-
1
-
-
33746617272
-
Hematopoietic stem cells: The paradigmatic tissue-specific stem cell
-
Bryder D, Rossi DJ, Weissman IL. Hematopoietic stem cells: the paradigmatic tissue-specific stem cell. Am J Pathol. 2006;169(2):338-346.
-
(2006)
Am J Pathol.
, vol.169
, Issue.2
, pp. 338-346
-
-
Bryder, D.1
Rossi, D.J.2
Weissman, I.L.3
-
2
-
-
84862532139
-
Hematopoietic stem cell heterogeneity takes center stage
-
Copley MR, Beer PA, Eaves CJ. Hematopoietic stem cell heterogeneity takes center stage. Cell Stem Cell. 2012;10(6):690-697.
-
(2012)
Cell Stem Cell.
, vol.10
, Issue.6
, pp. 690-697
-
-
Copley, M.R.1
Beer, P.A.2
Eaves, C.J.3
-
3
-
-
84868374023
-
The transcriptional landscape of hematopoietic stem cell ontogeny
-
McKinney-Freeman S, Cahan P, Li H, et al. The transcriptional landscape of hematopoietic stem cell ontogeny. Cell Stem Cell. 2012;11(5): 701-714.
-
(2012)
Cell Stem Cell.
, vol.11
, Issue.5
, pp. 701-714
-
-
McKinney-Freeman, S.1
Cahan, P.2
Li, H.3
-
4
-
-
20044363097
-
Gene expression profile of murine long-term reconstituting vs. Short-term reconstituting hematopoietic stem cells
-
Zhong JF, Zhao Y, Sutton S, et al. Gene expression profile of murine long-term reconstituting vs. short-term reconstituting hematopoietic stem cells. Proc Natl Acad Sci USA. 2005;102(7):2448-2453.
-
(2005)
Proc Natl Acad Sci USA.
, vol.102
, Issue.7
, pp. 2448-2453
-
-
Zhong, J.F.1
Zhao, Y.2
Sutton, S.3
-
5
-
-
61849137222
-
Many roads to maturity: MicroRNA biogenesis pathways and their regulation
-
Winter J, Jung S, Keller S, Gregory RI, Diederichs S. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol. 2009; 11(3):228-234.
-
(2009)
Nat Cell Biol.
, vol.11
, Issue.3
, pp. 228-234
-
-
Winter, J.1
Jung, S.2
Keller, S.3
Gregory, R.I.4
Diederichs, S.5
-
6
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel DP. MicroRNAs: target recognition and regulatory functions. Cell. 2009;136(2):215-233.
-
(2009)
Cell.
, vol.136
, Issue.2
, pp. 215-233
-
-
Bartel, D.P.1
-
7
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman RC, Farh KK-H, Burge CB, Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009;19(1):92-105.
-
(2009)
Genome Res.
, vol.19
, Issue.1
, pp. 92-105
-
-
Friedman, R.C.1
Kk-H, F.2
Burge, C.B.3
Bartel, D.P.4
-
8
-
-
79955570371
-
MicroRNA programs in normal and aberrant stem and progenitor cells
-
Arnold CP, Tan R, Zhou B, et al. MicroRNA programs in normal and aberrant stem and progenitor cells. Genome Res. 2011;21(5): 798-810.
-
(2011)
Genome Res.
, vol.21
, Issue.5
, pp. 798-810
-
-
Arnold, C.P.1
Tan, R.2
Zhou, B.3
-
9
-
-
77949518018
-
MicroRNA- 29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia
-
Han Y-C, Park CY, Bhagat G, et al. microRNA- 29a induces aberrant self-renewal capacity in hematopoietic progenitors, biased myeloid development, and acute myeloid leukemia. J Exp Med. 2010;207(3):475-489.
-
(2010)
J Exp Med.
