • 84866324123 scopus 로고    scopus 로고
    • Cancer stem cells and epithelial-mesenchymal transition: Concepts and molecular links
    • Scheel C, Weinberg RA,. Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links. Semin Cancer Biol 2012; 22: 396-403.
    • (2012) Semin Cancer Biol , vol.22 , pp. 396-403
    • Scheel, C.1    Weinberg, R.A.2
  • 10
    • 84865973282 scopus 로고    scopus 로고
    • An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state
    • Polytarchou C, Iliopoulos D, Struhl K,. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proc Natl Acad Sci USA 2012; 109: 14470-14475.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 14470-14475
    • Polytarchou, C.1    Iliopoulos, D.2    Struhl, K.3
  • 11
    • 77954646313 scopus 로고    scopus 로고
    • Emerging strategies for the identification and targeting of cancer stem cells
    • Dou J, Gu N,. Emerging strategies for the identification and targeting of cancer stem cells. Tumour Biol 2010; 31: 243-253.
    • (2010) Tumour Biol , vol.31 , pp. 243-253
    • Dou, J.1    Gu, N.2
  • 12
    • 79953645921 scopus 로고    scopus 로고
    • Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: Induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a
    • Oliveras-Ferraros C, Cufi S, Vazquez-Martin A, et al. Micro(mi)RNA expression profile of breast cancer epithelial cells treated with the anti-diabetic drug metformin: induction of the tumor suppressor miRNA let-7a and suppression of the TGFbeta-induced oncomiR miRNA-181a. Cell Cycle 2011; 10: 1144-1151.
    • (2011) Cell Cycle , vol.10 , pp. 1144-1151
    • Oliveras-Ferraros, C.1    Cufi, S.2    Vazquez-Martin, A.3
  • 13
    • 84874324849 scopus 로고    scopus 로고
    • MiR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4
    • Okuda H, Xing F, Pandey PR, et al. miR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4. Cancer Res 2013; 73: 1434-1444.
    • (2013) Cancer Res , vol.73 , pp. 1434-1444
    • Okuda, H.1    Xing, F.2    Pandey, P.R.3
  • 14
    • 51349103144 scopus 로고    scopus 로고
    • Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer
    • Foekens JA, Sieuwerts AM, Smid M, et al. Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer. Proc Natl Acad Sci USA 2008; 105: 13021-13026.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 13021-13026
    • Foekens, J.A.1    Sieuwerts, A.M.2    Smid, M.3
  • 15
    • 77950862656 scopus 로고    scopus 로고
    • Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET
    • Matsui T, Leung D, Miyashita H, et al. Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET. Nature 2010; 464: 927-931.
    • (2010) Nature , vol.464 , pp. 927-931
    • Matsui, T.1    Leung, D.2    Miyashita, H.3
  • 16
    • 80055002815 scopus 로고    scopus 로고
    • Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3
    • Macgregor S, Montgomery GW, Liu JZ, et al. Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3. Nat Genet 2011; 43: 1114-1118.
    • (2011) Nat Genet , vol.43 , pp. 1114-1118
    • MacGregor, S.1    Montgomery, G.W.2    Liu, J.Z.3
  • 17
    • 79953056443 scopus 로고    scopus 로고
    • The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset
    • Ceol CJ, Houvras Y, Jane-Valbuena J, et al. The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset. Nature 2011; 471: 513-517.
    • (2011) Nature , vol.471 , pp. 513-517
    • Ceol, C.J.1    Houvras, Y.2    Jane-Valbuena, J.3
  • 18
    • 84901499830 scopus 로고    scopus 로고
    • Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis
    • Rodriguez-Paredes M, Martinez, de Paz A, Simo-Riudalbas L, et al. Gene amplification of the histone methyltransferase SETDB1 contributes to human lung tumorigenesis. Oncogene 2013.
    • (2013) Oncogene
    • Rodriguez-Paredes, M.1    Martinez2    De Paz, A.3    Simo-Riudalbas, L.4
  • 19
    • 39849100039 scopus 로고    scopus 로고
    • Isolation and identification of cancer stem-like cells from murine melanoma cell lines
    • Dou J, Pan M, Wen P, et al. Isolation and identification of cancer stem-like cells from murine melanoma cell lines. Cell Mol Immunol 2007; 4: 467-472.
    • (2007) Cell Mol Immunol , vol.4 , pp. 467-472
    • Dou, J.1    Pan, M.2    Wen, P.3
  • 20
    • 84860512772 scopus 로고    scopus 로고
    • Selective removal of undifferentiated human embryonic stem cells using magnetic activated cell sorting followed by a cytotoxic antibody
    • Schriebl K, Satianegara G, Hwang A, et al. Selective removal of undifferentiated human embryonic stem cells using magnetic activated cell sorting followed by a cytotoxic antibody. Tissue Eng 2012; 18: 899-909.
