-
1
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004; 116:281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
2
-
-
24644446398
-
Ribo-gnome: the big world of small RNAs
-
Zamore PD, Haley B. Ribo-gnome: the big world of small RNAs. Science. 2005; 309:1519-1524.
-
(2005)
Science
, vol.309
, pp. 1519-1524
-
-
Zamore, P.D.1
Haley, B.2
-
3
-
-
36749026906
-
Switching from repression to activation: microRNAs can up-regulate translation
-
Vasudevan S, Tong Y, Steitz JA. Switching from repression to activation: microRNAs can up-regulate translation. Science. 2007; 318:1931-1934.
-
(2007)
Science
, vol.318
, pp. 1931-1934
-
-
Vasudevan, S.1
Tong, Y.2
Steitz, J.A.3
-
4
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
He L, Hannon GJ. MicroRNAs: small RNAs with a big role in gene regulation. Nat Rev Genet. 2004; 5:522-531.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
5
-
-
70349320158
-
Causes and consequences of microRNA dysregulation in cancer
-
Croce CM. Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet. 2009; 10:704-714.
-
(2009)
Nat Rev Genet
, vol.10
, pp. 704-714
-
-
Croce, C.M.1
-
6
-
-
39049086391
-
MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN
-
Yang H, Kong W, He L, Zhao JJ, O'Donnell JD, Wang J, Wenham RM, Coppola D, Kruk PA, Nicosia SV, Cheng JQ. MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res. 2008; 68:425-433.
-
(2008)
Cancer Res
, vol.68
, pp. 425-433
-
-
Yang, H.1
Kong, W.2
He, L.3
Zhao, J.J.4
O'Donnell, J.D.5
Wang, J.6
Wenham, R.M.7
Coppola, D.8
Kruk, P.A.9
Nicosia, S.V.10
Cheng, J.Q.11
-
7
-
-
65249186793
-
The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors
-
Northcott PA, Fernandez LA, Hagan JP, Ellison DW, Grajkowska W, Gillespie Y, Grundy R, Van Meter T, Rutka JT, Croce CM, Kenney AM, Taylor MD. The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors. Cancer Res. 2009; 69:3249-3255.
-
(2009)
Cancer Res
, vol.69
, pp. 3249-3255
-
-
Northcott, P.A.1
Fernandez, L.A.2
Hagan, J.P.3
Ellison, D.W.4
Grajkowska, W.5
Gillespie, Y.6
Grundy, R.7
Van Meter, T.8
Rutka, J.T.9
Croce, C.M.10
Kenney, A.M.11
Taylor, M.D.12
-
8
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A, Labourier E, Reinert KL, Brown D, Slack FJ. RAS is regulated by the let-7 microRNA family. Cell. 2005; 120:635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
Labourier, E.7
Reinert, K.L.8
Brown, D.9
Slack, F.J.10
-
9
-
-
65549115615
-
miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon
-
Gandellini P, Folini M, Longoni N, Pennati M, Binda M, Colecchia M, Salvioni R, Supino R, Moretti R, Limonta P, Valdagni R, Daidone MG, Zaffaroni N. miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon. Cancer Res. 2009; 69:2287-2295.
-
(2009)
Cancer Res
, vol.69
, pp. 2287-2295
-
-
Gandellini, P.1
Folini, M.2
Longoni, N.3
Pennati, M.4
Binda, M.5
Colecchia, M.6
Salvioni, R.7
Supino, R.8
Moretti, R.9
Limonta, P.10
Valdagni, R.11
Daidone, M.G.12
Zaffaroni, N.13
-
10
-
-
18344389720
-
Causal relationship between the loss of RUNX3 expression and gastric cancer
-
Li QL, Ito K, Sakakura C, Fukamachi H, Inoue K, Chi XZ, Lee KY, Nomura S, Lee CW, Han SB, Kim HM, Kim WJ, Yamamoto H, et al. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell. 2002; 109:113-124.
