Aging and chronic DNA damage response activate a regulatory pathway involving miR-29 and p53

EMBO Journal

Volumn 30, Issue 11, 2011, Pages 2219-2232

  Ugalde, Alejandro P ^a   Ramsay, Andrew J ^a   De La Rosa, Jorge ^b   Varela, Ignacio ^a   Marĩo, Guillermo ^a   Cadĩanos, Juan ^b   Lu, Jun ^c   Freije, José M P ^a   López Otín, Carlos ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^b Instituto de Medicina Oncologica y Molecular de Asturias   (Spain)

^c YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cancer; microRNA; phosphatase; progeria; tumour suppressor

Indexed keywords

ADAMTS1 PROTEIN; DOXORUBICIN; LUCIFERASE; MICRORNA; PHOSPHATASE; PROTEIN; PROTEIN P53; PROTEIN PPM1D; UNCLASSIFIED DRUG;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; DNA DAMAGE; FIBROBLAST; GENETIC TRANSFECTION; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROGERIA; PROTEIN PHOSPHORYLATION; SENESCENCE; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TREATMENT OUTCOME; UPREGULATION;

AGING; ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DNA DAMAGE; FIBROBLASTS; GENE EXPRESSION REGULATION; MEMBRANE PROTEINS; METALLOENDOPEPTIDASES; MICE; MICE, KNOCKOUT; MICRORNAS; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEIN PHOSPHATASES; SEQUENCE ANALYSIS, DNA; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; MURINAE; MUS;

EID: 79957900395     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2011.124     Document Type: Article

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