메뉴 건너뛰기




Volumn 31, Issue 6, 2009, Pages 1110-1115

Hypomethylation and genome instability in the germline of exposed parents and their progeny is associated with altered miRNA expression

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLTRANSFERASE 3A; HELICASE; LYMPHOID SPECIFIC HELICASE; MICRORNA; UNCLASSIFIED DRUG;

EID: 77953947756     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgp300     Document Type: Article
Times cited : (85)

References (58)
  • 1
    • 33744917239 scopus 로고    scopus 로고
    • The offspring of irradiated parents, are they stable? Mutat
    • Barber, R.C. et al. (2006) The offspring of irradiated parents, are they stable? Mutat. Res., 598, 50-60.
    • (2006) Res , vol.598 , pp. 50-60
    • Barber, R.C.1
  • 2
    • 0242574353 scopus 로고    scopus 로고
    • Radiation-induced transgenerational instability
    • Dubrova, Y.E. (2003) Radiation-induced transgenerational instability. Oncogene, 22, 7087-7093.
    • (2003) Oncogene , vol.22 , pp. 7087-7093
    • Dubrova, Y.E.1
  • 3
    • 33749544688 scopus 로고    scopus 로고
    • Radiation induced dynamic mutations and transgenerational effects
    • Niwa, O. (2006) Radiation induced dynamic mutations and transgenerational effects. J. Radiat. Res. (Tokyo), 47 (suppl. B), B25-B30.
    • (2006) J. Radiat. Res. (Tokyo) , vol.47 , Issue.SUPPL. B
    • Niwa, O.1
  • 4
    • 0038640479 scopus 로고    scopus 로고
    • Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects
    • Morgan, W.F. (2003) Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiat. Res., 159, 581-596.
    • (2003) Radiat. Res. , vol.159 , pp. 581-596
    • Morgan, W.F.1
  • 6
    • 42949170867 scopus 로고    scopus 로고
    • Paternal exposure to ethylnitrosourea results in transgenerational genomic instability in mice
    • Dubrova, Y.E. et al. (2008) Paternal exposure to ethylnitrosourea results in transgenerational genomic instability in mice. Environ. Mol. Mutagen., 49, 308-311.
    • (2008) Environ. Mol. Mutagen. , vol.49 , pp. 308-311
    • Dubrova, Y.E.1
  • 7
    • 47849103962 scopus 로고    scopus 로고
    • Transgenerational effects from exposure to environmental toxic substances
    • Nomura, T. (2008) Transgenerational effects from exposure to environmental toxic substances. Mutat. Res., 659, 185-193.
    • (2008) Mutat. Res. , vol.659 , pp. 185-193
    • Nomura, T.1
  • 8
    • 45549102409 scopus 로고    scopus 로고
    • Single-molecule PCR analysis of germ line mutation induction by anticancer drugs in mice
    • Glen, C.D. et al. (2008) Single-molecule PCR analysis of germ line mutation induction by anticancer drugs in mice. Cancer Res., 68, 3630-3636.
    • (2008) Cancer Res , vol.68 , pp. 3630-3636
    • Glen, C.D.1
  • 9
    • 20444452498 scopus 로고    scopus 로고
    • Impact of paternal exposure to chemotherapy on offspring in the rat
    • Hales, B.F. et al. (2005) Impact of paternal exposure to chemotherapy on offspring in the rat. J. Natl Cancer Inst. Monogr., 34, 28-31.
    • (2005) J. Natl Cancer Inst. Monogr. , vol.34 , pp. 28-31
    • Hales, B.F.1
  • 10
    • 0345686425 scopus 로고    scopus 로고
    • Long-term genetic effects of radiation exposure
    • Dubrova, Y.E. (2003) Long-term genetic effects of radiation exposure. Mutat. Res., 544, 433-439.
    • (2003) Mutat. Res. , vol.544 , pp. 433-439
    • Dubrova, Y.E.1
  • 11
    • 0342313475 scopus 로고    scopus 로고
    • Transgenerational mutation by radiation
    • Dubrova, Y.E. et al. (2000) Transgenerational mutation by radiation. Nature, 405, 37.
