-
1
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel DP. (2004). MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
2
-
-
33846283385
-
The evolution of gene regulation by transcription factors and microRNAs
-
Chen K, Rajewsky N. (2007). The evolution of gene regulation by transcription factors and microRNAs. Nat Rev Genet 8: 93-103.
-
(2007)
Nat Rev Genet
, vol.8
, pp. 93-103
-
-
Chen, K.1
Rajewsky, N.2
-
3
-
-
72649084669
-
Differential expression profiling of micro-RNAs and their potential involvement in renal cell carcinoma pathogenesis
-
Chow TF YY, Lianidou E, Romaschin AD, Honey RJ, Stewart R, Pace KT et al. (2009). Differential expression profiling of micro-RNAs and their potential involvement in renal cell carcinoma pathogenesis. Clin Biochem 43: 150-158.
-
(2009)
Clin Biochem
, vol.43
, pp. 150-158
-
-
Chow, T.F.Y.Y.1
Lianidou, E.2
Romaschin, A.D.3
Honey, R.J.4
Stewart, R.5
Pace, K.T.6
-
4
-
-
9144224451
-
Processing of primary microRNAs by the microprocessor complex
-
Denli AM, Tops BB, Plasterk RH, Ketting RF, Hannon GJ. (2004). Processing of primary microRNAs by the microprocessor complex. Nature 432: 231-235.
-
(2004)
Nature
, vol.432
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
Ketting, R.F.4
Hannon, G.J.5
-
5
-
-
0035266127
-
Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species
-
Donald SP, Sun XY, Hu CA, Yu J, Mei JM, Valle D et al. (2001). Proline oxidase, encoded by p53-induced gene-6, catalyzes the generation of proline-dependent reactive oxygen species. Cancer Res 61: 1810-1815.
-
(2001)
Cancer Res
, vol.61
, pp. 1810-1815
-
-
Donald, S.P.1
Sun, X.Y.2
Hu, C.A.3
Yu, J.4
Mei, J.M.5
Valle, D.6
-
6
-
-
65549115615
-
MiR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon
-
Gandellini P, Folini M, Longoni N, Pennati M, Binda M, Colecchia M et al. (2009). miR-205 Exerts tumor-suppressive functions in human prostate through down-regulation of protein kinase Cepsilon. Cancer Res 69: 2287-2295.
-
(2009)
Cancer Res
, vol.69
, pp. 2287-2295
-
-
Gandellini, P.1
Folini, M.2
Longoni, N.3
Pennati, M.4
Binda, M.5
Colecchia, M.6
-
7
-
-
64749116346
-
C-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
-
Gao P, Tchernyshyov I, Chang TC, Lee YS, Kita K, Ochi T et al. (2009). c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature 458: 762-765.
-
(2009)
Nature
, vol.458
, pp. 762-765
-
-
Gao, P.1
Tchernyshyov, I.2
Chang, T.C.3
Lee, Y.S.4
Kita, K.5
Ochi, T.6
-
8
-
-
0035104991
-
P53 mutations and other prognostic factors of renal cell carcinoma
-
Girgin C, Tarhan H, Hekimgil M, Sezer A, Gurel G. (2001). P53 mutations and other prognostic factors of renal cell carcinoma. Urol Int 66: 78-83.
-
(2001)
Urol Int
, vol.66
, pp. 78-83
-
-
Girgin, C.1
Tarhan, H.2
Hekimgil, M.3
Sezer, A.4
Gurel, G.5
-
9
-
-
34548388833
-
Micro-RNA profiling in kidney and bladder cancers
-
Gottardo F, Liu CG, Ferracin M, Calin GA, Fassan M, Bassi P et al. (2007). Micro-RNA profiling in kidney and bladder cancers. UrolOncol 25: 387-392.
