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Volumn 6, Issue 4, 2006, Pages 259-269

Oncomirs - MicroRNAs with a role in cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; COMPLEMENTARY RNA; LET 7 PROTEIN; MICRORNA; MIR 1 PROTEIN; MIR 143 PROTEIN; MIR 145 PROTEIN; MIR 15 PROTEIN; MIR 15A PROTEIN; MIR 16 1 PROTEIN; MIR 16 PROTEIN; MIR 181 PROTEIN; MIR 196 PROTEIN; MIR 221 PROTEIN; MIR 222 PROTEIN; MIR 273 PROTEIN; MIR 375 PROTEIN; MIR 430 PROTEIN; UNCLASSIFIED DRUG;

EID: 33645294070     PISSN: 1474175X     EISSN: None     Source Type: Journal    
DOI: 10.1038/nrc1840     Document Type: Review
Times cited : (6478)

References (132)
  • 1
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004). An excellent review of plant and animal miRNAs that discusses how miRNAs differ from siRNAs.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 2
    • 0037062951 scopus 로고    scopus 로고
    • RNA interference
    • Hannon, G. J. RNA interference. Nature 418, 244-251 (2002).
    • (2002) Nature , vol.418 , pp. 244-251
    • Hannon, G.J.1
  • 3
    • 0037144457 scopus 로고    scopus 로고
    • Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA
    • Llave, C., Xie, Z., Kasschau, K. D. & Carrington, J. C. Cleavage of Scarecrow-like mRNA targets directed by a class of Arabidopsis miRNA. Science 297, 2053-2056 (2002).
    • (2002) Science , vol.297 , pp. 2053-2056
    • Llave, C.1    Xie, Z.2    Kasschau, K.D.3    Carrington, J.C.4
  • 4
    • 0141493493 scopus 로고    scopus 로고
    • Control of leaf morphogenesis by microRNAs
    • Palatnik, J. F. et al. Control of leaf morphogenesis by microRNAs. Nature 425, 257-263 (2003).
    • (2003) Nature , vol.425 , pp. 257-263
    • Palatnik, J.F.1
  • 5
    • 0037224921 scopus 로고    scopus 로고
    • A biochemical framework for RNA silencing in plants
    • Tang, G., Reinhart, B. J., Bartel, D. P. & Zamore, P. D. A biochemical framework for RNA silencing in plants. Genes Dev. 17, 49-63 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 49-63
    • Tang, G.1    Reinhart, B.J.2    Bartel, D.P.3    Zamore, P.D.4
  • 6
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • Yekta, S., Shih, I. H. & Bartel, D. P. MicroRNA-directed cleavage of HOXB8 mRNA. Science 304, 594-596 (2004).
    • (2004) Science , vol.304 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 7
    • 0036828639 scopus 로고    scopus 로고
    • The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
    • Carmell, M. A., Xuan, Z., Zhang, M. Q. & Hannon, G. J. The Argonaute family: tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes Dev. 16, 2733-2742 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 2733-2742
    • Carmell, M.A.1    Xuan, Z.2    Zhang, M.Q.3    Hannon, G.J.4
  • 8
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee, R. C., Feinbaum, R. L. & Ambros, V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75, 843-854 (1993).
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 9
    • 0027730383 scopus 로고
    • Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
    • Wightman, B., Ha, I. & Ruvkun, G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 75, 855-862 (1993).
    • (1993) Cell , vol.75 , pp. 855-862
    • Wightman, B.1    Ha, I.2    Ruvkun, G.3
  • 10
    • 0033572284 scopus 로고    scopus 로고
    • The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation
    • Olsen, P. H. & Ambros, V. The lin-4 regulatory RNA controls developmental timing in Caenorhabditis elegans by blocking LIN-14 protein synthesis after the initiation of translation. Dev. Biol. 216, 671-680 (1999).
    • (1999) Dev. Biol. , vol.216 , pp. 671-680
    • Olsen, P.H.1    Ambros, V.2
  • 11
    • 0033935425 scopus 로고    scopus 로고
    • Control of developmental timing in Caenorhabditis elegans
    • Ambros, V. Control of developmental timing in Caenorhabditis elegans. Curr. Opin. Genet. Dev. 10, 428-433 (2000).
    • (2000) Curr. Opin. Genet. Dev. , vol.10 , pp. 428-433
    • Ambros, V.1
  • 12
    • 0034708122 scopus 로고    scopus 로고
    • The 21 nucleotide let-7 RNA regulates C. elegans developmental timing
    • Reinhart, B. et al. The 21 nucleotide let-7 RNA regulates C. elegans developmental timing. Nature 403, 901-906 (2000).
    • (2000) Nature , vol.403 , pp. 901-906
    • Reinhart, B.1
  • 13
    • 0033634943 scopus 로고    scopus 로고
    • The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the lin-29 transcription factor
    • Slack, F. J. et al. The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the lin-29 transcription factor. Mol. Cell 5, 659-669 (2000).
    • (2000) Mol. Cell , vol.5 , pp. 659-669
    • Slack, F.J.1
  • 14
    • 0036437372 scopus 로고    scopus 로고
    • Control of developmental timing by microRNAs and their targets
    • Pasquinelli, A. E. & Ruvkun, G. Control of developmental timing by microRNAs and their targets. Annu. Rev. Cell Dev. Biol. 18, 495-513 (2002).
    • (2002) Annu. Rev. Cell Dev. Biol. , vol.18 , pp. 495-513
    • Pasquinelli, A.E.1    Ruvkun, G.2
  • 15
    • 0038708326 scopus 로고    scopus 로고
    • The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs
    • Abrahante, J. E. et al. The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. Dev. Cell 4, 625-637 (2003).