, vol.207
, Issue.3
, pp. 475-489
-
-
Han, Y.-C.1
Park, C.Y.2
Bhagat, G.3
-
10
-
-
77957252821
-
Comprehensive microRNA expression profiling of the hematopoietic hierarchy
-
Petriv OI, Kuchenbauer F, Delaney AD, et al. Comprehensive microRNA expression profiling of the hematopoietic hierarchy. Proc Natl Acad Sci USA. 2010;107(35):15443-15448.
-
(2010)
Proc Natl Acad Sci USA.
, vol.107
, Issue.35
, pp. 15443-15448
-
-
Petriv, O.I.1
Kuchenbauer, F.2
Delaney, A.D.3
-
11
-
-
78751557893
-
Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations
-
Starczynowski DT, Morin R, McPherson A, et al. Genome-wide identification of human microRNAs located in leukemia-associated genomic alterations. Blood. 2011;117(2):595-607.
-
(2011)
Blood.
, vol.117
, Issue.2
, pp. 595-607
-
-
Starczynowski, D.T.1
Morin, R.2
McPherson, A.3
-
12
-
-
77956270732
-
MicroRNA miR- 125a controls hematopoietic stem cell number
-
Guo S, Lu J, Schlanger R, et al. MicroRNA miR- 125a controls hematopoietic stem cell number. Proc Natl Acad Sci USA. 2010;107(32): 14229-14234.
-
(2010)
Proc Natl Acad Sci USA.
, vol.107
, Issue.32
, pp. 14229-14234
-
-
Guo, S.1
Lu, J.2
Schlanger, R.3
-
13
-
-
84898887673
-
MiR- 99a/100;125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFb and Wnt signaling
-
Emmrich S, Rasche M, Schöning J, et al. miR- 99a/100;125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFb and Wnt signaling. Genes Dev. 2014;28(8):858-874.
-
(2014)
Genes Dev.
, vol.28
, Issue.8
, pp. 858-874
-
-
Emmrich, S.1
Rasche, M.2
Schöning, J.3
-
14
-
-
78650722292
-
MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets
-
Ooi AGL, Sahoo D, Adorno M, Wang Y, Weissman IL, Park CY. MicroRNA-125b expands hematopoietic stem cells and enriches for the lymphoid-balanced and lymphoid-biased subsets. Proc Natl Acad Sci USA. 2010;107(50): 21505-21510.
-
(2010)
Proc Natl Acad Sci USA.
, vol.107
, Issue.50
, pp. 21505-21510
-
-
Ooi, A.G.L.1
Sahoo, D.2
Adorno, M.3
Wang, Y.4
Weissman, I.L.5
Park, C.Y.6
-
15
-
-
84870894496
-
Attenuation of miR-126 activity expands HSC in vivo without exhaustion
-
Lechman ER, Gentner B, van Galen P, et al. Attenuation of miR-126 activity expands HSC in vivo without exhaustion. Cell Stem Cell. 2012; 11(6):799-811.
-
(2012)
Cell Stem Cell.
, vol.11
, Issue.6
, pp. 799-811
-
-
Lechman, E.R.1
Gentner, B.2
Van Galen, P.3
-
16
-
-
84879060116
-
MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice
-
Zhao JL, Rao DS, O'Connell RM, Garcia-Flores Y, Baltimore D. MicroRNA-146a acts as a guardian of the quality and longevity of hematopoietic stem cells in mice. eLife. 2013;2: e00537.
-
(2013)
ELife.
, vol.2
, pp. e00537
-
-
Zhao, J.L.1
Rao, D.S.2
O'Connell, R.M.3
Garcia-Flores, Y.4
Baltimore, D.5
-
17
-
-
84867883259
-
MicroRNA-29 in the adaptive immune system: Setting the threshold
-
Liston A, Papadopoulou AS, Danso-Abeam D, Dooley J. MicroRNA-29 in the adaptive immune system: setting the threshold. Cell Mol Life Sci. 2012;69(21):3533-3541.
-
(2012)
Cell Mol Life Sci.
