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Volumn 449, Issue 7163, 2007, Pages 682-688

Tumour invasion and metastasis initiated by microRNA-10b in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; MICRORNA; PROTEIN D10; TRANSCRIPTION FACTOR TWIST; UNCLASSIFIED DRUG;

EID: 35148886434     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature06174     Document Type: Article
Times cited : (2326)

References (48)
  • 1
    • 0038481970 scopus 로고    scopus 로고
    • The pathogenesis of cancer metastasis: The 'seed and soil' hypothesis revisited
    • Fidler, I. J. The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisited. Nature Rev. Cancer 3, 453-458 (2003).
    • (2003) Nature Rev. Cancer , vol.3 , pp. 453-458
    • Fidler, I.J.1
  • 2
    • 0033789680 scopus 로고    scopus 로고
    • The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells
    • Batlle, E. et al. The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells. Nature Cell Biol. 2, 84-89 (2000).
    • (2000) Nature Cell Biol , vol.2 , pp. 84-89
    • Batlle, E.1
  • 3
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • Cano, A. et al. The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nature Cell Biol. 2, 76-83 (2000).
    • (2000) Nature Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1
  • 4
    • 0034964418 scopus 로고    scopus 로고
    • The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion
    • Comijn, J. et al. The two-handed E box binding zinc finger protein SIP1 downregulates E-cadherin and induces invasion. Mol. Cell 7, 1267-1278 (2001).
    • (2001) Mol. Cell , vol.7 , pp. 1267-1278
    • Comijn, J.1
  • 5
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: A comparison with Snail and E47 repressors
    • Bolos, V. et al. The transcription factor Slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J. Cell Sci. 116, 499-511 (2003).
    • (2003) J. Cell Sci , vol.116 , pp. 499-511
    • Bolos, V.1
  • 6
    • 2942707848 scopus 로고    scopus 로고
    • Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis
    • Yang, J. et al. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell 117, 927-939 (2004).
    • (2004) Cell , vol.117 , pp. 927-939
    • Yang, J.1
  • 7
    • 34250840412 scopus 로고    scopus 로고
    • The Spemann organizer gene, Goosecoid, promotes tumor metastasis
    • Hartwell, K. A. et al. The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Proc. Natl Acad. Sci. USA 103, 18969-18974 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 18969-18974
    • Hartwell, K.A.1
  • 8
    • 34547141894 scopus 로고    scopus 로고
    • Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers
    • Mani, S. A. et al. Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proc. Natl Acad. Sci. USA 104, 10069-10074 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 10069-10074
    • Mani, S.A.1
  • 9
    • 33750370444 scopus 로고    scopus 로고
    • MicroRNA signatures in human cancers
    • Calin, G. A. & Croce, C. M. MicroRNA signatures in human cancers. Nature Rev. Cancer 6, 857-866 (2006).
    • (2006) Nature Rev. Cancer , vol.6 , pp. 857-866
    • Calin, G.A.1    Croce, C.M.2
  • 10
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs - microRNAs with a role in cancer
    • Esquela-Kerscher, A. & Slack, F. J. Oncomirs - microRNAs with a role in cancer. Nature Rev. Cancer 6, 259-269 (2006).
    • (2006) Nature Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 11
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel, D. P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116, 281-297 (2004).
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 12
    • 0037418839 scopus 로고    scopus 로고
    • bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila
    • Brennecke, J., Hipfner, D. R., Stark, A., Russell, R. B. & Cohen, S. M. bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila. Cell 113, 25-36 (2003).
    • (2003) Cell , vol.113 , pp. 25-36
    • Brennecke, J.1    Hipfner, D.R.2    Stark, A.3    Russell, R.B.4    Cohen, S.M.5
  • 13
    • 0346727524 scopus 로고    scopus 로고
    • MicroRNAs modulate hematopoietic lineage differentiation
    • Chen, C. Z., Li, L., Lodish, H. F. & Bartel, D. P. MicroRNAs modulate hematopoietic lineage differentiation. Science 303, 83-86 (2004).
