메뉴 건너뛰기




Volumn 81, Issue , 2015, Pages 161-168

Targeted electro-delivery of oligonucleotides for RNA interference: SiRNA and antimiR

Author keywords

Electropermeabilization; Electroporation; LNA; RNAi; SiRNA

Indexed keywords

CELL MEMBRANES; OLIGONUCLEOTIDES; RNA;

EID: 84922325410     PISSN: 0169409X     EISSN: 18728294     Source Type: Journal    
DOI: 10.1016/j.addr.2014.05.002     Document Type: Review
Times cited : (24)

References (107)
  • 1
    • 33751099034 scopus 로고    scopus 로고
    • RNAi therapeutics: a potential new class of pharmaceutical drugs
    • Bumcrot D., Manoharan M., Koteliansky V., Sah D.W. RNAi therapeutics: a potential new class of pharmaceutical drugs. Nat. Chem. Biol. 2006, 2:711-719.
    • (2006) Nat. Chem. Biol. , vol.2 , pp. 711-719
    • Bumcrot, D.1    Manoharan, M.2    Koteliansky, V.3    Sah, D.W.4
  • 2
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A., Xu S., Montgomery M.K., Kostas S.A., Driver S.E., Mello C.C. Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 1998, 391:806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 3
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 4
  • 5
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 6
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of miRNAs and siRNAs
    • Carthew R.W., Sontheimer E.J. Origins and mechanisms of miRNAs and siRNAs. Cell 2009, 136:642-655.
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 7
    • 0035966319 scopus 로고    scopus 로고
    • MicroRNAs: tiny regulators with great potential
    • Ambros V. microRNAs: tiny regulators with great potential. Cell 2001, 107:823-826.
    • (2001) Cell , vol.107 , pp. 823-826
    • Ambros, V.1
  • 9
    • 77954941124 scopus 로고    scopus 로고
    • Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions
    • Long J., Wang Y., Wang W., Chang B.H., Danesh F.R. Identification of microRNA-93 as a novel regulator of vascular endothelial growth factor in hyperglycemic conditions. J. Biol. Chem. 2010, 285:23457-23465.
    • (2010) J. Biol. Chem. , vol.285 , pp. 23457-23465
    • Long, J.1    Wang, Y.2    Wang, W.3    Chang, B.H.4    Danesh, F.R.5
  • 14
    • 58849093262 scopus 로고    scopus 로고
    • Revisiting the principles of microRNA target recognition and mode of action
    • Brodersen P., Voinnet O. Revisiting the principles of microRNA target recognition and mode of action. Nat. Rev. Mol. Cell Biol. 2009, 10:141-148.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 141-148
    • Brodersen, P.1    Voinnet, O.2
  • 15
    • 67149115119 scopus 로고    scopus 로고
    • Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
    • Khan A.A., Betel D., Miller M.L., Sander C., Leslie C.S., Marks D.S. Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nat. Biotechnol. 2009, 27:549-555.
    • (2009) Nat. Biotechnol. , vol.27 , pp. 549-555
    • Khan, A.A.1    Betel, D.2    Miller, M.L.3    Sander, C.4    Leslie, C.S.5    Marks, D.S.6
  • 17
    • 34548316982 scopus 로고    scopus 로고
    • MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells
    • Ebert M.S., Neilson J.R., Sharp P.A. MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat. Methods 2007, 4:721-726.
    • (2007) Nat. Methods , vol.4 , pp. 721-726
    • Ebert, M.S.1    Neilson, J.R.2    Sharp, P.A.3
  • 18
    • 64549109671 scopus 로고    scopus 로고
    • Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells
    • Haraguchi T., Ozaki Y., Iba H. Vectors expressing efficient RNA decoys achieve the long-term suppression of specific microRNA activity in mammalian cells. Nucleic Acids Res. 2009, 37:e43.