-
(2007)
UrolOncol
, vol.25
, pp. 387-392
-
-
Gottardo, F.1
Liu, C.G.2
Ferracin, M.3
Calin, G.A.4
Fassan, M.5
Bassi, P.6
-
10
-
-
9144225636
-
The microprocessor complex mediates the genesis of MicroRNAs
-
Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N et al. (2004). The microprocessor complex mediates the genesis of microRNAs. Nature 432: 235-240.
-
(2004)
Nature
, vol.432
, pp. 235-240
-
-
Gregory, R.I.1
Yan, K.P.2
Amuthan, G.3
Chendrimada, T.4
Doratotaj, B.5
Cooch, N.6
-
11
-
-
64649083602
-
Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis
-
Guimbellot JS, Erickson SW, Mehta T, Wen H, Page GP, Sorscher EJ et al. (2009). Correlation of microRNA levels during hypoxia with predicted target mRNAs through genome-wide microarray analysis. BMC Med Genomics 2: 15.
-
(2009)
BMC Med Genomics
, vol.2
, pp. 15
-
-
Guimbellot, J.S.1
Erickson, S.W.2
Mehta, T.3
Wen, H.4
Page, G.P.5
Sorscher, E.J.6
-
12
-
-
23844555119
-
MicroRNA gene expression deregulation in human breast cancer
-
Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S et al. (2005). MicroRNA gene expression deregulation in human breast cancer. Cancer Res 65: 7065-7070.
-
(2005)
Cancer Res
, vol.65
, pp. 7065-7070
-
-
Iorio, M.V.1
Ferracin, M.2
Liu, C.G.3
Veronese, A.4
Spizzo, R.5
Sabbioni, S.6
-
13
-
-
20044395613
-
RAS is regulated by the let-7 microRNA family
-
Johnson SM, Grosshans H, Shingara J, Byrom M, Jarvis R, Cheng A et al. (2005). RAS is regulated by the let-7 microRNA family. Cell 120: 635-647.
-
(2005)
Cell
, vol.120
, pp. 635-647
-
-
Johnson, S.M.1
Grosshans, H.2
Shingara, J.3
Byrom, M.4
Jarvis, R.5
Cheng, A.6
-
14
-
-
65949112237
-
Treatment of kidney cancer: Insights provided by the VHL tumor-suppressor protein
-
Kaelin Jr WG. (2009). Treatment of kidney cancer: insights provided by the VHL tumor-suppressor protein. Cancer 115: 2262-2272.
-
(2009)
Cancer
, vol.115
, pp. 2262-2272
-
-
Kaelin Jr., W.G.1
-
15
-
-
48849095238
-
MicroRNA miR-199a regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2)
-
Kim S, Lee UJ, Kim MN, Lee EJ, Kim JY, Lee MY et al. (2008). MicroRNA miR-199a regulates the MET proto-oncogene and the downstream extracellular signal-regulated kinase 2 (ERK2). J Biol Chem 283: 18158-18166.
-
(2008)
J Biol Chem
, vol.283
, pp. 18158-18166
-
-
Kim, S.1
Lee, U.J.2
Kim, M.N.3
Lee, E.J.4
Kim, J.Y.5
Lee, M.Y.6
-
16
-
-
0036528246
-
Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein
-
Kondo K, Klco J, Nakamura E, Lechpammer M, Kaelin Jr WG. (2002). Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein. Cancer Cell 1: 237-246.
-
(2002)
Cancer Cell
, vol.1
, pp. 237-246
-
-
Kondo, K.1
Klco, J.2
Nakamura, E.3
Lechpammer, M.4
Kaelin Jr., W.G.5
-
18
-
-
33847234988
-
A microRNA signature of hypoxia
-
Kulshreshtha R, Ferracin M, Wojcik SE, Garzon R, Alder H, Agosto-Perez FJ et al. (2007). A microRNA signature of hypoxia. Mol Cell Biol 27: 1859-1867.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1859-1867
-
-
Kulshreshtha, R.1
Ferracin, M.2
Wojcik, S.E.3
Garzon, R.4
Alder, H.5
Agosto-Perez, F.J.6
-
19
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. (2005). Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
20
-
-
13944282215
-
Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
-
Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J et al. (2005). Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433: 769-773.
