RAS is regulated by the let-7 microRNA family

Cell

Volumn 120, Issue 5, 2005, Pages 635-647

  Johnson, Steven M ^a   Grosshans, Helge ^a   Shingara, Jaclyn ^b   Byrom, Mike ^b   Jarvis, Rich ^b   Cheng, Angie ^b   Labourier, Emmanuel ^b   Reinert, Kristy L ^a   Brown, David ^b   Slack, Frank J ^a  

^a YALE UNIVERSITY   (United States)

^b APPLIED BIOSYSTEMS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY RNA; MICRORNA; RAS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE CONTROL; GENE EXPRESSION; GENE LOSS; GENE MUTATION; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; LUNG PARENCHYMA; LUNG TUMOR; MULTIGENE FAMILY; NONHUMAN; ONCOGENE RAS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; REPORTER GENE; STEM CELL;

EUKARYOTA;

EID: 20044395613     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cell.2005.01.014     Document Type: Article

References (56)

1. J.E. Abrahante, A.L. Daul, M. Li, M.L. Volk, J.M. Tennessen, E.A. Miller, and A.E. Rougvie The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs Dev. Cell 4 2003 625 637
2. S.A. Ahrendt, P.A. Decker, E.A. Alawi, Y.R. Zhu Yr, M. Sanchez-Cespedes, S.C. Yang, G.B. Haasler, A. Kajdacsy-Balla, M.J. Demeure, and D. Sidransky Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung Cancer 92 2001 1525 1530
3. V. Ambros Cell cycle-dependent sequencing of cell fate decisions in Caenorhabditis elegans vulva precursor cells Development 126 1999 1947 1956
4. D.P. Bartel MicroRNAs: Genomics, biogenesis, mechanism, and function Cell 116 2004 281 297
5. G.J. Beitel, S.G. Clark, and H.R. Horvitz Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction Nature 348 1990 503 509
6. T. Berset, E.F. Hoier, G. Battu, S. Canevascini, and A. Hajnal Notch inhibition of RAS signaling through MAP kinase phosphatase LIP-1 during C. elegans vulval development Science 291 2001 1055 1058
7. J. Brennecke, D.R. Hipfner, A. Stark, R.B. Russell, and S.M. Cohen bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila Cell 113 2003 25 36
8. G.A. Calin, C.D. Dumitru, M. Shimizu, R. Bichi, S. Zupo, E. Noch, H. Aldler, S. Rattan, M. Keating, and K. Rai Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia Proc. Natl. Acad. Sci. USA 99 2002 15524 15529
9. G.A. Calin, C. Sevignani, C.D. Dumitru, T. Hyslop, E. Noch, S. Yendamuri, M. Shimizu, S. Rattan, F. Bullrich, M. Negrini, and C.M. Croce Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers Proc. Natl. Acad. Sci. USA 101 2004 2999 3004
10. C.J. Ceol, and H.R. Horvitz A new class of C. elegans synMuv genes implicates a Tip60/NuA4-like HAT complex as a negative regulator of Ras signaling Dev. Cell 6 2004 563 576
11. S. Chang, R.J. Johnston Jr., C. Frokjaer-Jensen, S. Lockery, and O. Hobert MicroRNAs act sequentially and asymmetrically to control chemosensory laterality in the nematode Nature 430 2004 785 789
12. C.Z. Chen, L. Li, H.F. Lodish, and D.P. Bartel MicroRNAs modulate hematopoietic lineage differentiation Science 303 2004 83 86
13. J.A. Dent, and M. Han Post-embryonic expression pattern of C. elegans let-60 ras reporter constructs Mech. Dev. 72 1998 179 182
14. D.M. Eisenmann, and S.K. Kim Mechanism of activation of the Caenorhabditis elegans ras homologue let-60 by a novel, temperature-sensitive, gain-of-function mutation Genetics 146 1997 553 565