    • (2012) Tissue Eng , vol.18 , pp. 899-909
    • Schriebl, K.1    Satianegara, G.2    Hwang, A.3
  • 21
    • 84864675063 scopus 로고    scopus 로고
    • Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells
    • Zhang H, Wang J, Cai K, et al. Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. J Cancer Res Therap 2012; 8: 226-231.
    • (2012) J Cancer Res Therap , vol.8 , pp. 226-231
    • Zhang, H.1    Wang, J.2    Cai, K.3
  • 22
    • 0034618521 scopus 로고    scopus 로고
    • Structure and functional analysis of the human STAT3 gene promoter: Alteration of chromatin structure as a possible mechanism for the upregulation in cisplatin-resistant cells
    • Kato K, Nomoto M, Izumi H, et al. Structure and functional analysis of the human STAT3 gene promoter: Alteration of chromatin structure as a possible mechanism for the upregulation in cisplatin-resistant cells. Biochim Biophys 2000; 1493: 91-100.
    • (2000) Biochim Biophys , vol.1493 , pp. 91-100
    • Kato, K.1    Nomoto, M.2    Izumi, H.3
  • 23
    • 79960918651 scopus 로고    scopus 로고
    • Transwell((R)) invasion assays
    • Marshall J,. Transwell((R)) invasion assays. Meth Mol Biol 2011; 769: 97-110.
    • (2011) Meth Mol Biol , vol.769 , pp. 97-110
    • Marshall, J.1
  • 24
    • 79751484450 scopus 로고    scopus 로고
    • Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma
    • Hou J, Lin L, Zhou W, et al. Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 2011; 19: 232-243.
    • (2011) Cancer Cell , vol.19 , pp. 232-243
    • Hou, J.1    Lin, L.2    Zhou, W.3
  • 25
    • 38449121657 scopus 로고    scopus 로고
    • Development of an optimal antigen retrieval protocol for immunohistochemistry of retinoblastoma protein (pRB) in formalin fixed, paraffin sections based on comparison of different methods
    • Shi SR, Liu C, Young L, et al. Development of an optimal antigen retrieval protocol for immunohistochemistry of retinoblastoma protein (pRB) in formalin fixed, paraffin sections based on comparison of different methods. Biotech Histochem 2007; 82: 301-309.
    • (2007) Biotech Histochem , vol.82 , pp. 301-309
    • Shi, S.R.1    Liu, C.2    Young, L.3
  • 26
    • 68749097208 scopus 로고    scopus 로고
    • MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer
    • Ng EK, Tsang WP, Ng SS, et al. MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. Br J Cancer 2009; 101: 699-706.
    • (2009) Br J Cancer , vol.101 , pp. 699-706
    • Ng, E.K.1    Tsang, W.P.2    Ng, S.S.3
  • 27
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek A, Grun D, Poy MN, et al. Combinatorial microRNA target predictions. Nat Genet 2005; 37: 495-500.
    • (2005) Nat Genet , vol.37 , pp. 495-500
    • Krek, A.1    Grun, D.2    Poy, M.N.3
  • 28
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP,. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 29
    • 84899910676 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent
    • Davis FM, Azimi I, Faville RA, et al. Induction of epithelial-mesenchymal transition (EMT) in breast cancer cells is calcium signal dependent. Oncogene 2014; 33: 2307-2316.
    • (2014) Oncogene , vol.33 , pp. 2307-2316
    • Davis, F.M.1    Azimi, I.2    Faville, R.A.3
  • 31
    • 79959956046 scopus 로고    scopus 로고
    • The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors
    • Marotta LL, Almendro V, Marusyk A, et al. The JAK2/STAT3 signaling pathway is required for growth of CD44(+)CD24(-) stem cell-like breast cancer cells in human tumors. J Clin Invest 2011; 121: 2723-2735.
    • (2011) J Clin Invest , vol.121 , pp. 2723-2735
    • Marotta, L.L.1    Almendro, V.2    Marusyk, A.3
  • 32
    • 35649026743 scopus 로고    scopus 로고
    • Anomalous behaviour of the STAT3 binding site in the human c-myc P2 promoter
    • Vougier S, Cheung SH, Li L, et al. Anomalous behaviour of the STAT3 binding site in the human c-myc P2 promoter. BBRC 2007; 364: 627-632.
    • (2007) BBRC , vol.364 , pp. 627-632
    • Vougier, S.1    Cheung, S.H.2    Li, L.3
  • 33
    • 77649275464 scopus 로고    scopus 로고
    • MiR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis
    • Ma L, Young J, Prabhala H, et al. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nature Cell Biol 2010; 12: 247-256.