-
(2005)
Nature
, vol.433
, pp. 769-773
-
-
Lim, L.P.1
Lau, N.C.2
Garrett-Engele, P.3
Grimson, A.4
Schelter, J.M.5
Castle, J.6
-
21
-
-
69249123718
-
Proline oxidase functions as a mitochondrial tumor suppressor in human cancers
-
Liu Y, Borchert GL, Donald SP, Diwan BA, Anver M, Phang JM. (2009). Proline oxidase functions as a mitochondrial tumor suppressor in human cancers. Cancer Res 69: 6414-6422.
-
(2009)
Cancer Res
, vol.69
, pp. 6414-6422
-
-
Liu, Y.1
Borchert, G.L.2
Donald, S.P.3
Diwan, B.A.4
Anver, M.5
Phang, J.M.6
-
22
-
-
24944529262
-
MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells
-
Liu Y, Borchert GL, Donald SP, Surazynski A, Hu CA, Weydert CJ et al. (2005). MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells. Carcinogenesis 26: 1335-1342.
-
(2005)
Carcinogenesis
, vol.26
, pp. 1335-1342
-
-
Liu, Y.1
Borchert, G.L.2
Donald, S.P.3
Surazynski, A.4
Hu, C.A.5
Weydert, C.J.6
-
23
-
-
33748671329
-
Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: The role of ROS/superoxides, NFAT and MEK/ERK signaling
-
Liu Y, Borchert GL, Surazynski A, Hu CA, Phang JM. (2006). Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling. Oncogene 25: 5640-5647.
-
(2006)
Oncogene
, vol.25
, pp. 5640-5647
-
-
Liu, Y.1
Borchert, G.L.2
Surazynski, A.3
Hu, C.A.4
Phang, J.M.5
-
24
-
-
56249120580
-
Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers
-
Liu Y, Borchert GL, Surazynski A, Phang JM. (2008). Proline oxidase, a p53-induced gene, targets COX-2/PGE2 signaling to induce apoptosis and inhibit tumor growth in colorectal cancers. Oncogene 27: 6729-6737.
-
(2008)
Oncogene
, vol.27
, pp. 6729-6737
-
-
Liu, Y.1
Borchert, G.L.2
Surazynski, A.3
Phang, J.M.4
-
25
-
-
49749126791
-
Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer
-
Lodygin D, Tarasov V, Epanchintsev A, Berking C, Knyazeva T, Korner H et al. (2008). Inactivation of miR-34a by aberrant CpG methylation in multiple types of cancer. Cell Cycle 7: 2591-2600.
-
(2008)
Cell Cycle
, vol.7
, pp. 2591-2600
-
-
Lodygin, D.1
Tarasov, V.2
Epanchintsev, A.3
Berking, C.4
Knyazeva, T.5
Korner, H.6
-
26
-
-
35148886434
-
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
-
Ma L, Teruya-Feldstein J, Weinberg RA. (2007). Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature 449: 682-688.
-
(2007)
Nature
, vol.449
, pp. 682-688
-
-
Ma, L.1
Teruya-Feldstein, J.2
Weinberg, R.A.3
-
27
-
-
0036527785
-
The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma
-
Maranchie JK, Vasselli JR, Riss J, Bonifacino JS, Linehan WM, Klausner RD. (2002). The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma. Cancer Cell 1: 247-255.
-
(2002)
Cancer Cell
, vol.1
, pp. 247-255
-
-
Maranchie, J.K.1
Vasselli, J.R.2
Riss, J.3
Bonifacino, J.S.4
Linehan, W.M.5
Klausner, R.D.6
-
28
-
-
0038322048
-
Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas
-
Maxwell SA, Rivera A. (2003). Proline oxidase induces apoptosis in tumor cells, and its expression is frequently absent or reduced in renal carcinomas. J Biol Chem 278: 9784-9789.
