Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

Nature Biotechnology

Volumn 28, Issue 4, 2010, Pages 341-347

  Ma, Li ^a,b   Reinhardt, Ferenc ^a   Pan, Elizabeth ^a   Soutschek, Jürgen ^c   Bhat, Balkrishen ^c   Marcusson, Eric G ^c   Teruya Feldstein, Julie ^d   Bell, George W ^a   Weinberg, Robert A ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c REGULUS THERAPEUTICS   (United States)

^d MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTAGOMIRS; BREAST CANCER; CHEMICALLY MODIFIED; IN-VITRO; LUNG METASTASIS; MAMMARY TUMORS; MICRORNAS; NON-HUMAN PRIMATE; NORMAL TISSUE; SEQUENCE-SPECIFIC MANNER;

BEARINGS (STRUCTURAL); MAMMALS; TUMORS;

PATHOLOGY;

ANTAGOMIR; MICRORNA; MICRORNA 10B; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

ARTICLE; BREAST TUMOR; GENE SILENCING; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC THERAPY; TUMOR GROWTH;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICRORNAS; NEOPLASM METASTASIS; TREATMENT OUTCOME;

ANIMALIA; MUS; PRIMATES; RODENTIA;

EID: 77950665077     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt.1618     Document Type: Article

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