-
1
-
-
33744917239
-
The offspring of irradiated parents, are they stable? Mutat
-
Barber, R.C. et al. (2006) The offspring of irradiated parents, are they stable? Mutat. Res., 598, 50-60.
-
(2006)
Res
, vol.598
, pp. 50-60
-
-
Barber, R.C.1
-
2
-
-
0242574353
-
Radiation-induced transgenerational instability
-
Dubrova, Y.E. (2003) Radiation-induced transgenerational instability. Oncogene, 22, 7087-7093.
-
(2003)
Oncogene
, vol.22
, pp. 7087-7093
-
-
Dubrova, Y.E.1
-
3
-
-
33749544688
-
Radiation induced dynamic mutations and transgenerational effects
-
Niwa, O. (2006) Radiation induced dynamic mutations and transgenerational effects. J. Radiat. Res. (Tokyo), 47 (suppl. B), B25-B30.
-
(2006)
J. Radiat. Res. (Tokyo)
, vol.47
, Issue.SUPPL. B
-
-
Niwa, O.1
-
4
-
-
0038640479
-
Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects
-
Morgan, W.F. (2003) Non-targeted and delayed effects of exposure to ionizing radiation: II. Radiation-induced genomic instability and bystander effects in vivo, clastogenic factors and transgenerational effects. Radiat. Res., 159, 581-596.
-
(2003)
Radiat. Res.
, vol.159
, pp. 581-596
-
-
Morgan, W.F.1
-
6
-
-
42949170867
-
Paternal exposure to ethylnitrosourea results in transgenerational genomic instability in mice
-
Dubrova, Y.E. et al. (2008) Paternal exposure to ethylnitrosourea results in transgenerational genomic instability in mice. Environ. Mol. Mutagen., 49, 308-311.
-
(2008)
Environ. Mol. Mutagen.
, vol.49
, pp. 308-311
-
-
Dubrova, Y.E.1
-
7
-
-
47849103962
-
Transgenerational effects from exposure to environmental toxic substances
-
Nomura, T. (2008) Transgenerational effects from exposure to environmental toxic substances. Mutat. Res., 659, 185-193.
-
(2008)
Mutat. Res.
, vol.659
, pp. 185-193
-
-
Nomura, T.1
-
8
-
-
45549102409
-
Single-molecule PCR analysis of germ line mutation induction by anticancer drugs in mice
-
Glen, C.D. et al. (2008) Single-molecule PCR analysis of germ line mutation induction by anticancer drugs in mice. Cancer Res., 68, 3630-3636.
-
(2008)
Cancer Res
, vol.68
, pp. 3630-3636
-
-
Glen, C.D.1
-
9
-
-
20444452498
-
Impact of paternal exposure to chemotherapy on offspring in the rat
-
Hales, B.F. et al. (2005) Impact of paternal exposure to chemotherapy on offspring in the rat. J. Natl Cancer Inst. Monogr., 34, 28-31.
-
(2005)
J. Natl Cancer Inst. Monogr.
, vol.34
, pp. 28-31
-
-
Hales, B.F.1
-
10
-
-
0345686425
-
Long-term genetic effects of radiation exposure
-
Dubrova, Y.E. (2003) Long-term genetic effects of radiation exposure. Mutat. Res., 544, 433-439.
-
(2003)
Mutat. Res.
, vol.544
, pp. 433-439
-
-
Dubrova, Y.E.1
-
11
-
-
0342313475
-
Transgenerational mutation by radiation
-
Dubrova, Y.E. et al. (2000) Transgenerational mutation by radiation. Nature, 405, 37.
-
(2000)
Nature
, vol.405
, pp. 37
-
-
Dubrova, Y.E.1
-
12
-
-
24044503756
-
Gamma irradiation of Type B spermatogonia leads to heritable genomic instability in four generations of mice
-
Baulch, J.E. et al. (2005) Gamma irradiation of Type B spermatogonia leads to heritable genomic instability in four generations of mice. Mutagenesis, 20, 337-43.