, vol.69
, Issue.21
, pp. 3533-3541
-
-
Liston, A.1
Papadopoulou, A.S.2
Danso-Abeam, D.3
Dooley, J.4
-
18
-
-
80052033649
-
The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-g
-
Ma F, Xu S, Liu X, et al. The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-g. Nat Immunol. 2011;12(9):861-869.
-
(2011)
Nat Immunol.
, vol.12
, Issue.9
, pp. 861-869
-
-
Ma, F.1
Xu, S.2
Liu, X.3
-
19
-
-
84855931651
-
The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-A receptor
-
Papadopoulou AS, Dooley J, Linterman MA, et al. The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-a receptor. Nat Immunol. 2012;13(2): 181-187.
-
(2012)
Nat Immunol.
, vol.13
, Issue.2
, pp. 181-187
-
-
Papadopoulou, A.S.1
Dooley, J.2
Linterman, M.A.3
-
20
-
-
84872038076
-
MicroRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming
-
Guo X, Liu Q, Wang G, et al. microRNA-29b is a novel mediator of Sox2 function in the regulation of somatic cell reprogramming. Cell Res. 2013; 23(1):142-156.
-
(2013)
Cell Res.
, vol.23
, Issue.1
, pp. 142-156
-
-
Guo, X.1
Liu, Q.2
Wang, G.3
-
21
-
-
77954647669
-
The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML
-
Eyholzer M, Schmid S, Wilkens L, Mueller BU, Pabst T. The tumour-suppressive miR-29a/b1 cluster is regulated by CEBPA and blocked in human AML. Br J Cancer. 2010;103(2):275-284.
-
(2010)
Br J Cancer.
, vol.103
, Issue.2
, pp. 275-284
-
-
Eyholzer, M.1
Schmid, S.2
Wilkens, L.3
Mueller, B.U.4
Pabst, T.5
-
22
-
-
63349102720
-
In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood
-
Park CY, Majeti R, Weissman IL. In vivo evaluation of human hematopoiesis through xenotransplantation of purified hematopoietic stem cells from umbilical cord blood. Nat Protoc. 2008;3(12):1932-1940.
-
(2008)
Nat Protoc.
, vol.3
, Issue.12
, pp. 1932-1940
-
-
Park, C.Y.1
Majeti, R.2
Weissman, I.L.3
-
23
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell. 2005;120(1):15-20.
-
(2005)
Cell.
, vol.120
, Issue.1
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
25
-
-
0034624828
-
A clonogenic common myeloid progenitor that gives rise to all myeloid lineages
-
Akashi K, Traver D, Miyamoto T, Weissman IL. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages. Nature. 2000; 404(6774):193-197.
-
(2000)
Nature.
, vol.404
, Issue.6774
, pp. 193-197
-
-
Akashi, K.1
Traver, D.2
Miyamoto, T.3
Weissman, I.L.4
-
26
-
-
77950418688
-
Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion
-
Beerman I, Bhattacharya D, Zandi S, et al. Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion. Proc Natl Acad Sci USA. 2010;107(12):5465-5470.
-
(2010)
Proc Natl Acad Sci USA.
, vol.107
, Issue.12
, pp. 5465-5470
-
-
Beerman, I.1
Bhattacharya, D.2
Zandi, S.3
-
27
-
-
84857873445
-
Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs
-
Benz C, Copley MR, Kent DG, et al. Hematopoietic stem cell subtypes expand differentially during development and display distinct lymphopoietic programs. Cell Stem Cell. 2012;10(3):273-283.
-
(2012)
Cell Stem Cell.
, vol.10
, Issue.3
, pp. 273-283
-
-
Benz, C.1
Copley, M.R.2
Kent, D.G.3
-
28
-
-
0030831130
-
Identification of clonogenic common lymphoid progenitors in mouse bone marrow
-
Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell. 1997;91(5):661-672.
-
(1997)
Cell.