    • (2000) Nature , vol.405 , pp. 37
    • Dubrova, Y.E.1
  • 12
    • 24044503756 scopus 로고    scopus 로고
    • Gamma irradiation of Type B spermatogonia leads to heritable genomic instability in four generations of mice
    • Baulch, J.E. et al. (2005) Gamma irradiation of Type B spermatogonia leads to heritable genomic instability in four generations of mice. Mutagenesis, 20, 337-43.
    • (2005) Mutagenesis , vol.20 , pp. 337-343
    • Baulch, J.E.1
  • 13
    • 2642531973 scopus 로고    scopus 로고
    • Epigenetics in human disease and prospects for epigenetic therapy
    • Egger, G. et al. (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature, 429, 457-463.
    • (2004) Nature , vol.429 , pp. 457-463
    • Egger, G.1
  • 14
    • 40949093544 scopus 로고    scopus 로고
    • Epigenetics at the epicenter of modern medicine
    • Feinberg, A.P. (2008) Epigenetics at the epicenter of modern medicine. JAMA, 299, 1345-1350.
    • (2008) JAMA , vol.299 , pp. 1345-1350
    • Feinberg, A.P.1
  • 15
    • 0037372003 scopus 로고    scopus 로고
    • Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
    • Jaenisch, R. et al. (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet., 33 (suppl.), 245-254.
    • (2003) Nat. Genet. , vol.33 , Issue.SUPPL , pp. 245-254
    • Jaenisch, R.1
  • 16
    • 40349100412 scopus 로고    scopus 로고
    • The identification of microRNAs in a genomically unstable region of human chromosome 8q24
    • Huppi, K. et al. (2008) The identification of microRNAs in a genomically unstable region of human chromosome 8q24. Mol. Cancer Res., 6, 212-221.
    • (2008) Mol. Cancer Res. , vol.6 , pp. 212-221
    • Huppi, K.1
  • 17
    • 52449115337 scopus 로고    scopus 로고
    • MicroRNAs in development and disease
    • Erson, A.E. et al. (2008) MicroRNAs in development and disease. Clin. Genet., 74, 296-306.
    • (2008) Clin. Genet. , vol.74 , pp. 296-306
    • Erson, A.E.1
  • 18
    • 57349165798 scopus 로고    scopus 로고
    • DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation
    • Tamminga, J. et al. (2008) DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation. Cell Cycle, 7, 3731-3736.
    • (2008) Cell Cycle , vol.7 , pp. 3731-3736
    • Tamminga, J.1
  • 19
    • 44349147908 scopus 로고    scopus 로고
    • Paternal cranial irradiation induces distant by- stander DNA damage in the germline and leads to epigenetic alterations in the offspring
    • Tamminga, J. et al. (2008) Paternal cranial irradiation induces distant by- stander DNA damage in the germline and leads to epigenetic alterations in the offspring. Cell Cycle, 7, 1238-1245.
    • (2008) Cell Cycle , vol.7 , pp. 1238-1245
    • Tamminga, J.1
  • 20
    • 33748335527 scopus 로고    scopus 로고
    • Epigenetic dysregulation underlies radiation- induced transgenerational genome instability in vivo
    • Koturbash, I. et al. (2006) Epigenetic dysregulation underlies radiation- induced transgenerational genome instability in vivo. Int. J. Radiat. Oncol. Biol. Phys., 66, 327-330.
    • (2006) Int. J. Radiat. Oncol. Biol. Phys. , vol.66 , pp. 327-330
    • Koturbash, I.1
  • 21
    • 0036313167 scopus 로고    scopus 로고
    • Myeloid B and T lymphoid and mixed lineage thymic lymphomas in the irradiated mouse
    • Boulton, E. et al. (2002) Myeloid, B and T lymphoid and mixed lineage thymic lymphomas in the irradiated mouse. Carcinogenesis, 23, 1079-1085.