-
(2005)
Mutagenesis
, vol.20
, pp. 337-343
-
-
Baulch, J.E.1
-
13
-
-
2642531973
-
Epigenetics in human disease and prospects for epigenetic therapy
-
Egger, G. et al. (2004) Epigenetics in human disease and prospects for epigenetic therapy. Nature, 429, 457-463.
-
(2004)
Nature
, vol.429
, pp. 457-463
-
-
Egger, G.1
-
14
-
-
40949093544
-
Epigenetics at the epicenter of modern medicine
-
Feinberg, A.P. (2008) Epigenetics at the epicenter of modern medicine. JAMA, 299, 1345-1350.
-
(2008)
JAMA
, vol.299
, pp. 1345-1350
-
-
Feinberg, A.P.1
-
15
-
-
0037372003
-
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
-
Jaenisch, R. et al. (2003) Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat. Genet., 33 (suppl.), 245-254.
-
(2003)
Nat. Genet.
, vol.33
, Issue.SUPPL
, pp. 245-254
-
-
Jaenisch, R.1
-
16
-
-
40349100412
-
The identification of microRNAs in a genomically unstable region of human chromosome 8q24
-
Huppi, K. et al. (2008) The identification of microRNAs in a genomically unstable region of human chromosome 8q24. Mol. Cancer Res., 6, 212-221.
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 212-221
-
-
Huppi, K.1
-
17
-
-
52449115337
-
MicroRNAs in development and disease
-
Erson, A.E. et al. (2008) MicroRNAs in development and disease. Clin. Genet., 74, 296-306.
-
(2008)
Clin. Genet.
, vol.74
, pp. 296-306
-
-
Erson, A.E.1
-
18
-
-
57349165798
-
DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation
-
Tamminga, J. et al. (2008) DNA damage-induced upregulation of miR-709 in the germline downregulates BORIS to counteract aberrant DNA hypomethylation. Cell Cycle, 7, 3731-3736.
-
(2008)
Cell Cycle
, vol.7
, pp. 3731-3736
-
-
Tamminga, J.1
-
19
-
-
44349147908
-
Paternal cranial irradiation induces distant by- stander DNA damage in the germline and leads to epigenetic alterations in the offspring
-
Tamminga, J. et al. (2008) Paternal cranial irradiation induces distant by- stander DNA damage in the germline and leads to epigenetic alterations in the offspring. Cell Cycle, 7, 1238-1245.
-
(2008)
Cell Cycle
, vol.7
, pp. 1238-1245
-
-
Tamminga, J.1
-
20
-
-
33748335527
-
Epigenetic dysregulation underlies radiation- induced transgenerational genome instability in vivo
-
Koturbash, I. et al. (2006) Epigenetic dysregulation underlies radiation- induced transgenerational genome instability in vivo. Int. J. Radiat. Oncol. Biol. Phys., 66, 327-330.
-
(2006)
Int. J. Radiat. Oncol. Biol. Phys.
, vol.66
, pp. 327-330
-
-
Koturbash, I.1
-
21
-
-
0036313167
-
Myeloid B and T lymphoid and mixed lineage thymic lymphomas in the irradiated mouse
-
Boulton, E. et al. (2002) Myeloid, B and T lymphoid and mixed lineage thymic lymphomas in the irradiated mouse. Carcinogenesis, 23, 1079-1085.
-
(2002)
Carcinogenesis
, vol.23
, pp. 1079-1085
-
-
Boulton, E.1
-
22
-
-
33749626120
-
Radiation-induced transgenerational alterations in genome stability and DNA damage
-
Barber, R.C. et al. (2006) Radiation-induced transgenerational alterations in genome stability and DNA damage. Oncogene, 25, 7336-7342.