    • (2009) Nucleic Acids Res. , vol.37 , pp. e43
    • Haraguchi, T.1    Ozaki, Y.2    Iba, H.3
  • 19
    • 78650726076 scopus 로고    scopus 로고
    • Adenovirus-mediated shRNAs for co-repression of miR-221 and miR-222 expression and function in glioblastoma cells
    • Wang X., Han L., Zhang A., Wang G., Jia Z., Yang Y., Yue X., Pu P., Shen C., Kang C. Adenovirus-mediated shRNAs for co-repression of miR-221 and miR-222 expression and function in glioblastoma cells. Oncol. Rep. 2011, 25:97-105.
    • (2011) Oncol. Rep. , vol.25 , pp. 97-105
    • Wang, X.1    Han, L.2    Zhang, A.3    Wang, G.4    Jia, Z.5    Yang, Y.6    Yue, X.7    Pu, P.8    Shen, C.9    Kang, C.10
  • 20
    • 79251469386 scopus 로고    scopus 로고
    • Vigilance and validation: keys to success in RNAi screening
    • Sigoillot F.D., King R.W. Vigilance and validation: keys to success in RNAi screening. ACS Chem. Biol. 2011, 6:47-60.
    • (2011) ACS Chem. Biol. , vol.6 , pp. 47-60
    • Sigoillot, F.D.1    King, R.W.2
  • 21
    • 84883249501 scopus 로고    scopus 로고
    • Canonical and non-canonical barriers facing antimiR cancer therapeutics
    • Cheng C.J., Saltzman W.M., Slack F.J. Canonical and non-canonical barriers facing antimiR cancer therapeutics. Curr. Med. Chem. 2013, 20:3582-3593.
    • (2013) Curr. Med. Chem. , vol.20 , pp. 3582-3593
    • Cheng, C.J.1    Saltzman, W.M.2    Slack, F.J.3
  • 22
    • 83255194160 scopus 로고    scopus 로고
    • Chemical modification and design of anti-miRNA oligonucleotides
    • Lennox K.A., Behlke M.A. Chemical modification and design of anti-miRNA oligonucleotides. Gene Ther. 2011, 18:1111-1120.
    • (2011) Gene Ther. , vol.18 , pp. 1111-1120
    • Lennox, K.A.1    Behlke, M.A.2
  • 23
    • 36849094017 scopus 로고    scopus 로고
    • Chemical modification: the key to clinical application of RNA interference?
    • Corey D.R. Chemical modification: the key to clinical application of RNA interference?. J. Clin. Invest. 2007, 117:3615-3622.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3615-3622
    • Corey, D.R.1
  • 27
    • 36849035783 scopus 로고    scopus 로고
    • Perspectives on chemistry and therapeutic applications of locked nucleic acid (LNA)
    • Kaur H., Babu B.R., Maiti S. Perspectives on chemistry and therapeutic applications of locked nucleic acid (LNA). Chem. Rev. 2007, 107:4672-4697.
    • (2007) Chem. Rev. , vol.107 , pp. 4672-4697
    • Kaur, H.1    Babu, B.R.2    Maiti, S.3
  • 28
    • 0036606669 scopus 로고    scopus 로고
    • Design and characterization of decoy oligonucleotides containing locked nucleic acids
    • Crinelli R., Bianchi M., Gentilini L., Magnani M. Design and characterization of decoy oligonucleotides containing locked nucleic acids. Nucleic Acids Res. 2002, 30:2435-2443.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 2435-2443
    • Crinelli, R.1    Bianchi, M.2    Gentilini, L.3    Magnani, M.4
  • 32
    • 77957361864 scopus 로고    scopus 로고
    • Targeting microRNAs in cancer: rationale, strategies and challenges
    • Garzon R., Marcucci G., Croce C.M. Targeting microRNAs in cancer: rationale, strategies and challenges. Nat. Rev. Drug Discov. 2010, 9:775-789.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 775-789
    • Garzon, R.1    Marcucci, G.2    Croce, C.M.3
  • 34
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • Castanotto D., Rossi J.J. The promises and pitfalls of RNA-interference-based therapeutics. Nature 2009, 457:426-433.
    • (2009) Nature , vol.457 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2
  • 38
    • 0013798651 scopus 로고
    • A quantitative analysis of the voltage-current relationships of fixed charge membranes and the associated property of "punch-through"
    • Coster H.G. A quantitative analysis of the voltage-current relationships of fixed charge membranes and the associated property of "punch-through". Biophys. J. 1965, 5:669-686.