    • (2002) Carcinogenesis , vol.23 , pp. 1079-1085
    • Boulton, E.1
  • 22
    • 33749626120 scopus 로고    scopus 로고
    • Radiation-induced transgenerational alterations in genome stability and DNA damage
    • Barber, R.C. et al. (2006) Radiation-induced transgenerational alterations in genome stability and DNA damage. Oncogene, 25, 7336-7342.
    • (2006) Oncogene , vol.25 , pp. 7336-7342
    • Barber, R.C.1
  • 23
    • 0037139224 scopus 로고    scopus 로고
    • A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus
    • Yauk, C.L. et al. (2002) A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus. Mutat. Res., 500, 147-156.
    • (2002) Mutat. Res. , vol.500 , pp. 147-156
    • Yauk, C.L.1
  • 24
    • 0037716763 scopus 로고    scopus 로고
    • Radiation-induced-thymic lymphoma occurs in young, but not in old mice
    • Utsuyama, M. et al. (2003) Radiation-induced-thymic lymphoma occurs in young, but not in old mice. Exp. Mol. Pathol., 74, 319-325.
    • (2003) Exp. Mol. Pathol. , vol.74 , pp. 319-325
    • Utsuyama, M.1
  • 25
    • 60849116183 scopus 로고    scopus 로고
    • Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner
    • Ilnytskyy, Y. et al. (2009) Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner. Environ. Mol. Mutagen., 50, 105-113.
    • (2009) Environ. Mol. Mutagen. , vol.50 , pp. 105-113
    • Ilnytskyy, Y.1
  • 26
    • 54449092059 scopus 로고    scopus 로고
    • Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism
    • Ilnytskyy, Y. et al. (2008) Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism. Biochem. Biophys. Res. Commun., 377, 41-45.
    • (2008) Biochem. Biophys. Res. Commun. , vol.377 , pp. 41-45
    • Ilnytskyy, Y.1
  • 27
    • 45849090741 scopus 로고    scopus 로고
    • Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice
    • Koturbash, I. et al. (2008) Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice. Cell Cycle, 7, 1658-1667.
    • (2008) Cell Cycle , vol.7 , pp. 1658-1667
    • Koturbash, I.1
  • 28
    • 49149121957 scopus 로고    scopus 로고
    • Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells
    • Chang, J. et al. (2008) Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells. J. Virol., 82, 8215-8223.
    • (2008) J. Virol. , vol.82 , pp. 8215-8223
    • Chang, J.1
  • 29
    • 62849110531 scopus 로고    scopus 로고
    • Identification and expression analysis of miRNAs during batch culture of HEK-293 cells
    • Koh, T.C. et al. (2009) Identification and expression analysis of miRNAs during batch culture of HEK-293 cells. J. Biotechnol., 140, 149-155.
    • (2009) J. Biotechnol. , vol.140 , pp. 149-155
    • Koh, T.C.1
  • 30
    • 15444372817 scopus 로고    scopus 로고
    • The profile of repeat-associated histone lysine methylation states in the mouse epigenome
    • Martens, J.H. et al. (2005) The profile of repeat-associated histone lysine methylation states in the mouse epigenome. EMBO J., 24, 800-812.
    • (2005) EMBO J , vol.24 , pp. 800-812
    • Martens, J.H.1
  • 31
    • 35649020283 scopus 로고    scopus 로고
    • MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
    • Fabbri, M. et al. (2007) MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc. Natl Acad. Sci. USA, 104, 15805-15810.
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 15805-15810
    • Fabbri, M.1
  • 32
    • 1542563409 scopus 로고    scopus 로고
    • Initial sequencing and comparative analysis of the mouse genome
    • Waterston, R.H. et al. (2002) Initial sequencing and comparative analysis of the mouse genome. Nature, 420, 520-562.
    • (2002) Nature , vol.420 , pp. 520-562
    • Waterston, R.H.1
  • 33
    • 0026634757 scopus 로고
    • McrBC: a multisubunit GTP-dependent restriction endonuclease
    • Sutherland, E. et al. (1992) McrBC: a multisubunit GTP-dependent restriction endonuclease. J. Mol. Biol., 225, 327-348.