    • (2003) Dev. Cell , vol.4 , pp. 625-637
    • Abrahante, J.E.1
  • 16
    • 0037693842 scopus 로고    scopus 로고
    • The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target
    • Lin, S. Y. et al. The C elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target. Dev. Cell 4, 639-650 (2003).
    • (2003) Dev. Cell , vol.4 , pp. 639-650
    • Lin, S.Y.1
  • 17
    • 0037418839 scopus 로고    scopus 로고
    • Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
    • Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B. & Cohen, S. M. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113, 25-36 (2003).
    • (2003) Cell , vol.113 , pp. 25-36
    • Brennecke, J.1    Hipfner, D.R.2    Stark, A.3    Russell, R.B.4    Cohen, S.M.5
  • 18
    • 24644480213 scopus 로고    scopus 로고
    • Inhibition of translational initiation by let-7 microRNA in human cells
    • Pillai, R. S. et al. Inhibition of translational initiation by let-7 microRNA in human cells. Science 309, 1573-1576 (2005).
    • (2005) Science , vol.309 , pp. 1573-1576
    • Pillai, R.S.1
  • 19
    • 23944514849 scopus 로고    scopus 로고
    • Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation
    • Bagga, S. et al. Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation. Cell 122, 553-563 (2005).
    • (2005) Cell , vol.122 , pp. 553-563
    • Bagga, S.1
  • 20
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim, L. P. et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433, 769-773 (2005).
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1
  • 21
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Lee, Y., Jeon, K., Lee, J. T, Kim, S. & Kim, V. N. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21, 4663-4670 (2002).
    • (2002) EMBO J. , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3    Kim, S.4    Kim, V.N.5
  • 22
    • 0344668836 scopus 로고    scopus 로고
    • Human let-7 stem-loop precursors harbor features of RNase III cleavage products
    • Basyuk, E., Suavet, F., Doglio, A., Bordonne, R. & Bertrand, E. Human let-7 stem-loop precursors harbor features of RNase III cleavage products. Nucleic Acids Res. 31, 6593-6597 (2003).
    • (2003) Nucleic Acids Res. , vol.31 , pp. 6593-6597
    • Basyuk, E.1    Suavet, F.2    Doglio, A.3    Bordonne, R.4    Bertrand, E.5
  • 23
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Lee, Y. et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 425, 415-419 (2003).
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1
  • 24
    • 0037273432 scopus 로고    scopus 로고
    • Sequence requirements for microRNA processing and function in human cells
    • Zeng, Y. & Cullen, B. R. Sequence requirements for microRNA processing and function in human cells. RNA 9, 112-123 (2003).
    • (2003) RNA , vol.9 , pp. 112-123
    • Zeng, Y.1    Cullen, B.R.2
  • 25
    • 9144225636 scopus 로고    scopus 로고
    • The Microprocessor complex mediates the genesis of microRNAs
    • Gregory, R. I. et al. The Microprocessor complex mediates the genesis of microRNAs. Nature 432, 235-240 (2004).
    • (2004) Nature , vol.432 , pp. 235-240
    • Gregory, R.I.1
  • 26
    • 1842816517 scopus 로고    scopus 로고
    • Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
    • Lee, Y. S. et al. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117, 69-81 (2004).
    • (2004) Cell , vol.117 , pp. 69-81
    • Lee, Y.S.1
  • 27
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • Cai, X., Hagedorn, C. H. & Cullen, B. R. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10, 1957-1966 (2004).
    • (2004) RNA , vol.10 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 28
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • Denli, A. M., Tops, B. B., Plasterk, R. H., Ketting, R. F. & Hannon, G. J. Processing of primary microRNAs by the Microprocessor complex. Nature 432, 231-235 (2004).
    • (2004) Nature , vol.432 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3    Ketting, R.F.4    Hannon, G.J.5
  • 30
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi, R., Qin, Y., Macara, I. G. & Cullen, B. R. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev. 17, 3011-3016 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 31
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack, M. T., Czaplinski, K. & Gorlich, D. Exportin 5 is a RanGTP-dependent dsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10, 185-191 (2004).
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 32
    • 17844364875 scopus 로고    scopus 로고
    • Genes and mechanisms related to RNA interference regulate expression of small temporal RNAs that control C. elegans developmental timing
    • Grishok, A. et al. Genes and mechanisms related to RNA interference regulate expression of small temporal RNAs that control C. elegans developmental timing. Cell 106, 23-34 (2001).
    • (2001) Cell , vol.106 , pp. 23-34
    • Grishok, A.1
  • 33
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvagner, G. et al. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 293, 834-838 (2001).
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvagner, G.1
  • 34
    • 0035887005 scopus 로고    scopus 로고
    • Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
    • Ketting, R. F. et al. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes Dev. 15, 2654-2659 (2001).
    • (2001) Genes Dev. , vol.15 , pp. 2654-2659
    • Ketting, R.F.1
  • 35
    • 0033153413 scopus 로고    scopus 로고
    • The timing of lin-4 RNA accumulation controls the timing of postembryonic developmental events in Caenorhabditis elegans
    • Feinbaum, R. & Ambros, V. The timing of lin-4 RNA accumulation controls the timing of postembryonic developmental events in Caenorhabditis elegans. Dev. Biol. 210, 87-95 (1999).
    • (1999) Dev. Biol. , vol.210 , pp. 87-95
    • Feinbaum, R.1    Ambros, V.2
  • 36
    • 0021771445 scopus 로고
    • Heterochronic mutants of the nematode Caenorhabditis elegans
    • Ambros, V. & Horvitz, H. R. Heterochronic mutants of the nematode Caenorhabditis elegans. Science 226, 409-416 (1984).