-
(2002)
Cell
, vol.109
, pp. 113-124
-
-
Li, Q.L.1
Ito, K.2
Sakakura, C.3
Fukamachi, H.4
Inoue, K.5
Chi, X.Z.6
Lee, K.Y.7
Nomura, S.8
Lee, C.W.9
Han, S.B.10
Kim, H.M.11
Kim, W.J.12
Yamamoto, H.13
-
11
-
-
0037216494
-
TGF beta/Smad signaling system and its pathologic correlates
-
Cohen MM Jr. TGF beta/Smad signaling system and its pathologic correlates. Am J Med Genet A. 2003; 116A:1-10.
-
(2003)
Am J Med Genet A
, vol.116A
, pp. 1-10
-
-
Cohen, M.M.1
-
12
-
-
24344500170
-
RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD
-
Chi XZ, Yang JO, Lee KY, Ito K, Sakakura C, Li QL, Kim HR, Cha EJ, Lee YH, Kaneda A, Ushijima T, Kim WJ, Ito Y, et al. RUNX3 suppresses gastric epithelial cell growth by inducing p21(WAF1/Cip1) expression in cooperation with transforming growth factor {beta}-activated SMAD. Mol Cell Biol. 2005; 25:8097-8107.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 8097-8107
-
-
Chi, X.Z.1
Yang, J.O.2
Lee, K.Y.3
Ito, K.4
Sakakura, C.5
Li, Q.L.6
Kim, H.R.7
Cha, E.J.8
Lee, Y.H.9
Kaneda, A.10
Ushijima, T.11
Kim, W.J.12
Ito, Y.13
-
13
-
-
33745018595
-
The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis
-
Yano T, Ito K, Fukamachi H, Chi XZ, Wee HJ, Inoue K, Ida H, Bouillet P, Strasser A, Bae SC, Ito Y. The RUNX3 tumor suppressor upregulates Bim in gastric epithelial cells undergoing transforming growth factor beta-induced apoptosis. Mol Cell Biol. 2006; 26:4474-4488.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 4474-4488
-
-
Yano, T.1
Ito, K.2
Fukamachi, H.3
Chi, X.Z.4
Wee, H.J.5
Inoue, K.6
Ida, H.7
Bouillet, P.8
Strasser, A.9
Bae, S.C.10
Ito, Y.11
-
14
-
-
84887533067
-
Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma
-
Lee YS, Lee JW, Jang JW, Chi XZ, Kim JH, Li YH, Kim MK, Kim DM, Choi BS, Kim EG, Chung JH, Lee OJ, Lee YM, et al. Runx3 inactivation is a crucial early event in the development of lung adenocarcinoma. Cancer Cell. 2013; 24:603-616.
-
(2013)
Cancer Cell
, vol.24
, pp. 603-616
-
-
Lee, Y.S.1
Lee, J.W.2
Jang, J.W.3
Chi, X.Z.4
Kim, J.H.5
Li, Y.H.6
Kim, M.K.7
Kim, D.M.8
Choi, B.S.9
Kim, E.G.10
Chung, J.H.11
Lee, O.J.12
Lee, Y.M.13
-
15
-
-
25444454359
-
Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors
-
Sitkovsky M, Lukashev D. Regulation of immune cells by local-tissue oxygen tension: HIF1 alpha and adenosine receptors. Nat Rev Immunol. 2005; 5:712-721.
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 712-721
-
-
Sitkovsky, M.1
Lukashev, D.2
-
16
-
-
58249123443
-
Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells
-
Lee SH, Kim J, Kim WH, Lee YM. Hypoxic silencing of tumor suppressor RUNX3 by histone modification in gastric cancer cells. Oncogene. 2009; 28:184-194.
-
(2009)
Oncogene
, vol.28
, pp. 184-194
-
-
Lee, S.H.1
Kim, J.2
Kim, W.H.3
Lee, Y.M.4
-
17
-
-
84896388770
-
RUNX3 inhibits hypoxia-inducible factor-1alpha protein stability by interacting with prolyl hydroxylases in gastric cancer cells
-
Lee SH, Bae SC, Kim KW, Lee YM. RUNX3 inhibits hypoxia-inducible factor-1alpha protein stability by interacting with prolyl hydroxylases in gastric cancer cells. Oncogene. 2014; 33:1458-1467.
