-
1
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp, R., Mason, W.P., van den Bent, M.J., Weller, M., Fisher, B., Taphoorn, M.J., Belanger, K., Brandes, A.A., Marosi, C., Bogdahn, U. et al. (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N. Engl. J. Med., 352, 987-996.
-
(2005)
N. Engl. J. Med.
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
van den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
-
2
-
-
76749157903
-
Advances in the treatment of malignant gliomas
-
Khasraw, M. and Lassman, A.B. (2010) Advances in the treatment of malignant gliomas. Curr. Oncol. Rep., 12, 26-33.
-
(2010)
Curr. Oncol. Rep.
, vol.12
, pp. 26-33
-
-
Khasraw, M.1
Lassman, A.B.2
-
3
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
-
Stupp, R., Hegi, M.E., Mason, W.P., van den Bent, M.J., Taphoorn, M.J., Janzer, R.C., Ludwin, S.K., Allgeier, A., Fisher, B., Belanger, K. et al. (2009) Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol., 10, 459-466.
-
(2009)
Lancet Oncol
, vol.10
, pp. 459-466
-
-
Stupp, R.1
Hegi, M.E.2
Mason, W.P.3
van den Bent, M.J.4
Taphoorn, M.J.5
Janzer, R.C.6
Ludwin, S.K.7
Allgeier, A.8
Fisher, B.9
Belanger, K.10
-
4
-
-
1942435249
-
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs
-
Bartel, D.P. and Chen, C.Z. (2004) Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet., 5, 396-400.
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 396-400
-
-
Bartel, D.P.1
Chen, C.Z.2
-
5
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo, H., Ingolia, N.T., Weissman, J.S. and Bartel, D.P. (2010) Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature, 466, 835-840.
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
6
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel, D.P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
7
-
-
33645294070
-
Oncomirs-microRNAs with a role in cancer
-
Esquela-Kerscher, A. and Slack, F.J. (2006) Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer, 6, 259-269.
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
8
-
-
27244434788
-
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
-
Calin, G.A., Ferracin, M., Cimmino, A., Di Leva, G., Shimizu, M., Wojcik, S.E., Iorio, M.V., Visone, R., Sever, N.I., Fabbri, M. et al. (2005) A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N. Engl. J. Med., 353, 1793-1801.
-
(2005)
N. Engl. J. Med.
, vol.353
, pp. 1793-1801
-
-
Calin, G.A.1
Ferracin, M.2
Cimmino, A.3
Di Leva, G.4
Shimizu, M.5
Wojcik, S.E.6
Iorio, M.V.7
Visone, R.8
Sever, N.I.9
Fabbri, M.10
-
9
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia, S., Calin, G.A., Liu, C.G., Ambs, S., Cimmino, A., Petrocca, F., Visone, R., Iorio, M., Roldo, C., Ferracin, M. et al. (2006) A microRNA expression signature of human solid tumors defines cancer gene targets. Proc. Natl. Acad. Sci. USA, 103, 2257-2261.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
Ambs, S.4
Cimmino, A.5
Petrocca, F.6
Visone, R.7
Iorio, M.8
Roldo, C.9
Ferracin, M.10
-
10
-
-
23044464236
-
Extensive modulation of a set of microRNAs in primary glioblastoma
-
Ciafre, S.A., Galardi, S., Mangiola, A., Ferracin, M., Liu, C.G., Sabatino, G., Negrini, M., Maira, G., Croce, C.M. and Farace, M.G. (2005) Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem. Biophys. Res. Commun., 334, 1351-1358.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.334
, pp. 1351-1358
-
-
Ciafre, S.A.1
Galardi, S.2
Mangiola, A.3
Ferracin, M.4
Liu, C.G.5
Sabatino, G.6
Negrini, M.7
Maira, G.8
Croce, C.M.9
Farace, M.G.10
-
11
-
-
30644479193
-
Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1 3-bis(2-chloroethyl)-1-nitrosourea
-
Hank, N.C., Shapiro, J.R. and Scheck, A.C. (2006) Over-representation of specific regions of chromosome 22 in cells from human glioma correlate with resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea. BMC Cancer, 6, 2.