    • (1984) Science , vol.226 , pp. 409-416
    • Ambros, V.1    Horvitz, H.R.2
  • 37
    • 0034597777 scopus 로고    scopus 로고
    • Conservation across animal phylogeny of the sequence and temporal regulation of the 21 nucleotide C. elegans let-7 heterochronic regulatory RNA
    • Pasquinelli, A., Reinhart, B., Slack, F., Maller, B. & Ruvkun, G. Conservation across animal phylogeny of the sequence and temporal regulation of the 21 nucleotide C. elegans let-7 heterochronic regulatory RNA. Nature 408, 86-89 (2000).
    • (2000) Nature , vol.408 , pp. 86-89
    • Pasquinelli, A.1    Reinhart, B.2    Slack, F.3    Maller, B.4    Ruvkun, G.5
  • 38
    • 0035955374 scopus 로고    scopus 로고
    • Identification of novel genes coding for small expressed RNAs
    • Lagos-Quintana, M., Rauhut, R., Lendeckel, W. & Tuschl, T. Identification of novel genes coding for small expressed RNAs. Science 294, 853-858 (2001).
    • (2001) Science , vol.294 , pp. 853-858
    • Lagos-Quintana, M.1    Rauhut, R.2    Lendeckel, W.3    Tuschl, T.4
  • 39
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • Lau, N. C., Lim, L. P., Weinstein, E. G. & Bartel, D. P. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 294, 858-862. (2001).
    • (2001) Science , vol.294 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 40
    • 0035955366 scopus 로고    scopus 로고
    • An extensive class of small RNAs in Caenorhabditis elegans
    • Lee, R. C. & Ambros, V. An extensive class of small RNAs in Caenorhabditis elegans. Science 294, 862-864 (2001).
    • (2001) Science , vol.294 , pp. 862-864
    • Lee, R.C.1    Ambros, V.2
  • 41
    • 0037197803 scopus 로고    scopus 로고
    • Identification of tissue-specific microRNAs from mouse
    • Lagos-Quintana, M. et al. Identification of tissue-specific microRNAs from mouse. Curr. Biol. 12, 735-739 (2002).
    • (2002) Curr. Biol. , vol.12 , pp. 735-739
    • Lagos-Quintana, M.1
  • 42
    • 0041941514 scopus 로고    scopus 로고
    • The small RNA profile during Drosophila melanogaster development
    • Aravin, A. A. et al. The small RNA profile during Drosophila melanogaster development. Dev. Cell 5, 337-350 (2003).
    • (2003) Dev. Cell , vol.5 , pp. 337-350
    • Aravin, A.A.1
  • 43
    • 0347357618 scopus 로고    scopus 로고
    • A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans
    • Johnston, R. J. & Hobert, O. A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans. Nature 426, 845-849 (2003).
    • (2003) Nature , vol.426 , pp. 845-849
    • Johnston, R.J.1    Hobert, O.2
  • 45
  • 47
    • 0037447334 scopus 로고    scopus 로고
    • The microRNAs of Caenorhabditis elegans
    • Lim, L. P. et al. The microRNAs of Caenorhabditis elegans. Genes Dev. 17, 991-1008 (2003).
    • (2003) Genes Dev. , vol.17 , pp. 991-1008
    • Lim, L.P.1
  • 48
    • 0037790717 scopus 로고    scopus 로고
    • Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and Broad-Complex gene activity
    • Sempere, L. F., Sokol, N. S., Dubrovsky, E. B., Berger, E. M. & Ambros, V. Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and Broad-Complex gene activity. Dev. Biol. 259, 9-18 (2003).
    • (2003) Dev. Biol. , vol.259 , pp. 9-18
    • Sempere, L.F.1    Sokol, N.S.2    Dubrovsky, E.B.3    Berger, E.M.4    Ambros, V.5
  • 49
    • 0037694970 scopus 로고    scopus 로고
    • The Drosophila microRNA mir-14 suppresses cell death and is required for normal fat metabolism
    • Xu, P., Vernooy, S. Y., Guo, M. & Hay, B. A. The Drosophila microRNA mir-14 suppresses cell death and is required for normal fat metabolism. Curr. Biol. 13, 790-795 (2003).
    • (2003) Curr. Biol. , vol.13 , pp. 790-795
    • Xu, P.1    Vernooy, S.Y.2    Guo, M.3    Hay, B.A.4
  • 50
    • 4043072675 scopus 로고    scopus 로고
    • MicroRNAs act sequentially and asymmetrically to control chemosensory laterally in the nematode
    • Chang, S., Johnston, R. J. Jr, Frokjaer-Jensen, C., Lockery, S. & Hobert, O. MicroRNAs act sequentially and asymmetrically to control chemosensory laterally in the nematode. Nature 430, 785-789 (2004).
    • (2004) Nature , vol.430 , pp. 785-789
    • Chang, S.1    Johnston Jr., R.J.2    Frokjaer-Jensen, C.3    Lockery, S.4    Hobert, O.5
  • 51
    • 11844262661 scopus 로고    scopus 로고
    • Phylogenetic shadowing and computational identification of human microRNA genes
    • Berezikov, E. et al. Phylogenetic shadowing and computational identification of human microRNA genes. Cell 120, 21-24 (2005).