    • (1965) Biophys. J. , vol.5 , pp. 669-686
    • Coster, H.G.1
  • 39
    • 23144463785 scopus 로고    scopus 로고
    • Mechanisms of cell membrane electropermeabilization: a mini-review of our present (lack of ?) knowledge
    • Teissie J., Golzio M., Rols M.P. Mechanisms of cell membrane electropermeabilization: a mini-review of our present (lack of ?) knowledge. Biochim. Biophys. Acta 2005, 1724:270-280.
    • (2005) Biochim. Biophys. Acta , vol.1724 , pp. 270-280
    • Teissie, J.1    Golzio, M.2    Rols, M.P.3
  • 40
    • 4644371368 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: electroporation and other physical methods
    • Wells D.J. Gene therapy progress and prospects: electroporation and other physical methods. Gene Ther. 2004, 11:1363-1369.
    • (2004) Gene Ther. , vol.11 , pp. 1363-1369
    • Wells, D.J.1
  • 41
    • 33750626735 scopus 로고    scopus 로고
    • In vivo electroporation for gene therapy
    • Heller L.C., Heller R. In vivo electroporation for gene therapy. Hum. Gene Ther. 2006, 17:890-897.
    • (2006) Hum. Gene Ther. , vol.17 , pp. 890-897
    • Heller, L.C.1    Heller, R.2
  • 42
    • 70349852417 scopus 로고    scopus 로고
    • Electric pulses used in electrochemotherapy and electrogene therapy do not significantly change the expression profile of genes involved in the development of cancer in malignant melanoma cells
    • Mlakar V., Todorovic V., Cemazar M., Glavac D., Sersa G. Electric pulses used in electrochemotherapy and electrogene therapy do not significantly change the expression profile of genes involved in the development of cancer in malignant melanoma cells. BMC Cancer 2009, 9:299.
    • (2009) BMC Cancer , vol.9 , pp. 299
    • Mlakar, V.1    Todorovic, V.2    Cemazar, M.3    Glavac, D.4    Sersa, G.5
  • 43
    • 0141502361 scopus 로고    scopus 로고
    • Electrochemotherapy: results of cancer treatment using enhanced delivery of bleomycin by electroporation
    • Gothelf A., Mir L.M., Gehl J. Electrochemotherapy: results of cancer treatment using enhanced delivery of bleomycin by electroporation. Cancer Treat. Rev. 2003, 29:371-387.
    • (2003) Cancer Treat. Rev. , vol.29 , pp. 371-387
    • Gothelf, A.1    Mir, L.M.2    Gehl, J.3
  • 46
    • 63949088560 scopus 로고    scopus 로고
    • Electroporation for the delivery of DNA-based vaccines and immunotherapeutics: current clinical developments
    • Bodles-Brakhop A.M., Heller R., Draghia-Akli R. Electroporation for the delivery of DNA-based vaccines and immunotherapeutics: current clinical developments. Mol. Ther. 2009, 17:585-592.
    • (2009) Mol. Ther. , vol.17 , pp. 585-592
    • Bodles-Brakhop, A.M.1    Heller, R.2    Draghia-Akli, R.3
  • 47
    • 0036924811 scopus 로고    scopus 로고
    • Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design
    • Braasch D.A., Liu Y., Corey D.R. Antisense inhibition of gene expression in cells by oligonucleotides incorporating locked nucleic acids: effect of mRNA target sequence and chimera design. Nucleic Acids Res. 2002, 30:5160-5167.
    • (2002) Nucleic Acids Res. , vol.30 , pp. 5160-5167
    • Braasch, D.A.1    Liu, Y.2    Corey, D.R.3
  • 48
    • 35148900227 scopus 로고    scopus 로고
    • MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas
    • Corsten M.F., Miranda R., Kasmieh R., Krichevsky A.M., Weissleder R., Shah K. MicroRNA-21 knockdown disrupts glioma growth in vivo and displays synergistic cytotoxicity with neural precursor cell delivered S-TRAIL in human gliomas. Cancer Res. 2007, 67:8994-9000.
