-
1
-
-
52549087785
-
Cancer stem cells in solid tumours: Accumulating evidence and unresolved questions
-
Visvader, J.E. & Lindeman, G.J. Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat. Rev. Cancer 8, 755-768 (2008).
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 755-768
-
-
Visvader, J.E.1
Lindeman, G.J.2
-
2
-
-
22144461002
-
MiRNAs, cancer, and stem cell division
-
DOI 10.1016/j.cell.2005.06.036, PII S0092867405006550
-
Croce, C.M. & Calin, G.A. miRNAs, cancer, and stem cell division. Cell 122, 6-7 (2005). (Pubitemid 40977933)
-
(2005)
Cell
, vol.122
, Issue.1
, pp. 6-7
-
-
Croce, C.M.1
Calin, G.A.2
-
3
-
-
76249119007
-
Opposing microRNA families regulate self-renewal in mouse embryonic stem cells
-
Melton, C., Judson, R.L. & Blelloch, R. Opposing microRNA families regulate self-renewal in mouse embryonic stem cells. Nature 463, 621-626 (2010).
-
(2010)
Nature
, vol.463
, pp. 621-626
-
-
Melton, C.1
Judson, R.L.2
Blelloch, R.3
-
4
-
-
36849078711
-
Let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
-
DOI 10.1016/j.cell.2007.10.054, PII S0092867407014171
-
Yu, F. et al. let-7 regulates self-renewal and tumorigenicity of breast cancer cells. Cell 131, 1109-1123 (2007). (Pubitemid 350235025)
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1109-1123
-
-
Yu, F.1
Yao, H.2
Zhu, P.3
Zhang, X.4
Pan, Q.5
Gong, C.6
Huang, Y.7
Hu, X.8
Su, F.9
Lieberman, J.10
Song, E.11
-
5
-
-
68049114782
-
Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells
-
Shimono, Y. et al. Downregulation of miRNA-200c links breast cancer stem cells with normal stem cells. Cell 138, 592-603 (2009).
-
(2009)
Cell
, vol.138
, pp. 592-603
-
-
Shimono, Y.1
-
6
-
-
33645294070
-
Oncomirs-microRNAs with a role in cancer
-
Esquela-Kerscher, A. & Slack, F.J. Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer 6, 259-269 (2006).
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 259-269
-
-
Esquela-Kerscher, A.1
Slack, F.J.2
-
7
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
DOI 10.1073/pnas.0530291100
-
Al-Hajj, M., Wicha, M.S., Benito-Hernandez, A., Morrison, S.J. & Clarke, M.F. Prospective identifcation of tumorigenic breast cancer cells. Proc. Natl. Acad. Sci. USA 100, 3983-3988 (2003). (Pubitemid 36418143)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.7
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
8
-
-
33847052127
-
Identifcation of pancreatic cancer stem cells
-
Li, C. et al. Identifcation of pancreatic cancer stem cells. Cancer Res. 67, 1030-1037 (2007).
-
(2007)
Cancer Res.
, vol.67
, pp. 1030-1037
-
-
Li, C.1
-
9
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
DOI 10.1073/pnas.0610117104
-
Prince, M.E. et al. Identifcation of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc. Natl. Acad. Sci. USA 104, 973-978 (2007). (Pubitemid 46154721)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.3
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
Wolf, G.T.4
Kaplan, M.J.5
Dalerba, P.6
Weissman, I.L.7
Clarke, M.F.8
Ailles, L.E.9
-
10
-
-
34547193404
-
Phenotypic characterization of human colorectal cancer stem cells
-
DOI 10.1073/pnas.0703478104
-
Dalerba, P. et al. Phenotypic characterization of human colorectal cancer stem cells. Proc. Natl. Acad. Sci. USA 104, 10158-10163 (2007). (Pubitemid 47175279)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.24
, pp. 10158-10163
-
-
Dalerba, P.1
Dylla, S.J.2
Park, I.-K.3
Liu, R.4
Wang, X.5
Cho, R.W.6
Hoey, T.7
Gurney, A.8
Huang, E.H.9
Simeone, D.M.10
Shelton, A.A.11
Parmiani, G.12
Castelli, C.13
Clarke, M.F.14
-
11
-
-
58149269566
-
CD44 is of functional importance for colorectal cancer stem cells
-
Du, L. et al. CD44 is of functional importance for colorectal cancer stem cells. Clin. Cancer Res. 14, 6751-6760 (2008).