    • (2005) Cell , vol.120 , pp. 21-24
    • Berezikov, E.1
  • 52
    • 22844440427 scopus 로고    scopus 로고
    • Identification of hundreds of conserved and nonconserved human microRNAs
    • Bentwich, I. et al. Identification of hundreds of conserved and nonconserved human microRNAs. Nature Genet. 37, 766-770 (2005).
    • (2005) Nature Genet. , vol.37 , pp. 766-770
    • Bentwich, I.1
  • 53
    • 6344281172 scopus 로고    scopus 로고
    • Identification of mammalian microRNA host genes and transcription units
    • Rodriguez, A., Griffiths-Jones, S., Ashurst, J. L. & Bradley, A. Identification of mammalian microRNA host genes and transcription units. Genome Res. 14, 1902-1910 (2004).
    • (2004) Genome Res. , vol.14 , pp. 1902-1910
    • Rodriguez, A.1    Griffiths-Jones, S.2    Ashurst, J.L.3    Bradley, A.4
  • 54
    • 13944260434 scopus 로고    scopus 로고
    • Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes
    • Baskerville, S. & Bartel, D. P. Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. RNA 11, 241-247 (2005).
    • (2005) RNA , vol.11 , pp. 241-247
    • Baskerville, S.1    Bartel, D.P.2
  • 55
    • 0142165224 scopus 로고    scopus 로고
    • Functional siRNAs and miRNAs exhibit strand bias
    • Khvorova, A., Reynolds, A. & Jayasena, S. D. Functional siRNAs and miRNAs exhibit strand bias. Cell 115, 209-216 (2003).
    • (2003) Cell , vol.115 , pp. 209-216
    • Khvorova, A.1    Reynolds, A.2    Jayasena, S.D.3
  • 56
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • Schwarz, D. S. et al. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115, 199-208 (2003).
    • (2003) Cell , vol.115 , pp. 199-208
    • Schwarz, D.S.1
  • 57
    • 1642374097 scopus 로고    scopus 로고
    • Specificity of microRNA target selection in translational repression
    • Doench, J. G. & Sharp, P. A. Specificity of microRNA target selection in translational repression. Genes Dev. 18, 504-511 (2004).
    • (2004) Genes Dev. , vol.18 , pp. 504-511
    • Doench, J.G.1    Sharp, P.A.2
  • 58
    • 0942301280 scopus 로고    scopus 로고
    • The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′ UTR
    • Vella, M. C., Choi, E. Y., Lin, S. Y., Reinert, K. & Slack, F. J. The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′ UTR. Genes Dev. 18, 132-137 (2004).
    • (2004) Genes Dev. , vol.18 , pp. 132-137
    • Vella, M.C.1    Choi, E.Y.2    Lin, S.Y.3    Reinert, K.4    Slack, F.J.5
  • 60
    • 14644398601 scopus 로고    scopus 로고
    • The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans
    • Grosshans, H., Johnson, T., Reinert, K. L., Gerstein, M. & Slack, F. J. The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. Dev. Cell 8, 321-330 (2005).
    • (2005) Dev. Cell , vol.8 , pp. 321-330
    • Grosshans, H.1    Johnson, T.2    Reinert, K.L.3    Gerstein, M.4    Slack, F.J.5
  • 61
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek, A. et al. Combinatorial microRNA target predictions. Nature Genet. 37, 495-500 (2005).
    • (2005) Nature Genet. , vol.37 , pp. 495-500
    • Krek, A.1
  • 62
    • 4644237189 scopus 로고    scopus 로고
    • Fast and effective prediction of microRNA/target duplexes
    • Rehmsmeier, M., Steffen, P., Hochsmann, M. & Giegerich, R. Fast and effective prediction of microRNA/target duplexes. RNA 10, 1507-1517 (2004).
    • (2004) RNA , vol.10 , pp. 1507-1517
    • Rehmsmeier, M.1    Steffen, P.2    Hochsmann, M.3    Giegerich, R.4
  • 63
    • 14044251458 scopus 로고    scopus 로고
    • Human microRNA targets
    • John, B. et al. Human microRNA targets. PLoS Biol. 2, e363 (2004).
    • (2004) PLoS Biol. , vol.2
    • John, B.1
  • 64
    • 2442672918 scopus 로고    scopus 로고
    • A combined computational-experimental approach predicts human microRNA targets
    • Kiriakidou, M. et al. A combined computational-experimental approach predicts human microRNA targets. Genes Dev. 18, 1165-1178 (2004).
    • (2004) Genes Dev. , vol.18 , pp. 1165-1178
    • Kiriakidou, M.1
  • 65
    • 0842321501 scopus 로고    scopus 로고
    • MicroRNA targets in Drosophila
    • Enright, A. J. et al. MicroRNA targets in Drosophila. Genome Biol. 5, R1 (2003).
    • (2003) Genome Biol. , vol.5
    • Enright, A.J.1
  • 66
    • 1542297345 scopus 로고    scopus 로고
    • Computational identification of microRNA targets
    • Rajewsky, N. & Socci, N. D. Computational identification of microRNA targets. Dev. Biol. 267, 529-535 (2004).
    • (2004) Dev. Biol. , vol.267 , pp. 529-535
    • Rajewsky, N.1    Socci, N.D.2
  • 69
    • 10644253787 scopus 로고    scopus 로고
    • Architecture of a validated microRNA::target interaction
    • Vella, M. C., Reinert, K. & Slack, F. J. Architecture of a validated microRNA::target interaction. Chem. Biol. 11, 1619-1623 (2004).