    • (2007) Cancer Res. , vol.67 , pp. 8994-9000
    • Corsten, M.F.1    Miranda, R.2    Kasmieh, R.3    Krichevsky, A.M.4    Weissleder, R.5    Shah, K.6
  • 49
    • 0032522132 scopus 로고    scopus 로고
    • Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus
    • Marcusson E.G., Bhat B., Manoharan M., Bennett C.F., Dean N.M. Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus. Nucleic Acids Res. 1998, 26:2016-2023.
    • (1998) Nucleic Acids Res. , vol.26 , pp. 2016-2023
    • Marcusson, E.G.1    Bhat, B.2    Manoharan, M.3    Bennett, C.F.4    Dean, N.M.5
  • 50
    • 79953767743 scopus 로고    scopus 로고
    • Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection
    • Zhang Y., Qu Z., Kim S., Shi V., Liao B., Kraft P., Bandaru R., Wu Y., Greenberger L.M., Horak I.D. Down-modulation of cancer targets using locked nucleic acid (LNA)-based antisense oligonucleotides without transfection. Gene Ther. 2011, 18:326-333.
    • (2011) Gene Ther. , vol.18 , pp. 326-333
    • Zhang, Y.1    Qu, Z.2    Kim, S.3    Shi, V.4    Liao, B.5    Kraft, P.6    Bandaru, R.7    Wu, Y.8    Greenberger, L.M.9    Horak, I.D.10
  • 51
    • 0027958072 scopus 로고
    • Control by pulse parameters of electric field mediated gene transfer in mammalian cells
    • Wolf H., Rols M.P., Neumann E., Teissié J. Control by pulse parameters of electric field mediated gene transfer in mammalian cells. Biophys. J. 1994, 66:524-531.
    • (1994) Biophys. J. , vol.66 , pp. 524-531
    • Wolf, H.1    Rols, M.P.2    Neumann, E.3    Teissié, J.4
  • 52
    • 0037022335 scopus 로고    scopus 로고
    • Direct visualization at the single-cell level of electrically mediated gene delivery
    • Golzio M., Teissie J., Rols M.P. Direct visualization at the single-cell level of electrically mediated gene delivery. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:1292-1297.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 1292-1297
    • Golzio, M.1    Teissie, J.2    Rols, M.P.3
  • 53
    • 63949083280 scopus 로고    scopus 로고
    • What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues
    • Escoffre J.M., Portet T., Wasungu L., Teissie J., Dean D., Rols M.P. What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues. Mol. Biotechnol. 2009, 41:286-295.
    • (2009) Mol. Biotechnol. , vol.41 , pp. 286-295
    • Escoffre, J.M.1    Portet, T.2    Wasungu, L.3    Teissie, J.4    Dean, D.5    Rols, M.P.6
  • 54
    • 55549136423 scopus 로고    scopus 로고
    • Kinetics of transmembrane transport of small molecules into electropermeabilized cells
    • Pucihar G., Kotnik T., Miklavcic D., Teissié J. Kinetics of transmembrane transport of small molecules into electropermeabilized cells. Biophys. J. 2008, 95:2837-2848.
    • (2008) Biophys. J. , vol.95 , pp. 2837-2848
    • Pucihar, G.1    Kotnik, T.2    Miklavcic, D.3    Teissié, J.4
  • 55
    • 0028957397 scopus 로고
    • Long-lived macropinocytosis takes place in electropermeabilized mammalian cells
    • Rols M.P., Femenia P., Teissie J. Long-lived macropinocytosis takes place in electropermeabilized mammalian cells. Biochem. Biophys. Res. Commun. 1995, 208:26-35.
    • (1995) Biochem. Biophys. Res. Commun. , vol.208 , pp. 26-35
    • Rols, M.P.1    Femenia, P.2    Teissie, J.3
  • 56
    • 0029441955 scopus 로고
    • The introduction of proteins into mammalian cells by electroporation
    • Morgan W.F., Day J.P. The introduction of proteins into mammalian cells by electroporation. Methods Mol. Biol. 1995, 48:63-71.