-
(2006)
BMC Cancer
, vol.6
, pp. 2
-
-
Hank, N.C.1
Shapiro, J.R.2
Scheck, A.C.3
-
12
-
-
73649123907
-
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1
-
Verhaak, R.G., Hoadley, K.A., Purdom, E., Wang, V., Qi, Y., Wilkerson, M.D., Miller, C.R., Ding, L., Golub, T., Mesirov, J.P. et al. (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell, 17, 98-110.
-
(2010)
Cancer Cell
, vol.17
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
Miller, C.R.7
Ding, L.8
Golub, T.9
Mesirov, J.P.10
-
13
-
-
34250877865
-
Genetic pathways to primary and secondary glioblastoma
-
Ohgaki, H. and Kleihues, P. (2007) Genetic pathways to primary and secondary glioblastoma. Am. J. Pathol., 170, 1445-1453.
-
(2007)
Am. J. Pathol.
, vol.170
, pp. 1445-1453
-
-
Ohgaki, H.1
Kleihues, P.2
-
14
-
-
63649110495
-
Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells
-
Lena, A., Rechichi, M., Salvetti, A., Bartoli, B., Vecchio, D., Scarcelli, V., Amoroso, R., Benvenuti, L., Gagliardi, R., Gremigni, V. et al. (2009) Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells. J. Transl. Med., 7, 13.
-
(2009)
J. Transl. Med.
, vol.7
, pp. 13
-
-
Lena, A.1
Rechichi, M.2
Salvetti, A.3
Bartoli, B.4
Vecchio, D.5
Scarcelli, V.6
Amoroso, R.7
Benvenuti, L.8
Gagliardi, R.9
Gremigni, V.10
-
15
-
-
31544474851
-
Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma
-
Prados, M.D., Lamborn, K.R., Chang, S., Burton, E., Butowski, N., Malec, M., Kapadia, A., Rabbitt, J., Page, M.S., Fedoroff, A. et al. (2006) Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma. Neuro. Oncol., 8, 67-78.
-
(2006)
Neuro. Oncol.
, vol.8
, pp. 67-78
-
-
Prados, M.D.1
Lamborn, K.R.2
Chang, S.3
Burton, E.4
Butowski, N.5
Malec, M.6
Kapadia, A.7
Rabbitt, J.8
Page, M.S.9
Fedoroff, A.10
-
16
-
-
65249121446
-
Emerging functions of microRNAs in glioblastoma
-
Lawler, S. and Chiocca, E.A. (2009) Emerging functions of microRNAs in glioblastoma. J. Neurooncol., 92, 297-306.
-
(2009)
J. Neurooncol.
, vol.92
, pp. 297-306
-
-
Lawler, S.1
Chiocca, E.A.2
-
17
-
-
48949116262
-
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
-
Silber, J., Lim, D.A., Petritsch, C., Persson, A.I., Maunakea, A.K., Yu, M., Vandenberg, S.R., Ginzinger, D.G., James, C.D., Costello, J.F. et al. (2008) miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells. BMC Med., 6, 14.
-
(2008)
BMC Med
, vol.6
, pp. 14
-
-
Silber, J.1
Lim, D.A.2
Petritsch, C.3
Persson, A.I.4
Maunakea, A.K.5
Yu, M.6
Vandenberg, S.R.7
Ginzinger, D.G.8
James, C.D.9
Costello, J.F.10
-
18
-
-
56449126945
-
Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal
-
Godlewski, J., Nowicki, M.O., Bronisz, A., Williams, S., Otsuki, A., Nuovo, G., Raychaudhury, A., Newton, H.B., Chiocca, E.A. and Lawler, S. (2008) Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. Cancer Res., 68, 9125-9130.
-
(2008)
Cancer Res
, vol.68
, pp. 9125-9130
-
-
Godlewski, J.1
Nowicki, M.O.2
Bronisz, A.3
Williams, S.4
Otsuki, A.5
Nuovo, G.6
Raychaudhury, A.7
Newton, H.B.8
Chiocca, E.A.9
Lawler, S.10
-
19
-
-
78049285307
-
Novel targeted agents for platelet-derived growth factor receptor and c-KIT in malignant gliomas
-
Morris, P.G. and Abrey, L.E. (2010) Novel targeted agents for platelet-derived growth factor receptor and c-KIT in malignant gliomas. Target Oncol., 5, 193-200.