15. C.E. Gauwerky, K. Huebner, M. Isobe, P.C. Nowell, and C.M. Croce Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia Proc. Natl. Acad. Sci. USA 86 1989 8867 8871
16. H. Grosshans, T. Johnson, K.L. Reinert, M. Gerstein, and F.J. Slack The temporal patterning microRNA let-7 controls several transcription factors during the larval to adult transition in C. elegans Dev. Cell 8 2005 321 330
17. M. Han, R.V. Aroian, and P.W. Sternberg The let-60 locus controls the switch between vulval and nonvulval cell fates in Caenorhabditis elegans Genetics 126 1990 899 913
18. M. Han, and P.W. Sternberg let-60, a gene that specifies cell fates during C. elegans vulval induction, encodes a ras protein Cell 63 1990 921 931
19. N.A. Hopper, J. Lee, and P.W. Sternberg ARK-1 inhibits EGFR signaling in C. elegans Mol. Cell 6 2000 65 75
20. Hutvágner, G., Simard, M.J., Mello, C.C., and Zamore, P.D. (2004). Sequence-specific inhibition of small RNA function. PLoS Biol. 2(4): e98. DOI: 10.1371/journal.pbio.0020098.
21. L. Johnson, K. Mercer, D. Greenbaum, R.T. Bronson, D. Crowley, D.A. Tuveson, and T. Jacks Somatic activation of the K-ras oncogene causes early onset lung cancer in mice Nature 410 2001 1111 1116
22. S.M. Johnson, S.Y. Lin, and F.J. Slack The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter Dev. Biol. 259 2003 364 379
23. R.J. Johnston, and O. Hobert A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans Nature 426 2003 845 849
24. W.S. Katz, R.J. Hill, T.R. Clandinin, and P.W. Sternberg Different levels of the C. elegans growth factor LIN-3 promote distinct vulval precursor fates Cell 82 1995 297 307
25. M. Lagos-Quintana, R. Rauhut, W. Lendeckel, and T. Tuschl Identification of novel genes coding for small expressed RNAs Science 294 2001 853 858
26. M. Lagos-Quintana, R. Rauhut, A. Yalcin, J. Meyer, W. Lendeckel, and T. Tuschl Identification of tissue-specific microRNAs from mouse Curr. Biol. 12 2002 735 739
27. N.C. Lau, L.P. Lim, E.G. Weinstein, and D.P. Bartel An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans Science 294 2001 858 862
28. R.C. Lee, and V. Ambros An extensive class of small RNAs in Caenorhabditis elegans Science 294 2001 862 864
29. R.C. Lee, R.L. Feinbaum, and V. Ambros The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 Cell 75 1993 843 854
30. J. Lee, G.D. Jongeward, and P.W. Sternberg unc-101, a gene required for many aspects of Caenorhabditis elegans development and behavior, encodes a clathrin-associated protein Genes Dev. 8 1994 60 73
31. B.P. Lewis, I.H. Shih, M.W. Jones-Rhoades, D.P. Bartel, and C.B. Burge Prediction of mammalian microRNA targets Cell 115 2003 787 798
32. L.P. Lim, N.C. Lau, E.G. Weinstein, A. Abdelhakim, S. Yekta, M.W. Rhoades, C.B. Burge, and D.P. Bartel The microRNAs of Caenorhabditis elegans Genes Dev. 17 2003 991 1008
33. S.Y. Lin, S.M. Johnson, M. Abraham, M.C. Vella, A. Pasquinelli, C. Gamberi, E. Gottlieb, and F.J. Slack The C. elegans hunchback homolog, hbl-1, controls temporal patterning and is a probable microRNA target Dev. Cell 4 2003 639 650
34. M. Malumbres, and M. Barbacid RAS oncogenes: the first 30 years Nat. Rev. Cancer 3 2003 459 465
35. I.A. McKay, C.J. Marshall, C. Cales, and A. Hall Transformation and stimulation of DNA synthesis in NIH-3T3 cells are a titratable function of normal p21N-ras expression EMBO J. 5 1986 2617 2621
36. M.T. McManus MicroRNAs and cancer Semin. Cancer Biol. 13 2003 253 258
