Systemic delivery of tumor suppressor microRNA mimics using a neutral lipid emulsion inhibits lung tumors in mice

Molecular Therapy

Volumn 19, Issue 6, 2011, Pages 1116-1122

  Trang, Phong ^a,b   Wiggins, Jason F ^c   Daige, Christopher L ^c   Cho, Chris ^b   Omotola, Michael ^c   Brown, David ^c   Weidhaas, Joanne B ^b   Bader, Andreas G ^c   Slack, Frank J ^a  

^a YALE UNIVERSITY   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c SYNLOGIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; CRE RECOMBINASE; DIOLEOYLPHOSPHATIDYLCHOLINE; KI 67 ANTIGEN; LIPID EMULSION; LUCIFERASE; MICRORNA; MICRORNA 124; MICRORNA 34; MICRORNA LET 7; POLYSORBATE 20; SMALL INTERFERING RNA; SQUALENE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE MODEL; DRUG DELIVERY SYSTEM; FEMALE; GENE ACTIVATION; INHIBITION KINETICS; LUNG NON SMALL CELL CANCER; MOUSE; NICK END LABELING; NONHUMAN; ONCOGENE K RAS; RNA INTERFERENCE; SINGLE DRUG DOSE; TREATMENT OUTCOME; TUMOR VOLUME; VIRAL GENE DELIVERY SYSTEM;

MAMMALIA; MUS;

EID: 79957900919     PISSN: 15250016     EISSN: 15250024     Source Type: Journal    
DOI: 10.1038/mt.2011.48     Document Type: Article

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