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Volumn 13, Issue 6, 2006, Pages 496-502

Anti-miRNA oligonucleotides (AMOs): Ammunition to target miRNAs implicated in human disease?

Author keywords

AMO; Anti miRNA oligonucleotide; Antisense oligonucleotides; microRNA; miRNA; RNAi

Indexed keywords

2' O METHOXYETHYL MICRORNA ANTISENSE OLIGONUCLEOTIDE; 2' O METHYL MICRORNA ANTISENSE OLIGONUCLEOTIDE; ANTISENSE OLIGONUCLEOTIDE; LOCKED NUCLEIC ACID MICRORNA ANTISENSE OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

EID: 33645135862     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/sj.gt.3302654     Document Type: Review
Times cited : (361)

References (85)
  • 1
    • 4644309196 scopus 로고    scopus 로고
    • The functions of animal microRNAs
    • Ambros V. The functions of animal microRNAs. Nature 2004; 431: 350-355.
    • (2004) Nature , vol.431 , pp. 350-355
    • Ambros, V.1
  • 2
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: Genomics, biogenesis, mechanism, and function. Cell 2004; 116: 281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 4
    • 18344369543 scopus 로고    scopus 로고
    • MicroRNA biogenesis: Coordinated cropping and dicing
    • Kim VN. MicroRNA biogenesis: Coordinated cropping and dicing. Nat Rev Mol Cell Biol 2005; 6: 376-385.
    • (2005) Nat Rev Mol Cell Biol , vol.6 , pp. 376-385
    • Kim, V.N.1
  • 5
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Lee Y, Jeon K, Lee JT, Kim S, Kim VN. MicroRNA maturation: Stepwise processing and subcellular localization. EMBO J 2002; 21: 4663-4670.
    • (2002) EMBO J , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.T.3    Kim, S.4    Kim, V.N.5
  • 6
    • 9344235449 scopus 로고    scopus 로고
    • Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs
    • Cai X, Hagedorn CH, Cullen BR. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 2004; 10: 1957-1966.
    • (2004) RNA , vol.10 , pp. 1957-1966
    • Cai, X.1    Hagedorn, C.H.2    Cullen, B.R.3
  • 7
    • 8144225486 scopus 로고    scopus 로고
    • MicroRNA genes are transcribed by RNA polymerase II
    • Lee Y, Kim M, Han J, Yeom KH, Lee S, Baek SH et al. MicroRNA genes are transcribed by RNA polymerase II. EMBO J 2004; 23: 4051-4060.
    • (2004) EMBO J , vol.23 , pp. 4051-4060
    • Lee, Y.1    Kim, M.2    Han, J.3    Yeom, K.H.4    Lee, S.5    Baek, S.H.6
  • 8
    • 0141843656 scopus 로고    scopus 로고
    • The nuclear RNase III Drosha initiates microRNA processing
    • Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J et al. The nuclear RNase III Drosha initiates microRNA processing. Nature 2003; 425: 415-419.
    • (2003) Nature , vol.425 , pp. 415-419
    • Lee, Y.1    Ahn, C.2    Han, J.3    Choi, H.4    Kim, J.5    Yim, J.6
  • 9
    • 0347361541 scopus 로고    scopus 로고
    • Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
    • Yi R, Qin Y, Macara IG, Cullen BR. Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes Dev 2003; 17: 3011-3016.
    • (2003) Genes Dev , vol.17 , pp. 3011-3016
    • Yi, R.1    Qin, Y.2    Macara, I.G.3    Cullen, B.R.4
  • 11
    • 0035905766 scopus 로고    scopus 로고
    • Role for a bidentate ribonuclease in the initiation step of RNA interference
    • Bernstein E, Caudy AA, Hammond SM, Hannon GJ. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 2001; 409: 363-366.
