MiR-20a promotes cervical cancer proliferation and metastasis in vitro and in vivo

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Zhao, Shan ^a,b   Yao, Desheng ^a   Chen, Junying ^a   Ding, Nan ^a   Ren, Fei ^a  

^a GUANGXI MEDICAL UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY PROTEIN 7; CELL PROTEIN; MICRORNA 20A; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG; ATG7 PROTEIN, HUMAN; AUTOPHAGY RELATED PROTEIN 7; MICRORNA; MIRN20 MICRORNA, HUMAN; TIMP2 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

3' UNTRANSLATED REGION; ADULT; AGED; APOPTOSIS; ARTICLE; CELL ADHESION; CELL CYCLE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CERVICAL CANCER CELL LINE; COLONY FORMATION; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LENTIVIRINAE; LYMPH NODE METASTASIS; METASTASIS POTENTIAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; TUMOR GROWTH; TUMOR VOLUME; UPREGULATION; UTERINE CERVIX CANCER; WESTERN BLOTTING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METASTASIS; MIDDLE AGED; PATHOLOGY; TUMOR CELL LINE; UTERINE CERVIX; UTERINE CERVIX TUMOR;

LENTIVIRUS;

ADULT; AUTOPHAGY-RELATED PROTEIN 7; CELL LINE, TUMOR; CELL PROLIFERATION; CERVIX UTERI; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; MIDDLE AGED; NEOPLASM METASTASIS; TISSUE INHIBITOR OF METALLOPROTEINASE-2; UBIQUITIN-ACTIVATING ENZYMES; UP-REGULATION; UTERINE CERVICAL NEOPLASMS;

EID: 84925667016     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0120905     Document Type: Article

References (16)

1. Ili CG, Brebi P, Lopez J, Garcia P, Leal P, Suarez E, et al. Genotyping of human papillomavirus in cervical intraepithelial neoplasia in a high-risk population. J Med Virol. 2011; 83: 833-837. doi: 10.1002/jmv.22057 PMID: 21360550
2. Lee RC, Feinbaum RL, Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993; 75: 843-854. PMID: 8252621
3. Zhao Y, Srivastava D. A developmental view of microRNA function. Trends Biochem Sci. 2007; 32: 189-197. PMID: 17350266
4. Ventura A, Young AG, Winslow MM, Lintault L, Meissner A, Erkeland SJ, et al. Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell. 2008; 132: 875-886. doi: 10.1016/j.cell.2008.02.019 PMID: 18329372
5. Zhang J, Wu H, Li P, Zhao Y, Liu M, Tang H. NF-kappaB-modulated miR-130a targets TNF-alpha in cervical cancer cells. J Transl Med. 2014; 12: 155. doi: 10.1186/1479-5876-12-155 PMID: 24885472
6. Wen SY, Lin Y, Yu YQ, Cao SJ, Zhang R, Yang XM, et al. miR-506 acts as a tumor suppressor by directly targeting the hedgehog pathway transcription factor Gli3 in human cervical cancer. Oncogene. 2015; 34717-725.:
7. He L, Thomson JM, Hemann MT, Hernando-Monge E, Mu D, Goodson S, et al. A microRNA polycistron as a potential human oncogene. Nature. 2005; 435: 828-833. PMID: 15944707
8. Tanzer A, Stadler PF. Molecular evolution of a microRNA cluster. J Mol Biol. 2004; 339: 327-335. PMID: 15136036
9. Ota A, Tagawa H, Karnan S, Tsuzuki S, Karpas A, Yoshida Y, et al. Identification and characterization of a novel gene, C13orf25, as a target for 13q31-q32 amplification in malignant lymphoma. Cancer Res. 2004; 64: 3087-3095. PMID: 15126345
10. Chang Y, Liu C, Yang J, Liu G, Feng F, Tang J, et al. MiR-20a triggers metastasis of gallbladder carcinoma. J Hepatol. 2013; 59: 518-527. doi: 10.1016/j.jhep.2013.04.034 PMID: 23665284
11. Zhang JX, Song W, Chen ZH, Wei JH, Liao YJ, Lei J, et al. Prognostic and predictive value of a micro-RNA signature in stage II colon cancer: a microRNA expression analysis. Lancet Oncol. 2013; 14: 1295-1306. doi: 10.1016/S1470-2045(13)70491-1 PMID: 24239208
12. Yonekawa T, Thorburn A. Autophagy and cell death. Essays Biochem. 2013; 55: 105-117. doi: 10.1042/bse0550105 PMID: 24070475
13. Galluzzi L, Vitale I, Abrams JM, Alnemri ES, Baehrecke EH, Blagosklonny MV, et al. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ. 2012; 19: 107-120. doi: 10.1038/cdd.2011.96 PMID: 21760595
14. Weidberg H, Shvets E, Elazar Z. Biogenesis and cargo selectivity of autophagosomes. Annu Rev Biochem. 2011; 80: 125-156. doi: 10.1146/annurev-biochem-052709-094552 PMID: 21548784
15. Inami Y, Waguri S, Sakamoto A, Kouno T, Nakada K, Hino O, et al. (2011) Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells. J Cell Biol. 193: 275-284. doi: 10.1083/jcb.201102031 PMID: 21482715
16. Davies KJ. The Complex Interaction of Matrix Metalloproteinases in the Migration of Cancer Cells through Breast Tissue Stroma. Int J Breast Cancer. 2014; 2014: 839094. doi: 10.1155/2014/839094 PMID: 24800085