37. G. Meister, M. Landthaler, Y. Dorsett, and T. Tuschl Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing RNA 10 2004 544 550
38. M.Z. Michael, S.M. O'Connor, N.G. van Holst Pellekaan, G.P. Young, and R.J. James Reduced accumulation of specific microRNAs in colorectal neoplasia Mol. Cancer Res. 1 2003 882 891
39. E.G. Moss, R.C. Lee, and V. Ambros The cold shock domain protein LIN-28 controls developmental timing in C. elegans and is regulated by the lin-4 RNA Cell 88 1997 637 646
40. A. Pasquinelli, B. Reinhart, F. Slack, B. Maller, and G. Ruvkun Conservation across animal phylogeny of the sequence and temporal regulation of the 21 nucleotide C. elegans let-7 heterochronic regulatory RNA Nature 408 2000 86 89
41. S. Pulciani, E. Santos, L.K. Long, V. Sorrentino, and M. Barbacid ras gene amplification and malignant transformation Mol. Cell. Biol. 5 1985 2836 2841
42. B. Reinhart, F. Slack, M. Basson, A. Pasquinelli, J. Bettinger, A. Rougvie, R. Horvitz, and G. Ruvkun The 21 nucleotide let-7 RNA regulates C. elegans developmental timing Nature 403 2000 901 906
43. F.J. Slack, M. Basson, Z. Liu, V. Ambros, H.R. Horvitz, and G. Ruvkun The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the lin-29 transcription factor Mol. Cell 5 2000 659 669
44. Stein, L.D., Bao, Z., Blasiar, D., Blumenthal, T., Brent, M.R., Chen, N., Chinwalla, A., Clarke, L., Clee, C., Coghlan, A., et al. (2003). The genome sequence of Caenorhabditis briggsae: a platform for comparative genomics. PLoS Biol. 1(2) e45 DOI: 10.1371/journal.pbio.0000045.
45. P.W. Sternberg Lateral inhibition during vulval induction in Caenorhabditis elegans Nature 335 1988 551 554
46. J.E. Sulston, and H.R. Horvitz Post-embryonic cell lineages of the nematode, Caenorhabditis elegans Dev. Biol. 56 1977 110 156
47. J. Takamizawa, H. Konishi, K. Yanagisawa, S. Tomida, H. Osada, H. Endoh, T. Harano, Y. Yatabe, M. Nagino, and Y. Nimura Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival Cancer Res. 64 2004 3753 3756
48. W. Tam Identification and characterization of human BIC, a gene on chromosome 21 that encodes a noncoding RNA Gene 274 2001 157 167
49. W. Tam, S.H. Hughes, W.S. Hayward, and P. Besmer Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis J. Virol. 76 2002 4275 4286
50. P.B. Tan, M.R. Lackner, and S.K. Kim MAP kinase signaling specificity mediated by the LIN-1 Ets/LIN-31 WH transcription factor complex during C. elegans vulval induction Cell 93 1998 569 580
51. L. Timmons, D.L. Court, and A. Fire Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans Gene 263 2001 103 112
52. M.C. Vella, E.-Y. Choi, S.Y. Lin, K. Reinert, and F.J. Slack The C. elegans microRNA let-7 binds to imperfect let-7 complementary sites from the lin-41 3′UTR Genes Dev. 18 2004 132 137
53. M. Wang, and P.W. Sternberg Pattern formation during C. elegans vulval induction Curr. Top. Dev. Biol. 51 2001 189 220
54. B. Wightman, I. Ha, and G. Ruvkun Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans Cell 75 1993 855 862
55. A.S. Yoo, C. Bais, and I. Greenwald Crosstalk between the EGFR and LIN-12/Notch pathways in C. elegans vulval development Science 303 2004 663 666
56. C.H. Yoon, J. Lee, G.D. Jongeward, and P.W. Sternberg Similarity of sli-1, a regulator of vulval development in C. elegans, to the mammalian proto-oncogene c-cbl Science 269 1995 1102 1105