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 6751-6760
-
-
Du, L.1
-
12
-
-
45549109525
-
Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis
-
Zeilstra, J. et al. Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis. Cancer Res. 68, 3655-3661 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 3655-3661
-
-
Zeilstra, J.1
-
13
-
-
38549139140
-
+ Cancer Stem Cells in Human Liver Cancer
-
DOI 10.1016/j.ccr.2008.01.013, PII S1535610808000093
-
Yang, Z.F. et al. Signifcance of CD90+ cancer stem cells in human liver cancer. Cancer Cell 13, 153-166 (2008). (Pubitemid 351163165)
-
(2008)
Cancer Cell
, vol.13
, Issue.2
, pp. 153-166
-
-
Yang, Z.F.1
Ho, D.W.2
Ng, M.N.3
Lau, C.K.4
Yu, W.C.5
Ngai, P.6
Chu, P.W.K.7
Lam, C.T.8
Poon, R.T.P.9
Fan, S.T.10
-
14
-
-
66149175569
-
Identifcation of gastric cancer stem cells using the cell surface marker CD44
-
Takaishi, S. et al. Identifcation of gastric cancer stem cells using the cell surface marker CD44. Stem Cells 27, 1006-1020 (2009).
-
(2009)
Stem Cells
, vol.27
, pp. 1006-1020
-
-
Takaishi, S.1
-
15
-
-
69549114870
-
Identifcation, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
-
Chan, K.S. et al. Identifcation, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc. Natl. Acad. Sci. USA 106, 14016-14021 (2009).
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 14016-14021
-
-
Chan, K.S.1
-
16
-
-
49249091523
-
Identifcation and characterization of ovarian cancer-initiating cells from primary human tumors
-
Zhang, S. et al. Identifcation and characterization of ovarian cancer-initiating cells from primary human tumors. Cancer Res. 68, 4311-4320 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 4311-4320
-
-
Zhang, S.1
-
17
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
DOI 10.1158/0008-5472.CAN-05-2018
-
Collins, A.T., Berry, P.A., Hyde, C., Stower, M.J. & Maitland, N.J. Prospective identifcation of tumorigenic prostate cancer stem cells. Cancer Res. 65, 10946-10951 (2005). (Pubitemid 41713363)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10946-10951
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
18
-
-
33645026803
-
+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells
-
+ prostate cancer cells from xenograft human tumors are enriched in tumorigenic and metastatic progenitor cells. Oncogene 25, 1696-1708 (2006).
-
(2006)
Oncogene
, vol.25
, pp. 1696-1708
-
-
Patrawala, L.1
-
20
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
DOI 10.1038/nature05939, PII NATURE05939
-
He, L. et al. A microRNA component of the p53 tumour suppressor network. Nature 447, 1130-1134 (2007). (Pubitemid 47014436)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
Xue, W.7
Zender, L.8
Magnus, J.9
Ridzon, D.10
Jackson, A.L.11
Linsley, P.S.12
Chen, C.13
Lowe, S.W.14
Cleary, M.A.15
Hannon, G.J.16
-
21
-
-
34249822779
-
Transcriptional Activation of miR-34a Contributes to p53-Mediated Apoptosis
-
DOI 10.1016/j.molcel.2007.05.017, PII S1097276507003188
-
Raver-Shapira, N. et al. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. Mol. Cell 26, 731-743 (2007). (Pubitemid 46856247)
-
(2007)
Molecular Cell
, vol.26
, Issue.5
, pp. 731-743
-
-
Raver-Shapira, N.1
Marciano, E.2
Meiri, E.3
Spector, Y.4
Rosenfeld, N.5
Moskovits, N.6
Bentwich, Z.7
Oren, M.8
-
22
-
-
34249817549
-
Transactivation of miR-34a by p53 broadly infuences gene expression and promotes apoptosis
-
Chang, T.C. et al. Transactivation of miR-34a by p53 broadly infuences gene expression and promotes apoptosis. Mol. Cell 26, 745-752 (2007).