-
(2003)
J Biol Chem
, vol.278
, pp. 9784-9789
-
-
Maxwell, S.A.1
Rivera, A.2
-
29
-
-
57749110627
-
MicroRNAs impair MET-mediated invasive growth
-
Migliore C, Petrelli A, Ghiso E, Corso S, Capparuccia L, Eramo A et al. (2008). MicroRNAs impair MET-mediated invasive growth. Cancer Res 68: 10128-10136.
-
(2008)
Cancer Res
, vol.68
, pp. 10128-10136
-
-
Migliore, C.1
Petrelli, A.2
Ghiso, E.3
Corso, S.4
Capparuccia, L.5
Eramo, A.6
-
30
-
-
33748587841
-
A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes
-
Miranda KC, Huynh T, Tay Y, Ang YS, Tam WL, Thomson AM et al. (2006). A pattern-based method for the identification of microRNA binding sites and their corresponding heteroduplexes. Cell 126: 1203-1217.
-
(2006)
Cell
, vol.126
, pp. 1203-1217
-
-
Miranda, K.C.1
Huynh, T.2
Tay, Y.3
Ang, Y.S.4
Tam, W.L.5
Thomson, A.M.6
-
31
-
-
57149115765
-
Genome-wide microRNA expression profiling in renal cell carcinoma: Significant down-regulation of miR-141 and miR-200c
-
Nakada C, Matsuura K, Tsukamoto Y, Tanigawa M, Yoshimoto T, Narimatsu T et al. (2008). Genome-wide microRNA expression profiling in renal cell carcinoma: significant down-regulation of miR-141 and miR-200c. J Pathol 216: 418-427.
-
(2008)
J Pathol
, vol.216
, pp. 418-427
-
-
Nakada, C.1
Matsuura, K.2
Tsukamoto, Y.3
Tanigawa, M.4
Yoshimoto, T.5
Narimatsu, T.6
-
32
-
-
66949150988
-
MiR-92b and miR-9/9 are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors
-
Nass D, Rosenwald S, Meiri E, Gilad S, Tabibian-Keissar H, Schlosberg A et al. (2009). MiR-92b and miR-9/9 are specifically expressed in brain primary tumors and can be used to differentiate primary from metastatic brain tumors. Brain Pathol 19: 375-383.
-
(2009)
Brain Pathol
, vol.19
, pp. 375-383
-
-
Nass, D.1
Rosenwald, S.2
Meiri, E.3
Gilad, S.4
Tabibian-Keissar, H.5
Schlosberg, A.6
-
33
-
-
65249186793
-
The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors
-
Northcott PA, Fernandez LA, Hagan JP, Ellison DW, Grajkowska W, Gillespie Y et al. (2009). The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors. Cancer Res 69: 3249-3255.
-
(2009)
Cancer Res
, vol.69
, pp. 3249-3255
-
-
Northcott, P.A.1
Fernandez, L.A.2
Hagan, J.P.3
Ellison, D.W.4
Grajkowska, W.5
Gillespie, Y.6
-
34
-
-
33644850483
-
Proline oxidase, a proapoptotic gene, is induced by troglitazone: Evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms
-
Pandhare J, Cooper SK, Phang JM. (2006). Proline oxidase, a proapoptotic gene, is induced by troglitazone: evidence for both peroxisome proliferator-activated receptor gamma-dependent and -independent mechanisms. J Biol Chem 281: 2044-2052.
-
(2006)
J Biol Chem
, vol.281
, pp. 2044-2052
-
-
Pandhare, J.1
Cooper, S.K.2
Phang, J.M.3
-
35
-
-
0021994031
-
The regulatory functions of proline and pyrroline-5-carboxylic acid
-
Phang JM. (1985). The regulatory functions of proline and pyrroline-5-carboxylic acid. Curr Top Cell Regul 25: 91-132.