-
(2010)
Target Oncol
, vol.5
, pp. 193-200
-
-
Morris, P.G.1
Abrey, L.E.2
-
20
-
-
79956361405
-
Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype
-
Lei, L., Sonabend, A.M., Guarnieri, P., Soderquist, C., Ludwig, T., Rosenfeld, S., Bruce, J.N. and Canoll, P. (2011) Glioblastoma models reveal the connection between adult glial progenitors and the proneural phenotype. PLoS One, 6, e20041.
-
(2011)
PLoS One
, vol.6
-
-
Lei, L.1
Sonabend, A.M.2
Guarnieri, P.3
Soderquist, C.4
Ludwig, T.5
Rosenfeld, S.6
Bruce, J.N.7
Canoll, P.8
-
21
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
Chan, J.A., Krichevsky, A.M. and Kosik, K.S. (2005) MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res., 65, 6029-6033.
-
(2005)
Cancer Res
, vol.65
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
22
-
-
67349247040
-
miR-21 and 221 upregulation and miR-181b downregulation in human grade II-IV astrocytic tumors
-
Conti, A., Aguennouz, M., La Torre, D., Tomasello, C., Cardali, S., Angileri, F.F., Maio, F., Cama, A., Germano, A., Vita, G. et al. (2009) miR-21 and 221 upregulation and miR-181b downregulation in human grade II-IV astrocytic tumors. J. Neurooncol., 93, 325-332.
-
(2009)
J. Neurooncol.
, vol.93
, pp. 325-332
-
-
Conti, A.1
Aguennouz, M.2
La Torre, D.3
Tomasello, C.4
Cardali, S.5
Angileri, F.F.6
Maio, F.7
Cama, A.8
Germano, A.9
Vita, G.10
-
23
-
-
54549108740
-
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
-
Network, C.G.A.R. (2008) Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature, 455, 1061-1068.
-
(2008)
Nature
, vol.455
, pp. 1061-1068
-
-
Network, C.G.A.R.1
-
24
-
-
70349309149
-
miR-21 as a key regulator of oncogenic processes
-
Selcuklu, S.D., Donoghue, M.T. and Spillane, C. (2009) miR-21 as a key regulator of oncogenic processes. Biochem. Soc. Trans., 37, 918-925.
-
(2009)
Biochem. Soc. Trans.
, vol.37
, pp. 918-925
-
-
Selcuklu, S.D.1
Donoghue, M.T.2
Spillane, C.3
-
25
-
-
40249092910
-
MicroRNA-21 targets tumor suppressor genes in invasion and metastasis
-
Zhu, S., Wu, H., Wu, F., Nie, D., Sheng, S. and Mo, Y.Y. (2008) MicroRNA-21 targets tumor suppressor genes in invasion and metastasis. Cell Res., 18, 350-359.
-
(2008)
Cell Res
, vol.18
, pp. 350-359
-
-
Zhu, S.1
Wu, H.2
Wu, F.3
Nie, D.4
Sheng, S.5
Mo, Y.Y.6
-
26
-
-
77953961849
-
A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides
-
Trabulo, S., Resina, S., Simoes, S., Lebleu, B. and Pedroso de Lima, M.C. (2010) A non-covalent strategy combining cationic lipids and CPPs to enhance the delivery of splice correcting oligonucleotides. J. Control Release, 145, 149-158.
-
(2010)
J. Control Release
, vol.145
, pp. 149-158
-
-
Trabulo, S.1
Resina, S.2
Simoes, S.3
Lebleu, B.4
Pedroso de Lima, M.C.5
-
27
-
-
47549109566
-
MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene
-
Lu, Z., Liu, M., Stribinskis, V., Klinge, C.M., Ramos, K.S., Colburn, N.H. and Li, Y. (2008) MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene, 27, 4373-4379.