    • (1992) J. Mol. Biol. , vol.225 , pp. 327-348
    • Sutherland, E.1
  • 34
    • 27944504788 scopus 로고    scopus 로고
    • Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia
    • Roman-Gomez, J. et al. (2005) Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene, 24, 7213-7223.
    • (2005) Oncogene , vol.24 , pp. 7213-7223
    • Roman-Gomez, J.1
  • 35
    • 38049164130 scopus 로고    scopus 로고
    • Activation and transposition of endogenous retro-viral elements in hypomethylation induced tumors in mice
    • Howard, G. et al. (2008) Activation and transposition of endogenous retro-viral elements in hypomethylation induced tumors in mice. Oncogene, 27, 404-408.
    • (2008) Oncogene , vol.27 , pp. 404-408
    • Howard, G.1
  • 36
    • 34250747441 scopus 로고    scopus 로고
    • Origins and consequences of DNA damage in male germ cells
    • Aitken, R.J. et al. (2007) Origins and consequences of DNA damage in male germ cells. Reprod. Biomed. Online, 14, 727-733.
    • (2007) Reprod. Biomed. Online , vol.14 , pp. 727-733
    • Aitken, R.J.1
  • 37
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intra-genomic parasites
    • Yoder, J.A. et al. (1997) Cytosine methylation and the ecology of intra-genomic parasites. Trends Genet., 13, 335-340.
    • (1997) Trends Genet , vol.13 , pp. 335-340
    • Yoder, J.A.1
  • 38
    • 34848911647 scopus 로고    scopus 로고
    • DNA methylation: the nuts and bolts of repression
    • Miranda, T.B. et al. (2007) DNA methylation: the nuts and bolts of repression. J. Cell. Physiol., 213, 384-390.
    • (2007) J. Cell. Physiol. , vol.213 , pp. 384-390
    • Miranda, T.B.1
  • 39
    • 0035890090 scopus 로고    scopus 로고
    • Lsh, a member of the SNF2 family, is required for genome-wide methylation
    • Dennis, K. et al. (2001) Lsh, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev., 15, 2940-2944.
    • (2001) Genes Dev , vol.15 , pp. 2940-2944
    • Dennis, K.1
  • 40
    • 4644250896 scopus 로고    scopus 로고
    • Lsh, an epigenetic guardian of repetitive elements
    • Huang, J. et al. (2004) Lsh, an epigenetic guardian of repetitive elements. Nucleic Acids Res., 32, 5019-5028.
    • (2004) Nucleic Acids Res , vol.32 , pp. 5019-5028
    • Huang, J.1
  • 41
    • 0141642008 scopus 로고    scopus 로고
    • Lsh, a modulator of CpG methylation, is crucial for normal histone methylation
    • Yan, Q. et al. (2003) Lsh, a modulator of CpG methylation, is crucial for normal histone methylation. EMBO J., 22, 5154-5162.
    • (2003) EMBO J , vol.22 , pp. 5154-5162
    • Yan, Q.1
  • 42
    • 31444436545 scopus 로고    scopus 로고
    • Lsh is involved in de novo methylation of DNA
    • Zhu, H. et al. (2006) Lsh is involved in de novo methylation of DNA. EMBO J., 25, 335-345.
    • (2006) EMBO J , vol.25 , pp. 335-345
    • Zhu, H.1
  • 43
    • 27744566944 scopus 로고    scopus 로고
    • Lsh, a guardian of heterochromatin at repeat elements
    • Muegge, K. (2005) Lsh, a guardian of heterochromatin at repeat elements. Biochem. Cell Biol., 83, 548-554.
    • (2005) Biochem. Cell Biol. , vol.83 , pp. 548-554
    • Muegge, K.1
  • 44
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: genomics, biogenesis, mechanism, and function
    • Bartel, D.P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 45
    • 33644659734 scopus 로고    scopus 로고
    • Mammalian microRNAs: a small world for fine-tuning gene expression
    • Sevignani, C. et al. (2006) Mammalian microRNAs: a small world for fine-tuning gene expression. Mamm. Genome, 17, 189-202.