    • (2001) Nature , vol.409 , pp. 363-366
    • Bernstein, E.1    Caudy, A.A.2    Hammond, S.M.3    Hannon, G.J.4
  • 12
    • 0035800521 scopus 로고    scopus 로고
    • A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA
    • Hutvagner G, McLachlan J, Pasquinelli AE, Balint E, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science 2001; 293: 834-838.
    • (2001) Science , vol.293 , pp. 834-838
    • Hutvagner, G.1    McLachlan, J.2    Pasquinelli, A.E.3    Balint, E.4    Tuschl, T.5    Zamore, P.D.6
  • 13
    • 0037144546 scopus 로고    scopus 로고
    • A microRNA in a multiple-turnover RNAi enzyme complex
    • Hutvagner G, Zamore PD. A microRNA in a multiple-turnover RNAi enzyme complex. Science 2002; 297: 2056-2060.
    • (2002) Science , vol.297 , pp. 2056-2060
    • Hutvagner, G.1    Zamore, P.D.2
  • 14
    • 0037031576 scopus 로고    scopus 로고
    • Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
    • Martinez J, Patkaniowska A, Urlaub H, Luhrmann R, Tuschl T. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi. Cell 2002; 110: 563-574.
    • (2002) Cell , vol.110 , pp. 563-574
    • Martinez, J.1    Patkaniowska, A.2    Urlaub, H.3    Luhrmann, R.4    Tuschl, T.5
  • 15
    • 13244278197 scopus 로고    scopus 로고
    • siRNA and miRNA: An insight into RISCs
    • Tang G. siRNA and miRNA: An insight into RISCs. Trends Biochem Sci 2005; 30: 106-114.
    • (2005) Trends Biochem Sci , vol.30 , pp. 106-114
    • Tang, G.1
  • 16
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • Yekta S, Shih IH, Bartel DP. MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004; 304: 594-596.
    • (2004) Science , vol.304 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 18
    • 0037418839 scopus 로고    scopus 로고
    • Bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
    • Brennecke J, Hipfner DR, Stark A, Russell RB, Cohen SM. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 2003; 113: 25-36.
    • (2003) Cell , vol.113 , pp. 25-36
    • Brennecke, J.1    Hipfner, D.R.2    Stark, A.3    Russell, R.B.4    Cohen, S.M.5
  • 19
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • Chen CZ, Li L, Lodish HF, Bartel DP. MicroRNAs modulate hematopoietic lineage differentiation. Science 2004; 303: 83-86.
    • (2004) Science , vol.303 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 22
    • 18144365478 scopus 로고    scopus 로고
    • MicroRNA biogenesis and cancer
    • Gregory RI, Shiekhattar R. MicroRNA biogenesis and cancer. Cancer Res 2005; 65: 3509-3512.
    • (2005) Cancer Res , vol.65 , pp. 3509-3512
    • Gregory, R.I.1    Shiekhattar, R.2
  • 23
    • 0037320941 scopus 로고    scopus 로고
    • Numerous microRNPs in neuronal cells containing novel microRNAs
    • Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G. Numerous microRNPs in neuronal cells containing novel microRNAs. Rna 2003; 9: 180-186.
    • (2003) Rna , vol.9 , pp. 180-186
    • Dostie, J.1    Mourelatos, Z.2    Yang, M.3    Sharma, A.4    Dreyfuss, G.5
  • 25
    • 0345818258 scopus 로고    scopus 로고
    • MicroRNAs and cancer
    • McManus MT. MicroRNAs and cancer. Semin Cancer Biol 2003; 13: 253-258.
    • (2003) Semin Cancer Biol , vol.13 , pp. 253-258
    • McManus, M.T.1
  • 26
    • 16844379687 scopus 로고    scopus 로고
    • The role of small RNAs in human diseases: Potential troublemaker and therapeutic tools
    • Gong H, Liu CM, Liu DP, Liang CC. The role of small RNAs in human diseases: Potential troublemaker and therapeutic tools. Med Res Rev 2005; 25: 361-381.