    • (1995) Methods Mol. Biol. , vol.48 , pp. 63-71
    • Morgan, W.F.1    Day, J.P.2
  • 57
    • 0347928860 scopus 로고    scopus 로고
    • Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells
    • Weil D., Garçon L., Harper M., Duménil D., Dautry F., Kress M. Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells. Biotechniques 2002, 33:1244-1248.
    • (2002) Biotechniques , vol.33 , pp. 1244-1248
    • Weil, D.1    Garçon, L.2    Harper, M.3    Duménil, D.4    Dautry, F.5    Kress, M.6
  • 62
    • 84865644203 scopus 로고    scopus 로고
    • Transport of siRNA through lipid membranes driven by nanosecond electric pulses: an experimental and computational study
    • Breton M., Delemotte L., Silve A., Mir L.M., Tarek M. Transport of siRNA through lipid membranes driven by nanosecond electric pulses: an experimental and computational study. J. Am. Chem. Soc. 2012, 134:13938-13941.
    • (2012) J. Am. Chem. Soc. , vol.134 , pp. 13938-13941
    • Breton, M.1    Delemotte, L.2    Silve, A.3    Mir, L.M.4    Tarek, M.5
  • 65
    • 0020339802 scopus 로고
    • Gene transfer into mouse lyoma cells by electroporation in high electric fields
    • Neumann E., Shaefer-Ridder M., Wang Y., Hofschneider P.H. Gene transfer into mouse lyoma cells by electroporation in high electric fields. EMBO J. 1982, 1:841-845.
    • (1982) EMBO J. , vol.1 , pp. 841-845
    • Neumann, E.1    Shaefer-Ridder, M.2    Wang, Y.3    Hofschneider, P.H.4
  • 66
    • 84864074138 scopus 로고    scopus 로고
    • A stochastic model for DNA translocation through an electropore
    • Yu M., Tan W., Lin H. A stochastic model for DNA translocation through an electropore. BBA Biomembr. 2012, 1818:2494-2501.
    • (2012) BBA Biomembr. , vol.1818 , pp. 2494-2501
    • Yu, M.1    Tan, W.2    Lin, H.3
  • 67
    • 0033594942 scopus 로고    scopus 로고
    • Passive entry of a DNA molecule into a small pore
    • De Gennes P.G. Passive entry of a DNA molecule into a small pore. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:7262-7264.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , pp. 7262-7264
    • De Gennes, P.G.1
  • 68
    • 84872067366 scopus 로고    scopus 로고
    • Statistics of DNA capture by a solid-state nanopore
    • Mihovilovic M., Hagerty N., Stein D. Statistics of DNA capture by a solid-state nanopore. Phys. Rev. Lett. 2013, 110:028102.
    • (2013) Phys. Rev. Lett. , vol.110 , pp. 028102
    • Mihovilovic, M.1    Hagerty, N.2    Stein, D.3
  • 69
    • 2142763965 scopus 로고    scopus 로고
    • Model of creation and evolution of stables electropores for DNA delivery
    • Smith K.C., Neu J.C., Krassowska W. Model of creation and evolution of stables electropores for DNA delivery. Biophys. J. 2004, 86:2813-2826.
    • (2004) Biophys. J. , vol.86 , pp. 2813-2826
    • Smith, K.C.1    Neu, J.C.2    Krassowska, W.3
  • 70
    • 33846441667 scopus 로고    scopus 로고
    • Modeling electroporation in a single cell
    • Krassowska W., Filev P.D. Modeling electroporation in a single cell. Biophys. J. 2007, 92:404-417.
    • (2007) Biophys. J. , vol.92 , pp. 404-417
    • Krassowska, W.1    Filev, P.D.2
  • 72
    • 0030854207 scopus 로고    scopus 로고
    • Sphingosine-mediated electroporative DNA transfer through lipid bilayers
    • Hristova N.I., Tsoneva I., Neumann E. Sphingosine-mediated electroporative DNA transfer through lipid bilayers. FEBS Lett. 1997, 415:81-86.
    • (1997) FEBS Lett. , vol.415 , pp. 81-86
    • Hristova, N.I.1    Tsoneva, I.2    Neumann, E.3
  • 73
    • 0028097173 scopus 로고
    • Dip patch clamp currents suggest electrodiffusive transport of the polyelectrolyte DNA through lipid bilayers
    • Spassova M., Tsoneva I., Petrov A.G., Petkova J.I., Neumann E. Dip patch clamp currents suggest electrodiffusive transport of the polyelectrolyte DNA through lipid bilayers. Biophys. Chem. 1994, 52:267-274.