    • (2006) Mamm. Genome , vol.17 , pp. 189-202
    • Sevignani, C.1
  • 46
    • 41349096445 scopus 로고    scopus 로고
    • Gene regulation by transcription factors and microRNAs
    • Hobert, O. (2008) Gene regulation by transcription factors and microRNAs. Science, 319, 1785-1786.
    • (2008) Science , vol.319 , pp. 1785-1786
    • Hobert, O.1
  • 47
    • 38349169664 scopus 로고    scopus 로고
    • Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
    • Filipowicz, W. et al. (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet., 9, 102-114.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 102-114
    • Filipowicz, W.1
  • 48
    • 40949100837 scopus 로고    scopus 로고
    • A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
    • Benetti, R. et al. (2008) A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat. Struct. Mol. Biol., 15, 998.
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 998
    • Benetti, R.1
  • 49
    • 40949130398 scopus 로고    scopus 로고
    • MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
    • Sinkkonen, L. et al. (2008) MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat. Struct. Mol. Biol., 15, 259-67.
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 259-267
    • Sinkkonen, L.1
  • 50
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
    • Kovalchuk, O. et al. (2008) Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol. Cancer Ther., 7, 2152-2159.
    • (2008) Mol. Cancer Ther. , vol.7 , pp. 2152-2159
    • Kovalchuk, O.1
  • 51
    • 38549124383 scopus 로고    scopus 로고
    • The microRNA.org resource: targets and expression
    • Betel, D. et al. (2008) The microRNA.org resource: targets and expression. Nucleic Acids Res., 36, D149-D53.
    • (2008) Nucleic Acids Res , vol.36
    • Betel, D.1
  • 52
    • 33847673752 scopus 로고    scopus 로고
    • Assessing human germ-cell mutagenesis in the Postgenome Era: a celebration of the legacy of William Lawson (Bill) Russell
    • Wyrobek, A.J. et al. (2007) Assessing human germ-cell mutagenesis in the Postgenome Era: a celebration of the legacy of William Lawson (Bill) Russell. Environ. Mol. Mutagen., 48, 71-95.
    • (2007) Environ. Mol. Mutagen. , vol.48 , pp. 71-95
    • Wyrobek, A.J.1
  • 53
    • 49249126168 scopus 로고    scopus 로고
    • DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development
    • Fan, T. et al. (2008) DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development. Epigenetics, 3, 134-142.
    • (2008) Epigenetics , vol.3 , pp. 134-142
    • Fan, T.1
  • 54
    • 37549061829 scopus 로고    scopus 로고
    • LSH cooperates with DNA methyltransferases to repress transcription
    • Myant, K. et al. (2008) LSH cooperates with DNA methyltransferases to repress transcription. Mol. Cell. Biol., 28, 215-226.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 215-226
    • Myant, K.1
  • 55
    • 32044455298 scopus 로고    scopus 로고
    • Large-scale structure of genomic methylation patterns
    • Rollins, R.A. et al. (2006) Large-scale structure of genomic methylation patterns. Genome Res., 16, 157-163.
    • (2006) Genome Res , vol.16 , pp. 157-163
    • Rollins, R.A.1
  • 56
    • 38449094093 scopus 로고    scopus 로고
    • Evidence for a role of paternal exposures in developmental toxicity
    • Cordier, S. (2008) Evidence for a role of paternal exposures in developmental toxicity. Basic Clin. Pharmacol. Toxicol., 102, 176-181.
    • (2008) Basic Clin. Pharmacol. Toxicol. , vol.102 , pp. 176-181
    • Cordier, S.1
  • 57
    • 20344385787 scopus 로고    scopus 로고
    • Epigenetic transgenerational actions of endocrine disruptors and male fertility
    • Anway, M.D. et al. (2005) Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science, 308, 1466-1469.
    • (2005) Science , vol.308 , pp. 1466-1469
    • Anway, M.D.1
  • 58
    • 0034598784 scopus 로고    scopus 로고
    • Demethylation of the zygotic paternal genome
    • Mayer, W. et al. (2000) Demethylation of the zygotic paternal genome. Nature, 403, 501-502.
    • (2000) Nature , vol.403 , pp. 501-502
    • Mayer, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.