    • (2005) Med Res Rev , vol.25 , pp. 361-381
    • Gong, H.1    Liu, C.M.2    Liu, D.P.3    Liang, C.C.4
  • 27
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci USA 2004; 101: 2999-3004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3    Hyslop, T.4    Noch, E.5    Yendamuri, S.6
  • 28
    • 18744396337 scopus 로고    scopus 로고
    • Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
    • Calin GA, Dumitru CD, Shimizu M, Bichi R, Zupo S, Noch E et al. Frequent deletions and down-regulation of micro-RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia. Proc Natl Acad Sci USA 2002; 99: 15524-15529.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 15524-15529
    • Calin, G.A.1    Dumitru, C.D.2    Shimizu, M.3    Bichi, R.4    Zupo, S.5    Noch, E.6
  • 29
    • 0032499268 scopus 로고    scopus 로고
    • Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma
    • Stilgenbauer S, Nickolenko J, Wilhelm J, Wolf S, Weitz S, Dohner K et al. Expressed sequences as candidates for a novel tumor suppressor gene at band 13q14 in B-cell chronic lymphocytic leukemia and mantle cell lymphoma. Oncogene 1998; 16: 1891-1897.
    • (1998) Oncogene , vol.16 , pp. 1891-1897
    • Stilgenbauer, S.1    Nickolenko, J.2    Wilhelm, J.3    Wolf, S.4    Weitz, S.5    Dohner, K.6
  • 33
    • 2542626605 scopus 로고    scopus 로고
    • Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative
    • Takamizawa J, Konishi H, Yanagisawa K, Tomida S, Osada H, Endoh H et al. Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004; 64: 3753-3756.
    • (2004) Survival Cancer Res , vol.64 , pp. 3753-3756
    • Takamizawa, J.1    Konishi, H.2    Yanagisawa, K.3    Tomida, S.4    Osada, H.5    Endoh, H.6
  • 34
  • 35
    • 0036229658 scopus 로고    scopus 로고
    • Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis
    • Tam W, Hughes SH, Hayward WS, Besmer P. Avian bic, a gene isolated from a common retroviral site in avian leukosis virus-induced lymphomas that encodes a noncoding RNA, cooperates with c-myc in lymphomagenesis and erythroleukemogenesis. J Virol 2002; 76: 4275-4286.
    • (2002) J Virol , vol.76 , pp. 4275-4286
    • Tam, W.1    Hughes, S.H.2    Hayward, W.S.3    Besmer, P.4
  • 38
    • 17244375710 scopus 로고    scopus 로고
    • Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells
    • Cai X, Lu S, Zhang Z, Gonzalez CM, Damania B, Cullen BR. Kaposi's sarcoma-associated herpesvirus expresses an array of viral microRNAs in latently infected cells. Proc Natl Acad Sci USA 2005; 102: 5570-5575.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 5570-5575
    • Cai, X.1    Lu, S.2    Zhang, Z.3    Gonzalez, C.M.4    Damania, B.5    Cullen, B.R.6
  • 40
    • 14744297918 scopus 로고    scopus 로고
    • Regulation of human immunodeficiency virus 1 transcription by nef microRNA
    • Omoto S, Fujii YR. Regulation of human immunodeficiency virus 1 transcription by nef microRNA. J Gen Virol 2005; 86: 751-755.
    • (2005) J Gen Virol , vol.86 , pp. 751-755
    • Omoto, S.1    Fujii, Y.R.2
  • 41
    • 20444446357 scopus 로고    scopus 로고
    • SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells
    • Sullivan CS, Grundhoff AT, Tevethia S, Pipas JM, Ganem D. SV40-encoded microRNAs regulate viral gene expression and reduce susceptibility to cytotoxic T cells. Nature 2005; 435: 682-686.