-
(1985)
Curr Top Cell Regul
, vol.25
, pp. 91-132
-
-
Phang, J.M.1
-
36
-
-
54749113722
-
The metabolism of proline as microenvironmental stress substrate
-
Phang JM, Pandhare J, Liu Y. (2008). The metabolism of proline as microenvironmental stress substrate. J Nutr 138: 2008S-2015S.
-
(2008)
J Nutr
, vol.138
-
-
Phang, J.M.1
Pandhare, J.2
Liu, Y.3
-
37
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak K, Xia Y, Zweier JL, Kinzler KW, Vogelstein B. (1997). A model for p53-induced apoptosis. Nature 389: 300-305.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
38
-
-
65349117540
-
Clinical implications of hypoxia inducible factor in renal cell carcinoma
-
Smaldone MC, Maranchie JK. (2009). Clinical implications of hypoxia inducible factor in renal cell carcinoma. Urol Oncol 27: 238-245.
-
(2009)
Urol Oncol
, vol.27
, pp. 238-245
-
-
Smaldone, M.C.1
Maranchie, J.K.2
-
39
-
-
0141988698
-
Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia
-
Sowter HM, Raval RR, Moore JW, Ratcliffe PJ, Harris AL. (2003). Predominant role of hypoxia-inducible transcription factor (Hif)-1alpha versus Hif-2alpha in regulation of the transcriptional response to hypoxia. Cancer Res 63: 6130-6134.
-
(2003)
Cancer Res
, vol.63
, pp. 6130-6134
-
-
Sowter, H.M.1
Raval, R.R.2
Moore, J.W.3
Ratcliffe, P.J.4
Harris, A.L.5
-
40
-
-
0026534279
-
Infrequent mutation of p53 gene in human renal cell carcinoma detected by polymerase chain reaction single-strand conformation polymorphism analysis
-
Suzuki Y, Tamura G, Satodate R, Fujioka T. (1992). Infrequent mutation of p53 gene in human renal cell carcinoma detected by polymerase chain reaction single-strand conformation polymorphism analysis. Jpn J Cancer Res 83: 233-235.
-
(1992)
Jpn J Cancer Res
, vol.83
, pp. 233-235
-
-
Suzuki, Y.1
Tamura, G.2
Satodate, R.3
Fujioka, T.4
-
41
-
-
39749110034
-
Functional aspects of animal microRNAs
-
Williams AE. (2008). Functional aspects of animal microRNAs. Cell Mol Life Sci 65: 545-562.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 545-562
-
-
Williams, A.E.1
-
42
-
-
39049086391
-
MicroRNA expression profiling in human ovarian cancer: MiR-214 induces cell survival and cisplatin resistance by targeting PTEN
-
Yang H, Kong W, He L, Zhao JJ, ODonnell JD, Wang J et al. (2008). MicroRNA expression profiling in human ovarian cancer: miR-214 induces cell survival and cisplatin resistance by targeting PTEN. Cancer Res 68: 425-433.
-
(2008)
Cancer Res
, vol.68
, pp. 425-433
-
-
Yang, H.1
Kong, W.2
He, L.3
Zhao, J.J.4
Odonnell, J.D.5
Wang, J.6
-
43
-
-
34247614521
-
HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity
-
Zhang H, Gao P, Fukuda R, Kumar G, Krishnamachary B, Zeller KI et al. (2007). HIF-1 inhibits mitochondrial biogenesis and cellular respiration in VHL-deficient renal cell carcinoma by repression of C-MYC activity. Cancer Cell 11: 407-420.
-
(2007)
Cancer Cell
, vol.11
, pp. 407-420
-
-
Zhang, H.1
Gao, P.2
Fukuda, R.3
Kumar, G.4
Krishnamachary, B.5
Zeller, K.I.6
|