-
(2006)
Oncogene
, vol.25
, pp. 7336-7342
-
-
Barber, R.C.1
-
23
-
-
0037139224
-
A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus
-
Yauk, C.L. et al. (2002) A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus. Mutat. Res., 500, 147-156.
-
(2002)
Mutat. Res.
, vol.500
, pp. 147-156
-
-
Yauk, C.L.1
-
24
-
-
0037716763
-
Radiation-induced-thymic lymphoma occurs in young, but not in old mice
-
Utsuyama, M. et al. (2003) Radiation-induced-thymic lymphoma occurs in young, but not in old mice. Exp. Mol. Pathol., 74, 319-325.
-
(2003)
Exp. Mol. Pathol.
, vol.74
, pp. 319-325
-
-
Utsuyama, M.1
-
25
-
-
60849116183
-
Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner
-
Ilnytskyy, Y. et al. (2009) Radiation-induced bystander effects in vivo are epigenetically regulated in a tissue-specific manner. Environ. Mol. Mutagen., 50, 105-113.
-
(2009)
Environ. Mol. Mutagen.
, vol.50
, pp. 105-113
-
-
Ilnytskyy, Y.1
-
26
-
-
54449092059
-
Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism
-
Ilnytskyy, Y. et al. (2008) Altered microRNA expression patterns in irradiated hematopoietic tissues suggest a sex-specific protective mechanism. Biochem. Biophys. Res. Commun., 377, 41-45.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.377
, pp. 41-45
-
-
Ilnytskyy, Y.1
-
27
-
-
45849090741
-
Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice
-
Koturbash, I. et al. (2008) Sex-specific microRNAome deregulation in the shielded bystander spleen of cranially exposed mice. Cell Cycle, 7, 1658-1667.
-
(2008)
Cell Cycle
, vol.7
, pp. 1658-1667
-
-
Koturbash, I.1
-
28
-
-
49149121957
-
Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells
-
Chang, J. et al. (2008) Liver-specific microRNA miR-122 enhances the replication of hepatitis C virus in nonhepatic cells. J. Virol., 82, 8215-8223.
-
(2008)
J. Virol.
, vol.82
, pp. 8215-8223
-
-
Chang, J.1
-
29
-
-
62849110531
-
Identification and expression analysis of miRNAs during batch culture of HEK-293 cells
-
Koh, T.C. et al. (2009) Identification and expression analysis of miRNAs during batch culture of HEK-293 cells. J. Biotechnol., 140, 149-155.
-
(2009)
J. Biotechnol.
, vol.140
, pp. 149-155
-
-
Koh, T.C.1
-
30
-
-
15444372817
-
The profile of repeat-associated histone lysine methylation states in the mouse epigenome
-
Martens, J.H. et al. (2005) The profile of repeat-associated histone lysine methylation states in the mouse epigenome. EMBO J., 24, 800-812.
-
(2005)
EMBO J
, vol.24
, pp. 800-812
-
-
Martens, J.H.1
-
31
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
Fabbri, M. et al. (2007) MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc. Natl Acad. Sci. USA, 104, 15805-15810.
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 15805-15810
-
-
Fabbri, M.1
-
32
-
-
1542563409
-
Initial sequencing and comparative analysis of the mouse genome
-
Waterston, R.H. et al. (2002) Initial sequencing and comparative analysis of the mouse genome. Nature, 420, 520-562.
-
(2002)
Nature
, vol.420
, pp. 520-562
-
-
Waterston, R.H.1
-
33
-
-
0026634757
-
McrBC: a multisubunit GTP-dependent restriction endonuclease
-
Sutherland, E. et al. (1992) McrBC: a multisubunit GTP-dependent restriction endonuclease. J. Mol. Biol., 225, 327-348.
-
(1992)
J. Mol. Biol.
, vol.225
, pp. 327-348
-
-
Sutherland, E.1
-
34
-
-
27944504788
-
Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia
-
Roman-Gomez, J. et al. (2005) Promoter hypomethylation of the LINE-1 retrotransposable elements activates sense/antisense transcription and marks the progression of chronic myeloid leukemia. Oncogene, 24, 7213-7223.