    • (2005) Nature , vol.435 , pp. 682-686
    • Sullivan, C.S.1    Grundhoff, A.T.2    Tevethia, S.3    Pipas, J.M.4    Ganem, D.5
  • 43
    • 18044390846 scopus 로고    scopus 로고
    • HIV may produce inhibitory microRNAs (miRNAs) that block production of CD28, CD4 and some interleukins
    • Couturier JP, Root-Bernstein RS. HIV may produce inhibitory microRNAs (miRNAs) that block production of CD28, CD4 and some interleukins. J Theor Biol 2005; 235: 169-184.
    • (2005) J Theor Biol , vol.235 , pp. 169-184
    • Couturier, J.P.1    Root-Bernstein, R.S.2
  • 44
    • 4644223259 scopus 로고    scopus 로고
    • Mechanisms of gene silencing by double-stranded RNA
    • Meister G, Tuschl T. Mechanisms of gene silencing by double-stranded RNA. Nature 2004; 431: 343-349.
    • (2004) Nature , vol.431 , pp. 343-349
    • Meister, G.1    Tuschl, T.2
  • 46
    • 8644247492 scopus 로고    scopus 로고
    • Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis
    • Lu S, Cullen BR. Adenovirus VA1 noncoding RNA can inhibit small interfering RNA and MicroRNA biogenesis. J Virol 2004; 78: 12868-12876.
    • (2004) J Virol , vol.78 , pp. 12868-12876
    • Lu, S.1    Cullen, B.R.2
  • 47
    • 12344306475 scopus 로고    scopus 로고
    • Intramers and aptamers: Applications in protein-function analyses and potential for drug screening
    • Famulok M, Mayer G. Intramers and aptamers: Applications in protein-function analyses and potential for drug screening. Chembiochem 2005; 6: 19-26.
    • (2005) Chembiochem , vol.6 , pp. 19-26
    • Famulok, M.1    Mayer, G.2
  • 48
    • 7944232720 scopus 로고    scopus 로고
    • RNA and microRNAs in fragile X mental retardation
    • Jin P, Alisch RS, Warren ST. RNA and microRNAs in fragile X mental retardation. Nat Cell Biol 2004; 6: 1048-1053.
    • (2004) Nat Cell Biol , vol.6 , pp. 1048-1053
    • Jin, P.1    Alisch, R.S.2    Warren, S.T.3
  • 49
    • 0036792769 scopus 로고    scopus 로고
    • Fragile X-related protein and VIG associate with the RNA interference machinery
    • Caudy AA, Myers M, Hannon GJ, Hammond SM. Fragile X-related protein and VIG associate with the RNA interference machinery. Genes Dev 2002; 16: 2491-2496.
    • (2002) Genes Dev , vol.16 , pp. 2491-2496
    • Caudy, A.A.1    Myers, M.2    Hannon, G.J.3    Hammond, S.M.4
  • 50
    • 0036791671 scopus 로고    scopus 로고
    • A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins
    • Ishizuka A, Siomi MC, Siomi H. A Drosophila fragile X protein interacts with components of RNAi and ribosomal proteins. Genes Dev 2002; 16: 2497-2508.
    • (2002) Genes Dev , vol.16 , pp. 2497-2508
    • Ishizuka, A.1    Siomi, M.C.2    Siomi, H.3
  • 51
    • 1642540373 scopus 로고    scopus 로고
    • Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway
    • Jin P, Zarnescu DC, Ceman S, Nakamoto M, Mowrey J, Jongens TA et al. Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci 2004; 7: 113-117.
    • (2004) Nat Neurosci , vol.7 , pp. 113-117
    • Jin, P.1    Zarnescu, D.C.2    Ceman, S.3    Nakamoto, M.4    Mowrey, J.5    Jongens, T.A.6
  • 54
    • 10344248903 scopus 로고    scopus 로고
    • The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis
    • Landthaler M, Yalcin A, Tuschl T. The human DiGeorge syndrome critical region gene 8 and its D. melanogaster homolog are required for miRNA biogenesis. Curr Biol 2004; 14: 2162-2167.