    • (1994) Biophys. Chem. , vol.52 , pp. 267-274
    • Spassova, M.1    Tsoneva, I.2    Petrov, A.G.3    Petkova, J.I.4    Neumann, E.5
  • 75
    • 13544265637 scopus 로고    scopus 로고
    • Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery
    • Golzio M., Mazzolini L., Moller P., Rols M.P., Teissie J. Inhibition of gene expression in mice muscle by in vivo electrically mediated siRNA delivery. Gene Ther. 2005, 12:246-251.
    • (2005) Gene Ther. , vol.12 , pp. 246-251
    • Golzio, M.1    Mazzolini, L.2    Moller, P.3    Rols, M.P.4    Teissie, J.5
  • 76
    • 0347089037 scopus 로고    scopus 로고
    • Electroporation and RNA interference in the rodent retina in vivo and in vitro
    • Matsuda T., Cepko C.L. Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proc. Natl. Acad. Sci. U. S. A. 2004, 101:16-22.
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 16-22
    • Matsuda, T.1    Cepko, C.L.2
  • 79
    • 15044354554 scopus 로고    scopus 로고
    • RNAi-induced gene silencing by local electroporation in targeting brain region
    • Akaneya Y., Jiang B., Tsumoto T. RNAi-induced gene silencing by local electroporation in targeting brain region. J. Neurophysiol. 2005, 93:594-602.
    • (2005) J. Neurophysiol. , vol.93 , pp. 594-602
    • Akaneya, Y.1    Jiang, B.2    Tsumoto, T.3
  • 81
    • 0036727416 scopus 로고    scopus 로고
    • Efficient delivery of siRNA for inhibition of gene expression in postnatal mice
    • Lewis D.L., Hagstrom J.E., Loomis A.G., Wolff J.A., Herweijer H. Efficient delivery of siRNA for inhibition of gene expression in postnatal mice. Nat. Genet. 2002, 32:107-108.
    • (2002) Nat. Genet. , vol.32 , pp. 107-108
    • Lewis, D.L.1    Hagstrom, J.E.2    Loomis, A.G.3    Wolff, J.A.4    Herweijer, H.5
  • 83
    • 74049124186 scopus 로고    scopus 로고
    • Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
    • Jackson A.L., Linsley P.S. Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application. Nat. Rev. Drug Discov. 2010, 9:57-67.
    • (2010) Nat. Rev. Drug Discov. , vol.9 , pp. 57-67
    • Jackson, A.L.1    Linsley, P.S.2
  • 87
    • 76649088031 scopus 로고    scopus 로고
    • MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling
    • Zhao C., Sun G., Li S., Lang M.F., Yang S., Li W., Shi Y. MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. Proc. Natl. Acad. Sci. U. S. A. 2010, 107:1876-1881.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 1876-1881
    • Zhao, C.1    Sun, G.2    Li, S.3    Lang, M.F.4    Yang, S.5    Li, W.6    Shi, Y.7
  • 88
    • 84864571647 scopus 로고    scopus 로고
    • Transcription factor FoxO1, the dominant mediator of muscle wasting in chronic kidney disease, is inhibited by microRNA-486
    • Xu J., Li R., Workeneh B., Dong Y., Wang X., Hu Z. Transcription factor FoxO1, the dominant mediator of muscle wasting in chronic kidney disease, is inhibited by microRNA-486. Kidney Int. 2012, 82:401-411.
    • (2012) Kidney Int. , vol.82 , pp. 401-411
    • Xu, J.1    Li, R.2    Workeneh, B.3    Dong, Y.4    Wang, X.5    Hu, Z.6
  • 89
    • 84870909757 scopus 로고    scopus 로고
    • Antitumor effectiveness of electrochemotherapy: a systematic review and meta-analysis
    • Mali B., Jarm T., Snoj M., Sersa G., Miklavcic D. Antitumor effectiveness of electrochemotherapy: a systematic review and meta-analysis. Eur. J. Surg. Oncol. 2013, 39:4-16.