-
(2014)
Oncogene
, vol.33
, pp. 1458-1467
-
-
Lee, S.H.1
Bae, S.C.2
Kim, K.W.3
Lee, Y.M.4
-
18
-
-
24744470103
-
RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization
-
Ito K, Liu Q, Salto-Tellez M, Yano T, Tada K, Ida H, Huang C, Shah N, Inoue M, Rajnakova A, Hiong KC, Peh BK, Han HC, et al. RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization. Cancer Res. 2005; 65:7743-7750.
-
(2005)
Cancer Res
, vol.65
, pp. 7743-7750
-
-
Ito, K.1
Liu, Q.2
Salto-Tellez, M.3
Yano, T.4
Tada, K.5
Ida, H.6
Huang, C.7
Shah, N.8
Inoue, M.9
Rajnakova, A.10
Hiong, K.C.11
Peh, B.K.12
Han, H.C.13
-
19
-
-
47749134140
-
Enhancer of zeste homologue 2 down-regulates RUNX3 by increasing histone H3 methylation
-
Fujii S, Ito K, Ito Y, Ochiai A. Enhancer of zeste homologue 2 down-regulates RUNX3 by increasing histone H3 methylation. J Biol Chem. 2008; 283:17324-17332.
-
(2008)
J Biol Chem
, vol.283
, pp. 17324-17332
-
-
Fujii, S.1
Ito, K.2
Ito, Y.3
Ochiai, A.4
-
20
-
-
1142299739
-
Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma
-
Xiao WH, Liu WW. Hemizygous deletion and hypermethylation of RUNX3 gene in hepatocellular carcinoma. World J Gastroenterol. 2004; 10:376-380.
-
(2004)
World J Gastroenterol
, vol.10
, pp. 376-380
-
-
Xiao, W.H.1
Liu, W.W.2
-
21
-
-
4644309196
-
The functions of animal microRNAs
-
Ambros V. The functions of animal microRNAs. Nature. 2004; 431:350-355.
-
(2004)
Nature
, vol.431
, pp. 350-355
-
-
Ambros, V.1
-
22
-
-
20444436381
-
Cancer genomics: small RNAs with big impacts
-
Meltzer PS. Cancer genomics: small RNAs with big impacts. Nature. 2005; 435:745-746.
-
(2005)
Nature
, vol.435
, pp. 745-746
-
-
Meltzer, P.S.1
-
23
-
-
33750370444
-
MicroRNA signatures in human cancers
-
Calin GA, Croce CM. MicroRNA signatures in human cancers. Nat Rev Cancer. 2006; 6:857-866.
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 857-866
-
-
Calin, G.A.1
Croce, C.M.2
-
24
-
-
84896388770
-
RUNX3 inhibits hypoxia-inducible factor-1 alpha protein stability by interacting with prolyl hydroxylases in gastric cancer cells
-
Lee SH, Bae SC, Kim KW, Lee YM. RUNX3 inhibits hypoxia-inducible factor-1 alpha protein stability by interacting with prolyl hydroxylases in gastric cancer cells. Oncogene. 2014; 33:1458-1467.
-
(2014)
Oncogene
, vol.33
, pp. 1458-1467
-
-
Lee, S.H.1
Bae, S.C.2
Kim, K.W.3
Lee, Y.M.4
-
25
-
-
84859404834
-
miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells
-
Kovaleva V, Mora R, Park YJ, Plass C, Chiramel AI, Bartenschlager R, Dohner H, Stilgenbauer S, Pscherer A, Lichter P, Seiffert M. miRNA-130a targets ATG2B and DICER1 to inhibit autophagy and trigger killing of chronic lymphocytic leukemia cells. Cancer Res. 2012; 72:1763-1772.