-
(2005)
Oncogene
, vol.24
, pp. 7213-7223
-
-
Roman-Gomez, J.1
-
35
-
-
38049164130
-
Activation and transposition of endogenous retro-viral elements in hypomethylation induced tumors in mice
-
Howard, G. et al. (2008) Activation and transposition of endogenous retro-viral elements in hypomethylation induced tumors in mice. Oncogene, 27, 404-408.
-
(2008)
Oncogene
, vol.27
, pp. 404-408
-
-
Howard, G.1
-
36
-
-
34250747441
-
Origins and consequences of DNA damage in male germ cells
-
Aitken, R.J. et al. (2007) Origins and consequences of DNA damage in male germ cells. Reprod. Biomed. Online, 14, 727-733.
-
(2007)
Reprod. Biomed. Online
, vol.14
, pp. 727-733
-
-
Aitken, R.J.1
-
37
-
-
0030840954
-
Cytosine methylation and the ecology of intra-genomic parasites
-
Yoder, J.A. et al. (1997) Cytosine methylation and the ecology of intra-genomic parasites. Trends Genet., 13, 335-340.
-
(1997)
Trends Genet
, vol.13
, pp. 335-340
-
-
Yoder, J.A.1
-
38
-
-
34848911647
-
DNA methylation: the nuts and bolts of repression
-
Miranda, T.B. et al. (2007) DNA methylation: the nuts and bolts of repression. J. Cell. Physiol., 213, 384-390.
-
(2007)
J. Cell. Physiol.
, vol.213
, pp. 384-390
-
-
Miranda, T.B.1
-
39
-
-
0035890090
-
Lsh, a member of the SNF2 family, is required for genome-wide methylation
-
Dennis, K. et al. (2001) Lsh, a member of the SNF2 family, is required for genome-wide methylation. Genes Dev., 15, 2940-2944.
-
(2001)
Genes Dev
, vol.15
, pp. 2940-2944
-
-
Dennis, K.1
-
40
-
-
4644250896
-
Lsh, an epigenetic guardian of repetitive elements
-
Huang, J. et al. (2004) Lsh, an epigenetic guardian of repetitive elements. Nucleic Acids Res., 32, 5019-5028.
-
(2004)
Nucleic Acids Res
, vol.32
, pp. 5019-5028
-
-
Huang, J.1
-
41
-
-
0141642008
-
Lsh, a modulator of CpG methylation, is crucial for normal histone methylation
-
Yan, Q. et al. (2003) Lsh, a modulator of CpG methylation, is crucial for normal histone methylation. EMBO J., 22, 5154-5162.
-
(2003)
EMBO J
, vol.22
, pp. 5154-5162
-
-
Yan, Q.1
-
42
-
-
31444436545
-
Lsh is involved in de novo methylation of DNA
-
Zhu, H. et al. (2006) Lsh is involved in de novo methylation of DNA. EMBO J., 25, 335-345.
-
(2006)
EMBO J
, vol.25
, pp. 335-345
-
-
Zhu, H.1
-
43
-
-
27744566944
-
Lsh, a guardian of heterochromatin at repeat elements
-
Muegge, K. (2005) Lsh, a guardian of heterochromatin at repeat elements. Biochem. Cell Biol., 83, 548-554.
-
(2005)
Biochem. Cell Biol.
, vol.83
, pp. 548-554
-
-
Muegge, K.1
-
44
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel, D.P. (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 116, 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
45
-
-
33644659734
-
Mammalian microRNAs: a small world for fine-tuning gene expression
-
Sevignani, C. et al. (2006) Mammalian microRNAs: a small world for fine-tuning gene expression. Mamm. Genome, 17, 189-202.