, vol.91
, Issue.5
, pp. 661-672
-
-
Kondo, M.1
Weissman, I.L.2
Akashi, K.3
-
29
-
-
38349132624
-
Deconstructing stem cell self-renewal: Genetic insights into cell-cycle regulation
-
Orford KW, Scadden DT. Deconstructing stem cell self-renewal: genetic insights into cell-cycle regulation. Nat Rev Genet. 2008;9(2):115-128.
-
(2008)
Nat Rev Genet.
, vol.9
, Issue.2
, pp. 115-128
-
-
Orford, K.W.1
Scadden, D.T.2
-
30
-
-
80052266532
-
MicroRNAs can generate thresholds in target gene expression
-
Mukherji S, Ebert MS, Zheng GXY, Tsang JS, Sharp PA, van Oudenaarden A. MicroRNAs can generate thresholds in target gene expression. Nat Genet. 2011;43(9):854-859.
-
(2011)
Nat Genet.
, vol.43
, Issue.9
, pp. 854-859
-
-
Mukherji, S.1
Ebert, M.S.2
Zheng, G.X.Y.3
Tsang, J.S.4
Sharp, P.A.5
Van Oudenaarden, A.6
-
31
-
-
79958135926
-
Molecular signatures database (MSigDB) 3.0
-
Liberzon A, Subramanian A, Pinchback R, Thorvaldsdóttir H, Tamayo P, Mesirov JP. Molecular signatures database (MSigDB) 3.0. Bioinformatics. 2011;27(12):1739-1740.
-
(2011)
Bioinformatics.
, vol.27
, Issue.12
, pp. 1739-1740
-
-
Liberzon, A.1
Subramanian, A.2
Pinchback, R.3
Thorvaldsdóttir, H.4
Tamayo, P.5
Mesirov, J.P.6
-
32
-
-
67650588646
-
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1
-
Garzon R, Liu S, Fabbri M, et al. MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1. Blood. 2009;113(25): 6411-6418.
-
(2009)
Blood.
, vol.113
, Issue.25
, pp. 6411-6418
-
-
Garzon, R.1
Liu, S.2
Fabbri, M.3
-
33
-
-
35649020283
-
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
-
Fabbri M, Garzon R, Cimmino A, et al. MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. Proc Natl Acad Sci USA. 2007;104(40): 15805-15810.
-
(2007)
Proc Natl Acad Sci USA.
, vol.104
, Issue.40
, pp. 15805-15810
-
-
Fabbri, M.1
Garzon, R.2
Cimmino, A.3
-
34
-
-
84555207349
-
Dnmt3a is essential for hematopoietic stem cell differentiation
-
Challen GA, Sun D, Jeong M, et al. Dnmt3a is essential for hematopoietic stem cell differentiation. Nat Genet. 2012;44(1):23-31.
-
(2012)
Nat Genet.
, vol.44
, Issue.1
, pp. 23-31
-
-
Challen, G.A.1
Sun, D.2
Jeong, M.3
-
35
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
Ley TJ, Ding L, Walter MJ, et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med. 2010;363(25):2424-2433.
-
(2010)
N Engl J Med.
, vol.363
, Issue.25
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
-
36
-
-
79953176952
-
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
-
Yan X-J, Xu J, Gu Z-H, et al. Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet. 2011;43(4): 309-315.
-
(2011)
Nat Genet.
, vol.43
, Issue.4
, pp. 309-315
-
-
Yan, X.-J.1
Xu, J.2
Gu, Z.-H.3
-
37
-
-
84863393263
-
Prognostic relevance of integrated genetic profiling in acute myeloid leukemia
-
Patel JP, Gönen M, Figueroa ME, et al. Prognostic relevance of integrated genetic profiling in acute myeloid leukemia. N Engl J Med. 2012;366(12):1079-1089.
-
(2012)
N Engl J Med.