-
(2012)
Cancer Res
, vol.72
, pp. 1763-1772
-
-
Kovaleva, V.1
Mora, R.2
Park, Y.J.3
Plass, C.4
Chiramel, A.I.5
Bartenschlager, R.6
Dohner, H.7
Stilgenbauer, S.8
Pscherer, A.9
Lichter, P.10
Seiffert, M.11
-
26
-
-
79957613439
-
miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1
-
Hwang-Verslues WW, Chang PH, Wei PC, Yang CY, Huang CK, Kuo WH, Shew JY, Chang KJ, Lee EY, Lee WH. miR-495 is upregulated by E12/E47 in breast cancer stem cells, and promotes oncogenesis and hypoxia resistance via downregulation of E-cadherin and REDD1. Oncogene. 2011; 30:2463-2474.
-
(2011)
Oncogene
, vol.30
, pp. 2463-2474
-
-
Hwang-Verslues, W.W.1
Chang, P.H.2
Wei, P.C.3
Yang, C.Y.4
Huang, C.K.5
Kuo, W.H.6
Shew, J.Y.7
Chang, K.J.8
Lee, E.Y.9
Lee, W.H.10
-
27
-
-
84865348811
-
Upregulated miR-130a increases drug resistance by regulating RUNX3 and Wnt signaling in cisplatin-treated HCC cell
-
Xu N, Shen C, Luo Y, Xia L, Xue F, Xia Q, Zhang J. Upregulated miR-130a increases drug resistance by regulating RUNX3 and Wnt signaling in cisplatin-treated HCC cell. Biochem Biophys Res Commun. 2012; 425:468-472.
-
(2012)
Biochem Biophys Res Commun
, vol.425
, pp. 468-472
-
-
Xu, N.1
Shen, C.2
Luo, Y.3
Xia, L.4
Xue, F.5
Xia, Q.6
Zhang, J.7
-
28
-
-
84880074565
-
Downregulation of microRNA-130a contributes to endothelial progenitor cell dysfunction in diabetic patients via its target Runx3
-
Meng S, Cao J, Zhang X, Fan Y, Fang L, Wang C, Lv Z, Fu D, Li Y. Downregulation of microRNA-130a contributes to endothelial progenitor cell dysfunction in diabetic patients via its target Runx3. PLoS One. 2013; 8:e68611.
-
(2013)
PLoS One
, vol.8
-
-
Meng, S.1
Cao, J.2
Zhang, X.3
Fan, Y.4
Fang, L.5
Wang, C.6
Lv, Z.7
Fu, D.8
Li, Y.9
-
29
-
-
84883488449
-
MicroRNA-106a induces multidrug resistance in gastric cancer by targeting RUNX3
-
Zhang Y, Lu Q, Cai X. MicroRNA-106a induces multidrug resistance in gastric cancer by targeting RUNX3. FEBS Lett. 2013; 587:3069-3075.
-
(2013)
FEBS Lett
, vol.587
, pp. 3069-3075
-
-
Zhang, Y.1
Lu, Q.2
Cai, X.3
-
30
-
-
84884227396
-
MicroRNA-106b regulates the tumor suppressor RUNX3 in laryngeal carcinoma cells
-
Xu Y, Wang K, Gao W, Zhang C, Huang F, Wen S, Wang B. MicroRNA-106b regulates the tumor suppressor RUNX3 in laryngeal carcinoma cells. FEBS Lett. 2013; 587:3166-3174.
-
(2013)
FEBS Lett
, vol.587
, pp. 3166-3174
-
-
Xu, Y.1
Wang, K.2
Gao, W.3
Zhang, C.4
Huang, F.5
Wen, S.6
Wang, B.7
-
31
-
-
65649092616
-
Regulation of RUNX3 tumor suppressor gene expression in cutaneous melanoma
-
Kitago M, Martinez SR, Nakamura T, Sim MS, Hoon DS. Regulation of RUNX3 tumor suppressor gene expression in cutaneous melanoma. Clin Cancer Res. 2009; 15:2988-2994.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2988-2994
-
-
Kitago, M.1
Martinez, S.R.2
Nakamura, T.3
Sim, M.S.4
Hoon, D.S.5
|