MicroRNA-124 inhibits cancer cell growth through PTB1/PKM1/PKM2 feedback cascade in colorectal cancer

Cancer Letters

Volumn 363, Issue 1, 2015, Pages 17-27

  Taniguchi, Kohei ^a,b   Sugito, Nobuhiko ^a   Kumazaki, Minami ^a   Shinohara, Haruka ^a   Yamada, Nami ^a   Nakagawa, Yoshihito ^c   Ito, Yuko ^b   Otsuki, Yoshinori ^b   Uno, Bunji ^a   Uchiyama, Kazuhisa ^b   Akao, Yukihiro ^a  

^a GIFU UNIVERSITY   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Colorectal cancer; MiR 124; PKM; PTB1; Warburg effect

Indexed keywords

HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; MICRORNA 124; POLYPYRIMIDINE TRACT-BINDING PROTEIN 1; PYRUVATE KINASE; PYRUVATE KINASE MUSCLE 1; PYRUVATE KINASE MUSCLE 2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; CARRIER PROTEIN; MEMBRANE PROTEIN; MICRORNA; MIRN124 MICRORNA, HUMAN; POLYPYRIMIDINE TRACT BINDING PROTEIN; PTBP1 PROTEIN, HUMAN; THYROID HORMONE; THYROID HORMONE-BINDING PROTEINS;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL; CANCER INHIBITION; CANCER PATIENT; COLORECTAL ADENOMA; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; DRUG TARGETING; ENERGY METABOLISM; FEEDBACK SYSTEM; FEMALE; GENE CONTROL; GENE EXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PKM1 GENE; PKM2 GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PTB1 GENE; RNA SPLICING; TUMOR XENOGRAFT; 3' UNTRANSLATED REGION; ANIMAL; BAGG ALBINO MOUSE; CASE CONTROL STUDY; COLORECTAL NEOPLASMS; DRUG SCREENING; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; METABOLISM; NUDE MOUSE; PATHOLOGY; PROCEDURES; RNA INTERFERENCE; TIME; TUMOR CELL LINE; TUMOR VOLUME;

MUS;

3' UNTRANSLATED REGIONS; ANIMALS; APOPTOSIS; AUTOPHAGY; CARRIER PROTEINS; CASE-CONTROL STUDIES; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; ENERGY METABOLISM; FEEDBACK, PHYSIOLOGICAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC THERAPY; HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS; HUMANS; MALE; MEMBRANE PROTEINS; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; OXIDATIVE STRESS; POLYPYRIMIDINE TRACT-BINDING PROTEIN; RNA INTERFERENCE; THYROID HORMONES; TIME FACTORS; TRANSFECTION; TUMOR BURDEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84929042593     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.03.026     Document Type: Article

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