    • (2004) Science , vol.303 , pp. 83-86
    • Chen, C.Z.1    Li, L.2    Lodish, H.F.3    Bartel, D.P.4
  • 14
    • 9144270691 scopus 로고    scopus 로고
    • A pancreatic islet-specific microRNA regulates insulin secretion
    • Poy, M. N. et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature 432, 226-230 (2004).
    • (2004) Nature , vol.432 , pp. 226-230
    • Poy, M.N.1
  • 15
    • 33644619021 scopus 로고    scopus 로고
    • Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs
    • Yi, R. et al. Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nature Genet. 38, 356-362 (2006).
    • (2006) Nature Genet , vol.38 , pp. 356-362
    • Yi, R.1
  • 16
    • 31144479591 scopus 로고    scopus 로고
    • A brain-specific microRNA regulates dendritic spine development
    • Schratt, G. M. et al. A brain-specific microRNA regulates dendritic spine development. Nature 439, 283-289 (2006).
    • (2006) Nature , vol.439 , pp. 283-289
    • Schratt, G.M.1
  • 17
    • 12144290519 scopus 로고    scopus 로고
    • Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin, G. A. et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. Proc. Natl Acad. Sci. USA 101, 2999-3004 (2004).
    • (2004) Proc. Natl Acad. Sci. USA , vol.101 , pp. 2999-3004
    • Calin, G.A.1
  • 18
    • 20444467290 scopus 로고    scopus 로고
    • A microRNA polycistron as a potential human oncogene
    • He, L. et al. A microRNA polycistron as a potential human oncogene. Nature 435, 828-833 (2005).
    • (2005) Nature , vol.435 , pp. 828-833
    • He, L.1
  • 19
    • 20044395613 scopus 로고    scopus 로고
    • RAS is regulated by the let-7 microRNA family
    • Johnson, S. M. et al. RAS is regulated by the let-7 microRNA family. Cell 120, 635-647 (2005).
    • (2005) Cell , vol.120 , pp. 635-647
    • Johnson, S.M.1
  • 20
    • 20444460289 scopus 로고    scopus 로고
    • MicroRNA expression profiles classify human cancers
    • Lu, J. et al. MicroRNA expression profiles classify human cancers. Nature 435, 834-838 (2005).
    • (2005) Nature , vol.435 , pp. 834-838
    • Lu, J.1
  • 21
    • 33750600178 scopus 로고    scopus 로고
    • MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior
    • Roldo, C. et al. MicroRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J. Clin. Oncol. 24, 4677-4684 (2006).
    • (2006) J. Clin. Oncol , vol.24 , pp. 4677-4684
    • Roldo, C.1
  • 22
    • 23844555119 scopus 로고    scopus 로고
    • MicroRNA gene expression deregulation in human breast cancer
    • Iorio, M. V. et al. MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 65, 7065-7070 (2005).
    • (2005) Cancer Res , vol.65 , pp. 7065-7070
    • Iorio, M.V.1
  • 23
    • 1242318826 scopus 로고    scopus 로고
    • Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
    • Meister, G., Landthaler, M., Dorsett, Y. & Tuschl, T. Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA 10, 544-550 (2004).
    • (2004) RNA , vol.10 , pp. 544-550
    • Meister, G.1    Landthaler, M.2    Dorsett, Y.3    Tuschl, T.4
  • 24
    • 14844364472 scopus 로고    scopus 로고
    • Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
    • Cheng, A. M., Byrom, M. W., Shelton, J. & Ford, L. P. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res. 33, 1290-1297 (2005).
    • (2005) Nucleic Acids Res , vol.33 , pp. 1290-1297
    • Cheng, A.M.1    Byrom, M.W.2    Shelton, J.3    Ford, L.P.4
  • 25
    • 0035177216 scopus 로고    scopus 로고
    • Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
    • Elenbaas, B. et al. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes Dev. 15, 50-65 (2001).
    • (2001) Genes Dev , vol.15 , pp. 50-65
    • Elenbaas, B.1
  • 26
    • 0027510686 scopus 로고
    • Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media
    • Ethier, S. P., Mahacek, M. L., Gullick, W. J., Frank, T. S. & Weber, B. L. Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media. Cancer Res. 53, 627-635 (1993).