, vol.366
, Issue.12
, pp. 1079-1089
-
-
Patel, J.P.1
Gönen, M.2
Figueroa, M.E.3
-
38
-
-
33846699083
-
A hexanucleotide element directs microRNA nuclear import
-
Hwang H-W, Wentzel EA, Mendell JT. A hexanucleotide element directs microRNA nuclear import. Science. 2007;315(5808):97-100.
-
(2007)
Science.
, vol.315
, Issue.5808
, pp. 97-100
-
-
Hwang, H.-W.1
Wentzel, E.A.2
Mendell, J.T.3
-
39
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
Trowbridge JJ, Snow JW, Kim J, Orkin SH. DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell. 2009;5(4):442-449.
-
(2009)
Cell Stem Cell.
, vol.5
, Issue.4
, pp. 442-449
-
-
Trowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
40
-
-
77951003346
-
MicroRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma
-
Zhao J-J, Lin J, Lwin T, et al. microRNA expression profile and identification of miR-29 as a prognostic marker and pathogenetic factor by targeting CDK6 in mantle cell lymphoma. Blood. 2010;115(13):2630-2639.
-
(2010)
Blood.
, vol.115
, Issue.13
, pp. 2630-2639
-
-
Zhao, J.-J.1
Lin, J.2
Lwin, T.3
-
41
-
-
33846190181
-
Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181
-
Pekarsky Y, Santanam U, Cimmino A, et al. Tcl1 expression in chronic lymphocytic leukemia is regulated by miR-29 and miR-181. Cancer Res. 2006;66(24):11590-11593.
-
(2006)
Cancer Res.
, vol.66
, Issue.24
, pp. 11590-11593
-
-
Pekarsky, Y.1
Santanam, U.2
Cimmino, A.3
-
42
-
-
84855885803
-
Cell cycle regulation in hematopoietic stem cells
-
Pietras EM, Warr MR, Passegué E. Cell cycle regulation in hematopoietic stem cells. J Cell Biol. 2011;195(5):709-720.
-
(2011)
J Cell Biol.
, vol.195
, Issue.5
, pp. 709-720
-
-
Pietras, E.M.1
Warr, M.R.2
Passegué, E.3
-
43
-
-
73949118737
-
MicroRNA 29b functions in acute myeloid leukemia
-
Garzon R, Heaphy CEA, Havelange V, et al. MicroRNA 29b functions in acute myeloid leukemia. Blood. 2009;114(26):5331-5341.
-
(2009)
Blood.
, vol.114
, Issue.26
, pp. 5331-5341
-
-
Garzon, R.1
Heaphy, C.E.A.2
Havelange, V.3
-
44
-
-
84894304555
-
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission
-
Corces-Zimmerman MR, Hong WJ, Weissman IL, Medeiros BC, Majeti R. Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. Proc Natl Acad Sci USA. 2014;111(7):2548-2553.
-
(2014)
Proc Natl Acad Sci USA.
, vol.111
, Issue.7
, pp. 2548-2553
-
-
Corces-Zimmerman, M.R.1
Hong, W.J.2
Weissman, I.L.3
Medeiros, B.C.4
Majeti, R.5
-
45
-
-
84865827060
-
Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia
-
Jan M, Snyder TM, Corces-Zimmerman MR, et al. Clonal evolution of preleukemic hematopoietic stem cells precedes human acute myeloid leukemia. Sci Transl Med. 2012;4(149):149ra118.
-
(2012)
Sci Transl Med.
, vol.4
, Issue.149
, pp. 149ra118
-
-
Jan, M.1
Snyder, T.M.2
Corces-Zimmerman, M.R.3
-
46
-
-
84894245627
-
Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
-
HALT Pan- Leukemia Gene Panel Consortium
-
Shlush LI, Zandi S, Mitchell A, et al; HALT Pan- Leukemia Gene Panel Consortium. Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia. Nature. 2014;506(7488): 328-333.
-
(2014)
Nature.
, vol.506
, Issue.7488
, pp. 328-333
-
-
Shlush, L.I.1
Zandi, S.2
Mitchell, A.3
|