    • (2004) Curr Biol , vol.14 , pp. 2162-2167
    • Landthaler, M.1    Yalcin, A.2    Tuschl, T.3
  • 55
    • 18844380174 scopus 로고    scopus 로고
    • Polymorphisms in human pre-miRNAs
    • Iwai N, Naraba H. Polymorphisms in human pre-miRNAs. Biochem Biophys Res Commun 2005; 331: 1439-1444.
    • (2005) Biochem Biophys Res Commun , vol.331 , pp. 1439-1444
    • Iwai, N.1    Naraba, H.2
  • 56
    • 0041691111 scopus 로고    scopus 로고
    • MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
    • Zeng Y, Yi R, Cullen BR. MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. Proc Natl Acad Sci USA 2003; 100: 9779-9784.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 9779-9784
    • Zeng, Y.1    Yi, R.2    Cullen, B.R.3
  • 57
    • 1842734241 scopus 로고    scopus 로고
    • Potential applications of siRNA for pain therapy
    • Ganju P, Hall J. Potential applications of siRNA for pain therapy. Expert Opin Biol Ther 2004; 4: 531-542.
    • (2004) Expert Opin Biol Ther , vol.4 , pp. 531-542
    • Ganju, P.1    Hall, J.2
  • 58
    • 20444440706 scopus 로고    scopus 로고
    • Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation
    • Lee YS, Kim HK, Chung S, Kim KS, Dutta A. Depletion of human micro-RNA miR-125b reveals that it is critical for the proliferation of differentiated cells but not for the down-regulation of putative targets during differentiation. J Biol Chem 2005; 280: 16635-16641.
    • (2005) J Biol Chem , vol.280 , pp. 16635-16641
    • Lee, Y.S.1    Kim, H.K.2    Chung, S.3    Kim, K.S.4    Dutta, A.5
  • 59
    • 0345064195 scopus 로고    scopus 로고
    • Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes
    • Boutla A, Delidakis C, Tabler M. Developmental defects by antisense-mediated inactivation of micro-RNAs 2 and 13 in Drosophila and the identification of putative target genes. Nucleic Acids Res 2003; 31: 4973-4980.
    • (2003) Nucleic Acids Res , vol.31 , pp. 4973-4980
    • Boutla, A.1    Delidakis, C.2    Tabler, M.3
  • 61
    • 18844429452 scopus 로고    scopus 로고
    • In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors
    • Devi GR, Beer TM, Corless CL, Arora V, Weller DL, Iversen PL. In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors. Clin Cancer Res 2005; 11: 3930-3938.
    • (2005) Clin Cancer Res , vol.11 , pp. 3930-3938
    • Devi, G.R.1    Beer, T.M.2    Corless, C.L.3    Arora, V.4    Weller, D.L.5    Iversen, P.L.6
  • 62
    • 0034780950 scopus 로고    scopus 로고
    • Drug properties of second-generation antisense oligonucleotides: How do they measure up to their predecessors?
    • Henry SP, Geary RS, Yu R, Levin AA. Drug properties of second-generation antisense oligonucleotides: How do they measure up to their predecessors? Curr Opin Invest Drugs 2001; 2: 1444-1449.
    • (2001) Curr Opin Invest Drugs , vol.2 , pp. 1444-1449
    • Henry, S.P.1    Geary, R.S.2    Yu, R.3    Levin, A.A.4
  • 63
    • 0033579478 scopus 로고    scopus 로고
    • Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides
    • Friedman KJ, Kole J, Cohn JA, Knowles MR, Silverman LM, Kole R. Correction of aberrant splicing of the cystic fibrosis transmembrane conductance regulator (CFTR) gene by antisense oligonucleotides. J Biol Chem 1999; 274: 36193-36199.