    • (2004) Chem. Biol. , vol.11 , pp. 1619-1623
    • Vella, M.C.1    Reinert, K.2    Slack, F.J.3
  • 70
    • 4344677175 scopus 로고    scopus 로고
    • Common logic of transcription factor and microRNA action
    • Hobert, O. Common logic of transcription factor and microRNA action. Trends Biochem. Sci. 29, 462-468 (2004).
    • (2004) Trends Biochem. Sci. , vol.29 , pp. 462-468
    • Hobert, O.1
  • 71
    • 20144373433 scopus 로고    scopus 로고
    • Reduced expression of Dicer associated with poor prognosis in lung cancer patients
    • Karube, Y. et al. Reduced expression of Dicer associated with poor prognosis in lung cancer patients. Cancer Sci. 96, 111-115 (2005).
    • (2005) Cancer Sci. , vol.96 , pp. 111-115
    • Karube, Y.1
  • 72
    • 13844294261 scopus 로고    scopus 로고
    • Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing
    • Kanellopoulou, C. et al. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 19, 489-501 (2005).
    • (2005) Genes Dev. , vol.19 , pp. 489-501
    • Kanellopoulou, C.1
  • 73
    • 4143149753 scopus 로고    scopus 로고
    • Dicer is essential for formation of the heterochromatin structure in vertebrate cells
    • Fukagawa, T. et al. Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nature Cell Biol. 6, 784-791 (2004).
    • (2004) Nature Cell Biol. , vol.6 , pp. 784-791
    • Fukagawa, T.1
  • 74
    • 0242266620 scopus 로고    scopus 로고
    • Dicer is essential for mouse development
    • Bernstein, E. et al. Dicer is essential for mouse development. Nature Genet. 35, 215-217 (2003).
    • (2003) Nature Genet. , vol.35 , pp. 215-217
    • Bernstein, E.1
  • 75
    • 23344439006 scopus 로고    scopus 로고
    • The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb
    • Harfe, B. D., McManus, M. T., Mansfield, J. H., Hornstein, E. & Tabin, C. J. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc. Natl Acad. Sci. USA 102, 10898-10903 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 10898-10903
    • Harfe, B.D.1    McManus, M.T.2    Mansfield, J.H.3    Hornstein, E.4    Tabin, C.J.5
  • 76
    • 22944433872 scopus 로고    scopus 로고
    • Aberrant T cell differentiation in the absence of Dicer
    • Muljo, S. A. et al. Aberrant T cell differentiation in the absence of Dicer. J. Exp. Med. 202, 261-269 (2005).
    • (2005) J. Exp. Med. , vol.202 , pp. 261-269
    • Muljo, S.A.1
  • 77
    • 15744391012 scopus 로고    scopus 로고
    • Dicer is required for embryonic angiogenesis during mouse development
    • Yang, W. J. et al. Dicer is required for embryonic angiogenesis during mouse development. J. Biol. Chem. 280, 9330-9335 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 9330-9335
    • Yang, W.J.1
  • 79
    • 0037030522 scopus 로고    scopus 로고
    • Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas
    • Qiao, D., Zeeman, A. M., Deng, W., Looijenga, L. H. & Lin, H. Molecular characterization of hiwi, a human member of the piwi gene family whose overexpression is correlated to seminomas. Oncogene 21, 3988-3999 (2002).
    • (2002) Oncogene , vol.21 , pp. 3988-3999
    • Qiao, D.1    Zeeman, A.M.2    Deng, W.3    Looijenga, L.H.4    Lin, H.5
  • 80
    • 20444440706 scopus 로고    scopus 로고
    • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • Lee, Y. S., Kim, H. K., Chung, S., Kim, K. S. & Dutta, A. Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J. Biol. Chem. 280, 16635-16641 (2005).
    • (2005) J. Biol. Chem. , vol.280 , pp. 16635-16641
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3    Kim, K.S.4    Dutta, A.5
  • 81
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival
    • Takamizawa, J. et al. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res. 64, 3753-3756 (2004). Describes a strong correlation between expression levels of members of the let-7 family and post-operative survival in patients with lung cancer, and therefore supports the notion that let-7 family members function as tumour suppressors.
    • (2004) Cancer Res. , vol.64 , pp. 3753-3756
    • Takamizawa, J.1
  • 82
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • Johnson, S. M. et al. RAS is regulated by the let-7 microRNA family. Cell 120, 635-647 (2005). Implicates a tumour-suppressor role for the let-7 family by directly regulating the expression of the Ras oncogenes.
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1
  • 83
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin, G. A. et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl Acad. Sci. USA 101, 2999-3004 (2004). Reveals that half the annotated human miRNAs are associated with cancer.
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 2999-3004
    • Calin, G.A.1
  • 84
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio, M. V. et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 65, 7065-7070 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 7065-7070
    • Iorio, M.V.1
  • 85
    • 27644442420 scopus 로고    scopus 로고
    • Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia
    • Sonoki, T., Iwanaga, E., Mitsuya, H. & Asou, N. Insertion of microRNA-125b-1, a human homologue of lin-4, into a rearranged immunoglobulin heavy chain gene locus in a patient with precursor B-cell acute lymphoblastic leukemia. Leukemia 19, 2009-2010 (2005).
    • (2005) Leukemia , vol.19 , pp. 2009-2010
    • Sonoki, T.1    Iwanaga, E.2    Mitsuya, H.3    Asou, N.4
  • 86
    • 0036670695 scopus 로고    scopus 로고
    • The bantam gene regulates Drosophila growth
    • Hipfner, D. R., Weigmann, K. & Cohen, S. M. The bantam gene regulates Drosophila growth. Genetics 161, 1527-1537 (2002).