-
(2006)
Mamm. Genome
, vol.17
, pp. 189-202
-
-
Sevignani, C.1
-
46
-
-
41349096445
-
Gene regulation by transcription factors and microRNAs
-
Hobert, O. (2008) Gene regulation by transcription factors and microRNAs. Science, 319, 1785-1786.
-
(2008)
Science
, vol.319
, pp. 1785-1786
-
-
Hobert, O.1
-
47
-
-
38349169664
-
Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?
-
Filipowicz, W. et al. (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet., 9, 102-114.
-
(2008)
Nat. Rev. Genet.
, vol.9
, pp. 102-114
-
-
Filipowicz, W.1
-
48
-
-
40949100837
-
A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases
-
Benetti, R. et al. (2008) A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases. Nat. Struct. Mol. Biol., 15, 998.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 998
-
-
Benetti, R.1
-
49
-
-
40949130398
-
MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells
-
Sinkkonen, L. et al. (2008) MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells. Nat. Struct. Mol. Biol., 15, 259-67.
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 259-267
-
-
Sinkkonen, L.1
-
50
-
-
51049104524
-
Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin
-
Kovalchuk, O. et al. (2008) Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol. Cancer Ther., 7, 2152-2159.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 2152-2159
-
-
Kovalchuk, O.1
-
51
-
-
38549124383
-
The microRNA.org resource: targets and expression
-
Betel, D. et al. (2008) The microRNA.org resource: targets and expression. Nucleic Acids Res., 36, D149-D53.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Betel, D.1
-
52
-
-
33847673752
-
Assessing human germ-cell mutagenesis in the Postgenome Era: a celebration of the legacy of William Lawson (Bill) Russell
-
Wyrobek, A.J. et al. (2007) Assessing human germ-cell mutagenesis in the Postgenome Era: a celebration of the legacy of William Lawson (Bill) Russell. Environ. Mol. Mutagen., 48, 71-95.
-
(2007)
Environ. Mol. Mutagen.
, vol.48
, pp. 71-95
-
-
Wyrobek, A.J.1
-
53
-
-
49249126168
-
DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development
-
Fan, T. et al. (2008) DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development. Epigenetics, 3, 134-142.
-
(2008)
Epigenetics
, vol.3
, pp. 134-142
-
-
Fan, T.1
-
54
-
-
37549061829
-
LSH cooperates with DNA methyltransferases to repress transcription
-
Myant, K. et al. (2008) LSH cooperates with DNA methyltransferases to repress transcription. Mol. Cell. Biol., 28, 215-226.
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 215-226
-
-
Myant, K.1
-
55
-
-
32044455298
-
Large-scale structure of genomic methylation patterns
-
Rollins, R.A. et al. (2006) Large-scale structure of genomic methylation patterns. Genome Res., 16, 157-163.
-
(2006)
Genome Res
, vol.16
, pp. 157-163
-
-
Rollins, R.A.1
-
56
-
-
38449094093
-
Evidence for a role of paternal exposures in developmental toxicity
-
Cordier, S. (2008) Evidence for a role of paternal exposures in developmental toxicity. Basic Clin. Pharmacol. Toxicol., 102, 176-181.
-
(2008)
Basic Clin. Pharmacol. Toxicol.
, vol.102
, pp. 176-181
-
-
Cordier, S.1
-
57
-
-
20344385787
-
Epigenetic transgenerational actions of endocrine disruptors and male fertility
-
Anway, M.D. et al. (2005) Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science, 308, 1466-1469.
-
(2005)
Science
, vol.308
, pp. 1466-1469
-
-
Anway, M.D.1
-
58
-
-
0034598784
-
Demethylation of the zygotic paternal genome
-
Mayer, W. et al. (2000) Demethylation of the zygotic paternal genome. Nature, 403, 501-502.
-
(2000)
Nature
, vol.403
, pp. 501-502
-
-
Mayer, W.1
|