    • (1999) J Biol Chem , vol.274 , pp. 36193-36199
    • Friedman, K.J.1    Kole, J.2    Cohn, J.A.3    Knowles, M.R.4    Silverman, L.M.5    Kole, R.6
  • 64
    • 1342289728 scopus 로고    scopus 로고
    • Clinical studies in patients with solid tumors using a second-generation antisense oligonucleotide (GEM 231) targeted against protein kinase A type I
    • Mani S, Goel S, Nesterova M, Martin RM, Grindel JM, Rothenberg ML et al. Clinical studies in patients with solid tumors using a second-generation antisense oligonucleotide (GEM 231) targeted against protein kinase A type I. Ann N Y Acad Sci 2003; 1002: 252-262.
    • (2003) Ann N Y Acad Sci , vol.1002 , pp. 252-262
    • Mani, S.1    Goel, S.2    Nesterova, M.3    Martin, R.M.4    Grindel, J.M.5    Rothenberg, M.L.6
  • 65
    • 14844364472 scopus 로고    scopus 로고
    • Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
    • Cheng AM, Byrom MW, Shelton J, Ford LP. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res 2005; 33: 1290-1297.
    • (2005) Nucleic Acids Res , vol.33 , pp. 1290-1297
    • Cheng, A.M.1    Byrom, M.W.2    Shelton, J.3    Ford, L.P.4
  • 66
    • 0029099305 scopus 로고
    • A New Access to 2-O-Alkylated Ribonucleosides and Properties of 2-O-Alkylated Oligoribonucleotides
    • Martin P. A New Access to 2-O-Alkylated Ribonucleosides and Properties of 2-O-Alkylated Oligoribonucleotides. Helvetica Chim Acta 1995; 78: 486-504.
    • (1995) Helvetica Chim Acta , vol.78 , pp. 486-504
    • Martin, P.1
  • 67
    • 0033916608 scopus 로고    scopus 로고
    • Deletion of individual exons and induction of soluble murine interleukin-5 receptor-alpha chain expression through antisense oligonucleotide-mediated redirection of pre-mRNA splicing
    • Karras JG, McKay RA, Dean NM, Monia BP. Deletion of individual exons and induction of soluble murine interleukin-5 receptor-alpha chain expression through antisense oligonucleotide-mediated redirection of pre-mRNA splicing. Mol Pharmacol 2000; 58: 380-387.
    • (2000) Mol Pharmacol , vol.58 , pp. 380-387
    • Karras, J.G.1    McKay, R.A.2    Dean, N.M.3    Monia, B.P.4
  • 68
    • 0031010177 scopus 로고    scopus 로고
    • 2′-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells
    • Baker BF, Lot SS, Condon TP, Cheng-Flournoy S, Lesnik EA, Sasmor HM et al. 2′-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells. J Biol Chem 1997; 272: 11994-12000.
    • (1997) J Biol Chem , vol.272 , pp. 11994-12000
    • Baker, B.F.1    Lot, S.S.2    Condon, T.P.3    Cheng-Flournoy, S.4    Lesnik, E.A.5    Sasmor, H.M.6
  • 69
    • 20344371233 scopus 로고    scopus 로고
    • Antisense therapy for cancer
    • Gleave ME, Monia BP. Antisense therapy for cancer. Nat Rev Cancer 2005; 5: 468-479.
    • (2005) Nat Rev Cancer , vol.5 , pp. 468-479
    • Gleave, M.E.1    Monia, B.P.2
  • 70
    • 6344277190 scopus 로고    scopus 로고
    • LNA (locked nucleic acid): High-affinity targeting of complementary RNA and DNA
    • Vester B, Wengel J. LNA (locked nucleic acid): High-affinity targeting of complementary RNA and DNA. Biochemistry 2004; 43: 13233-13241.