-
(2008)
Oncogene
, vol.27
, pp. 4373-4379
-
-
Lu, Z.1
Liu, M.2
Stribinskis, V.3
Klinge, C.M.4
Ramos, K.S.5
Colburn, N.H.6
Li, Y.7
-
28
-
-
34547524771
-
MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
-
Meng, F., Henson, R., Wehbe-Janek, H., Ghoshal, K., Jacob, S.T. and Patel, T. (2007) MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology, 133, 647-658.
-
(2007)
Gastroenterology
, vol.133
, pp. 647-658
-
-
Meng, F.1
Henson, R.2
Wehbe-Janek, H.3
Ghoshal, K.4
Jacob, S.T.5
Patel, T.6
-
29
-
-
54249136806
-
MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells
-
Papagiannakopoulos, T., Shapiro, A. and Kosik, K.S. (2008) MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells. Cancer Res., 68, 8164-8172.
-
(2008)
Cancer Res
, vol.68
, pp. 8164-8172
-
-
Papagiannakopoulos, T.1
Shapiro, A.2
Kosik, K.S.3
-
30
-
-
77957850069
-
p53 and NF-kappaB: different strategies for responding to stress lead to a functional antagonism
-
Ak, P. and Levine, A.J. (2010) p53 and NF-kappaB: different strategies for responding to stress lead to a functional antagonism. FASEB J, 24, 3643-3652.
-
(2010)
FASEB J
, vol.24
, pp. 3643-3652
-
-
Ak, P.1
Levine, A.J.2
-
31
-
-
33847230852
-
The p53 family in differentiation and tumorigenesis
-
Stiewe, T. (2007) The p53 family in differentiation and tumorigenesis. Nat. Rev. Cancer, 7, 165-168.
-
(2007)
Nat. Rev. Cancer
, vol.7
, pp. 165-168
-
-
Stiewe, T.1
-
32
-
-
78149339004
-
Pifithrin-alpha, an inhibitor of p53 transactivation, up-regulates COX-2 expression through an MAPK-dependent pathway
-
Kim, S., Han, J., Lee, S.K., Hur, S.M., Koo, M., Cho, D.H., Bae, S.Y., Choi, M.Y., Shin, I., Yang, J.H. et al. (2010) Pifithrin-alpha, an inhibitor of p53 transactivation, up-regulates COX-2 expression through an MAPK-dependent pathway. Pharmacology, 86, 313-319.
-
(2010)
Pharmacology
, vol.86
, pp. 313-319
-
-
Kim, S.1
Han, J.2
Lee, S.K.3
Hur, S.M.4
Koo, M.5
Cho, D.H.6
Bae, S.Y.7
Choi, M.Y.8
Shin, I.9
Yang, J.H.10
-
33
-
-
3142729912
-
Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation
-
Murphy, P.J., Galigniana, M.D., Morishima, Y., Harrell, J.M., Kwok, R.P., Ljungman, M. and Pratt, W.B. (2004) Pifithrin-alpha inhibits p53 signaling after interaction of the tumor suppressor protein with hsp90 and its nuclear translocation. J. Biol. Chem., 279, 30195-30201.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 30195-30201
-
-
Murphy, P.J.1
Galigniana, M.D.2
Morishima, Y.3
Harrell, J.M.4
Kwok, R.P.5
Ljungman, M.6
Pratt, W.B.7
-
34
-
-
84863142691
-
P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK
-
Fan, S., Qi, M., Yu, Y., Li, L., Yao, G., Tashiro, S., Onodera, S. and Ikejima, T. (2012) P53 activation plays a crucial role in silibinin induced ROS generation via PUMA and JNK. Free Radic. Res., 46, 310-319.
-
(2012)
Free Radic. Res.
, vol.46
, pp. 310-319
-
-
Fan, S.1
Qi, M.2
Yu, Y.3
Li, L.4
Yao, G.5
Tashiro, S.6
Onodera, S.7
Ikejima, T.8
-
35
-
-
31344468908
-
Effects of p53 inhibitor on survival and death of cells subjected to oxidative stress
-
Strosznajder, R.P., Jesko, H., Banasik, M. and Tanaka, S. (2005) Effects of p53 inhibitor on survival and death of cells subjected to oxidative stress. J. Physiol. Pharmacol., 56(Suppl. 4), 215-221.