    • (2002) Genetics , vol.161 , pp. 1527-1537
    • Hipfner, D.R.1    Weigmann, K.2    Cohen, S.M.3
  • 87
    • 18244385475 scopus 로고    scopus 로고
    • MicroRNAs regulate brain morphogenesis in zebrafish
    • Giraldez, A. J. et al. MicroRNAs regulate brain morphogenesis in zebrafish. Science 308, 833-838 (2005).
    • (2005) Science , vol.308 , pp. 833-838
    • Giraldez, A.J.1
  • 88
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • Chen, C. Z., Li, L., Lodish, H. F. & Bartel, D. P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303, 83-86 (2004).
    • (2004) Science , vol.303 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 89
    • 9144270691 scopus 로고    scopus 로고
    • A pancreatic islet-specific microRNA regulates insulin secretion
    • Poy, M. N. et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432, 226-230 (2004).
    • (2004) Nature , vol.432 , pp. 226-230
    • Poy, M.N.1
  • 90
    • 10344243662 scopus 로고    scopus 로고
    • MicroRNA-143 regulates adipocyte differentiation
    • Esau, C. et al. MicroRNA-143 regulates adipocyte differentiation. J. Biol. Chem. 279, 52361-52365 (2004).
    • (2004) J. Biol. Chem. , vol.279 , pp. 52361-52365
    • Esau, C.1
  • 91
    • 28444449496 scopus 로고    scopus 로고
    • The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development
    • Hornstein, E. et al. The microRNA miR-196 acts upstream of Hoxb8 and Shh in limb development. Nature 438, 671-674 (2005).
    • (2005) Nature , vol.438 , pp. 671-674
    • Hornstein, E.1
  • 92
    • 22444437609 scopus 로고    scopus 로고
    • Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis
    • Zhao, Y., Samal, E. & Srivastava, D. Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature 436, 214-220 (2005).
    • (2005) Nature , vol.436 , pp. 214-220
    • Zhao, Y.1    Samal, E.2    Srivastava, D.3
  • 93
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin, G. A. et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc. Natl Acad. Sci. USA 99, 15524-15529 (2002). The first report to correlate the mis-expression of miRNAs with cancer.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1
  • 94
    • 25444520537 scopus 로고    scopus 로고
    • MiR-15 and miR-16 induce apoptosis by targeting BCL2
    • Cimmino, A. et al. miR-15 and miR-16 induce apoptosis by targeting BCL2. Proc. Natl Acad. Sci. USA 102, 13944-13949 (2005). Provides evidence that mir-15a and mir-16-1 negatively regulate the BCL2 oncogene.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 13944-13949
    • Cimmino, A.1
  • 95
    • 27244434788 scopus 로고    scopus 로고
    • A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • Calin, G. A. et al. A microRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N. Engl. J. Med. 353, 1793-1801 (2005).
    • (2005) N. Engl. J. Med. , vol.353 , pp. 1793-1801
    • Calin, G.A.1
  • 96
    • 3042752769 scopus 로고    scopus 로고
    • An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues
    • Liu, C. G. et al. An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues. Proc. Natl Acad. Sci. USA 101, 9740-9744 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 9740-9744
    • Liu, C.G.1
  • 97
    • 0142120587 scopus 로고    scopus 로고
    • Reduced accumulation of specific microRNAs in colorectal neoplasia
    • Michael, M. Z., O'Connor, S. M., van Holst Pellekaan, N. G., Young, G. P. & James, R. J. Reduced accumulation of specific microRNAs in colorectal neoplasia. Mol. Cancer Res. 1, 882-891 (2003). Reveals that mir-143 and mir-145 RNA levels are often reduced in colorectal cancer.
    • (2003) Mol. Cancer Res. , vol.1 , pp. 882-891
    • Michael, M.Z.1    O'Connor, S.M.2    Van Holst Pellekaan, N.G.3    Young, G.P.4    James, R.J.5
  • 98
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu, J. et al. MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (2005). Shows that miRNA expression profiles can cluster similar tumour types together more accurately than the expression profiles of protein-coding mRNA genes.
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1
  • 99
    • 14844364472 scopus 로고    scopus 로고
    • Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
    • Cheng, A. M., Byrom, M. W., Shelton, J. & Ford, L. P. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res. 33, 1290-1297 (2005).
    • (2005) Nucleic Acids Res. , vol.33 , pp. 1290-1297
    • Cheng, A.M.1    Byrom, M.W.2    Shelton, J.3    Ford, L.P.4
  • 100
    • 23044464236 scopus 로고    scopus 로고
    • Extensive modulation of a set of microRNAs in primary glioblastoma
    • Ciafre, S. A. et al. Extensive modulation of a set of microRNAs in primary glioblastoma. Biochem. Biophys. Res. Commun. 334, 1351-1358 (2005).
    • (2005) Biochem. Biophys. Res. Commun. , vol.334 , pp. 1351-1358
    • Ciafre, S.A.1
  • 101
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan, J. A., Krichevsky, A. M. & Kosik, K. S. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 65, 6029-6033 (2005). Describes a novel miRNA that functions as an oncogene by modulating the apoptotic pathway.
    • (2005) Cancer Res. , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 102
    • 0037013147 scopus 로고    scopus 로고
    • Suppression of Myc-induced apoptosis in β cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression
    • Pelengaris, S., Khan, M. & Evan, G. I. Suppression of Myc-induced apoptosis in β cells exposes multiple oncogenic properties of Myc and triggers carcinogenic progression. Cell 109, 321-334 (2002).