    • (2004) Biochemistry , vol.43 , pp. 13233-13241
    • Vester, B.1    Wengel, J.2
  • 71
    • 0037143606 scopus 로고    scopus 로고
    • Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing
    • Childs JL, Disney MD, Turner DH. Oligonucleotide directed misfolding of RNA inhibits Candida albicans group I intron splicing. Proc Natl Acad Sci USA 2002; 99: 11091-11096.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 11091-11096
    • Childs, J.L.1    Disney, M.D.2    Turner, D.H.3
  • 72
    • 0037031288 scopus 로고    scopus 로고
    • Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase
    • Elayadi AN, Braasch DA, Corey DR. Implications of high-affinity hybridization by locked nucleic acid oligomers for inhibition of human telomerase. Biochemistry 2002; 41: 9973-9981.
    • (2002) Biochemistry , vol.41 , pp. 9973-9981
    • Elayadi, A.N.1    Braasch, D.A.2    Corey, D.R.3
  • 74
    • 0037326836 scopus 로고    scopus 로고
    • In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides
    • Fluiter K, ten Asbroek AL, de Wissel MB, Jakobs ME, Wissenbach M, Olsson H et al. In vivo tumor growth inhibition and biodistribution studies of locked nucleic acid (LNA) antisense oligonucleotides. Nucleic Acids Res 2003; 31: 953-962.
    • (2003) Nucleic Acids Res , vol.31 , pp. 953-962
    • Fluiter, K.1    ten Asbroek, A.L.2    de Wissel, M.B.3    Jakobs, M.E.4    Wissenbach, M.5    Olsson, H.6
  • 75
    • 16544365954 scopus 로고    scopus 로고
    • Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes
    • Valoczi A, Hornyik C, Varga N, Burgyan J, Kauppinen S, Havelda Z. Sensitive and specific detection of microRNAs by northern blot analysis using LNA-modified oligonucleotide probes. Nucleic Acids Res 2004; 32: e175.
    • (2004) Nucleic Acids Res , vol.32
    • Valoczi, A.1    Hornyik, C.2    Varga, N.3    Burgyan, J.4    Kauppinen, S.5    Havelda, Z.6
  • 76
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res 2005; 65: 6029-6033.
    • (2005) Cancer Res , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 77
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, Castle J et al. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005; 433: 769-773.
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3    Grimson, A.4    Schelter, J.M.5    Castle, J.6
  • 78
    • 15244354492 scopus 로고    scopus 로고
    • Incorporating structure to predict microRNA targets
    • Robins H, Li Y, Padgett RW. Incorporating structure to predict microRNA targets. Proc Natl Acad Sci USA 2005; 102: 4006-4009.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4006-4009
    • Robins, H.1    Li, Y.2    Padgett, R.W.3
  • 81
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 2005; 120: 15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 82
    • 18744390776 scopus 로고    scopus 로고
    • The age of high-throughput microRNA profiling
    • Esquela-Kerscher A, Slack FJ. The age of high-throughput microRNA profiling. Nat Methods 2004; 1: 106-107.
    • (2004) Nat Methods , vol.1 , pp. 106-107
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 84
    • 13544263358 scopus 로고    scopus 로고
    • Silence is golden: Can RNA interference therapeutics deliver?
    • Beal J. Silence is golden: Can RNA interference therapeutics deliver? Drug Discov Today 2005; 10: 169-172.
    • (2005) Drug Discov Today , vol.10 , pp. 169-172
    • Beal, J.1
  • 85
    • 11844251207 scopus 로고    scopus 로고
    • RNA interference in vivo: Toward synthetic small inhibitory RNA-based therapeutics
    • de Fougerolles A, Manoharan M, Meyers R, Vornlocher HP. RNA interference in vivo: Toward synthetic small inhibitory RNA-based therapeutics. Methods Enzymol 2005; 392: 278-296.
    • (2005) Methods Enzymol , vol.392 , pp. 278-296
    • de Fougerolles, A.1    Manoharan, M.2    Meyers, R.3    Vornlocher, H.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.