-
(2005)
J. Physiol. Pharmacol.
, vol.56
, Issue.SUPPL. 4
, pp. 215-221
-
-
Strosznajder, R.P.1
Jesko, H.2
Banasik, M.3
Tanaka, S.4
-
36
-
-
2142673078
-
The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro
-
Rocha, S., Campbell, K.J., Roche, K.C. and Perkins, N.D. (2003) The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitro. BMC Mol. Biol., 4, 9.
-
(2003)
BMC Mol. Biol.
, vol.4
, pp. 9
-
-
Rocha, S.1
Campbell, K.J.2
Roche, K.C.3
Perkins, N.D.4
-
37
-
-
34247255527
-
p53 and NF-kappaB crosstalk: IKKalpha tips the balance
-
Tergaonkar, V. and Perkins, N.D. (2007) p53 and NF-kappaB crosstalk: IKKalpha tips the balance. Mol. Cell, 26, 158-159.
-
(2007)
Mol. Cell
, vol.26
, pp. 158-159
-
-
Tergaonkar, V.1
Perkins, N.D.2
-
38
-
-
80052014052
-
Inflammation meets cancer, with NF-kappaB as the matchmaker
-
Ben-Neriah, Y. and Karin, M. (2011) Inflammation meets cancer, with NF-kappaB as the matchmaker. Nat. Immunol., 12, 715-723.
-
(2011)
Nat. Immunol.
, vol.12
, pp. 715-723
-
-
Ben-Neriah, Y.1
Karin, M.2
-
39
-
-
50249173450
-
MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators
-
Gabriely, G., Wurdinger, T., Kesari, S., Esau, C.C., Burchard, J., Linsley, P.S. and Krichevsky, A.M. (2008) MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators. Mol. Cell Biol., 28, 5369-5380.
-
(2008)
Mol. Cell Biol.
, vol.28
, pp. 5369-5380
-
-
Gabriely, G.1
Wurdinger, T.2
Kesari, S.3
Esau, C.C.4
Burchard, J.5
Linsley, P.S.6
Krichevsky, A.M.7
-
40
-
-
79957498232
-
Specific miRNA signatures are associated with metastasis and poor prognosis in clear cell renal cell carcinoma
-
Heinzelmann, J., Henning, B., Sanjmyatav, J., Posorski, N., Steiner, T., Wunderlich, H., Gajda, M.R. and Junker, K. (2011) Specific miRNA signatures are associated with metastasis and poor prognosis in clear cell renal cell carcinoma. World J. Urol., 29, 367-373.
-
(2011)
World J. Urol.
, vol.29
, pp. 367-373
-
-
Heinzelmann, J.1
Henning, B.2
Sanjmyatav, J.3
Posorski, N.4
Steiner, T.5
Wunderlich, H.6
Gajda, M.R.7
Junker, K.8
-
41
-
-
77149174482
-
The microRNA network and tumor metastasis
-
Zhang, H., Li, Y. and Lai, M. (2010) The microRNA network and tumor metastasis. Oncogene, 29, 937-948.
-
(2010)
Oncogene
, vol.29
, pp. 937-948
-
-
Zhang, H.1
Li, Y.2
Lai, M.3
-
42
-
-
41749113108
-
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
-
Asangani, I.A., Rasheed, S.A., Nikolova, D.A., Leupold, J.H., Colburn, N.H., Post, S. and Allgayer, H. (2008) MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene, 27, 2128-2136.
-
(2008)
Oncogene
, vol.27
, pp. 2128-2136
-
-
Asangani, I.A.1
Rasheed, S.A.2
Nikolova, D.A.3
Leupold, J.H.4
Colburn, N.H.5
Post, S.6
Allgayer, H.7
-
43
-
-
34347266556
-
MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
-
Zhu, S., Si, M.L., Wu, H. and Mo, Y.Y. (2007) MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J. Biol. Chem., 282, 14328-14336.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14328-14336
-
-
Zhu, S.1
Si, M.L.2
Wu, H.3
Mo, Y.Y.4
-
44
-
-
79959977098
-
Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo
-
Gaur, A.B., Holbeck, S.L., Colburn, N.H. and Israel, M.A. (2011) Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo. Neuro. Oncol., 13, 580-590.