    • (2010) Nature Cell Biol , vol.12 , pp. 247-256
    • Ma, L.1    Young, J.2    Prabhala, H.3
  • 34
    • 77951118936 scopus 로고    scopus 로고
    • Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
    • Gupta RA, Shah N, Wang KC, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature 2010; 464: 1071-1076.
    • (2010) Nature , vol.464 , pp. 1071-1076
    • Gupta, R.A.1    Shah, N.2    Wang, K.C.3
  • 35
    • 54249093368 scopus 로고    scopus 로고
    • MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions
    • Reddy SD, Ohshiro K, Rayala SK, et al. MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions. Cancer Res 2008; 68: 8195-8200.
    • (2008) Cancer Res , vol.68 , pp. 8195-8200
    • Reddy, S.D.1    Ohshiro, K.2    Rayala, S.K.3
  • 36
    • 84876489727 scopus 로고    scopus 로고
    • Cancer stem cells: The challenges ahead
    • Medema JP,. Cancer stem cells: the challenges ahead. Nature Cell Biol 2013; 15: 338-344.
    • (2013) Nature Cell Biol , vol.15 , pp. 338-344
    • Medema, J.P.1
  • 38
    • 0141992115 scopus 로고    scopus 로고
    • MAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression
    • Wang H, An W, Cao R, et al. mAM facilitates conversion by ESET of dimethyl to trimethyl lysine 9 of histone H3 to cause transcriptional repression. Mol Cell 2003; 12: 475-487.
    • (2003) Mol Cell , vol.12 , pp. 475-487
    • Wang, H.1    An, W.2    Cao, R.3
  • 39
    • 84862806829 scopus 로고    scopus 로고
    • IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis
    • Rokavec M, Wu W, Luo JL,. IL6-mediated suppression of miR-200c directs constitutive activation of inflammatory signaling circuit driving transformation and tumorigenesis. Mol Cell 2012; 45: 777-789.
    • (2012) Mol Cell , vol.45 , pp. 777-789
    • Rokavec, M.1    Wu, W.2    Luo, J.L.3
  • 40
    • 84878973699 scopus 로고    scopus 로고
    • Cancer Stem Cells Activate STAT3 the EZ Way
    • Fouse SD, Costello JF,. Cancer Stem Cells Activate STAT3 the EZ Way. Cancer Cell 2013; 23: 711-713.
    • (2013) Cancer Cell , vol.23 , pp. 711-713
    • Fouse, S.D.1    Costello, J.F.2
  • 41
    • 84879000598 scopus 로고    scopus 로고
    • Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells
    • Kim E, Kim M, Woo DH, et al. Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells. Cancer Cell 2013; 23: 839-852.
    • (2013) Cancer Cell , vol.23 , pp. 839-852
    • Kim, E.1    Kim, M.2    Woo, D.H.3
  • 43
    • 47249161129 scopus 로고    scopus 로고
    • Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function
    • Cheng GZ, Zhang WZ, Sun M, et al. Twist is transcriptionally induced by activation of STAT3 and mediates STAT3 oncogenic function. JBC 2008; 283: 14665-14673.
    • (2008) JBC , vol.283 , pp. 14665-14673
    • Cheng, G.Z.1    Zhang, W.Z.2    Sun, M.3
  • 44
    • 84864422842 scopus 로고    scopus 로고
    • MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression
    • Kong X, Li G, Yuan Y, et al. MicroRNA-7 inhibits epithelial-to-mesenchymal transition and metastasis of breast cancer cells via targeting FAK expression. PloS ONE 2012; 7: e41523.
    • (2012) PloS ONE , vol.7 , pp. e41523
    • Kong, X.1    Li, G.2    Yuan, Y.3
  • 45
    • 30644467070 scopus 로고    scopus 로고
    • RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth
    • Zhang W, Zong CS, Hermanto U, et al. RACK1 recruits STAT3 specifically to insulin and insulin-like growth factor 1 receptors for activation, which is important for regulating anchorage-independent growth. MCB 2006; 26: 413-424.
    • (2006) MCB , vol.26 , pp. 413-424
    • Zhang, W.1    Zong, C.S.2    Hermanto, U.3
  • 46
    • 78649728328 scopus 로고    scopus 로고
    • MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells
    • Jiang L, Liu X, Chen Z, et al. MicroRNA-7 targets IGF1R (insulin-like growth factor 1 receptor) in tongue squamous cell carcinoma cells. Biochem J 2010; 432: 199-205.
    • (2010) Biochem J , vol.432 , pp. 199-205
    • Jiang, L.1    Liu, X.2    Chen, Z.3
  • 47
    • 84876367541 scopus 로고    scopus 로고
    • Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal
    • Wang Y, Xu Z, Jiang J, et al. Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal. Dev Cell 2013; 25: 69-80.
    • (2013) Dev Cell , vol.25 , pp. 69-80
    • Wang, Y.1    Xu, Z.2    Jiang, J.3


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