    • (1993) Cancer Res , vol.53 , pp. 627-635
    • Ethier, S.P.1    Mahacek, M.L.2    Gullick, W.J.3    Frank, T.S.4    Weber, B.L.5
  • 27
    • 22244455403 scopus 로고    scopus 로고
    • A mouse model of human breast cancer metastasis to human bone
    • Kuperwasser, C. et al. A mouse model of human breast cancer metastasis to human bone. Cancer Res. 65, 6130-6138 (2005).
    • (2005) Cancer Res , vol.65 , pp. 6130-6138
    • Kuperwasser, C.1
  • 28
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • Thiery, J. P. Epithelial-mesenchymal transitions in tumour progression. Nature Rev. Cancer 2, 442-454 (2002).
    • (2002) Nature Rev. Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 29
    • 0032006641 scopus 로고    scopus 로고
    • The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis
    • Cripps, R. M. et al. The myogenic regulatory gene Mef2 is a direct target for transcriptional activation by Twist during Drosophila myogenesis. Genes Dev. 12, 422-434 (1998).
    • (1998) Genes Dev , vol.12 , pp. 422-434
    • Cripps, R.M.1
  • 30
    • 33947192053 scopus 로고    scopus 로고
    • Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel
    • Cheng, G. Z. et al. Twist transcriptionally up-regulates AKT2 in breast cancer cells leading to increased migration, invasion, and resistance to paclitaxel. Cancer Res. 67, 1979-1987 (2007).
    • (2007) Cancer Res , vol.67 , pp. 1979-1987
    • Cheng, G.Z.1
  • 31
    • 34047234690 scopus 로고    scopus 로고
    • Characterization and identification of microRNA core promoters in four model species
    • Zhou, X., Ruan, J., Wang, G. & Zhang, W. Characterization and identification of microRNA core promoters in four model species. PLoS Comput. Biol. 3, e37 (2007).
    • (2007) PLoS Comput. Biol , vol.3
    • Zhou, X.1    Ruan, J.2    Wang, G.3    Zhang, W.4
  • 33
    • 20944450160 scopus 로고    scopus 로고
    • Combinatorial microRNA target predictions
    • Krek, A. et al. Combinatorial microRNA target predictions. Nature Genet. 37, 495-500 (2005).
    • (2005) Nature Genet , vol.37 , pp. 495-500
    • Krek, A.1
  • 34
    • 23844473412 scopus 로고    scopus 로고
    • Aberrant expression of HOX genes in human invasive breast carcinoma
    • Makiyama, K. et al. Aberrant expression of HOX genes in human invasive breast carcinoma. Oncol. Rep. 13, 673-679 (2005).
    • (2005) Oncol. Rep , vol.13 , pp. 673-679
    • Makiyama, K.1
  • 35
    • 23844537411 scopus 로고    scopus 로고
    • Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model
    • Carrio, M., Arderiu, G., Myers, C. & Boudreau, N. J. Homeobox D10 induces phenotypic reversion of breast tumor cells in a three-dimensional culture model. Cancer Res. 65, 7177-7185 (2005).
    • (2005) Cancer Res , vol.65 , pp. 7177-7185
    • Carrio, M.1    Arderiu, G.2    Myers, C.3    Boudreau, N.J.4
  • 36
    • 0036899023 scopus 로고    scopus 로고
    • Sustained expression of homeobox D10 inhibits angiogenesis
    • Myers, C., Charboneau, A., Cheung, I., Hanks, D. & Boudreau, N. Sustained expression of homeobox D10 inhibits angiogenesis. Am. J. Pathol. 161, 2099-2109 (2002).
    • (2002) Am. J. Pathol , vol.161 , pp. 2099-2109
    • Myers, C.1    Charboneau, A.2    Cheung, I.3    Hanks, D.4    Boudreau, N.5
  • 37
    • 0034601487 scopus 로고    scopus 로고
    • Genomic analysis of metastasis reveals an essential role for RhoC
    • Clark, E. A., Golub, T. R., Lander, E. S. & Hynes, R. O. Genomic analysis of metastasis reveals an essential role for RhoC. Nature 406, 532-535 (2000).
    • (2000) Nature , vol.406 , pp. 532-535
    • Clark, E.A.1    Golub, T.R.2    Lander, E.S.3    Hynes, R.O.4
  • 38
    • 24344486013 scopus 로고    scopus 로고
    • RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis
    • Hakem, A. et al. RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis. Genes Dev. 19, 1974-1979 (2005).