-
(2007)
Mol. Cell
, vol.26
, pp. 745-752
-
-
Chang, T.C.1
-
23
-
-
34547458550
-
P53-Mediated Activation of miRNA34 Candidate Tumor-Suppressor Genes
-
DOI 10.1016/j.cub.2007.06.068, PII S0960982207016387
-
Bommer, G.T. et al. p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Curr. Biol. 17, 1298-1307 (2007). (Pubitemid 47176893)
-
(2007)
Current Biology
, vol.17
, Issue.15
, pp. 1298-1307
-
-
Bommer, G.T.1
Gerin, I.2
Feng, Y.3
Kaczorowski, A.J.4
Kuick, R.5
Love, R.E.6
Zhai, Y.7
Giordano, T.J.8
Qin, Z.S.9
Moore, B.B.10
MacDougald, O.A.11
Cho, K.R.12
Fearon, E.R.13
-
24
-
-
34250868124
-
1-arrest
-
Tarasov, V. et al. Differential regulation of microRNAs by p53 revealed by massively parallel sequencing: miR-34a is a p53 target that induces apoptosis and G1-arrest. Cell Cycle 6, 1586-1593 (2007). (Pubitemid 47327945)
-
(2007)
Cell Cycle
, vol.6
, Issue.13
, pp. 1586-1593
-
-
Tarasov, V.1
Jung, P.2
Verdoodt, B.3
Lodygin, D.4
Epanchintsev, A.5
Menssen, A.6
Meister, G.7
Hermeking, H.8
-
25
-
-
34548012848
-
The let-7 microRNA represses cell proliferation pathways in human cells
-
DOI 10.1158/0008-5472.CAN-07-1083
-
Johnson, C.D. et al. The let-7 microRNA represses cell proliferation pathways in human cells. Cancer Res. 67, 7713-7722 (2007). (Pubitemid 47281364)
-
(2007)
Cancer Research
, vol.67
, Issue.16
, pp. 7713-7722
-
-
Johnson, C.D.1
Esquela-Kerscher, A.2
Stefani, G.3
Byrom, M.4
Kelnar, K.5
Ovcharenko, D.6
Wilson, M.7
Wang, X.8
Shelton, J.9
Shingara, J.10
Chin, L.11
Brown, D.12
Slack, F.J.13
-
26
-
-
77955022405
-
Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34
-
Wiggins, J.F. et al. Development of a lung cancer therapeutic based on the tumor suppressor microRNA-34. Cancer Res. 70, 5923-5930 (2010).
-
(2010)
Cancer Res.
, vol.70
, pp. 5923-5930
-
-
Wiggins, J.F.1
-
27
-
-
66149167315
-
Functional evidence that the self-renewal gene NANOG regulates human tumor development
-
Jeter, C.R. et al. Functional evidence that the self-renewal gene NANOG regulates human tumor development. Stem Cells 27, 993-1005 (2009).
-
(2009)
Stem Cells
, vol.27
, pp. 993-1005
-
-
Jeter, C.R.1
-
28
-
-
22244433866
-
- cancer cells are similarly tumorigenic
-
DOI 10.1158/0008-5472.CAN-05-0592
-
- cancer cells are similarly tumorigenic. Cancer Res. 65, 6207-6219 (2005). (Pubitemid 40994406)
-
(2005)
Cancer Research
, vol.65
, Issue.14
, pp. 6207-6219
-
-
Patrawala, L.1
Calhoun, T.2
Schneider-Broussard, R.3
Zhou, J.4
Claypool, K.5
Tang, D.G.6
-
29
-
-
55549102666
-
Critical and distinct roles of p16 and telomerase in regulating the proliferative lifespan of normal human prostate epithelial progenitor cells
-
Bhatia, B. et al. Critical and distinct roles of p16 and telomerase in regulating the proliferative lifespan of normal human prostate epithelial progenitor cells. J. Biol. Chem. 283, 27957-27972 (2008).
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27957-27972
-
-
Bhatia, B.1
-
30
-
-
70449707800
-
Methodologies in assaying prostate cancer stem cells
-
Li, H.W. et al. Methodologies in assaying prostate cancer stem cells. Methods Mol. Biol. 568, 85-138 (2009).
-
(2009)
Methods Mol. Biol.
, vol.568
, pp. 85-138
-
-
Li, H.W.1
-
31
-
-
74249123570
-
The miR-34 family in cancer and apoptosis
-
Hermeking, H. The miR-34 family in cancer and apoptosis. Cell Death Differ. 17, 193-199 (2010).