-
(2011)
Neuro. Oncol.
, vol.13
, pp. 580-590
-
-
Gaur, A.B.1
Holbeck, S.L.2
Colburn, N.H.3
Israel, M.A.4
-
45
-
-
79959794242
-
PI3Kinase signaling in glioblastoma
-
Lino, M.M. and Merlo, A. (2010) PI3Kinase signaling in glioblastoma. J. Neurooncol., 103, 417-427.
-
(2010)
J. Neurooncol.
, vol.103
, pp. 417-427
-
-
Lino, M.M.1
Merlo, A.2
-
46
-
-
75949106927
-
Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status
-
Zhou, X., Ren, Y., Moore, L., Mei, M., You, Y., Xu, P., Wang, B., Wang, G., Jia, Z., Pu, P. et al. (2010) Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status. Lab. Invest., 90, 144-155.
-
(2010)
Lab. Invest.
, vol.90
, pp. 144-155
-
-
Zhou, X.1
Ren, Y.2
Moore, L.3
Mei, M.4
You, Y.5
Xu, P.6
Wang, B.7
Wang, G.8
Jia, Z.9
Pu, P.10
-
47
-
-
38149139712
-
Frequent loss of PDCD4 expression in human glioma: possible role in the tumorigenesis of glioma
-
Gao, F., Zhang, P., Zhou, C., Li, J., Wang, Q., Zhu, F., Ma, C., Sun, W. and Zhang, L. (2007) Frequent loss of PDCD4 expression in human glioma: possible role in the tumorigenesis of glioma. Oncol. Rep., 17, 123-128.
-
(2007)
Oncol. Rep.
, vol.17
, pp. 123-128
-
-
Gao, F.1
Zhang, P.2
Zhou, C.3
Li, J.4
Wang, Q.5
Zhu, F.6
Ma, C.7
Sun, W.8
Zhang, L.9
-
48
-
-
0037216626
-
The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation
-
Yang, H.S., Jansen, A.P., Komar, A.A., Zheng, X., Merrick, W.C., Costes, S., Lockett, S.J., Sonenberg, N. and Colburn, N.H. (2003) The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol. Cell. Biol., 23, 26-37.
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 26-37
-
-
Yang, H.S.1
Jansen, A.P.2
Komar, A.A.3
Zheng, X.4
Merrick, W.C.5
Costes, S.6
Lockett, S.J.7
Sonenberg, N.8
Colburn, N.H.9
-
49
-
-
0035825611
-
A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation
-
Yang, H.S., Jansen, A.P., Nair, R., Shibahara, K., Verma, A.K., Cmarik, J.L. and Colburn, N.H. (2001) A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation. Oncogene, 20, 669-676.
-
(2001)
Oncogene
, vol.20
, pp. 669-676
-
-
Yang, H.S.1
Jansen, A.P.2
Nair, R.3
Shibahara, K.4
Verma, A.K.5
Cmarik, J.L.6
Colburn, N.H.7
-
50
-
-
8644227794
-
Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1)
-
Goke, R., Barth, P., Schmidt, A., Samans, B. and Lankat-Buttgereit, B. (2004) Programmed cell death protein 4 suppresses CDK1/cdc2 via induction of p21(Waf1/Cip1). Am. J. Physiol. Cell Physiol., 287, C1541-C1546.
-
(2004)
Am. J. Physiol. Cell Physiol.
, vol.287
-
-
Goke, R.1
Barth, P.2
Schmidt, A.3
Samans, B.4
Lankat-Buttgereit, B.5
-
51
-
-
55949114921
-
MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G
-
Chen, Y., Liu, W., Chao, T., Zhang, Y., Yan, X., Gong, Y., Qiang, B., Yuan, J., Sun, M. and Peng, X. (2008) MicroRNA-21 down-regulates the expression of tumor suppressor PDCD4 in human glioblastoma cell T98G. Cancer Lett., 272, 197-205.