    • (2002) Cell , vol.109 , pp. 321-334
    • Pelengaris, S.1    Khan, M.2    Evan, G.I.3
  • 103
    • 0024344852 scopus 로고
    • Multiple protooncogene activations in avian leukosis virus-induced lymphomas: Evidence for stage-specific events
    • Clurman, B. E. & Hayward, W. S. Multiple protooncogene activations in avian leukosis virus-induced lymphomas: evidence for stage-specific events. Mol. Cell. Biol. 9, 2657-2664 (1989).
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 2657-2664
    • Clurman, B.E.1    Hayward, W.S.2
  • 104
    • 0031018264 scopus 로고    scopus 로고
    • Bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA
    • Tam, W., Ben-Yehuda, D. & Hayward, W. S. bic, a novel gene activated by proviral insertions in avian leukosis virus-induced lymphomas, is likely to function through its noncoding RNA. Mol. Cell. Biol. 17, 1490-1502 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 1490-1502
    • Tam, W.1    Ben-Yehuda, D.2    Hayward, W.S.3
  • 105
    • 0346727383 scopus 로고    scopus 로고
    • High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma
    • Metzler, M., Wilda, M., Busch, K., Viehmann, S. & Borkhardt, A. High expression of precursor microRNA-155/BIC RNA in children with Burkitt lymphoma. Genes Chromosomes Cancer 39, 167-169 (2004). Identifies an miRNA that resides in the BIC gene, a non-coding RNA that has been found to be preferentially upregulated in Hodgkin lymphoma.
    • (2004) Genes Chromosomes Cancer , vol.39 , pp. 167-169
    • Metzler, M.1    Wilda, M.2    Busch, K.3    Viehmann, S.4    Borkhardt, A.5
  • 106
    • 14844354250 scopus 로고    scopus 로고
    • Accumulation of miR-155 and BIC RNA in human B cell lymphomas
    • Eis, P. S. et al. Accumulation of miR-155 and BIC RNA in human B cell lymphomas. Proc. Natl Acad. Sci. USA 102, 3627-3632 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 3627-3632
    • Eis, P.S.1
  • 107
    • 26044481464 scopus 로고    scopus 로고
    • BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas
    • Kluiver, J. et al. BIC and miR-155 are highly expressed in Hodgkin, primary mediastinal and diffuse large B cell lymphomas. J. Pathol. 207, 243-249 (2005).
    • (2005) J. Pathol. , vol.207 , pp. 243-249
    • Kluiver, J.1
  • 108
    • 0037402495 scopus 로고    scopus 로고
    • High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma
    • van den Berg, A. et al. High expression of B-cell receptor inducible gene BIC in all subtypes of Hodgkin lymphoma. Genes Chromosomes Cancer 37, 20-28 (2003).
    • (2003) Genes Chromosomes Cancer , vol.37 , pp. 20-28
    • Van Den Berg, A.1
  • 109
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He, L. et al. A microRNA polycistron as a potential human oncogene. Nature 435, 828-833 (2005). Shows that the mir-17-92 cluster works together with MYC and accelerates tumour progression in a B-cell lymphoma model.
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1
  • 110
    • 20444479428 scopus 로고    scopus 로고
    • c-Myc-regulated microRNAs modulate E2F1 expression
    • O'Donnell, K. A., Wentzel, E. A., Zeller, K. I., Dang, C. V. & Mendell, J. T. c-Myc-regulated microRNAs modulate E2F1 expression. Nature 435, 839-843 (2005). Reveals that the MYC oncogene induces the expression of the mir-17-92 cluster, and, in turn, the mir-17-92 cluster negatively regulates the MYC-target gene, E2F1, revealing a complex genetic circuit that tightly controls cellular proliferation.
    • (2005) Nature , vol.435 , pp. 839-843
    • O'Donnell, K.A.1    Wentzel, E.A.2    Zeller, K.I.3    Dang, C.V.4    Mendell, J.T.5
  • 111
    • 2342449399 scopus 로고    scopus 로고
    • Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma
    • Ota, A. et al. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res. 64, 3087-3095 (2004).
    • (2004) Cancer Res. , vol.64 , pp. 3087-3095
    • Ota, A.1
  • 112
    • 4143142117 scopus 로고    scopus 로고
    • MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias
    • Calin, G. A. et al. MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc. Natl Acad. Sci. USA 101, 11755-11760 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 11755-11760
    • Calin, G.A.1
  • 113
    • 27644570319 scopus 로고    scopus 로고
    • A microRNA cluster as a target of genomic amplification in malignant lymphoma
    • Tagawa, H. & Seto, M. A microRNA cluster as a target of genomic amplification in malignant lymphoma. Leukemia 19, 2013-2016 (2005).
    • (2005) Leukemia , vol.19 , pp. 2013-2016
    • Tagawa, H.1    Seto, M.2
  • 114
    • 0034018449 scopus 로고    scopus 로고
    • A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcoma
    • Gordon, A. T. et al. A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcoma. Genes Chromosomes Cancer 28, 220-226 (2000).
    • (2000) Genes Chromosomes Cancer , vol.28 , pp. 220-226
    • Gordon, A.T.1
  • 115
    • 18744375476 scopus 로고    scopus 로고
    • Gains of 13q are correlated with a poor prognosis in liposarcoma
    • Schmidt, H. et al. Gains of 13q are correlated with a poor prognosis in liposarcoma. Mod. Pathol. 18, 638-644 (2005).
    • (2005) Mod. Pathol. , vol.18 , pp. 638-644
    • Schmidt, H.1
  • 116
    • 27544495514 scopus 로고    scopus 로고
    • A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation
    • Hayashita, Y. et al. A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 65, 9628-9632 (2005).