-
(2010)
Cell Death Differ.
, vol.17
, pp. 193-199
-
-
Hermeking, H.1
-
32
-
-
40949088678
-
PC3 human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells
-
DOI 10.1158/0008-5472.CAN-07-5878
-
Li, H., Chen, X., Calhoun-Davis, T., Claypool, K. & Tang, D.G. PC3 Human prostate carcinoma cell holoclones contain self-renewing tumor-initiating cells. Cancer Res. 68, 1820-1825 (2008). (Pubitemid 351416567)
-
(2008)
Cancer Research
, vol.68
, Issue.6
, pp. 1820-1825
-
-
Li, H.1
Chen, X.2
Calhoun-Davis, T.3
Claypool, K.4
Tang, D.G.5
-
33
-
-
0037948854
-
In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells
-
DOI 10.1101/gad.1061803
-
Dontu, G. et al. In vitro propagation and transcriptional profling of human mammary stem/progenitor cells. Genes Dev. 17, 1253-1270 (2003). (Pubitemid 36583168)
-
(2003)
Genes and Development
, vol.17
, Issue.10
, pp. 1253-1270
-
-
Dontu, G.1
Abdallah, W.M.2
Foley, J.M.3
Jackson, K.W.4
Clarke, M.F.5
Kawamura, M.J.6
Wicha, M.S.7
-
34
-
-
51649115553
-
MiR-34a repression of SIRT1 regulates apoptosis
-
Yamakuchi, M., Ferlito, M. & Lowenstein, C.J. miR-34a repression of SIRT1 regulates apoptosis. Proc. Natl. Acad. Sci. USA 105, 13421-13426 (2008).
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 13421-13426
-
-
Yamakuchi, M.1
Ferlito, M.2
Lowenstein, C.J.3
-
35
-
-
70350221952
-
MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes
-
Li, Y. et al. MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res. 69, 7569-7576 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 7569-7576
-
-
Li, Y.1
-
36
-
-
33748587841
-
A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes
-
DOI 10.1016/j.cell.2006.07.031, PII S0092867406010993
-
Miranda, K.C. et al. A pattern-based method for the identifcation of microRNA-target sites and their corresponding RNA/RNA complexes. Cell 126, 1203-1217 (2006). (Pubitemid 44380294)
-
(2006)
Cell
, vol.126
, Issue.6
, pp. 1203-1217
-
-
Miranda, K.C.1
Huynh, T.2
Tay, Y.3
Ang, Y.-S.4
Tam, W.-L.5
Thomson, A.M.6
Lim, B.7
Rigoutsos, I.8
-
37
-
-
46149089421
-
Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression
-
DOI 10.1016/j.cell.2008.06.006, PII S009286740800754X
-
Godar, S. et al. Growth-inhibitory and tumor-suppressive functions of p53 depend on its repression of CD44 expression. Cell 134, 62-73 (2008). (Pubitemid 351905743)
-
(2008)
Cell
, vol.134
, Issue.1
, pp. 62-73
-
-
Godar, S.1
Ince, T.A.2
Bell, G.W.3
Feldser, D.4
Donaher, J.L.5
Bergh, J.6
Liu, A.7
Miu, K.8
Watnick, R.S.9
Reinhardt, F.10
McAllister, S.S.11
Jacks, T.12
Weinberg, R.A.13
-
38
-
-
33749515476
-
Targeting of CD44 eradicates human acute myeloid leukemic stem cells
-
DOI 10.1038/nm1483, PII NM1483
-
Jin, L., Hope, K.J., Zhai, Q., Smadja-Joffe, F. & Dick, J.E. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat. Med. 12, 1167-1174 (2006). (Pubitemid 44527352)
-
(2006)
Nature Medicine
, vol.12
, Issue.10
, pp. 1167-1174
-
-
Jin, L.1
Hope, K.J.2
Zhai, Q.3
Smadja-Joffe, F.4
Dick, J.E.5
-
39
-
-
69949087531
-
MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells
-
Ji, Q. et al. MicroRNA miR-34 inhibits human pancreatic cancer tumor-initiating cells. PLoS ONE 4, e6816 (2009).
-
(2009)
PLoS ONE
, vol.4
-
-
Ji, Q.1
|