-
(2008)
Cancer Lett
, vol.272
, pp. 197-205
-
-
Chen, Y.1
Liu, W.2
Chao, T.3
Zhang, Y.4
Yan, X.5
Gong, Y.6
Qiang, B.7
Yuan, J.8
Sun, M.9
Peng, X.10
-
52
-
-
35148900227
-
MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas
-
Corsten, M.F., Miranda, R., Kasmieh, R., Krichevsky, A.M., Weissleder, R. and Shah, K. (2007) MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res., 67, 8994-9000.
-
(2007)
Cancer Res
, vol.67
, pp. 8994-9000
-
-
Corsten, M.F.1
Miranda, R.2
Kasmieh, R.3
Krichevsky, A.M.4
Weissleder, R.5
Shah, K.6
-
53
-
-
77749279909
-
Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro
-
Ren, Y., Kang, C.S., Yuan, X.B., Zhou, X., Xu, P., Han, L., Wang, G.X., Jia, Z., Zhong, Y., Yu, S. et al. (2010) Co-delivery of as-miR-21 and 5-FU by poly(amidoamine) dendrimer attenuates human glioma cell growth in vitro. J. Biomater. Sci. Polym. Ed., 21, 303-314.
-
(2010)
J. Biomater. Sci. Polym. Ed.
, vol.21
, pp. 303-314
-
-
Ren, Y.1
Kang, C.S.2
Yuan, X.B.3
Zhou, X.4
Xu, P.5
Han, L.6
Wang, G.X.7
Jia, Z.8
Zhong, Y.9
Yu, S.10
-
54
-
-
77349125856
-
MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol
-
Ren, Y., Zhou, X., Mei, M., Yuan, X.B., Han, L., Wang, G.X., Jia, Z.F., Xu, P., Pu, P.Y. and Kang, C.S. (2010) MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol. BMC Cancer, 10, 27.
-
(2010)
BMC Cancer
, vol.10
, pp. 27
-
-
Ren, Y.1
Zhou, X.2
Mei, M.3
Yuan, X.B.4
Han, L.5
Wang, G.X.6
Jia, Z.F.7
Xu, P.8
Pu, P.Y.9
Kang, C.S.10
-
55
-
-
79959795987
-
Phase II study of sunitinib malate in patients with recurrent high-grade glioma
-
Neyns, B., Sadones, J., Chaskis, C., Dujardin, M., Everaert, H., Lv, S., Duerinck, J., Tynninen, O., Nupponen, N., Michotte, A. et al. (2011) Phase II study of sunitinib malate in patients with recurrent high-grade glioma. J. Neurooncol., 103, 491-501.
-
(2011)
J. Neurooncol.
, vol.103
, pp. 491-501
-
-
Neyns, B.1
Sadones, J.2
Chaskis, C.3
Dujardin, M.4
Everaert, H.5
Lv, S.6
Duerinck, J.7
Tynninen, O.8
Nupponen, N.9
Michotte, A.10
-
56
-
-
0004285740
-
-
2nd edn. The MIT Press, Cambridge, MA
-
Banker, G. and Goslin, K. (1998) Culturing Nerve Cells, 2nd edn. pp. 499-542. The MIT Press, Cambridge, MA.
-
(1998)
Culturing Nerve Cells
, pp. 499-542
-
-
Banker, G.1
Goslin, K.2
-
57
-
-
0036580677
-
Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length
-
de Almeida, L.P., Ross, C.A., Zala, D., Aebischer, P. and Deglon, N. (2002) Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length. J. Neurosci., 22, 3473-3483.
-
(2002)
J. Neurosci.
, vol.22
, pp. 3473-3483
-
-
de Almeida, L.P.1
Ross, C.A.2
Zala, D.3
Aebischer, P.4
Deglon, N.5
-
58
-
-
77955290123
-
Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3?