    • (2013) Eur. J. Surg. Oncol. , vol.39 , pp. 4-16
    • Mali, B.1    Jarm, T.2    Snoj, M.3    Sersa, G.4    Miklavcic, D.5
  • 91
    • 17444388549 scopus 로고    scopus 로고
    • Effective treatment of perianal tumors in dogs with electrochemotherapy
    • Tozon N., Kodre V., Sersa G., Cemazar M. Effective treatment of perianal tumors in dogs with electrochemotherapy. Anticancer Res. 2005, 25:839-845.
    • (2005) Anticancer Res. , vol.25 , pp. 839-845
    • Tozon, N.1    Kodre, V.2    Sersa, G.3    Cemazar, M.4
  • 92
    • 63049097244 scopus 로고    scopus 로고
    • Electrochemotherapy compared to surgery for treatment of canine mast cell tumors
    • Kodre V., Cemazar M., Pecar J., Sersa G., Cor A., Tozon N. Electrochemotherapy compared to surgery for treatment of canine mast cell tumors. In Vivo 2009, 23:55-62.
    • (2009) In Vivo , vol.23 , pp. 55-62
    • Kodre, V.1    Cemazar, M.2    Pecar, J.3    Sersa, G.4    Cor, A.5    Tozon, N.6
  • 93
    • 0036150087 scopus 로고    scopus 로고
    • Electrochemotherapy of horses. A preliminary clinical report
    • Rols M.P., Tamzali Y., Teissie J. Electrochemotherapy of horses. A preliminary clinical report. Bioelectrochemistry 2002, 55:101-105.
    • (2002) Bioelectrochemistry , vol.55 , pp. 101-105
    • Rols, M.P.1    Tamzali, Y.2    Teissie, J.3
  • 98
  • 99
    • 60649096446 scopus 로고    scopus 로고
    • Non-invasive contact electrodes for in vivo localized cutaneous electropulsation and associated drug and nucleic acid delivery
    • Mazeres S., Sel D., Golzio M., Pucihar G., Tamzali Y., Miklavcic D., Teissie J. Non-invasive contact electrodes for in vivo localized cutaneous electropulsation and associated drug and nucleic acid delivery. J. Control. Release 2009, 134:125-131.
    • (2009) J. Control. Release , vol.134 , pp. 125-131
    • Mazeres, S.1    Sel, D.2    Golzio, M.3    Pucihar, G.4    Tamzali, Y.5    Miklavcic, D.6    Teissie, J.7
  • 101
    • 40349100260 scopus 로고    scopus 로고
    • MicroRNAs and cancer
    • Dalmay T. MicroRNAs and cancer. J. Intern. Med. 2008, 263:366-375.
    • (2008) J. Intern. Med. , vol.263 , pp. 366-375
    • Dalmay, T.1
  • 104
    • 84878601356 scopus 로고    scopus 로고
    • Liposome delivery of microRNA-145 to mesenchymal stem cells leads to immunological off-target effects mediated by RIG-I
    • Karlsen T.A., Brinchmann J.E. Liposome delivery of microRNA-145 to mesenchymal stem cells leads to immunological off-target effects mediated by RIG-I. Mol. Ther. 2013, 21:1169-1181.
    • (2013) Mol. Ther. , vol.21 , pp. 1169-1181
    • Karlsen, T.A.1    Brinchmann, J.E.2
  • 107
    • 84867829784 scopus 로고    scopus 로고
    • Intravital microscopy at the single vessel level brings new insights of vascular modification mechanisms induced by electropermeabilization
    • Bellard E., Markelc B., Pelofy S., Le Guerroué F., Sersa G., Teissié J., Cemazar M., Golzio M. Intravital microscopy at the single vessel level brings new insights of vascular modification mechanisms induced by electropermeabilization. J. Control. Release 2012, 163:396-403.
    • (2012) J. Control. Release , vol.163 , pp. 396-403
    • Bellard, E.1    Markelc, B.2    Pelofy, S.3    Le Guerroué, F.4    Sersa, G.5    Teissié, J.6    Cemazar, M.7    Golzio, M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.