    • (2005) Cancer Res. , vol.65 , pp. 9628-9632
    • Hayashita, Y.1
  • 118
    • 0033369354 scopus 로고    scopus 로고
    • Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: Identification of three independent regions
    • Lin, Y. W. et al. Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: identification of three independent regions. Eur. J. Cancer 35, 1730-1734 (1999).
    • (1999) Eur. J. Cancer , vol.35 , pp. 1730-1734
    • Lin, Y.W.1
  • 119
    • 29144440077 scopus 로고    scopus 로고
    • MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation
    • Felli, N. et al. MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation. Proc. Natl Acad. Sci. USA 102, 18081-18086 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 18081-18086
    • Felli, N.1
  • 120
    • 13944283031 scopus 로고    scopus 로고
    • Microarray-based, high-throughput gene expression profiling of microRNAs
    • Nelson, P. T. et al. Microarray-based, high-throughput gene expression profiling of microRNAs. Nature Methods 1, 155-161 (2004).
    • (2004) Nature Methods , vol.1 , pp. 155-161
    • Nelson, P.T.1
  • 121
    • 13944262052 scopus 로고    scopus 로고
    • A custom microarray platform for analysis of microRNA gene expression
    • Thomson, J. M., Parker, J., Perou, C. M. & Hammond, S. M. A custom microarray platform for analysis of microRNA gene expression. Nature Methods 1, 47-53 (2004).
    • (2004) Nature Methods , vol.1 , pp. 47-53
    • Thomson, J.M.1    Parker, J.2    Perou, C.M.3    Hammond, S.M.4
  • 122
    • 0141631876 scopus 로고    scopus 로고
    • A microRNA array reveals extensive regulation of microRNAs during brain development
    • Krichevsky, A. M., King, K. S., Donahue, C. P., Khrapko, K. & Kosik, K. S. A microRNA array reveals extensive regulation of microRNAs during brain development. RNA 9, 1274-1281 (2003).
    • (2003) RNA , vol.9 , pp. 1274-1281
    • Krichevsky, A.M.1    King, K.S.2    Donahue, C.P.3    Khrapko, K.4    Kosik, K.S.5
  • 123
    • 5344273958 scopus 로고    scopus 로고
    • Microarray analysis of microRNA expression in the developing mammalian brain
    • Miska, E. A. et al. Microarray analysis of microRNA expression in the developing mammalian brain. Genome Biol. 5, R68 (2004).
    • (2004) Genome Biol. , vol.5
    • Miska, E.A.1
  • 124
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere, L. F. et al. Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol. 5, R13 (2004).
    • (2004) Genome Biol. , vol.5
    • Sempere, L.F.1
  • 125
    • 18444415448 scopus 로고    scopus 로고
    • Regulation of miRNA expression during neural cell specification
    • Smirnova, L. et al. Regulation of miRNA expression during neural cell specification. Eur. J. Neurosci. 21, 1469-1477 (2005).
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 1469-1477
    • Smirnova, L.1
  • 126
    • 16344383409 scopus 로고    scopus 로고
    • Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs
    • Sun, Y. et al. Development of a micro-array to detect human and mouse microRNAs and characterization of expression in human organs. Nucleic Acids Res. 32, e188 (2004).
    • (2004) Nucleic Acids Res. , vol.32
    • Sun, Y.1
  • 127
    • 24644489402 scopus 로고    scopus 로고
    • MicroRNA profiling of the murine hematopoietic system
    • Monticelli, S. et al. MicroRNA profiling of the murine hematopoietic system. Genome Biol. 6, R71 (2005).
    • (2005) Genome Biol. , vol.6
    • Monticelli, S.1
  • 128
    • 7044285911 scopus 로고    scopus 로고
    • Probing microRNAs with microarrays: Tissue specificity and functional inference
    • Babak, T., Zhang, W., Morris, Q., Blencowe, B. J. & Hughes, T. R. Probing microRNAs with microarrays: tissue specificity and functional inference. RNA 10, 1813-1819 (2004).
    • (2004) RNA , vol.10 , pp. 1813-1819
    • Babak, T.1    Zhang, W.2    Morris, Q.3    Blencowe, B.J.4    Hughes, T.R.5
  • 129
    • 28444469246 scopus 로고    scopus 로고
    • Silencing of microRNAs in vivo with 'antagomirs'
    • Krutzfeldt, J. et al. Silencing of microRNAs in vivo with 'antagomirs'. Natures 438, 685-689 (2005).
    • (2005) Natures , vol.438 , pp. 685-689
    • Krutzfeldt, J.1
  • 130
    • 14644435784 scopus 로고    scopus 로고
    • Short interfering RNAs as a tool for cancer gene therapy
    • Izquierdo, M. Short interfering RNAs as a tool for cancer gene therapy. Cancer Gene Ther. 12, 217-227 (2005).
    • (2005) Cancer Gene Ther. , vol.12 , pp. 217-227
    • Izquierdo, M.1
  • 131
    • 20344371233 scopus 로고    scopus 로고
    • Antisense therapy for cancer
    • Gleave, M. E. & Monia, B. P. Antisense therapy for cancer. Nature Rev. Cancer 5, 468-479 (2005).
    • (2005) Nature Rev. Cancer , vol.5 , pp. 468-479
    • Gleave, M.E.1    Monia, B.P.2
  • 132
    • 30044436911 scopus 로고    scopus 로고
    • The role of microRNA genes in papillary thyroid carcinoma
    • He, H. et al. The role of microRNA genes in papillary thyroid carcinoma. Proc. Natl Acad. Sci. USA 102, 19075-19080 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 19075-19080
    • He, H.1


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