-
Alves, S., Nascimento-Ferreira, I., Dufour, N., Hassig, R., Auregan, G., Nobrega, C., Brouillet, E., Hantraye, P., Pedroso de Lima, M.C., Deglon, N. et al. (2010) Silencing ataxin-3 mitigates degeneration in a rat model of Machado-Joseph disease: no role for wild-type ataxin-3? Hum. Mol. Genet., 19, 2380-2394.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 2380-2394
-
-
Alves, S.1
Nascimento-Ferreira, I.2
Dufour, N.3
Hassig, R.4
Auregan, G.5
Nobrega, C.6
Brouillet, E.7
Hantraye, P.8
Pedroso de Lima, M.C.9
Deglon, N.10
-
59
-
-
83055176904
-
miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production
-
Cardoso, A.L., Guedes, J.R., Pereira de Almeida, L. and Pedroso de Lima, M.C. (2012) miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production. Immunology, 135, 73-88.
-
(2012)
Immunology
, vol.135
, pp. 73-88
-
-
Cardoso, A.L.1
Guedes, J.R.2
Pereira de Almeida, L.3
Pedroso de Lima, M.C.4
-
60
-
-
84868491254
-
Expression of miRNAs and PTEN in endometrial specimens ranging from histologically normal to hyperplasia and endometrial adenocarcinoma
-
Lee, H., Choi, H.J., Kang, C.S., Lee, H.J., Lee, W.S. and Park, C.S. (2012) Expression of miRNAs and PTEN in endometrial specimens ranging from histologically normal to hyperplasia and endometrial adenocarcinoma. Mod. Pathol., 25, 1508-1515.
-
(2012)
Mod. Pathol.
, vol.25
, pp. 1508-1515
-
-
Lee, H.1
Choi, H.J.2
Kang, C.S.3
Lee, H.J.4
Lee, W.S.5
Park, C.S.6
-
61
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl, M.W. (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res., 29, e45.
-
(2001)
Nucleic Acids Res
, vol.29
-
-
Pfaffl, M.W.1
-
62
-
-
78650658398
-
Neuropeptide Y modulation of interleukin-1{beta} (IL-1{beta})-induced nitric oxide production in microglia
-
Ferreira, R., Xapelli, S., Santos, T., Silva, A.P., Cristovao, A., Cortes, L. and Malva, J.O. (2010) Neuropeptide Y modulation of interleukin-1{beta} (IL-1{beta})-induced nitric oxide production in microglia. J. Biol. Chem., 285, 41921-41934.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 41921-41934
-
-
Ferreira, R.1
Xapelli, S.2
Santos, T.3
Silva, A.P.4
Cristovao, A.5
Cortes, L.6
Malva, J.O.7
-
63
-
-
59349089292
-
miRNA in situ hybridization in formaldehyde and EDC-fixed tissues
-
Pena, J.T., Sohn-Lee, C., Rouhanifard, S.H., Ludwig, J., Hafner, M., Mihailovic, A., Lim, C., Holoch, D., Berninger, P., Zavolan, M. et al. (2009) miRNA in situ hybridization in formaldehyde and EDC-fixed tissues. Nat. Methods, 6, 139-141.
-
(2009)
Nat. Methods
, vol.6
, pp. 139-141
-
-
Pena, J.T.1
Sohn-Lee, C.2
Rouhanifard, S.H.3
Ludwig, J.4
Hafner, M.5
Mihailovic, A.6
Lim, C.7
Holoch, D.8
Berninger, P.9
Zavolan, M.10
-
64
-
-
0033856957
-
Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
-
O'Brien, J., Wilson, I., Orton, T. and Pognan, F. (2000) Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur. J. Biochem., 267, 5421-5426.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 5421-5426
-
-
O'Brien, J.1
Wilson, I.2
Orton, T.3
Pognan, F.4
-
65
-
-
0001677717
-
Controlling the false discovery rate - a practical and powerful approach to multiple testing
-
Benjamini, Y. and Hochberg, Y. (1995) Controlling the false discovery rate - a practical and powerful approach to multiple testing. J. Roy. Statist. Soc. Ser. B, 57, 289-300.
-
(1995)
J. Roy. Statist. Soc. Ser. B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
|