    • (2005) Genes Dev , vol.19 , pp. 1974-1979
    • Hakem, A.1
  • 39
    • 33748038365 scopus 로고    scopus 로고
    • RhoC GTPase expression as a potential marker of lymph node metastasis in squamous cell carcinomas of the head and neck
    • Kleer, C. G. et al. RhoC GTPase expression as a potential marker of lymph node metastasis in squamous cell carcinomas of the head and neck. Clin. Cancer Res. 12, 4485-4490 (2006).
    • (2006) Clin. Cancer Res , vol.12 , pp. 4485-4490
    • Kleer, C.G.1
  • 40
    • 0141889574 scopus 로고    scopus 로고
    • Expression of RhoC is associated with metastasis of gastric carcinomas
    • Kondo, T. et al. Expression of RhoC is associated with metastasis of gastric carcinomas. Pathobiology 71, 19-25 (2004).
    • (2004) Pathobiology , vol.71 , pp. 19-25
    • Kondo, T.1
  • 41
    • 16644374595 scopus 로고    scopus 로고
    • Wang, W. et al. Overexpression of the RhoC gene correlates with invasion and metastasis of hepatocellular carcinoma Chinese J. Oncol. (Zhonghua Zhong Liu Za Zhi.), 26, 279-282 (2004).
    • Wang, W. et al. Overexpression of the RhoC gene correlates with invasion and metastasis of hepatocellular carcinoma Chinese J. Oncol. (Zhonghua Zhong Liu Za Zhi.), 26, 279-282 (2004).
  • 42
    • 0027092936 scopus 로고
    • Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion
    • Reichmann, E. et al. Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion. Cell 71, 1103-1116 (1992).
    • (1992) Cell , vol.71 , pp. 1103-1116
    • Reichmann, E.1
  • 43
    • 0842321501 scopus 로고    scopus 로고
    • MicroRNA targets in Drosophila
    • Enright, A. J. et al. MicroRNA targets in Drosophila. Genome Biol. 5, R1 (2003).
    • (2003) Genome Biol , vol.5
    • Enright, A.J.1
  • 44
    • 2142654329 scopus 로고    scopus 로고
    • MicroRNA-directed cleavage of HOXB8 mRNA
    • Yekta, S., Shih, I. H. & Bartel, D. P. MicroRNA-directed cleavage of HOXB8 mRNA. Science 304, 594-596 (2004).
    • (2004) Science , vol.304 , pp. 594-596
    • Yekta, S.1    Shih, I.H.2    Bartel, D.P.3
  • 45
    • 29144438977 scopus 로고    scopus 로고
    • The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings
    • Ronshaugen, M., Biemar, F., Piel, J., Levine, M. & Lai, E. C. The Drosophila microRNA iab-4 causes a dominant homeotic transformation of halteres to wings. Genes Dev. 19, 2947-2952 (2005).
    • (2005) Genes Dev , vol.19 , pp. 2947-2952
    • Ronshaugen, M.1    Biemar, F.2    Piel, J.3    Levine, M.4    Lai, E.C.5
  • 46
    • 33645525964 scopus 로고    scopus 로고
    • MicroRNA fingerprints during human megakaryocytopoiesis
    • Garzon, R. et al. MicroRNA fingerprints during human megakaryocytopoiesis. Proc. Natl Acad. Sci. USA 103, 5078-5083 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 5078-5083
    • Garzon, R.1
  • 47
    • 0037470044 scopus 로고    scopus 로고
    • Human growth hormone-regulated HOXA1 is a human mammary epithelial oncogene
    • Zhang, X. et al. Human growth hormone-regulated HOXA1 is a human mammary epithelial oncogene. J. Biol. Chem. 278, 7580-7590 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 7580-7590
    • Zhang, X.1
  • 48
    • 0344375083 scopus 로고    scopus 로고
    • Lentivirus-delivered stable gene silencing by RNAi in primary cells
    • Stewart, S. A. et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA 9, 493-501 (2003).
    • (2003) RNA , vol.9 , pp. 493-501
    • Stewart, S.A.1


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